Bing-Hua Jiang

Bing-Hua Jiang

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Bing-Hua Jiang

Publications by authors named "Bing-Hua Jiang"

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PTEN Suppresses Glycolysis by Dephosphorylating and Inhibiting Autophosphorylated PGK1.

Mol Cell 2019 11 3;76(3):516-527.e7. Epub 2019 Sep 3.

Zhejiang Provincial Key Laboratory of Pancreatic Disease, The First Affiliated Hospital, and Institute of Translational Medicine, Zhejiang University School of Medicine, Hangzhou, Zhejiang 310029, China. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2019.08.006DOI Listing
November 2019

MiR-199a Inhibits Tumor Growth and Attenuates Chemoresistance by Targeting K-RAS via AKT and ERK Signalings.

Front Oncol 2019 15;9:1071. Epub 2019 Oct 15.

Institute of Medical and Pharmaceutical Sciences, The Academy of Medical Sciences, Zhengzhou University, Zhengzhou, China.

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http://dx.doi.org/10.3389/fonc.2019.01071DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6803549PMC
October 2019

Suppression of miR-143 contributes to overexpression of IL-6, HIF-1α and NF-κB p65 in Cr(VI)-induced human exposure and tumor growth.

Toxicol Appl Pharmacol 2019 Sep 29;378:114603. Epub 2019 May 29.

Department of Pathology, Carver College of Medicine, the University of Iowa, IA 52242, USA. Electronic address:

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http://dx.doi.org/10.1016/j.taap.2019.114603DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6897354PMC
September 2019

Arsenic-induced metabolic shift triggered by the loss of miR-199a-5p through Sp1-dependent DNA methylation.

Toxicol Appl Pharmacol 2019 Sep 3;378:114606. Epub 2019 Jun 3.

Department of Pathology, Carver College of Medicine, University of Iowa, Iowa City, IW 52242, United States of America. Electronic address:

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http://dx.doi.org/10.1016/j.taap.2019.114606DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6788774PMC
September 2019

2 deficiency induces teratozoospermia and male infertility through p53/PERP-mediated apoptosis in testis.

Asian J Androl 2019 Sep 6. Epub 2019 Sep 6.

Department of Pathology, Nanjing Medical University, Nanjing 210029, China.

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http://dx.doi.org/10.4103/aja.aja_76_19DOI Listing
September 2019

Apigenin Inhibits IL-6 Transcription and Suppresses Esophageal Carcinogenesis.

Front Pharmacol 2019 11;10:1002. Epub 2019 Sep 11.

The First Affiliated Hospital of Zhengzhou University, Zhengzhou University, Zhengzhou, Henan, China.

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http://dx.doi.org/10.3389/fphar.2019.01002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6749068PMC
September 2019

Optimization of Baccatin III Production by Cross-Linked Enzyme Aggregate of Taxoid 10β-O-Acetyltransferase.

Mol Biotechnol 2019 Jul;61(7):498-505

College of Food Science, Institute of Food Biotechnology, South China Agricultural University, Guangzhou, 510640, Guangdong, China.

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http://dx.doi.org/10.1007/s12033-019-00179-1DOI Listing
July 2019

Activity Essential Residue Analysis of Taxoid 10β-O-Acetyl Transferase for Enzymatic Synthesis of Baccatin.

Appl Biochem Biotechnol 2018 Dec 25;186(4):949-959. Epub 2018 May 25.

College of Food Science & Institute of Food Biotechnology, South China Agricultural University, 483 Wu-Shan Road, Tian-He District, Guangzhou, 510640, Guangdong, China.

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http://link.springer.com/10.1007/s12010-018-2789-0
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http://dx.doi.org/10.1007/s12010-018-2789-0DOI Listing
December 2018

Hypoxia-mediated mitochondria apoptosis inhibition induces temozolomide treatment resistance through miR-26a/Bad/Bax axis.

Cell Death Dis 2018 11 13;9(11):1128. Epub 2018 Nov 13.

Key Laboratory of Human Functional Genomics of Jiangsu Province, and Department of Pathology, Nanjing Medical University, Nanjing, Jiangsu, China.

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http://www.nature.com/articles/s41419-018-1176-7
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http://dx.doi.org/10.1038/s41419-018-1176-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6233226PMC
November 2018

Enhanced catalytic activities and modified substrate preferences for taxoid 10β-O-acetyl transferase mutants by engineering catalytic histidine residues.

Biotechnol Lett 2018 Aug 4;40(8):1245-1251. Epub 2018 Jun 4.

