Birgit Rathkolb

Birgit Rathkolb

UNVERIFIED PROFILE

Are you Birgit Rathkolb?   Register this Author

Register author
Birgit Rathkolb

Birgit Rathkolb

Publications by authors named "Birgit Rathkolb"

Are you Birgit Rathkolb?   Register this Author

100Publications

4599Reads

47Profile Views

In-depth phenotyping reveals common and novel disease symptoms in a hemizygous knock-in mouse model (Mut-ko/ki) of mut-type methylmalonic aciduria.

Biochim Biophys Acta Mol Basis Dis 2020 Mar 23;1866(3):165622. Epub 2019 Nov 23.

Division of Metabolism and Children's Research Center, University Children's Hospital Zurich, Zurich, Switzerland; radiz - Rare Disease Initiative Zurich, Clinical Research Priority Program for Rare Diseases, University of Zurich, Zurich, Switzerland; Zurich Center for Integrative Human Physiology, University of Zurich, Zurich, Switzerland. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbadis.2019.165622DOI Listing
March 2020

Multi-omics insights into functional alterations of the liver in insulin-deficient diabetes mellitus.

Mol Metab 2019 08 4;26:30-44. Epub 2019 Jun 4.

Laboratory for Functional Genome Analysis (LAFUGA), Gene Center, LMU Munich, 81377 Munich, Germany; German Center for Diabetes Research (DZD), 85764 Neuherberg, Germany; Chair for Molecular Animal Breeding and Biotechnology, Gene Center and Department of Veterinary Sciences, LMU Munich, 81377 Munich, Germany; Center for Innovative Medical Models (CiMM), LMU Munich, 85764 Oberschleißheim, Germany. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.molmet.2019.05.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6667734PMC
August 2019

Dilution correction for dynamically influenced urinary analyte data.

Anal Chim Acta 2018 Nov 28;1032:18-31. Epub 2018 Jul 28.

Research Unit of Molecular Epidemiology, Helmholtz Zentrum München, Germany; Institute of Epidemiology, Helmholtz Zentrum München, Germany; German Center for Diabetes Research (DZD), München, Germany.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S00032670183093
Publisher Site
http://dx.doi.org/10.1016/j.aca.2018.07.068DOI Listing
November 2018

Understanding gene functions and disease mechanisms: Phenotyping pipelines in the German Mouse Clinic.

Behav Brain Res 2018 10 29;352:187-196. Epub 2017 Sep 29.

German Mouse Clinic, Institute of Experimental Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health, Ingolstädter-Landstr. 1, 85764 Neuherberg, Germany; German Center for Diabetes Research (DZD), Ingolstädter-Landstr. 1, 85764 Neuherberg, Germany; Chair of Experimental Genetics, School of Life Science Weihenstephan, Technische Universität München, Alte Akademie 8, 85354 Freising, Germany. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbr.2017.09.048DOI Listing
October 2018

Metabolic syndrome and extensive adipose tissue inflammation in morbidly obese Göttingen minipigs.

Mol Metab 2018 10 28;16:180-190. Epub 2018 Jun 28.

Chair for Molecular Animal Breeding and Biotechnology, Gene Center and Department of Veterinary Sciences, LMU Munich, Feodor-Lynen-Str. 25, 81377, Munich, Germany; Center for Innovative Medical Models (CiMM), Department of Veterinary Sciences, LMU Munich, Hackerstr. 27, 85764, Oberschleißheim, Germany; German Center for Diabetes Research (DZD), Ingolstädter Landstr. 1, 85764, Neuherberg, Germany; Laboratory for Functional Genome Analysis (LAFUGA), Gene Center, LMU Munich, Feodor-Lynen-Str. 25, 81377, Munich, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.molmet.2018.06.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6157610PMC
October 2018

Growth hormone receptor-deficient pigs resemble the pathophysiology of human Laron syndrome and reveal altered activation of signaling cascades in the liver.

