Bo L Chawes

Bo L Chawes

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Bo L Chawes

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Fish-oil supplementation in pregnancy, child metabolomics and asthma risk.

EBioMedicine 2019 Aug 6;46:399-410. Epub 2019 Aug 6.

COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2019.07.057DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6712349PMC
August 2019

Fish oil supplementation during pregnancy is protective against asthma/wheeze in offspring.

J Allergy Clin Immunol Pract 2019 Jun 19. Epub 2019 Jun 19.

Channing Division of Network Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass. Electronic address:

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http://dx.doi.org/10.1016/j.jaip.2019.05.054DOI Listing
June 2019

Multiple Breath Washout for Diagnosing Asthma and Persistent Wheeze in Young Children.

Ann Am Thorac Soc 2019 May;16(5):599-605

Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1513/AnnalsATS.201807-503OCDOI Listing
May 2019

Maternal and fetal genetic effects on birth weight and their relevance to cardio-metabolic risk factors.

Authors:
Nicole M Warrington Robin N Beaumont Momoko Horikoshi Felix R Day Øyvind Helgeland Charles Laurin Jonas Bacelis Shouneng Peng Ke Hao Bjarke Feenstra Andrew R Wood Anubha Mahajan Jessica Tyrrell Neil R Robertson N William Rayner Zhen Qiao Gunn-Helen Moen Marc Vaudel Carmen J Marsit Jia Chen Michael Nodzenski Theresia M Schnurr Mohammad H Zafarmand Jonathan P Bradfield Niels Grarup Marjolein N Kooijman Ruifang Li-Gao Frank Geller Tarunveer S Ahluwalia Lavinia Paternoster Rico Rueedi Ville Huikari Jouke-Jan Hottenga Leo-Pekka Lyytikäinen Alana Cavadino Sarah Metrustry Diana L Cousminer Ying Wu Elisabeth Thiering Carol A Wang Christian T Have Natalia Vilor-Tejedor Peter K Joshi Jodie N Painter Ioanna Ntalla Ronny Myhre Niina Pitkänen Elisabeth M van Leeuwen Raimo Joro Vasiliki Lagou Rebecca C Richmond Ana Espinosa Sheila J Barton Hazel M Inskip John W Holloway Loreto Santa-Marina Xavier Estivill Wei Ang Julie A Marsh Christoph Reichetzeder Letizia Marullo Berthold Hocher Kathryn L Lunetta Joanne M Murabito Caroline L Relton Manolis Kogevinas Leda Chatzi Catherine Allard Luigi Bouchard Marie-France Hivert Ge Zhang Louis J Muglia Jani Heikkinen Camilla S Morgen Antoine H C van Kampen Barbera D C van Schaik Frank D Mentch Claudia Langenberg Jian'an Luan Robert A Scott Jing Hua Zhao Gibran Hemani Susan M Ring Amanda J Bennett Kyle J Gaulton Juan Fernandez-Tajes Natalie R van Zuydam Carolina Medina-Gomez Hugoline G de Haan Frits R Rosendaal Zoltán Kutalik Pedro Marques-Vidal Shikta Das Gonneke Willemsen Hamdi Mbarek Martina Müller-Nurasyid Marie Standl Emil V R Appel Cilius E Fonvig Caecilie Trier Catharina E M van Beijsterveldt Mario Murcia Mariona Bustamante Sílvia Bonas-Guarch David M Hougaard Josep M Mercader Allan Linneberg Katharina E Schraut Penelope A Lind Sarah E Medland Beverley M Shields Bridget A Knight Jin-Fang Chai Kalliope Panoutsopoulou Meike Bartels Friman Sánchez Jakob Stokholm David Torrents Rebecca K Vinding Sara M Willems Mustafa Atalay Bo L Chawes Peter Kovacs Inga Prokopenko Marcus A Tuke Hanieh Yaghootkar Katherine S Ruth Samuel E Jones Po-Ru Loh Anna Murray Michael N Weedon Anke Tönjes Michael Stumvoll Kim F Michaelsen Aino-Maija Eloranta Timo A Lakka Cornelia M van Duijn Wieland Kiess Antje Körner Harri Niinikoski Katja Pahkala Olli T Raitakari Bo Jacobsson Eleftheria Zeggini George V Dedoussis Yik-Ying Teo Seang-Mei Saw Grant W Montgomery Harry Campbell James F Wilson Tanja G M Vrijkotte Martine Vrijheid Eco J C N de Geus M Geoffrey Hayes Haja N Kadarmideen Jens-Christian Holm Lawrence J Beilin Craig E Pennell Joachim Heinrich Linda S Adair Judith B Borja Karen L Mohlke Johan G Eriksson Elisabeth E Widén Andrew T Hattersley Tim D Spector Mika Kähönen Jorma S Viikari Terho Lehtimäki Dorret I Boomsma Sylvain Sebert Peter Vollenweider Thorkild I A Sørensen Hans Bisgaard Klaus Bønnelykke Jeffrey C Murray Mads Melbye Ellen A Nohr Dennis O Mook-Kanamori Fernando Rivadeneira Albert Hofman Janine F Felix Vincent W V Jaddoe Torben Hansen Charlotta Pisinger Allan A Vaag Oluf Pedersen André G Uitterlinden Marjo-Riitta Järvelin Christine Power Elina Hyppönen Denise M Scholtens William L Lowe George Davey Smith Nicholas J Timpson Andrew P Morris Nicholas J Wareham Hakon Hakonarson Struan F A Grant Timothy M Frayling Debbie A Lawlor Pål R Njølstad Stefan Johansson Ken K Ong Mark I McCarthy John R B Perry David M Evans Rachel M Freathy

