Bin T Teh

Bin T Teh

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Bin T Teh

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Osteoblast-specific deletion of Hrpt2/Cdc73 results in high bone mass and increased bone turnover.

Bone 2017 05 3;98:68-78. Epub 2017 Apr 3.

Program for Skeletal Disease and Tumor Microenvironment, Grand Rapids, MI, USA; Center for Cancer and Cell Biology, Van Andel Research Institute, Grand Rapids, MI, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bone.2016.12.006DOI Listing
May 2017

A germline mutation in PBRM1 predisposes to renal cell carcinoma.

J Med Genet 2015 Jun 24;52(6):426-30. Epub 2015 Apr 24.

Ecole Pratique des Hautes Etudes, Paris, France Laboratoire de Génétique Oncologique EPHE, INSERM U753, Villejuif, France Faculté de Médecine Université Paris-Sud, Le Kremlin-Bicêtre, France.

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http://dx.doi.org/10.1136/jmedgenet-2014-102912DOI Listing
June 2015

Whole-exome sequencing studies of parathyroid carcinomas reveal novel PRUNE2 mutations, distinctive mutational spectra related to APOBEC-catalyzed DNA mutagenesis and mutational enrichment in kinases associated with cell migration and invasion.

J Clin Endocrinol Metab 2015 Feb 11;100(2):E360-4. Epub 2014 Nov 11.

Laboratory of Cancer Epigenome (W.Y., H.L.H., A.G., D.H., S.L.P., C.K.O., B.T.T.), Division of Medical Sciences, National Cancer Centre Singapore, 169610 Singapore; Division of Cancer and Stem Cell Biology (W.Y., J.R.M., H.L.H., D.H., S.L.P., C.K.O., S.G.R., P.T., B.T.T.), Duke-National University of Singapore Graduate Medical School, 169857 Singapore; National University of Singapore Graduate School for Integrative Sciences and Engineering (W.Y.), 117456 Singapore; Academic Endocrine Unit, Nuffield Department of Clinical Medicine (M.S., P.N., R.V.T.), Oxford Centre for Diabetes, Endocrinology and Metabolism (OCDEM), University of Oxford, OX3 7LJ Oxford, United Kingdom; Department of Pathology (R.v.E., D.R., T.v.W., H.M.), Leiden University Medical Center, 2333 ZA Leiden, The Netherlands; Molecular Endocrinology Group, Molecular Pathobiology Research Centre Unit (U.I.P.M.) (B.C.) of the Portuguese Institute of Oncology from Lisbon Francisco Gentil (IPOLFG) and Chronic Diseases Research Centre (CEDOC), Faculty of Medical Sciences (FCM), New University of Lisbon (UNL), 1099-023 Lisbon, Portugal; Genome Institute of Singapore (P.T.), 138672 Singapore; and Cancer Science Institute of Singapore (P.T., B.T.T.), National University of Singapore, 117599 Singapore.

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http://dx.doi.org/10.1210/jc.2014-3238DOI Listing
February 2015

Glypican 3 overexpression in primary and metastatic Wilms tumors.

Virchows Arch 2015 Jan 4;466(1):67-76. Epub 2014 Nov 4.

Department of Pathology, University of Washington, 325 9th Ave, Seattle, WA, 98104, USA,

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http://dx.doi.org/10.1007/s00428-014-1669-4DOI Listing
January 2015

Molecular targets on the horizon for kidney and urothelial cancer.

Nat Rev Clin Oncol 2013 Oct 27;10(10):557-70. Epub 2013 Aug 27.

Dana-Farber and Brigham and Women's Cancer Center, Harvard Medical School, 450 Brookline Avenue, Boston, MA 02215, USA and Hospital del Mar-IMIM-IMAS, Doctor Aiguader 88, 08003 Barcelona, Spain.

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http://dx.doi.org/10.1038/nrclinonc.2013.155DOI Listing
October 2013

Gene profiling suggests a common evolution of bladder cancer subtypes.

BMC Med Genomics 2013 Oct 17;6:42. Epub 2013 Oct 17.

Department of Pathology, University of California at San Diego, 9500 Gilman Drive, MC 0612, La Jolla, CA 92093, USA.

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http://dx.doi.org/10.1186/1755-8794-6-42DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4015777PMC
October 2013

Folliculin interacts with p0071 (plakophilin-4) and deficiency is associated with disordered RhoA signalling, epithelial polarization and cytokinesis.

Hum Mol Genet 2012 Dec 10;21(24):5268-79. Epub 2012 Sep 10.

Department of Medical and Molecular Genetics, Centre for Rare Diseases and Personalized Medicine, School of Clinical and Experimental Medicine, University of Birmingham College of Medical and Dental Sciences, Edgbaston, Birmingham, UK.

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http://dx.doi.org/10.1093/hmg/dds378DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3755511PMC
December 2012

Downregulation of CASR expression and global loss of parafibromin staining are strong negative determinants of prognosis in parathyroid carcinoma.