Mol Metab 2018 05 15;11:113-128. Epub 2018 Mar 15.

Chair for Molecular Animal Breeding and Biotechnology, Gene Center and Department of Veterinary Sciences, LMU Munich, Feodor-Lynen-Str. 25, 81377 Munich, Germany; Center for Innovative Medical Models (CiMM), Department of Veterinary Sciences, LMU Munich, Hackerstr. 27, 85764 Oberschleißheim, Germany; Meiji University International Institute for Bio-Resource Research, 1-1-1 Higashimita, Tama, Kawasaki, 214-8571, Japan; German Center for Diabetes Research (DZD), Helmholtz Zentrum München, Ingolstädter Landstr. 1, 85764 Neuherberg, Germany; Laboratory for Functional Genome Analysis (LAFUGA), Gene Center, LMU Munich, Feodor-Lynen-Str. 25, 81377 Munich, Germany. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.molmet.2018.03.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6001387PMC
May 2018

Identification of genetic elements in metabolism by high-throughput mouse phenotyping.

Nat Commun 2018 01 18;9(1):288. Epub 2018 Jan 18.

German Mouse Clinic, Institute of Experimental Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health, Ingolstädter Landstr. 1, 85764, Neuherberg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41467-017-01995-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5773596PMC
January 2018

The Munich MIDY Pig Biobank - A unique resource for studying organ crosstalk in diabetes.

Mol Metab 2017 08 13;6(8):931-940. Epub 2017 Jun 13.

Chair for Molecular Animal Breeding and Biotechnology, Gene Center and Department of Veterinary Sciences, and Center for Innovative Medical Models (CiMM), LMU Munich, Feodor-Lynen-Str. 25, D-81377 Munich, Germany; German Center for Diabetes Research (DZD), Ingolstädter Landstr. 1, D-85764 Neuherberg, Germany; Laboratory for Functional Genome Analysis (LAFUGA), Gene Center, LMU Munich, Feodor-Lynen-Str. 25, D-81377 Munich, Germany. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S22128778173031
Publisher Site
http://dx.doi.org/10.1016/j.molmet.2017.06.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5518720PMC
August 2017

A novel biological function of soluble biglycan: Induction of erythropoietin production and polycythemia.

Glycoconj J 2017 06 6;34(3):393-404. Epub 2016 Sep 6.

Pharmazentrum Frankfurt, Institut für Allgemeine Pharmakologie und Toxikologie, Klinikum der Goethe-Universität Frankfurt am Main, Frankfurt am Main, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10719-016-9722-yDOI Listing
June 2017

Modification of the fatty acid composition of an obesogenic diet improves the maternal and placental metabolic environment in obese pregnant mice.

Biochim Biophys Acta Mol Basis Dis 2017 06 21;1863(6):1605-1614. Epub 2017 Feb 21.

Research Center, Dr. von Hauner Children's Hospital, Ludwig-Maximilians-Universität München, Lindwurmstrasse 4, 80337 Munich, Germany; Experimental Pediatrics and Metabolism, Department of General Pediatrics, Neonatology and Pediatric Cardiology, University Children's Hospital, Heinrich Heine University Düsseldorf, Moorenstrasse 5, 40225 Düsseldorf, Germany. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbadis.2017.02.021DOI Listing
June 2017

Bezafibrate ameliorates diabetes via reduced steatosis and improved hepatic insulin sensitivity in diabetic TallyHo mice.

Mol Metab 2017 03 6;6(3):256-266. Epub 2017 Jan 6.

Institute of Experimental Genetics, Helmholtz Zentrum München, Ingolstädter Landstraße 1, 85764 Neuherberg, Germany; German Center for Diabetes Research (DZD e.V.), Ingolstädter Landstraße 1, 85764 Neuherberg, Germany; Center of Life and Food Sciences Weihenstephan, Technische Universität München, Alte Akademie 8, 85354 Freising, Germany. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.molmet.2016.12.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323884PMC
March 2017

Clinical Chemistry Reference Intervals for C57BL/6J, C57BL/6N, and C3HeB/FeJ Mice (Mus musculus).

