Bonnie Blomberg

Bonnie Blomberg

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Bonnie Blomberg

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Immunophenotyping of Human B Lymphocytes in Blood and in Adipose Tissue.

Methods Mol Biol 2019 ;2032:115-127

Department of Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, FL, USA.

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http://dx.doi.org/10.1007/978-1-4939-9650-6_7DOI Listing
April 2020

The Impact of Obesity and Metabolic Syndrome on Vaccination Success.

Interdiscip Top Gerontol Geriatr 2020 9;43:86-97. Epub 2020 Apr 9.

Department of Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, Florida, USA.

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http://dx.doi.org/10.1159/000504440DOI Listing
April 2020

Metabolic requirements of human pro-inflammatory B cells in aging and obesity.

PLoS One 2019 9;14(7):e0219545. Epub 2019 Jul 9.

Department of Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, FL, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0219545PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6615614PMC
March 2020

Leptin induces immunosenescence in human B cells.

Cell Immunol 2020 Feb 16;348:103994. Epub 2019 Oct 16.

Department of Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, FL, USA; Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL, USA.

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http://dx.doi.org/10.1016/j.cellimm.2019.103994DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7002206PMC
February 2020

Impaired B Cell Function in Mice Lacking Perforin-2.

Front Immunol 2020 27;11:328. Epub 2020 Feb 27.

Department of Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, FL, United States.

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http://dx.doi.org/10.3389/fimmu.2020.00328DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7057857PMC
February 2020

Identification and Characterization of Adipose Tissue-Derived Human Antibodies With "Anti-self" Specificity.

Front Immunol 2020 28;11:392. Epub 2020 Feb 28.

Department of Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, FL, United States.

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http://dx.doi.org/10.3389/fimmu.2020.00392DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7058997PMC
February 2020

Adipose Tissue: A Tertiary Lymphoid Organ: Does It Change with Age?

Gerontology 2020 14;66(2):114-121. Epub 2019 Aug 14.

Department of Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, Florida, USA.

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http://dx.doi.org/10.1159/000502036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7018534PMC
August 2019

Secretion of autoimmune antibodies in the human subcutaneous adipose tissue.

PLoS One 2018 16;13(5):e0197472. Epub 2018 May 16.

Department of Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, FL, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0197472PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5955545PMC
November 2018

Differential psychological effects of cognitive-behavioral stress management among breast cancer patients with high and low initial cancer-specific distress.

J Psychosom Res 2018 10 23;113:52-57. Epub 2018 Jul 23.

Department of Psychology, University of Miami, Coral Gables, FL, United States; Sylvester Cancer Center, University of Miami, Miller School of Medicine, Miami, FL, United States; Department of Psychiatry and Behavioral Sciences University of Miami, Miller School of Medicine, Miami, FL, United States. Electronic address:

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http://dx.doi.org/10.1016/j.jpsychores.2018.07.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6130907PMC
October 2018

B Lymphocytes in Rheumatoid Arthritis and the Effects of Anti-TNF-α Agents on B Lymphocytes: A Review of the Literature.

Clin Ther 2018 06 23;40(6):1034-1045. Epub 2018 May 23.

Department of Microbiology and Immunology, Miller School of Medicine, University of Miami, Miami, Florida.

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http://dx.doi.org/10.1016/j.clinthera.2018.04.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6792291PMC
June 2018

"Aging and immunity" symposium: Meeting report.

Exp Gerontol 2018 05 26;105:1-3. Epub 2017 Dec 26.

National Institute of Health, Bethesda, MD, United States; National Institutes of Allergy and Infectious Diseases, Bethesda, MD, United States.

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https://linkinghub.elsevier.com/retrieve/pii/S05315565173086
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http://dx.doi.org/10.1016/j.exger.2017.12.004DOI Listing
May 2018

Inflammatory immune cells may impair the preBCR checkpoint, reduce new B cell production, and alter the antibody repertoire in old age.

Exp Gerontol 2018 05 7;105:87-93. Epub 2018 Feb 7.

Department of Microbiology & Immunology, University of Miami Miller School of Medicine, Miami, FL 33324, United States.

