Birgit Sawitzki

Birgit Sawitzki

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Birgit Sawitzki

Birgit Sawitzki

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Single-cell analysis based dissection of clonality in myelofibrosis.

Nat Commun 2020 Jan 7;11(1):73. Epub 2020 Jan 7.

Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Department of Hematology, Oncology, and Tumor Immunology, Berlin, Germany.

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http://dx.doi.org/10.1038/s41467-019-13892-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6946829PMC
January 2020

Guidelines for the use of flow cytometry and cell sorting in immunological studies (second edition).

Authors:
Andrea Cossarizza Hyun-Dong Chang Andreas Radbruch Andreas Acs Dieter Adam Sabine Adam-Klages William W Agace Nima Aghaeepour Mübeccel Akdis Matthieu Allez Larissa Nogueira Almeida Giorgia Alvisi Graham Anderson Immanuel Andrä Francesco Annunziato Achille Anselmo Petra Bacher Cosima T Baldari Sudipto Bari Vincenzo Barnaba Joana Barros-Martins Luca Battistini Wolfgang Bauer Sabine Baumgart Nicole Baumgarth Dirk Baumjohann Bianka Baying Mary Bebawy Burkhard Becher Wolfgang Beisker Vladimir Benes Rudi Beyaert Alfonso Blanco Dominic A Boardman Christian Bogdan Jessica G Borger Giovanna Borsellino Philip E Boulais Jolene A Bradford Dirk Brenner Ryan R Brinkman Anna E S Brooks Dirk H Busch Martin Büscher Timothy P Bushnell Federica Calzetti Garth Cameron Ilenia Cammarata Xuetao Cao Susanna L Cardell Stefano Casola Marco A Cassatella Andrea Cavani Antonio Celada Lucienne Chatenoud Pratip K Chattopadhyay Sue Chow Eleni Christakou Luka Čičin-Šain Mario Clerici Federico S Colombo Laura Cook Anne Cooke Andrea M Cooper Alexandra J Corbett Antonio Cosma Lorenzo Cosmi Pierre G Coulie Ana Cumano Ljiljana Cvetkovic Van Duc Dang Chantip Dang-Heine Martin S Davey Derek Davies Sara De Biasi Genny Del Zotto Gelo Victoriano Dela Cruz Michael Delacher Silvia Della Bella Paolo Dellabona Günnur Deniz Mark Dessing James P Di Santo Andreas Diefenbach Francesco Dieli Andreas Dolf Thomas Dörner Regine J Dress Diana Dudziak Michael Dustin Charles-Antoine Dutertre Friederike Ebner Sidonia B G Eckle Matthias Edinger Pascale Eede Götz R A Ehrhardt Marcus Eich Pablo Engel Britta Engelhardt Anna Erdei Charlotte Esser Bart Everts Maximilien Evrard Christine S Falk Todd A Fehniger Mar Felipo-Benavent Helen Ferry Markus Feuerer Andrew Filby Kata Filkor Simon Fillatreau Marie Follo Irmgard Förster John Foster Gemma A Foulds Britta Frehse Paul S Frenette Stefan Frischbutter Wolfgang Fritzsche David W Galbraith Anastasia Gangaev Natalio Garbi Brice Gaudilliere Ricardo T Gazzinelli Jens Geginat Wilhelm Gerner Nicholas A Gherardin Kamran Ghoreschi Lara Gibellini Florent Ginhoux Keisuke Goda Dale I Godfrey Christoph Goettlinger Jose M González-Navajas Carl S Goodyear Andrea Gori Jane L Grogan Daryl Grummitt Andreas Grützkau Claudia Haftmann Jonas Hahn Hamida Hammad Günter Hämmerling Leo Hansmann Goran Hansson Christopher M Harpur Susanne Hartmann Andrea Hauser Anja E Hauser David L Haviland David Hedley Daniela C Hernández Guadalupe Herrera Martin Herrmann Christoph Hess Thomas Höfer Petra Hoffmann Kristin Hogquist Tristan Holland Thomas Höllt Rikard Holmdahl Pleun Hombrink Jessica P Houston Bimba F Hoyer Bo Huang Fang-Ping Huang Johanna E Huber Jochen Huehn Michael Hundemer Christopher A Hunter William Y K Hwang Anna Iannone Florian Ingelfinger Sabine M Ivison Hans-Martin Jäck Peter K Jani Beatriz Jávega Stipan Jonjic Toralf Kaiser Tomas Kalina Thomas Kamradt Stefan H E Kaufmann Baerbel Keller Steven L C Ketelaars Ahad Khalilnezhad Srijit Khan Jan Kisielow Paul Klenerman Jasmin Knopf Hui-Fern Koay Katja Kobow Jay K Kolls Wan Ting Kong Manfred Kopf Thomas Korn Katharina Kriegsmann Hendy Kristyanto Thomas Kroneis