Nat Genet 2019 05 1;51(5):804-814. Epub 2019 May 1.

Institute of Biomedical and Clinical Science, College of Medicine and Health, University of Exeter, Royal Devon and Exeter Hospital, Exeter, UK.

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http://dx.doi.org/10.1038/s41588-019-0403-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522365PMC
May 2019

Fish Oil Supplementation in Pregnancy Increases Gestational Age, Size for Gestational Age, and Birth Weight in Infants: A Randomized Controlled Trial.

J Nutr 2019 Apr;149(4):628-634

COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.

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https://academic.oup.com/jn/advance-article/doi/10.1093/jn/n
Publisher Site
http://dx.doi.org/10.1093/jn/nxy204DOI Listing
April 2019

High-Dose Vitamin D Supplementation During Pregnancy and Asthma in Offspring at the Age of 6 Years.

JAMA 2019 03;321(10):1003-1005

Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte University Hospital, Copenhagen, Denmark.

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http://dx.doi.org/10.1001/jama.2019.0052DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6439670PMC
March 2019

Sensitivity of multiple breath washout to detect mild-to-moderate asthma in adolescence.

J Allergy Clin Immunol Pract 2019 Jul - Aug;7(6):2052-2054.e5. Epub 2019 Jan 29.

COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1016/j.jaip.2019.01.035DOI Listing
January 2019

Effect of fish oil supplementation in pregnancy on bone, lean, and fat mass at six years: randomised clinical trial.

BMJ 2018 Sep 4;362:k3312. Epub 2018 Sep 4.

COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122120PMC
http://dx.doi.org/10.1136/bmj.k3312DOI Listing
September 2018

An Integrative Transcriptomic and Metabolomic Study of Lung Function in Children With Asthma.

Chest 2018 08 13;154(2):335-348. Epub 2018 Jun 13.

Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.1016/j.chest.2018.05.038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6689076PMC
August 2018

Cat exposure in early life decreases asthma risk from the 17q21 high-risk variant.

J Allergy Clin Immunol 2018 05 25;141(5):1598-1606. Epub 2017 Oct 25.

COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2017.07.044DOI Listing
May 2018

Publisher Correction: Maturation of the gut microbiome and risk of asthma in childhood.

Nat Commun 2018 02 13;9(1):704. Epub 2018 Feb 13.

COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Ledreborg Alle 34, 2820, Gentofte, Denmark.

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http://dx.doi.org/10.1038/s41467-018-03150-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5811596PMC
February 2018

Maturation of the gut microbiome and risk of asthma in childhood.

Nat Commun 2018 01 10;9(1):141. Epub 2018 Jan 10.

COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Ledreborg Alle 34, 2820, Gentofte, Denmark.

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http://dx.doi.org/10.1038/s41467-017-02573-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5762761PMC
January 2018

Sensitization trajectories in childhood revealed by using a cluster analysis.