College of Food Science & Institute of Food Biotechnology, South China Agricultural University, Guangzhou, 510640, Guangdong, China.

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http://link.springer.com/10.1007/s10529-018-2573-9
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http://dx.doi.org/10.1007/s10529-018-2573-9DOI Listing
August 2018

K2 and K2*: efficient alignment-free sequence similarity measurement based on Kendall statistics.

Bioinformatics 2018 05;34(10):1682-1689

Department of Software engineering, College of Mathematics and Informatics, Fujian Normal University, Fuzhou 350108, China.

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http://dx.doi.org/10.1093/bioinformatics/btx809DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355110PMC
May 2018

SSAW: A new sequence similarity analysis method based on the stationary discrete wavelet transform.

BMC Bioinformatics 2018 05 2;19(1):165. Epub 2018 May 2.

College of Mathematics and Informatics, Fujian Normal University, Fuzhou, 350108, People's Republic of China.

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http://dx.doi.org/10.1186/s12859-018-2155-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5930706PMC
May 2018

Insulin-like growth factor-I induces chemoresistence to docetaxel by inhibiting miR-143 in human prostate cancer.

Oncotarget 2017 Dec 9;8(63):107157-107166. Epub 2017 Nov 9.

State Key Laboratory of Reproductive Medicine, Key Laboratory of Human Functional Genomics of Jiangsu Province, Jiangsu Key Laboratory of Cancer Biomarkers, Prevention, and Treatment Department of Pathology, Cancer Center, Nanjing Medical University, Nanjing, China.

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http://dx.doi.org/10.18632/oncotarget.22362DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5739804PMC
December 2017

IGF-1-mediated PKM2/β-catenin/miR-152 regulatory circuit in breast cancer.

Sci Rep 2017 Nov 21;7(1):15897. Epub 2017 Nov 21.

State Key Laboratory of Reproductive Medicine, Key Laboratory of Human Functional Genomics of Jiangsu Province, Collaborative Innovation Center for Cancer Personalized Medicine, Jiangsu Key Laboratory of Cancer Biomarkers, Prevention, and Treatment, Cancer Center, and Department of Pathology, Nanjing Medical University, Nanjing, Jiangsu, China.

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http://www.nature.com/articles/s41598-017-15607-y
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http://dx.doi.org/10.1038/s41598-017-15607-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698474PMC
November 2017

Phosphoglycerate Kinase 1 Phosphorylates Beclin1 to Induce Autophagy.

Mol Cell 2017 Mar 23;65(5):917-931.e6. Epub 2017 Feb 23.

Brain Tumor Center and Department of Neuro-Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX 77030, USA; The University of Texas Graduate School of Biomedical Sciences at Houston, Houston, TX 77030, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2017.01.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5389741PMC
March 2017

MiR-34a modulates ErbB2 in breast cancer.

Cell Biol Int 2017 Jan 1;41(1):93-101. Epub 2016 Dec 1.

Institute of Molecular and Chemical Biology, East China Normal University, North Zhongshan Road, Shanghai, 200062, China.

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http://dx.doi.org/10.1002/cbin.10700DOI Listing
January 2017

MiRNA-145 increases therapeutic sensibility to gemcitabine treatment of pancreatic adenocarcinoma cells.

Oncotarget 2016 Oct;7(43):70857-70868

Department of Laboratory Medicine, Huashan Hospital of Fudan University, Shanghai, China.

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http://dx.doi.org/10.18632/oncotarget.12268DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5342594PMC
October 2016

Cyclooxygenase-2 induced β1-integrin expression in NSCLC and promoted cell invasion via the EP1/MAPK/E2F-1/FoxC2 signal pathway.

Sci Rep 2016 Sep 22;6:33823. Epub 2016 Sep 22.

Cancer Center, Department of Pathology, Nanjing Medical University, Nanjing 210029, P.R. China.

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http://dx.doi.org/10.1038/srep33823DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5031967PMC
September 2016

miR-195 inhibits tumor growth and angiogenesis through modulating IRS1 in breast cancer.

Biomed Pharmacother 2016 May 17;80:95-101. Epub 2016 Mar 17.

Department of Chemistry and Molecular Engineering, East China Normal University, Shanghai, China. Electronic address:

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http://dx.doi.org/10.1016/j.biopha.2016.03.007DOI Listing
May 2016

Role and mechanism of miR-222 in arsenic-transformed cells for inducing tumor growth.