Andreas Krueger Jenny Kühne Christian Kukat Désirée Kunkel Heike Kunze-Schumacher Tomohiro Kurosaki Christian Kurts Pia Kvistborg Immanuel Kwok Jonathan Landry Olivier Lantz Paola Lanuti Francesca LaRosa Agnès Lehuen Salomé LeibundGut-Landmann Michael D Leipold Leslie Y T Leung Megan K Levings Andreia C Lino Francesco Liotta Virginia Litwin Yanling Liu Hans-Gustaf Ljunggren Michael Lohoff Giovanna Lombardi Lilly Lopez Miguel López-Botet Amy E Lovett-Racke Erik Lubberts Herve Luche Burkhard Ludewig Enrico Lugli Sebastian Lunemann Holden T Maecker Laura Maggi Orla Maguire Florian Mair Kerstin H Mair Alberto Mantovani Rudolf A Manz Aaron J Marshall Alicia Martínez-Romero Glòria Martrus Ivana Marventano Wlodzimierz Maslinski Giuseppe Matarese Anna Vittoria Mattioli Christian Maueröder Alessio Mazzoni James McCluskey Mairi McGrath Helen M McGuire Iain B McInnes Henrik E Mei Fritz Melchers Susanne Melzer Dirk Mielenz Stephen D Miller Kingston H G Mills Hans Minderman Jenny Mjösberg Jonni Moore Barry Moran Lorenzo Moretta Tim R Mosmann Susann Müller Gabriele Multhoff Luis Enrique Muñoz Christian Münz Toshinori Nakayama Milena Nasi Katrin Neumann Lai Guan Ng Antonia Niedobitek Sussan Nourshargh Gabriel Núñez José-Enrique O'Connor Aaron Ochel Anna Oja Diana Ordonez Alberto Orfao Eva Orlowski-Oliver Wenjun Ouyang Annette Oxenius Raghavendra Palankar Isabel Panse Kovit Pattanapanyasat Malte Paulsen Dinko Pavlinic Livius Penter Pärt Peterson Christian Peth Jordi Petriz Federica Piancone Winfried F Pickl Silvia Piconese Marcello Pinti A Graham Pockley Malgorzata Justyna Podolska Zhiyong Poon Katharina Pracht Immo Prinz Carlo E M Pucillo Sally A Quataert Linda Quatrini Kylie M Quinn Helena Radbruch Tim R D J Radstake Susann Rahmig Hans-Peter Rahn Bartek Rajwa Gevitha Ravichandran Yotam Raz Jonathan A Rebhahn Diether Recktenwald Dorothea Reimer Caetano Reis E Sousa Ester B M Remmerswaal Lisa Richter Laura G Rico Andy Riddell Aja M Rieger J Paul Robinson Chiara Romagnani Anna Rubartelli Jürgen Ruland Armin Saalmüller Yvan Saeys Takashi Saito Shimon Sakaguchi Francisco Sala-de-Oyanguren Yvonne Samstag Sharon Sanderson Inga Sandrock Angela Santoni Ramon Bellmàs Sanz Marina Saresella Catherine Sautes-Fridman Birgit Sawitzki Linda Schadt Alexander Scheffold Hans U Scherer Matthias Schiemann Frank A Schildberg Esther Schimisky Andreas Schlitzer Josephine Schlosser Stephan Schmid Steffen Schmitt Kilian Schober Daniel Schraivogel Wolfgang Schuh Thomas Schüler Reiner Schulte Axel Ronald Schulz Sebastian R Schulz Cristiano Scottá Daniel Scott-Algara David P Sester T Vincent Shankey Bruno Silva-Santos Anna Katharina Simon Katarzyna M Sitnik Silvano Sozzani Daniel E Speiser Josef Spidlen Anders Stahlberg Alan M Stall Natalie Stanley Regina Stark Christina Stehle Tobit Steinmetz Hannes Stockinger Yousuke Takahama Kiyoshi Takeda Leonard Tan Attila Tárnok Gisa Tiegs Gergely Toldi Julia Tornack Elisabetta Traggiai Mohamed Trebak Timothy I M Tree Joe Trotter John Trowsdale Maria Tsoumakidou Henning Ulrich Sophia Urbanczyk Willem van de Veen Maries van den Broek Edwin van der Pol Sofie Van Gassen Gert Van Isterdael René A W van Lier Marc Veldhoen Salvador Vento-Asturias Paulo Vieira David Voehringer Hans-Dieter Volk Anouk von Borstel Konrad von Volkmann Ari Waisman Rachael V Walker Paul K Wallace Sa A Wang Xin M Wang Michael D Ward Kirsten A Ward-Hartstonge Klaus Warnatz Gary Warnes Sarah Warth Claudia Waskow James V Watson Carsten Watzl Leonie Wegener Thomas Weisenburger Annika Wiedemann Jürgen Wienands Anneke Wilharm Robert John Wilkinson Gerald Willimsky James B Wing Rieke Winkelmann Thomas H Winkler Oliver F Wirz Alicia Wong Peter Wurst Jennie H M Yang Juhao Yang Maria Yazdanbakhsh Liping Yu Alice Yue Hanlin Zhang Yi Zhao Susanne Maria Ziegler Christina Zielinski Jakob Zimmermann Arturo Zychlinsky

