Bogdan Budnik

Bogdan Budnik

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Bogdan Budnik

Bogdan Budnik

Publications by authors named "Bogdan Budnik"

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Abnormal Striatal Development Underlies the Early Onset of Behavioral Deficits in Shank3B Mice.

Cell Rep 2019 Nov;29(7):2016-2027.e4

Howard Hughes Medical Institute, Department of Neurobiology, Harvard Medical School, 220 Longwood Ave., Boston, MA 02115, USA.

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http://dx.doi.org/10.1016/j.celrep.2019.10.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889826PMC
November 2019

6-Phosphogluconate Dehydrogenase Links Cytosolic Carbohydrate Metabolism to Protein Secretion via Modulation of Glutathione Levels.

Cell Chem Biol 2019 Sep 13;26(9):1306-1314.e5. Epub 2019 Jun 13.

Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA; Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA 02138, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chembiol.2019.05.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754299PMC
September 2019

Molecular physiology of chemical defenses in a poison frog.

J Exp Biol 2019 Jun 20;222(Pt 12). Epub 2019 Jun 20.

Department of Biology, Stanford University, Stanford, CA 94305, USA

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http://dx.doi.org/10.1242/jeb.204149DOI Listing
June 2019

Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression.

J Biol Chem 2019 05 22;294(22):8760-8772. Epub 2019 Apr 22.

From the Departments of Oncology and Biochemistry & Molecular Biology, Georgetown University School of Medicine, Washington, D. C. 20057,

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http://dx.doi.org/10.1074/jbc.RA119.007832DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6552432PMC
May 2019

Quantifying Homologous Proteins and Proteoforms.

Mol Cell Proteomics 2019 01 3;18(1):162-168. Epub 2018 Oct 3.

§Department of Bioengineering, Northeastern University, Boston, MA 02115;

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http://www.mcponline.org/lookup/doi/10.1074/mcp.TIR118.00094
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http://dx.doi.org/10.1074/mcp.TIR118.000947DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6317479PMC
January 2019

Dynamic disulfide exchange in a crystallin protein in the human eye lens promotes cataract-associated aggregation.

J Biol Chem 2018 11 21;293(46):17997-18009. Epub 2018 Sep 21.

From the Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts 02138,

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http://www.jbc.org/lookup/doi/10.1074/jbc.RA118.004551
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http://dx.doi.org/10.1074/jbc.RA118.004551DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240864PMC
November 2018

A linked organ-on-chip model of the human neurovascular unit reveals the metabolic coupling of endothelial and neuronal cells.

Nat Biotechnol 2018 10 20;36(9):865-874. Epub 2018 Aug 20.

Disease Biophysics Group, Harvard John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, Massachusetts, USA.

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http://dx.doi.org/10.1038/nbt.4226DOI Listing
October 2018

SCoPE-MS: mass spectrometry of single mammalian cells quantifies proteome heterogeneity during cell differentiation.

Genome Biol 2018 10 22;19(1):161. Epub 2018 Oct 22.

Department of Biology, Northeastern University, Boston, MA, 02115, USA.

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http://dx.doi.org/10.1186/s13059-018-1547-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6196420PMC
October 2018

Neurons derived from different brain regions are inherently different in vitro: a novel multiregional brain-on-a-chip.

J Neurophysiol 2017 03 28;117(3):1320-1341. Epub 2016 Dec 28.

Disease Biophysics Group, Wyss Institute for Biologically Inspired Engineering, John A. Paulson School of Engineering and Applied Sciences, Harvard University, Cambridge, Massachusetts; and

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http://www.physiology.org/doi/10.1152/jn.00575.2016
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http://dx.doi.org/10.1152/jn.00575.2016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5350271PMC
March 2017

A human microprotein that interacts with the mRNA decapping complex.

Nat Chem Biol 2017 02 5;13(2):174-180. Epub 2016 Dec 5.

Department of Chemistry and Chemical Biology, Chemical Biology Institute, Yale University, New Haven, Connecticut, USA.

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http://dx.doi.org/10.1038/nchembio.2249DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5247292PMC
February 2017

Differential Stoichiometry among Core Ribosomal Proteins.