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http://dx.doi.org/10.1016/j.exger.2018.01.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5869160PMC
May 2018

Aging, Obesity, and Inflammatory Age-Related Diseases.

Front Immunol 2017 7;8:1745. Epub 2017 Dec 7.

Dipartimento di Medicina e Scienze dell'Invecchiamento, Università degli Studi 'G. d'Annunzio' Chieti-Pescara, Chieti, Italy.

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http://dx.doi.org/10.3389/fimmu.2017.01745DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5725402PMC
December 2017

Aging effects on T-bet expression in human B cell subsets.

Cell Immunol 2017 Nov 24;321:68-73. Epub 2017 Apr 24.

Department of Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, FL 33101, USA.

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http://dx.doi.org/10.1016/j.cellimm.2017.04.007DOI Listing
November 2017

Age-associated B cells (ABC) inhibit B lymphopoiesis and alter antibody repertoires in old age.

Cell Immunol 2017 Nov 26;321:61-67. Epub 2017 Apr 26.

Department of Microbiology & Immunology, University of Miami Miller School of Medicine, Miami, FL 33136, USA.

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http://dx.doi.org/10.1016/j.cellimm.2017.04.008DOI Listing
November 2017

How changes in physical activity relate to fatigue interference, mood, and quality of life during treatment for non-metastatic breast cancer.

Gen Hosp Psychiatry 2017 11 29;49:37-43. Epub 2017 May 29.

Department of Psychology, University of Miami, Coral Gables, FL 33124, United States; Sylvester Cancer Center, University of Miami Miller School of Medicine, Miami, FL 33136, United States; Department of Psychiatry and Behavioral Sciences, University of Miami Miller School of Medicine, Miami, FL 33136, United States.

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http://dx.doi.org/10.1016/j.genhosppsych.2017.05.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5681387PMC
November 2017

Small-Molecule Inhibitors of the CD40-CD40L Costimulatory Protein-Protein Interaction.

J Med Chem 2017 11 25;60(21):8906-8922. Epub 2017 Oct 25.

Diabetes Research Institute, ‡Molecular and Cellular Pharmacology, and §Microbiology and Immunology, Miller School of Medicine, University of Miami , Miami, Florida 33136, United States.

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http://dx.doi.org/10.1021/acs.jmedchem.7b01154DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823691PMC
November 2017

Adipose Tissue Inflammation Induces B Cell Inflammation and Decreases B Cell Function in Aging.

Front Immunol 2017 28;8:1003. Epub 2017 Aug 28.

Department of Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, FL, United States.

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http://dx.doi.org/10.3389/fimmu.2017.01003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5581329PMC
August 2017

Metformin improves in vivo and in vitro B cell function in individuals with obesity and Type-2 Diabetes.

Vaccine 2017 05 6;35(20):2694-2700. Epub 2017 Apr 6.

Department of Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, FL 33101, USA. Electronic address:

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http://dx.doi.org/10.1016/j.vaccine.2017.03.078DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5560851PMC
May 2017

In old BALB/c mice, bone marrow pre-B cell and surrogate light chain reduction is associated with increased B cell reactivity to phosphorylcholine, but reduced T15 idiotype dominance.

Mech Ageing Dev 2017 03 19;162:53-62. Epub 2016 Nov 19.

Department of Microbiology & Immunology, University of Miami Miller School of Medicine, Miami, FL, 33136, United States. Electronic address:

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http://dx.doi.org/10.1016/j.mad.2016.11.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5381390PMC
March 2017

Obesity induces pro-inflammatory B cells and impairs B cell function in old mice.

Mech Ageing Dev 2017 03 19;162:91-99. Epub 2017 Jan 19.

Department of Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, FL, 33101, USA.

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http://dx.doi.org/10.1016/j.mad.2017.01.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5560850PMC
March 2017

Human peripheral late/exhausted memory B cells express a senescent-associated secretory phenotype and preferentially utilize metabolic signaling pathways.

Exp Gerontol 2017 01 6;87(Pt A):113-120. Epub 2016 Dec 6.

Department of Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, FL 33101, USA.