Eur J Immunol 2019 Oct;49(10):1457-1973

Max Planck Institute for Infection Biology, Berlin, Germany.

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http://dx.doi.org/10.1002/eji.201970107DOI Listing
October 2019

MAIT Cells as Drivers of Renal Fibrosis and CKD.

Authors:
Birgit Sawitzki

J Am Soc Nephrol 2019 Jul 11;30(7):1145-1146. Epub 2019 Jun 11.

Institute of Medical Immunology, Charité University Medicine, Berlin, Germany

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http://dx.doi.org/10.1681/ASN.2019050468DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6622413PMC
July 2019

Long-Term Signs of T Cell and Myeloid Cell Activation After Intestinal Transplantation With Cellular Rejections Contributing to Further Increase of CD16 Cell Subsets.

Front Immunol 2019 7;10:866. Epub 2019 May 7.

Institute for Medical Immunology, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin and Berlin Institute of Health, Berlin, Germany.

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https://www.frontiersin.org/article/10.3389/fimmu.2019.00866
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http://dx.doi.org/10.3389/fimmu.2019.00866DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6514047PMC
May 2019

BKV, CMV, and EBV Interactions and their Effect on Graft Function One Year Post-Renal Transplantation: Results from a Large Multi-Centre Study.

EBioMedicine 2018 Aug 30;34:113-121. Epub 2018 Jul 30.

Berlin-Brandenburg Center for Regenerative Therapies (BCRT), Charité-Universitätsmedizin Berlin, Augustenburger Platz 1, 13353 Berlin, Germany; Medical Department 1, Universitätsklinikum der Ruhr-Universität Bochum, Ruhr-Universität Bochum, Hölkeskampring 40, 44625 Herne, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2018.07.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6116415PMC
August 2018

CD96 expression determines the inflammatory potential of IL-9-producing Th9 cells.

Proc Natl Acad Sci U S A 2018 03 12;115(13):E2940-E2949. Epub 2018 Mar 12.

Charité-Universitaetsmedizin Berlin, corporate member of Freie Universitaet Berlin, Humboldt-Universitaet zu Berlin, and Berlin Institute of Health, Institute for Medical Immunology, 13353 Berlin, Germany;

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http://dx.doi.org/10.1073/pnas.1708329115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5879650PMC
March 2018

Short-term cytokine stimulation reveals regulatory T cells with down-regulated Foxp3 expression in human peripheral blood.

Eur J Immunol 2018 02 2;48(2):366-379. Epub 2017 Nov 2.

Institute for Virology and Immunobiology, University of Würzburg, Würzburg, Germany.

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http://dx.doi.org/10.1002/eji.201747244DOI Listing
February 2018

Author Correction: Mild hypothermia provides Treg stability.

Sci Rep 2017 12 15;7(1):17940. Epub 2017 Dec 15.

Department of Clinical Immunology and Transplantology, Medical University of Gdańsk, ul. Dębinki 7, 80-210, Gdańsk, Poland.

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http://dx.doi.org/10.1038/s41598-017-17186-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732292PMC
December 2017

Guidelines for the use of flow cytometry and cell sorting in immunological studies.

Authors:
Andrea Cossarizza Hyun-Dong Chang Andreas Radbruch Mübeccel Akdis Immanuel Andrä Francesco Annunziato Petra Bacher Vincenzo Barnaba Luca Battistini Wolfgang M Bauer Sabine Baumgart Burkhard Becher Wolfgang Beisker Claudia Berek Alfonso Blanco Giovanna Borsellino Philip E Boulais Ryan R Brinkman Martin Büscher Dirk H Busch Timothy P Bushnell Xuetao Cao Andrea Cavani Pratip K Chattopadhyay Qingyu Cheng Sue Chow Mario Clerici Anne Cooke Antonio Cosma Lorenzo Cosmi Ana Cumano Van Duc Dang Derek Davies Sara De Biasi Genny Del Zotto Silvia Della Bella Paolo Dellabona Günnur Deniz Mark Dessing Andreas Diefenbach James Di Santo Francesco Dieli Andreas Dolf Vera S Donnenberg Thomas Dörner Götz R A Ehrhardt Elmar Endl Pablo Engel Britta Engelhardt Charlotte Esser Bart Everts Anita Dreher Christine S Falk Todd A Fehniger Andrew Filby Simon Fillatreau Marie Follo Irmgard Förster John Foster Gemma A Foulds Paul S Frenette David Galbraith Natalio Garbi Maria Dolores García-Godoy Jens Geginat Kamran Ghoreschi Lara Gibellini Christoph Goettlinger Carl S Goodyear Andrea Gori Jane Grogan Mor Gross Andreas Grützkau Daryl Grummitt Jonas Hahn Quirin Hammer Anja E Hauser David L Haviland David Hedley Guadalupe Herrera Martin Herrmann Falk Hiepe Tristan Holland Pleun Hombrink Jessica P Houston Bimba F Hoyer Bo Huang Christopher A Hunter Anna Iannone Hans-Martin Jäck Beatriz Jávega Stipan Jonjic Kerstin Juelke Steffen Jung Toralf Kaiser Tomas Kalina Baerbel Keller Srijit Khan Deborah Kienhöfer Thomas Kroneis Désirée Kunkel Christian Kurts Pia Kvistborg Joanne Lannigan Olivier Lantz Anis Larbi Salome LeibundGut-Landmann Michael D Leipold Megan K Levings Virginia Litwin Yanling Liu Michael Lohoff Giovanna Lombardi Lilly Lopez Amy Lovett-Racke Erik Lubberts Burkhard Ludewig Enrico Lugli Holden T Maecker Glòria Martrus Giuseppe Matarese Christian Maueröder Mairi McGrath Iain McInnes Henrik E Mei Fritz Melchers Susanne Melzer Dirk Mielenz Kingston Mills David Mirrer Jenny Mjösberg Jonni Moore Barry Moran Alessandro Moretta Lorenzo Moretta Tim R Mosmann Susann Müller Werner Müller Christian Münz Gabriele Multhoff Luis Enrique Munoz Kenneth M Murphy Toshinori Nakayama Milena Nasi Christine Neudörfl John Nolan Sussan Nourshargh José-Enrique O'Connor Wenjun Ouyang Annette Oxenius Raghav Palankar Isabel Panse Pärt Peterson Christian Peth Jordi Petriz Daisy Philips Winfried Pickl Silvia Piconese Marcello Pinti A Graham Pockley Malgorzata Justyna Podolska Carlo Pucillo Sally A Quataert Timothy R D J Radstake Bartek Rajwa Jonathan A Rebhahn Diether Recktenwald Ester B M Remmerswaal Katy Rezvani Laura G Rico J Paul Robinson Chiara Romagnani Anna Rubartelli Beate Ruckert Jürgen Ruland Shimon Sakaguchi Francisco Sala-de-Oyanguren Yvonne Samstag Sharon Sanderson Birgit Sawitzki Alexander Scheffold Matthias Schiemann Frank Schildberg Esther Schimisky Stephan A Schmid Steffen Schmitt Kilian Schober Thomas Schüler Axel Ronald Schulz Ton Schumacher Cristiano Scotta T Vincent Shankey Anat Shemer Anna-Katharina Simon Josef Spidlen Alan M Stall Regina Stark Christina Stehle Merle Stein Tobit Steinmetz Hannes Stockinger Yousuke Takahama Attila Tarnok ZhiGang Tian Gergely Toldi Julia Tornack Elisabetta Traggiai Joe Trotter Henning Ulrich Marlous van der Braber René A W van Lier Marc Veldhoen Salvador Vento-Asturias Paulo Vieira David Voehringer Hans-Dieter Volk Konrad von Volkmann Ari Waisman Rachael Walker Michael D Ward Klaus Warnatz Sarah Warth James V Watson Carsten Watzl Leonie Wegener Annika Wiedemann Jürgen Wienands Gerald Willimsky James Wing Peter Wurst Liping Yu Alice Yue Qianjun Zhang Yi Zhao Susanne Ziegler Jakob Zimmermann

