Birgit Strobl

Birgit Strobl

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Birgit Strobl

Birgit Strobl

Publications by authors named "Birgit Strobl"

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Type I Interferon Response Dysregulates Host Iron Homeostasis and Enhances Candida glabrata Infection.

Cell Host Microbe 2020 Mar 18;27(3):454-466.e8. Epub 2020 Feb 18.

Medical University of Vienna, Center for Medical Biochemistry, Max Perutz Labs Vienna, Campus Vienna Biocenter, 1030 Vienna, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.chom.2020.01.023DOI Listing
March 2020

TYK2 in Tumor Immunosurveillance.

Cancers (Basel) 2020 Jan 8;12(1). Epub 2020 Jan 8.

Institute of Animal Breeding and Genetics, University of Veterinary Medicine Vienna, A-1210 Vienna, Austria.

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http://dx.doi.org/10.3390/cancers12010150DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7017180PMC
January 2020

TYK2: An Upstream Kinase of STATs in Cancer.

Cancers (Basel) 2019 Nov 5;11(11). Epub 2019 Nov 5.

Institute of Animal Breeding and Genetics, University of Veterinary Medicine Vienna, A-1210 Vienna, Austria.

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http://dx.doi.org/10.3390/cancers11111728DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6896190PMC
November 2019

The C-Terminal Transactivation Domain of STAT1 Has a Gene-Specific Role in Transactivation and Cofactor Recruitment.

Front Immunol 2018 6;9:2879. Epub 2018 Dec 6.

Department of Biomedical Sciences, Institute of Animal Breeding and Genetics, University of Veterinary Medicine Vienna, Vienna, Austria.

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http://dx.doi.org/10.3389/fimmu.2018.02879DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6291510PMC
October 2019

NK Cells Require Cell-Extrinsic and -Intrinsic TYK2 for Full Functionality in Tumor Surveillance and Antibacterial Immunity.

J Immunol 2019 03 4;202(6):1724-1734. Epub 2019 Feb 4.

Department of Biomedical Science, Institute of Animal Breeding and Genetics, University of Veterinary Medicine Vienna, 1210 Vienna, Austria;

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http://dx.doi.org/10.4049/jimmunol.1701649DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6398083PMC
March 2019

Metabolic Regulators Nampt and Sirt6 Serially Participate in the Macrophage Interferon Antiviral Cascade.

Front Microbiol 2019 4;10:355. Epub 2019 Mar 4.

Systems Immunity Research Institute, School of Medicine, Cardiff University, Cardiff, United Kingdom.

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http://dx.doi.org/10.3389/fmicb.2019.00355DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6409323PMC
March 2019

Tyrosine kinase 2 - Surveillant of tumours and bona fide oncogene.

Cytokine 2017 01 26;89:209-218. Epub 2015 Nov 26.

Institute of Animal Breeding and Genetics, University of Veterinary Medicine Vienna, Veterinärplatz 1, 1210 Vienna, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.cyto.2015.10.015DOI Listing
January 2017

The good and the bad faces of STAT1 in solid tumours.

Cytokine 2017 01 26;89:12-20. Epub 2015 Nov 26.

Institute of Animal Breeding and Genetics, University of Veterinary Medicine Vienna, Veterinärplatz 1, 1210 Vienna, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.cyto.2015.11.011DOI Listing
January 2017

Kinase Inactive Tyrosine Kinase (Tyk2) Supports Differentiation of Brown Fat Cells.

Endocrinology 2017 01;158(1):148-157

Department of Biochemistry and Molecular Biology, and Massey Cancer Center, Virginia Commonwealth University, Richmond, Virginia 23298.

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http://dx.doi.org/10.1210/en.2015-2048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5412977PMC
January 2017

Defining the functional binding sites of interleukin 12 receptor β1 and interleukin 23 receptor to Janus kinases.

Mol Biol Cell 2016 07 18;27(14):2301-16. Epub 2016 May 18.

Institute of Biochemistry and Molecular Biology II, Medical Faculty, Heinrich-Heine-University, D-40225 Düsseldorf, Germany

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http://dx.doi.org/10.1091/mbc.E14-12-1645DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4945146PMC
July 2016

Intestinal Microbiota Signatures Associated with Inflammation History in Mice Experiencing Recurring Colitis.

