Bing Su

Bing Su

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Order-Preserving Optimal Transport for Distances between Sequences.

Authors:
Bing Su Gang Hua

IEEE Trans Pattern Anal Mach Intell 2019 Dec 14;41(12):2961-2974. Epub 2018 Sep 14.

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http://dx.doi.org/10.1109/TPAMI.2018.2870154DOI Listing
December 2019

A miRNA and a lncRNA.

Authors:
Bing Su

Biochem Biophys Res Commun 2019 Dec;520(4):701

Shanghai Institute of Immunology, Shanghai JiaoTong University School of Medicine, Department of Immunology and Microbiology, 280 South Chongqing Road, Building Five Room 1101, Shanghai, 200025, China. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2019.10.018DOI Listing
December 2019

Trio deep-sequencing does not reveal unexpected off-target and on-target mutations in Cas9-edited rhesus monkeys.

Nat Commun 2019 Dec 4;10(1):5525. Epub 2019 Dec 4.

State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, 650223, Kunming, China.

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http://dx.doi.org/10.1038/s41467-019-13481-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6892871PMC
December 2019

PLK4 deubiquitination by Spata2-CYLD suppresses NEK7-mediated NLRP3 inflammasome activation at the centrosome.

EMBO J 2019 Nov 25:e102201. Epub 2019 Nov 25.

Department of Immunology and Microbiology, the Minister of Education Key Laboratory of Cell Death and Differentiation, Shanghai Institute of Immunology, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

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http://dx.doi.org/10.15252/embj.2019102201DOI Listing
November 2019

GABARAPL1 Promotes AR+ Prostate Cancer Growth by Increasing FL-AR/AR-V Transcription Activity and Nuclear Translocation.

Front Oncol 2019 15;9:1254. Epub 2019 Nov 15.

Biomedical Research Institute, Shenzhen Peking University - The Hong Kong University of Science and Technology Medical Center, Shenzhen, China.

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http://dx.doi.org/10.3389/fonc.2019.01254DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6872515PMC
November 2019

Sin1/mTORC2 regulate B cell growth and metabolism by activating mTORC1 and Myc.

Cell Mol Immunol 2019 Sep 31;16(9):757-769. Epub 2019 Jan 31.

Shanghai Institute of Immunology, Department of Immunology and Microbiology, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China.

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http://dx.doi.org/10.1038/s41423-018-0185-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6804816PMC
September 2019

Fate Mapping via Ms4a3-Expression History Traces Monocyte-Derived Cells.

Cell 2019 Sep;178(6):1509-1525.e19

Shanghai Institute of Immunology, Department of Immunology and Microbiology, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China; Singapore Immunology Network, Agency for Science, Technology and Research, Singapore 138648, Singapore; Translational Immunology Institute, SingHealth Duke-NUS Academic Medical Centre, Singapore, Singapore. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2019.08.009DOI Listing
September 2019

Long-read assembly of the Chinese rhesus macaque genome and identification of ape-specific structural variants.

Nat Commun 2019 Sep 17;10(1):4233. Epub 2019 Sep 17.

State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, 650223, China.

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http://dx.doi.org/10.1038/s41467-019-12174-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6749001PMC
September 2019

Acylglycerol Kinase Maintains Metabolic State and Immune Responses of CD8 T Cells.

Cell Metab 2019 Aug 13;30(2):290-302.e5. Epub 2019 Jun 13.

Shanghai Institute of Immunology, Department of Immunology and Microbiology, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Shanghai Jiao Tong University School of Medicine, 280 South Chongqing Road, Shanghai 200025, China. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2019.05.016DOI Listing
August 2019

Host Prdx6 contributing to the intracellular survival of Brucella suis S2 strain.

BMC Vet Res 2019 Aug 22;15(1):304. Epub 2019 Aug 22.

Key Laboratory of Zoonosis Research, Ministry of Education, Institute of Zoonosis / College of Veterinary Medicine, Jilin University, Xi An Da Lu 5333, Changchun, 130062, China.

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http://dx.doi.org/10.1186/s12917-019-2049-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6704487PMC
August 2019

Synovial Fluid MicroRNA-210 as a Potential Biomarker for Early Prediction of Osteoarthritis.

Biomed Res Int 2019 29;2019:7165406. Epub 2019 Jul 29.

Xinxiang Key Lab of Translational Cancer Research, The Third Affiliated Hospital, Xinxiang Medical University, Xinxiang, Henan 453003, China.