Oncotarget 2016 Apr;7(14):17805-14

State Key Laboratory of Reproductive Medicine, Department of Pathology, and Collaborative Innovation Center for Cancer Personalized Medicine, Cancer Center, Nanjing Medical University, Nanjing, Jiangsu, China.

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http://dx.doi.org/10.18632/oncotarget.7525DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4951251PMC
April 2016

Interplay between Reactive oxygen Species and MicroRNAs in Cancer.

Curr Pharmacol Rep 2016 Apr 9;2(2):82-90. Epub 2016 Feb 9.

Department of Pathology, Anatomy and Cell Biology, Thomas Jefferson University, Philadelphia, USA.

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http://dx.doi.org/10.1007/s40495-016-0051-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4894750PMC
April 2016

Downregulation of ATG14 by EGR1-MIR152 sensitizes ovarian cancer cells to cisplatin-induced apoptosis by inhibiting cyto-protective autophagy.

Autophagy 2015 ;11(2):373-84

a State Key Lab of Reproductive Medicine and Department of Pathology ; Cancer Center ; Collaborative Innovation Center for Cancer Personalized Medicine; Nanjing Medical University ; Nanjing , China.

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http://www.tandfonline.com/doi/full/10.1080/15548627.2015.10
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http://dx.doi.org/10.1080/15548627.2015.1009781DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4502709PMC
January 2016

MicroRNA-497 inhibits tumor growth and increases chemosensitivity to 5-fluorouracil treatment by targeting KSR1.

Oncotarget 2016 Jan;7(3):2660-71

State Key Lab of Reproductive Medicine, Collaborative Innovation Center for Cancer Personalized Medicine, Department of Pathology, Nanjing Medical University, Nanjing, China.

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http://dx.doi.org/10.18632/oncotarget.6545DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4823062PMC
January 2016

GSK-3β regulates tumor growth and angiogenesis in human glioma cells.

Oncotarget 2015 Oct;6(31):31901-15

State Key Lab of Reproductive Medicine, Department of Pathology and Collaborative Innovation Center for Cancer Personalized Medicine, Cancer Center, Nanjing Medical University, Nanjing 210029, China.

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http://www.oncotarget.com/fulltext/5043
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http://dx.doi.org/10.18632/oncotarget.5043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4741649PMC
October 2015

Primary cN0 lip squamous cell carcinoma and elective neck dissection: Systematic review and meta-analysis.

Head Neck 2015 Sep 21;37(9):1392-400. Epub 2014 Jul 21.

Department of Plastic and Reconstructive Surgery, 2nd Affiliated Hospital of Jiamusi University, Jiamusi City, Heilongjiang, People's Republic of China.

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http://doi.wiley.com/10.1002/hed.23772
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http://dx.doi.org/10.1002/hed.23772DOI Listing
September 2015

MiR-497 decreases cisplatin resistance in ovarian cancer cells by targeting mTOR/P70S6K1.

Oncotarget 2015 Sep;6(28):26457-71

Cancer Center, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

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http://www.oncotarget.com/fulltext/4762
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http://dx.doi.org/10.18632/oncotarget.4762DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4694914PMC
September 2015

Oral administration of apigenin inhibits metastasis through AKT/P70S6K1/MMP-9 pathway in orthotopic ovarian tumor model.

Int J Mol Sci 2012 13;13(6):7271-82. Epub 2012 Jun 13.

State Key Lab of Reproductive Medicine, and Department of Pathology, Cancer Center, Nanjing Medical University, Nanjing, 210029, China; E-Mails: (J.H.); (Q.X.); (M.W.); (C.L.); (X.Q.); (Z.S.).

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http://www.mdpi.com/1422-0067/13/6/7271
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http://dx.doi.org/10.3390/ijms13067271DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3397525PMC
August 2015

Tungsten Carbide-Cobalt Nanoparticles Induce Reactive Oxygen Species, AKT, ERK, AP-1, NF-κB, VEGF, and Angiogenesis.

Biol Trace Elem Res 2015 Jul 19;166(1):57-65. Epub 2015 Apr 19.

Department of Pathology, Anatomy and Cell Biology, Thomas Jefferson University, Philadelphia, PA, USA,

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http://dx.doi.org/10.1007/s12011-015-0331-6DOI Listing
July 2015

Network analysis of circular permutations in multidomain proteins reveals functional linkages for uncharacterized proteins.

Cancer Inform 2014 19;13(Suppl 5):109-24. Epub 2015 Feb 19.