Front Microbiol 2015 15;6:1408. Epub 2015 Dec 15.

Division of Microbial Ecology, Department of Microbiology and Ecosystem Science, Research Network Chemistry meets Microbiology, University of Vienna Vienna, Austria.

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http://dx.doi.org/10.3389/fmicb.2015.01408DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4678223PMC
December 2015

tumor surveillance by NK cells requires TYK2 but not TYK2 kinase activity.

Oncoimmunology 2015 Nov 26;4(11):e1047579. Epub 2015 May 26.

Institute of Animal Breeding and Genetics; University of Veterinary Medicine ; Vienna, Austria.

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http://dx.doi.org/10.1080/2162402X.2015.1047579DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4589058PMC
November 2015

Methods to study tumor surveillance using tumor cell transplantation into genetically engineered mice.

Methods Mol Biol 2015 ;1267:439-56

Ludwig Boltzmann Institute for Cancer Research, Vienna, Austria.

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http://dx.doi.org/10.1007/978-1-4939-2297-0_22DOI Listing
September 2015

Noncanonical Effects of IRF9 in Intestinal Inflammation: More than Type I and Type III Interferons.

Mol Cell Biol 2015 Jul 27;35(13):2332-43. Epub 2015 Apr 27.

Department of Microbiology and Immunobiology, Max F. Perutz Laboratories, University of Vienna, Vienna, Austria

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http://dx.doi.org/10.1128/MCB.01498-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4456449PMC
July 2015

Promoter occupancy of STAT1 in interferon responses is regulated by processive transcription.

Mol Cell Biol 2015 Feb 15;35(4):716-27. Epub 2014 Dec 15.

Max F. Perutz Laboratories, University of Vienna, Vienna, Austria

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http://dx.doi.org/10.1128/MCB.01097-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4301719PMC
February 2015

Loss of STAT3 in murine NK cells enhances NK cell-dependent tumor surveillance.

Blood 2014 Oct 2;124(15):2370-9. Epub 2014 Sep 2.

Institute of Pharmacology and Toxicology, Department for Biomedical Sciences, and.

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http://dx.doi.org/10.1182/blood-2014-03-564450DOI Listing
October 2014

Inducible, dose-adjustable and time-restricted reconstitution of STAT1 deficiency in vivo.

PLoS One 2014 29;9(1):e86608. Epub 2014 Jan 29.

Institute of Animal Breeding and Genetics, University of Veterinary Medicine Vienna, Vienna, Austria ; University Center Biomodels Austria (BIAT), University of Veterinary Medicine Vienna, Vienna, Austria.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0086608PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3906053PMC
September 2014

Type I interferons have opposing effects during the emergence and recovery phases of colitis.

Eur J Immunol 2014 Sep 25;44(9):2749-60. Epub 2014 Aug 25.

Max F. Perutz Laboratories, Department of Microbiology, Immunobiology and Genetics, University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.1002/eji.201344401DOI Listing
September 2014

Tyrosine kinase 2 promotes sepsis-associated lethality by facilitating production of interleukin-27.

J Leukoc Biol 2014 Jul 6;96(1):123-31. Epub 2014 Mar 6.

Department of Pathology, University of Michigan Medical School, Ann Arbor, Michigan, USA; and.

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http://dx.doi.org/10.1189/jlb.3A1013-541RDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4056273PMC
July 2014

Conditional ablation of TYK2 in immunity to viral infection and tumor surveillance.

Transgenic Res 2014 Jun 3;23(3):519-29. Epub 2014 Apr 3.

Institute of Animal Breeding and Genetics, University of Veterinary Medicine, Veterinärplatz 1, 1210, Vienna, Austria.

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http://dx.doi.org/10.1007/s11248-014-9795-yDOI Listing
June 2014

Recovery from chemotherapy depends on STAT1 for replenishment of B lymphopoiesis.