J Allergy Clin Immunol 2017 Dec 25;140(6):1693-1699. Epub 2017 Mar 25.

COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark; Department of Food Science, Faculty of Science, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1016/j.jaci.2017.01.041DOI Listing
December 2017

CDHR3 gene variation and childhood bronchiolitis.

J Allergy Clin Immunol 2017 11 4;140(5):1469-1471.e7. Epub 2017 Aug 4.

COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Faculty of Health and Medical Sciences, University of Copenhagen & Danish Pediatric Asthma Center, Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.

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https://linkinghub.elsevier.com/retrieve/pii/S00916749173126
Publisher Site
http://dx.doi.org/10.1016/j.jaci.2017.06.044DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5675819PMC
November 2017

Vitamin D prenatal programming of childhood metabolomics profiles at age 3 y.

Am J Clin Nutr 2017 Oct 23;106(4):1092-1099. Epub 2017 Aug 23.

Channing Division of Network Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA; and

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http://dx.doi.org/10.3945/ajcn.117.158220DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5611786PMC
October 2017

Noninvasive Sampling of Mucosal Lining Fluid for the Quantification of In Vivo Upper Airway Immune-mediator Levels.

J Vis Exp 2017 08 7(126). Epub 2017 Aug 7.

Copenhagen Prospective Studies on Asthma in Childhood (COPSAC), Herlev and Gentofte Hospital, University of Copenhagen;

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http://dx.doi.org/10.3791/55800DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5614099PMC
August 2017

Applications of Metabolomics in the Study and Management of Preeclampsia; A Review of the Literature.

Metabolomics 2017 07 12;13(7). Epub 2017 Jun 12.

Channing Division of Network Medicine, Brigham and Women's Hospital Harvard Medical School, Boston MA 02115, USA.

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http://dx.doi.org/10.1007/s11306-017-1225-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6247796PMC
July 2017

Cesarean Delivery and Body Mass Index at 6 Months and Into Childhood.

Pediatrics 2017 Jun;139(6)

Copenhagen Prospective Studies on Asthma in Childhood, Faculty of Health and Medical Sciences, University of Copenhagen and Danish Pediatric Asthma Center, Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.

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http://dx.doi.org/10.1542/peds.2016-4066DOI Listing
June 2017

In utero exposure to 25-hydroxyvitamin D and risk of childhood asthma, wheeze, and respiratory tract infections: A meta-analysis of birth cohort studies.

J Allergy Clin Immunol 2017 May 14;139(5):1508-1517. Epub 2016 Sep 14.

Department of Epidemiology and Biostatistics, School of Public Health-Bloomington, Indiana University, Bloomington, Ind. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2016.06.065DOI Listing
May 2017

Fish Oil-Derived Fatty Acids in Pregnancy and Wheeze and Asthma in Offspring.

N Engl J Med 2016 12;375(26):2530-9

From COPSAC (Copenhagen Prospective Studies on Asthma in Childhood), Herlev and Gentofte Hospital, University of Copenhagen (H.B., J.S., B.L.C., N.H.V., E.B., A.-M.M.S., H.M.W., T.M.P., R.K.V., S.T., N.V.F., N.R.F., J.T., J.W., M.A.R., K.B.), and the Center for Fetal Programming, Statens Serum Institut (S.F.O.), Copenhagen, the Department of Pediatrics, Naestved Hospital, Naestved (J.S., E.B., T.M.P., R.K.V.), DTU Bioinformatics, Technical University of Denmark, Kongens Lyngby (A.G.P.), and Faculty of Science, Chemometrics and Analytical Technology, University of Copenhagen (M.A.R.) - all in Denmark; the Department of Kinesiology, University of Waterloo, Waterloo, ON, Canada (K.D.S.); and the Department of Nutrition, Harvard School of Public Health, Boston (S.F.O.).

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http://dx.doi.org/10.1056/NEJMoa1503734DOI Listing
December 2016

Cesarean section changes neonatal gut colonization.

J Allergy Clin Immunol 2016 09 1;138(3):881-889.e2. Epub 2016 Apr 1.

COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2016.01.028DOI Listing
September 2016

Picornavirus-Induced Airway Mucosa Immune Profile in Asymptomatic Neonates.