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http://dx.doi.org/10.1155/2019/7165406DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6699254PMC
July 2019

Identifying Lineage-Specific Targets of Natural Selection by a Bayesian Analysis of Genomic Polymorphisms and Divergence from Multiple Species.

Mol Biol Evol 2019 06;36(6):1302-1315

CAS Key Laboratory of Genomic and Precision Medicine, Beijing Institute of Genomics, Chinese Academy of Sciences, Beijing, China.

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https://academic.oup.com/mbe/advance-article/doi/10.1093/mol
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http://dx.doi.org/10.1093/molbev/msz046DOI Listing
June 2019

A transgenic monkey model for the study of human brain evolution.

Authors:
Lei Shi Bing Su

Zool Res 2019 May 11;40(3):236-238. Epub 2019 Apr 11.

State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming Yunnan 650223, China.

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http://dx.doi.org/10.24272/j.issn.2095-8137.2019.031DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591165PMC
May 2019

Learning Low-Dimensional Temporal Representations with Latent Alignments.

Authors:
Bing Su Ying Wu

IEEE Trans Pattern Anal Mach Intell 2019 May 27. Epub 2019 May 27.

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http://dx.doi.org/10.1109/TPAMI.2019.2919303DOI Listing
May 2019

Construction and Activity Analyses of Single Functional Mouse Peroxiredoxin 6 (Prdx6).

J Vet Res 2019 Mar 22;63(1):99-105. Epub 2019 Mar 22.

Key Laboratory of Zoonosis Research, Institute of Zoonosis/College of Veterinary Medicine, Jilin University, Xi An Da Lu 5333, Changchun 130062, China.

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https://content.sciendo.com/view/journals/jvetres/63/1/artic
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http://dx.doi.org/10.2478/jvetres-2019-0004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458554PMC
March 2019

Metabolic regulation of T cell development by Sin1-mTORC2 is mediated by pyruvate kinase M2.

J Mol Cell Biol 2019 Feb;11(2):93-106

Shanghai Institute of Immunology, Department of Immunology and Microbiology, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

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https://academic.oup.com/jmcb/advance-article/doi/10.1093/jm
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http://dx.doi.org/10.1093/jmcb/mjy065DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6392101PMC
February 2019

Transcriptomic Landscape of von Economo Neurons in Human Anterior Cingulate Cortex Revealed by Microdissected-Cell RNA Sequencing.

Cereb Cortex 2019 02;29(2):838-851

State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China.

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http://dx.doi.org/10.1093/cercor/bhy286DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6319179PMC
February 2019

The Transcriptomic Landscape of Yaks Reveals Molecular Pathways for High Altitude Adaptation.

Genome Biol Evol 2019 01 1;11(1):72-85. Epub 2019 Jan 1.

State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China.

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http://dx.doi.org/10.1093/gbe/evy264DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6320679PMC
January 2019

MEKK3 coordinates with FBW7 to regulate WDR62 stability and neurogenesis.

PLoS Biol 2018 12 19;16(12):e2006613. Epub 2018 Dec 19.

State Key Laboratory of Molecular Developmental Biology, CAS Center for Excellence in Brain Science and Intelligence Technology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China.

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http://dx.plos.org/10.1371/journal.pbio.2006613
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http://dx.doi.org/10.1371/journal.pbio.2006613DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347294PMC
December 2018

Systems-level analysis of risk genes reveals the modular nature of schizophrenia.

Schizophr Res 2018 11 19;201:261-269. Epub 2018 May 19.

State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China; Center for Excellence in Animal Evolution and Genetics, Chinese Academy of Sciences, Kunming 650223, China. Electronic address:

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http://dx.doi.org/10.1016/j.schres.2018.05.015DOI Listing
November 2018

Inhibition of mTORC1 by lncRNA H19 via disrupting 4E-BP1/Raptor interaction in pituitary tumours.

Nat Commun 2018 11 5;9(1):4624. Epub 2018 Nov 5.

Department of Neurosurgery, Center of Pituitary Tumor, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, 200025, Shanghai, China.

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http://www.nature.com/articles/s41467-018-06853-3
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http://dx.doi.org/10.1038/s41467-018-06853-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218470PMC
November 2018

Metabolic control of regulatory T cell stability and function by TRAF3IP3 at the lysosome.

J Exp Med 2018 09 16;215(9):2463-2476. Epub 2018 Aug 16.

Shanghai Institute of Immunology, Department of Immunology and Microbiology, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Shanghai Jiao Tong University School of Medicine, Shanghai, China

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http://dx.doi.org/10.1084/jem.20180397DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6122976PMC
September 2018

Active mTORC2 Signaling in Naive T Cells Suppresses Bone Marrow Homing by Inhibiting CXCR4 Expression.