J Leukoc Biol 2014 Jun;95(6):849-51

Institute of Animal Breeding and Genetics, University of Veterinary Medicine Vienna, Austria; and Ludwig Boltzmann Institute for Cancer Research and Medical University of Vienna, Austria

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http://dx.doi.org/10.1189/jlb.0114051DOI Listing
June 2014

Longitudinal study of murine microbiota activity and interactions with the host during acute inflammation and recovery.

ISME J 2014 May 9;8(5):1101-14. Epub 2014 Jan 9.

Division of Archaea Biology and Ecogenomics, Department of Ecogenomics and Systems Biology, Faculty of Life Sciences, University of Vienna, Wien, Austria.

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http://dx.doi.org/10.1038/ismej.2013.223DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3996699PMC
May 2014

Important scaffold function of the Janus kinase 2 uncovered by a novel mouse model harboring a Jak2 activation-loop mutation.

Blood 2014 Jan 29;123(4):520-9. Epub 2013 Oct 29.

Institute of Medical Microbiology and Hospital Hygiene, University of Düsseldorf, Düsseldorf, Germany;

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http://dx.doi.org/10.1182/blood-2013-03-492157DOI Listing
January 2014

Tyrosine kinase 2 (TYK2) in cytokine signalling and host immunity.

Front Biosci (Landmark Ed) 2011 Jun 1;16:3214-32. Epub 2011 Jun 1.

Institute of Animal Breeding and Genetics, University of Veterinary Medicine Vienna, Veterinaerplatz 1, 1210 Vienna, Austria.

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http://dx.doi.org/10.2741/3908DOI Listing
June 2011

Tyrosine kinase 2 controls IL-1ß production at the translational level.

J Immunol 2010 Sep 16;185(6):3544-53. Epub 2010 Aug 16.

Institute of Animal Breeding and Genetics, University of Veterinary Medicine Vienna, Vienna, Austria.

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http://dx.doi.org/10.4049/jimmunol.0904000DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2990881PMC
September 2010

Octamer-binding factor 6 (Oct-6/Pou3f1) is induced by interferon and contributes to dsRNA-mediated transcriptional responses.

BMC Cell Biol 2010 Aug 5;11:61. Epub 2010 Aug 5.

Institute of Animal Breeding and Genetics, University of Veterinary Medicine Vienna, Vienna, Austria.

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http://dx.doi.org/10.1186/1471-2121-11-61DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2924845PMC
August 2010

Transcriptome analysis reveals a major impact of JAK protein tyrosine kinase 2 (Tyk2) on the expression of interferon-responsive and metabolic genes.

BMC Genomics 2010 Mar 25;11:199. Epub 2010 Mar 25.

Institute of Animal Breeding and Genetics, Department of Biomedical Sciences, University of Veterinary Medicine Vienna, Veterinärplatz 1, A-1210 Vienna, Austria.

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http://dx.doi.org/10.1186/1471-2164-11-199DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2864243PMC
March 2010

Type I interferons as mediators of immune adjuvants for T- and B cell-dependent acquired immunity.

Vaccine 2009 Dec;27 Suppl 6:G17-20

Department of Pharmacology, Medical University of Vienna, Austria; Institute of Animal Breeding and Genetics, University of Veterinary Medicine, Vienna, Austria.

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https://linkinghub.elsevier.com/retrieve/pii/S0264410X090153
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http://dx.doi.org/10.1016/j.vaccine.2009.10.016DOI Listing
December 2009

Tyk2 and signal transducer and activator of transcription 1 contribute to intestinal I/R injury.

Shock 2008 Feb;29(2):238-44

Institute of Animal Breeding and Genetics, University of Veterinary Medicine, Vienna, Austria.

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http://dx.doi.org/10.1097/SHK.0b013e3180cab252DOI Listing
February 2008

A time- and dose-dependent STAT1 expression system.

BMC Biotechnol 2006 Dec 21;6:48. Epub 2006 Dec 21.

Institute of Animal Breeding and Genetics, Veterinary University of Vienna, Veterinärplatz 1, 1210 Vienna, Austria.

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http://dx.doi.org/10.1186/1472-6750-6-48DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1770918PMC
December 2006

Contribution of cell culture additives to the two-dimensional protein patterns of mouse macrophages.

