Birgit Schilling

Birgit Schilling

UNVERIFIED PROFILE

Are you Birgit Schilling?   Register this Author

Register author
Birgit Schilling

Birgit Schilling

Publications by authors named "Birgit Schilling"

Are you Birgit Schilling?   Register this Author

98Publications

2612Reads

46Profile Views

Sirtuin 5 Regulates Proximal Tubule Fatty Acid Oxidation to Protect against AKI.

J Am Soc Nephrol 2019 Oct 1. Epub 2019 Oct 1.

Department of Pediatrics, University of Pittsburgh School of Medicine, University of Pittsburgh Medical Center Children's Hospital of Pittsburgh, University of Pittsburgh, Pittsburgh, Pennsylvania; and

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1681/ASN.2019020163DOI Listing
October 2019

Accumulation of "Old Proteins" and the Critical Need for MS-based Protein Turnover Measurements in Aging and Longevity.

Proteomics 2019 Aug 13:e1800403. Epub 2019 Aug 13.

The Buck Institute for Research on Aging, Novato, CA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/pmic.201800403DOI Listing
August 2019

Post-translational Protein Acetylation: An Elegant Mechanism for Bacteria to Dynamically Regulate Metabolic Functions.

Front Microbiol 2019 12;10:1604. Epub 2019 Jul 12.

Health Sciences Division, Department of Microbiology and Immunology, Stritch School of Medicine, Loyola University Chicago, Maywood, IL, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fmicb.2019.01604DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6640162PMC
July 2019

Global Lysine Acetylation in Results from Growth Conditions That Favor Acetate Fermentation.

J Bacteriol 2019 May 9;201(9). Epub 2019 Apr 9.

Department of Chemical and Biomolecular Engineering, University of Illinois at Urbana-Champaign, Urbana, Illinois, USA

View Article

Download full-text PDF

Source
http://jb.asm.org/lookup/doi/10.1128/JB.00768-18
Publisher Site
http://dx.doi.org/10.1128/JB.00768-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456854PMC
May 2019

Regulation of UCP1 and Mitochondrial Metabolism in Brown Adipose Tissue by Reversible Succinylation.

Mol Cell 2019 05 15;74(4):844-857.e7. Epub 2019 Apr 15.

Section on Integrative Physiology and Metabolism, Joslin Diabetes Center, Harvard Medical School, Boston, MA 02215, USA. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S10972765193022
Publisher Site
http://dx.doi.org/10.1016/j.molcel.2019.03.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6525068PMC
May 2019

Correction for Christensen et al., "Identification of Novel Protein Lysine Acetyltransferases in Escherichia coli".

MBio 2019 04 9;10(2). Epub 2019 Apr 9.

Department of Microbiology and Immunology, Stritch School of Medicine, Health Sciences Division, Loyola University Chicago, Maywood, Illinois, USA

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/mBio.00592-19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456757PMC
April 2019

High-Resolution Mass Spectrometry to Identify and Quantify Acetylation Protein Targets.

Methods Mol Biol 2019 ;1983:3-16

Buck Institute for Research on Aging, Novato, CA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/978-1-4939-9434-2_1DOI Listing
January 2019

Impairment of Angiogenesis by Fatty Acid Synthase Inhibition Involves mTOR Malonylation.

Cell Metab 2018 12 23;28(6):866-880.e15. Epub 2018 Aug 23.

Laboratory of Angiogenesis and Vascular Metabolism, VIB Center for Cancer Biology (CCB), VIB, 3000 Leuven, Belgium; State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangzhou 510060, Guangdong, P.R. China; Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology and Leuven Cancer Institute (LKI), KU Leuven, 3000 Leuven, Belgium. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S15504131183046
Publisher Site
http://dx.doi.org/10.1016/j.cmet.2018.07.019DOI Listing
December 2018

Identifying ubiquitinated proteins and aggregates.