Mod Pathol 2011 May 14;24(5):688-97. Epub 2011 Jan 14.

Department of Endocrinology and Metabolic Diseases, Leiden University Medical Center, Albinusdreef 2, Leiden, The Netherlands.

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http://www.nature.com/articles/modpathol2010236
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http://dx.doi.org/10.1038/modpathol.2010.236DOI Listing
May 2011

Comparative gene expression profiling analysis of urothelial carcinoma of the renal pelvis and bladder.

BMC Med Genomics 2010 Dec 15;3:58. Epub 2010 Dec 15.

Van Andel Research Institute, Grand Rapids, MI 49503, USA.

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http://dx.doi.org/10.1186/1755-8794-3-58DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3022544PMC
December 2010

Kinase targets in renal-cell carcinomas: reassessing the old and discovering the new.

Lancet Oncol 2010 Jun 8;11(6):571-8. Epub 2010 Apr 8.

Laboratory of Computational Biology, Van Andel Research Institute, Grand Rapids, MI, USA.

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http://dx.doi.org/10.1016/S1470-2045(09)70380-8DOI Listing
June 2010

The tumor suppressor parafibromin is required for posttranscriptional processing of histone mRNA.

Mol Carcinog 2010 Mar;49(3):215-23

Laboratory of Cancer Genetics, Van Andel Research Institute, Grand Rapids, Michigan 49503, USA.

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http://dx.doi.org/10.1002/mc.20591DOI Listing
March 2010

CDC73/HRPT2 CpG island hypermethylation and mutation of 5'-untranslated sequence are uncommon mechanisms of silencing parafibromin in parathyroid tumors.

Endocr Relat Cancer 2010 Mar 18;17(1):273-82. Epub 2010 Feb 18.

Hormones and Cancer Group, Kolling Institute of Medical Research, Royal North Shore Hospital, University of Sydney, E25, St Leonards, New South Wales 2065, Australia.

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http://dx.doi.org/10.1677/ERC-09-0291DOI Listing
March 2010

Maximizing RNA yield from archival renal tumors and optimizing gene expression analysis.

J Biomol Screen 2010 Jan 11;15(1):80-5. Epub 2009 Dec 11.

Department of Molecular and Cellular Biology, Roswell Park Cancer Institute, Buffalo, New York, USA.

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http://dx.doi.org/10.1177/1087057109355059DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2902272PMC
January 2010

Dual KS: Defining Gene Sets with Tissue Set Enrichment Analysis.

Cancer Inform 2010 Jan 21;9:1-9. Epub 2010 Jan 21.

These authors contributed equally to this work.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2816930PMC
January 2010

Regulation of endocytosis via the oxygen-sensing pathway.

Nat Med 2009 Mar 1;15(3):319-24. Epub 2009 Mar 1.

Department of Laboratory Medicine and Pathobiology, St. Michael's Hospital, University of Toronto, 1 King's College Circle, Toronto, Ontario M5S 1A8, Canada.

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http://dx.doi.org/10.1038/nm.1922DOI Listing
March 2009

Accuracy of combined protein gene product 9.5 and parafibromin markers for immunohistochemical diagnosis of parathyroid carcinoma.

J Clin Endocrinol Metab 2009 Feb 18;94(2):434-41. Epub 2008 Nov 18.

Kolling Institute of Medical Research, University of Sydney, Royal North Shore Hospital, St. Leonards, New South Wales 2065, Australia.

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http://dx.doi.org/10.1210/jc.2008-1740DOI Listing
February 2009

A comparison study reveals important features of agreement and disagreement between summarized DNA and RNA data obtained from renal cell carcinoma.

Mutat Res 2008 Nov 23;657(1):77-83. Epub 2008 Aug 23.

Laboratory of Cancer Genetics, Van Andel Research Institute, 333 Bostwick Avenue NE, Grand Rapids, MI 49503, USA.

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http://dx.doi.org/10.1016/j.mrgentox.2008.08.009DOI Listing
November 2008

Inhibition of Mxi1 suppresses HIF-2alpha-dependent renal cancer tumorigenesis.

Cancer Biol Ther 2008 Oct 3;7(10):1619-27. Epub 2008 Oct 3.

Department of Genitourinary Medical Oncology, MD Anderson Cancer Center, Houston, Texas 77030, USA.

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http://dx.doi.org/10.4161/cbt.7.10.6583DOI Listing
October 2008

The E2F3-Oncomir-1 axis is activated in Wilms' tumor.

Cancer Res 2008 Jun;68(11):4034-8

Laboratory of Molecular Epidemiology, Van Andel Research Institute, Grand Rapids, MI 49503, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-08-0592DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2442735PMC
June 2008

Familial hyperparathyroidism: surgical outcome after 30 years of follow-up in three families with germline HRPT2 mutations.

Surgery 2008 May 17;143(5):630-40. Epub 2008 Mar 17.

Department of Medicine, Surgery, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.

