Boon Tin Chua

CIDE family proteins control lipid homeostasis and the development of metabolic diseases.

Authors:

Feng-Jung Chen Yesheng Yin Boon Tin Chua Peng Li

Traffic 2020 01;21(1):94-105

State Key Laboratory of Membrane Biology and Tsinghua-Peking Center for Life Sciences, Beijing Advanced Innovation Center for Structural Biology, School of Life Sciences, Tsinghua University, Beijing, China.

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January 2020

DFCP1 associates with lipid droplets.

Authors:

Guangang Gao Yuanyuan Sheng Hongyuan Yang Boon Tin Chua Li Xu

Cell Biol Int 2019 Jul 10. Epub 2019 Jul 10.

State Key Laboratory of Membrane Biology and Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, 100084, Beijing, China.

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July 2019

Identification of gene products that control lipid droplet size in yeast using a high-throughput quantitative image analysis.

Authors:

Xuchao Lv Jiaming Liu Yiran Qin Yizhang Liu Meijun Jin Junbiao Dai Boon Tin Chua Hongyuan Yang Peng Li

Biochim Biophys Acta Mol Cell Biol Lipids 2019 02 7;1864(2):113-127. Epub 2018 Nov 7.

State Key Laboratory of Membrane Biology and Tsinghua-Peking Center for Life Sciences, School of Life Sciences, Tsinghua University, Beijing 100084, China. Electronic address:

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February 2019

Polybasic RKKR motif in the linker region of lipid droplet (LD)-associated protein CIDEC inhibits LD fusion activity by interacting with acidic phospholipids.

Authors:

Jia Wang Chengsong Yan Chenqi Xu Boon Tin Chua Peng Li Feng-Jung Chen

J Biol Chem 2018 12 25;293(50):19330-19343. Epub 2018 Oct 25.

From the State Key Laboratory of Membrane Biology and Tsinghua-Peking Center for Life Sciences, Beijing Advanced Innovation Center for Structural Biology, School of Life Sciences, Tsinghua University, Beijing 100084,

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December 2018

Primary angle closure glaucoma (PACG) susceptibility gene PLEKHA7 encodes a novel Rac1/Cdc42 GAP that modulates cell migration and blood-aqueous barrier function.

Authors:

Mei-Chin Lee William Shei Anita S Chan Boon-Tin Chua Shuang-Ru Goh Yaan-Fun Chong Maryam H Hilmy Monisha E Nongpiur Mani Baskaran Chiea-Chuen Khor Tin Aung Walter Hunziker Eranga N Vithana

Hum Mol Genet 2017 10;26(20):4011-4027

Ocular Genetics Research Group, Singapore Eye Research Institute, Singapore 169856, Singapore.

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October 2017

Long noncoding RNA EGFR-AS1 mediates epidermal growth factor receptor addiction and modulates treatment response in squamous cell carcinoma.

Nat Med 2017 Oct 18;23(10):1167-1175. Epub 2017 Sep 18.

Cancer Therapeutics Research Laboratory, National Cancer Centre Singapore, Singapore.

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October 2017

Overexpression of Tyro3 and its implications on hepatocellular carcinoma progression.

Authors:

Yan Duan Winnie Wong Sonja Courtney Chua Hwee Lin Wee Seng Gee Lim Boon Tin Chua Han Kiat Ho

Int J Oncol 2016 Jan 13;48(1):358-66. Epub 2015 Nov 13.

Department of Pharmacy, Faculty of Science, National University of Singapore, Singapore 117543, Republic of Singapore.

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January 2016

Benzylidene-indolinones are effective as multi-targeted kinase inhibitor therapeutics against hepatocellular carcinoma.

Authors:

Han Kiat Ho Boon Tin Chua Winnie Wong Kah Suan Lim Vivian Teo Hooi-Tin Ong Xiao Chen Wei Zhang Kam M Hui Mei Lin Go Axel Ullrich

Mol Oncol 2014 Oct 2;8(7):1266-77. Epub 2014 May 2.

Singapore OncoGenome Laboratory, Institute of Molecular and Cell Biology, A*STAR, Singapore; Department of Molecular Biology, Max-Planck-Institute of Biochemistry, Martinsried, Germany.

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October 2014