J Am Assoc Lab Anim Sci 2016 ;55(4):375-86

German Mouse Clinic, Institute of Experimental Genetics, Helmholtz Zentrum Muenchen, Germany; German Research Center for Environmental Health, Neuherberg, Germany; German Center for Diabetes Research, Neuherberg, Germany; Experimental Genetics, Center of Life and Food Sciences, Weihenstephan, Technische Universitaet Muenchen, Freising-Weihenstephan, Germany.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4943607PMC
February 2017

Bezafibrate Improves Insulin Sensitivity and Metabolic Flexibility in STZ-Induced Diabetic Mice.

Diabetes 2016 09 9;65(9):2540-52. Epub 2016 Jun 9.

Institute of Experimental Genetics, Helmholtz Zentrum München, Neuherberg, Germany German Center for Diabetes Research (DZD e.V.), Neuherberg, Germany German Mouse Clinic, Helmholtz Zentrum München, Neuherberg, Germany Center of Life and Food Sciences Weihenstephan, Technische Universität München, Freising, Germany

View Article

Download full-text PDF

Source
http://diabetes.diabetesjournals.org/content/diabetes/early/
Web Search
http://dx.doi.org/10.2337/db15-1670DOI Listing
September 2016

Iron deficiency anemia in cyclic GMP kinase knockout mice.

Haematologica 2016 Feb;101(2):e48-51

Institut für Pharmakologie und Toxikologie, Technische Universität München

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3324/haematol.2015.137026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4938340PMC
February 2016

MFAP4 Promotes Vascular Smooth Muscle Migration, Proliferation and Accelerates Neointima Formation.

Arterioscler Thromb Vasc Biol 2016 Jan 12;36(1):122-33. Epub 2015 Nov 12.

From the Institute of Molecular Medicine, University of Southern Denmark, Odense, Denmark (A.S., B.P., L.E.H., K.K., G.B.K., H.W.-J., J.B.M., K.K.-M., L.K.D., P.B.L.H., J.S., U.H, G.L.S.); Department of Molecular Biology and Genetics, Aarhus University, Aarhus, Denmark (E.-M.F.); Department of Pathology, Odense University Hospital, Odense, Denmark (O.N.); Institute of Functional and Applied Anatomy, Hannover Medical School, Hannover, Germany (C.W., J.H., M.O.); Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH), Member of the German Center for Lung Research (DZL), Hannover, Germany (C.W., J.H., M.O.); REBIRTH Cluster of Excellence, Hannover, Germany (C.W., J.H., M.O.); German Mouse Clinic, Institute of Experimental Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health, Munich, Germany (B.R., A.S., V.G.-D., H.F., M.H.d.A.); Institute of Molecular Animal Breeding and Biotechnology, Gene Center, Ludwig-Maximilians-University München, Munich, Germany (B.R, E.W.); Division of Cardiology, Department of Medicine III, University of Heidelberg, Heidelberg, Germany (A.S., R.B.); Chair of Experimental Genetics, Center of Life and Food Sciences Weihenstephan, Technische Universität München, Freising-Weihenstephan, Munich, Germany (M.H.d.A.); Cardiovascular Research Unit, Viborg Hospital, Viborg, Denmark (J.S.L.); and Department of Cardiothoracic and Vascular Surgery, Center of Individualized Medicine in Arterial Diseases (CIMA), Odense University Hospital, Odense, Denmark (J.S.L.).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1161/ATVBAHA.115.306672DOI Listing
January 2016

Analysis of mammalian gene function through broad-based phenotypic screens across a consortium of mouse clinics.

