Boon Cher Goh

Boon Cher Goh

UNVERIFIED PROFILE

Are you Boon Cher Goh?   Register this Author

Register author
Boon Cher Goh

Boon Cher Goh

Publications by authors named "Boon Cher Goh"

Are you Boon Cher Goh?   Register this Author

100Publications

3922Reads

6Profile Views

Population diversity in oncology drug responses and implications to drug development.

Chin Clin Oncol 2019 Jun;8(3):24

Department of Haematology-Oncology, National University Cancer Institute Singapore, Singapore; Cancer Science of Institute, National University of Singapore, Singapore; Department of Pharmacology, National University of Singapore, Singapore.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.21037/cco.2019.05.01DOI Listing
June 2019

Role of tumor-derived exosomes in cancer metastasis.

Biochim Biophys Acta Rev Cancer 2019 01 9;1871(1):12-19. Epub 2018 Nov 9.

Cancer Science Institute of Singapore, National University of Singapore, Singapore; Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, 117600, Singapore. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S0304419X183015
Publisher Site
http://dx.doi.org/10.1016/j.bbcan.2018.10.004DOI Listing
January 2019

Targeting STAT3 and oxidative phosphorylation in oncogene-addicted tumors.

Redox Biol 2018 Dec 13:101073. Epub 2018 Dec 13.

Department of Haematology-Oncology, National University Health System, Singapore; Haematology-Oncology Research Group, National University Cancer Institute of Singapore, National University Health System, Singapore; Cancer Science Institute, Singapore. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S22132317183090
Publisher Site
http://dx.doi.org/10.1016/j.redox.2018.101073DOI Listing
December 2018

Metabolic reprogramming of oncogene-addicted cancer cells to OXPHOS as a mechanism of drug resistance.

Redox Biol 2018 Dec 17:101076. Epub 2018 Dec 17.

Department of Physiology and Medical Science Cluster Cancer ProgramYong Loo Lin School of Medicine, National University of Singapore, Singapore 119753, Singapore; NUS Graduate School for Integrative Sciences and Engineering, Singapore 117456, Singapore; National University Cancer Institute, National University Health System, Singapore 119074, Singapore; Curtin Health Innovation Research Institute and School of Pharmacy and Biomedical Sciences, Curtin University, Perth 6102, Australia. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S22132317183107
Publisher Site
http://dx.doi.org/10.1016/j.redox.2018.101076DOI Listing
December 2018

Time course and clinical characterization of cisplatin-induced ototoxicity after treatment for nasopharyngeal carcinoma in a South East Asian population.

Head Neck 2018 07 16;40(7):1425-1433. Epub 2018 Feb 16.

Translational Laboratory in Genetic Medicine, Agency for Science, Technology, and Research, Singapore.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/hed.25112DOI Listing
July 2018

Potential role of genipin in cancer therapy.

Pharmacol Res 2018 07 24;133:195-200. Epub 2018 May 24.

Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, 117600, Singapore. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.phrs.2018.05.007DOI Listing
July 2018

Modulation of diverse oncogenic transcription factors by thymoquinone, an essential oil compound isolated from the seeds of Nigella sativa Linn.

Pharmacol Res 2018 07 21;133:213-214. Epub 2018 May 21.

Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117600, Singapore; School of Biomedical Sciences, Curtin Health Innovation Research Institute, Curtin University, Perth, WA 6009, Australia. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S10436618183066
Publisher Site
http://dx.doi.org/10.1016/j.phrs.2018.05.004DOI Listing
July 2018

Antitumor Activity of Nivolumab in Recurrent and Metastatic Nasopharyngeal Carcinoma: An International, Multicenter Study of the Mayo Clinic Phase 2 Consortium (NCI-9742).

J Clin Oncol 2018 05 27;36(14):1412-1418. Epub 2018 Mar 27.

