Blake Gilks

Blake Gilks

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Blake Gilks

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Performance Characteristics of Endometrial Sampling in Diagnosis of Endometrial Carcinoma.

Int J Gynecol Pathol 2020 Jan;39(1):19-25

Department of Pathology and Laboratory Medicine, Vancouver General Hospital and University of British Columbia, Vancouver, British Columbia (C.T., H.B., P.B.C., C.B.G.) Department of Laboratory Medicine and Pathobiology, University of Toronto (A.P.) Department of Laboratory Medicine Trillium Health Partners (A.P.) Department of Pathology, Health Sciences Center and University of Manitoba, Winnipeg, Manitoba (N.A.), Canada.

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http://dx.doi.org/10.1097/PGP.0000000000000569DOI Listing
January 2020

Interpretation of somatic POLE mutations in endometrial carcinoma.

J Pathol 2019 Dec 12. Epub 2019 Dec 12.

Department of Pathology and Laboratory Medicine, University of British Columbia and Vancouver General Hospital, Vancouver, Canada.

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http://dx.doi.org/10.1002/path.5372DOI Listing
December 2019

Tubo-Ovarian Transitional Cell Carcinoma and High-grade Serous Carcinoma Show Subtly Different Immunohistochemistry Profiles.

Int J Gynecol Pathol 2019 Nov;38(6):552-561

British Columbia Cancer Agency (J.M., A.N.K., A.T., D.C., D.G.H.) Department of Pathology, University of British Columbia (A.N.K., B.T.-C., C.C., A.C., C.B.G., D.G.H.), Vancouver, British Columbia, Canada Memorial Sloan Kettering Cancer Center, New York, New York (R.S.) Department of Pathology, Maastricht University Medical Center, Maastricht, The Netherlands (S.H.) Department of Women's Health, Tübingen University Hospital, Tübingen (S.K.) Department of Gynecologic Oncology, Kliniken Essen Mitte, Essen (A.D.B.) Gynecologic Oncology Center, Kiel (J.P.) Institute of Pathology, Friedrichshafen (F.K.), Germany.

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http://dx.doi.org/10.1097/PGP.0000000000000538DOI Listing
November 2019

c-KIT Analysis and Targeted Molecular Sequencing of Mesonephric Carcinomas of the Female Genital Tract.

Am J Surg Pathol 2019 Nov 8. Epub 2019 Nov 8.

Department of Anatomical Pathology, Vancouver General Hospital.

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http://dx.doi.org/10.1097/PAS.0000000000001403DOI Listing
November 2019

Association of human papilloma virus status and response to radiotherapy in vulvar squamous cell carcinoma.

Int J Gynecol Cancer 2019 Nov 25. Epub 2019 Nov 25.

Obstetrics and Gynecology, University of British Columbia, Vancouver, British Columbia, Canada

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http://dx.doi.org/10.1136/ijgc-2019-000793DOI Listing
November 2019

Expression of L1 retrotransposon open reading frame protein 1 in gynecologic cancers.

Hum Pathol 2019 Oct 18;92:39-47. Epub 2019 Jun 18.

Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC V5Z 1L3, Canada; Department of Molecular Oncology, BC Cancer Agency, Vancouver, BC V5Z 4E6, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.humpath.2019.06.001DOI Listing
October 2019

Two versus four immunostains for Lynch syndrome screening in endometrial carcinoma.

Histopathology 2019 Sep 26;75(3):442-445. Epub 2019 Jul 26.

Department of Cellular Pathology, Barts Health NHS Trust, London, UK.

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http://dx.doi.org/10.1111/his.13898DOI Listing
September 2019

Precision medicine in endometrial cancer.

Gynecol Oncol 2019 09;154(3):451-453

Professor, Department of Pathology and Laboratory Science, University of British Columbia.

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http://dx.doi.org/10.1016/j.ygyno.2019.08.001DOI Listing
September 2019

Diagnostic Variation in p53 Usage for Endometrial Carcinoma Diagnosis: Implications for Molecular Subtyping.

Int J Gynecol Pathol 2019 Sep 27. Epub 2019 Sep 27.

Departments of Pathology and Laboratory Medicine, University of Saskatchewan, Saskatoon, Saskatchewan (N.B., J.D.C., M.K.) Department of Pathology and Laboratory Medicine, University of British Columbia and Vancouver General Hospital, Vancouver, British Columbia (C.B.G.), Canada.

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http://dx.doi.org/10.1097/PGP.0000000000000638DOI Listing
September 2019

Hematoxylin and Eosin Counterstaining Protocol for Immunohistochemistry Interpretation and Diagnosis.

Appl Immunohistochem Mol Morphol 2019 Aug;27(7):558-563

Centre de recherche du Centre Hospitalier de l'Université de Montréal (CRCHUM).

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http://dx.doi.org/10.1097/PAI.0000000000000626DOI Listing
August 2019

Practical Guidance for Measuring and Reporting Surgical Margins in Vulvar Cancer.

Int J Gynecol Pathol 2019 Aug 26. Epub 2019 Aug 26.

Departments of Obstetrics and Gynecology (K.E.K., M.I.E.V.P.) Pathology (V.T.H.B.M.S., T.B.), Leiden University Medical Centre, Leiden, The Netherlands Department of Pathology, Ghent University Hospital, Gent (K.K.V.D.V.) Department of Pathology, University Hospitals Leuven, Leuven (A.S.V.R.), Belgium Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada (C.B.G.) Department of Cellular Pathology, Princess Alexandra Hospital, Harlow, Essex (S.A.) Department of Cellular Pathology, St. James's University Hospital, Leeds (D.A.) Department of Cellular Pathology, Barts Health NHS Trust, London (A.F., N.S.) Department of Cellular Pathology, University Hospitals Birmingham NHS Trust, Birmingham (R.G., B.T., J.V.) Department of Pathology, Airedale General Hospital, Keighley (N.R.G.) Department of Cellular Pathology, Stepping Hill Hospital, Stockport (R.H.) Department of Histopathology, Manor Hospital, Walsall Healthcare NHS Trust, Walsall (Y.L.H.) Department of Pathology, Belfast Health and Social Care Trust, Belfast (W.G.M.) Department of Cellular Pathology, Royal United Hospital, Bath (P.M.) Department of Pathology, Cambridge University Hospitals NHS Trust, Cambridge (B.R.) Department of Pathology, Royal Derby Hospital, Derby (G.V.S) Department of Histopathology, The Royal Sussex County Hospital, Brighton (M.V.), UK Division of Gynecologic, Breast & Perinatal Pathology, University Hospital Leipzig, Leipzig, Germany (L.C.H.) Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York (K.J.P.).

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http://dx.doi.org/10.1097/PGP.0000000000000631DOI Listing
August 2019

Ovarian Carcinoma Histotype: Strengths and Limitations of Integrating Morphology With Immunohistochemical Predictions.

Int J Gynecol Pathol 2019 Jul;38(4):353-362

Departments of Pathology and Laboratory Medicine (M.K., S.L.) Community Health Sciences (L.S.C.), University of Calgary Department of Cancer Epidemiology and Prevention Research, Alberta Health Services-Cancer Control Alberta (X.G., L.S.C.), Calgary, Alberta Canada's Michael Smith Genome Sciences Centre, BC Cancer Agency, Vancouver; and Department of Biomedical Physiology and Kinesiology, Simon Fraser University, Burnaby (A.B.-W.) Department of Pathology and Laboratory Medicine, University of British Columbia (C.B.G.) Cancer Control Research, BC Cancer Research Centre (N.D.L.), Vancouver, British Columbia, Canada Department of Internal Medicine, Division of Epidemiology, Biostatistics and Preventive Medicine, UNM Comprehensive Cancer Center, University of New Mexico, Albuquerque, New Mexico (L.L., L.S.C.).