Authors:
Martin Hrabě de Angelis George Nicholson Mohammed Selloum Jacqui White Hugh Morgan Ramiro Ramirez-Solis Tania Sorg Sara Wells Helmut Fuchs Martin Fray David J Adams Niels C Adams Thure Adler Antonio Aguilar-Pimentel Dalila Ali-Hadji Gregory Amann Philippe André Sarah Atkins Aurelie Auburtin Abdel Ayadi Julien Becker Lore Becker Elodie Bedu Raffi Bekeredjian Marie-Christine Birling Andrew Blake Joanna Bottomley Mike Bowl Véronique Brault Dirk H Busch James N Bussell Julia Calzada-Wack Heather Cater Marie-France Champy Philippe Charles Claire Chevalier Francesco Chiani Gemma F Codner Roy Combe Roger Cox Emilie Dalloneau André Dierich Armida Di Fenza Brendan Doe Arnaud Duchon Oliver Eickelberg Chris T Esapa Lahcen El Fertak Tanja Feigel Irina Emelyanova Jeanne Estabel Jack Favor Ann Flenniken Alessia Gambadoro Lilian Garrett Hilary Gates Anna-Karin Gerdin George Gkoutos Simon Greenaway Lisa Glasl Patrice Goetz Isabelle Goncalves Da Cruz Alexander Götz Jochen Graw Alain Guimond Wolfgang Hans Geoff Hicks Sabine M Hölter Heinz Höfler John M Hancock Robert Hoehndorf Tertius Hough Richard Houghton Anja Hurt Boris Ivandic Hughes Jacobs Sylvie Jacquot Nora Jones Natasha A Karp Hugo A Katus Sharon Kitchen Tanja Klein-Rodewald Martin Klingenspor Thomas Klopstock Valerie Lalanne Sophie Leblanc Christoph Lengger Elise le Marchand Tonia Ludwig Aline Lux Colin McKerlie Holger Maier Jean-Louis Mandel Susan Marschall Manuel Mark David G Melvin Hamid Meziane Kateryna Micklich Christophe Mittelhauser Laurent Monassier David Moulaert Stéphanie Muller Beatrix Naton Frauke Neff Patrick M Nolan Lauryl Mj Nutter Markus Ollert Guillaume Pavlovic Natalia S Pellegata Emilie Peter Benoit Petit-Demoulière Amanda Pickard Christine Podrini Paul Potter Laurent Pouilly Oliver Puk David Richardson Stephane Rousseau Leticia Quintanilla-Fend Mohamed M Quwailid Ildiko Racz Birgit Rathkolb Fabrice Riet Janet Rossant Michel Roux Jan Rozman Ed Ryder Jennifer Salisbury Luis Santos Karl-Heinz Schäble Evelyn Schiller Anja Schrewe Holger Schulz Ralf Steinkamp Michelle Simon Michelle Stewart Claudia Stöger Tobias Stöger Minxuan Sun David Sunter Lydia Teboul Isabelle Tilly Glauco P Tocchini-Valentini Monica Tost Irina Treise Laurent Vasseur Emilie Velot Daniela Vogt-Weisenhorn Christelle Wagner Alison Walling Bruno Weber Olivia Wendling Henrik Westerberg Monja Willershäuser Eckhard Wolf Anne Wolter Joe Wood Wolfgang Wurst Ali Önder Yildirim Ramona Zeh Andreas Zimmer Annemarie Zimprich Chris Holmes Karen P Steel Yann Herault Valérie Gailus-Durner Ann-Marie Mallon Steve Dm Brown

Nat Genet 2015 Sep 27;47(9):969-978. Epub 2015 Jul 27.

MRC Harwell, Medical Research Council, Harwell, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ng.3360DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564951PMC
September 2015

Screen for alterations of iron related parameters in N-ethyl-N-nitrosourea-treated mice identified mutant lines with increased plasma ferritin levels.

Biometals 2015 Apr 31;28(2):293-306. Epub 2015 Jan 31.