J Immunol 2018 08 22;201(3):908-915. Epub 2018 Jun 22.

Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06519;

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http://dx.doi.org/10.4049/jimmunol.1800529DOI Listing
August 2018

SENP3 maintains the stability and function of regulatory T cells via BACH2 deSUMOylation.

Nat Commun 2018 08 8;9(1):3157. Epub 2018 Aug 8.

Shanghai Institute of Immunology, Department of Immunology and Microbiology, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Shanghai Jiao Tong University School of Medicine, 280 South Chongqing Road, Shanghai, 200025, China.

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http://dx.doi.org/10.1038/s41467-018-05676-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6082899PMC
August 2018

Regulation of T cell immunity by cellular metabolism.

Front Med 2018 Aug 16;12(4):463-472. Epub 2018 Aug 16.

Shanghai Institute of Immunology, Department of Immunology and Microbiology, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Shanghai Jiao Tong University School of Medicine, Shanghai, 200025, China.

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http://dx.doi.org/10.1007/s11684-018-0668-2DOI Listing
August 2018

Autophagy and MHC-restricted antigen presentation.

Mol Immunol 2018 07 19;99:163-170. Epub 2018 May 19.

Aix Marseille Université, CNRS, INSERM, CIML, 13288 Marseille Cedex 9, France; Institute for Research in Biomedicine (IBiMed) and Ilidio Pinho Foundation, Department of Medical Sciences, University of Aveiro, 3810-193 Aveiro, Portugal. Electronic address:

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http://dx.doi.org/10.1016/j.molimm.2018.05.009DOI Listing
July 2018

Platelet MEKK3 regulates arterial thrombosis and myocardial infarct expansion in mice.

Blood Adv 2018 06;2(12):1439-1448

Department of Biochemistry and Molecular Cell Biology, Shanghai Key Laboratory of Tumor Microenvironment and Inflammation, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

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http://dx.doi.org/10.1182/bloodadvances.2017015149DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6020810PMC
June 2018

Darwinian positive selection on the pleiotropic effects of KITLG explain skin pigmentation and winter temperature adaptation in Eurasians.

Mol Biol Evol 2018 Jun 29. Epub 2018 Jun 29.

State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology,Chinese Academy of Sciences, Kunming, China.

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http://dx.doi.org/10.1093/molbev/msy136DOI Listing
June 2018

Integrated analysis supports ATXN1 as a schizophrenia risk gene.

Authors:
Jiewei Liu Bing Su

Schizophr Res 2018 05 19;195:298-305. Epub 2017 Oct 19.

State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, Yunnan, China. Electronic address:

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http://dx.doi.org/10.1016/j.schres.2017.10.010DOI Listing
May 2018

Heteroscedastic Max-min Distance Analysis for Dimensionality Reduction.

IEEE Trans Image Process 2018 May 21. Epub 2018 May 21.

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http://dx.doi.org/10.1109/TIP.2018.2836312DOI Listing
May 2018

Intestinal Epithelial Cell-Derived LKB1 Suppresses Colitogenic Microbiota.

J Immunol 2018 03 19;200(5):1889-1900. Epub 2018 Jan 19.

Shanghai Institute of Immunology, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China;

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http://dx.doi.org/10.4049/jimmunol.1700547DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6814173PMC
March 2018

mA mRNA methylation sustains Treg suppressive functions.

Cell Res 2018 Feb 5;28(2):253-256. Epub 2018 Jan 5.

Shanghai Institute of Immunology, Department of Microbiology and Immunology, Shanghai Jiao Tong University School of Medicine (SJTU-SM), Shanghai 200025, PR China.

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http://www.nature.com/doifinder/10.1038/cr.2018.7
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http://dx.doi.org/10.1038/cr.2018.7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5799823PMC
February 2018

Discriminative Dimensionality Reduction for Multi-Dimensional Sequences.

IEEE Trans Pattern Anal Mach Intell 2018 01 7;40(1):77-91. Epub 2017 Feb 7.

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http://dx.doi.org/10.1109/TPAMI.2017.2665545DOI Listing
January 2018

Unsupervised Hierarchical Dynamic Parsing and Encoding for Action Recognition.

IEEE Trans Image Process 2017 Dec 25;26(12):5784-5799. Epub 2017 Aug 25.