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http://Insights.ovid.com/crossref?an=00004347-900000000-9918
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http://dx.doi.org/10.1097/PGP.0000000000000530DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291360PMC
July 2019

Molecular classification defines outcomes and opportunities in young women with endometrial carcinoma.

Gynecol Oncol 2019 06 25;153(3):487-495. Epub 2019 Mar 25.

Department of Gynecology and Obstetrics, Division of Gynecologic Oncology, University of British Columbia, Vancouver, British Columbia, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ygyno.2019.03.098DOI Listing
June 2019

Use of Immunohistochemical Markers (HNF-1β, Napsin A, ER, CTH, and ASS1) to Distinguish Endometrial Clear Cell Carcinoma From Its Morphologic Mimics Including Arias-Stella Reaction.

Int J Gynecol Pathol 2019 May 13. Epub 2019 May 13.

Department of Pathology and Laboratory Medicine, University of British Columbia (J.X.J., B.T.-C, B.G., D.G.H., L.N.H.) Department of Molecular Oncology, British Columbia Cancer Research Centre (D.R.C.) Genetic Pathology Evaluation Centre (S.L., A.S.C., C.C.) Department of Pathology, Vancouver General Hospital (B.G., L.N.H.), Vancouver, British Columbia, Canada.

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http://Insights.ovid.com/crossref?an=00004347-900000000-9910
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http://dx.doi.org/10.1097/PGP.0000000000000609DOI Listing
May 2019

Molecular Subtype Not Immune Response Drives Outcomes in Endometrial Carcinoma.

Clin Cancer Res 2019 Apr 6;25(8):2537-2548. Epub 2018 Dec 6.

Departments of Gynecology and Obstetrics, and University of British Columbia, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1158/1078-0432.CCR-18-3241DOI Listing
April 2019

Diagnostic Accuracy in Fit-for-Purpose PD-L1 Testing.

Appl Immunohistochem Mol Morphol 2019 04;27(4):251-257

Canadian Immunohistochemistry Quality Control.

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http://Insights.ovid.com/crossref?an=00129039-900000000-9873
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http://dx.doi.org/10.1097/PAI.0000000000000734DOI Listing
April 2019

Canadian Consensus-based and Evidence-based Guidelines for Benign Endometrial Pathology Reporting in Biopsy Material.

Int J Gynecol Pathol 2019 Mar;38(2):119-127

Department of Laboratory Medicine and Pathobiology, University of Toronto and Sunnybrook Health Sciences Centre (C.P.-H., M.C., B.D.) Department of Laboratory Medicine and Pathobiology, University of Toronto and Trillium Health Partners (A.P.), Toronto, ON Department of Pathology, University Hospital of Quebec (Centre Hospitalier Universitaire de Quebec), Quebec, QC (K.G.) Department of Pathology and Laboratory Medicine, University of Saskatchewan and Saskatoon City Hospital, Saskatoon, SK (M.K.) Department of Pathology and Laboratory Medicine, University of Calgary and Arnie Charbonneau Cancer Institute, Calgary, AB (M.K.) Department of Laboratory Medicine, Memorial University, St John's, NL (A.P.) Department of Pathology, University of British Columbia and Vancouver General Hospital, Vancouver, BC, Canada (C.B.G.).

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http://dx.doi.org/10.1097/PGP.0000000000000481DOI Listing
March 2019

Bartholin Gland Carcinoma: Clinicopathologic Features, Including p16 Expression and Clinical Outcome.

Int J Gynecol Pathol 2019 Mar;38(2):189-195

Department of Pathology and Laboratory Medicine (T.N., A.S.C., A.N.K., C.B.G.) Genetic Pathology Evaluation Centre (A.S.C.), University of British Columbia Division of Anatomical Pathology, Vancouver General Hospital (T.N., A.N.K., C.B.G.) Division of Medical Oncology, British Columbia Cancer Agency (A.T.), Vancouver, British Columbia, Canada.

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http://Insights.ovid.com/crossref?an=00004347-900000000-9922
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http://dx.doi.org/10.1097/PGP.0000000000000489DOI Listing
March 2019

Synchronous carcinomas of endometrium and ovary: A pragmatic approach.

Gynecol Oncol Rep 2019 Feb 28;27:72-73. Epub 2018 Dec 28.

Dept of Cellular Pathology, BartsHealth NHS Trust, London, UK.

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https://linkinghub.elsevier.com/retrieve/pii/S23525789183012
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http://dx.doi.org/10.1016/j.gore.2018.12.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354202PMC
February 2019

Interpretation of P53 Immunohistochemistry in Endometrial Carcinomas: Toward Increased Reproducibility.

Int J Gynecol Pathol 2019 Jan;38 Suppl 1:S123-S131

Department of Pathology and Laboratory Medicine, University of Calgary, Calgary, Alberta (M.K.) Department of Pathology, Vancouver General Hospital, Vancouver, British Columbia (C.B.G.), Canada Department of Pathology and Gynecology and Obstetrics, The Johns Hopkins Medical Institutions, Baltimore, Maryland (B.M.R.) Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York (R.A.S.) Department of Cellular Pathology, Barts Health NHS Trust, London (N.S.) Department of Pathology, Belfast Health and Social Care Trust, Belfast (W.G.M.), UK.

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http://Insights.ovid.com/crossref?an=00004347-900000000-9921
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http://dx.doi.org/10.1097/PGP.0000000000000488DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127005PMC
January 2019

Issues in the Differential Diagnosis of Uterine Low-grade Endometrioid Carcinoma, Including Mixed Endometrial Carcinomas: Recommendations from the International Society of Gynecological Pathologists.

Int J Gynecol Pathol 2019 Jan;38 Suppl 1:S25-S39

Pathology Department, University of California San Francisco, San Francisco, California (J.T.R.) Department of Pathology and Laboratory Medicine, Vancouver General Hospital and University of British Columbia, Vancouver, British Columbia, Canada (C.B.G.) Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas (A.M.) Department of Pathology, University Hospital Arnau de Vilanova and Department of Pathology, University Hospital de Bellvitge, University of Lleida, IRBLLEIDA, IDIBELL, CIBERONC, Spain (X.M.G.) Department of Pathology, New York University Langone Medical Center, New York, New York (K.M.) Department of Pathology, Brigham and Women's Hospital (G.L.M.) Pathology Department, Massachusetts General Hospital (E.O.), Boston, Massachusetts Pathology Department, Yale New Haven Hospital, New Haven, Connecticut (V.P.) Department of Pathology, Johns Hopkins Medical Institutions (B.M.R.) Department of Pathology, University of Maryland School of Medicine (P.S.), Baltimore, Maryland Department of Histopathology, King Edward Memorial Hospital and School for Women's and Infants' Health, University of Western Australia, Perth, Australia (C.J.R.S.) Department of Pathology, Royal Group of Hospitals Trust, Belfast, Northern Ireland, UK (W.G.M.).

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http://dx.doi.org/10.1097/PGP.0000000000000512DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6296831PMC
January 2019

High-grade Endometrial Carcinomas: Morphologic and Immunohistochemical Features, Diagnostic Challenges and Recommendations.