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http://dx.doi.org/10.1016/j.exger.2016.12.001DOI Listing
January 2017

Stress management, leukocyte transcriptional changes and breast cancer recurrence in a randomized trial: An exploratory analysis.

Psychoneuroendocrinology 2016 12 24;74:269-277. Epub 2016 Sep 24.

Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, 1475 NW 12th Ave., Miami, FL 33136, USA; Dept. of Microbiology and Immunology, University of Miami Miller School of Medicine, 1600 NW 10th Ave., RMSB 3146A, Miami, FL 33136, USA.

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http://dx.doi.org/10.1016/j.psyneuen.2016.09.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5159236PMC
December 2016

Activation-Induced Cytidine Deaminase and Switched Memory B Cells as Predictors of Effective In Vivo Responses to the Influenza Vaccine.

Methods Mol Biol 2015 ;1343:107-14

Department of Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, FL, 33136, USA.

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http://dx.doi.org/10.1007/978-1-4939-2963-4_9DOI Listing
June 2016

The generation of memory B cells is maintained, but the antibody response is not, in the elderly after repeated influenza immunizations.

Vaccine 2016 05 20;34(25):2834-40. Epub 2016 Apr 20.

Department of Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, FL 33101, USA.

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http://dx.doi.org/10.1016/j.vaccine.2016.04.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4876633PMC
May 2016

Aging, cytomegalovirus (CMV) and influenza vaccine responses.

Hum Vaccin Immunother 2016 03;12(3):682-90

a Department of Microbiology and Immunology , University of Miami Miller School of Medicine , Miami , FL , USA.

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http://dx.doi.org/10.1080/21645515.2015.1105413DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4964725PMC
March 2016

Obesity decreases B cell responses in young and elderly individuals.

Obesity (Silver Spring) 2016 Mar 9;24(3):615-25. Epub 2016 Feb 9.

Department of Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, Florida, USA.

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http://dx.doi.org/10.1002/oby.21383DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4769695PMC
March 2016

Inflammaging decreases adaptive and innate immune responses in mice and humans.

Biogerontology 2016 Feb 29;17(1):7-19. Epub 2015 Apr 29.

Department of Microbiology and Immunology, University of Miami Miller School of Medicine, P.O. Box 016960 (R-138), Miami, FL, 33101, USA.

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http://dx.doi.org/10.1007/s10522-015-9578-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4626429PMC
February 2016

Postsurgical Depressive Symptoms and Proinflammatory Cytokine Elevations in Women Undergoing Primary Treatment for Breast Cancer.

Psychosom Med 2016 Jan;78(1):26-37

From the Department of Psychology, University of Miami (Bouchard, Antoni, Gudenkauf, Jutagir, Carver), Miami, Florida; Departments of Psychiatry Behavioral Sciences (Antoni, Lechner) and Microbiology Immunology (Blomberg, Diaz), Sylvester Comprehensive Cancer Center (Antoni, Lechner, Carver, Blomberg, Diaz), University of Miami Miller School of Medicine, Miami, Florida; Department of Psychiatry, Massachusetts General Hospital (Stagl), Boston, Massachusetts; Global Medical Affairs, Celgene Corporation (Glück), Summit, New Jersey; and Baptist Health Breast Center (Derhagopian), Miami, Florida.

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http://dx.doi.org/10.1097/PSY.0000000000000261DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4696897PMC
January 2016

B Cell-Specific Biomarkers for Optimal Antibody Responses to Influenza Vaccination and Molecular Pathways That Reduce B Cell Function with Aging.

Crit Rev Immunol 2016 ;36(6):523-537

Department of Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, FL 33101, USA.

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http://dx.doi.org/10.1615/CritRevImmunol.2017020113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5921867PMC
January 2016

Systems Analysis of Immunity to Influenza Vaccination across Multiple Years and in Diverse Populations Reveals Shared Molecular Signatures.

Immunity 2015 Dec;43(6):1186-98

Department of Pathology, School of Medicine, Emory University, 1648 Pierce Drive NE, Atlanta, GA 30307, USA; Emory Vaccine Center, Yerkes National Primate Research Center, 954 Gatewood Road, Atlanta, GA 30329, USA. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2015.11.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4859820PMC
December 2015

A randomized controlled trial of cognitive-behavioral stress management in breast cancer: survival and recurrence at 11-year follow-up.