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http://dx.doi.org/10.1109/TIP.2017.2745212DOI Listing
December 2017

LRRK2 promotes the activation of NLRC4 inflammasome during Typhimurium infection.

J Exp Med 2017 Oct 18;214(10):3051-3066. Epub 2017 Aug 18.

Shanghai Institute of Immunology, Shanghai Jiao Tong University School of Medicine, Shanghai, China

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http://dx.doi.org/10.1084/jem.20170014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626397PMC
October 2017

SSeCKS/AKAP12 induces repulsion between human prostate cancer and microvessel endothelial cells through the activation of Semaphorin 3F.

Biochem Biophys Res Commun 2017 09 8;490(4):1394-1398. Epub 2017 Jul 8.

Xinxiang Key Lab of Translational Cancer Research, The Third Affiliated Hospital, Xinxiang Medical University, Xinxiang, Henan, China. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2017.07.043DOI Listing
September 2017

Discriminative Transformation for Multi-Dimensional Temporal Sequences.

IEEE Trans Image Process 2017 Jul 16;26(7):3579-3593. Epub 2017 May 16.

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http://dx.doi.org/10.1109/TIP.2017.2704438DOI Listing
July 2017

Differentiated demographic histories and local adaptations between Sherpas and Tibetans.

Genome Biol 2017 06 15;18(1):115. Epub 2017 Jun 15.

Chinese Academy of Sciences (CAS) Key Laboratory of Computational Biology, Max Planck Independent Research Group on Population Genomics, CAS-MPG Partner Institute for Computational Biology (PICB), Shanghai Institutes for Biological Sciences, CAS, Shanghai, 200031, China.

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http://dx.doi.org/10.1186/s13059-017-1242-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5472941PMC
June 2017

RIG-I antiviral signaling drives interleukin-23 production and psoriasis-like skin disease.

EMBO Mol Med 2017 05;9(5):589-604

Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Department of Immunology and Microbiology, Shanghai Institute of Immunology, Shanghai Jiao Tong University School of Medicine (SJTU-SM), Shanghai, China

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http://dx.doi.org/10.15252/emmm.201607027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5412807PMC
May 2017

Nek7 Protects Telomeres from Oxidative DNA Damage by Phosphorylation and Stabilization of TRF1.

Mol Cell 2017 Mar 16;65(5):818-831.e5. Epub 2017 Feb 16.

University of Pittsburgh Cancer Institute, University of Pittsburgh School of Medicine, 5117 Centre Avenue, Pittsburgh, PA 15213, USA; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Bridgeside Point II, 450 Technology Drive, Pittsburgh, PA 15219, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10972765173004
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http://dx.doi.org/10.1016/j.molcel.2017.01.015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5924698PMC
March 2017

Regional selection of the brain size regulating gene CASC5 provides new insight into human brain evolution.

Hum Genet 2017 02 22;136(2):193-204. Epub 2016 Nov 22.

State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, People's Republic of China.

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http://dx.doi.org/10.1007/s00439-016-1748-5DOI Listing
February 2017

Paeoniflorin Ameliorates Experimental Autoimmune Encephalomyelitis via Inhibition of Dendritic Cell Function and Th17 Cell Differentiation.

Sci Rep 2017 02 6;7:41887. Epub 2017 Feb 6.

Shanghai Institute of Immunology, Department of Immunology and Microbiology, Shanghai Jiao Tong University School of Medicine, Shanghai, PR China.

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http://dx.doi.org/10.1038/srep41887DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5292961PMC
February 2017

GABARAPL1 suppresses metastasis by counteracting PI3K/Akt pathway in prostate cancer.

Oncotarget 2017 Jan;8(3):4449-4459

Xinxiang Key Lab of Translational Cancer Research, The Third Affiliated Hospital, Xinxiang Medical University, Xinxiang, Henan, China.

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http://dx.doi.org/10.18632/oncotarget.13879DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354845PMC
January 2017

Sherpas share genetic variations with Tibetans for high-altitude adaptation.

Mol Genet Genomic Med 2017 Jan 23;5(1):76-84. Epub 2016 Nov 23.

State Key Laboratory of Genetic Resources and Evolution Kunming Institute of Zoology Chinese Academy of Sciences Kunming 650223 China.

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http://dx.doi.org/10.1002/mgg3.264DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5241213PMC
January 2017

GWAS-identified schizophrenia risk SNPs at TSPAN18 are highly diverged between Europeans and East Asians.

Am J Med Genet B Neuropsychiatr Genet 2016 12 17;171(8):1032-1040. Epub 2016 Jun 17.

