Bianca J J M Brundel

Bianca J J M Brundel

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Bianca J J M Brundel

Bianca J J M Brundel

Publications by authors named "Bianca J J M Brundel"

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Heat shock protein inducer GGA*-59 reverses contractile and structural remodeling via restoration of the microtubule network in experimental Atrial Fibrillation.

J Mol Cell Cardiol 2019 Sep 11;134:86-97. Epub 2019 Jul 11.

Department of Physiology, Amsterdam UMC, Vrije Universiteit Amsterdam, Physiology, Amsterdam Cardiovascular Sciences, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.yjmcc.2019.07.006DOI Listing
September 2019

Oral geranylgeranylacetone treatment increases heat shock protein expression in human atrial tissue.

Heart Rhythm 2019 Jul 12. Epub 2019 Jul 12.

Department of Physiology, Amsterdam UMC, Vrije Universiteit, Amsterdam Cardiovascular Sciences, Amsterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.hrthm.2019.07.010DOI Listing
July 2019

Protein Quality Control Activation and Microtubule Remodeling in Hypertrophic Cardiomyopathy.

Cells 2019 07 18;8(7). Epub 2019 Jul 18.

Department of Physiology, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam Cardiovascular Sciences, 1081 HV Amsterdam, The Netherlands.

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http://dx.doi.org/10.3390/cells8070741DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6678711PMC
July 2019

Untying the knot: protein quality control in inherited cardiomyopathies.

Pflugers Arch 2019 May 14;471(5):795-806. Epub 2018 Aug 14.

Amsterdam UMC, Department of Physiology, Vrije Universiteit Amsterdam, Amsterdam Cardiovascular Sciences, O2 building 11W53, De Boelelaan 1117, 1081HV, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/s00424-018-2194-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6475634PMC
May 2019

Role of HDACs in cardiac electropathology: Therapeutic implications for atrial fibrillation.

Biochim Biophys Acta Mol Cell Res 2019 Mar 14. Epub 2019 Mar 14.

Department of Physiology, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam Cardiovascular Sciences, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.bbamcr.2019.03.006DOI Listing
March 2019

Converse role of class I and class IIa HDACs in the progression of atrial fibrillation.

J Mol Cell Cardiol 2018 Dec 12;125:39-49. Epub 2018 Oct 12.

Department of Physiology, Amsterdam UMC, Amsterdam Cardiovascular Sciences, Vrije Universiteit Amsterdam, the Netherlands. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00222828183054
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http://dx.doi.org/10.1016/j.yjmcc.2018.09.010DOI Listing
December 2018

Role of Autophagy in Proteostasis: Friend and Foe in Cardiac Diseases.

Cells 2018 Dec 19;7(12). Epub 2018 Dec 19.

Department of Physiology, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam Cardiovascular Sciences, 1081 HV Amsterdam, The Netherlands.

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http://dx.doi.org/10.3390/cells7120279DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316637PMC
December 2018

Application of kinomic array analysis to screen for altered kinases in atrial fibrillation remodeling.

Heart Rhythm 2018 11 11;15(11):1708-1716. Epub 2018 Jun 11.

Department of Clinical Pharmacy and Pharmacology, Groningen University Institute for Drug Exploration (GUIDE), University of Groningen, University Medical Center Groningen, Groningen, The Netherlands; Department of Physiology, Amsterdam Cardiovascular Sciences, VU University Medical Center, Amsterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.hrthm.2018.06.014DOI Listing
November 2018

Torpor-arousal cycles in Syrian hamster heart are associated with transient activation of the protein quality control system.

Comp Biochem Physiol B Biochem Mol Biol 2018 09 9;223:23-28. Epub 2018 Jun 9.

Department of Clinical Pharmacy and Pharmacology, University of Groningen, University Medical Center Groningen, The Netherlands.

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http://dx.doi.org/10.1016/j.cbpb.2018.06.001DOI Listing
September 2018

Spatial distribution of conduction disorders during sinus rhythm.

Int J Cardiol 2017 Dec 2;249:220-225. Epub 2017 Sep 2.

Department of Cardiology, Erasmus MC, 's Gravendijkwal 230, 3015 CE, Rotterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.ijcard.2017.08.067DOI Listing
December 2017

Proteostasis in cardiac health and disease.

Nat Rev Cardiol 2017 Nov 29;14(11):637-653. Epub 2017 Jun 29.

Department of Physiology, Amsterdam Cardiovascular Sciences, VU University Medical Center, De Boelelaan 1117, 1081 HZ Amsterdam, The Netherlands.

