Boris Novakovic

Boris Novakovic

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Boris Novakovic

Boris Novakovic

Publications by authors named "Boris Novakovic"

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The role of Toll-like receptor 10 in modulation of trained immunity.

Immunology 2020 Mar 26;159(3):289-297. Epub 2019 Nov 26.

Department of Internal Medicine, Radboud Center for Infectious Diseases (RCI), Radboud Institute of Molecular Life Sciences (RIMLS), Radboud University Medical Center, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1111/imm.13145DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7011636PMC
March 2020

The emerging role of epigenetics in the immune response to vaccination and infection: a systematic review.

Epigenetics 2020 Mar 17:1-39. Epub 2020 Mar 17.

Department of Paediatrics, The University of Melbourne, Parkville, Australia.

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http://dx.doi.org/10.1080/15592294.2020.1712814DOI Listing
March 2020

Diabetes in pregnancy and epigenetic mechanisms-how the first 9 months from conception might affect the child's epigenome and later risk of disease.

Lancet Diabetes Endocrinol 2019 Oct 22;7(10):796-806. Epub 2019 May 22.

Cancer and Disease Epigenetics, Murdoch Children's Research Institute, Melbourne, VIC, Australia; Department of Pediatrics, Melbourne University, Melbourne, VIC, Australia.

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http://dx.doi.org/10.1016/S2213-8587(19)30078-6DOI Listing
October 2019

Intrauterine programming of obesity and type 2 diabetes.

Diabetologia 2019 10 27;62(10):1789-1801. Epub 2019 Aug 27.

Murdoch Children's Research Institute, Royal Children's Hospital, Flemington Road, Parkville, VIC, 3052, Australia.

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http://dx.doi.org/10.1007/s00125-019-4951-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6731191PMC
October 2019

Human placental methylome in the interplay of adverse placental health, environmental exposure, and pregnancy outcome.

PLoS Genet 2019 08 1;15(8):e1008236. Epub 2019 Aug 1.

Epigenetics Group, Murdoch Children's Research Institute, Royal Children's Hospital, Parkville, Victoria, Australia.

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http://dx.doi.org/10.1371/journal.pgen.1008236DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6675049PMC
August 2019

Treatment with Statins Does Not Revert Trained Immunity in Patients with Familial Hypercholesterolemia.

Cell Metab 2019 07 13;30(1):1-2. Epub 2019 Jun 13.

Department of Internal Medicine, and Radboud Institute for Molecular Life Sciences (RIMLS), Radboud University Medical Center, Nijmegen 6525GA, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2019.05.014DOI Listing
July 2019

Alkaline soda Lake Velika Rusanda (Serbia): the first insight into diatom diversity of this extreme saline lake.

Extremophiles 2019 May 19;23(3):347-357. Epub 2019 Mar 19.

University of Belgrade, Institute of Chemistry, Technology and Metallurgy, Njegoševa 12, Belgrade, 11000, Serbia.

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http://link.springer.com/10.1007/s00792-019-01088-6
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http://dx.doi.org/10.1007/s00792-019-01088-6DOI Listing
May 2019

A possible role for mitochondrial-derived peptides humanin and MOTS-c in patients with Q fever fatigue syndrome and chronic fatigue syndrome.

J Transl Med 2019 05 14;17(1):157. Epub 2019 May 14.

Radboud Expertise Center for Q Fever, Department of Internal Medicine, Division of Infectious Diseases 463, Radboud University Medical Center, P.O. Box 9101, 6500 HB, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1186/s12967-019-1906-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6518812PMC
May 2019

Extensive epigenomic integration of the glucocorticoid response in primary human monocytes and in vitro derived macrophages.

Sci Rep 2019 02 26;9(1):2772. Epub 2019 Feb 26.

