Boris Pasche

Boris Pasche

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Boris Pasche

Boris Pasche

Publications by authors named "Boris Pasche"

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Oncology Navigation Decreases Time to Treatment in Patients with Pancreatic Malignancy.

Ann Surg Oncol 2019 May 16;26(5):1512-1518. Epub 2019 Jan 16.

Department of Surgery, Wake Forest Baptist Medical Center, Winston Salem, NC, USA.

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http://dx.doi.org/10.1245/s10434-019-07157-6DOI Listing
May 2019

Diagnosis of thyroid cancer using deep convolutional neural network models applied to sonographic images: a retrospective, multicohort, diagnostic study.

Lancet Oncol 2019 Feb 21;20(2):193-201. Epub 2018 Dec 21.

Department of Epidemiology and Biostatistics, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy of Tianjin, Tianjin Medical University Cancer Institute and Hospital, Tianjin Medical University, Tianjin, China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S14702045183076
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http://dx.doi.org/10.1016/S1470-2045(18)30762-9DOI Listing
February 2019

Association of MUC16 Mutation With Tumor Mutation Load and Outcomes in Patients With Gastric Cancer.

JAMA Oncol 2018 12;4(12):1691-1698

Department of Epidemiology and Biostatistics, National Clinical Research Center for Cancer, Key Laboratory of Cancer Prevention and Therapy, Tianjin Medical University Cancer Institute and Hospital, Tianjin Medical University, Tianjin, China.

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http://dx.doi.org/10.1001/jamaoncol.2018.2805DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440715PMC
December 2018

Favorable outcome of patients with lung adenocarcinoma harboring POLE mutations and expressing high PD-L1.

Mol Cancer 2018 04 12;17(1):81. Epub 2018 Apr 12.

Center for Cancer Genomics and Precision Oncology, Wake Forest Baptist Comprehensive Cancer Center, Wake Forest Baptist Medical Center, Winston Salem, NC, 27157, USA.

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https://molecular-cancer.biomedcentral.com/articles/10.1186/
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http://dx.doi.org/10.1186/s12943-018-0832-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5897927PMC
April 2018

Safety and tolerability of the first-in-class agent CPI-613 in combination with modified FOLFIRINOX in patients with metastatic pancreatic cancer: a single-centre, open-label, dose-escalation, phase 1 trial.

Lancet Oncol 2017 06 8;18(6):770-778. Epub 2017 May 8.

Section on Hematology and Oncology, Wake Forest University School of Medicine, Winston-Salem, NC, USA; Comprehensive Cancer Center of Wake Forest Baptist Medical Center, Wake Forest University School of Medicine, Winston-Salem, NC, USA; Department of Cancer Biology, Wake Forest University School of Medicine, Winston-Salem, NC, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S14702045173031
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http://dx.doi.org/10.1016/S1470-2045(17)30314-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5635818PMC
June 2017

Lynch Syndrome Testing: A Missed Opportunity in the Era of Precision Medicine.

JAMA 2016 Jul;316(1):38-9

Comprehensive Cancer Center of Wake Forest Baptist Medical Center, Winston Salem, North Carolina3Department of Pathology, Wake Forest Baptist Medical Center, Winston Salem, North Carolina.

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http://jama.jamanetwork.com/article.aspx?doi=10.1001/jama.20
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http://dx.doi.org/10.1001/jama.2016.8291DOI Listing
July 2016

An HF exposure system for mice with improved efficiency.

Bioelectromagnetics 2016 May 31;37(4):223-33. Epub 2016 Mar 31.

IT'IS Foundation, ETH Zürich, Zürich, Switzerland.

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http://dx.doi.org/10.1002/bem.21969DOI Listing
May 2016

TGFBR1 and cancer susceptibility.

Trans Am Clin Climatol Assoc 2014 ;125:300-12

Winston Salem, NC.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4112675PMC
February 2016

Prevention and treatment of cancer with aspirin: where do we stand?

Semin Oncol 2014 Jun 24;41(3):397-401. Epub 2014 Apr 24.

Department of Cancer Biology and Comprehensive Cancer Center, Wake Forest University, Medical Center Blvd, Winston Salem, NC.

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http://dx.doi.org/10.1053/j.seminoncol.2014.04.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4099965PMC
June 2014

Non-small cell lung cancer and precision medicine: a model for the incorporation of genomic features into clinical trial design.

JAMA 2014 May;311(19):1975-6

Division of Hematology/Oncology, Department of Medicine, The University of Alabama at Birmingham.

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http://dx.doi.org/10.1001/jama.2014.3742DOI Listing
May 2014

TGF-β: duality of function between tumor prevention and carcinogenesis.