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http://dx.doi.org/10.1038/nrcardio.2017.89DOI Listing
November 2017

Erratum: Genetic loci associated with heart rate variability and their effects on cardiac disease risk.

Authors:
Ilja M Nolte M Loretto Munoz Vinicius Tragante Azmeraw T Amare Rick Jansen Ahmad Vaez Benedikt von der Heyde Christy L Avery Joshua C Bis Bram Dierckx Jenny van Dongen Stephanie M Gogarten Philippe Goyette Jussi Hernesniemi Ville Huikari Shih-Jen Hwang Deepali Jaju Kathleen F Kerr Alexander Kluttig Bouwe P Krijthe Jitender Kumar Sander W van der Laan Leo-Pekka Lyytikäinen Adam X Maihofer Arpi Minassian Peter J van der Most Martina Müller-Nurasyid Michel Nivard Erika Salvi James D Stewart Julian F Thayer Niek Verweij Andrew Wong Delilah Zabaneh Mohammad H Zafarmand Abdel Abdellaoui Sulayma Albarwani Christine Albert Alvaro Alonso Foram Ashar Juha Auvinen Tomas Axelsson Dewleen G Baker Paul I W de Bakker Matteo Barcella Riad Bayoumi Rob J Bieringa Dorret Boomsma Gabrielle Boucher Annie R Britton Ingrid Christophersen Andrea Dietrich George B Ehret Patrick T Ellinor Markku Eskola Janine F Felix John S Floras Oscar H Franco Peter Friberg Maaike G J Gademan Mark A Geyer Vilmantas Giedraitis Catharina A Hartman Daiane Hemerich Albert Hofman Jouke-Jan Hottenga Heikki Huikuri Nina Hutri-Kähönen Xavier Jouven Juhani Junttila Markus Juonala Antti M Kiviniemi Jan A Kors Meena Kumari Tatiana Kuznetsova Cathy C Laurie Joop D Lefrandt Yong Li Yun Li Duanping Liao Marian C Limacher Henry J Lin Cecilia M Lindgren Steven A Lubitz Anubha Mahajan Barbara McKnight Henriette Meyer Zu Schwabedissen Yuri Milaneschi Nina Mononen Andrew P Morris Mike A Nalls Gerjan Navis Melanie Neijts Kjell Nikus Kari E North Daniel T O'Connor Johan Ormel Siegfried Perz Annette Peters Bruce M Psaty Olli T Raitakari Victoria B Risbrough Moritz F Sinner David Siscovick Johannes H Smit Nicholas L Smith Elsayed Z Soliman Nona Sotoodehnia Jan A Staessen Phyllis K Stein Adrienne M Stilp Katarzyna Stolarz-Skrzypek Konstantin Strauch Johan Sundström Cees A Swenne Ann-Christine Syvänen Jean-Claude Tardif Kent D Taylor Alexander Teumer Timothy A Thornton Lesley E Tinker André G Uitterlinden Jessica van Setten Andreas Voss Melanie Waldenberger Kirk C Wilhelmsen Gonneke Willemsen Quenna Wong Zhu-Ming Zhang Alan B Zonderman Daniele Cusi Michele K Evans Halina K Greiser Pim van der Harst Mohammad Hassan Erik Ingelsson Marjo-Riitta Järvelin Stefan Kääb Mika Kähönen Mika Kivimaki Charles Kooperberg Diana Kuh Terho Lehtimäki Lars Lind Caroline M Nievergelt Chris J O'Donnell Albertine J Oldehinkel Brenda Penninx Alexander P Reiner Harriëtte Riese Arie M van Roon John D Rioux Jerome I Rotter Tamar Sofer Bruno H Stricker Henning Tiemeier Tanja G M Vrijkotte Folkert W Asselbergs Bianca J J M Brundel Susan R Heckbert Eric A Whitsel Marcel den Hoed Harold Snieder Eco J C de Geus

Nat Commun 2017 08 2;8:16140. Epub 2017 Aug 2.

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http://dx.doi.org/10.1038/ncomms16140DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5543301PMC
August 2017

The protective role of small heat shock proteins in cardiac diseases: key role in atrial fibrillation.

Cell Stress Chaperones 2017 07 8;22(4):665-674. Epub 2017 May 8.

Department of Physiology, Institute for Cardiovascular Research, VU University Medical Center, De Boelelaan 1117, 1081 HV, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/s12192-017-0799-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5465041PMC
July 2017

Genetic loci associated with heart rate variability and their effects on cardiac disease risk.