State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China.

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http://dx.doi.org/10.1002/ajmg.b.32471DOI Listing
December 2016

Comparative Methylome Analyses Identify Epigenetic Regulatory Loci of Human Brain Evolution.

Mol Biol Evol 2016 11 25;33(11):2947-2959. Epub 2016 Aug 25.

School of Biological Sciences, Institute of Bioengineering and Bioscience, Georgia Institute of Technology, Atlanta, GA

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http://dx.doi.org/10.1093/molbev/msw176DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5062329PMC
November 2016

Age-related gene expression change of GABAergic system in visual cortex of rhesus macaque.

Gene 2016 Sep 16;590(2):227-33. Epub 2016 May 16.

State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, China. Electronic address:

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http://dx.doi.org/10.1016/j.gene.2016.05.010DOI Listing
September 2016

Ancestral Origins and Genetic History of Tibetan Highlanders.

Am J Hum Genet 2016 09 25;99(3):580-594. Epub 2016 Aug 25.

Key Laboratory of Computational Biology, Max Planck Independent Research Group on Population Genomics, CAS-MPG Partner Institute for Computational Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China; University of Chinese Academy of Sciences, Beijing 100049, China; School of Life Science and Technology, ShanghaiTech University, Shanghai 200031, China; Collaborative Innovation Center of Genetics and Development, Shanghai 200438, China. Electronic address:

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http://www.cell.com/ajhg/pdf/S0002-9297(16)30273-7.pdf
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http://dx.doi.org/10.1016/j.ajhg.2016.07.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5011065PMC
September 2016

Emergence and evolution of inter-specific segregating retrocopies in cynomolgus monkey (Macaca fascicularis) and rhesus macaque (Macaca mulatta).

Sci Rep 2016 09 7;6:32598. Epub 2016 Sep 7.

State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, China.

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http://dx.doi.org/10.1038/srep32598DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013489PMC
September 2016

Glaucocalyxin B induces apoptosis and autophagy in human cervical cancer cells.

Mol Med Rep 2016 Aug 27;14(2):1751-5. Epub 2016 Jun 27.

Xinxiang Key Lab of Translational Cancer Research, The Third Affiliated Hospital of Xinxiang Medical University, Xinxiang, Henan 453003, P.R. China.

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http://dx.doi.org/10.3892/mmr.2016.5450DOI Listing
August 2016

Biological relevance of fatty acyl heterogeneity to the neural membrane dynamics of rhesus macaques during normative aging.

Oncotarget 2016 08;7(35):55970-55989

State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing, China.

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http://dx.doi.org/10.18632/oncotarget.11190DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5302890PMC
August 2016

Application of the genome editing tool CRISPR/Cas9 in non-human primates.

Dongwuxue Yanjiu 2016 Jul;37(4):214-9

State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming Yunnan 650223, Chin.

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http://dx.doi.org/10.13918/j.issn.2095-8137.2016.4.214DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4980068PMC
July 2016

Characterization of Sin1 Isoforms Reveals an mTOR-Dependent and Independent Function of Sin1γ.

PLoS One 2015 11;10(8):e0135017. Epub 2015 Aug 11.

Key Laboratory of Cell Differentiation and Apoptosis of National Ministry of Education, Department of Pathophysiology, Shanghai Jiaotong University School of Medicine, Shanghai, 200025, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0135017PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4532406PMC
May 2016

Adaptive evolution of interleukin-3 (IL3), a gene associated with brain volume variation in general human populations.

Hum Genet 2016 Apr 13;135(4):377-392. Epub 2016 Feb 13.

Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, 650223, Yunnan, China.

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http://dx.doi.org/10.1007/s00439-016-1644-zDOI Listing
April 2016

The Long Noncoding RNA MEG3 Is Downregulated and Inversely Associated with VEGF Levels in Osteoarthritis.

Biomed Res Int 2015 21;2015:356893. Epub 2015 May 21.

Biomedical Research Institute, Shenzhen PKU-HKUST Medical Center, Shenzhen, Guangdong 518036, China.

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http://dx.doi.org/10.1155/2015/356893DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4454735PMC
March 2016

No association between schizophrenia susceptibility variants and macroscopic structural brain volume variation in healthy subjects.

Am J Med Genet B Neuropsychiatr Genet 2016 Mar 5;171B(2):160-8. Epub 2015 Oct 5.

Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences & Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China.

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http://dx.doi.org/10.1002/ajmg.b.32387DOI Listing
March 2016

Oncogenic K-ras confers SAHA resistance by up-regulating HDAC6 and c-myc expression.