J Natl Cancer Inst 2014 Feb;106(2):djt369

Affiliations of authors: Department of Medicine, Division of Gastroenterology (DRP, JB, BJ) and Division of Hematology/Oncology (HGM), Department of Surgery, Division of GI Surgical Oncology (DRP, PJG), and Department of Urology (CL), Northwestern University Feinberg School of Medicine, Chicago, IL; Department of Biomedical Engineering. McCormick School of Engineering, Northwestern University, Evanston, IL (DRP); Department of Biomedical Sciences, University of Wisconsin-Milwaukee, Milwaukee, WI (JAD); UMR INSERM U1052, CNRS 5286, Université Lyon 1, Centre de Recherche en Cancérologie de Lyon, Lyon, France (LB); Division of Hematology/Oncology, Department of Medicine, University of Alabama-Birmingham, Birmingham, AL (BP); Department of Pathology and Laboratory Medicine, University of California-Irvine, Irvine, CA (CL).

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http://dx.doi.org/10.1093/jnci/djt369DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3952197PMC
February 2014

SMAD4 is a potential prognostic marker in human breast carcinomas.

Tumour Biol 2014 Jan 24;35(1):641-50. Epub 2013 Aug 24.

The Key Laboratory of Pathobiology, Ministry of Education, Jilin University, Changchun, 130021, China,

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http://dx.doi.org/10.1007/s13277-013-1088-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4142205PMC
January 2014

A two-SNP IL-6 promoter haplotype is associated with increased lung cancer risk.

J Cancer Res Clin Oncol 2013 Feb 2;139(2):231-42. Epub 2012 Oct 2.

Department of Surgery, The First Affiliated Hospital, Soochow University, 188 Shizi Street, Suzhou 215006, People's Republic of China.

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http://dx.doi.org/10.1007/s00432-012-1314-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4535449PMC
February 2013

Aspirin--from prevention to targeted therapy.

Authors:
Boris Pasche

N Engl J Med 2012 Oct;367(17):1650-1

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http://dx.doi.org/10.1056/NEJMe1210322DOI Listing
October 2012

Potential of whole-genome sequencing for determining risk and personalizing therapy: focus on AML.

Expert Rev Anticancer Ther 2012 Oct;12(10):1289-97

Division of Hematology/Oncology, Department of Medicine, University of Alabama at Birmingham and UAB Comprehensive Cancer Center, Birmingham, AL, USA.

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http://dx.doi.org/10.1586/era.12.116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3636990PMC
October 2012

Association between IL6 -174G/C and cancer: A meta-analysis of 105,482 individuals.

Exp Ther Med 2012 Apr 13;3(4):655-664. Epub 2012 Jan 13.

Soochow University Laboratory of Cancer Molecular Genetics, Medical College of Soochow University, Suzhou 215123, P.R. China ;

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http://dx.doi.org/10.3892/etm.2012.454DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3438703PMC
April 2012

Polymorphisms of ADIPOQ and ADIPOR1 and prostate cancer risk.

Metabolism 2011 Sep 12;60(9):1234-43. Epub 2011 Mar 12.

Cancer Genetics Program, Division of Hematology/Oncology, Department of Medicine and Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.

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http://dx.doi.org/10.1016/j.metabol.2011.01.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3134585PMC
September 2011

TGFBR1 signaling and breast cancer.

J Mammary Gland Biol Neoplasia 2011 Jun 5;16(2):89-95. Epub 2011 Apr 5.

Division of Hematology/Oncology, Department of Medicine, The University of Alabama at Birmingham, Birmingham, AL 35294-3300, USA.

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http://dx.doi.org/10.1007/s10911-011-9216-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4753062PMC
June 2011

The role of the fat mass and obesity associated gene (FTO) in breast cancer risk.

BMC Med Genet 2011 Apr 13;12:52. Epub 2011 Apr 13.

Cancer Genetics Program, Division of Hematology/Oncology, Department of Medicine and Robert H, Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, 676 N St Clair st suite 850, Chicago, IL 60611, USA.

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http://dx.doi.org/10.1186/1471-2350-12-52DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3089782PMC
April 2011

Whole-genome sequencing: a step closer to personalized medicine.

JAMA 2011 Apr;305(15):1596-7

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http://dx.doi.org/10.1001/jama.2011.484DOI Listing
April 2011

Bayesian analysis of genetic interactions in case-control studies, with application to adiponectin genes and colorectal cancer risk.

Ann Hum Genet 2011 Jan 15;75(1):90-104. Epub 2010 Sep 15.

Department of Biostatistics, University of Alabama at Birmingham, 35294, USA.

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http://dx.doi.org/10.1111/j.1469-1809.2010.00605.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3005151PMC
January 2011

Tgf-beta signaling alterations and colon cancer.

Cancer Treat Res 2010 ;155:85-103

Division of Hematology/Oncology, Department of Medicine, UAB Comprehensive Cancer Center, The University of Alabama, Birmingham, AL 35294-3300, USA.

