Publications by authors named "Boon Tin Chua"

15Publications

CIDE family proteins control lipid homeostasis and the development of metabolic diseases.

Traffic 2020 01;21(1):94-105

State Key Laboratory of Membrane Biology and Tsinghua-Peking Center for Life Sciences, Beijing Advanced Innovation Center for Structural Biology, School of Life Sciences, Tsinghua University, Beijing, China.

View Article and Find Full Text PDF
January 2020

DFCP1 associates with lipid droplets.

Cell Biol Int 2019 Jul 10. Epub 2019 Jul 10.

State Key Laboratory of Membrane Biology and Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, 100084, Beijing, China.

View Article and Find Full Text PDF
July 2019

Identification of gene products that control lipid droplet size in yeast using a high-throughput quantitative image analysis.

Biochim Biophys Acta Mol Cell Biol Lipids 2019 02 7;1864(2):113-127. Epub 2018 Nov 7.

State Key Laboratory of Membrane Biology and Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing 100084, China. Electronic address:

View Article and Find Full Text PDF
February 2019

Polybasic RKKR motif in the linker region of lipid droplet (LD)-associated protein CIDEC inhibits LD fusion activity by interacting with acidic phospholipids.

J Biol Chem 2018 12 25;293(50):19330-19343. Epub 2018 Oct 25.

From the State Key Laboratory of Membrane Biology and Tsinghua-Peking Center for Life Sciences, Beijing Advanced Innovation Center for Structural Biology, School of Life Sciences, Tsinghua University, Beijing 100084,

View Article and Find Full Text PDF
December 2018

Overexpression of Tyro3 and its implications on hepatocellular carcinoma progression.

Int J Oncol 2016 Jan 13;48(1):358-66. Epub 2015 Nov 13.

Department of Pharmacy, Faculty of Science, National University of Singapore, Singapore 117543, Republic of Singapore.

View Article and Find Full Text PDF
January 2016

Benzylidene-indolinones are effective as multi-targeted kinase inhibitor therapeutics against hepatocellular carcinoma.

Mol Oncol 2014 Oct 2;8(7):1266-77. Epub 2014 May 2.

Singapore OncoGenome Laboratory, Institute of Molecular and Cell Biology, A*STAR, Singapore; Department of Molecular Biology, Max-Planck-Institute of Biochemistry, Martinsried, Germany.

View Article and Find Full Text PDF
October 2014

Bosutinib inhibits migration and invasion via ACK1 in KRAS mutant non-small cell lung cancer.

Mol Cancer 2014 Jan 24;13:13. Epub 2014 Jan 24.

Singapore OncoGenome Laboratory, Institute of Medical Biology, Agency of Science Technology and Research, Singapore, Singapore.

View Article and Find Full Text PDF
January 2014

Current strategies for inhibiting FGFR activities in clinical applications: opportunities, challenges and toxicological considerations.

Drug Discov Today 2014 Jan 6;19(1):51-62. Epub 2013 Aug 6.

Singapore Oncogenome Labratory, 61 Biopolis Drive, Singapore 138673, Singapore.

View Article and Find Full Text PDF
January 2014

Somatic mutation in the ACK1 ubiquitin association domain enhances oncogenic signaling through EGFR regulation in renal cancer derived cells.

Mol Oncol 2010 Aug 19;4(4):323-34. Epub 2010 Mar 19.

Singapore OncoGenome Project, Institute of Medical Biology, A* STAR, 8A Biomedical Grove, #06-06 Immunos, Singapore 138648, Singapore.

View Article and Find Full Text PDF
August 2010

Regulation of Akt(ser473) phosphorylation by choline kinase in breast carcinoma cells.

Mol Cancer 2009 Dec 31;8:131. Epub 2009 Dec 31.

Singapore OncoGenome Project, Institute of Medical Biology, A*STAR, 8A Biomedical Grove, 06-06 Immunos, Singapore.

View Article and Find Full Text PDF
December 2009

Mitochondrial translocation of cofilin is an early step in apoptosis induction.

Nat Cell Biol 2003 Dec 23;5(12):1083-9. Epub 2003 Nov 23.

Laboratory of Apoptosis Regulation, Institute of Molecular and Cell Biology, National Institute of Singapore, 30 Medical Drive, 117609, Singapore.

View Article and Find Full Text PDF
December 2003