Aging (Albany NY) 2018 10;10(10):2549-2550

Department of Pathology, University of Washington, Seattle, WA 98105, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.18632/aging.101605DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224256PMC
October 2018

Identification of Novel Protein Lysine Acetyltransferases in Escherichia coli.

MBio 2018 10 23;9(5). Epub 2018 Oct 23.

Department of Microbiology and Immunology, Stritch School of Medicine, Health Sciences Division, Loyola University Chicago, Maywood, Illinois, USA

View Article

Download full-text PDF

Source
http://mbio.asm.org/lookup/doi/10.1128/mBio.01905-18
Publisher Site
http://dx.doi.org/10.1128/mBio.01905-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199490PMC
October 2018

Simultaneous Quantification of the Acetylome and Succinylome by 'One-Pot' Affinity Enrichment.

Proteomics 2018 09 19;18(17):e1800123. Epub 2018 Aug 19.

The Buck Institute for Research on Aging, 94945 Novato, CA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/pmic.201800123DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175148PMC
September 2018

Panorama Public: A Public Repository for Quantitative Data Sets Processed in Skyline.

Mol Cell Proteomics 2018 06 27;17(6):1239-1244. Epub 2018 Feb 27.

From the ‡University of Washington, Seattle, Washington 98195;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/mcp.RA117.000543DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5986241PMC
June 2018

Removing 4E-BP Enables Synapses to Refine without Postsynaptic Activity.

Cell Rep 2018 04;23(1):11-22

Department of Physiology, McGill University, Montreal, QC H3G 1Y6, Canada; Buck Institute for Research on Aging, Novato, CA 94945, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.celrep.2018.03.040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6483372PMC
April 2018

Protein Turnover in Aging and Longevity.

Proteomics 2018 03;18(5-6):e1700108

The Buck Institute for Research on Aging, Novato, CA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/pmic.201700108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6022828PMC
March 2018

An acetylatable lysine controls CRP function in E. coli.

Mol Microbiol 2018 Jan 23;107(1):116-131. Epub 2017 Nov 23.

Department of Microbiology and Immunology, Stritch School of Medicine, Health Sciences Division, Loyola University Chicago, Maywood, IL, 60153, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/mmi.13874DOI Listing
January 2018

MSstatsQC: Longitudinal System Suitability Monitoring and Quality Control for Targeted Proteomic Experiments.

Mol Cell Proteomics 2017 07 8;16(7):1335-1347. Epub 2017 May 8.

From the ‡College of Computer and Information Science, Northeastern University, Massachusetts 02115;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/mcp.M116.064774DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5500765PMC
July 2017

Clinical applications of quantitative proteomics using targeted and untargeted data-independent acquisition techniques.

Expert Rev Proteomics 2017 05;14(5):419-429

a Mass Spectrometry Core , Buck Institute for Research on Aging , Novato , CA , USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/14789450.2017.1322904DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5671767PMC
May 2017

Acetylated Tau Obstructs KIBRA-Mediated Signaling in Synaptic Plasticity and Promotes Tauopathy-Related Memory Loss.

Neuron 2016 04 31;90(2):245-60. Epub 2016 Mar 31.

Gladstone Institute of Neurological Disease, San Francisco, CA 91458, USA; Department of Neurology, University of California, San Francisco, San Francisco, CA 91458, USA; Neuroscience Graduate Program, University of California, San Francisco, San Francisco, CA 91458, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.neuron.2016.03.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4859346PMC
April 2016

Protein acetylation dynamics in response to carbon overflow in Escherichia coli.

Mol Microbiol 2015 Dec 10;98(5):847-63. Epub 2015 Sep 10.

Department of Microbiology and Immunology, Stritch School of Medicine, Health Sciences Division, Loyola University Chicago, Maywood, IL, 60153, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/mmi.13161DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4715485PMC
December 2015

MS1 Peptide Ion Intensity Chromatograms in MS2 (SWATH) Data Independent Acquisitions. Improving Post Acquisition Analysis of Proteomic Experiments.

Mol Cell Proteomics 2015 Sep 17;14(9):2405-19. Epub 2015 May 17.