Faculty of Software, Fujian Normal University, Fuzhou, Fujian, China.

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http://journals.sagepub.com/doi/10.4137/CIN.S14059
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http://dx.doi.org/10.4137/CIN.S14059DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4338801PMC
March 2015

Low miR-145 expression level is associated with poor pathological differentiation and poor prognosis in non-small cell lung cancer.

Biomed Pharmacother 2015 Feb 19;69:301-5. Epub 2014 Dec 19.

Department of Oncology, First Affiliated Hospital of Nanjing Medical University, Nanjing 210029, Jiangsu Province, China; Collaborative Innovation Center For Cancer Personalized Medicine, Nanjing Medical University, Nanjing , 210029 Jiangsu Province, China. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S07533322140021
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http://dx.doi.org/10.1016/j.biopha.2014.12.019DOI Listing
February 2015

Insulin regulates glucose consumption and lactate production through reactive oxygen species and pyruvate kinase M2.

Oxid Med Cell Longev 2014 8;2014:504953. Epub 2014 May 8.

Department of Pathology, State Key Lab of Reproductive Medicine, Cancer Center, Nanjing Medical University, Nanjing 210029, China ; Department of Pathology, Anatomy and Cell Biology, Thomas Jefferson University, Philadelphia, PA 19107, USA.

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http://downloads.hindawi.com/journals/omcl/2014/504953.pdf
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http://www.hindawi.com/journals/omcl/2014/504953/
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http://dx.doi.org/10.1155/2014/504953DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4034658PMC
December 2014

MiR-124 governs glioma growth and angiogenesis and enhances chemosensitivity by targeting R-Ras and N-Ras.

Neuro Oncol 2014 Oct 25;16(10):1341-53. Epub 2014 May 25.

Department of Neurosurgery, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China (Z.S., X.W., Y.Y., N.L.); State Key Lab of Reproductive Medicine, Department of Pathology, and Cancer Center, Nanjing Medical University, Nanjing, China (Z.S., Q.C., C.L., L.W., X.Q., C.J., X.L., B.-H.J.); Department of Pathology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China (H.L.); Department of Neurosurgery, Tianjin Medical University General Hospital, Tianjin, China (C.K.); Department of Neurosurgery, Tiantan Hospital, Capital Medical University, Beijing, China (T.J.); Department of Pathology, Anatomy and Cell Biology, Thomas Jefferson University, Philadelphia, Pennsylvania (L.-Z.L., B.-H.J.).

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http://dx.doi.org/10.1093/neuonc/nou084DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4165420PMC
October 2014

MiR-143 acts as a tumor suppressor by targeting N-RAS and enhances temozolomide-induced apoptosis in glioma.

Oncotarget 2014 Jul;5(14):5416-27

State Key Lab of Reproductive Medicine, Department of Pathology, Nanjing Medical University, Nanjing, China. Department of Pathology, Anatomy and Cell Biology, Thomas Jefferson University, Philadelphia, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4170647PMC
http://dx.doi.org/10.18632/oncotarget.2116DOI Listing
July 2014

Chronic arsenic exposure and angiogenesis in human bronchial epithelial cells via the ROS/miR-199a-5p/HIF-1α/COX-2 pathway.

Environ Health Perspect 2014 Mar 10;122(3):255-61. Epub 2014 Jan 10.

State Key Lab of Reproductive Medicine, Department of Pathology, Nanjing Medical University, Nanjing, People's Republic of China.

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http://ehp.niehs.nih.gov/1307545/
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http://dx.doi.org/10.1289/ehp.1307545DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3948041PMC
March 2014

NADPH oxidase subunit p22(phox)-mediated reactive oxygen species contribute to angiogenesis and tumor growth through AKT and ERK1/2 signaling pathways in prostate cancer.

Biochim Biophys Acta 2013 Dec 8;1833(12):3375-3385. Epub 2013 Oct 8.

State Key Lab of Reproductive Medicine, and Department of Pathology, Cancer Center, Nanjing Medical, Nanjing 210029, China; Department of Pathology, Anatomy and Cell Biology, Kimmel Cancer Center, Thomas Jefferson University, Philadelphia, PA 19107, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bbamcr.2013.09.018DOI Listing
December 2013

MicroRNA-26a promotes tumor growth and angiogenesis in glioma by directly targeting prohibitin.

CNS Neurosci Ther 2013 Oct 22;19(10):804-12. Epub 2013 Jul 22.