Int J Gynecol Pathol 2019 Jan;38 Suppl 1:S40-S63

Department of Pathology, Memorial Sloan Kettering Cancer Center (R.M., R.A.S.) New York University Medical Center and School of Medicine, Tisch Hospital (K.M.), New York Department of Pathology, University Hospital, Stony Brook School of Medicine, Stony Brook (C.T.), New York Department of Pathology, Oslo University Hospital, Norwegian Radium Hospital; Faculty of Medicine, Institute of Clinical Medicine, University of Oslo, Oslo, Norway (B.D.) Department of Pathology, University of California San Diego, San Diego (O.F.) Department of Pathology, Cedars-Sinai Medical Center, Los Angeles (J.K.L.R.), California Department of Pathology, Karolinska Institutet, Stockholm, Sweden (J.A.C.) Department of Pathology, Brigham and Women's Hospital, Harvard Medical School (C.P.C.) Department of Pathology, Massachussetts General Hospital, Harvard Medical School (E.O.), Boston, Massachussetts Department of Pathology, University of British Columbia, Vancouver (C.B.G., J.A.I.) Department of Laboratory Medicine, Pathology and Medical Genetics, Royal Jubilee Hospital, Victoria (J.A.I.), BC, Canada Department of Pathology, The University of Texas M. D. Anderson Cancer Center, Houston, Texas (A.M.) Department of Pathology, Hospital University Arnau de Vilanova; and Department of Pathology, Hospital University de Bellvitge, IRBLLEIDA, IDIBELL, University of Lleida, CIBERONC, Barcelona, Spain (X.M.-G.) Department of Pathology, Belfast Health and Social Care Trust, Belfast, UK (W.G.M.) Department of Pathology and Obstetrics and Gynecology, Yale School of Medicine and Yale School of Publich Health, New Haven, Connecticut (V.P.) Department of Pathology, University of Maryland School of Medicine, Baltimore, Maryland (P.N.S.) Department of Pathology, KEMH and School for Women's and Infants' Health, University of Western Australia, Perth, WA, Australia (C.J.R.S.).

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http://dx.doi.org/10.1097/PGP.0000000000000491DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6296248PMC
January 2019

Endometrial Carcinoma Diagnosis: Use of FIGO Grading and Genomic Subcategories in Clinical Practice: Recommendations of the International Society of Gynecological Pathologists.

Int J Gynecol Pathol 2019 Jan;38 Suppl 1:S64-S74

Department of Pathology, Memorial Sloan Kettering Cancer Center, New York (R.A.S, K.J.P.) Department of Pathology, Stony Brook Hospital, SUNY, Stony Brook (C.T.), New York Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, Texas (A.M.) Pathology Department, University Hospital Arnau de Vilanova and University Hospital of Bellvitge, Biomedical Research Institute, and Bellvitge Biomedical Institute, University of Lleida, CIBERONC, Spain (X.M.-G.) Department of Pathology, Massachusetts General Hospital, Boston, Massachusetts (E.O.) Department of Pathology, Yale School of Medicine and the Yale School of Public Health, New Haven, Connecticut (V.P.) Department of Oncology-Pathology, Karolinska Institutet and Department of Pathology and Cytology, Karolinska University Hospital, Stockholm, Sweden (J.C.) Department of Pathology, Belfast Health and Social Care Trust, Belfast, UK (W.G.M.) Department of Pathology and Laboratory Medicine, Vancouver General Hospital and University of British Columbia, Vancouver, BC, Canada (C.B.G.).

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http://dx.doi.org/10.1097/PGP.0000000000000518DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6295928PMC
January 2019

A Comparison of GATA3, TTF1, CD10, and Calretinin in Identifying Mesonephric and Mesonephric-like Carcinomas of the Gynecologic Tract.

Am J Surg Pathol 2018 12;42(12):1596-1606

Department of Pathology and Laboratory Medicine, Vancouver General Hospital and University of British Columbia.

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http://dx.doi.org/10.1097/PAS.0000000000001142DOI Listing
December 2018

Performance Characteristics of Endometrial Sampling in Diagnosis of Endometrial Carcinoma.

Int J Gynecol Pathol 2018 Dec 3. Epub 2018 Dec 3.

Department of Pathology and Laboratory Medicine, Vancouver General Hospital and University of British Columbia, Vancouver, British Columbia (C.T., H.B., P.B.C., C.B.G.) Department of Laboratory Medicine and Pathobiology, University of Toronto (A.P.) Department of Laboratory Medicine Trillium Health Partners (A.P.) Department of Pathology, Health Sciences Center and University of Manitoba, Winnipeg, Manitoba (N.A.), Canada.

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http://dx.doi.org/10.1097/PGP.0000000000000569DOI Listing
December 2018

Artefactual punctate MLH1 staining can lead to erroneous reporting of isolated PMS2 loss.

Histopathology 2018 10 12;73(4):703-705. Epub 2018 Jul 12.

Department of Cellular Pathology Barts Health NHS Trust, London, UK.

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http://dx.doi.org/10.1111/his.13663DOI Listing
October 2018

Endometrial Cancer Presentation and Outcomes Based on Mismatch Repair Protein Expression From a Population-Based Study.

Int J Gynecol Cancer 2018 10;28(8):1624-1630

Department of Laboratory Medicine and Pathology, Lions Gate Hospital, North Vancouver.

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http://dx.doi.org/10.1097/IGC.0000000000001343DOI Listing
October 2018

Histotype classification of ovarian carcinoma: A comparison of approaches.

Gynecol Oncol 2018 10 16;151(1):53-60. Epub 2018 Aug 16.

Huntsman Cancer Institute and Department of Population Health Sciences, University of Utah, 2000 Circle of Hope, Salt Lake City, UT 84112, USA.

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http://dx.doi.org/10.1016/j.ygyno.2018.08.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6292681PMC
October 2018

Does MMR status in endometrial cancer influence response to adjuvant therapy?

Gynecol Oncol 2018 10 29;151(1):76-81. Epub 2018 Aug 29.

BC Cancer Agency, Vancouver, BC, Canada; Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Vancouver, BC, Canada. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00908258183115
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http://dx.doi.org/10.1016/j.ygyno.2018.08.020DOI Listing
October 2018

DICER1 hot-spot mutations in ovarian gynandroblastoma.

Histopathology 2018 Aug 5;73(2):306-313. Epub 2018 Jun 5.

Institute of Pathology, Medizin Campus Bodensee, Friedrichshafen, Germany.

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http://dx.doi.org/10.1111/his.13630DOI Listing
August 2018

Disease Distribution in Low-stage Tubo-ovarian High-grade Serous Carcinoma (HGSC): Implications for Assigning Primary Site and FIGO Stage.

Int J Gynecol Pathol 2018 Jul;37(4):324-330

Departments of Cellular Pathology (N.S., J.L.B., A.Z.F., G.T., S.L.S.L.) Gynaecological Oncology (C.G.), Barts Health NHS Trust Department of Pathology, University College Hospital NHS Trust (R.A.), London Department of Cellular Pathology, Birmingham Women's NHS Foundation Trust, Birmingham (L.H.) Department of Pathology, Belfast Health and Social Care Trust, Belfast, Northern Ireland (K.S., W.G.M.) St James's Hospital, Leeds (N.W.), UK British Columbia Cancer Agency (M.A., F.K.) Department of Pathology and Laboratory Medicine, University of British Columbia (C.B.G.), Vancouver, BC, Canada.

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http://dx.doi.org/10.1097/PGP.0000000000000429DOI Listing
July 2018

Case report: an identical twin with Sertoli-Leydig cell tumor.

Gynecol Endocrinol 2018 Jul 24;34(7):563-566. Epub 2018 Jan 24.

a Department of Obstetrics and Gynaecology, Division of Reproductive Endocrinology and Infertility , University of British Columbia , Vancouver , Canada.