Breast Cancer Res Treat 2015 Nov 30;154(2):319-28. Epub 2015 Oct 30.

Department of Psychiatry and Behavioral Sciences, University of Miami Miller School of Medicine, 1120 N.W. 14th Street, Miami, FL, 33136, USA.

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http://dx.doi.org/10.1007/s10549-015-3626-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5752103PMC
November 2015

MicroRNAs miR-155 and miR-16 Decrease AID and E47 in B Cells from Elderly Individuals.

J Immunol 2015 Sep 29;195(5):2134-40. Epub 2015 Jul 29.

Department of Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, FL 33101.

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http://dx.doi.org/10.4049/jimmunol.1500520DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4546853PMC
September 2015

Cytomegalovirus (CMV) seropositivity decreases B cell responses to the influenza vaccine.

Vaccine 2015 Mar 7;33(12):1433-9. Epub 2015 Feb 7.

Department of Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, FL 33101, USA.

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http://dx.doi.org/10.1016/j.vaccine.2015.01.071DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4352374PMC
March 2015

Sleep quality and fatigue after a stress management intervention for women with early-stage breast cancer in southern Florida.

Int J Behav Med 2014 Dec;21(6):971-81

Department of Psychiatry and Human Behavior, Warren Alpert Medical School of Brown University, Providence, RI, USA, and The Miriam Hospital, Providence, RI, USA,

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http://dx.doi.org/10.1007/s12529-013-9374-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4631117PMC
December 2014

B cell function and influenza vaccine responses in healthy aging and disease.

Curr Opin Immunol 2014 Aug 14;29:112-8. Epub 2014 Jun 14.

University of Miami Miller School of Medicine, Miami, FL 33136, USA. Electronic address:

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http://dx.doi.org/10.1016/j.coi.2014.05.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4331104PMC
August 2014

High TNF-α levels in resting B cells negatively correlate with their response.

Exp Gerontol 2014 Jun 15;54:116-22. Epub 2014 Jan 15.

Department of Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, FL 33101, USA.

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http://dx.doi.org/10.1016/j.exger.2014.01.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3989457PMC
June 2014

Age effects on mouse and human B cells.

Immunol Res 2013 Dec;57(1-3):354-60

Department of Microbiology and Immunology, University of Miami Miller School of Medicine, RMSB #3146A, P.O. Box 016960 (R-138), Miami, FL, 33101, USA,

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http://dx.doi.org/10.1007/s12026-013-8440-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5673119PMC
December 2013

Immune senescence: new insights into defects but continued mystery of root causes.

Curr Opin Immunol 2013 Aug 17;25(4):495-7. Epub 2013 Aug 17.

Department of Pathology, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655, USA. Electronic address:

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http://dx.doi.org/10.1016/j.coi.2013.08.001DOI Listing
August 2013

Age-associated alterations in γδ T-cells are present predominantly in individuals infected with Cytomegalovirus.

Immun Ageing 2013 Jul 3;10(1):26. Epub 2013 Jul 3.

Department of Internal Medicine II, Centre for Medical Research, University of Tübingen, Tübingen, Germany.

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http://dx.doi.org/10.1186/1742-4933-10-26DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3703274PMC
July 2013

In senescence, age-associated B cells secrete TNFα and inhibit survival of B-cell precursors.

Aging Cell 2013 Apr;12(2):303-11

Department of Microbiology & Immunology, University of Miami Miller School of Medicine, Miami, FL 33136, USA.

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http://dx.doi.org/10.1111/acel.12055DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3716274PMC
April 2013

Effects of age on H1N1-specific serum IgG1 and IgG3 levels evaluated during the 2011-2012 influenza vaccine season.

Immun Ageing 2013 Apr 22;10(1):14. Epub 2013 Apr 22.

Department of Microbiology and Immunology, University of Miami Miller School of Medicine, P,O, Box 016960 (R-138), Miami, FL 33101, USA.

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http://dx.doi.org/10.1186/1742-4933-10-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3639840PMC
April 2013

AID in aging and autoimmune diseases.