Electrophoresis 2006 Apr;27(8):1626-9

Institute of Medical Chemistry, University of Veterinary Medicine, Vienna, Austria.

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http://doi.wiley.com/10.1002/elps.200500744
Publisher Site
http://dx.doi.org/10.1002/elps.200500744DOI Listing
April 2006

Studying human pathogens in animal models: fine tuning the humanized mouse.

Transgenic Res 2005 Dec;14(6):803-6

Department of Agrobiotechnology, IFA-Tulln, Institute of Biotechnology in Animal Production, University of Natural Resources and Applied Life Sciences, Austria.

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http://dx.doi.org/10.1007/s11248-005-1676-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7088949PMC
December 2005

Novel functions of tyrosine kinase 2 in the antiviral defense against murine cytomegalovirus.

J Immunol 2005 Sep;175(6):4000-8

Institute of Animal Breeding and Genetics, Veterinary University of Vienna, Vienna, Austria.

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http://dx.doi.org/10.4049/jimmunol.175.6.4000DOI Listing
September 2005

Recombinant viral sialate-O-acetylesterases.

Glycoconj J 2004 ;20(9):551-61

Applied Biotechnology, Department of Cell Biology, University Salzburg, A-5020 Salzburg, Austria.

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http://dx.doi.org/10.1023/B:GLYC.0000043292.64358.f1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7087582PMC
March 2005

Evaluation of the ankle syndesmosis: a plastination slices study.

Clin Anat 2004 Sep;17(6):513-7

Plastination Laboratory, Institute of Anatomy, Vienna University, Vienna, Austria.

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http://dx.doi.org/10.1002/ca.20019DOI Listing
September 2004

The STAT3 isoforms alpha and beta have unique and specific functions.

Nat Immunol 2004 Apr 14;5(4):401-9. Epub 2004 Mar 14.

Department of Genetics, Biology and Biochemistry, University of Turin, 10126 Turin, Italy.

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http://www.nature.com/articles/ni1052
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http://dx.doi.org/10.1038/ni1052DOI Listing
April 2004

Of JAKs, STATs, blind watchmakers, jeeps and trains.

FEBS Lett 2003 Jul;546(1):1-5

Cancer Research UK London Research Institute, Lincoln's Inn Laboratories, 44 Lincoln's Inn Fields, London WC2A 3PX, UK.

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http://dx.doi.org/10.1016/s0014-5793(03)00411-3DOI Listing
July 2003

Cell-type and donor-specific transcriptional responses to interferon-alpha. Use of customized gene arrays.

J Biol Chem 2002 Dec 16;277(51):49428-37. Epub 2002 Oct 16.

Cancer Research UK, London Research Institute, 44 Lincoln's Inn Fields, London WC2A 3PX, UK.

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http://dx.doi.org/10.1074/jbc.M205571200DOI Listing
December 2002

Aortic arch variation analyzed by using plastination.

Clin Anat 2002 Nov;15(6):379-82

Plastination Laboratory, Institute of Anatomy, Vienna University, Vienna, Austria.

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http://dx.doi.org/10.1002/ca.10059DOI Listing
November 2002

The antiviral response to gamma interferon.

J Virol 2002 Sep;76(18):9060-8

Cancer Research UK London Research Institute, London WC2A 3PX, United Kingdom.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC136459PMC
http://dx.doi.org/10.1128/jvi.76.18.9060-9068.2002DOI Listing
September 2002

Mutational switch of an IL-6 response to an interferon-gamma-like response.

Proc Natl Acad Sci U S A 2002 Jun;99(12):8043-7

Cancer Research United Kingdom London Research Institute, 44 Lincoln's Inn Fields, London WC2A 3PX, United Kingdom.

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http://dx.doi.org/10.1073/pnas.122236099DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC123017PMC
June 2002

Release of toxic metals from button batteries retained in the stomach: An in vitro study.

J Pediatr Surg 2002 Jan;37(1):87-92

Department of Paediatrics, Royal Aberdeen Children's Hospital, Foresterhill, Aberdeen, Scotland.

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http://dx.doi.org/10.1053/jpsu.2002.29435DOI Listing
January 2002