Eur J Immunol 2017 10;47(10):1584-1797

Maurice Müller Laboratories (DKF), Universitätsklinik für Viszerale Chirurgie und Medizin Inselspital, University of Bern, Murtenstrasse, Bern.

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http://doi.wiley.com/10.1002/eji.201646632
Publisher Site
http://dx.doi.org/10.1002/eji.201646632DOI Listing
October 2017

IRF1 and BATF-transcription factors that set the epigenetic landscape for Tr1 cell differentiation?

Cell Mol Immunol 2017 09 10;14(9):727-729. Epub 2017 Jul 10.

Charité-Universitaetsmedizin Berlin, Corporate Member of Freie Universitaet Berlin, Humboldt-Universitaet zu Berlin, and Berlin Institute of Health, Institute of Medical Immunology, Augustenburger Platz 1, 13353 Berlin, Germany.

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http://dx.doi.org/10.1038/cmi.2017.50DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5596247PMC
September 2017

Mild hypothermia provides Treg stability.

Sci Rep 2017 09 20;7(1):11915. Epub 2017 Sep 20.

Department of Clinical Immunology and Transplantology, Medical University of Gdańsk, ul. Dębinki 7, 80-210, Gdańsk, Poland.

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http://dx.doi.org/10.1038/s41598-017-10151-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5607276PMC
September 2017

No prolongation of skin allograft survival by immunoproteasome inhibition in mice.

Mol Immunol 2017 08 2;88:32-37. Epub 2017 Jun 2.

Division of Immunology, Department of Biology, Universitaetsstrasse 10, University of Konstanz, 78457 Konstanz, Germany; Biotechnology Institute Thurgau at the University of Konstanz (BITg), Unterseestrasse 47, 8280 Kreuzlingen, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.molimm.2017.05.022DOI Listing
August 2017

Isolation, characterization and cold storage of cells isolated from diseased explanted livers.

Int J Artif Organs 2017 Jun 23;40(6):294-306. Epub 2017 May 23.

 Department of Surgery, Experimental Surgery and Regenerative Medicine, Campus Charité Mitte-Campus Virchow-Klinikum, Charité Universitaetsmedizin Berlin, Berlin - Germany.

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http://dx.doi.org/10.5301/ijao.5000594DOI Listing
June 2017

Intragraft and Systemic Immune Parameters Discriminating Between Rejection and Long-Term Graft Function in a Preclinical Model of Intestinal Transplantation.

Transplantation 2017 05;101(5):1036-1045

1 Department of General, Visceral, and Transplantation Surgery, Charité Universitaetsmedizin Berlin, Campus Virchow Klinikum, Berlin, Germany. 2 Institute of Medical Immunology, Charité Universitaetsmedizin Berlin, Campus Virchow Klinikum, Berlin, Germany. 3 Institute of Pathology/Research Center ImmunoSciences (RCIS), Charité Universitaetsmedizin Berlin, Campus Virchow Klinikum, Berlin, Germany.

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http://dx.doi.org/10.1097/TP.0000000000001469DOI Listing
May 2017

CD45RA Distinguishes CD4+CD25+CD127-/low TSDR Demethylated Regulatory T Cell Subpopulations With Differential Stability and Susceptibility to Tacrolimus-Mediated Inhibition of Suppression.