J Infect Dis 2016 Apr 9;213(8):1262-70. Epub 2015 Dec 9.

COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen.

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http://dx.doi.org/10.1093/infdis/jiv594DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5007587PMC
April 2016

Blood lipid levels associate with childhood asthma, airway obstruction, bronchial hyperresponsiveness, and aeroallergen sensitization.

J Allergy Clin Immunol 2016 Jan 3;137(1):68-74.e4. Epub 2015 Jul 3.

COPSAC, Copenhagen Prospective Studies on Asthma in Childhood, Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2015.05.033DOI Listing
January 2016

Cord blood 25(OH)-vitamin D deficiency and childhood asthma, allergy and eczema: the COPSAC2000 birth cohort study.

PLoS One 2014 12;9(6):e99856. Epub 2014 Jun 12.

Copenhagen Prospective Studies on Asthma in Childhood, Health Sciences, University of Copenhagen, Danish Pediatric Asthma Center, Copenhagen University Hospital, Gentofte, Denmark.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0099856PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4055727PMC
December 2015

Neonates with reduced neonatal lung function have systemic low-grade inflammation.

J Allergy Clin Immunol 2015 Jun 8;135(6):1450-6.e1. Epub 2015 Jan 8.

Copenhagen Prospective Studies on Asthma in Childhood, Health and Medical Sciences, University of Copenhagen & Danish Pediatric Asthma Center, Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2014.11.020DOI Listing
June 2015

DENND1B gene variants associate with elevated exhaled nitric oxide in healthy high-risk neonates.

Pediatr Pulmonol 2015 Feb 17;50(2):109-17. Epub 2013 Dec 17.

Copenhagen Prospective Studies on Asthma in Childhood; COPSAC, Health Sciences, University of Copenhagen, Copenhagen University Hospital, Gentofte, Ledreborg Allé 34, Gentofte, 2820, Copenhagen, Denmark.

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http://www.copsac.com/userfiles/2013_Chawes_Pediatr%20Pulm.p
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http://doi.wiley.com/10.1002/ppul.22958
Publisher Site
http://dx.doi.org/10.1002/ppul.22958DOI Listing
February 2015

The systemic exposure to inhaled beclometasone/formoterol pMDI with valved holding chamber is independent of age and body size.

Pulm Pharmacol Ther 2015 Feb 16;30:102-9. Epub 2014 Apr 16.

Copenhagen Prospective Studies on Asthma in Childhood, Health Sciences, University of Copenhagen & Danish Pediatric Asthma Center, Copenhagen University Hospital, Gentofte, Denmark.

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https://linkinghub.elsevier.com/retrieve/pii/S10945539140004
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http://dx.doi.org/10.1016/j.pupt.2014.04.003DOI Listing
February 2015

A clinical pharmacology study of fixed vs. free combination of inhaled beclometasone dipropionate and formoterol fumarate dry powder inhalers in asthmatic adolescents.

Br J Clin Pharmacol 2014 Nov;78(5):1169-71

Copenhagen Prospective Studies on Asthma in Childhood, Health Sciences, University of Copenhagen & Danish Pediatric Asthma Center, Copenhagen University Hospital, Gentofte, Denmark.

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http://dx.doi.org/10.1111/bcp.12424DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4243893PMC
November 2014

Prevalence and predictors of antibiotic administration during pregnancy and birth.

PLoS One 2013 10;8(12):e82932. Epub 2013 Dec 10.

Copenhagen Prospective Studies on Asthma in Childhood, Health Sciences, University of Copenhagen, Naestved Hospital, Naestved, Denmark ; Copenhagen Prospective Studies on Asthma in Childhood, Health Sciences, University of Copenhagen, Copenhagen University Hospital, Gentofte, Copenhagen, Denmark.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0082932PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3858309PMC
September 2014

Effect of delivery device on systemic exposure to inhaled fluticasone propionate in children with asthma.

Br J Clin Pharmacol 2014 Aug;78(2):435-7

Copenhagen Prospective Studies on Asthma in Childhood, Health Sciences, University of Copenhagen & Danish Pediatric Asthma Center, Copenhagen University Hospital, Gentofte, Denmark.