Department of Pathology, Jiangsu Key Lab of Cancer Biomarkers, Prevention and Treatment, Cancer Center, Nanjing Medical University, Nanjing, China.

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http://dx.doi.org/10.1111/cns.12149DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6493457PMC
October 2013

Roles and mechanism of miR-199a and miR-125b in tumor angiogenesis.

PLoS One 2013 20;8(2):e56647. Epub 2013 Feb 20.

State Key Lab of Reproductive Medicine, Department of Pathology, Cancer Center, Nanjing Medical University, Nanjing, Jiangsu, People's Republic of China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0056647PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3577861PMC
September 2013

Repression of miR-143 mediates Cr (VI)-induced tumor angiogenesis via IGF-IR/IRS1/ERK/IL-8 pathway.

Toxicol Sci 2013 Jul 7;134(1):26-38. Epub 2013 Jun 7.

Department of Pathology, Thomas Jefferson University, Philadelphia, PA, USA.

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http://dx.doi.org/10.1093/toxsci/kft101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3693131PMC
July 2013

MicroRNA-143 inhibits tumor growth and angiogenesis and sensitizes chemosensitivity to oxaliplatin in colorectal cancers.

Cell Cycle 2013 May 8;12(9):1385-94. Epub 2013 Apr 8.

Department of Pathology, State Key Lab of Reproductive Medicine and Cancer Center, Nanjing Medical University, Nanjing, China.

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http://dx.doi.org/10.4161/cc.24477DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674066PMC
May 2013

Roles of EGFR, PI3K, AKT, and mTOR in heavy metal-induced cancer.

Curr Cancer Drug Targets 2013 Mar;13(3):252-66

Department of Pathology, Anatomy, and Cell Biology, Thomas Jefferson University, 1020 Locust Street, Philadelphia, PA 19107, USA.

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http://dx.doi.org/10.2174/1568009611313030004DOI Listing
March 2013

Oxygen-independent regulation of HIF-1: novel involvement of PI3K/AKT/mTOR pathway in cancer.

Curr Cancer Drug Targets 2013 Mar;13(3):245-51

Department of Pathology, Anatomy and Cell Biology, Thomas Jefferson University, 1020 Locust Street, Room 336, Philadelphia, PA 19107, USA.

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http://dx.doi.org/10.2174/1568009611313030003DOI Listing
March 2013

PI3K/AKT and mTOR/p70S6K1 signaling pathways in human cancer.

Authors:
Bing-Hua Jiang

Curr Cancer Drug Targets 2013 Mar;13(3):233

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http://dx.doi.org/10.2174/1568009611313030001DOI Listing
March 2013

Kaempferol nanoparticles achieve strong and selective inhibition of ovarian cancer cell viability.

Int J Nanomedicine 2012 24;7:3951-9. Epub 2012 Jul 24.

Department of Biology, Natural Science Division, Alderson-Broaddus College, Philippi, WV 26416, USA.

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http://dx.doi.org/10.2147/IJN.S33670DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3410694PMC
February 2013

A regulatory circuit of miR-148a/152 and DNMT1 in modulating cell transformation and tumor angiogenesis through IGF-IR and IRS1.

J Mol Cell Biol 2013 Feb 29;5(1):3-13. Epub 2012 Aug 29.

State Key Lab of Reproductive Medicine, and Department of Pathology, Cancer Center, Nanjing Medical University, Nanjing 210029, China.

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http://dx.doi.org/10.1093/jmcb/mjs049DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3570052PMC
February 2013

Downregulation of miR-145 associated with cancer progression and VEGF transcriptional activation by targeting N-RAS and IRS1.

Biochim Biophys Acta 2013 Feb 29;1829(2):239-47. Epub 2012 Nov 29.

Department of Pathology, Nanjing Medical University, Nanjing, China.

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http://dx.doi.org/10.1016/j.bbagrm.2012.11.006DOI Listing
February 2013

Reactive oxygen species regulate ERBB2 and ERBB3 expression via miR-199a/125b and DNA methylation.

EMBO Rep 2012 Dec 13;13(12):1116-22. Epub 2012 Nov 13.

State Key Lab of Reproductive Medicine, Department of Pathology, Cancer Center, Nanjing Medical University, Nanjing 210029, PR China.

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http://dx.doi.org/10.1038/embor.2012.162DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3512405PMC
December 2012

Protein surface characterization using an invariant descriptor.

Int J Biomed Imaging 2011 22;2011:918978. Epub 2011 Nov 22.