Transplantation 2017 Feb;101(2):302-309

1 Nuffield Department of Surgical Sciences, Oxford University, John Radcliffe Hospital, Oxford, United Kingdom. 2 Charité-Universitätsmedizin Berlin, Campus Virchow, Institut f. Medizinische Immunologie, Berlin, Germany. 3 Oxford Transplant Centre, Oxford University Hospitals NHS Trust, Oxford, United Kingdom.

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http://dx.doi.org/10.1097/TP.0000000000001278DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5265687PMC
February 2017

Wild immunology assessed by multidimensional mass cytometry.

Cytometry A 2017 01 12;91(1):85-95. Epub 2016 Jul 12.

Regenerative Immunology and Aging, BCRT, Charité Universitätsmedizin Berlin, Berlin, Germany.

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http://dx.doi.org/10.1002/cyto.a.22906DOI Listing
January 2017

Non-HLA Antibodies May Accelerate Immune Responses After Intestinal and Multivisceral Transplantation.

Transplantation 2017 Jan;101(1):141-149

1 Department of General, Visceral and Transplantation Surgery, Charité-Universitätsmedizin Berlin, Campus Virchow Klinikum, Berlin, Germany. 2 Institute for Transfusion Medicine and HLA Typing Laboratory, Charité-Universitätsmedizin Berlin, Campus Virchow Klinikum, Berlin, Germany. 3 Institute for Medical Immunology, Charité-Universitätsmedizin Berlin, Campus Virchow Klinikum, Berlin, Germany. 4 Department for Nephrology and Intensive Care Medicine, Charité-Universitätsmedizin Berlin, Campus Virchow Klinikum, Berlin, Germany.

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http://dx.doi.org/10.1097/TP.0000000000001439DOI Listing
January 2017

Immune monitoring in renal transplantation: The search for biomarkers.

Eur J Immunol 2016 12;46(12):2695-2704

Inserm, , Center for Research in Transplantation and Immunology (CRTI) U1064, Nantes, France.

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http://dx.doi.org/10.1002/eji.201545963DOI Listing
December 2016

Regulatory T Cell Specificity Directs Tolerance versus Allergy against Aeroantigens in Humans.

Cell 2016 11 20;167(4):1067-1078.e16. Epub 2016 Oct 20.

Department of Cellular Immunology, Clinic for Rheumatology and Clinical Immunology, Charité - University Medicine Berlin, 10117 Berlin, Germany; German Rheumatism Research Centre (DRFZ) Berlin, Leibniz Association, 10117 Berlin, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2016.09.050DOI Listing
November 2016

Clinical Use of Tolerogenic Dendritic Cells-Harmonization Approach in European Collaborative Effort.

Mediators Inflamm 2015 24;2015:471719. Epub 2015 Dec 24.

Immunology Division, Germans Trias i Pujol University Hospital, Department of Cellular Biology, Physiology, and Immunology, Universitat Autònoma Barcelona, Campus Can Ruti, 08916 Barcelona, Spain.

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http://dx.doi.org/10.1155/2015/471719DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4706930PMC
September 2016

Effector T cell subclasses associate with tumor burden in neurofibromatosis type 1 patients.

Cancer Immunol Immunother 2016 09 23;65(9):1113-21. Epub 2016 Jul 23.

Berlin-Brandenburg Center for Regenerative Therapies, Charité - Universitätsmedizin Berlin, Augustenburger Platz 1, 13353, Berlin, Germany.

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http://dx.doi.org/10.1007/s00262-016-1871-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4995232PMC
September 2016

Standardized Multi-Color Flow Cytometry and Computational Biomarker Discovery.

Methods Mol Biol 2016 ;1371:225-38

Institute of Medical Immunology, Charité University Medicine, Berlin, 10117, Germany.

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http://dx.doi.org/10.1007/978-1-4939-3139-2_15DOI Listing
August 2016

Low-dose interleukin-2 selectively corrects regulatory T cell defects in patients with systemic lupus erythematosus.

Ann Rheum Dis 2016 07 31;75(7):1407-15. Epub 2015 Aug 31.

Department of Rheumatology and Clinical Immunology, Charité-University Medicine Berlin, Berlin, Germany German Rheumatism Research Center (DRFZ), a Leibniz Institute, Berlin, Germany.

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http://ard.bmj.com/content/early/2015/08/30/annrheumdis-2015
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http://ard.bmj.com/lookup/doi/10.1136/annrheumdis-2015-20777
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http://dx.doi.org/10.1136/annrheumdis-2015-207776DOI Listing
July 2016

Early Enrichment and Restitution of the Peripheral Blood Treg Pool Is Associated With Rejection-Free Stable Immunosuppression After Liver Transplantation.

Transplantation 2016 07;100(7):e39-40

1 Department of Surgery, University Hospital Regensburg, Regensburg, Germany. 2 Department of Internal Medicine III, University Hospital Regensburg, Regensburg, Germany. 3 Department of General and Visceral Surgery, University Hospital Frankfurt, Frankfurt am Main, Germany. 4 Institute for Medical Immunology, Berlin Charité University Hospital, Berlin, Germany.

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http://dx.doi.org/10.1097/TP.0000000000001190DOI Listing
July 2016

Allogeneic Liver Transplantation and Subsequent Syngeneic Hepatocyte Transplantation in a Rat Model: Proof of Concept for in vivo Tissue Engineering.

Cells Tissues Organs 2015 -2016;201(6):399-411. Epub 2016 May 20.