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http://dx.doi.org/10.1080/09513590.2018.1431215DOI Listing
July 2018

The evolution of endometrial carcinoma classification through application of immunohistochemistry and molecular diagnostics: past, present and future.

Virchows Arch 2018 Jun 12;472(6):885-896. Epub 2017 Dec 12.

Department of Anatomic Pathology, Vancouver General Hospital, Vancouver, British Columbia, Canada.

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http://link.springer.com/10.1007/s00428-017-2279-8
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http://dx.doi.org/10.1007/s00428-017-2279-8DOI Listing
June 2018

Hereditary Breast and Ovarian Cancer Syndrome: Moving Beyond BRCA1 and BRCA2.

Adv Anat Pathol 2018 Mar;25(2):85-95

Department of Pathology and Laboratory Medicine, Vancouver General Hospital and University of British Columbia, Vancouver, BC, Canada.

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http://dx.doi.org/10.1097/PAP.0000000000000177DOI Listing
March 2018

MyD88 and TLR4 Expression in Epithelial Ovarian Cancer.

Mayo Clin Proc 2018 03;93(3):307-320

Department of Health Sciences Research, Mayo Clinic, Rochester, MN. Electronic address:

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http://dx.doi.org/10.1016/j.mayocp.2017.10.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870793PMC
March 2018

Synchronous tumours of the female reproductive tract.

Pathology 2018 Feb 14;50(2):214-221. Epub 2017 Dec 14.

Institute of Pathology, Friedrichshafen, Germany.

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http://dx.doi.org/10.1016/j.pathol.2017.10.007DOI Listing
February 2018

Identical TP53 mutations provide evidence that late-recurring tubo-ovarian high-grade serous carcinomas do not represent new peritoneal primaries.

Histopathology 2017 12 22;71(6):1014-1017. Epub 2017 Sep 22.

Department of Pathology, Belfast Health and Social Care Trust, Belfast, UK.

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http://dx.doi.org/10.1111/his.13327DOI Listing
December 2017

Pathology of Ovarian Cancer: Recent Insights Unveiling Opportunities in Prevention.

Clin Obstet Gynecol 2017 12;60(4):686-696

Department of Pathology and Laboratory Medicine, Vancouver General Hospital, University of British Columbia, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1097/GRF.0000000000000314DOI Listing
December 2017

Dose-Response Association of CD8+ Tumor-Infiltrating Lymphocytes and Survival Time in High-Grade Serous Ovarian Cancer.

Authors:
Ellen L Goode Matthew S Block Kimberly R Kalli Robert A Vierkant Wenqian Chen Zachary C Fogarty Aleksandra Gentry-Maharaj Aleksandra Tołoczko Alexander Hein Aliecia L Bouligny Allan Jensen Ana Osorio Andreas Hartkopf Andy Ryan Anita Chudecka-Głaz Anthony M Magliocco Arndt Hartmann Audrey Y Jung Bo Gao Brenda Y Hernandez Brooke L Fridley Bryan M McCauley Catherine J Kennedy Chen Wang Chloe Karpinskyj Christiani B de Sousa Daniel G Tiezzi David L Wachter Esther Herpel Florin Andrei Taran Francesmary Modugno Gregg Nelson Jan Lubiński Janusz Menkiszak Jennifer Alsop Jenny Lester Jesús García-Donas Jill Nation Jillian Hung José Palacios Joseph H Rothstein Joseph L Kelley Jurandyr M de Andrade Luis Robles-Díaz Maria P Intermaggio Martin Widschwendter Matthias W Beckmann Matthias Ruebner Mercedes Jimenez-Linan Naveena Singh Oleg Oszurek Paul R Harnett Peter F Rambau Peter Sinn Philipp Wagner Prafull Ghatage Raghwa Sharma Robert P Edwards Roberta B Ness Sandra Orsulic Sara Y Brucker Sharon E Johnatty Teri A Longacre Eilber Ursula Valerie McGuire Weiva Sieh Yanina Natanzon Zheng Li Alice S Whittemore deFazio Anna Annette Staebler Beth Y Karlan Blake Gilks David D Bowtell Estrid Høgdall Francisco J Candido dos Reis Helen Steed Ian G Campbell Jacek Gronwald Javier Benítez Jennifer M Koziak Jenny Chang-Claude Kirsten B Moysich Linda E Kelemen Linda S Cook Marc T Goodman María José García Peter A Fasching Stefan Kommoss Suha Deen Susanne K Kjaer Usha Menon James D Brenton Paul DP Pharoah Georgia Chenevix-Trench David G Huntsman Stacey J Winham Martin Köbel Susan J Ramus

JAMA Oncol 2017 12;3(12):e173290

School of Women’s and Children’s Health, University of New South Wales, Sydney, Australia

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http://dx.doi.org/10.1001/jamaoncol.2017.3290DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5744673PMC
December 2017

Frequent Mismatch Repair Protein Deficiency in Mixed Endometrioid and Clear Cell Carcinoma of the Endometrium.

Int J Gynecol Pathol 2017 Nov;36(6):555-561

Department of Pathology and Laboratory Medicine, Calgary Laboratory Services and University of Calgary, Calgary (M.K.) Department of Laboratory Medicine and Pathology, Royal Alexandra Hospital and University of Alberta, Edmonton (C.-H.L.), AB Department of Pathology and Laboratory Medicine, Vancouver General Hospital and University of British Columbia (B.T.-C., J.L., L.N.H., C.B.G.) Department of Pathology, British Columbia Cancer Agency (C.-H.L.), Vancouver, BC, Canada Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY (R.A.S., D.D.) Department of Histopathology, King Edward Memorial Hospital and School for Women's and Infants' Health, University of Western Australia, Perth, WA, Australia (C.J.R.S.).

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November 2017

HPV-independent Differentiated Vulvar Intraepithelial Neoplasia (dVIN) is Associated With an Aggressive Clinical Course.

Int J Gynecol Pathol 2017 Nov;36(6):507-516

Department of Gynecology and Obstetrics, Division of Gynecologic Oncology, University of British Columbia (J.N.M., S.Y.K., D.M.M.) Department of Pathology and Laboratory Medicine, University of British Columbia and BC Cancer Agency (A.A., S.E., C.B.G.) Vancouver, BC, Canada Department of Applied Tumor Biology, Institute of Pathology, University of Heidelberg, and Clinical Cooperation Unit Applied Tumor Biology, German Cancer Research Center (DKFZ), Heidelberg, Germany (M.R., M.v.K.D., E.S.P.) Department of Cellular Pathology, Barts and the London NHS Trust, London, UK (S.J., N.S.).

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http://dx.doi.org/10.1097/PGP.0000000000000375DOI Listing
November 2017

Survival Benefit of Adjuvant Radiotherapy: An Analysis of Low-Stage Invasive Ovarian Mucinous Carcinomas.

Int J Gynecol Cancer 2017 11;27(9):1819-1825

*BC Cancer Agency, Surrey Clinic, Surrey; and †Cancer Control, British Columbia Cancer Research Centre; ‡Cheryl Brown Ovarian Cancer Outcomes Unit, OvCaRe; §Vancouver General Hospital and University of British Columbia; and ∥BC Cancer Agency, Vancouver Clinic, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1097/IGC.0000000000001124DOI Listing
November 2017

Molecular subtyping of mammary-like adenocarcinoma of the vulva shows molecular similarity to breast carcinomas.

Histopathology 2017 Sep 16;71(3):446-452. Epub 2017 Jun 16.

Division of Anatomical Pathology, Vancouver General Hospital, University of British Columbia, Vancouver, Canada.