Department of Molecular Biology, Radboud Institute for Molecular Life Sciences, Faculty of Science Radboud University, PO box 9101, 6500 HG, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1038/s41598-019-39395-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6391480PMC
February 2019

The Itaconate Pathway Is a Central Regulatory Node Linking Innate Immune Tolerance and Trained Immunity.

Cell Metab 2019 01 4;29(1):211-220.e5. Epub 2018 Oct 4.

Department of Internal Medicine (463) and Radboud Center for Infectious Diseases (RCI), Radboud University Nijmegen Medical Centre, Geert Grooteplein 8, Nijmegen 6500 HB, the Netherlands; Department for Genomics & Immunoregulation, Life and Medical Sciences Institute (LIMES), University of Bonn, Bonn, Germany; Human Genomics Laboratory, Craiova University of Medicine and Pharmacy, Craiova, Romania.

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https://linkinghub.elsevier.com/retrieve/pii/S15504131183056
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http://dx.doi.org/10.1016/j.cmet.2018.09.003DOI Listing
January 2019

Micromanaging human placental function: differential microRNA expression in feto-placental endothelial cells of gestational diabetes pregnancies.

Clin Sci (Lond) 2019 01 25;133(2):315-319. Epub 2019 Jan 25.

Epigenetics Research, Murdoch Children's Research Institute, Royal Children's Hospital, Flemington Road, Parkville, VIC, 3052, Australia and Department of Paediatrics, University of Melbourne, Parkville, VIC, 3052, Australia

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http://dx.doi.org/10.1042/CS20180901DOI Listing
January 2019

BCG Vaccination Protects against Experimental Viral Infection in Humans through the Induction of Cytokines Associated with Trained Immunity.

Cell Host Microbe 2018 Jan;23(1):89-100.e5

Department of Internal Medicine and Radboud Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, the Netherlands; Department for Genomics & Immunoregulation, Life and Medical Sciences Institute (LIMES), University of Bonn, 53115 Bonn, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.chom.2017.12.010DOI Listing
January 2018

Metabolic Induction of Trained Immunity through the Mevalonate Pathway.

Cell 2018 01;172(1-2):135-146.e9

Department of Internal Medicine, Radboud University Medical Center, 6525 GA Nijmegen, the Netherlands; Department for Genomics & Immunoregulation, Life and Medical Sciences Institute (LIMES), University of Bonn, 53115 Bonn, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2017.11.025DOI Listing
January 2018

I Remember You: Epigenetic Priming in Epithelial Stem Cells.

Immunity 2017 12;47(6):1019-1021

Department of Molecular Biology, Radboud Institute of Molecular Life Sciences and Faculty of Science, Radboud University, 6525 GA Nijmegen, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2017.12.005DOI Listing
December 2017

We Can Still Be Friends: IFN-γ Breaks Up Macrophage Enhancers.

Immunity 2017 08;47(2):209-211

Department of Molecular Biology, Radboud Institute of Molecular Life Sciences and Faculty of Science, Radboud University, 6525 GA Nijmegen, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2017.08.002DOI Listing
August 2017

Increased methylation and decreased expression of homeobox genes TLX1, HOXA10 and DLX5 in human placenta are associated with trophoblast differentiation.

Sci Rep 2017 07 3;7(1):4523. Epub 2017 Jul 3.

Department of Maternal-Fetal Medicine Pregnancy Research Centre, The Royal Women's Hospital, and Department of Obstetrics and Gynaecology, University of Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1038/s41598-017-04776-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5495813PMC
July 2017

Variable gene methylation is a common feature of placental trophoblast differentiation, preeclampsia, and response to hypoxia.

FASEB J 2017 06 21;31(6):2380-2392. Epub 2017 Feb 21.

Cancer and Disease Epigenetics, Murdoch Children's Research Institute, Parkville, Victoria, Australia;

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http://dx.doi.org/10.1096/fj.201601189RRDOI Listing
June 2017

Uric acid priming in human monocytes is driven by the AKT-PRAS40 autophagy pathway.