General, Visceral and Transplantation Surgery, Experimental Surgery and Regenerative Medicine, Campus Virchow-Klinikum, Berlin, Germany.

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http://dx.doi.org/10.1159/000445792DOI Listing
May 2016

Differences in CD44 Surface Expression Levels and Function Discriminates IL-17 and IFN-γ Producing Helper T Cells.

PLoS One 2015 14;10(7):e0132479. Epub 2015 Jul 14.

Institute of Medical Immunology, Charité University Medicine, Berlin, Germany; Berlin Brandenburg Center for Regenerative Therapies, Charité University Medicine, Berlin, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0132479PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4501817PMC
April 2016

Central Role of CD45RA- Foxp3hi Memory Regulatory T Cells in Clinical Kidney Transplantation Tolerance.

J Am Soc Nephrol 2015 Aug 2;26(8):1795-805. Epub 2015 Jan 2.

French Institute of Health and Medical Research Unit 1064, Research Institute on Urology, Nephrology, and Transplantation, and Biotherapy Clinical Investigation Center, Hôtel Dieu University Hospital, Nantes, France; and

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http://dx.doi.org/10.1681/ASN.2014050480DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4520169PMC
August 2015

The use of novel diagnostics to individualize immunosuppression following transplantation.

Transpl Int 2015 Aug 4;28(8):911-20. Epub 2015 Feb 4.

Institute of Medical Immunology, CCM, Charité University Berlin, Berlin, Germany.

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http://dx.doi.org/10.1111/tri.12527DOI Listing
August 2015

Effect of induction therapy on the expression of molecular markers associated with rejection and tolerance.

BMC Nephrol 2015 Aug 19;16:146. Epub 2015 Aug 19.

Transplant Laboratory, Centre for Experimental Medicine, Institute for Clinical and Experimental Medicine, Prague, Czech Republic.

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http://dx.doi.org/10.1186/s12882-015-0141-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4545708PMC
August 2015

TCAIM decreases T cell priming capacity of dendritic cells by inhibiting TLR-induced Ca2+ influx and IL-2 production.

J Immunol 2015 Apr 6;194(7):3136-46. Epub 2015 Mar 6.

Institute of Medical Immunology, Charite University Medicine, Berlin 13353, Germany; Berlin Brandenburg Center for Regenerative Therapies, Charite University Medicine, Berlin 13353, Germany;

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http://dx.doi.org/10.4049/jimmunol.1400713DOI Listing
April 2015

Cellular energy metabolism in T-lymphocytes.

Int Rev Immunol 2015 Jan 26;34(1):34-49. Epub 2014 Sep 26.

1Department of Rheumatology and Clinical Immunology, Charité University Hospital, Berlin, Germany.

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http://dx.doi.org/10.3109/08830185.2014.956358DOI Listing
January 2015

Short-term TNF-alpha inhibition reduces short-term and long-term inflammatory changes post-ischemia/reperfusion in rat intestinal transplantation.

Transplantation 2014 Apr;97(7):732-9

1 Department of General, Visceral, and Transplantation Surgery, Charité, Campus Virchow Klinikum, Universitaetsmedizin Berlin, Berlin, Germany. 2 Department of Visceral, Transplantation, Thoracic, and Vascular Surgery, Universitaetsklinik Leipzig, Leipzig, Germany. 3 Institute of Pathology, Charité, Campus Benjamin Franklin, Universitaetsmedizin Berlin, Berlin, Germany. 4 Institute of Medical Immunology, Charité, Campus Mitte, Universitaetsmedizin Berlin, Berlin, Germany. 5 Address correspondence to: Andreas Pascher, M.D., Ph.D., M.B.A., F.E.B.S., Department of General, Visceral, and Transplantation Surgery, Charité Universitaetsmedizin Berlin, Campus Virchow Klinikum, Augustenburgerplatz 1, 13353 Berlin, Germany.

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April 2014

Clinical relevance of the de novo production of anti-HLA antibodies following intestinal and multivisceral transplantation.

Transpl Int 2014 Mar 16;27(3):280-9. Epub 2014 Jan 16.

Department of General, Visceral and Transplantation Surgery, Campus Virchow Klinikum, Charité-Universitätsmedizin Berlin, Berlin, Germany.

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http://dx.doi.org/10.1111/tri.12250DOI Listing
March 2014

Prospective assessment of antidonor cellular alloreactivity is a tool for guidance of immunosuppression in kidney transplantation.

Kidney Int 2013 Dec 19;84(6):1226-36. Epub 2013 Jun 19.

1] Renal Transplant Unit, Nephrology Department, Bellvitge University Hospital, Barcelona, Spain [2] Experimental Nephrology Department, IDIBELL, Barcelona University, Barcelona, Spain.

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http://dx.doi.org/10.1038/ki.2013.236DOI Listing
December 2013

Microglial activation milieu controls regulatory T cell responses.

J Immunol 2013 Dec 21;191(11):5594-602. Epub 2013 Oct 21.

Institute for Cell Biology and Neurobiology, Charité-University Medicine Berlin, 10117 Berlin, Germany;

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December 2013

Foxp3+ Helios+ regulatory T cells are expanded in active systemic lupus erythematosus.

Ann Rheum Dis 2013 Sep 21;72(9):1549-58. Epub 2012 Dec 21.

Medical Department, Division of Rheumatology and Clinical Immunology, Charité-University Medicine, Berlin, Germany.