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http://dx.doi.org/10.1111/his.13239DOI Listing
September 2017

High-grade serous carcinoma of tubo-ovarian origin: recent developments.

Histopathology 2017 Sep 18;71(3):339-356. Epub 2017 Jul 18.

Department of Anatomic Pathology, Vancouver General Hospital, Vancouver, Canada.

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http://dx.doi.org/10.1111/his.13248DOI Listing
September 2017

Human papillomavirus (HPV)-independent vulvar squamous cell carcinoma has a worse prognosis than HPV-associated disease: a retrospective cohort study.

Histopathology 2017 Aug 23;71(2):238-246. Epub 2017 May 23.

Department of Pathology and Laboratory Medicine, University of British Columbia and BC Cancer Agency, Vancouver, BC, Canada.

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http://dx.doi.org/10.1111/his.13205DOI Listing
August 2017

Assessment of CK17 as a Marker for the Diagnosis of Differentiated Vulvar Intraepithelial Neoplasia.

Int J Gynecol Pathol 2017 May;36(3):273-280

Department of Pathology and Laboratory Medicine, University of Louisville, Louisville, Kentucky (M.B.P., M.A.S.)Department of Pathology, Floyd Memorial Hospital, New Albany, Indiana (M.M.)Department of Cellular Pathology, Barts and the London NHS Trust, London, United Kingdom (N.S.)Department of Pathology and Laboratory Medicine, Vancouver General Hospital and University of British Columbia, Vancouver, Canada (C.B.G.).

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http://dx.doi.org/10.1097/PGP.0000000000000317DOI Listing
May 2017

Frequent NFIB-associated Gene Rearrangement in Adenoid Cystic Carcinoma of the Vulva.

Int J Gynecol Pathol 2017 May;36(3):289-293

Department of Pathology (D.X., B.M.R.), The Johns Hopkins Medical Institutions, Baltimore, MDDepartment of Pathology and Laboratory Medicine (S.B., N.M., J.H., D.G.H., C.B.G., H.H.), University of British Columbia, Vancouver, BC, CanadaCellNetix Pathology (C.I.), Seattle, WA.

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http://dx.doi.org/10.1097/PGP.0000000000000324DOI Listing
May 2017

The Fallopian Tube Origin and Primary Site Assignment in Extrauterine High-grade Serous Carcinoma: Findings of a Survey of Pathologists and Clinicians.

Int J Gynecol Pathol 2017 May;36(3):230-239

Department of Pathology (W.G.M.), Belfast Health and Social Care Trust, BelfastDepartment of Cellular Pathology (L.H.), Birmingham Women's NHS Trust, BirminghamDepartment of Pathology (N.W.), St James's Hospital, LeedsDepartment of Cellular Pathology (N.S.), Barts Health NHS Trust, London, UKDepartment of Anatomic Pathology (C.B.G.), Vancouver General Hospital, Vancouver, BC, Canada.

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http://dx.doi.org/10.1097/PGP.0000000000000336DOI Listing
May 2017

Ovarian carcinoma histotype in Lynch syndrome.

Gynecol Oncol Rep 2017 May 16;20:140-141. Epub 2017 Mar 16.

Dept of Human Genetics, McGill University, Montreal, QC, Canada.

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http://dx.doi.org/10.1016/j.gore.2017.03.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993521PMC
May 2017

Cancer-Associated Mutations in Endometriosis without Cancer.

N Engl J Med 2017 05;376(19):1835-1848

From the Departments of Obstetrics and Gynaecology (M.S.A., C.A., C.W., P.J.Y., D.G.H.) and Pathology and Laboratory Medicine (M.S.A., T.M.N., J. Senz, B.T.-C., C.B.G., D.G.H.), University of British Columbia, the Department of Anatomical Pathology, Vancouver General Hospital (T.M.N., H.M.H., J.H., V.L., B.T.-C., A.W., C.B.G., D.G.H.), the Department of Molecular Oncology, British Columbia Cancer Agency (H.M.H., A.L., V.L., N.B., D.G.H.), and the BC Women's Centre for Pelvic Pain and Endometriosis, BC Women's Hospital and Health Centre (F.W., N.O., C.A., C.W., P.J.Y.) - all in Vancouver, BC, Canada; the Department of Oncology (N.P., C.T., K.W.K., L.D., T.-L.W., B.V., I.-M.S.) and Ludwig Center (N.P., Y.W., J.D.C., M.Z., M.P., W.M., A.M., K.W.K., L.D., B.V.), Sidney Kimmel Comprehensive Cancer Center, the Departments of Pathology (N.P., A.A., M.N., L.D.W., T.-L.W., B.V., I.-M.S.) and Gynecology and Obstetrics (J. Segars, I.-M.S.), Johns Hopkins Medical Institutions, Personal Genome Diagnostics (S.J.), and Johns Hopkins University Howard Hughes Medical Institute (B.V.) - all in Baltimore; the Department of Pathology, Seirei Mikatahara Hospital (A.A., H.O.), and the Department of Tumor Pathology, Hamamatsu University School of Medicine (A.A.), Hamamatsu, and the Department of Molecular Pathology, Hiroshima University School of Medicine, Hiroshima (A.A.) - all in Japan; the Department of Pathology, University Medical Center Utrecht, Utrecht, the Netherlands (M.N.); the Departments of Obstetrics and Gynecology (T.S.) and Pathology (R.A., A.H.), Lenox Hill Hospital-Northwell Health (Hofstra University), New York; and the Department of Pathology, Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Tao-Yuan City, Taiwan (R.-C.W.).

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http://dx.doi.org/10.1056/NEJMoa1614814DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5555376PMC
May 2017

Evolution of Quality Assurance for Clinical Immunohistochemistry in the Era of Precision Medicine: Part 4: Tissue Tools for Quality Assurance in Immunohistochemistry.

Appl Immunohistochem Mol Morphol 2017 04;25(4):227-230

*Department of Laboratory Medicine and Pathobiology, University of Toronto Departments of †Pathology §§§§Laboratory Hematology, University Health Network, Toronto, ON §§Vancouver General Hospital, University of British Columbia, Vancouver, BC ###Department of Pathology and Laboratory Medicine, Cumming School of Medicine, University of Calgary, Calgary, AB ∥∥∥∥Canadian Immunohistochemistry Quality Control (CIQC)/Canadian Association of Pathologists National Standards Committee for High Complexity Testing/Immunohistochemistry, Canada ‡Poundbury Cancer Institute §Dorset County Hospital NHS Foundation Trust ∥Cancer Diagnostic Quality Assurance Services (CADQAScic), Dorchester ¶¶Department of Surgery & Cancer, Division of Cancer, Imperial College London ***UK National External Quality Assessment Scheme (UK NEQAS), University College London, London, UK ∥∥International Quality Network for Pathology (IQN Path), Luxembourg City, Luxembourg ¶School of Medicine, Institute of Pathology, Charité-University Hospital Berlin, Berlin, Germany #Griffith University, Gold Coast ††Genomics For Life, Brisbane, Qld **RCPA Quality Assurance Program, Sydney, NSW, Australia ‡‡Phenopath, Seattle, WA ##Brigham and Women's Hospital, Harvard Medical School, Boston, MA ****Keck School of Medicine, University of Southern California, Los Angeles, CA †††Center of Predictive Molecular Medicine ‡‡‡Center for Excellence on Ageing and Translational Medicine, University of Chieti-Pescara, Chieti, Italy §§§Department of Pathology, Radboud University Medical Centre, Nijmegen, The Netherlands ∥∥∥Institute of Pathology, Aalborg University Hospital and Department of Clinical Medicine, Aalborg University ¶¶¶Nordic Immunohistochemistry Quality Control (NordiQC), Aalborg, Denmark ††††Department of Pathology, Beijing Friendship Hospital, Capital Medical University, Beijing ‡‡‡‡Chinese Committee for Pathologists-Immunohistochemistry Quality Control, China.

