Bjarni J Vilhjalmsson

Bjarni J Vilhjalmsson

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Bjarni J Vilhjalmsson

Bjarni J Vilhjalmsson

Publications by authors named "Bjarni J Vilhjalmsson"

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26Publications

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Making the Most of Clumping and Thresholding for Polygenic Scores.

Am J Hum Genet 2019 Dec 21;105(6):1213-1221. Epub 2019 Nov 21.

Laboratoire TIMC-IMAG, UMR 5525, Univ. Grenoble Alpes, CNRS, La Tronche, France. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2019.11.001DOI Listing
December 2019

Association Mapping and Disease: Evolutionary Perspectives.

Methods Mol Biol 2019 ;1910:533-553

Bioinformatics Research Centre, Aarhus University, Aarhus, Denmark.

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http://link.springer.com/10.1007/978-1-4939-9074-0_17
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http://dx.doi.org/10.1007/978-1-4939-9074-0_17DOI Listing
January 2019

Nationwide Genomic Study in Denmark Reveals Remarkable Population Homogeneity.

Genetics 2016 Oct 17;204(2):711-722. Epub 2016 Aug 17.

Bioinformatics Research Centre, Aarhus University, 8000, Denmark Centre for Biocultural History, Aarhus University, 8000, Denmark.

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http://dx.doi.org/10.1534/genetics.116.189241DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5068857PMC
October 2016

Response to Day et al.

Am J Hum Genet 2016 Feb;98(2):394-5

Department of Epidemiology, Harvard T.H. Chan School of Public Health, Harvard University, Boston, MA 02115, USA; Program in Genetic Epidemiology and Statistical Genetics, Harvard T.H. Chan School of Public Health, Harvard University, Boston, MA 02115, USA.

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http://dx.doi.org/10.1016/j.ajhg.2015.12.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4746361PMC
February 2016

Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores.

Am J Hum Genet 2015 Oct;97(4):576-92

Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA; Program in Genetic Epidemiology and Statistical Genetics, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA; Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA. Electronic address:

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http://biorxiv.org/content/biorxiv/early/2015/03/01/015859.f
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http://linkinghub.elsevier.com/retrieve/pii/S000292971500365
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http://dx.doi.org/10.1016/j.ajhg.2015.09.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4596916PMC
October 2015

Polygenic Risk Score, Parental Socioeconomic Status, Family History of Psychiatric Disorders, and the Risk for Schizophrenia: A Danish Population-Based Study and Meta-analysis.

JAMA Psychiatry 2015 Jul;72(7):635-41

Lundbeck Foundation Initiative for Integrative Psychiatric Research, Aarhus, Denmark2National Centre for Register-Based Research, Aarhus University, Aarhus, Denmark3Centre for Integrated Register-Based Research, Aarhus University, Aarhus, Denmark.

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http://dx.doi.org/10.1001/jamapsychiatry.2015.0346DOI Listing
July 2015

Efficient Bayesian mixed-model analysis increases association power in large cohorts.

Nat Genet 2015 Mar 2;47(3):284-90. Epub 2015 Feb 2.

1] Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA. [2] Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA. [3] Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1038/ng.3190DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4342297PMC
March 2015

Adjusting for heritable covariates can bias effect estimates in genome-wide association studies.

Am J Hum Genet 2015 Feb 29;96(2):329-39. Epub 2015 Jan 29.

Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA.

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http://dx.doi.org/10.1016/j.ajhg.2014.12.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4320269PMC
February 2015

Quantifying missing heritability at known GWAS loci.

PLoS Genet 2013 26;9(12):e1003993. Epub 2013 Dec 26.

Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, United States of America ; Department of Biostatistics, Harvard School of Public Health, Boston, Massachusetts, United States of America ; Medical and Population Genetics Program, Broad Institute, Cambridge, Massachusetts, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1003993DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3873246PMC
August 2014

Maximizing the power of principal-component analysis of correlated phenotypes in genome-wide association studies.

Am J Hum Genet 2014 May 17;94(5):662-76. Epub 2014 Apr 17.

Program in Genetic Epidemiology and Statistical Genetics, Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S00029297140011
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http://dx.doi.org/10.1016/j.ajhg.2014.03.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4067564PMC
May 2014

JAWAMix5: an out-of-core HDF5-based java implementation of whole-genome association studies using mixed models.

Bioinformatics 2013 May 11;29(9):1220-2. Epub 2013 Mar 11.

Gregor Mendel Institute, Austrian Academy of Sciences, Vienna 1030, Austria.

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http://dx.doi.org/10.1093/bioinformatics/btt122DOI Listing
May 2013

The nature of confounding in genome-wide association studies.

Nat Rev Genet 2013 Jan 20;14(1):1-2. Epub 2012 Nov 20.

Harvard School of Public Health, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1038/nrg3382DOI Listing
January 2013

GWAPP: a web application for genome-wide association mapping in Arabidopsis.

Plant Cell 2012 Dec 31;24(12):4793-805. Epub 2012 Dec 31.

Gregor Mendel Institute, Austrian Academy of Sciences, 1030, Viena, Austria.

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http://dx.doi.org/10.1105/tpc.112.108068DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3556958PMC
December 2012

Conditions under which genome-wide association studies will be positively misleading.

Genetics 2010 Nov 2;186(3):1045-52. Epub 2010 Sep 2.

Molecular and Computational Biology, University of Southern California, Los Angeles, California 90089, USA.

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http://www.genetics.org/cgi/doi/10.1534/genetics.110.121665
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http://dx.doi.org/10.1534/genetics.110.121665DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2975277PMC
November 2010