Lane Department of Computer Science and Electrical Engineering, West Virginia University, Morgantown, WV 26506, USA.

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http://www.hindawi.com/journals/ijbi/2011/918978/
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http://dx.doi.org/10.1155/2011/918978DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3227456PMC
August 2012

AKT-dependent phosphorylation of Niban regulates nucleophosmin- and MDM2-mediated p53 stability and cell apoptosis.

EMBO Rep 2012 Jun 1;13(6):554-60. Epub 2012 Jun 1.

Brain Tumor Center and Department of Neuro-Oncology, Department of Systems Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas 77030, USA.

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http://embor.embopress.org/cgi/doi/10.1038/embor.2012.53
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http://dx.doi.org/10.1038/embor.2012.53DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3367238PMC
June 2012

Probabilistic suffix array: efficient modeling and prediction of protein families.

Bioinformatics 2012 May 19;28(10):1314-23. Epub 2012 Apr 19.

Faculty of Software, Fujian Normal University, Fuzhou 350108, China.

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http://dx.doi.org/10.1093/bioinformatics/bts121DOI Listing
May 2012

Lentivirus-mediated overexpression of microRNA-199a inhibits cell proliferation of human hepatocellular carcinoma.

Cell Biochem Biophys 2012 Jan;62(1):237-44

Cancer Center & Department of Pathology, Nanjing Medical University, Nanjing, China.

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http://dx.doi.org/10.1007/s12013-011-9263-8DOI Listing
January 2012

MiR-145 directly targets p70S6K1 in cancer cells to inhibit tumor growth and angiogenesis.

Nucleic Acids Res 2012 Jan 14;40(2):761-74. Epub 2011 Sep 14.

State Key lab of Reproductive Medicine, and Department of Pathology, Cancer Center, Nanjing Medical University, Nanjing, China.

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https://academic.oup.com/nar/article-lookup/doi/10.1093/nar/
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http://dx.doi.org/10.1093/nar/gkr730DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3258133PMC
January 2012

Role and mechanism of arsenic in regulating angiogenesis.

PLoS One 2011 8;6(6):e20858. Epub 2011 Jun 8.

Department of Pathology, Anatomy and Cell Biology, Thomas Jefferson University, Philadelphia, Pennsylvania, United States of America.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3110823PMC
October 2011

Arsenite induces cell transformation by reactive oxygen species, AKT, ERK1/2, and p70S6K1.

Biochem Biophys Res Commun 2011 Oct 24;414(3):533-8. Epub 2011 Sep 24.

Department of Pathology, Anatomy, and Cell Biology, Thomas Jefferson University, Philadelphia, PA 19107, United States.

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October 2011

Acacetin inhibits VEGF expression, tumor angiogenesis and growth through AKT/HIF-1α pathway.

Biochem Biophys Res Commun 2011 Sep 27;413(2):299-305. Epub 2011 Aug 27.

Department of Pathology, Anatomy & Cell Biology, Thomas Jefferson University, Philadelphia, PA, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3224790PMC
September 2011

MiR-21 induced angiogenesis through AKT and ERK activation and HIF-1α expression.

PLoS One 2011 Apr 22;6(4):e19139. Epub 2011 Apr 22.

Lab of Reproductive Medicine, Department of Pathology, Cancer Center, Nanjing Medical University, Nanjing, Jiangsu, China.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3081346PMC
April 2011

P70S6K 1 regulation of angiogenesis through VEGF and HIF-1alpha expression.

Biochem Biophys Res Commun 2010 Jul 25;398(3):395-9. Epub 2010 Jun 25.

Department of Pathology, Cancer Center, Nanjing Medical University, Nanjing 210029, China.

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http://dx.doi.org/10.1016/j.bbrc.2010.06.080DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928061PMC
July 2010

An algorithm for identifying novel targets of transcription factor families: application to hypoxia-inducible factor 1 targets.

Cancer Inform 2009 4;7:75-89. Epub 2009 Mar 4.

Lane Department of Computer Science and Electrical Engineering, West Virginia University, Morgantown, WV 26506, USA.

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http://dx.doi.org/10.4137/cin.s1054DOI Listing
May 2010

Kaempferol enhances cisplatin's effect on ovarian cancer cells through promoting apoptosis caused by down regulation of cMyc.

Cancer Cell Int 2010 May 11;10:16. Epub 2010 May 11.

Natural Science Division, Alderson-Broaddus College, Philippi, WV, 26416, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2885998PMC
May 2010

Phosphatidylinositol-3-kinase/akt regulates bleomycin-induced fibroblast proliferation and collagen production.