Cell Rep 2015 Nov 22;13(5):865-73. Epub 2015 Oct 22.

Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences and University Medical Center Utrecht, Uppsalalaan 8, 3584 CT Utrecht, the Netherlands.

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http://dx.doi.org/10.1016/j.celrep.2015.09.056DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4644233PMC
November 2015

Systems-level response to point mutations in a core metabolic enzyme modulates genotype-phenotype relationship.

Cell Rep 2015 Apr 16;11(4):645-56. Epub 2015 Apr 16.

Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, MA 02138, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2015.03.051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4416983PMC
April 2015

Quantifying condition-dependent intracellular protein levels enables high-precision fitness estimates.

PLoS One 2013 25;8(9):e75320. Epub 2013 Sep 25.

Center for Genomics and Systems Biology, Department of Biology, New York University, New York, New York, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0075320PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3783400PMC
July 2014

Constant growth rate can be supported by decreasing energy flux and increasing aerobic glycolysis.

Cell Rep 2014 May 24;7(3):705-14. Epub 2014 Apr 24.

Departments of Physics and Biology and Koch Institute for Integrative Cancer Research, Massachusetts Institute of Technology, Cambridge, MA 02139, USA; Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences and University Medical Center Utrecht, Uppsalalaan 8, 3584 CT Utrecht, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2014.03.057DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4049626PMC
May 2014

A human short open reading frame (sORF)-encoded polypeptide that stimulates DNA end joining.

J Biol Chem 2014 Apr 7;289(16):10950-7. Epub 2014 Mar 7.

From the Department of Chemistry and Chemical Biology and.

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http://dx.doi.org/10.1074/jbc.C113.533968DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4036235PMC
April 2014

Discovery of human sORF-encoded polypeptides (SEPs) in cell lines and tissue.

J Proteome Res 2014 Mar 14;13(3):1757-65. Epub 2014 Feb 14.

Department of Chemistry and Chemical Biology, Harvard University , 12 Oxford Street, Cambridge, Massachusetts 02138, United States.

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http://dx.doi.org/10.1021/pr401280wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3993966PMC
March 2014

Peptidomic discovery of short open reading frame-encoded peptides in human cells.

Nat Chem Biol 2013 Jan 18;9(1):59-64. Epub 2012 Nov 18.

Department of Chemistry and Chemical Biology, Harvard University, Cambridge, Massachusetts, USA.

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http://dx.doi.org/10.1038/nchembio.1120DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3625679PMC
January 2013

Tunable signal processing through modular control of transcription factor translocation.

Science 2013 Jan;339(6118):460-4

Harvard University Faculty of Arts and Sciences Center for Systems Biology, Cambridge, MA 02138, USA.

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http://dx.doi.org/10.1126/science.1227299DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3746486PMC
January 2013

Misfolded proteins impose a dosage-dependent fitness cost and trigger a cytosolic unfolded protein response in yeast.

Proc Natl Acad Sci U S A 2011 Jan 27;108(2):680-5. Epub 2010 Dec 27.

Department of Organismic and Evolutionary Biology, Harvard University, Cambridge, MA 02138, USA.

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http://dx.doi.org/10.1073/pnas.1017570108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3021021PMC
January 2011

Temporal variations of the postnatal rat urinary proteome as a reflection of systemic maturation.

Proteomics 2008 Mar;8(5):1097-112

Department of Urology, Harvard Medical School, Urological Diseases Research Center, Children's Hospital Boston, Boston, MA 02115, USA.

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http://dx.doi.org/10.1002/pmic.200700701DOI Listing
March 2008

Global methods for protein glycosylation analysis by mass spectrometry.

Biochim Biophys Acta 2006 Dec 18;1764(12):1870-80. Epub 2006 Oct 18.

Department of Pathology, Children's Hospital Boston and Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1016/j.bbapap.2006.10.005DOI Listing
December 2006

Long-lived electron capture dissociation product ions experience radical migration via hydrogen abstraction.

J Am Soc Mass Spectrom 2006 Apr 28;17(4):576-585. Epub 2006 Feb 28.

Mass Spectrometry Resource, Department of Biochemistry, Boston University School of Medicine, 670 Albany St., Rm. 507, 02118, Boston, MA, USA.

