Publications by authors named "Bjarni V Halldórsson"

78Publications

Ratatosk: hybrid error correction of long reads enables accurate variant calling and assembly.

Authors:
Guillaume Holley Doruk Beyter Helga Ingimundardottir Peter L Møller Snædis Kristmundsdottir Hannes P Eggertsson Bjarni V Halldorsson

Genome Biol 2021 Jan 8;22(1):28. Epub 2021 Jan 8.

deCODE genetics/Amgen Inc., Reykjavík, Iceland.

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January 2021

Differences between germline genomes of monozygotic twins.

Authors:
Hakon Jonsson Erna Magnusdottir Hannes P Eggertsson Olafur A Stefansson Gudny A Arnadottir Ogmundur Eiriksson Florian Zink Einar A Helgason Ingileif Jonsdottir Arnaldur Gylfason Adalbjorg Jonasdottir Aslaug Jonasdottir Doruk Beyter Thora Steingrimsdottir Gudmundur L Norddahl Olafur Th Magnusson Gisli Masson Bjarni V Halldorsson Unnur Thorsteinsdottir Agnar Helgason Patrick Sulem Daniel F Gudbjartsson Kari Stefansson

Nat Genet 2021 Jan 7;53(1):27-34. Epub 2021 Jan 7.

deCODE genetics/Amgen, Reykjavik, Iceland.

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January 2021

Lifelong Reduction in LDL Cholesterol Due to a Gain-of-Function Mutation in .

Authors:
Eythór Björnsson Kristbjörg Gunnarsdóttir Gísli H Halldórsson Ásgeir Sigurðsson Guðný A Árnadóttir Hákon Jónsson Eva F Ólafsdóttir Sebastian Niehus Birte Kehr Garðar Sveinbjörnsson Steinunn Guðmundsdóttir Anna Helgadóttir Karl Andersen Guðmar Thorleifsson Guðmundur I Eyjólfsson Ísleifur Ólafsson Ólöf Sigurðardóttir Jóna Sæmundsdóttir Ingileif Jónsdóttir Ólafur Th Magnússon Gísli Másson Hreinn Stefánsson Daníel F Guðbjartsson Guðmundur Thorgeirsson Hilma Hólm Bjarni V Halldórsson Páll Melsted Gudmundur L Norddahl Patrick Sulem Unnur Thorsteinsdóttir Kári Stefánsson

Circ Genom Precis Med 2020 Dec 14. Epub 2020 Dec 14.

deCODE genetics/Amgen, Inc. & Faculty of Medicine, University of Iceland, Reykjavík, Iceland.

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December 2020

Read_haps: using read haplotypes to detect same species contamination in DNA sequences.

Authors:
Hannes P Eggertsson Bjarni V Halldorsson

Bioinformatics 2020 Nov 2. Epub 2020 Nov 2.

deCODE genetics, Reykjavík, 102, Iceland.

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November 2020

Sequence Variants in TAAR5 and Other Loci Affect Human Odor Perception and Naming.

Authors:
Rosa S Gisladottir Erna V Ivarsdottir Agnar Helgason Lina Jonsson Nanna K Hannesdottir Gudrun Rutsdottir Gudny A Arnadottir Astros Skuladottir Benedikt A Jonsson Gudmundur L Norddahl Magnus O Ulfarsson Hannes Helgason Bjarni V Halldorsson Muhammad S Nawaz Vinicius Tragante Gardar Sveinbjornsson Thorgeir Thorgeirsson Asmundur Oddsson Ragnar P Kristjansson Gyda Bjornsdottir Gudmundur Thorgeirsson Ingileif Jonsdottir Hilma Holm Daniel F Gudbjartsson Unnur Thorsteinsdottir Hreinn Stefansson Patrick Sulem Kari Stefansson

Curr Biol 2020 Dec 8;30(23):4643-4653.e3. Epub 2020 Oct 8.

deCODE Genetics/Amgen Inc., Sturlugata 8, 101 Reykjavik, Iceland; Faculty of Medicine, University of Iceland, Vatnsmyrarvegur 16, 101 Reykjavik, Iceland. Electronic address:

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December 2020

Genome-wide association identifies seven loci for pelvic organ prolapse in Iceland and the UK Biobank.