Proc Natl Acad Sci U S A 2017 05 8;114(21):5485-5490. Epub 2017 May 8.

Department of Internal Medicine, Radboud University Medical Center, 6525 GA Nijmegen, The Netherlands;

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http://dx.doi.org/10.1073/pnas.1620910114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5448210PMC
May 2017

DNA methylation mediated up-regulation of TERRA non-coding RNA is coincident with elongated telomeres in the human placenta.

Mol Hum Reprod 2016 11 7;22(11):791-799. Epub 2016 Sep 7.

Murdoch Childrens Research Institute-Cancer and Disease Epigenetics, Royal Children's Hospital Flemington Road, Parkville, Melbourne, Victoria 3052, Australia

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http://dx.doi.org/10.1093/molehr/gaw053DOI Listing
November 2016

Epigenetic regulation of human placental function and pregnancy outcome: considerations for causal inference.

Am J Obstet Gynecol 2015 Oct;213(4 Suppl):S182-96

Cancer and Disease Epigenetics, Murdoch Childrens Research Institute, Royal Children's Hospital, Parkville, Australia; Department of Pediatrics, University of Melbourne, Parkville, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.ajog.2015.07.011DOI Listing
October 2015

Human active X-specific DNA methylation events showing stability across time and tissues.

Eur J Hum Genet 2014 Dec 9;22(12):1376-81. Epub 2014 Apr 9.

1] Cancer and Disease Epigenetics, Murdoch Childrens Research Institute, Royal Children's Hospital, Parkville, Victoria, Australia [2] Department of Paediatrics, University of Melbourne, Parkville, Victoria, Australia.

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http://dx.doi.org/10.1038/ejhg.2014.34DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4231404PMC
December 2014

Epigenetics as the mediator of fetal programming of adult onset disease: what is the evidence?

Acta Obstet Gynecol Scand 2014 Nov 18;93(11):1090-8. Epub 2014 Jun 18.

Cancer and Disease Epigenetics, Murdoch Childrens Research Institute, Royal Children's Hospital, Parkville, Victoria, Australia; Department of Paediatrics, University of Melbourne, Parkville, Victoria, Australia.

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http://dx.doi.org/10.1111/aogs.12431DOI Listing
November 2014

Assessing global and gene specific DNA methylation in anorexia nervosa: a pilot study.

Int J Eat Disord 2014 Mar 2;47(2):206-10. Epub 2013 Oct 2.

Cancer and Disease Epigenetics, Murdoch Children's Research Institute, Melbourne, Victoria, Australia; Department of Paediatrics, University of Melbourne, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1002/eat.22200DOI Listing
March 2014

Postnatal stability, tissue, and time specific effects of AHRR methylation change in response to maternal smoking in pregnancy.

Epigenetics 2014 Mar 22;9(3):377-86. Epub 2013 Nov 22.

Cancer, Disease and Developmental Epigenetics; Murdoch Childrens Research Institute; Royal Children's Hospital; Parkville, VIC Australia; Department of Paediatrics; University of Melbourne; Parkville, VIC Australia.

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http://dx.doi.org/10.4161/epi.27248DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4053456PMC
March 2014

Placental pseudo-malignancy from a DNA methylation perspective: unanswered questions and future directions.

Front Genet 2013 10;4:285. Epub 2013 Dec 10.

Cancer and Disease Epigenetics, Murdoch Childrens Research Institute, Royal Children's Hospital Parkville, VIC, Australia ; Department of Paediatrics, University of Melbourne Parkville, VIC, Australia.

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http://dx.doi.org/10.3389/fgene.2013.00285DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3857887PMC
December 2013

Association of maternal and nutrient supply line factors with DNA methylation at the imprinted IGF2/H19 locus in multiple tissues of newborn twins.

Epigenetics 2013 Oct 5;8(10):1069-79. Epub 2013 Aug 5.