Brigette B.Y. Ma, Edwin P. Hui, Kwok-Wai Lo, Ka-Fai To, K.C. Allen Chan, Y.M. Dennis Lo, Ann D. King, and Anthony T.C. Chan, The Chinese University of Hong Kong, Shatin, Hong Kong, Special Administrative Region, People's Republic of China; Wan-Teck Lim, National Cancer Centre; Boon-Cher Goh, National University Cancer Institute of Singapore; Alex Y.C. Chang, Johns Hopkins University School of Medicine; Akhil Chopra, OncoCare Cancer Centre, Singapore; Adam Pettinger, Nathan R. Foster, Charles Erlichman, Jun Yin, and Brian A. Costello, Mayo Clinic, Rochester, MN; Jonathan W. Riess, University of California Davis Comprehensive Cancer Center, Sacramento; Barbara J. Gitlitz, University of Southern California Keck School of Medicine, Los Angeles; Dean W. Lim, City of Hope Comprehensive Cancer Center, Duarte, CA; Mark Agulnik, Northwestern University, Evanston, IL; Julie A. Kish and Christine H. Chung, Moffitt Cancer Center, University of South Florida, Tampa, FL; Douglas R. Adkins, Washington University School of Medicine, St Louis, MO; Kevin J. Cullen, University of Maryland, Baltimore, MD.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1200/JCO.2017.77.0388DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5941615PMC
May 2018

Modulation of diverse oncogenic transcription factors by thymoquinone, an essential oil compound isolated from the seeds of Nigella sativa Linn.

Pharmacol Res 2018 03 21;129:357-364. Epub 2017 Nov 21.

Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, 117600, Singapore; School of Biomedical Sciences, Curtin Health Innovation Research Institute, Curtin University, Perth, Western Australia 6009, Australia. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.phrs.2017.11.023DOI Listing
March 2018

Dual role of autophagy in hallmarks of cancer.

Oncogene 2018 03 19;37(9):1142-1158. Epub 2017 Dec 19.

Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41388-017-0046-6DOI Listing
March 2018

Pan-HDAC inhibition by panobinostat mediates chemosensitization to carboplatin in non-small cell lung cancer via attenuation of EGFR signaling.

Cancer Lett 2018 03 4;417:152-160. Epub 2018 Jan 4.

Cancer Science Institute of Singapore, National University of Singapore, Singapore; Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore; Department of Haematology-Oncology, National University Cancer Institute, Singapore, Singapore. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.canlet.2017.12.030DOI Listing
March 2018

Third generation EGFR TKIs: current data and future directions.

Mol Cancer 2018 02 19;17(1):29. Epub 2018 Feb 19.

Department of Haematology-Oncology, National University Cancer Institute of Singapore, National University Health System, 1E Kent Ridge Road, NUHS Tower Block, Level 7, Singapore, 119228, Singapore.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12943-018-0778-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5817792PMC
February 2018

Prognostic stratification of patients with metastatic nasopharyngeal carcinoma using a clinical and biochemical scoring system.

J Cancer Res Clin Oncol 2017 Dec 28;143(12):2563-2570. Epub 2017 Aug 28.

Department of Otolaryngology-Head and Neck Surgery, National University Health System, 1E Kent Ridge Road, NUHS Tower Block Level 7, Singapore, 119228, Singapore.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00432-017-2496-1DOI Listing
December 2017

Do STAT3 inhibitors have potential in the future for cancer therapy?

Expert Opin Investig Drugs 2017 08 17;26(8):883-887. Epub 2017 Jul 17.

a Department of Haematology-Oncology , National University Health System , Singapore.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/13543784.2017.1351941DOI Listing
August 2017

Exosomes in Cancer Nanomedicine and Immunotherapy: Prospects and Challenges.

Trends Biotechnol 2017 07 29;35(7):665-676. Epub 2017 Mar 29.

Cancer Science Institute of Singapore, National University of Singapore, Singapore; Department of Hematology-Oncology, National University Cancer Institute, Singapore; Department of Pharmacology, Yong Loo Lin School of Medicine, National University Health System, Singapore; Developmental Therapeutics Unit, National University Cancer Institute, Singapore.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S01677799173004
Publisher Site
http://dx.doi.org/10.1016/j.tibtech.2017.03.004DOI Listing
July 2017

Wanted DEAD/H or Alive: Helicases Winding Up in Cancers.

J Natl Cancer Inst 2017 01 25;109(6). Epub 2017 Jan 25.