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http://dx.doi.org/10.1111/bcp.12340DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4137838PMC
August 2014

Increased risk of pneumonia and bronchiolitis after bacterial colonization of the airways as neonates.

Am J Respir Crit Care Med 2013 Nov;188(10):1246-52

1 Copenhagen Prospective Studies on Asthma in Childhood, Health Sciences, University of Copenhagen and Copenhagen University Hospital, Gentofte, Copenhagen, Denmark.

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http://dx.doi.org/10.1164/rccm.201302-0215OCDOI Listing
November 2013

Aerosol particle size does not predict pharmacokinetic determined lung dose in children.

J Clin Pharmacol 2013 May 30;53(5):517-22. Epub 2013 Mar 30.

Copenhagen Prospective Studies on Asthma in Childhood, Danish Pediatric Asthma Center, Health Sciences, University of Copenhagen, Copenhagen University Hospital, Gentofte, Copenhagen, Denmark.

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http://dx.doi.org/10.1002/jcph.74DOI Listing
May 2013

Pathogenic bacteria colonizing the airways in asymptomatic neonates stimulates topical inflammatory mediator release.

Am J Respir Crit Care Med 2013 Mar 31;187(6):589-95. Epub 2013 Jan 31.

Copenhagen Prospective Studies on Asthma in Childhood, Copenhagen University Hospital, Gentofte, Ledreborg Allé 34, Gentofte, Copenhagen, Denmark.

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http://dx.doi.org/10.1164/rccm.201207-1297OCDOI Listing
March 2013

Neonatal bronchial hyperresponsiveness precedes acute severe viral bronchiolitis in infants.

J Allergy Clin Immunol 2012 Aug 17;130(2):354-61.e3. Epub 2012 Jun 17.

Copenhagen Prospective Studies on Asthma in Childhood, Health Sciences, University of Copenhagen and Danish Pediatric Asthma Centre, Copenhagen University Hospital, Gentofte, Denmark.

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http://dx.doi.org/10.1016/j.jaci.2012.04.045DOI Listing
August 2012

[Plastic bronchitis in a ten year-old boy with Fontan circulation].

Ugeskr Laeger 2012 Jun;174(24):1674-5

BørneUngeKlinikken, Dansk BørneLungeCenter, Juliane Marie Centret, Rigshospitalet, Blegdamsvej 9, 2100 København Ø, Denmark.

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June 2012

Neonatal cytokine profile in the airway mucosal lining fluid is skewed by maternal atopy.

Am J Respir Crit Care Med 2012 Feb 10;185(3):275-80. Epub 2011 Nov 10.

Copenhagen Prospective Studies on Asthma in Childhood, Health Sciences, University of Copenhagen, Copenhagen University Hospital, Gentofte, Denmark.

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http://www.atsjournals.org/doi/abs/10.1164/rccm.201108-1471O
Publisher Site
http://dx.doi.org/10.1164/rccm.201108-1471OCDOI Listing
February 2012

Upper and lower airway pathology in young children with allergic- and non-allergic rhinitis.

Authors:
Bo L K Chawes

Dan Med Bull 2011 May;58(5):B4278

Copenhagen Prospective Studies on Asthma in Childhood, Health Sciences, University of Copenhagen & The Danish Pediatric Asthma Center, Copenhagen University Hospital, Gentofte, Ledreborg Allé 34, Gentofte, Denmark.

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May 2011

Predictors of indoor fine particulate matter in infants' bedrooms in Denmark.

Environ Res 2011 Jan 6;111(1):87-93. Epub 2010 Nov 6.

Institute of Cancer Epidemiology, Danish Cancer Society, Strandboulevarden 49, 2100 Copenhagen, Denmark.

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http://dx.doi.org/10.1016/j.envres.2010.10.007DOI Listing
January 2011

Elevated exhaled nitric oxide in high-risk neonates precedes transient early but not persistent wheeze.

Am J Respir Crit Care Med 2010 Jul 18;182(2):138-42. Epub 2010 Mar 18.

Copenhagen Prospective Studies on Asthma in Childhood, Danish Pediatric Asthma Center, Health Sciences, University of Copenhagen, Copenhagen University Hospital, Gentofte, Ledreborg Allé 34, 2820 Gentofte, Denmark.

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http://dx.doi.org/10.1164/rccm.200909-1377OCDOI Listing
July 2010