Department of Paediatrics; University of Melbourne; Parkville, VIC Australia; Early Life Epigenetics Group; Murdoch Childrens Research Institute (MCRI); Royal Children's Hospital; Parkville, VIC Australia.

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http://dx.doi.org/10.4161/epi.25908DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3891688PMC
October 2013

The Peri/postnatal Epigenetic Twins Study (PETS).

Twin Res Hum Genet 2013 Feb 22;16(1):13-20. Epub 2012 Nov 22.

Department of Paediatrics, Royal Children's Hospital, Melbourne, Australia.

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http://dx.doi.org/10.1017/thg.2012.114DOI Listing
February 2013

Glucose as a fetal nutrient: dynamic regulation of several glucose transporter genes by DNA methylation in the human placenta across gestation.

J Nutr Biochem 2013 Jan 15;24(1):282-8. Epub 2012 Aug 15.

Cancer and Disease Epigenetics, Murdoch Childrens Research Institute, Royal Children's Hospital, Parkville, Victoria 3052, Australia.

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http://dx.doi.org/10.1016/j.jnutbio.2012.06.006DOI Listing
January 2013

Maternal vitamin D predominates over genetic factors in determining neonatal circulating vitamin D concentrations.

Am J Clin Nutr 2012 Jul 30;96(1):188-95. Epub 2012 May 30.

Cancer and Disease Epigenetics Group, Murdoch Childrens Research Institute, Royal Children's Hospital, Parkville, Australia.

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http://dx.doi.org/10.3945/ajcn.112.035683DOI Listing
July 2012

Cohort profile: The peri/post-natal epigenetic twins study.

Int J Epidemiol 2012 Feb 3;41(1):55-61. Epub 2011 Oct 3.

Cancer and Disease Epigenetics Group, Murdoch Childrens Research Institute, Royal Children's Hospital, Parkville, Victoria, Australia.

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http://dx.doi.org/10.1093/ije/dyr140DOI Listing
February 2012

Evidence for widespread changes in promoter methylation profile in human placenta in response to increasing gestational age and environmental/stochastic factors.

BMC Genomics 2011 Oct 28;12:529. Epub 2011 Oct 28.

Cancer, Disease and Developmental Epigenetics, Murdoch Childrens Research Institute, Royal Children's Hospital and Department of Paediatrics, University of Melbourne, Parkville, Victoria 3052, Australia.

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http://dx.doi.org/10.1186/1471-2164-12-529DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3216976PMC
October 2011

DNA methylation analysis of multiple tissues from newborn twins reveals both genetic and intrauterine components to variation in the human neonatal epigenome.

Hum Mol Genet 2010 Nov 10;19(21):4176-88. Epub 2010 Aug 10.

Developmental Epigenetics, Murdoch Childrens Research Institute, Royal Children's Hospital, Parkville, Victoria 3052, Australia.

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http://dx.doi.org/10.1093/hmg/ddq336DOI Listing
November 2010

DNA methylation profiling highlights the unique nature of the human placental epigenome.

Epigenomics 2010 Oct;2(5):627-38

Developmental Epigenetics, Murdoch Childrens Research Institute, Royal Children's Hospital & Department of Paediatrics, University of Melbourne, Parkville, Victoria, 3052, Australia.

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http://dx.doi.org/10.2217/epi.10.45DOI Listing
October 2010

Placenta-specific methylation of the vitamin D 24-hydroxylase gene: implications for feedback autoregulation of active vitamin D levels at the fetomaternal interface.

J Biol Chem 2009 May 23;284(22):14838-48. Epub 2009 Feb 23.

Developmental Epigenetics, Murdoch Childrens Research Institute, Royal Children's Hospital, and Department of Paediatrics, University of Melbourne, Parkville, Victoria 3052, Australia.

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http://dx.doi.org/10.1074/jbc.M809542200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2685665PMC
May 2009