Authors:
Ilja M Nolte M Loretto Munoz Vinicius Tragante Azmeraw T Amare Rick Jansen Ahmad Vaez Benedikt von der Heyde Christy L Avery Joshua C Bis Bram Dierckx Jenny van Dongen Stephanie M Gogarten Philippe Goyette Jussi Hernesniemi Ville Huikari Shih-Jen Hwang Deepali Jaju Kathleen F Kerr Alexander Kluttig Bouwe P Krijthe Jitender Kumar Sander W van der Laan Leo-Pekka Lyytikäinen Adam X Maihofer Arpi Minassian Peter J van der Most Martina Müller-Nurasyid Michel Nivard Erika Salvi James D Stewart Julian F Thayer Niek Verweij Andrew Wong Delilah Zabaneh Mohammad H Zafarmand Abdel Abdellaoui Sulayma Albarwani Christine Albert Alvaro Alonso Foram Ashar Juha Auvinen Tomas Axelsson Dewleen G Baker Paul I W de Bakker Matteo Barcella Riad Bayoumi Rob J Bieringa Dorret Boomsma Gabrielle Boucher Annie R Britton Ingrid Christophersen Andrea Dietrich George B Ehret Patrick T Ellinor Markku Eskola Janine F Felix John S Floras Oscar H Franco Peter Friberg Maaike G J Gademan Mark A Geyer Vilmantas Giedraitis Catharina A Hartman Daiane Hemerich Albert Hofman Jouke-Jan Hottenga Heikki Huikuri Nina Hutri-Kähönen Xavier Jouven Juhani Junttila Markus Juonala Antti M Kiviniemi Jan A Kors Meena Kumari Tatiana Kuznetsova Cathy C Laurie Joop D Lefrandt Yong Li Yun Li Duanping Liao Marian C Limacher Henry J Lin Cecilia M Lindgren Steven A Lubitz Anubha Mahajan Barbara McKnight Henriette Meyer Zu Schwabedissen Yuri Milaneschi Nina Mononen Andrew P Morris Mike A Nalls Gerjan Navis Melanie Neijts Kjell Nikus Kari E North Daniel T O'Connor Johan Ormel Siegfried Perz Annette Peters Bruce M Psaty Olli T Raitakari Victoria B Risbrough Moritz F Sinner David Siscovick Johannes H Smit Nicholas L Smith Elsayed Z Soliman Nona Sotoodehnia Jan A Staessen Phyllis K Stein Adrienne M Stilp Katarzyna Stolarz-Skrzypek Konstantin Strauch Johan Sundström Cees A Swenne Ann-Christine Syvänen Jean-Claude Tardif Kent D Taylor Alexander Teumer Timothy A Thornton Lesley E Tinker André G Uitterlinden Jessica van Setten Andreas Voss Melanie Waldenberger Kirk C Wilhelmsen Gonneke Willemsen Quenna Wong Zhu-Ming Zhang Alan B Zonderman Daniele Cusi Michele K Evans Halina K Greiser Pim van der Harst Mohammad Hassan Erik Ingelsson Marjo-Riitta Järvelin Stefan Kääb Mika Kähönen Mika Kivimaki Charles Kooperberg Diana Kuh Terho Lehtimäki Lars Lind Caroline M Nievergelt Chris J O'Donnell Albertine J Oldehinkel Brenda Penninx Alexander P Reiner Harriëtte Riese Arie M van Roon John D Rioux Jerome I Rotter Tamar Sofer Bruno H Stricker Henning Tiemeier Tanja G M Vrijkotte Folkert W Asselbergs Bianca J J M Brundel Susan R Heckbert Eric A Whitsel Marcel den Hoed Harold Snieder Eco J C de Geus

Nat Commun 2017 06 14;8:15805. Epub 2017 Jun 14.

Department of Biological Psychology, Behavioral and Movement Sciences, VU University, Amsterdam 1081 BT, The Netherlands.

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http://dx.doi.org/10.1038/ncomms15805DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5474732PMC
June 2017

Derailed Proteostasis as a Determinant of Cardiac Aging.

Can J Cardiol 2016 09 19;32(9):1166.e11-20. Epub 2016 Mar 19.

Department of Clinical Pharmacy and Pharmacology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands; Department of Physiology, Institute for Cardiovascular Research, VU University Medical Center, Amsterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.cjca.2016.03.005DOI Listing
September 2016

RhoA Activation Sensitizes Cells to Proteotoxic Stimuli by Abrogating the HSF1-Dependent Heat Shock Response.

PLoS One 2015 20;10(7):e0133553. Epub 2015 Jul 20.

