Biju Bhargavan

Biju Bhargavan

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Biju Bhargavan

Biju Bhargavan

Publications by authors named "Biju Bhargavan"

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19Publications

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Epigenetics, N-myrystoyltransferase-1 and casein kinase-2-alpha modulates the increased replication of HIV-1 CRF02_AG, compared to subtype-B viruses.

Sci Rep 2019 07 23;9(1):10689. Epub 2019 Jul 23.

Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, Omaha, Nebraska, 68198-5800, USA.

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http://dx.doi.org/10.1038/s41598-019-47069-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6650493PMC
July 2019

Toll-Like Receptor-3 Mediates HIV-1-Induced Interleukin-6 Expression in the Human Brain Endothelium via TAK1 and JNK Pathways: Implications for Viral Neuropathogenesis.

Mol Neurobiol 2018 Jul 11;55(7):5976-5992. Epub 2017 Nov 11.

Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, Omaha, NE, 68198-5800, USA.

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http://dx.doi.org/10.1007/s12035-017-0816-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6226278PMC
July 2018

Differential Mechanisms of Inflammation and Endothelial Dysfunction by HIV-1 Subtype-B and Recombinant CRF02_AG Tat Proteins on Human Brain Microvascular Endothelial Cells: Implications for Viral Neuropathogenesis.

Mol Neurobiol 2018 02 27;55(2):1352-1363. Epub 2017 Jan 27.

Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, Omaha, NE, 68198-5800, USA.

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http://link.springer.com/10.1007/s12035-017-0382-0
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http://dx.doi.org/10.1007/s12035-017-0382-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6507400PMC
February 2018

Creation of a long-acting nanoformulated dolutegravir.

Nat Commun 2018 02 6;9(1):443. Epub 2018 Feb 6.

Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, Omaha, NE, 68198, USA.

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http://dx.doi.org/10.1038/s41467-018-02885-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5799307PMC
February 2018

Toll-like receptor-3 mediates HIV-1 transactivation via NFκB and JNK pathways and histone acetylation, but prolonged activation suppresses Tat and HIV-1 replication.

Cell Signal 2016 Feb 11;28(2):7-22. Epub 2015 Nov 11.

Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, Omaha, NE 68198-5800, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cellsig.2015.11.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4890564PMC
February 2016

Differential effects of Tat proteins derived from HIV-1 subtypes B and recombinant CRF02_AG on human brain microvascular endothelial cells: implications for blood-brain barrier dysfunction.

J Cereb Blood Flow Metab 2014 Jun 26;34(6):1047-59. Epub 2014 Mar 26.

Department of Pharmacology and Experimental Neuroscience, University of Nebraska Medical Center, Omaha, Nebraska, USA.

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http://dx.doi.org/10.1038/jcbfm.2014.54DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4050250PMC
June 2014

Epigenetic repression of LEDGF during UVB exposure by recruitment of SUV39H1 and HDAC1 to the Sp1-responsive elements within LEDGF promoter CpG island.

Epigenetics 2013 Mar 5;8(3):268-80. Epub 2013 Feb 5.

Department of Ophthalmology and Visual Sciences, University of Nebraska Medical Center, Omaha, NE, USA.

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http://dx.doi.org/10.4161/epi.23861DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3669119PMC
March 2013

Transcriptional protein Sp1 regulates LEDGF transcription by directly interacting with its cis-elements in GC-rich region of TATA-less gene promoter.

PLoS One 2012 16;7(5):e37012. Epub 2012 May 16.

Department of Ophthalmology and Visual Sciences, University of Nebraska Medical Center, Omaha, Nebraska, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0037012PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3353957PMC
January 2013

Deficiency of Prdx6 in lens epithelial cells induces ER stress response-mediated impaired homeostasis and apoptosis.

Am J Physiol Cell Physiol 2011 Oct 15;301(4):C954-67. Epub 2011 Jun 15.

Dept. of Ophthalmology and Visual Sciences, Univ. of Nebraska Medical Center, Omaha, 68198-5840, USA.

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http://dx.doi.org/10.1152/ajpcell.00061.2011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3191562PMC
October 2011

Medicarpin inhibits osteoclastogenesis and has nonestrogenic bone conserving effect in ovariectomized mice.

Mol Cell Endocrinol 2010 Aug 4;325(1-2):101-9. Epub 2010 Jun 4.

Division of Endocrinology, Central Drug Research Institute (Council of Scientific and Industrial Research), Chattar Manzil, P.O. Box 173, Lucknow, India.

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http://dx.doi.org/10.1016/j.mce.2010.05.016DOI Listing
August 2010

Osteogenic activity of constituents from Butea monosperma.

Bioorg Med Chem Lett 2009 Feb 24;19(3):610-3. Epub 2008 Dec 24.

Medicinal and Process Chemistry Division, Central Drug Research Institute, Chattar MAnzil Palace, M. G. Marg, Lucknow 226 001, Uttar Pradesh, India.

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http://dx.doi.org/10.1016/j.bmcl.2008.12.064DOI Listing
February 2009

Pregnancy interceptive activity of the roots of Calotropis gigantea Linn. in rats.

Contraception 2007 Apr 19;75(4):318-22. Epub 2007 Jan 19.

Division of Endocrinology, Central Drug Research Institute, Lucknow 226-001, India.

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http://dx.doi.org/10.1016/j.contraception.2006.11.010DOI Listing
April 2007