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http://dx.doi.org/10.1097/PAI.0000000000000469DOI Listing
April 2017

The Chemotherapy Response Score (CRS): Interobserver Reproducibility in a Simple and Prognostically Relevant System for Reporting the Histologic Response to Neoadjuvant Chemotherapy in Tuboovarian High-grade Serous Carcinoma.

Int J Gynecol Pathol 2017 Mar;36(2):172-179

Department of Cellular Pathology (I.S., A.Z.F., S.J., S.L.S.L., J.M., T.O.M., N.S.) Department of Medical Oncology (S.B.), Barts Health NHS Trust Department of Pathology (P.E., G.T.), University College Hospital NHS Trust, London Department of Cellular Pathology (J.B., R.G., L.H., R.M., J.V.), Birmingham Women's NHS Trust, Birmingham Department of Pathology (W.G.M.), Belfast Health and Social Care Trust, Royal Victoria Hospital, Belfast, UK Department of Anatomic Pathology (C.B.G.), Vancouver General Hospital, Vancouver, BC, Canada.

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http://dx.doi.org/10.1097/PGP.0000000000000307DOI Listing
March 2017

Confirmation of ProMisE: A simple, genomics-based clinical classifier for endometrial cancer.

Cancer 2017 03 6;123(5):802-813. Epub 2017 Jan 6.

Department of Gynecology and Obstetrics, Division of Gynecologic Oncology, University of British Columbia, Vancouver, British Columbia, Canada.

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http://dx.doi.org/10.1002/cncr.30496DOI Listing
March 2017

Evolution of Quality Assurance for Clinical Immunohistochemistry in the Era of Precision Medicine. Part 3: Technical Validation of Immunohistochemistry (IHC) Assays in Clinical IHC Laboratories.

Appl Immunohistochem Mol Morphol 2017 03;25(3):151-159

*Department of Laboratory Medicine and Pathobiology, University of Toronto Departments of †Laboratory Hematology §Pathology, University Health Network, Toronto, ON ∥∥Vancouver General Hospital, University of British Columbia, Vancouver, BC ¶¶¶Department of Pathology and Laboratory Medicine, Cumming School of Medicine University of Calgary, and Calgary Laboratory Services, Calgary, AB, Canada ‡Canadian Immunohistochemistry Quality Control (CIQC), Vancouver, BC, Canada/Canadian Association of Pathologists National Standards Committee for High Complexity Testing/Immunohistochemistry ∥Poundbury Cancer Institute ¶Dorset County Hospital NHS Foundation Trust, Dorchester, UK #Cancer Diagnostic Quality Assurance Services (CADQAScic), Dorchester ***UK National External Quality Assessment Scheme (UK NEQAS), University College London, London, UK **School of Medicine, Institute of Pathology, Charité-University Hospital, Berlin, Berlin, Germany ††Griffith University, Gold Coast ‡‡RCPA Quality Assurance Program, Sydney §§Genomics For Life, Brisbane, Australia ¶¶International Quality Network for Pathology (IQN Path), Luxembourg City, Luxembourg ##Brigham and Women's Hospital, Harvard Medical School, Boston, MA †††Center of Predictive Molecular Medicine, Center for Excellence on Ageing and Translational Medicine, University of Chieti-Pescara, Chieti, Italy ‡‡‡Department of Pathology, Radboud University Medical Centre, Nijmegen, The Netherlands §§§Institute of Pathology, and Department of Clinical Medicine, Aalborg University, Aalborg University Hospital ∥∥∥Nordic Immunohistochemistry Quality Control (NordiQC), Aalborg, Denmark ###Department of Pathology, Beijing Friendship Hospital, Capital Medical University, Beijing ****Chinese Committee for Pathologists-Immunohistochemistry Quality Control, China ††††Keck School of Medicine, University of Southern California, Los Angeles, CA.

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http://dx.doi.org/10.1097/PAI.0000000000000470DOI Listing
March 2017

Uterine Serous Carcinomas Frequently Metastasize to the Fallopian Tube and Can Mimic Serous Tubal Intraepithelial Carcinoma.

Am J Surg Pathol 2017 Feb;41(2):161-170

*Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, BC, Canada †Department of Cellular Pathology, Barts NHS Trust ‡Department of Cellular Pathology, Barts and the London NHS Trust, London §St James's Hospital, Leeds ∥Department of Pathology, Belfast Health and Social Care Trust, Belfast, Northern Ireland, United Kingdom.

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http://dx.doi.org/10.1097/PAS.0000000000000757DOI Listing
February 2017

Interobserver Agreement in Endometrial Carcinoma Histotype Diagnosis Varies Depending on The Cancer Genome Atlas (TCGA)-based Molecular Subgroup.

Am J Surg Pathol 2017 Feb;41(2):245-252

*Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, NY †Department of Pathology and Laboratory Medicine, and Genetic Pathology Evaluation Center, Vancouver General Hospital, University of British Columbia **Department of Gynecology and Obstetrics, University of British Columbia, Vancouver, BC ‡Department of Pathology, Saskatoon City Hospital, Saskatoon, SK §Department of Pathology, Laval University, Quebec City #Department of Human Genetics, McGill University, Research Institute of the McGill University Health Network, Montreal, QC ∥Department of Laboratory Medicine and Pathology, Royal Alexandra Hospital, University of Alberta, Edmonton ¶Department of Pathology and Laboratory Medicine, Calgary Laboratory Services, University of Calgary, Calgary, AB, Canada.

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http://dx.doi.org/10.1097/PAS.0000000000000764DOI Listing
February 2017

Evolution of Quality Assurance for Clinical Immunohistochemistry in the Era of Precision Medicine - Part 2: Immunohistochemistry Test Performance Characteristics.

Appl Immunohistochem Mol Morphol 2017 02;25(2):79-85

*Department of Laboratory Medicine and Pathobiology, University of Toronto, Vancouver, BC, CanadaDepartment of †Laboratory Hematology§Pathology, University Health Network, Toronto, ON, Canada‡Canadian Immunohistochemistry Quality Control (CIQC)/Canadian Association of Pathologists National Standards Committee for High Complexit Testing/Immunohistochemistry∥Poundbury Cancer Institute¶Dorset County Hospital NHS Foundation Trust#Cancer Diagnostic Quality Assurance Services (CADQAScic), Dorchester, UK***UK National External Quality Assessment Scheme (UK NEQAS), University College London, London, UK**"Rudolf-Virchow-Haus", Institute of Pathology, Charité-University Hospital Berlin, Berlin, Germany††School of Medicine, Griffith University, Gold Coast‡‡Genomics For Life, Brisbane, QLD§§RCPA Quality Assurance Program, Sydney, NSW, Australia∥∥Vancouver General Hospital, University of British Columbia, Vancouver, BC, Canada¶¶International Quality Network for Pathology (IQN Path), Luxembourg City, Luxembourg, and Division of Cancer, Department of Surgery & Cancer, Imperial College London, UK##Brigham and Women's Hospital, Harvard Medical School, Boston, MA†††Center of Predictive Molecular Medicine, Center for Excellence on Ageing and Translational Medicine, University of Chieti-Pescara, Chieti, Italy‡‡‡Department of Pathology, Radboud University Medical Centre, Nijmegen, The Netherlands§§§Institute of Pathology, Aalborg University Hospital and Department of Clinical Medicine, Aalborg University, Denmark∥∥∥Nordic Immunohistochemistry Quality Control (NordiQC), Aalborg, Denmark¶¶¶Department of Pathology and Laboratory Medicine, Cumming School of Medicine, University of Calgary and Calgary Laboratory Services, Calgary, AB###Department of Pathology, Beijing Friendship Hospital, Capital Medical University****CCP-IHCQC, Chinese Committee for Pathologists-Immunohistochemistry Quality Control, Beijing, China††††Keck School of Medicine, University of Southern California, Los Angeles, CA.