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September 2013

Allogeneic partially HLA-matched dendritic cells pulsed with autologous tumor cell lysate as a vaccine in metastatic renal cell cancer: a clinical phase I/II study.

Hum Vaccin Immunother 2013 Jun 4;9(6):1217-27. Epub 2013 Mar 4.

Department of Hematology; Oncology, and Tumor Immunology; Charité University Medicine Berlin; Campus Virchow- Klinikum; Berlin, Germany; Department of Hematology; Oncology, and Tumor Immunology; Charité University Medicine Berlin; Campus Benjamin Franklin; Berlin, Germany.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3901809PMC
June 2013

Serum biomarkers for neurofibromatosis type 1 and early detection of malignant peripheral nerve-sheath tumors.

BMC Med 2013 Apr 23;11:109. Epub 2013 Apr 23.

Berlin-Brandenburg Center for Regenerative Therapies, Charité - Universitätsmedizin Berlin, Augustenburger Platz 1, Berlin, 13353, Germany.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3648455PMC
April 2013

Peripheral biomarkers for individualizing immunosuppression in transplantation--regulatory T cells.

Clin Chim Acta 2012 Sep 18;413(17-18):1406-13. Epub 2012 Feb 18.

Institute of Medical Immunology, Charite Universitätsmedizin, Berlin, Germany.

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September 2012

Low-dose cyclosporine mediates donor hyporesponsiveness in a fully mismatched rat kidney transplant model.

Transpl Immunol 2012 Jun 4;26(4):176-85. Epub 2012 Mar 4.

Department of Visceral, Transplantation and Thoracic Surgery, Medizinische Universitaet Innsbruck, Austria; Division of Transplant Surgery, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

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June 2012

Tregs: application for solid-organ transplantation.

Curr Opin Organ Transplant 2012 Feb;17(1):34-41

Institute of Medical Immunology, Charité University Medicine, Augustenburger Platz 1, Berlin, Germany.

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February 2012

Synovial and peripheral blood CD4+FoxP3+ T cells in spondyloarthritis.

J Rheumatol 2011 Nov 15;38(11):2445-51. Epub 2011 Sep 15.

Department of Gastroenterology, Infectiology and Rheumatology, Charité-Universitätsmedizin Berlin, Campus Benjamin Franklin, Berlin, Germany.

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http://dx.doi.org/10.3899/jrheum.110377DOI Listing
November 2011

Functional human regulatory T cells fail to control autoimmune inflammation due to PKB/c-akt hyperactivation in effector cells.

Blood 2011 Sep 9;118(13):3538-48. Epub 2011 Aug 9.

Center for Molecular and Cellular Intervention, Department of Immunology, Wilhelmina Children’s Hospital, University Medical Center Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.1182/blood-2010-12-328187DOI Listing
September 2011

Monitoring tolerance and rejection in organ transplant recipients.

Biomarkers 2011 Jul;16 Suppl 1:S42-50

Institute of Medical Immunology, Charite University Medicine, Berlin, Germany.

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http://dx.doi.org/10.3109/1354750X.2011.578754DOI Listing
July 2011

State of the art on the research for biomarkers allowing individual, tailor-made minimization of immunosuppression.

Curr Opin Organ Transplant 2010 Dec;15(6):691-6

aInstitute of Medical Immunology, CCM, Germany bBerlin-Brandenburg Center for Regenerative Therapies (BCRT), CVK, Germany cDepartment of Nephrology and Intensive Care, CVK, Germany dDepartment of Surgery, CVK, Charité University Berlin, Berlin, Germany.

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December 2010

Influence of combined treatment of low dose rapamycin and cyclosporin A on corneal allograft survival.

Graefes Arch Clin Exp Ophthalmol 2010 Oct 24;248(10):1447-56. Epub 2010 Jun 24.

Department of Ophthalmology, Charité University Medicine, 10117, Berlin, Germany.

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October 2010

CD30 discriminates heat shock protein 60-induced FOXP3+ CD4+ T cells with a regulatory phenotype.

J Immunol 2010 Aug 14;185(4):2071-9. Epub 2010 Jul 14.

Center for Molecular and Cellular Immunology, University Medical Center Utrecht, The Netherlands.

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August 2010

Generation of HCMV-specific T-cell lines from seropositive solid-organ-transplant recipients for adoptive T-cell therapy.

J Immunother 2009 Nov-Dec;32(9):932-40

Department of Nephrology and Internal Intensive Care, Charité-Universitätsmedizin Berlin, Campus Virchow Klinikum, Berlin, Germany.

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January 2010

Alpha-1,2-mannosidase and hence N-glycosylation are required for regulatory T cell migration and allograft tolerance in mice.

PLoS One 2010 Jan 26;5(1):e8894. Epub 2010 Jan 26.

Transplant Research Immunology Group, Nuffield Department of Surgery, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2811199PMC
January 2010

Pretransplant immune risk assessment.

Curr Opin Organ Transplant 2009 Dec;14(6):650-5

Institute of Medical Immunology, CCM, Germany.

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December 2009

Can we use biomarkers and functional assays to implement personalized therapies in transplantation?

Transplantation 2009 Jun;87(11):1595-601

Institute of Medical Immunology, Campus Charité Mitte, Charite University Medicine, Berlin, Germany.