Affiliations of authors: Cancer Science Institute of Singapore, National University of Singapore, Singapore (WC, GR, SSS, CW, YY, TZT, HY, BCG, TB, APK); Departments of Pharmacology (WC, GR, SSS, CW, BCG, GS, APK), Physiology (ZXC, ZC, CTY), and Biochemistry (VT), Yong Loo Lin School of Medicine, National University of Singapore, Singapore; KK Women's and Children's Hospital, Singapore (ZXC); Stem Cell and Cancer Biology Laboratory (FA), School of Biomedical Sciences (GS, APK), Curtin Health Innovation Research Institute, Curtin Medical School (APK), Curtin University, Perth, WA, Australia; National University Cancer Institute, National University Health System, Singapore (CTY, BCG, APK); 2 Department of Pediatrics, Semmelweis University, Budapest, Hungary (LSP); MTA TTK Lendület Cancer Biomarker Research Group, Research Centre for Natural Sciences, Budapest, Hungary (LSP); Department of Renal Medicine (MBL) and Department of Haematology-Oncology (BCG), National University Health System, Singapore; Institute of Molecular and Cell Biology (IMCB), A*STAR (Agency for Science, Technology and Research), Singapore (VT); Centre for Cancer Biology, University of South Australia and SA Pathology, Adelaide, Australia (VT); Department of Biological Sciences, University of North Texas, Denton, TX (APK).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/jnci/djw278DOI Listing
January 2017

High-risk HPV genotypes and P16INK4a expression in a cohort of head and neck squamous cell carcinoma patients in Singapore.

Oncotarget 2016 Dec;7(52):86730-86739

Department of Otolaryngology-Head and Neck Surgery, National University Health System Singapore, Singapore 119228.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.18632/oncotarget.13502DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349949PMC
December 2016

UGT1A1 Mediated Drug Interactions and its Clinical Relevance.

Curr Drug Metab 2016 ;17(2):100-6

Cancer Science Institute of Singapore, National University of Singapore, P.O. Box: 117599, Singapore, Singapore.

View Article

Download full-text PDF

Source
October 2016

A novel combinatorial strategy using Seliciclib(®) and Belinostat(®) for eradication of non-small cell lung cancer via apoptosis induction and BID activation.

Cancer Lett 2016 10 25;381(1):49-57. Epub 2016 Jul 25.

Cancer Science Institute of Singapore, National University of Singapore, Singapore; Department of Pharmacology, National University of Singapore, Singapore; Department of Hematology & Oncology, National University Health System, Singapore. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.canlet.2016.07.023DOI Listing
October 2016

Capecitabine pharmacogenetics: historical milestones and progress toward clinical implementation.

Pharmacogenomics 2016 10 27;17(15):1607-1610. Epub 2016 Sep 27.

Department of Haematology-Oncology, National University Cancer Institute, Singapore 119228.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2217/pgs-2016-0133DOI Listing
October 2016

A Retrospective Study in Adults with Metabolic Syndrome: Diabetic Risk Factor Response to Daily Consumption of Agaricus bisporus (White Button Mushrooms).

Plant Foods Hum Nutr 2016 Sep;71(3):245-51

Department of Medicine, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, Box 1147, New York, NY, 10029, USA.

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s11130-016-0552-7
Publisher Site
http://dx.doi.org/10.1007/s11130-016-0552-7DOI Listing
September 2016

Evolving landscape of tumor molecular profiling for personalized cancer therapy: a comprehensive review.

Expert Opin Drug Metab Toxicol 2016 Aug 13;12(8):911-22. Epub 2016 Jun 13.

a Department of Haematology-Oncology , National University Cancer Institute, National University Health System , Singapore , Singapore.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/17425255.2016.1196187DOI Listing
August 2016

Genetic factors affecting drug disposition in Asian cancer patients.

Expert Opin Drug Metab Toxicol 2015 7;11(12):1879-92. Epub 2015 Nov 7.

a Department of Haematology-Oncology , National University Cancer Institute , Singapore 119228.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1517/17425255.2015.1108964DOI Listing
July 2016

Exosome-Mediated Metastasis: From Epithelial-Mesenchymal Transition to Escape from Immunosurveillance.

Trends Pharmacol Sci 2016 07 3;37(7):606-617. Epub 2016 May 3.

Cancer Science Institute of Singapore, Centre for Translational Medicine, National University of Singapore, 14 Medical Drive, #12-01, Singapore 117599, Singapore; Department of Haematology-Oncology, National University Cancer Institute, 1E Kent Ridge Road, NUHS Tower Block, Level 7, Singapore 119228, Singapore; Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117600, Singapore.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.tips.2016.04.006DOI Listing
July 2016

Targeting transcription factor STAT3 for cancer prevention and therapy.

Pharmacol Ther 2016 06 12;162:86-97. Epub 2016 Feb 12.

Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore; School of Biomedical Sciences, CHIRI Biosciences Research Precinct, Curtin University, WA 6009, Australia. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.pharmthera.2015.10.004DOI Listing
June 2016

(68)Ga-DOTA-peptide: A novel molecular biomarker for nasopharyngeal carcinoma.

Head Neck 2016 Apr 14;38(4):E76-80. Epub 2015 Aug 14.

Nuclear Medicine and PET Centre, Mount Elizabeth Hospital, Singapore.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/hed.24164DOI Listing
April 2016

Clinical Outcome among Nasopharyngeal Cancer Patients in a Multi-Ethnic Society in Singapore.

PLoS One 2015 12;10(5):e0126108. Epub 2015 May 12.

Department of Otolaryngology-Head and Neck Surgery, National University Health System, Singapore, Singapore.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0126108PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4428880PMC
February 2016

Validation of a rapid and sensitive LC-MS/MS method for determination of exemestane and its metabolites, 17β-hydroxyexemestane and 17β-hydroxyexemestane-17-O-β-D-glucuronide: application to human pharmacokinetics study.

PLoS One 2015 20;10(3):e0118553. Epub 2015 Mar 20.

Cancer Science Institute of Singapore, National University of Singapore, 14 Medical Drive, Singapore 117599, Singapore; Department of Pharmacology, Yong Loo Lin School of Medicine, National University Health System, Singapore 117599, Singapore; Department of Haematology & Oncology, National University Health System, Singapore 119074, Singapore.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0118553PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4368747PMC
December 2015

Pharmacogenetic versus clinical dosing of warfarin in individuals of Chinese and African-American ancestry: assessment using data simulation.

Pharmacogenet Genomics 2015 Oct;25(10):491-500

aCancer Science Institute of Singapore bDepartment of Medicine cDepartment of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore dDepartment of Haematology-Oncology, National University Cancer Institute eTranslational Laboratory for Genetic Medicine, National University of Singapore and the Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/FPC.0000000000000165DOI Listing
October 2015

MEK Inhibition Overcomes Cisplatin Resistance Conferred by SOS/MAPK Pathway Activation in Squamous Cell Carcinoma.

Mol Cancer Ther 2015 Jul 4;14(7):1750-60. Epub 2015 May 4.

Cancer Science Institute of Singapore, National University of Singapore, Singapore. Department of Hematology-Oncology, National University Hospital, Singapore. National University Cancer Institute, Singapore.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1535-7163.MCT-15-0062DOI Listing
July 2015

Correlation between (68)Ga-DOTA-NOC PET/CT and (18)F-FDG PET/CT in EBV-positive undifferentiated nasopharyngeal carcinoma.

Eur J Nucl Med Mol Imaging 2015 Jun 14;42(7):1162-3. Epub 2015 Feb 14.

Department of Diagnostic Imaging, National University Hospital, 5 Lower Kent Ridge Road, Singapore, 119074, Singapore,

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00259-015-3012-yDOI Listing
June 2015

Garcinol: Current status of its anti-oxidative, anti-inflammatory and anti-cancer effects.

Cancer Lett 2015 Jun 18;362(1):8-14. Epub 2015 Mar 18.

Cancer Science Institute of Singapore, National University of Singapore, Singapore 117599; Department of Pharmacology, National University Health System, Singapore 117597; Department of Haematology-Oncology, National University Health System, Singapore 119228. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.canlet.2015.03.019DOI Listing
June 2015

Ascochlorin, an isoprenoid antibiotic inhibits growth and invasion of hepatocellular carcinoma by targeting STAT3 signaling cascade through the induction of PIAS3.

Mol Oncol 2015 Apr 5;9(4):818-33. Epub 2015 Jan 5.

Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117597, Singapore; School of Biomedical Sciences, Faculty of Health Sciences, Curtin University, Western Australia 6009, Australia. Electronic address:

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1016/j.molonc.2014.12.008
Publisher Site
http://dx.doi.org/10.1016/j.molonc.2014.12.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5528777PMC
April 2015

Erratum to: does saturable formation of gemcitabine triphosphate occur in patients?

Cancer Chemother Pharmacol 2015 Mar;75(3):657

Department of Hematology-Oncology, National University Hospital, Singapore, Singapore,

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00280-015-2678-yDOI Listing
March 2015

Improving Wait Times for Elective Chemotherapy Through Pre-Preparation: A Quality-Improvement Project at the National University Cancer Institute of Singapore.