Autoimmunity 2013 Mar;46(2):168-75

Department of Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, FL 016960, USA.

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http://dx.doi.org/10.3109/08916934.2012.750300DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4710515PMC
March 2013

Comments on the evaluation of lymphocyte levels in a random sample of 218 elderly individuals from São Paulo city.

Rev Bras Hematol Hemoter 2011 ;33(5):333-4

Department of Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, FL, USA.

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http://dx.doi.org/10.5581/1516-8484.20110093DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3415782PMC
October 2012

AID activity in B cells strongly correlates with polyclonal antibody affinity maturation in-vivo following pandemic 2009-H1N1 vaccination in humans.

PLoS Pathog 2012 Sep 13;8(9):e1002920. Epub 2012 Sep 13.

Division of Viral Products, Center for Biologics Evaluation and Research (CBER), Food and Drug Administration (FDA), Bethesda, Maryland, USA.

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http://dx.doi.org/10.1371/journal.ppat.1002920DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3441753PMC
September 2012

Unique biomarkers for B-cell function predict the serum response to pandemic H1N1 influenza vaccine.

Int Immunol 2012 Mar 25;24(3):175-82. Epub 2012 Jan 25.

Department of Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, FL 33101, USA.

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http://dx.doi.org/10.1093/intimm/dxr123DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3621378PMC
March 2012

Cognitive-behavioral stress management reverses anxiety-related leukocyte transcriptional dynamics.

Biol Psychiatry 2012 Feb 16;71(4):366-72. Epub 2011 Nov 16.

Department of Psychology, University of Miami, Coral Gables, 5665 Ponce DeLeon Boulevard, Coral Gables, FL 33124-0751, USA.

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http://dx.doi.org/10.1016/j.biopsych.2011.10.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3264698PMC
February 2012

A molecular mechanism for TNF-α-mediated downregulation of B cell responses.

J Immunol 2012 Jan 23;188(1):279-86. Epub 2011 Nov 23.

Department of Microbiology and Immunology, University of Miami, Miami, FL 33101, USA.

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http://dx.doi.org/10.4049/jimmunol.1003964DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3700394PMC
January 2012

Peptide-conjugated PAMAM dendrimer as a universal DNA vaccine platform to target antigen-presenting cells.

Cancer Res 2011 Dec 10;71(24):7452-62. Epub 2011 Oct 10.

Department of Microbiology and Immunology, Sylvester Cancer Center, Miller School of Medicine, University of Miami, Miami, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-11-1766DOI Listing
December 2011

Aging impairs murine B cell differentiation and function in primary and secondary lymphoid tissues.

Aging Dis 2011 Oct 28;2(5):361-73. Epub 2011 Oct 28.

Department of Microbiology and Immunology, University of Miami Miller, School of Medicine, Miami, FL, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3295082PMC
October 2011

Age effects on B cells and humoral immunity in humans.

Ageing Res Rev 2011 Jul 20;10(3):330-5. Epub 2010 Aug 20.

Department of Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, FL 33101, USA.

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http://dx.doi.org/10.1016/j.arr.2010.08.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3040253PMC
July 2011

Aging affects human B cell responses.

J Clin Immunol 2011 Jun 12;31(3):430-5. Epub 2011 Feb 12.

Department of Microbiology and Immunology, University of Miami Miller School of Medicine, RMSB 3146A, P.O. Box 016960(R-138), Miami, FL 33101, USA.

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http://dx.doi.org/10.1007/s10875-010-9501-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5560853PMC
June 2011

E47 retroviral rescue of intrinsic B-cell defects in senescent mice.

Aging Cell 2011 Apr 25;10(2):327-37. Epub 2011 Feb 25.

Department of Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, FL 33101, USA.

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http://dx.doi.org/10.1111/j.1474-9726.2011.00673.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4710514PMC
April 2011

Intrinsic defects in B cell response to seasonal influenza vaccination in elderly humans.

Vaccine 2010 Nov 23;28(51):8077-84. Epub 2010 Oct 23.

Department of Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, FL 33101, USA.