Am J Respir Cell Mol Biol 2010 Apr 11;42(4):432-41. Epub 2009 Jun 11.

West Virginia University, Department of Pharmaceutical Sciences, P.O. Box 9530, Morgantown, WV 26506, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2848736PMC
April 2010

Regulation of survivin by PI3K/Akt/p70S6K1 pathway.

Biochem Biophys Res Commun 2010 Apr 31;395(2):219-24. Epub 2010 Mar 31.

Department of Neurosurgery, The First Affiliated Hospital, Cancer Center, Nanjing Medical University, Nanjing 210029, China.

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April 2010

PI3K/PTEN signaling in angiogenesis and tumorigenesis.

Adv Cancer Res 2009 ;102:19-65

Mary Babb Randolph Cancer Center and Department of Microbiology, Immunology and Cell Biology, West Virginia University, Morgantown, West Virginia 26506, USA.

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http://dx.doi.org/10.1016/S0065-230X(09)02002-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2933405PMC
September 2009

Inhibition of cell growth and VEGF expression in ovarian cancer cells by flavonoids.

Nutr Cancer 2008 ;60(6):800-9

Natural Science Division, Alderson-Broaddus College, Philippi, WV 26416, USA.

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http://dx.doi.org/10.1080/01635580802100851DOI Listing
February 2009

Endothelial p70 S6 kinase 1 in regulating tumor angiogenesis.

Cancer Res 2008 Oct;68(19):8183-8

Department of Pathology, Lab of Reproductive Medicine, Cancer Center, Nanjing Medical University, Nanjing, Jiangsu, China.

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October 2008

Sulforaphane inhibited expression of hypoxia-inducible factor-1alpha in human tongue squamous cancer cells and prostate cancer cells.

Int J Cancer 2008 Sep;123(6):1255-61

Graduate Center for Toxicology, College of Medicine, The University of Kentucky, Lexington, KY 40503, USA.

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September 2008

Oxidative stress and chromium(VI) carcinogenesis.

J Environ Pathol Toxicol Oncol 2008 ;27(2):77-88

Graduate Center for Toxicology, College of Medicine, the University of Kentucky, Lexington, KY 40515, USA.

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July 2008

Glucose up-regulates HIF-1 alpha expression in primary cortical neurons in response to hypoxia through maintaining cellular redox status.

J Neurochem 2008 Jun 7;105(5):1849-60. Epub 2008 Feb 7.

College of Pharmacy, University of New Mexico, Albuquerque, New Mexico 87131, USA.

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http://dx.doi.org/10.1111/j.1471-4159.2008.05287.xDOI Listing
June 2008

Role of mTOR in anticancer drug resistance: perspectives for improved drug treatment.

Drug Resist Updat 2008 Jun 28;11(3):63-76. Epub 2008 Apr 28.

Department of Microbiology, Mary Babb Randolph Cancer Center, Immunology and Cell Biology, West Virginia University, Morgantown, WV 26506, USA.

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http://dx.doi.org/10.1016/j.drup.2008.03.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2519122PMC
June 2008

Makorin-2 is a neurogenesis inhibitor downstream of phosphatidylinositol 3-kinase/Akt (PI3K/Akt) signal.

J Biol Chem 2008 Mar 15;283(13):8486-95. Epub 2008 Jan 15.

Joint State Key Laboratory in Oncology in South China, Sun Yat-Sen University, Guangzhou, China.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2417189PMC
March 2008

The Fas death signaling pathway connecting reactive oxygen species generation and FLICE inhibitory protein down-regulation.

J Immunol 2008 Mar;180(5):3072-80

Pathology and Physiology Research Branch, National Institute for Occupational Safety and Health, Morgantown, WV 26505, USA.

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http://dx.doi.org/10.4049/jimmunol.180.5.3072DOI Listing
March 2008

AKT signaling in regulating angiogenesis.

Curr Cancer Drug Targets 2008 Feb;8(1):19-26

Lab. of Reproductive Medicine, Cancer Center, Nanjing Medical University, Nanjing 210029, Jiangsu, China.

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http://dx.doi.org/10.2174/156800908783497122DOI Listing
February 2008

PI3K/PTEN signaling in tumorigenesis and angiogenesis.

Biochim Biophys Acta 2008 Jan 29;1784(1):150-8. Epub 2007 Sep 29.