J Oncol Pract 2015 01 2;11(1):e89-94. Epub 2014 Dec 2.

National University Cancer Institute; and National University Health System, Singapore, Singapore.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1200/JOP.2014.000356DOI Listing
January 2015

The genomic landscape of nasopharyngeal carcinoma.

Nat Genet 2014 Aug 22;46(8):866-71. Epub 2014 Jun 22.

1] Cancer Science Institute of Singapore, National University of Singapore, Singapore. [2] Division of Hematology/Oncology, Cedars-Sinai Medical Center, University of California, Los Angeles School of Medicine, Los Angeles, California, USA. [3] National University Cancer Institute, National University Hospital Singapore, Singapore. [4].

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ng.3006DOI Listing
August 2014

Effect of mushroom diet on pharmacokinetics of gabapentin in healthy Chinese subjects.

Br J Clin Pharmacol 2014 Jul;78(1):129-34

Faculty of Pharmacy, University of Sydney, Sydney, NSW, 2006, Australia; Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/bcp.12273DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4168387PMC
July 2014

A multicenter phase 2 trial of pazopanib in metastatic and progressive medullary thyroid carcinoma: MC057H.

J Clin Endocrinol Metab 2014 May 25;99(5):1687-93. Epub 2014 Feb 25.

Division of Medical Oncology (K.C.B., J.R.M., J.R., K.S., J.K.B., K.P.W., C.R.I., C.E.), Division of Biomedical Statistics and Informatics (V.J.S.), Division of Endocrinology (J.C.M., B.M., I.H., V.F.), Mayo Clinic, Rochester, Minnesota 55905; Division of Endocrinology (R.C.S.), Division of Medical Oncology (W.J.M., M.E.M., C.B.), Mayo Clinic Florida, Jacksonville, Florida 32224; Division of Medical Oncology (N.K.), Mayo Clinic Arizona, Scottsdale, Arizona 85259; Carbone Cancer Center (A.M.T.), University of Wisconsin, Madison Wisconsin 53705; Minnesota Oncology Hematology (P.J.F.), PA, Minneapolis, Minnesota 55407; National University Hospital (C.G.), Singapore 119228; and Cancer Therapy Evaluation Program (P.H.), National Cancer Institute, Bethesda, Maryland 20892.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1210/jc.2013-3713DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4010705PMC
May 2014

CYP3A5*3 and bilirubin predict midazolam population pharmacokinetics in Asian cancer patients.

J Clin Pharmacol 2014 Feb 17;54(2):215-24. Epub 2013 Dec 17.

Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore; Defence Medical & Environmental Research Institute, DSO National Laboratories, Singapore, Singapore.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jcph.230DOI Listing
February 2014

UGT1A6 polymorphisms modulated lung cancer risk in a Chinese population.

PLoS One 2012 17;7(8):e42873. Epub 2012 Aug 17.

Department of Haematology-Oncology, National University Cancer Institute of Singapore, Singapore, Singapore.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0042873PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3422233PMC
April 2013

Quantification of L-ergothioneine in human plasma and erythrocytes by liquid chromatography-tandem mass spectrometry.

J Mass Spectrom 2013 Mar;48(3):406-12

Cancer Science Institute of Singapore, National University of Singapore, 14 Medical Drive, Singapore, 117599, Singapore.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jms.3150DOI Listing
March 2013

Pharmacologic modulation strategies to reduce dose requirements of anticancer therapy while preserving clinical efficacy.

Future Oncol 2012 Jun;8(6):731-49

Department of Haematology-Oncology, National University Cancer Institute, National University Health System, Singapore.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2217/fon.12.53DOI Listing
June 2012

A case of Sweet's syndrome due to 5-Azacytidine and vorinostat in a patient with NK/T cell lymphoma.

Cutan Ocul Toxicol 2012 Mar 26;31(1):64-6. Epub 2011 Aug 26.

Department of Hematology-Oncology, National University Health System, 1E Kent Ridge Road, Singapore.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3109/15569527.2011.602034DOI Listing
March 2012

Gemcitabine and platinum pathway pharmacogenetics in Asian breast cancer patients.

Cancer Genomics Proteomics 2011 Sep-Oct;8(5):255-9

Department of Hematology-Oncology, National University Cancer Institute of Singapore.

