Bingcheng Wang

Bingcheng Wang

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Bingcheng Wang

Bingcheng Wang

Publications by authors named "Bingcheng Wang"

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A quantitative LC-MS/MS method for determination of a small molecule agonist of EphA2 in mouse plasma and brain tissue.

Biomed Chromatogr 2019 Apr 16;33(4):e4461. Epub 2019 Jan 16.

Rammelkamp Center for Research and Department of Medicine, MetroHealth System, Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.

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http://dx.doi.org/10.1002/bmc.4461DOI Listing
April 2019

Caught in the "Akt": Cross-talk between EphA2 and EGFR through the Akt-PIKfyve axis maintains cellular sensitivity to EGF.

Sci Signal 2018 Jul 31;11(541). Epub 2018 Jul 31.

Rammelkamp Center for Research and Department of Medicine, MetroHealth Campus; and Departments of Pharmacology, Oncology, Physiology and Biophysics, Case Comprehensive Cancer Center, Case Western Reserve University School of Medicine, 2500 MetroHealth Drive, Cleveland, OH 44109, USA.

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http://dx.doi.org/10.1126/scisignal.aau1207DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311088PMC
July 2018

Design and synthesis of small molecule agonists of EphA2 receptor.

Eur J Med Chem 2018 Jan 10;143:1261-1276. Epub 2017 Oct 10.

Rammelkamp Center for Research and Department of Medicine, MetroHealth Campus, Case Western Reserve University School of Medicine, Cleveland, OH, USA; Case Comprehensive Cancer Center, Case Western Reserve University School of Medicine, Cleveland, OH, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ejmech.2017.10.026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5752149PMC
January 2018

Towards precision medicine-based therapies for glioblastoma: interrogating human disease genomics and mouse phenotypes.

BMC Genomics 2016 08 22;17 Suppl 7:516. Epub 2016 Aug 22.

Department of Epidemiology and Biostatistics, Case Western Reserve University, Cleveland, Ohio, USA.

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http://dx.doi.org/10.1186/s12864-016-2908-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5001238PMC
August 2016

Eph/ephrin signaling in epidermal differentiation and disease.

Semin Cell Dev Biol 2012 Feb 21;23(1):92-101. Epub 2011 Oct 21.

Department of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA.

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http://dx.doi.org/10.1016/j.semcdb.2011.10.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3378995PMC
February 2012

EphA receptor signaling--complexity and emerging themes.

Semin Cell Dev Biol 2012 Feb 21;23(1):16-25. Epub 2011 Oct 21.

Rammelkamp Center for Research, MetroHealth Campus, Case Western Reserve University School of Medicine, 2500 MetroHealth Drive, Cleveland, OH 44109, USA.

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http://dx.doi.org/10.1016/j.semcdb.2011.10.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3374974PMC
February 2012

Cancer cells exploit the Eph-ephrin system to promote invasion and metastasis: tales of unwitting partners.

Authors:
Bingcheng Wang

Sci Signal 2011 May 31;4(175):pe28. Epub 2011 May 31.

Rammelkamp Center for Research and Department of Medicine, MetroHealth Campus, Case Western Reserve University School of Medicine, 2500 MetroHealth Drive, Cleveland, OH 44109, USA.

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http://dx.doi.org/10.1126/scisignal.2002153DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431919PMC
May 2011

A novel extracellular Hsp90 mediated co-receptor function for LRP1 regulates EphA2 dependent glioblastoma cell invasion.

PLoS One 2011 Mar 8;6(3):e17649. Epub 2011 Mar 8.

Department of Cell and Molecular Pharmacology, Medical University of South Carolina, Charleston, South Carolina, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0017649PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3050925PMC
March 2011

DHT selectively reverses Smad3-mediated/TGF-beta-induced responses through transcriptional down-regulation of Smad3 in prostate epithelial cells.

Mol Endocrinol 2010 Oct 25;24(10):2019-29. Epub 2010 Aug 25.

Case Comprehensive Cancer Center Research Laboratories, Division of Pediatric Hematology/Oncology, Rainbow Babies and Children's Hospital, Case Western Reserve University, Cleveland, Ohio 44106, USA.

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http://dx.doi.org/10.1210/me.2010-0165DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2954637PMC
October 2010

Eph/ephrin signaling in epithelial development and homeostasis.

Int J Biochem Cell Biol 2009 Apr 9;41(4):762-70. Epub 2008 Aug 9.