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http://dx.doi.org/10.1007/978-1-4419-6033-7_5DOI Listing
September 2010

Cancer genetics. Introduction.

Authors:
Boris Pasche

Cancer Treat Res 2010 ;155:xi-xii

Department of Medicine, UAB Comprehensive Cancer Center, The University of Alabama, Birmingham, AL 35294-3300, USA.

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http://dx.doi.org/10.1007/978-1-4419-6033-7DOI Listing
September 2010

Candidate gene association studies: successes and failures.

Curr Opin Genet Dev 2010 Jun 21;20(3):257-61. Epub 2010 Apr 21.

Division of Hematology/Oncology, Department of Medicine, University of Alabama at Birmingham and UAB Comprehensive Cancer Center, Birmingham, AL 35294-3300, USA.

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http://dx.doi.org/10.1016/j.gde.2010.03.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2885524PMC
June 2010

The cover. Physichromie no. 965.

Authors:
Boris Pasche

JAMA 2010 Mar;303(11):1015

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http://dx.doi.org/10.1001/jama.2010.220DOI Listing
March 2010

TGFBR1 haplotypes and risk of non-small-cell lung cancer.

Cancer Res 2009 Sep 18;69(17):7046-52. Epub 2009 Aug 18.

Laboratory of Medical Genetics, School of Basic Medicine and Biological Sciences, The First Affiliated Hospital, Medical College of Soochow University, Suzhou, PR China.

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http://dx.doi.org/10.1158/0008-5472.CAN-08-4602DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2737098PMC
September 2009

Transforming growth factor beta as a therapeutic target in systemic sclerosis.

Nat Rev Rheumatol 2009 Apr;5(4):200-6

Section ofRheumatology, Department of Medicine, Northwestern University, Feinberg School of Medicine, Chicago, IL 60611, USA.

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http://dx.doi.org/10.1038/nrrheum.2009.26DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3959159PMC
April 2009

Tgfbr1 haploinsufficiency is a potent modifier of colorectal cancer development.

Cancer Res 2009 Jan;69(2):678-86

Department of Medicine, Division of Hematology/Oncology, Comprehensive Cancer Center, The University of Alabama at Birmingham, Birmingham, Alabama 35294-3300, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-08-3980DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2668823PMC
January 2009

Role of polymorphisms in Adamantiades-Behçet's disease.

J Rheumatol 2008 Dec 15;35(12):2376-8. Epub 2008 Oct 15.

Cancer Genetics Program, Division of Hematology/Oncology, Department of Medicine, and Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2646844PMC
December 2008

Antitransforming growth factor-beta therapy in fibrosis: recent progress and implications for systemic sclerosis.

Curr Opin Rheumatol 2008 Nov;20(6):720-8

Department of Medicine and Robert H. Lurie Comprehensive Cancer Center, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, USA.

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http://dx.doi.org/10.1097/BOR.0b013e32830e48e8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4541793PMC
November 2008

Variants of the adiponectin (ADIPOQ) and adiponectin receptor 1 (ADIPOR1) genes and colorectal cancer risk.

JAMA 2008 Oct;300(13):1523-31

Cancer Genetics Program, Division of Hematology and Oncology, Department of Medicine and Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.

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http://dx.doi.org/10.1001/jama.300.13.1523DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2628475PMC
October 2008

Variants of the adiponectin and adiponectin receptor 1 genes and breast cancer risk.

Cancer Res 2008 May;68(9):3178-84

Division of Hematology/Oncology, Department of Medicine, Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-08-0533DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2685173PMC
May 2008

Recent advances in breast cancer genetics.

Authors:
Boris Pasche

Cancer Treat Res 2008 ;141:1-10

Department of Medicine, Robert H. Lurie Comprehensive Cancer Center, Northwestern University Cancer Genetics Program, Chicago, IL 60611, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2637546PMC
http://dx.doi.org/10.1007/978-0-387-73161-2_1DOI Listing
March 2008

TGFBR1*6A enhances the migration and invasion of MCF-7 breast cancer cells through RhoA activation.

Cancer Res 2008 Mar;68(5):1319-28

Cancer Genetics Program, Division of Hematology/Oncology, Department of Medicine, Northwestern University Feinberg School of Medicine, 676 North St. Clair Street, Suite 880, Chicago, IL 60611, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-07-5424DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2673101PMC
March 2008

Somatic acquisition of TGFBR1*6A by epithelial and stromal cells during head and neck and colon cancer development.

Hum Mol Genet 2007 Dec 21;16(24):3128-35. Epub 2007 Sep 21.

Cancer Genetics Program, Division of Hematology/Oncology, Department of Medicine, Northwestern University, Chicago, IL 60611, USA.

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http://dx.doi.org/10.1093/hmg/ddm274DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2637554PMC
December 2007

Targeting transforming growth factor-beta signaling.