Department of Clinical Pharmacy and Pharmacology, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands; Department of Physiology, Institute for Cardiovascular Research, VU University Medical Center, Amsterdam, The Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0133553PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4508109PMC
April 2016

Keeping up the balance: role of HDACs in cardiac proteostasis and therapeutic implications for atrial fibrillation.

Cardiovasc Res 2016 Apr 8;109(4):519-26. Epub 2015 Dec 8.

Department of Clinical Pharmacy and Pharmacology, University Medical Centre Groningen, University of Groningen, Hanzeplein 1, PO Box 30 001, 9700RB Groningen, The Netherlands Department of Physiology, Institute for Cardiovascular Research, VU University Medical Center, Amsterdam, The Netherlands

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http://dx.doi.org/10.1093/cvr/cvv265DOI Listing
April 2016

Time Course of Atrial Fibrillation in Patients With Congenital Heart Defects.

Circ Arrhythm Electrophysiol 2015 Oct 14;8(5):1065-72. Epub 2015 Aug 14.

From the Department of Cardiology (C.P.T., T.T.T.K.R., C.H., A.Y., L.J.J., M.W., J.W.R.-H., N.M.S.d.G.) and Department of Cardio-Thoracic Surgery (A.J.J.C.B.), Erasmus University Medical Center, Rotterdam, The Netherlands; Department of Cardiology, Haga Hospital, The Hague, The Netherlands (M.G., J.W.J.V.); Department of Clinical Pharmacy and Pharmacology, University Medical Center Groningen, Groningen, The Netherlands (B.J.J.M.B.); Department of Cardiology, VU University Medical Center, Amsterdam, The Netherlands (B.J.J.M.B., T.C.K.); Department of Cardiology, Radboud University Medical Center, Nijmegen; The Netherlands (R.E.); Department of Cardiology, Amphia Hospital, Breda, The Netherlands (S.G.M.); Department of Cardiology; Medisch Spectrum Twente, Enschede, The Netherlands (H.G.R.D., J.M.v.O.); Department of Cardiology, Catharina Hospital, Eindhoven, The Netherlands (P.v.d.V.); Cardiology, Inselspital, University of Bern, Bern, Switzerland (E.D.); Department of Cardiology, Boston Children's Hospital, MA (J.K.T.); and Department of Pediatrics, Harvard Medical School, Boston, MA (J.K.T.).

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http://dx.doi.org/10.1161/CIRCEP.115.003272DOI Listing
October 2015

Reviving the protein quality control system: therapeutic target for cardiac disease in the elderly.

Trends Cardiovasc Med 2015 Apr 28;25(3):243-7. Epub 2014 Oct 28.

Department of Clinical Pharmacy and Pharmacology, EB71, University Institute for Drug Exploration (GUIDE), University Medical Center Groningen, University of Groningen, Groningen, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.tcm.2014.10.013DOI Listing
April 2015

Activation of histone deacetylase-6 induces contractile dysfunction through derailment of α-tubulin proteostasis in experimental and human atrial fibrillation.

Circulation 2014 Jan 21;129(3):346-58. Epub 2013 Oct 21.

Departments of Clinical Pharmacology (D.Z., R.A.M.M., F.H.-B., R.H.H., B.J.J.M.B.) and Cell Biology (O.C.M.S.), University Medical Center Groningen, University of Groningen, Groningen, The Netherlands; Research Center and Department of Medicine, Montreal Heart Institute and Université de Montréal, Montreal, QB, Canada (C.T.W., X.Y.Q., A.T., S.N.); Chang-Gung Memorial Hospital and Chang-Gung University, Taoyuan, Taiwan, Republic of China (C.T.W.); Nyken BV, Groningen, The Netherlands (F.-H.B.); Ankara University Biotechnology Institute, Ankara, Turkey (G.C.D., S.D.); Ankara University Stem Cell Institute, Ankara, Turkey (G.C.D., S.D., A.R.A.); Department of Cardiovascular Surgery, Ankara University School of Medicine, Ankara, Turkey (S.D., A.R.A.); and Department of Pharmacology, McGill University, Montreal, QB, Canada (S.N.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.113.005300DOI Listing
January 2014

Role of small-conductance calcium-activated potassium channels in atrial electrophysiology and fibrillation in the dog.

Circulation 2014 Jan 4;129(4):430-40. Epub 2013 Nov 4.