Authors:
Thorhildur Olafsdottir Gudmar Thorleifsson Patrick Sulem Olafur A Stefansson Helga Medek Karl Olafsson Orri Ingthorsson Valur Gudmundsson Ingileif Jonsdottir Gisli H Halldorsson Ragnar P Kristjansson Michael L Frigge Lilja Stefansdottir Jon K Sigurdsson Asmundur Oddsson Asgeir Sigurdsson Hannes P Eggertsson Pall Melsted Bjarni V Halldorsson Sigrun H Lund Unnur Styrkarsdottir Valgerdur Steinthorsdottir Julius Gudmundsson Hilma Holm Vinicius Tragante Folkert W Asselbergs Unnur Thorsteinsdottir Daniel F Gudbjartsson Kristin Jonsdottir Thorunn Rafnar Kari Stefansson

Commun Biol 2020 Mar 17;3(1):129. Epub 2020 Mar 17.

deCODE Genetics/Amgen, Sturlugata 8, 101, Reykjavik, Iceland.

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March 2020

Eighty-eight variants highlight the role of T cell regulation and airway remodeling in asthma pathogenesis.

Authors:
Thorunn A Olafsdottir Fannar Theodors Kristbjorg Bjarnadottir Unnur Steina Bjornsdottir Arna B Agustsdottir Olafur A Stefansson Erna V Ivarsdottir Jon K Sigurdsson Stefania Benonisdottir Gudmundur I Eyjolfsson David Gislason Thorarinn Gislason Steinunn Guðmundsdóttir Arnaldur Gylfason Bjarni V Halldorsson Gisli H Halldorsson Thorhildur Juliusdottir Anna M Kristinsdottir Dora Ludviksdottir Bjorn R Ludviksson Gisli Masson Kristjan Norland Pall T Onundarson Isleifur Olafsson Olof Sigurdardottir Lilja Stefansdottir Gardar Sveinbjornsson Vinicius Tragante Daniel F Gudbjartsson Gudmar Thorleifsson Patrick Sulem Unnur Thorsteinsdottir Gudmundur L Norddahl Ingileif Jonsdottir Kari Stefansson

Nat Commun 2020 01 20;11(1):393. Epub 2020 Jan 20.

deCODE genetics/Amgen, Inc., Reykjavik, Iceland.

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January 2020

Lipoprotein(a) Concentration and Risks of Cardiovascular Disease and Diabetes.

Authors:
Daniel F Gudbjartsson Gudmundur Thorgeirsson Patrick Sulem Anna Helgadottir Arnaldur Gylfason Jona Saemundsdottir Eythor Bjornsson Gudmundur L Norddahl Aslaug Jonasdottir Adalbjorg Jonasdottir Hannes P Eggertsson Solveig Gretarsdottir Gudmar Thorleifsson Olafur S Indridason Runolfur Palsson Fridbert Jonasson Ingileif Jonsdottir Gudmundur I Eyjolfsson Olof Sigurdardottir Isleifur Olafsson Ragnar Danielsen Stefan E Matthiasson Snaedis Kristmundsdottir Bjarni V Halldorsson Astradur B Hreidarsson Einar M Valdimarsson Thorarinn Gudnason Rafn Benediktsson Valgerdur Steinthorsdottir Unnur Thorsteinsdottir Hilma Holm Kari Stefansson

J Am Coll Cardiol 2019 12 9;74(24):2982-2994. Epub 2019 Dec 9.

deCODE genetics/Amgen, Reykjavik, Iceland; Faculty of Medicine, School of Health Sciences, University of Iceland, Reykjavik, Iceland. Electronic address:

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December 2019

popSTR2 enables clinical and population-scale genotyping of microsatellites.

Authors:
Snædis Kristmundsdottir Hannes P Eggertsson Gudny A Arnadottir Bjarni V Halldorsson

Bioinformatics 2020 04;36(7):2269-2271

deCODE genetics/Amgen, Reykjavík 102, Iceland.

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April 2020

GraphTyper2 enables population-scale genotyping of structural variation using pangenome graphs.

Authors:
Hannes P Eggertsson Snaedis Kristmundsdottir Doruk Beyter Hakon Jonsson Astros Skuladottir Marteinn T Hardarson Daniel F Gudbjartsson Kari Stefansson Bjarni V Halldorsson Pall Melsted

Nat Commun 2019 11 27;10(1):5402. Epub 2019 Nov 27.

deCODE genetics/Amgen Inc., Sturlugata 8, Reykjavik, Iceland.

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November 2019

Clinical decision support system for the management of osteoporosis compared to NOGG guidelines and an osteology specialist: a validation pilot study.

Authors:
Haukur T Gudmundsson Karen E Hansen Bjarni V Halldorsson Bjorn R Ludviksson Bjorn Gudbjornsson

BMC Med Inform Decis Mak 2019 02 1;19(1):27. Epub 2019 Feb 1.

Landspitali - University Hospital, Reykjavik, Iceland.

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February 2019

Characterizing mutagenic effects of recombination through a sequence-level genetic map.