Curr Opin Oncol 2007 Nov;19(6):579-85

Cancer Genetics Program, Division of Hematology/Oncology, Department of Medicine and Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, USA.

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http://dx.doi.org/10.1097/CCO.0b013e3282f0ad0eDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2640227PMC
November 2007

TGF-beta signaling alterations and susceptibility to colorectal cancer.

Hum Mol Genet 2007 Apr;16 Spec No 1:R14-20

Cancer Genetics Program, Division of Hematology/Oncology, Department o Medicine, Robert H. Lurie Comprehensive Cancer Center, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.

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http://dx.doi.org/10.1093/hmg/ddl486DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2637552PMC
April 2007

New insights into breast cancer genetics and impact on patient management.

Curr Treat Options Oncol 2007 Feb;8(1):61-73

Cancer Genetics Program, Division of Hematology/Oncology, Department of Medicine and Robert H. Lurie Comprehensive Cancer Center, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.

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http://dx.doi.org/10.1007/s11864-007-0021-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2670199PMC
February 2007

Transforming Growth Factor Beta and breast cancer.

Cancer Treat Res 2005 ;126:129-56

Division of Hematology/Oncology, Robert H Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, IL, USA.

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http://link.springer.com/10.1007/0-387-24361-5_6
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http://dx.doi.org/10.1007/0-387-24361-5_6DOI Listing
November 2005

TGFBR1*6A may contribute to hereditary colorectal cancer.

J Clin Oncol 2005 May;23(13):3074-8

Cancer Genetics Program, Division of Hematology/Oncology, Department of Medicine, Robert H. Lurie Comprehensive Cancer Center, Northwestern University Feinberg School of Medicine, 676 N St Clair St, Suite 880, Chicago, IL 60611, USA.

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http://dx.doi.org/10.1200/JCO.2005.00.281DOI Listing
May 2005

Combined genetic assessment of transforming growth factor-beta signaling pathway variants may predict breast cancer risk.

Cancer Res 2005 Apr;65(8):3454-61

Cancer Genetics Program, Division of Hematology/Oncology, Department of Medicine, Feinberg School of Medicine and Robert H. Lurie Comprehensive Cancer Center, Northwestern University, 676 North St. Clair Street, Chicago, IL 60611, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-04-2961DOI Listing
April 2005

No major association between TGFBR1*6A and prostate cancer.

BMC Genet 2004 Sep 22;5:28. Epub 2004 Sep 22.

Cancer Genetics Program, Division of Hematology/Oncology, Department of Medicine, Robert H. Lurie Comprehensive Cancer Center, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.

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http://dx.doi.org/10.1186/1471-2156-5-28DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC521683PMC
September 2004

Role of TGF-beta in cancer and the potential for therapy and prevention.

Expert Rev Anticancer Ther 2004 Aug;4(4):649-61

Northwestern University Feinberg School of Medicine, Division of Hematology/Oncology, Department of Medicine, Robert H Lurie Comprehensive Cancer Center, 676 N. St Clair Street, Suite 880, Chicago, IL 60611, USA.

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http://dx.doi.org/10.1586/14737140.4.4.649DOI Listing
August 2004

Targeting non-small cell lung cancer with epidermal growth factor tyrosine kinase inhibitors: where do we stand, where do we go.

Crit Rev Oncol Hematol 2004 Jun;50(3):175-86

Department of Medicine, Northwestern University Feinberg School of Medicine and the Robert H Lurie Comprehensive Cancer Center of Northwestern University, Chicago, IL 60611, USA.

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http://dx.doi.org/10.1016/j.critrevonc.2004.02.004DOI Listing
June 2004

TGFBR1*6A and cancer risk: a meta-analysis of seven case-control studies.

J Clin Oncol 2003 Sep;21(17):3236-43

Cancer Genetics Program, Division of Hematology/Oncology, Evanston Northwestern Healthcare, Chicago, IL, USA.

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http://dx.doi.org/10.1200/JCO.2003.11.524DOI Listing
September 2003

TGF-beta signaling alterations in cancer.

Cancer Treat Res 2003 ;115:73-94

Division of Hematology/Oncology, Department of Medicine, Northwestern University Medical School, Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Chicago, IL, USA.

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http://dx.doi.org/10.1007/0-306-48158-8_3DOI Listing
July 2003

Molecular markers in prognosis of colorectal cancer and prediction of response to treatment.

Best Pract Res Clin Gastroenterol 2002 Apr;16(2):331-45

Division of Hematology/Oncology, Department of Medicine, Northwestern University Medical School and Robert H. Lurie Comprehensive Cancer Center of Northwestern University, Chicago, IL-60611, USA.

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http://dx.doi.org/10.1053/bega.2002.0289DOI Listing
April 2002