Oncotarget 2016 Mar;7(9):10064-72

Shanghai Institute of Immunology, Shanghai Jiaotong University School of Medicine, Shanghai, China.

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http://dx.doi.org/10.18632/oncotarget.7134DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4891104PMC
March 2016

MEKK2 mediates an alternative β-catenin pathway that promotes bone formation.

Proc Natl Acad Sci U S A 2016 Mar 16;113(9):E1226-35. Epub 2016 Feb 16.

Department of Pathology and Laboratory Medicine Weill Cornell Medicine, New York, NY 10065;

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http://dx.doi.org/10.1073/pnas.1600813113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4780654PMC
March 2016

Impact of a cis-associated gene expression SNP on chromosome 20q11.22 on bipolar disorder susceptibility, hippocampal structure and cognitive performance.

Br J Psychiatry 2016 Feb 3;208(2):128-37. Epub 2015 Sep 3.

Ming Li, PhD, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China, and Lieber Institute for Brain Development, Johns Hopkins University, Baltimore, Maryland, USA; Xiong-jian Luo, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Mikael Landén, MD, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, and Section of Psychiatry and Neurochemistry, Sahlgrenska Academy at Gothenburg University, Gothenburg, Sweden; Sarah E. Bergen, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden, and Stanley Center for Psychiatric Research, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA; Christina M. Hultman, PhD, Department of Medical Epidemiology and Biostatistics, Karolinska Institute, Stockholm, Sweden; Xiao Li, MSc, Wen Zhang, PhD, Yong-Gang Yao, PhD, Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; Chen Zhang, PhD, Schizophrenia Program, Shanghai Mental Health Center, and Shanghai Jiao Tong University School of Medicine, Shanghai, China; Jiewei Liu, MSc, State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, and Kunming College of Life Science, University of Chinese Academy of Sciences, Kunming, Yunnan, China; Manuel Mattheisen, MD, Department of Biomedicine, Aarhus University, Aarhus C, Denmark; Sven Cichon, PhD, Division of Medical Genetics, University of Basel, Basel, Switzerland, Institute of Human Genetics and Department of Genomics, Life and Brain Center, University of Bonn, Bonn, and Institute of Neuroscience and Medicine (INM-1), Structural and Functional Organi

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http://bjp.rcpsych.org/cgi/doi/10.1192/bjp.bp.114.156976
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829352PMC
February 2016

HMOX2 Functions as a Modifier Gene for High-Altitude Adaptation in Tibetans.

Hum Mutat 2016 Feb 14;37(2):216-23. Epub 2015 Dec 14.

State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, 650223, China.

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http://dx.doi.org/10.1002/humu.22935DOI Listing
February 2016

Sex Biased Gene Expression Profiling of Human Brains at Major Developmental Stages.

Sci Rep 2016 Feb 16;6:21181. Epub 2016 Feb 16.

Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650500, China.

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http://dx.doi.org/10.1038/srep21181DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4754746PMC
February 2016

Recent Positive Selection Drives the Expansion of a Schizophrenia Risk Nonsynonymous Variant at SLC39A8 in Europeans.

Schizophr Bull 2016 Jan 25;42(1):178-90. Epub 2015 May 25.

Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences and Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; These authors contributed equally to this work. ML and XJL are co-corresponding authors who jointly directed this work.

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https://academic.oup.com/schizophreniabulletin/article-looku
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http://dx.doi.org/10.1093/schbul/sbv070DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4681542PMC
January 2016

Psychiatric genetics in China: achievements and challenges.

Mol Psychiatry 2016 Jan 20;21(1):4-9. Epub 2015 Oct 20.

Neuropsychology and Applied Cognitive Neuroscience Laboratory, Key Laboratory of Mental Health, Institute of Psychology, Chinese Academy of Sciences.

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http://dx.doi.org/10.1038/mp.2015.95DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4830695PMC
January 2016

Systematic Integration of Brain eQTL and GWAS Identifies ZNF323 as a Novel Schizophrenia Risk Gene and Suggests Recent Positive Selection Based on Compensatory Advantage on Pulmonary Function.

Schizophr Bull 2015 Nov 10;41(6):1294-308. Epub 2015 Mar 10.

Key Laboratory of Animal Models and Human Disease Mechanisms of the Chinese Academy of Sciences & Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan, China; CAS Center for Excellence in Brain Science, Chinese Academy of Sciences, Shanghai, 200031, China.