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http://dx.doi.org/10.1016/j.jasms.2005.12.015DOI Listing
April 2006

A new hybrid electrospray Fourier transform mass spectrometer: design and performance characteristics.

Rapid Commun Mass Spectrom 2006 ;20(2):259-66

Mass Spectrometry Resource, Department of Biochemistry, Boston University School of Medicine, 715 Albany St. R806, Boston, MA 02118-2526, USA.

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http://dx.doi.org/10.1002/rcm.2307DOI Listing
February 2006

Characterization of a new qQq-FTICR mass spectrometer for post-translational modification analysis and top-down tandem mass spectrometry of whole proteins.

J Am Soc Mass Spectrom 2005 Dec 2;16(12):1985-99. Epub 2005 Nov 2.

Mass Spectrometry Resource, Department of Biochemistry, Boston University School of Medicine, MA 02115, USA.

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http://dx.doi.org/10.1016/j.jasms.2005.08.008DOI Listing
December 2005

Coupling thin-layer chromatography with vibrational cooling matrix-assisted laser desorption/ionization Fourier transform mass spectrometry for the analysis of ganglioside mixtures.

Anal Chem 2004 Nov;76(21):6484-91

Mass Spectrometry Resource, Cardiovascular Proteomics Center, and Department of Biochemistry, Boston University School of Medicine, 715 Albany Street R-806, Boston, Massachusetts 02118-2526, USA.

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http://dx.doi.org/10.1021/ac0491556DOI Listing
November 2004

Electron capture dissociation distinguishes a single D-amino acid in a protein and probes the tertiary structure.

J Am Soc Mass Spectrom 2004 Jul;15(7):1087-98

Laboratory for Biological and Medical Mass Spectrometry, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.1016/j.jasms.2004.04.026DOI Listing
July 2004

Isolation of a library of aromadendranes from Landolphia dulcis and its characterization using the VolSurf approach.

J Nat Prod 2004 May;67(5):799-805

Department of Medicinal Chemistry, The Danish University of Pharmaceutical Sciences, Universitetsparken 2, DK-2100 Copenhagen, Denmark.

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http://dx.doi.org/10.1021/np0340450DOI Listing
May 2004

A high pressure matrix-assisted laser desorption ion source for Fourier transform mass spectrometry designed to accommodate large targets with diverse surfaces.

J Am Soc Mass Spectrom 2004 Jan;15(1):128-32

Department of Biochemistry, Boston University School of Medicine, Boston, Massachusetts 02118, USA.

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http://dx.doi.org/10.1016/j.jasms.2003.10.005DOI Listing
January 2004

Attomole peptide analysis by high-pressure matrix-assisted laser desorption/ionization Fourier transform mass spectrometry.

Anal Chem 2003 Dec;75(23):6449-54

Mass Spectrometry Resource, Boston University School of Medicine, 715 Albany Street, Boston, Massachusetts 02118-2526, USA.

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http://dx.doi.org/10.1021/ac034938xDOI Listing
December 2003

Electron capture dissociation of weakly bound polypeptide polycationic complexes.

Rapid Commun Mass Spectrom 2002 ;16(24):2260-5

Department of Chemistry, University of Southern Denmark, Odense, Denmark.

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http://dx.doi.org/10.1002/rcm.853DOI Listing
February 2003

Ionization energies of multiply protonated polypeptides obtained by tandem ionization in Fourier transform mass spectrometers.

J Mass Spectrom 2002 Nov;37(11):1141-4

Department of Chemistry, University of Southern Denmark, Odense, Denmark.

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http://doi.wiley.com/10.1002/jms.376
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http://dx.doi.org/10.1002/jms.376DOI Listing
November 2002

In vitro cytotoxic activity of phenanthroindolizidine alkaloids from Cynanchum vincetoxicum and Tylophora tanakae against drug-sensitive and multidrug-resistant cancer cells.

J Nat Prod 2002 Sep;65(9):1299-302

Department of Medicinal Chemistry, Royal Danish School of Pharmacy, Universitetsparken 2, DK-2100 Copenhagen, Denmark.

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http://dx.doi.org/10.1021/np0106384DOI Listing
September 2002