Cancer Center, Department of Pathology, Nanjing Medical University, Nanjing, Jiangsu, China.

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http://dx.doi.org/10.1016/j.bbapap.2007.09.008DOI Listing
January 2008

PI3K/PTEN/AKT signaling regulates prostate tumor angiogenesis.

Cell Signal 2007 Dec 15;19(12):2487-97. Epub 2007 Aug 15.

Mary Babb Randolph Cancer Center, Department of Microbiology, Immunology and Cell Biology, West Virginia University, Morgantown, WV 26506-9300, USA.

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http://dx.doi.org/10.1016/j.cellsig.2007.07.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2094004PMC
December 2007

Reactive oxygen species regulate angiogenesis and tumor growth through vascular endothelial growth factor.

Cancer Res 2007 Nov;67(22):10823-30

Mary Babb Randolph Cancer Center, West Virginia University, Morgantown, West Virginia 26506, USA.

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November 2007

Insulin-like growth factor-I induces cyclooxygenase-2 expression via PI3K, MAPK and PKC signaling pathways in human ovarian cancer cells.

Cell Signal 2007 Jul 8;19(7):1542-53. Epub 2007 Feb 8.

Mary Babb Randolph Cancer Center, Department of Microbiology, Immunology and Cell Biology, West Virginia University, Morgantown, WV 26506-9300, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1995421PMC
July 2007

PI3K activation is required for PMA-directed activation of cSrc by AFAP-110.

Am J Physiol Cell Physiol 2007 Jul 14;293(1):C119-32. Epub 2007 Mar 14.

The Mary Babb Randolph Cancer Center, Dept. of Microbiology, Immunology, and Cell Biology, West Virginia University, Morgantown, WV 26506-9300, USA.

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http://dx.doi.org/10.1152/ajpcell.00525.2006DOI Listing
July 2007

PI-3K/Akt signal pathway plays a crucial role in arsenite-induced cell proliferation of human keratinocytes through induction of cyclin D1.

J Cell Biochem 2007 Jul;101(4):969-78

Nelson Institute of Environmental Medicine, New York University School of Medicine, Tuxedo, NY 10987, USA.

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http://dx.doi.org/10.1002/jcb.21279DOI Listing
July 2007

Benzo[a]pyrene-3,6-dione inhibited VEGF expression through inducing HIF-1alpha degradation.

Biochem Biophys Res Commun 2007 Jun 9;357(2):517-23. Epub 2007 Apr 9.

Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China.

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June 2007

Insulin-like growth factor-I (IGF-I) induces epidermal growth factor receptor transactivation and cell proliferation through reactive oxygen species.

Free Radic Biol Med 2007 Jun 30;42(11):1651-60. Epub 2007 Jan 30.

The Institute for Nutritional Sciences, Shanghai Institute of Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China.

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June 2007

Mechanism of vascular endothelial growth factor expression mediated by cisplatin in human ovarian cancer cells.

Biochem Biophys Res Commun 2007 Jun 20;358(1):92-8. Epub 2007 Apr 20.

Laboratory of Reproductive Medicine, Cancer Center, Nanjing Medical University, Nanjing 210029, Jiangsu, China.

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http://dx.doi.org/10.1016/j.bbrc.2007.04.083DOI Listing
June 2007

Apigenin inhibits tumor angiogenesis through decreasing HIF-1alpha and VEGF expression.

Carcinogenesis 2007 Apr 27;28(4):858-64. Epub 2006 Oct 27.

The Institute for Nutritional Sciences, Shanghai Institute for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China.

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http://dx.doi.org/10.1093/carcin/bgl205DOI Listing
April 2007

Luteolin inhibits insulin-like growth factor 1 receptor signaling in prostate cancer cells.

Carcinogenesis 2007 Mar 25;28(3):713-23. Epub 2006 Oct 25.

The Institute for Nutritional Sciences, Shanghai Institute for Biological Sciences, Chinese Academy of Sciences, Graduate School of Chinese Academy of Sciences, Shanghai 200031, China.

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http://dx.doi.org/10.1093/carcin/bgl189DOI Listing
March 2007

Chrysin inhibits expression of hypoxia-inducible factor-1alpha through reducing hypoxia-inducible factor-1alpha stability and inhibiting its protein synthesis.

Mol Cancer Ther 2007 Jan;6(1):220-6

The Institute for Nutritional Sciences, Shanghai Institute for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China.

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http://dx.doi.org/10.1158/1535-7163.MCT-06-0526DOI Listing
January 2007