Authors:
Bjarni V Halldorsson Gunnar Palsson Olafur A Stefansson Hakon Jonsson Marteinn T Hardarson Hannes P Eggertsson Bjarni Gunnarsson Asmundur Oddsson Gisli H Halldorsson Florian Zink Sigurjon A Gudjonsson Michael L Frigge Gudmar Thorleifsson Asgeir Sigurdsson Simon N Stacey Patrick Sulem Gisli Masson Agnar Helgason Daniel F Gudbjartsson Unnur Thorsteinsdottir Kari Stefansson

Science 2019 Jan;363(6425)

deCODE genetics, Amgen, Sturlugata 8, Reykjavik, Iceland.

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January 2019

A loss-of-function variant in ALOX15 protects against nasal polyps and chronic rhinosinusitis.

Authors:
Ragnar P Kristjansson Stefania Benonisdottir Olafur B Davidsson Asmundur Oddsson Vinicius Tragante Jon K Sigurdsson Lilja Stefansdottir Stefan Jonsson Brynjar O Jensson Joseph G Arthur Gudny A Arnadottir Gerald Sulem Bjarni V Halldorsson Bjarni Gunnarsson Gisli H Halldorsson Olafur A Stefansson Gudjon R Oskarsson Aimee M Deaton Isleifur Olafsson Gudmundur I Eyjolfsson Olof Sigurdardottir Pall T Onundarson David Gislason Thorarinn Gislason Bjorn R Ludviksson Dora Ludviksdottir Thorunn A Olafsdottir Thorunn Rafnar Gisli Masson Florian Zink Gyda Bjornsdottir Olafur Th Magnusson Unnur S Bjornsdottir Gudmar Thorleifsson Gudmundur L Norddahl Daniel F Gudbjartsson Unnur Thorsteinsdottir Ingileif Jonsdottir Patrick Sulem Kari Stefansson

Nat Genet 2019 02 14;51(2):267-276. Epub 2019 Jan 14.

deCODE genetics/Amgen Inc., Reykjavik, Iceland.

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February 2019

Sequence variants associating with urinary biomarkers.

Authors:
Stefania Benonisdottir Ragnar P Kristjansson Asmundur Oddsson Valgerdur Steinthorsdottir Evgenia Mikaelsdottir Birte Kehr Brynjar O Jensson Gudny A Arnadottir Gerald Sulem Gardar Sveinbjornsson Snaedis Kristmundsdottir Erna V Ivarsdottir Vinicius Tragante Bjarni Gunnarsson Hrafnhildur Linnet Runolfsdottir Joseph G Arthur Aimee M Deaton Gudmundur I Eyjolfsson Olafur B Davidsson Folkert W Asselbergs Astradur B Hreidarsson Thorunn Rafnar Gudmar Thorleifsson Vidar Edvardsson Gunnar Sigurdsson Anna Helgadottir Bjarni V Halldorsson Gisli Masson Hilma Holm Pall T Onundarson Olafur S Indridason Rafn Benediktsson Runolfur Palsson Daniel F Gudbjartsson Isleifur Olafsson Unnur Thorsteinsdottir Patrick Sulem Kari Stefansson

Hum Mol Genet 2019 04;28(7):1199-1211

deCODE genetics/Amgen Inc., Reykjavik, Iceland.

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April 2019

Multiple transmissions of de novo mutations in families.

Authors:
Hákon Jónsson Patrick Sulem Gudny A Arnadottir Gunnar Pálsson Hannes P Eggertsson Snaedis Kristmundsdottir Florian Zink Birte Kehr Kristjan E Hjorleifsson Brynjar Ö Jensson Ingileif Jonsdottir Sigurdur Einar Marelsson Sigurjon Axel Gudjonsson Arnaldur Gylfason Adalbjorg Jonasdottir Aslaug Jonasdottir Simon N Stacey Olafur Th Magnusson Unnur Thorsteinsdottir Gisli Masson Augustine Kong Bjarni V Halldorsson Agnar Helgason Daniel F Gudbjartsson Kari Stefansson

Nat Genet 2018 12 5;50(12):1674-1680. Epub 2018 Nov 5.

deCODE genetics/Amgen Inc., Reykjavik, Iceland.

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December 2018

Insights into imprinting from parent-of-origin phased methylomes and transcriptomes.