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http://dx.doi.org/10.1016/j.surg.2007.12.012DOI Listing
May 2008

Human kidney injury molecule-1 (hKIM-1): a useful immunohistochemical marker for diagnosing renal cell carcinoma and ovarian clear cell carcinoma.

Am J Surg Pathol 2007 Mar;31(3):371-81

Department of Laboratory Medicine, Geisinger Medical Center, 100 N. Academy Avenue, Danville, PA 17822, USA.

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http://dx.doi.org/10.1097/01.pas.0000213353.95508.67DOI Listing
March 2007

A tribute to George F. Vande Woude, a man of character: 2006 Scientific Symposium Winning the War against Cancer: from Genomics to Bedside and Back.

Cancer Res 2007 Mar 8;67(6):2394-5. Epub 2007 Mar 8.

Van Andel Research Institute, Grand Rapids, Michigan 49503, USA.

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http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
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http://dx.doi.org/10.1158/0008-5472.CAN-06-4304DOI Listing
March 2007

Renal papillary adenoma--a putative precursor of papillary renal cell carcinoma.

Hum Pathol 2007 Feb 23;38(2):239-46. Epub 2006 Oct 23.

Department of Pathology, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA.

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http://dx.doi.org/10.1016/j.humpath.2006.07.016DOI Listing
February 2007

Diagnostic value of cytokeratin 7 and parvalbumin in differentiating chromophobe renal cell carcinoma from renal oncocytoma.

Anal Quant Cytol Histol 2006 Aug;28(4):228-36

Department of Pathology, Northwestern University, Feinberg School of Medicine, Chicago, Illinois 60611, USA.

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August 2006

Expression of kidney-specific cadherin in chromophobe renal cell carcinoma and renal oncocytoma.

Am J Clin Pathol 2006 Jul;126(1):79-85

Department of Pathology, Northwestern University, Feinberg School of Medicine, Chicago, IL 60611, USA.

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http://dx.doi.org/10.1309/JFE2-B57Y-QFPW-PL10DOI Listing
July 2006

Elucidation of the molecular signatures of renal cell carcinoma by gene expression profiling.

J Med Invest 2006 Feb;53(1-2):9-19

Department of Urology, Institute of Health Biosciences, The University of Tokushima Graduate School, Japan.

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February 2006

Functional characterization of JMJD2A, a histone deacetylase- and retinoblastoma-binding protein.

J Biol Chem 2005 Aug 31;280(31):28507-18. Epub 2005 May 31.

Laboratory of Transcriptional and Immune Regulation, Brigham and Women's Hospital Laboratories, Cambridge, Massachusetts 02139, USA.

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http://dx.doi.org/10.1074/jbc.M413687200DOI Listing
August 2005

Spectral karyotyping of sarcomas and fibroblasts derived from Ink4a/Arf-deficient mice reveals chromosomal instability in vitro.

Int J Oncol 2005 Mar;26(3):629-34

Laboratory of Cell Signaling and Carcinogenesis, Van Andel Research Institute, Grand Rapids, MI 49503, USA.

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March 2005

Overexpression of glutathione s-transferase alpha in clear cell renal cell carcinoma.

Am J Clin Pathol 2005 Mar;123(3):421-9

Department of Pathology, Northwestern University, Feinberg School of Medicine, Chicago, IL 60611, USA.

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http://dx.doi.org/10.1309/AQXR-6B2Q-PUGD-638CDOI Listing
March 2005

Gene expression profiling of renal cell carcinoma and clinical implications.

Urology 2005 Feb;65(2):231-7

Brady Urological Institute, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S009042950400978
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http://dx.doi.org/10.1016/j.urology.2004.08.038DOI Listing
February 2005

Coexpression of erythropoietin and erythropoietin receptor in von Hippel-Lindau disease-associated renal cysts and renal cell carcinoma.

Clin Cancer Res 2005 Feb;11(3):1059-64

Surgical Neurology Branch, National Institute of Neurological Disorders and Stroke, National Cancer Institute/NIH, 10 Center Drive, Bethesda, MD 20892, USA.

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February 2005

Expression of RON Proto-oncogene in Renal Oncocytoma and Chromophobe Renal Cell Carcinoma.

Am J Surg Pathol 2004 Aug;28(8):1045-50

Department of Pathology, Northwestern University, Feinberg School of Medicine, 251 East Huron Street, Chicago, IL 60611, USA.

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http://dx.doi.org/10.1097/01.pas.0000128661.58697.7dDOI Listing
August 2004

HRPT2 and parathyroid cancer.

Lancet Oncol 2004 Feb;5(2):78

Kolling Institute of Medical Research, Royal North Shore Hospital, Sydney, NSW, Australia.

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http://dx.doi.org/10.1016/S1470-2045(04)01379-8DOI Listing
February 2004

Gene expression profiling of renal cell carcinoma and its implications in diagnosis, prognosis, and therapeutics.

Adv Cancer Res 2003 ;89:157-81

Laboratory of Cancer Genetics, Van Andel Research Institute, Grand Rapids, Michigan 49503, USA.

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December 2003