View Article

Download full-text PDF

Source
February 2012

Population pharmacokinetics of modafinil and its acid and sulfone metabolites in Chinese males.

Ther Drug Monit 2011 Dec;33(6):719-29

Bioengineering Laboratory, Defence Medical and Environmental Research Institute, DSO National Laboratories, Singapore.

View Article

Download full-text PDF

Source
http://content.wkhealth.com/linkback/openurl?sid=WKPTLP:land
Publisher Site
http://dx.doi.org/10.1097/FTD.0b013e318237a9e9DOI Listing
December 2011

Impact of UDP-gluconoryltransferase 2B17 genotype on vorinostat metabolism and clinical outcomes in Asian women with breast cancer.

Pharmacogenet Genomics 2011 Nov;21(11):760-8

Department of Medical Oncology, National Cancer Centre, National University of Singapore, Singapore.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/FPC.0b013e32834a8639DOI Listing
November 2011

Pharmacokinetic modeling of plasma and intracellular concentrations of raltegravir in healthy volunteers.

Antimicrob Agents Chemother 2011 Sep 11;55(9):4090-5. Epub 2011 Jul 11.

Cancer Science Institute of Singapore, National University of Singapore, 28 Medical Drive, Singapore 117456.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/AAC.00593-11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3165315PMC
September 2011

Pharmacogenetics for oncology practice.

Ann Acad Med Singapore 2011 Aug;40(8):348-9

View Article

Download full-text PDF

Source
August 2011

Rapid determination of gefitinib and its main metabolite, O-desmethyl gefitinib in human plasma using liquid chromatography-tandem mass spectrometry.

J Chromatogr B Analyt Technol Biomed Life Sci 2011 Jul 12;879(22):2155-61. Epub 2011 Jun 12.

Cancer Science Institute of Singapore, National University of Singapore, Singapore.

View Article

Download full-text PDF

Source
http://linkinghub.elsevier.com/retrieve/pii/S157002321100373
Publisher Site
http://dx.doi.org/10.1016/j.jchromb.2011.05.056DOI Listing
July 2011

Comparison of the pharmacokinetics and pharmacodynamics of S-1 between Caucasian and East Asian patients.

Cancer Sci 2011 Feb 10;102(2):478-83. Epub 2010 Dec 10.

Department of Hematology-Oncology, National University Health System, Cancer Sciences Institute of Singapore, National University of Singapore, Singapore.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/j.1349-7006.2010.01793.xDOI Listing
February 2011

Simultaneous determination of raltegravir and raltegravir glucuronide in human plasma by liquid chromatography-tandem mass spectrometric method.

J Mass Spectrom 2011 Feb 24;46(2):202-8. Epub 2011 Jan 24.

Cancer Science Institute of Singapore, National University of Singapore, 28 Medical Drive, Singapore 117456, Singapore.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/jms.1874
Publisher Site
http://dx.doi.org/10.1002/jms.1874DOI Listing
February 2011

Exon sequencing and association analysis of EPHX1 genetic variants with maintenance warfarin dose in a multiethnic Asian population.

Pharmacogenet Genomics 2011 Jan;21(1):35-41

Department of Epidemiology and Public Health, National University of Singapore, Singapore.

View Article

Download full-text PDF

Source
January 2011

A sensitive and specific liquid chromatography-tandem mass spectrometric method for determination of belinostat in plasma from liver cancer patients.

J Chromatogr B Analyt Technol Biomed Life Sci 2010 Sep 30;878(26):2409-14. Epub 2010 Jul 30.

Cancer Science Institute of Singapore, National University of Singapore, Singapore.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jchromb.2010.07.015DOI Listing
September 2010

AZD6244 enhances the anti-tumor activity of sorafenib in ectopic and orthotopic models of human hepatocellular carcinoma (HCC).

J Hepatol 2010 Jan 28;52(1):79-87. Epub 2009 Oct 28.

Laboratory of Molecular Endocrinology, Division of Molecular and Cellular Research, Humphrey Oei Institute of Cancer Research, National Cancer Centre, 11 Hospital Drive, Singapore 169610, Singapore.

View Article

Download full-text PDF

Source
http://linkinghub.elsevier.com/retrieve/pii/S016882780900654
Publisher Site
http://dx.doi.org/10.1016/j.jhep.2009.10.008DOI Listing
January 2010