Blaine N Armbruster

Blaine N Armbruster

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Blaine N Armbruster

Blaine N Armbruster

Publications by authors named "Blaine N Armbruster"

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A chemical-genetic approach to study G protein regulation of beta cell function in vivo.

Proc Natl Acad Sci U S A 2009 Nov 26;106(45):19197-202. Epub 2009 Oct 26.

Molecular Signaling Section, Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1073/pnas.0906593106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2767362PMC
November 2009

New insights into the function of M4 muscarinic acetylcholine receptors gained using a novel allosteric modulator and a DREADD (designer receptor exclusively activated by a designer drug).

Mol Pharmacol 2008 Oct 15;74(4):1119-31. Epub 2008 Jul 15.

Drug Discovery Biology Laboratory, Monash Institute of Pharmaceutical Sciences, Department of Pharmacology, Monash University, Clayton, Victoria 3800, Australia.

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http://molpharm.aspetjournals.org/cgi/doi/10.1124/mol.108.04
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http://dx.doi.org/10.1124/mol.108.049353DOI Listing
October 2008

Distinct functions of POT1 at telomeres.

Mol Cell Biol 2008 Sep 2;28(17):5251-64. Epub 2008 Jun 2.

Department of Pharmacology and Cancer Biology, Department of Radiation Oncology, Duke University Medical Center, Durham, NC 27710, USA.

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http://mcb.asm.org/content/28/17/5251.full.pdf
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http://mcb.asm.org/cgi/doi/10.1128/MCB.00048-08
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http://dx.doi.org/10.1128/MCB.00048-08DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2519730PMC
September 2008

Biochemical analysis of inositol phosphate kinases.

Methods Enzymol 2007 ;434:171-85

Howard Hughes Medical Institute, Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina, USA.

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http://dx.doi.org/10.1016/S0076-6879(07)34010-XDOI Listing
December 2007

Evolving the lock to fit the key to create a family of G protein-coupled receptors potently activated by an inert ligand.

Proc Natl Acad Sci U S A 2007 Mar 2;104(12):5163-8. Epub 2007 Mar 2.

Department of Biochemistry, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.

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http://dx.doi.org/10.1073/pnas.0700293104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1829280PMC
March 2007

Relating protein pharmacology by ligand chemistry.

Nat Biotechnol 2007 Feb;25(2):197-206

Department of Pharmaceutical Chemistry, University of California San Francisco, 1700 4th St, San Francisco California 94143-2550, USA.

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http://dx.doi.org/10.1038/nbt1284DOI Listing
February 2007

Inositol diphosphate signaling regulates telomere length.

J Biol Chem 2005 Feb 23;280(6):4264-9. Epub 2004 Nov 23.

Departments of Pharmacology, Cancer Biology, and Biochemistry, Howard Hughes Medical Institute, Duke University Medical Center, Durham, North Carolina 27710, USA.

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http://dx.doi.org/10.1074/jbc.M412070200DOI Listing
February 2005

Mining the receptorome.

J Biol Chem 2005 Feb 8;280(7):5129-32. Epub 2004 Dec 8.

Department of Biochemistry, Case Western Reserve University School of Medicine, Cleveland, OH 44106, USA.

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http://dx.doi.org/10.1074/jbc.R400030200DOI Listing
February 2005

Rescue of an hTERT mutant defective in telomere elongation by fusion with hPot1.

Mol Cell Biol 2004 Apr;24(8):3552-61

Department of Pharmacology and Cancer Biology, Duke University Medical Center, Durham, North Carolina 27710, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC381596PMC
http://dx.doi.org/10.1128/mcb.24.8.3552-3561.2004DOI Listing
April 2004

In vivo regulation of hTERT expression and telomerase activity by androgen.

J Urol 2003 Aug;170(2 Pt 1):615-8

Department of Pharmacology, Duke University Medical Center, Durham, North Carolina 27710, USA.

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http://dx.doi.org/10.1097/01.ju.0000074653.22766.c8DOI Listing
August 2003

Putative telomere-recruiting domain in the catalytic subunit of human telomerase.

Mol Cell Biol 2003 May;23(9):3237-46

Departments of Pharmacology and Cancer Biology, Radiation Oncology, Duke University Medical Center, Durham, North Carolina 27710, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC153184PMC
http://dx.doi.org/10.1128/mcb.23.9.3237-3246.2003DOI Listing
May 2003

The nucleolar localization domain of the catalytic subunit of human telomerase.

J Biol Chem 2002 Jul 15;277(27):24764-70. Epub 2002 Apr 15.

Department of Pharmacology, Duke University Medical Center, Durham, North Carolina 27710, USA.

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http://dx.doi.org/10.1074/jbc.M201227200DOI Listing
July 2002