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http://dx.doi.org/10.1097/TP.0b013e3181a6b2cfDOI Listing
June 2009

Anti-CD4-mediated selection of Treg in vitro - in vitro suppression does not predict in vivo capacity to prevent graft rejection.

Eur J Immunol 2008 Jun;38(6):1677-88

Transplantation Research Immunology Group, Nuffield Department of Surgery, University of Oxford, John Radcliffe Hospital, Oxford, UK.

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http://dx.doi.org/10.1002/eji.200737562DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2988420PMC
June 2008

Autoimmunity and transplantation: a meeting at the crossroads in Berlin.

Nat Immunol 2008 May;9(5):447-9

Institute of Medical Immunology, Charité-University Medicine Berlin, 10117 Berlin, Germany. birgit.sawitzki@charite

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http://dx.doi.org/10.1038/ni0508-447DOI Listing
May 2008

Exhaustive differentiation of alloreactive CD8+ T cells: critical for determination of graft acceptance or rejection.

Transplantation 2008 May;85(9):1339-47

Nuffield Department of Surgery, John Radcliffe Hospital, University of Oxford, Oxford, England.

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http://dx.doi.org/10.1097/TP.0b013e31816dd64aDOI Listing
May 2008

Ex vivo gene transfer of viral interleukin-10 to BB rat islets: no protection after transplantation to diabetic BB rats.

J Cell Mol Med 2007 Jul-Aug;11(4):868-80

Institute of Physiology, Medical School, Ernst-Moritz-Arndt-University of Greifswald, Greifswalderstrasse 11c, D-17495 Karlsburg, Germany.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3823263PMC
November 2007

Interferon gamma: friend or foe?

Transplantation 2007 Jul;84(1 Suppl):S4-5

Transplantation Research Immunology Group, Nuffield Department of Surgery, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom.

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July 2007

Interferon gamma: a crucial role in the function of induced regulatory T cells in vivo.

Trends Immunol 2006 Apr 9;27(4):183-7. Epub 2006 Mar 9.

Transplantation Research Immunology Group, Nuffield Department of Surgery, John Radcliffe Hospital, University of Oxford, Oxford, UK OX3 9DU.

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http://dx.doi.org/10.1016/j.it.2006.02.008DOI Listing
April 2006

Protection from abortion by heme oxygenase-1 up-regulation is associated with increased levels of Bag-1 and neuropilin-1 at the fetal-maternal interface.

J Immunol 2005 Oct;175(8):4875-85

Reproductive Immunology Group, Institute of Medical Immunology, Biomedizinisches Forschungszentrum (BMFZ), Charité Medical University of Berlin, Germany.

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October 2005

IFN-gamma production by alloantigen-reactive regulatory T cells is important for their regulatory function in vivo.

J Exp Med 2005 Jun;201(12):1925-35

Nuffield Department of Surgery, John Radcliffe Hospital, University of Oxford, Oxford OX3 9DU, England, UK.

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http://dx.doi.org/10.1084/jem.20050419DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2212028PMC
June 2005

IFN-gamma regulation in anti-CD4 antibody-induced T cell unresponsiveness.

J Am Soc Nephrol 2004 Mar;15(3):695-703

Department of Medical Immunology, Charité-Campus Mitte, Humboldt-University Berlin, Berlin, Germany.

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http://dx.doi.org/10.1097/01.asn.0000115523.50962.c0DOI Listing
March 2004

Expression of p16INK4a and other cell cycle regulator and senescence associated genes in aging human kidney.

Kidney Int 2004 Feb;65(2):510-20

Division of Nephrology and Immunology, Department of Medicine, University of Alberta, Edmonton, Alberta, Canada.

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February 2004

Alloantigen-induced CD25+CD4+ regulatory T cells can develop in vivo from CD25-CD4+ precursors in a thymus-independent process.

J Immunol 2004 Jan;172(2):923-8

Nuffield Department of Surgery, University of Oxford, John Radcliffe Hospital, Headington, Oxford OX3 9DU, United Kingdom.

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http://dx.doi.org/10.4049/jimmunol.172.2.923DOI Listing
January 2004

Impact of hepatic rearterialization on reperfusion injury and outcome after mouse liver transplantation.

Transplantation 2003 Jul;76(2):327-32

Nuffield Department of Surgery, John Radcliffe Hospital, University of Oxford, Oxford, England.

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http://dx.doi.org/10.1097/01.TP.0000071521.36828.F7DOI Listing
July 2003

Erythropoietin is a paracrine mediator of ischemic tolerance in the brain: evidence from an in vitro model.

J Neurosci 2002 Dec;22(23):10291-301

Department of Experimental Neurology, Charité Hospital, Humboldt University, D-10098 Berlin, Germany.

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December 2002

Fas ligand breaks tolerance to self-antigens and induces tumor immunity mediated by antibodies.

Cancer Cell 2002 Oct;2(4):315-22

MRC Human Immunology Unit and Nuffield Department of Medicine, Institute of Molecular Medicine, OX3 9DS, Oxford, United Kingdom.

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http://dx.doi.org/10.1016/s1535-6108(02)00151-4DOI Listing
October 2002

Upregulation of Bag-1 by ex vivo gene transfer protects rat livers from ischemia/reperfusion injury.

Hum Gene Ther 2002 Aug;13(12):1495-504

Nuffield Department of Surgery, John Radcliffe Hospital, Oxford University, UK.

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http://dx.doi.org/10.1089/10430340260185120DOI Listing
August 2002