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http://dx.doi.org/10.1016/j.vaccine.2010.10.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3223387PMC
November 2010

Protein phosphatase 2A (PP2A) is increased in old murine B cells and mediates p38 MAPK/tristetraprolin dephosphorylation and E47 mRNA instability.

Mech Ageing Dev 2010 May 26;131(5):306-14. Epub 2010 Feb 26.

Department of Microbiology and Immunology, University of Miami Miller School of Medicine, P.O. Box 016960 (R-138), Miami, FL 33101, USA.

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http://dx.doi.org/10.1016/j.mad.2010.02.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3223388PMC
May 2010

Psychosocial adaptation and cellular immunity in breast cancer patients in the weeks after surgery: An exploratory study.

J Psychosom Res 2009 Nov 24;67(5):369-76. Epub 2009 Sep 24.

Department of Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, FL, USA.

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http://dx.doi.org/10.1016/j.jpsychores.2009.05.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2764537PMC
November 2009

Effects of aging on B cell function.

Curr Opin Immunol 2009 Aug 14;21(4):425-30. Epub 2009 Jul 14.

Department of Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, FL 33101, USA.

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http://dx.doi.org/10.1016/j.coi.2009.06.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2853364PMC
August 2009

B cells and aging: molecules and mechanisms.

Trends Immunol 2009 Jul 18;30(7):313-8. Epub 2009 Jun 18.

Department of Pathology and Laboratory Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA 19104-6082, USA.

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http://dx.doi.org/10.1016/j.it.2009.04.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2766868PMC
July 2009

NK cells in the CD19- B220+ bone marrow fraction are increased in senescence and reduce E2A and surrogate light chain proteins in B cell precursors.

Mech Ageing Dev 2009 Jun 24;130(6):384-92. Epub 2009 Mar 24.

Department of Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, FL 33101, USA.

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http://dx.doi.org/10.1016/j.mad.2009.03.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2743292PMC
June 2009

Old mice retain bone marrow B1 progenitors, but lose B2 precursors, and exhibit altered immature B cell phenotype and light chain usage.

Mech Ageing Dev 2009 Jun 9;130(6):401-8. Epub 2009 Apr 9.

Department of Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, FL 33101, USA.

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http://dx.doi.org/10.1016/j.mad.2009.04.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2734388PMC
June 2009

Effects of fenbendazole on the murine humoral immune system.

J Am Assoc Lab Anim Sci 2009 May;48(3):251-7

Department of Microbiology, University of Miami Miller School of Medicine, Miami, Florida, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2696826PMC
May 2009

Evaluation of the tolerogenic effects of donor bone marrow cells using a severe combined immunodeficient mouse-human islet transplant model.

Hum Immunol 2008 Oct 12;69(10):605-13. Epub 2008 Aug 12.

Department of Surgery, Transplant Laboratories, Northwestern University, Chicago, IL, USA.

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http://dx.doi.org/10.1016/j.humimm.2008.07.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4094136PMC
October 2008

Aging down-regulates the transcription factor E2A, activation-induced cytidine deaminase, and Ig class switch in human B cells.

J Immunol 2008 Apr;180(8):5283-90

Department of Microbiology and Immunology, University of Miami, Miller School of Medicine, Miami, FL 33101, USA.

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http://dx.doi.org/10.4049/jimmunol.180.8.5283DOI Listing
April 2008

Mechanisms for decreased function of B cells in aged mice and humans.

J Immunol 2008 Mar;180(5):2741-6

Department of Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, FL 33101, USA.

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http://dx.doi.org/10.4049/jimmunol.180.5.2741DOI Listing
March 2008

Tristetraprolin, a negative regulator of mRNA stability, is increased in old B cells and is involved in the degradation of E47 mRNA.

J Immunol 2007 Jul;179(2):918-27

Department of Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, FL 33101, USA.

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http://dx.doi.org/10.4049/jimmunol.179.2.918DOI Listing
July 2007

Induction of auto-reactive regulatory T cells by stimulation with immature autologous dendritic cells.

Immunol Invest 2007 ;36(2):213-32

The Lillian Jean Kaplan Renal Transplant Center of the Division of Transplantation of the Department of Surgery, University of Miami, Leonard M. Miller School of Medicine, Miami, Florida 33101, USA.