Rammelkamp Center for Research, MetroHealth Campus, Case Western Reserve University School of Medicine, 2500 MetroHealth Drive, Cleveland, OH 44109, United States.

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http://dx.doi.org/10.1016/j.biocel.2008.07.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3108796PMC
April 2009

Differences in regulation of type I collagen synthesis in primary and passaged hepatic stellate cell cultures: the role of alpha5beta1-integrin.

Am J Physiol Gastrointest Liver Physiol 2007 Jul 17;293(1):G154-64. Epub 2007 May 17.

Department of Gastroenterology and Hepatology, Cleveland Clinic and Cleveland Clinic Lerner College of Medicine, 9500 Euclid Avenue, Cleveland, OH 44195, USA.

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http://www.physiology.org/doi/10.1152/ajpgi.00432.2006
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http://dx.doi.org/10.1152/ajpgi.00432.2006DOI Listing
July 2007

Beta8 integrin binds Rho GDP dissociation inhibitor-1 and activates Rac1 to inhibit mesangial cell myofibroblast differentiation.

J Biol Chem 2006 Jul 11;281(28):19688-99. Epub 2006 May 11.

Department of Medicine, Case Western Reserve University School of Medicine, Rammelkamp Center for Education and Research, MetroHealth Medical Center, Cleveland, Ohio 44109, USA.

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http://dx.doi.org/10.1074/jbc.M601110200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2711893PMC
July 2006

Disruption of EphA2 receptor tyrosine kinase leads to increased susceptibility to carcinogenesis in mouse skin.

Cancer Res 2006 Jul;66(14):7050-8

Rammelkamp Center for Research and Department of Pharmacology and Comprehensive Cancer Center.

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http://dx.doi.org/10.1158/0008-5472.CAN-06-0004DOI Listing
July 2006

Inhibition of integrin-mediated cell adhesion but not directional cell migration requires catalytic activity of EphB3 receptor tyrosine kinase. Role of Rho family small GTPases.

J Biol Chem 2005 Jan 9;280(2):923-32. Epub 2004 Nov 9.

Rammelkamp Center for Research, MetroHealth Campus, and Department of Pharmacology and Ireland Cancer Center, Case Western Reserve University School of Medicine, Cleveland, Ohio 44109, USA.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M411383200
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http://dx.doi.org/10.1074/jbc.M411383200DOI Listing
January 2005

Chemometrical classification of ephrin ligands and Eph kinases using GRID/CPCA approach.

J Chem Inf Comput Sci 2003 May-Jun;43(3):1004-10

Rammelkamp Center for Research, MetroHealth Campus, Case Western Reserve University School of Medicine, 2500 MetroHealth Drive, Cleveland, Ohio 44109, USA.

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http://dx.doi.org/10.1021/ci0256586DOI Listing
October 2003

EphA kinase activation regulates HGF-induced epithelial branching morphogenesis.

J Cell Biol 2003 Sep;162(7):1281-92

Rammelkamp Center for Research, MetroHealth Campus, Cleveland, OH 44109, USA.

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http://dx.doi.org/10.1083/jcb.200304018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173949PMC
September 2003

EphrinA1 inactivates integrin-mediated vascular smooth muscle cell spreading via the Rac/PAK pathway.

J Cell Sci 2003 Apr;116(Pt 7):1367-76

Institute of Signaling, Developmental Biology and Cancer Research, CNRS-UMR 6543, Centre Antoine Lacassagne, 33 Avenue de Valombrose, 06189 Nice, France.

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April 2003

Fas activation induces renal tubular epithelial cell beta 8 integrin expression and function in the absence of apoptosis.

J Biol Chem 2002 Dec 24;277(49):47826-33. Epub 2002 Sep 24.

Department of Medicine, Rammelkamp Center for Education and Research, MetroHealth Medical Center Campus, Case Western Reserve University School of Medicine, Cleveland, Ohio 44109-1998, USA.

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http://dx.doi.org/10.1074/jbc.M204901200DOI Listing
December 2002

EphB1 associates with Grb7 and regulates cell migration.

J Biol Chem 2002 Nov 9;277(47):45655-61. Epub 2002 Sep 9.

Department of Molecular Medicine, Cornell University, Ithaca, New York 14853, USA.

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http://dx.doi.org/10.1074/jbc.M203165200DOI Listing
November 2002