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http://dx.doi.org/10.1097/PAI.0000000000000444DOI Listing
February 2017

Basal biomarkers nestin and INPP4b identify intrinsic subtypes accurately in breast cancers that are weakly positive for oestrogen receptor.

Histopathology 2017 Jan 29;70(2):185-194. Epub 2016 Sep 29.

Department of Pathology and Laboratory Medicine, Genetic Pathology Evaluation Centre, University of British Columbia, Vancouver, BC, Canada.

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http://dx.doi.org/10.1111/his.13038DOI Listing
January 2017

FOXL2 402C>G Mutation Can Be Identified in the Circulating Tumor DNA of Patients with Adult-Type Granulosa Cell Tumor.

J Mol Diagn 2017 01 1;19(1):126-136. Epub 2016 Nov 1.

Department of Pathology and Laboratory Medicine, University of British Columbia, and the Department of Molecular Oncology, BC Cancer Agency, Vancouver, British Columbia, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jmoldx.2016.08.005DOI Listing
January 2017

The disparate origins of ovarian cancers: pathogenesis and prevention strategies.

Nat Rev Cancer 2017 01 25;17(1):65-74. Epub 2016 Nov 25.

Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver, British Columbia V5Z 1M9, Canada.

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http://dx.doi.org/10.1038/nrc.2016.113DOI Listing
January 2017

Evolution of Quality Assurance for Clinical Immunohistochemistry in the Era of Precision Medicine: Part 1: Fit-for-Purpose Approach to Classification of Clinical Immunohistochemistry Biomarkers.

Appl Immunohistochem Mol Morphol 2017 01;25(1):4-11

*Department of Laboratory Medicine and Pathobiology, University of Toronto †Department of Pathology, University Health Network ††††Department of Laboratory Hematology, University Health Network, Toronto, ON ‡‡Vancouver General Hospital, University of British Columbia, Vancouver, BC ∥∥∥Department of Pathology and Laboratory Medicine, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada ‡Poundbury Cancer Institute §Dorset County Hospital NHS Foundation Trust ∥Cancer Diagnostic Quality Assurance Services (CADQAScic), Dorchester ∥∥Division of Cancer, Department of Surgery & Cancer, Imperial College, London, UK ##UK National External Quality Assessment Scheme (UK NEQAS), University College London, London, UK ¶School of Medicine, Institute of Pathology, Charité-University Hospital Berlin, Berlin, Germany #Griffith University, Gold Coast **RCPA Quality Assurance Program, Sydney ††Genomics For Life, Brisbane, Australia §§International Quality Network for Pathology (IQN Path), Luxembourg City, Luxembourg ¶¶Brigham and Women's Hospital, Harvard Medical School, Boston, MA ***Center of Predictive Molecular Medicine, Center for Excellence on Ageing and Translational Medicine, University of Chieti-Pescara, Chieti, Italy †††Department of Pathology, Radboud University Medical Centre, Nijmegen, The Netherlands ‡‡‡Institute of Pathology, Aalborg University Hospital and Department of Clinical Medicine, Aalborg University §§§Nordic Immunohistochemistry Quality Control (NordiQC), Aalborg, Denmark ¶¶¶Keck School of Medicine, University of Southern California, Los Angeles, CA ###Department of Pathology, Beijing Friendship Hospital, Capital Medical University, Beijing, China ****Chinese Committee for Pathologists-Immunohistochemistry Quality Control ‡‡‡‡Canadian Immunohistochemistry Quality Control (CIQC)/Canadian Association of Pathologists National Standards Committee for High Complexity Testing/Immunohistochemistry, Vancouver, BC, Canada.

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http://dx.doi.org/10.1097/PAI.0000000000000451DOI Listing
January 2017

The changing landscape of gynaecological cancer diagnosis: implications for histopathological practice in the 21st century.

Histopathology 2017 Jan;70(1):56-69

Department of Anatomic Pathology, Vancouver General Hospital, Vancouver, BC, Canada.

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http://doi.wiley.com/10.1111/his.13080
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http://dx.doi.org/10.1111/his.13080DOI Listing
January 2017

Concurrent ARID1A and ARID1B inactivation in endometrial and ovarian dedifferentiated carcinomas.

Mod Pathol 2016 12 26;29(12):1586-1593. Epub 2016 Aug 26.

Department of Laboratory Medicine and Pathology, Royal Alexandra Hospital and University of Alberta, Edmonton, Alberta, Canada.

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http://dx.doi.org/10.1038/modpathol.2016.156DOI Listing
December 2016

Tea, coffee, and caffeinated beverage consumption and risk of epithelial ovarian cancers.

Cancer Epidemiol 2016 12 27;45:119-125. Epub 2016 Oct 27.

Cancer Control Research, BC Cancer Research Centre, Vancouver, British Columbia, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.canep.2016.10.010DOI Listing
December 2016

Molecularly Defined Adult Granulosa Cell Tumor of the Ovary: The Clinical Phenotype.

J Natl Cancer Inst 2016 11 13;108(11). Epub 2016 Jun 13.

Department of Pathology and Laboratory Medicine, University of British Columbia, Vancouver General Hospital and BC Cancer Agency, Vancouver, Canada (MKM, HMH, AT, WY, NR, CBG, DGH); Biomedicum Helsinki, University of Helsinki, Helsinki, Finland (AF, LUK, SB, MA); Department of Obstetrics and Gynecology, Helsinki University Hospital, Helsinki, Finland (AF, LUK, SB, MA); Centre of Gynaecologic Oncology Amsterdam (HSvM, MRB, GGK) and Department of Pathology (JBGH, GKJH, MJvdV, MCGB), Academic Medical Center, Amsterdam, the Netherlands; Children's Hospital, University of Helsinki and Helsinki University Hospital, Helsinki, Finland (NA, MH); Department of Obstetrics and Gynaecology, Tübingen University Hospital, Department of Women's Health, Tübingen, Germany (KZ, SYB, BK, SK); Department of Pathology (RB) and Department of Clinical Chemistry and Hematology (MA), Helsinki University Hospital, University of Helsinki and HUSLAB, Helsinki, Finland; Institute of Pathology, Tübingen University Hospital, Tübingen, Germany (AS); Department of Pediatrics, Washington University School of Medicine, St. Louis Children's Hospital, St. Louis, MO (MH); Department of Obstetrics and Gynaecology, University of British Columbia, Vancouver, BC, Canada (DGH); Department of Human Genetics, Research Institute of the McGill University Health Centre, McGill University, Montreal, QC, Canada (MKM)

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http://dx.doi.org/10.1093/jnci/djw134DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241905PMC
November 2016

Immunophenotypic features of dedifferentiated endometrial carcinoma - insights from BRG1/INI1-deficient tumours.

Histopathology 2016 Oct 5;69(4):560-9. Epub 2016 Jul 5.

Department of Laboratory Medicine and Pathology, Royal Alexandra Hospital and University of Alberta, Edmonton, AB, Canada.