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http://dx.doi.org/10.1093/schbul/sbv017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4601704PMC
November 2015

Gabarapl1 mediates androgen-regulated autophagy in prostate cancer.

Tumour Biol 2015 Nov 7;36(11):8727-33. Epub 2015 Jun 7.

Biomedical Research Institute, Shenzhen Peking University-The Hong Kong University of Science and Technology Medical Center, No. 1120, Lianhua Road, Futian District, Shenzhen, Guangdong, 518036, China.

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http://dx.doi.org/10.1007/s13277-015-3542-8DOI Listing
November 2015

PtdIns(3,4,5)P3-Dependent Activation of the mTORC2 Kinase Complex.

Cancer Discov 2015 Nov 20;5(11):1194-209. Epub 2015 Aug 20.

Department of Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1158/2159-8290.CD-15-0460DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4631654PMC
November 2015

Genetic evidence of a recent Tibetan ancestry to Sherpas in the Himalayan region.

Sci Rep 2015 Nov 5;5:16249. Epub 2015 Nov 5.

State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming 650223, China.

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http://dx.doi.org/10.1038/srep16249DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4633682PMC
November 2015

Crosstalk between the TNF and IGF pathways enhances NF-κB activation and signaling in cancer cells.

Growth Horm IGF Res 2015 Oct 20;25(5):253-61. Epub 2015 Jul 20.

Dept of Medicine, McGill University and the McGill University Health Center, Canada; Dept of Surgery, McGill University and the McGill University Health Center, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ghir.2015.07.008DOI Listing
October 2015

EphA6 promotes angiogenesis and prostate cancer metastasis and is associated with human prostate cancer progression.

Oncotarget 2015 Sep;6(26):22587-97

Department of Laboratory Medicine, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai 200040, China.

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http://dx.doi.org/10.18632/oncotarget.4088DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4673184PMC
September 2015

A novel IL-17 signaling pathway controlling keratinocyte proliferation and tumorigenesis via the TRAF4-ERK5 axis.

J Exp Med 2015 Sep 7;212(10):1571-87. Epub 2015 Sep 7.

Department of Immunology, Department of Anatomical Pathology and Clinical Pathology, Department of Cancer Biology, Department of Dermatology, and Department of Plastic Surgery, Cleveland Clinic, Cleveland, OH 44195

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http://www.jem.org/lookup/doi/10.1084/jem.20150204
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http://dx.doi.org/10.1084/jem.20150204DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4577838PMC
September 2015

Circulating miR-126 is a potential biomarker to predict the onset of type 2 diabetes mellitus in susceptible individuals.

Biochem Biophys Res Commun 2015 Jul 17-24;463(1-2):60-3. Epub 2015 May 15.

Xinxiang Key Lab of Translational Cancer Research, The Third Affiliated Hospital, Xinxiang Medical University, Xinxiang, Henan 453003, China; Department of Epidemiology and Environmental Health, School of Public Health and Health Professions, The State University of New York, Buffalo, NY, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2015.05.017DOI Listing
August 2015

High concentrations of dextromethorphan result in false-positive in opiate immunoassay test.

Clin Chim Acta 2015 Aug 17;448:247. Epub 2015 Jul 17.

Clinical Toxicology Lab, Medlab, Inc., Buffalo, NY 14225, United States. Electronic address:

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http://dx.doi.org/10.1016/j.cca.2015.07.015DOI Listing
August 2015

Structure and vascular function of MEKK3-cerebral cavernous malformations 2 complex.

Nat Commun 2015 Aug 3;6:7937. Epub 2015 Aug 3.

Department of Microbiology and Immunology, Shanghai Institute of Immunology, Shanghai Jiao Tong University School of Medicine (SJTU-SM), Shanghai 200025, China.

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http://dx.doi.org/10.1038/ncomms8937DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526114PMC
August 2015

A 3.4-kb Copy-Number Deletion near EPAS1 Is Significantly Enriched in High-Altitude Tibetans but Absent from the Denisovan Sequence.

Am J Hum Genet 2015 Jul 11;97(1):54-66. Epub 2015 Jun 11.

Key Laboratory of Computational Biology, Max Planck Independent Research Group on Population Genomics, Partner Institute for Computational Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China; School of Life Science and Technology, ShanghaiTech University, Shanghai 200031, China; Collaborative Innovation Center of Genetics and Development, Shanghai 200438, China. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2015.05.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4572470PMC
July 2015

Targeted DNA damage at individual telomeres disrupts their integrity and triggers cell death.

Nucleic Acids Res 2015 Jul 16;43(13):6334-47. Epub 2015 Jun 16.

