Bianca Sparatore

Bianca Sparatore

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Bianca Sparatore

Bianca Sparatore

Publications by authors named "Bianca Sparatore"

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A new human calpastatin skipped of the inhibitory region protects calpain-1 from inactivation and degradation.

Biochim Biophys Acta Mol Cell Res 2019 Aug 5;1866(8):1260-1271. Epub 2019 Apr 5.

Department of Experimental Medicine (DIMES), Biochemistry Section, University of Genova, Viale Benedetto XV, 1-16132 Genova, Italy; Centre of Excellence for Biomedical Research (CEBR), University of Genova, Viale Benedetto XV, 7-16132 Genova, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.bbamcr.2019.04.005DOI Listing
August 2019

Unexpected role of the L-domain of calpastatin during the autoproteolytic activation of human erythrocyte calpain.

Biosci Rep 2018 04 20;38(2). Epub 2018 Apr 20.

Department of Experimental Medicine (DIMES), Biochemistry Section, University of Genova, Viale Benedetto XV-1, 16132 Genova, Italy.

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http://dx.doi.org/10.1042/BSR20180147DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5968184PMC
April 2018

Abnormal activation of calpain and protein kinase Cα promotes a constitutive release of matrix metalloproteinase 9 in peripheral blood mononuclear cells from cystic fibrosis patients.

Arch Biochem Biophys 2016 08 25;604:103-12. Epub 2016 Jun 25.

Department of Experimental Medicine (DIMES) - Biochemistry Section, Viale Benedetto XV, 1, 16132, Genova, Italy; Center of Excellence for Biomedical Research (CEBR), University of Genova, Viale Benedetto XV, 1, 16132, Genova, Italy.

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http://dx.doi.org/10.1016/j.abb.2016.06.015DOI Listing
August 2016

Differential regulation of the calpain-calpastatin complex by the L-domain of calpastatin.

Biochim Biophys Acta 2014 Nov 12;1843(11):2583-91. Epub 2014 Jul 12.

Department of Experimental Medicine (DIMES), Biochemistry Section, University of Genova, Viale Benedetto XV, 1-16132 Genova, Italy; Centre of Excellence for Biomedical Research, University of Genova, Viale Benedetto XV, 7-16132 Genova, Italy.

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http://dx.doi.org/10.1016/j.bbamcr.2014.07.002DOI Listing
November 2014

18β-glycyrrhetic acid inhibits immune activation triggered by HMGB1, a pro-inflammatory protein found in the tear fluid during conjunctivitis and blepharitis.

Ocul Immunol Inflamm 2011 Jun 22;19(3):180-5. Epub 2011 Mar 22.

Department of Preclinical and Clinical Pharmacology, University of Florence, Florence, Italy.

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http://dx.doi.org/10.3109/09273948.2010.538121DOI Listing
June 2011

Calpain digestion and HSP90-based chaperone protection modulate the level of plasma membrane F508del-CFTR.

Biochim Biophys Acta 2011 Jan 24;1813(1):50-9. Epub 2010 Nov 24.

Department of Experimental Medicine, University of Genoa, Genoa, Italy.

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http://dx.doi.org/10.1016/j.bbamcr.2010.11.008DOI Listing
January 2011

Functional role of the charge at the T538 residue in the control of protein kinase Ctheta.

Arch Biochem Biophys 2009 Jan 21;481(2):202-9. Epub 2008 Nov 21.

Department of Experimental Medicine-Biochemistry Section, Centre of Excellence for Biomedical Research, University of Genoa, Viale Benedetto XV, 1-16132 Genoa, Italy.

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http://linkinghub.elsevier.com/retrieve/pii/S000398610800531
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http://dx.doi.org/10.1016/j.abb.2008.11.013DOI Listing
January 2009

Selective proinflammatory activation of astrocytes by high-mobility group box 1 protein signaling.

J Immunol 2007 Dec;179(12):8525-32

Department of Experimental Medicine-Biochemistry Section and Centre of Excellence for Biomedical Research, University of Genoa, Viale Benedetto XV, Genoa, Italy.

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http://dx.doi.org/10.4049/jimmunol.179.12.8525DOI Listing
December 2007

Stimulation of excitatory amino acid release from adult mouse brain glia subcellular particles by high mobility group box 1 protein.

J Neurochem 2006 Nov 14;99(3):827-38. Epub 2006 Aug 14.

Department of Experimental Medicine and Center of Excellence for Biomedical Research, University of Genoa, Genoa, Italy.

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http://dx.doi.org/10.1111/j.1471-4159.2006.04120.xDOI Listing
November 2006

Cutting edge: extracellular high mobility group box-1 protein is a proangiogenic cytokine.

J Immunol 2006 Jan;176(1):12-5

Unit of General Pathology and Immunology, Department of Biomedical Sciences and Biotechnology, University of Brecia, Brescia, Italy.

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http://dx.doi.org/10.4049/jimmunol.176.1.12DOI Listing
January 2006

Activation of A431 human carcinoma cell motility by extracellular high-mobility group box 1 protein and epidermal growth factor stimuli.

Biochem J 2005 Jul;389(Pt 1):215-21

Department of Experimental Medicine, Biochemistry Section and Centre of Excellence for Biomedical Research, University of Genoa, Viale Benedetto XV, 1-16132 Genoa, Italy.

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http://www.biochemj.org/content/ppbiochemj/389/1/215.full.pd
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http://biochemj.org/lookup/doi/10.1042/BJ20050053
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http://dx.doi.org/10.1042/BJ20050053DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1184554PMC
July 2005

Role of the kinase activation loop on protein kinase C theta activity and intracellular localisation.

FEBS Lett 2003 Nov;554(1-2):35-40

Department of Experimental Medicine, Biochemistry Section, University of Genoa, Viale Benedetto XV, 16132 Genoa, Italy.

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http://dx.doi.org/10.1016/s0014-5793(03)01073-1DOI Listing
November 2003