Authors:
Florian Zink Droplaug N Magnusdottir Olafur T Magnusson Nicolas J Walker Tiffany J Morris Asgeir Sigurdsson Gisli H Halldorsson Sigurjon A Gudjonsson Pall Melsted Helga Ingimundardottir Snædis Kristmundsdottir Kristjan F Alexandersson Anna Helgadottir Julius Gudmundsson Thorunn Rafnar Ingileif Jonsdottir Hilma Holm Gudmundur Ingi Eyjolfsson Olof Sigurdardottir Isleifur Olafsson Gisli Masson Daniel F Gudbjartsson Unnur Thorsteinsdottir Bjarni V Halldorsson Simon N Stacey Kari Stefansson

Nat Genet 2018 11 22;50(11):1542-1552. Epub 2018 Oct 22.

deCODE genetics/AMGEN, Reykjavik, Iceland.

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November 2018

Identification of Lynch syndrome risk variants in the Romanian population.

Authors:
Paul D Iordache Dana Mates Bjarni Gunnarsson Hannes P Eggertsson Patrick Sulem Stefania Benonisdottir Irma Eva Csiki Stefan Rascu Daniel Radavoi Radu Ursu Catalin Staicu Violeta Calota Angelica Voinoiu Mariana Jinga Gabriel Rosoga Razvan Danau Sorin Cristian Sima Daniel Badescu Nicoleta Suciu Viorica Radoi Ioan Nicolae Mates Mihai Dobra Camelia Nicolae Sigrun Kristjansdottir Jon G Jonasson Andrei Manolescu Gudny Arnadottir Brynjar Jensson Aslaug Jonasdottir Asgeir Sigurdsson Louise le Roux Hrefna Johannsdottir Thorunn Rafnar Bjarni V Halldorsson Viorel Jinga Kari Stefansson

J Cell Mol Med 2018 12 16;22(12):6068-6076. Epub 2018 Oct 16.

deCODE genetics/AMGEN, Reykjavik, Iceland.

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December 2018

Coding variants in and increase risk of atrial fibrillation.

Authors:
Rosa B Thorolfsdottir Gardar Sveinbjornsson Patrick Sulem Jonas B Nielsen Stefan Jonsson Gisli H Halldorsson Pall Melsted Erna V Ivarsdottir Olafur B Davidsson Ragnar P Kristjansson Gudmar Thorleifsson Anna Helgadottir Solveig Gretarsdottir Gudmundur Norddahl Sridharan Rajamani Bjarni Torfason Atli S Valgardsson Jon T Sverrisson Vinicius Tragante Oddgeir L Holmen Folkert W Asselbergs Dan M Roden Dawood Darbar Terje R Pedersen Marc S Sabatine Cristen J Willer Maja-Lisa Løchen Bjarni V Halldorsson Ingileif Jonsdottir Kristian Hveem David O Arnar Unnur Thorsteinsdottir Daniel F Gudbjartsson Hilma Holm Kari Stefansson

Commun Biol 2018 12;1:68. Epub 2018 Jun 12.

deCODE genetics/Amgen, Inc., Reykjavik, Iceland.

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June 2018

Author Correction: The rate of meiotic gene conversion varies by sex and age.

Authors:
Bjarni V Halldorsson Marteinn T Hardarson Birte Kehr Unnur Styrkarsdottir Arnaldur Gylfason Gudmar Thorleifsson Florian Zink Adalbjorg Jonasdottir Aslaug Jonasdottir Patrick Sulem Gisli Masson Unnur Thorsteinsdottir Agnar Helgason Augustine Kong Daniel F Gudbjartsson Kari Stefansson

Nat Genet 2018 11;50(11):1616

deCODE Genetics/Amgen, Inc., Reykjavik, Iceland.

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November 2018

Variants associating with uterine leiomyoma highlight genetic background shared by various cancers and hormone-related traits.

Authors:
Thorunn Rafnar Bjarni Gunnarsson Olafur A Stefansson Patrick Sulem Andres Ingason Michael L Frigge Lilja Stefansdottir Jon K Sigurdsson Vinicius Tragante Valgerdur Steinthorsdottir Unnur Styrkarsdottir Simon N Stacey Julius Gudmundsson Gudny A Arnadottir Asmundur Oddsson Florian Zink Gisli Halldorsson Gardar Sveinbjornsson Ragnar P Kristjansson Olafur B Davidsson Anna Salvarsdottir Asgeir Thoroddsen Elisabet A Helgadottir Katrin Kristjansdottir Orri Ingthorsson Valur Gudmundsson Reynir T Geirsson Ragnheidur Arnadottir Daniel F Gudbjartsson Gisli Masson Folkert W Asselbergs Jon G Jonasson Karl Olafsson Unnur Thorsteinsdottir Bjarni V Halldorsson Gudmar Thorleifsson Kari Stefansson

Nat Commun 2018 09 7;9(1):3636. Epub 2018 Sep 7.

deCODE Genetics/Amgen, Sturlugata 8, 101, Reykjavik, Iceland.

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September 2018