University of Pittsburgh Cancer Institute; University of Pittsburgh School of Medicine; 5117 Centre Avenue, Pittsburgh, PA 15213, USA Department of Microbiology and Molecular Genetics; University of Pittsburgh School of Medicine; 523 Bridgeside Point II, 450 Technology Drive, Pittsburgh, PA 15219, USA

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http://dx.doi.org/10.1093/nar/gkv598DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4513870PMC
July 2015

NF-κB-induced microRNA-31 promotes epidermal hyperplasia by repressing protein phosphatase 6 in psoriasis.

Nat Commun 2015 Jul 3;6:7652. Epub 2015 Jul 3.

1] Shanghai Institute of Immunology, Key Laboratory of Cell Differentiation and Apoptosis of Chinese Ministry of Education, Shanghai Jiao Tong University School of Medicine (SJTU-SM), Shanghai 200025, China [2] Shanghai Key Laboratory for Tumor Microenvironment and Inflammation, Shanghai Jiao Tong University School of Medicine (SJTU-SM), Shanghai 200025, China.

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http://dx.doi.org/10.1038/ncomms8652DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4506511PMC
July 2015

Estrogen regulation of microcephaly genes and evolution of brain sexual dimorphism in primates.

BMC Evol Biol 2015 Jun 30;15:127. Epub 2015 Jun 30.

State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, 32 East Jiao-Chang Road, Kunming, 650223, Yunnan, PR China.

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http://dx.doi.org/10.1186/s12862-015-0398-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4487212PMC
June 2015

A functional MiR-124 binding-site polymorphism in IQGAP1 affects human cognitive performance.

PLoS One 2014 15;9(9):e107065. Epub 2014 Sep 15.

State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, China.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0107065PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4164536PMC
May 2015

Chronic trimethyltin chloride exposure and the development of kidney stones in rats.

J Appl Toxicol 2015 May 16;35(5):500-7. Epub 2014 Sep 16.

Department of Epidemiology and Environmental Health, the State University of New York, Buffalo, USA; Department of Pharmacology and Toxicology, the State University of New York, Buffalo, USA; Guangdong Medical Laboratory Animal Center, Foshan, Guangdong, China.

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http://dx.doi.org/10.1002/jat.3054DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4437662PMC
May 2015

MDA-9 and GRP78 as potential diagnostic biomarkers for early detection of melanoma metastasis.

Tumour Biol 2015 Apr 6;36(4):2973-82. Epub 2014 Dec 6.

Department of Laboratory Medicine, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, 200040, China.

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http://dx.doi.org/10.1007/s13277-014-2930-9DOI Listing
April 2015

Characterization of a halophilic heterotrophic nitrification-aerobic denitrification bacterium and its application on treatment of saline wastewater.

Bioresour Technol 2015 Mar 22;179:421-428. Epub 2014 Dec 22.

Research Center of Water Treatment Engineering, Jimei University, Xiamen 361021, PR China; School of Food and Biological Engineering, Jimei University, Xiamen 361021, PR China.

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http://dx.doi.org/10.1016/j.biortech.2014.12.057DOI Listing
March 2015

Allelic variation at 5-HTTLPR is associated with brain morphology in a Chinese population.

Psychiatry Res 2015 Mar 30;226(1):399-402. Epub 2015 Jan 30.

State Key Laboratory of Genetic Resources and Evolution, Kunming Institute of Zoology, Chinese Academy of Sciences, Kunming, Yunnan, China. Electronic address:

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http://dx.doi.org/10.1016/j.psychres.2015.01.022DOI Listing
March 2015

Rapamycin inhibits mSin1 phosphorylation independently of mTORC1 and mTORC2.

Oncotarget 2015 Feb;6(6):4286-98

Department of Biochemistry and Molecular Biology, Louisiana State University Health Sciences Center, Shreveport, LA, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4414190PMC
http://dx.doi.org/10.18632/oncotarget.3006DOI Listing
February 2015

Regulatory effects of a Mnk2-eIF4E feedback loop during mTORC1 targeting of human medulloblastoma cells.

Oncotarget 2014 Sep;5(18):8442-51

Robert H. Lurie Comprehensive Cancer Center and Division of Hematology- Oncology, Feinberg School of Medicine, Northwestern University, Chicago, IL,USA; Department of Medicine, Jesse Brown VA Medical Center, Chicago, IL, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4226695PMC
http://dx.doi.org/10.18632/oncotarget.2319DOI Listing
September 2014