Chair for Molecular Animal Breeding and Biotechnology, Department of Veterinary Sciences, and Laboratory for Functional Genome Analysis (LAFUGA), Gene Center, LMU Munich, Feodor-Lynen-Str. 25, 81377, Munich, Germany,

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10534-015-9824-1DOI Listing
April 2015

Glucose tolerance tests for systematic screening of glucose homeostasis in mice.

Curr Protoc Mouse Biol 2015 Mar 2;5(1):65-84. Epub 2015 Mar 2.

Institute of Experimental Genetics, German Mouse Clinic, Helmholtz-Zentrum München, German Center for Environmental Health, Neuherberg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/9780470942390.mo140111DOI Listing
March 2015

Metformin supports the antidiabetic effect of a sodium glucose cotransporter 2 inhibitor by suppressing endogenous glucose production in diabetic mice.

Diabetes 2015 Jan 28;64(1):284-90. Epub 2014 Jul 28.

Institute of Experimental Genetics, Helmholtz Zentrum München, Neuherberg/Munich, Germany German Mouse Clinic, Institute of Experimental Genetics, Helmholtz Zentrum München, Neuherberg/Munich, Germany German Center for Diabetes Research, Neuherberg/Munich, Germany Technische Universität München-Weihenstephan, Helmholtz Zentrum München, Neuherberg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2337/db14-0393DOI Listing
January 2015

No amelioration of uromodulin maturation and trafficking defect by sodium 4-phenylbutyrate in vivo: studies in mouse models of uromodulin-associated kidney disease.

J Biol Chem 2014 Apr 24;289(15):10715-26. Epub 2014 Feb 24.

From the Chair for Molecular Animal Breeding and Biotechnology, Gene Center, Ludwig-Maximilians-Universität München, 81377 Munich, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M113.537035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4036188PMC
April 2014

Phenotypic comparison of common mouse strains developing high-fat diet-induced hepatosteatosis.

Mol Metab 2013 3;2(4):435-46. Epub 2013 Aug 3.

Institute of Experimental Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health, Ingolstädter Landstrasse 1, 85764 Neuherberg/Munich, Germany ; German Center for Diabetes Research (DZD), Ingolstädter Landstraße 1, 85764 Neuherberg/Munich, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.molmet.2013.07.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3855089PMC
December 2013

Clinical Chemistry and Other Laboratory Tests on Mouse Plasma or Serum.

Curr Protoc Mouse Biol 2013 Jun 1;3(2):69-100. Epub 2013 Jun 1.

Institute of Experimental Genetics, German Mouse Clinic, Helmholtz-Zentrum München, German Research Center for Environmental Health, GmbH, Neuherberg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/9780470942390.mo130043DOI Listing
June 2013

Blood Collection from Mice and Hematological Analyses on Mouse Blood.

Curr Protoc Mouse Biol 2013 Jun 1;3(2):101-19. Epub 2013 Jun 1.

Institute of Experimental Genetics, German Mouse Clinic, Helmholtz-Zentrum München, German Research Center for Environmental Health, GmbH, Neuherberg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/9780470942390.mo130054DOI Listing
June 2013

Gender-, strain-, and inheritance-dependent variation in aldosterone secretion in mice.

J Endocrinol 2012 Dec 26;215(3):375-81. Epub 2012 Sep 26.

Endocrine Research Unit, Medizinische Klinik und Poliklinik IV, Klinikum der Universität München, LMU, Ziemssenstrasse 1, D-80336 Munich, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1530/JOE-12-0429DOI Listing
December 2012

Innovations in phenotyping of mouse models in the German Mouse Clinic.

Mamm Genome 2012 Oct 29;23(9-10):611-22. Epub 2012 Aug 29.

German Mouse Clinic, Institute of Experimental Genetics, Helmholtz Zentrum München, German Research Center for Environmental Health (GmbH), Ingolstädter Landstrasse 1, 85764 Neuherberg/Munich, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00335-012-9415-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3463795PMC
October 2012

Clinical chemistry of human FcRn transgenic mice.