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http://dx.doi.org/10.1111/his.12989DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5516928PMC
October 2016

Molecular classification of endometrial carcinoma on diagnostic specimens is highly concordant with final hysterectomy: Earlier prognostic information to guide treatment.

Gynecol Oncol 2016 10 14;143(1):46-53. Epub 2016 Jul 14.

Department of Gynecology and Obstetrics, Division of Gynecologic Oncology, University of British Columbia, 2775 Laurel St., 6th Floor, Vancouver, British Columbia V5Z 1M9, Canada. Electronic address:

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5521211PMC
October 2016

Association of vitamin D levels and risk of ovarian cancer: a Mendelian randomization study.

Authors:
Jue-Sheng Ong Gabriel Cuellar-Partida Yi Lu Peter A Fasching Alexander Hein Stefanie Burghaus Matthias W Beckmann Diether Lambrechts Els Van Nieuwenhuysen Ignace Vergote Adriaan Vanderstichele Jennifer Anne Doherty Mary Anne Rossing Jenny Chang-Claude Ursula Eilber Anja Rudolph Shan Wang-Gohrke Marc T Goodman Natalia Bogdanova Thilo Dörk Matthias Dürst Peter Hillemanns Ingo B Runnebaum Natalia Antonenkova Ralf Butzow Arto Leminen Heli Nevanlinna Liisa M Pelttari Robert P Edwards Joseph L Kelley Francesmary Modugno Kirsten B Moysich Roberta B Ness Rikki Cannioto Estrid Høgdall Claus K Høgdall Allan Jensen Graham G Giles Fiona Bruinsma Susanne K Kjaer Michelle At Hildebrandt Dong Liang Karen H Lu Xifeng Wu Maria Bisogna Fanny Dao Douglas A Levine Daniel W Cramer Kathryn L Terry Shelley S Tworoger Meir Stampfer Stacey Missmer Line Bjorge Helga B Salvesen Reidun K Kopperud Katharina Bischof Katja Kh Aben Lambertus A Kiemeney Leon Fag Massuger Angela Brooks-Wilson Sara H Olson Valerie McGuire Joseph H Rothstein Weiva Sieh Alice S Whittemore Linda S Cook Nhu D Le C Blake Gilks Jacek Gronwald Anna Jakubowska Jan Lubiński Tomasz Kluz Honglin Song Jonathan P Tyrer Nicolas Wentzensen Louise Brinton Britton Trabert Jolanta Lissowska John R McLaughlin Steven A Narod Catherine Phelan Hoda Anton-Culver Argyrios Ziogas Diana Eccles Ian Campbell Simon A Gayther Aleksandra Gentry-Maharaj Usha Menon Susan J Ramus Anna H Wu Agnieszka Dansonka-Mieszkowska Jolanta Kupryjanczyk Agnieszka Timorek Lukasz Szafron Julie M Cunningham Brooke L Fridley Stacey J Winham Elisa V Bandera Elizabeth M Poole Terry K Morgan Harvey A Risch Ellen L Goode Joellen M Schildkraut Celeste L Pearce Andrew Berchuck Paul Dp Pharoah Georgia Chenevix-Trench Puya Gharahkhani Rachel E Neale Penelope M Webb Stuart MacGregor

Int J Epidemiol 2016 10 4;45(5):1619-1630. Epub 2016 Sep 4.

Statistical Genetics laboratory, QIMR Berghofer Medical Research Institute, Herston, QLD 4006, Australia,

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http://dx.doi.org/10.1093/ije/dyw207DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5100621PMC
October 2016

Ovarian carcinoma diagnosis: the clinical impact of 15 years of change.

Br J Cancer 2016 10 15;115(8):993-999. Epub 2016 Sep 15.

Department of Pathology and Laboratory Medicine, University of British Columbia, 910 West 10th Avenue, Vancouver, BC, Canada V5Z 4E3.

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http://dx.doi.org/10.1038/bjc.2016.273DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5061905PMC
October 2016

Classification of Extraovarian Implants in Patients With Ovarian Serous Borderline Tumors (Tumors of Low Malignant Potential) Based on Clinical Outcome.

Am J Surg Pathol 2016 09;40(9):1155-64

*Department of Pathology, Stanford University School of Medicine, Stanford, CA †Vancouver General Hospital and University of British Columbia, Vancouver, BC.

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http://dx.doi.org/10.1097/PAS.0000000000000692DOI Listing
September 2016

Assessing the genetic architecture of epithelial ovarian cancer histological subtypes.

Authors:
Gabriel Cuellar-Partida Yi Lu Suzanne C Dixon Peter A Fasching Alexander Hein Stefanie Burghaus Matthias W Beckmann Diether Lambrechts Els Van Nieuwenhuysen Ignace Vergote Adriaan Vanderstichele Jennifer Anne Doherty Mary Anne Rossing Jenny Chang-Claude Anja Rudolph Shan Wang-Gohrke Marc T Goodman Natalia Bogdanova Thilo Dörk Matthias Dürst Peter Hillemanns Ingo B Runnebaum Natalia Antonenkova Ralf Butzow Arto Leminen Heli Nevanlinna Liisa M Pelttari Robert P Edwards Joseph L Kelley Francesmary Modugno Kirsten B Moysich Roberta B Ness Rikki Cannioto Estrid Høgdall Claus Høgdall Allan Jensen Graham G Giles Fiona Bruinsma Susanne K Kjaer Michelle A T Hildebrandt Dong Liang Karen H Lu Xifeng Wu Maria Bisogna Fanny Dao Douglas A Levine Daniel W Cramer Kathryn L Terry Shelley S Tworoger Meir Stampfer Stacey Missmer Line Bjorge Helga B Salvesen Reidun K Kopperud Katharina Bischof Katja K H Aben Lambertus A Kiemeney Leon F A G Massuger Angela Brooks-Wilson Sara H Olson Valerie McGuire Joseph H Rothstein Weiva Sieh Alice S Whittemore Linda S Cook Nhu D Le C Blake Gilks Jacek Gronwald Anna Jakubowska Jan Lubiński Tomasz Kluz Honglin Song Jonathan P Tyrer Nicolas Wentzensen Louise Brinton Britton Trabert Jolanta Lissowska John R McLaughlin Steven A Narod Catherine Phelan Hoda Anton-Culver Argyrios Ziogas Diana Eccles Ian Campbell Simon A Gayther Aleksandra Gentry-Maharaj Usha Menon Susan J Ramus Anna H Wu Agnieszka Dansonka-Mieszkowska Jolanta Kupryjanczyk Agnieszka Timorek Lukasz Szafron Julie M Cunningham Brooke L Fridley Stacey J Winham Elisa V Bandera Elizabeth M Poole Terry K Morgan Ellen L Goode Joellen M Schildkraut Celeste L Pearce Andrew Berchuck Paul D P Pharoah Penelope M Webb Georgia Chenevix-Trench Harvey A Risch Stuart MacGregor

Hum Genet 2016 07 13;135(7):741-56. Epub 2016 Apr 13.

Statistical Genetics, QIMR Berghofer Medical Research Institute, 300 Herston Road, Herston, QLD, 4006, Australia.

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http://dx.doi.org/10.1007/s00439-016-1663-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4976079PMC
July 2016

Ovarian Cancer in Hereditary Cancer Susceptibility Syndromes.

Surg Pathol Clin 2016 Jun 11;9(2):189-99. Epub 2016 Apr 11.

Department of Pathology and Laboratory Medicine, Vancouver General Hospital, University of British Columbia, Room 1200, 1st Floor JPPN, 855 West 10th Avenue, Vancouver, British Columbia V5Z 1M9, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.path.2016.01.003DOI Listing
June 2016