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http://dx.doi.org/10.1080/08820130601015775DOI Listing
June 2007

Aging murine B cells have decreased class switch induced by anti-CD40 or BAFF.

Exp Gerontol 2007 Mar 25;42(3):192-203. Epub 2006 Oct 25.

Department of Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, FL 33101, USA.

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http://dx.doi.org/10.1016/j.exger.2006.09.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1876723PMC
March 2007

Accelerated Notch-dependent degradation of E47 proteins in aged B cell precursors is associated with increased ERK MAPK activation.

J Immunol 2007 Mar;178(6):3521-9

Department of Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, FL 33101, USA.

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http://dx.doi.org/10.4049/jimmunol.178.6.3521DOI Listing
March 2007

RNA stability of the E2A-encoded transcription factor E47 is lower in splenic activated B cells from aged mice.

J Immunol 2005 Nov;175(10):6633-44

Department of Microbiology and Immunology, University of Miami Miller School of Medicine, Miami, FL 33101, USA.

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http://dx.doi.org/10.4049/jimmunol.175.10.6633DOI Listing
November 2005

Deficient B lymphopoiesis in murine senescence: potential roles for dysregulation of E2A, Pax-5, and STAT5.

Semin Immunol 2005 Oct;17(5):330-6

Department of Microbiology and Immunology, University of Miami Leonard M. Miller School of Medicine, P.O. Box 016960 (R-138), Miami, FL 33101, USA.

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http://dx.doi.org/10.1016/j.smim.2005.05.011DOI Listing
October 2005

Humoral immune response and B-cell functions including immunoglobulin class switch are downregulated in aged mice and humans.

Semin Immunol 2005 Oct;17(5):378-84

Department of Microbiology and Immunology, University of Miami Miller School of Medicine, P.O. Box 016960 (R-138), Miami, FL 33101, USA.

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http://dx.doi.org/10.1016/j.smim.2005.05.005DOI Listing
October 2005

Effect of age on the immunoglobulin class switch.

Crit Rev Immunol 2004 ;24(5):297-320

Department of Microbiology and Immunology, University of Miami School of Medicine, P.O. Box 016960 (R-138), Miami, FL 33101, USA.

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http://dx.doi.org/10.1615/critrevimmunol.v24.i5.10DOI Listing
June 2005

B cells, E2A, and aging.

Immunol Rev 2005 Jun;205:30-47

Department of Microbiology and Immunology, University of Miami Miller School of Medicine, FL 33101, USA.

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http://dx.doi.org/10.1111/j.0105-2896.2005.00268.xDOI Listing
June 2005

Decreased E47 in senescent B cell precursors is stage specific and regulated posttranslationally by protein turnover.

J Immunol 2004 Jul;173(2):818-27

Department of Microbiology and Immunology, University of Miami School of Medicine, Miami, FL 33101, USA.

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http://dx.doi.org/10.4049/jimmunol.173.2.818DOI Listing
July 2004

Age-related differences in the E2A-encoded transcription factor E47 in bone marrow-derived B cell precursors and in splenic B cells.

Exp Gerontol 2004 Apr;39(4):481-9

Department of Microbiology and Immunology, RMSB #3146A, University of Miami School of Medicine, 1600 NW 10th Ave, Miami, FL 33136, USA.

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http://dx.doi.org/10.1016/j.exger.2003.09.027DOI Listing
April 2004

Reduced Ig class switch in aged mice correlates with decreased E47 and activation-induced cytidine deaminase.

J Immunol 2004 Feb;172(4):2155-62

Department of Microbiology and Immunology, University of Miami School of Medicine, Miami, FL 33136, USA.

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http://dx.doi.org/10.4049/jimmunol.172.4.2155DOI Listing
February 2004

Effects of aging on DNA-binding activity of the E47 transcription factor in splenic B cells.

Mech Ageing Dev 2004 Feb;125(2):111-2

Department of Microbiology and Immunology, University of Miami School of Medicine, 1600 N.W. 10th Ave, Miami, FL 33136, USA.

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http://dx.doi.org/10.1016/j.mad.2003.11.004DOI Listing
February 2004