Mamm Genome 2012 Apr 23;23(3-4):259-69. Epub 2011 Dec 23.

Roche Diagnostics GmbH, Pharma Research and Early Development, Nonnenwald 2, 82377, Penzberg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00335-011-9379-6DOI Listing
April 2012

Generation of N-ethyl-N-nitrosourea-induced mouse mutants with deviations in hematological parameters.

Mamm Genome 2011 Oct 8;22(9-10):495-505. Epub 2011 May 8.

Department of Veterinary Sciences, Chair for Molecular Animal Breeding and Biotechnology, and Laboratory for Functional Genome Analysis (LAFUGA), Gene Center, LMU Munich, Moorversuchsgut, Hackerstr. 27, 85764, Oberschleiβheim, Munich, Germany.

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s00335-011-9328-4
Publisher Site
http://dx.doi.org/10.1007/s00335-011-9328-4DOI Listing
October 2011

Utilization of a mutagenesis screen to generate mouse models of hyperaldosteronism.

Endocrinology 2011 Jan 10;152(1):326-31. Epub 2010 Nov 10.

Department of Medicine, Endocrine Research, University Hospital Innenstadt, Ziemssenstr. 1, D-80336 Munich, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1210/en.2010-1081DOI Listing
January 2011

Mutation of the Na(+)-K(+)-2Cl(-) cotransporter NKCC2 in mice is associated with severe polyuria and a urea-selective concentrating defect without hyperreninemia.

Am J Physiol Renal Physiol 2010 Jun 10;298(6):F1405-15. Epub 2010 Mar 10.

Molecular Animal Breeding and Biotechnology, and Laboratory for Functional Genome Analysis (LAFUGA), Gene Center, LMU Munich, Munich, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1152/ajprenal.00522.2009DOI Listing
June 2010

Novel missense mutation of uromodulin in mice causes renal dysfunction with alterations in urea handling, energy, and bone metabolism.

Am J Physiol Renal Physiol 2009 Nov 19;297(5):F1391-8. Epub 2009 Aug 19.

Chair for Molecular Animal Breeding and Biotechnology and Laboratory for Functional Genome Analysis, Gene Center, Ludwig-Maximilians-Universität Munich, Munich, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1152/ajprenal.00261.2009DOI Listing
November 2009

N-ethyl-N-nitrosourea mutagenesis produced a small number of mice with altered plasma electrolyte levels.

J Biomed Sci 2009 Jun 8;16:53. Epub 2009 Jun 8.

Chair for Molecular Animal Breeding and Biotechnology, Department of Veterinary Sciences, and Laboratory for Functional Genome Analysis (LAFUGA), Gene Center, LMU Munich, Munich, Germany.

View Article

Download full-text PDF

Source
http://www.jbiomedsci.com/content/16/1/53
Publisher Site
http://dx.doi.org/10.1186/1423-0127-16-53DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2697975PMC
June 2009

Generation of N-ethyl-N-nitrosourea-induced mouse mutants with deviations in plasma enzyme activities as novel organ-specific disease models.

Exp Physiol 2009 Apr 16;94(4):412-21. Epub 2009 Jan 16.

Department of Veterinary Sciences and Laboratory for Functional Genome Analysis (LAFUGA), Gene Center, Ludwig-Maximilians-University Munich, Munich, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1113/expphysiol.2008.045864DOI Listing
April 2009

Diabetes models by screen for hyperglycemia in phenotype-driven ENU mouse mutagenesis projects.

Am J Physiol Endocrinol Metab 2008 Feb 4;294(2):E232-40. Epub 2007 Dec 4.

Institute of Molecular Animal Breeding and Biotechnology, Hackerstrasse 27, Oberschleissheim, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1152/ajpendo.00592.2007DOI Listing
February 2008