From the ‡Buck Institute for Research on Aging, 8001 Redwood Blvd, Novato, California 94945; **Department of Pharmaceutical Chemistry, University of California, San Francisco, California 94143

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/mcp.O115.048181DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4563724PMC
September 2015

SIRT1 deacetylates RORγt and enhances Th17 cell generation.

J Exp Med 2015 May 27;212(5):607-17. Epub 2015 Apr 27.

Gladstone Institute of Virology and Immunology, Gladstone Institute of Neurological Disease, School of Medecine, Department of Neurology, Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, CA 94158 Gladstone Institute of Virology and Immunology, Gladstone Institute of Neurological Disease, School of Medecine, Department of Neurology, Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, CA 94158

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1084/jem.20132378DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4419343PMC
May 2015

Wavelet-based peak detection and a new charge inference procedure for MS/MS implemented in ProteoWizard's msConvert.

J Proteome Res 2015 Feb 2;14(2):1299-307. Epub 2014 Dec 2.

Department of Biomedical Informatics, Vanderbilt University Medical Center , Nashville, Tennessee 37232-8340, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/pr500886yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4324452PMC
February 2015

The E. coli sirtuin CobB shows no preference for enzymatic and nonenzymatic lysine acetylation substrate sites.

Microbiologyopen 2015 Feb 22;4(1):66-83. Epub 2014 Nov 22.

Department of Microbiology and Immunology, Loyola University Chicago, Health Sciences Division, Stritch School of Medicine, Maywood, Illinois, 60153; Department of Microbiology, Faculty of Pharmacy, Alexandria University, Alexandria, 21521, Egypt.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/mbo3.223DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4335977PMC
February 2015

Structural, kinetic and proteomic characterization of acetyl phosphate-dependent bacterial protein acetylation.

PLoS One 2014 22;9(4):e94816. Epub 2014 Apr 22.

Department of Microbiology and Immunology, Stritch School of Medicine, Health Sciences Division, Loyola University Chicago, Maywood, Illinois, United States of America.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0094816PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995681PMC
January 2015

A framework for installable external tools in Skyline.

Bioinformatics 2014 Sep 9;30(17):2521-3. Epub 2014 May 9.

Department of Genome Sciences, University of Washington, Seattle, WA 98195, Department of Statistics, Purdue University, West Lafayette, IN 47907, Broad Institute of MIT and Harvard, Cambridge, MA 02142 and Buck Institute for Research on Aging, Novato, CA 94945, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/bioinformatics/btu148DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4147880PMC
September 2014

Site-specific acylation changes in the lipid A of Escherichia coli lpxL mutants grown at high temperatures.

Innate Immun 2014 Apr 28;20(3):269-82. Epub 2013 Jun 28.

1The Buck Institute for Research on Aging, Novato, CA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/1753425913490534DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3983921PMC
April 2014

Elucidation of N-glycosites within human plasma glycoproteins for cancer biomarker discovery.

Methods Mol Biol 2013 ;951:307-22

Department of Obstetrics, Gynecology and Reproductive Sciences, University of California, San Francisco, CA, USA.

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/978-1-62703-146-2_21
Publisher Site
http://dx.doi.org/10.1007/978-1-62703-146-2_21DOI Listing
June 2013

QuaMeter: multivendor performance metrics for LC-MS/MS proteomics instrumentation.

Anal Chem 2012 Jul 27;84(14):5845-50. Epub 2012 Jun 27.

Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, Tennessee 37232-8575, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/ac300629pDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3730131PMC
July 2012

Ubiquitin-specific peptidase 9, X-linked (USP9X) modulates activity of mammalian target of rapamycin (mTOR).

J Biol Chem 2012 Jun 27;287(25):21164-75. Epub 2012 Apr 27.

Buck Institute for Research on Aging, Novato, California 94945, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M111.328021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3375539PMC
June 2012

ScanRanker: Quality assessment of tandem mass spectra via sequence tagging.

J Proteome Res 2011 Jul 26;10(7):2896-904. Epub 2011 Apr 26.

Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, Tennessee 37232-8340, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/pr200118rDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3128668PMC
July 2011

The Mycobacterium bovis bacille Calmette-Guerin phagosome proteome.

Mol Cell Proteomics 2010 Jan 7;9(1):32-53. Epub 2009 Oct 7.

Division of Infectious Diseases, Department of Medicine, Center for Health Sciences, University of California-Los Angeles School of Medicine, Los Angeles, California 90095-1688, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/mcp.M900396-MCP200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2808266PMC
January 2010

Partial acetylation of lysine residues improves intraprotein cross-linking.

Anal Chem 2008 Feb 18;80(4):951-60. Epub 2008 Jan 18.

Department of Pharmaceutics and Medicinal Chemistry, University of the Pacific, Stockton, CA 95211, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/ac701636wDOI Listing
February 2008

Identification of LpxL, a late acyltransferase of Francisella tularensis.

Infect Immun 2007 Nov 27;75(11):5518-31. Epub 2007 Aug 27.

Department of Microbiology and Inflammation Program, University of Iowa, Iowa City, Iowa, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/IAI.01288-06DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2168286PMC
November 2007

Novel pathways associated with quinone-induced stress in breast cancer cells.

Drug Metab Rev 2006 ;38(4):601-13

Cancer and Developmental Therapeutics Program, Buck Institute for Age Research, Novato, CA 94945, USA.

View Article

Download full-text PDF

Source
http://www.tandfonline.com/doi/full/10.1080/0360253060095939
Publisher Site
http://dx.doi.org/10.1080/03602530600959391 DOI Listing
January 2007

Novel modification of lipid A of Francisella tularensis.

Infect Immun 2004 Sep;72(9):5340-8

Department of Pharmaceutical Chemistry, University of California, San Francisco, California, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/IAI.72.9.5340-5348.2004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC517411PMC
September 2004

Molecular components of a cell death pathway activated by endoplasmic reticulum stress.

J Biol Chem 2004 Jan 15;279(1):177-87. Epub 2003 Oct 15.

The Buck Institute for Age Research, Novato, California 94945, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M304490200DOI Listing
January 2004

Isotopically labeled crosslinking reagents: resolution of mass degeneracy in the identification of crosslinked peptides.

Bioorg Med Chem Lett 2003 Nov;13(22):4023-6

Department of Pharmaceutical Chemistry, University of California at San Francisco, San Francisco, CA 94143, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bmcl.2003.08.053DOI Listing
November 2003

Phosphospecific proteolysis for mapping sites of protein phosphorylation.

Nat Biotechnol 2003 Sep 17;21(9):1047-54. Epub 2003 Aug 17.

Program in Chemistry and Chemical Biology, University of California, San Francisco, California 94143-0446, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nbt863DOI Listing
September 2003

MS2Assign, automated assignment and nomenclature of tandem mass spectra of chemically crosslinked peptides.

J Am Soc Mass Spectrom 2003 Aug;14(8):834-50

Buck Institute for Age Research, Novato, California 94143-0446, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/S1044-0305(03)00327-1DOI Listing
August 2003

Metabolic incorporation of unnatural sialic acids into Haemophilus ducreyi lipooligosaccharides.

Proc Natl Acad Sci U S A 2003 Mar 3;100(6):3089-94. Epub 2003 Mar 3.

Department of Chemistry and Molecular, Howard Hughes Medical Institute, University of California, Los Angeles, CA 90065, USA.

View Article

Download full-text PDF

Source
http://www.pnas.org/cgi/doi/10.1073/pnas.0437851100
Publisher Site
http://dx.doi.org/10.1073/pnas.0437851100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC152251PMC
March 2003

Characterization of lipooligosaccharides from Haemophilus ducreyi containing polylactosamine repeats.

J Am Soc Mass Spectrom 2002 Jun;13(6):724-34

Buck Institute for Age Research, Novato, California 94945, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/S1044-0305(02)00375-6DOI Listing
June 2002