Research Center (X.-Y.Q., P.N., C.-T.W., H.H., M.H., M.A., S.N.), Montreal Heart Institute, Université de Montréal, Montreal, Quebec, Canada; Cardiac and Circulatory Research Section (J.G.D., M.G.), Faculty of Health Sciences, University of Copenhagen and Acesion Pharma, Copenhagen, Denmark; Department of Clinical Pharmacology (B.J.J.M.B.), University of Groningen, University Medical Center Groningen, Groningen, The Netherlands; Division of Experimental Cardiology (X.-B.Z., D.D.), Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany; Chang-Gung Memorial Hospital and University Taoyuan (C.-T.W.), Taoyuan, Taiwan, China; Institute of Pharmacology (D.D.), Faculty of Medicine, University Duisburg-Essen, Essen, Germany.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.113.003019DOI Listing
January 2014

Identification of heart rate-associated loci and their effects on cardiac conduction and rhythm disorders.

Authors:
Marcel den Hoed Mark Eijgelsheim Tõnu Esko Bianca J J M Brundel David S Peal David M Evans Ilja M Nolte Ayellet V Segrè Hilma Holm Robert E Handsaker Harm-Jan Westra Toby Johnson Aaron Isaacs Jian Yang Alicia Lundby Jing Hua Zhao Young Jin Kim Min Jin Go Peter Almgren Murielle Bochud Gabrielle Boucher Marilyn C Cornelis Daniel Gudbjartsson David Hadley Pim van der Harst Caroline Hayward Martin den Heijer Wilmar Igl Anne U Jackson Zoltán Kutalik Jian'an Luan John P Kemp Kati Kristiansson Claes Ladenvall Mattias Lorentzon May E Montasser Omer T Njajou Paul F O'Reilly Sandosh Padmanabhan Beate St Pourcain Tuomo Rankinen Perttu Salo Toshiko Tanaka Nicholas J Timpson Veronique Vitart Lindsay Waite William Wheeler Weihua Zhang Harmen H M Draisma Mary F Feitosa Kathleen F Kerr Penelope A Lind Evelin Mihailov N Charlotte Onland-Moret Ci Song Michael N Weedon Weijia Xie Loic Yengo Devin Absher Christine M Albert Alvaro Alonso Dan E Arking Paul I W de Bakker Beverley Balkau Cristina Barlassina Paola Benaglio Joshua C Bis Nabila Bouatia-Naji Søren Brage Stephen J Chanock Peter S Chines Mina Chung Dawood Darbar Christian Dina Marcus Dörr Paul Elliott Stephan B Felix Krista Fischer Christian Fuchsberger Eco J C de Geus Philippe Goyette Vilmundur Gudnason Tamara B Harris Anna-Liisa Hartikainen Aki S Havulinna Susan R Heckbert Andrew A Hicks Albert Hofman Suzanne Holewijn Femke Hoogstra-Berends Jouke-Jan Hottenga Majken K Jensen Asa Johansson Juhani Junttila Stefan Kääb Bart Kanon Shamika Ketkar Kay-Tee Khaw Joshua W Knowles Angrad S Kooner Jan A Kors Meena Kumari Lili Milani Päivi Laiho Edward G Lakatta Claudia Langenberg Maarten Leusink Yongmei Liu Robert N Luben Kathryn L Lunetta Stacey N Lynch Marcello R P Markus Pedro Marques-Vidal Irene Mateo Leach Wendy L McArdle Steven A McCarroll Sarah E Medland Kathryn A Miller Grant W Montgomery Alanna C Morrison Martina Müller-Nurasyid Pau Navarro Mari Nelis Jeffrey R O'Connell Christopher J O'Donnell Ken K Ong Anne B Newman Annette Peters Ozren Polasek Anneli Pouta Peter P Pramstaller Bruce M Psaty Dabeeru C Rao Susan M Ring Elizabeth J Rossin Diana Rudan Serena Sanna Robert A Scott Jaban S Sehmi Stephen Sharp Jordan T Shin Andrew B Singleton Albert V Smith Nicole Soranzo Tim D Spector Chip Stewart Heather M Stringham Kirill V Tarasov André G Uitterlinden Liesbeth Vandenput Shih-Jen Hwang John B Whitfield Cisca Wijmenga Sarah H Wild Gonneke Willemsen James F Wilson Jacqueline C M Witteman Andrew Wong Quenna Wong Yalda Jamshidi Paavo Zitting Jolanda M A Boer Dorret I Boomsma Ingrid B Borecki Cornelia M van Duijn Ulf Ekelund Nita G Forouhi Philippe Froguel Aroon Hingorani Erik Ingelsson Mika Kivimaki Richard A Kronmal Diana Kuh Lars Lind Nicholas G Martin Ben A Oostra Nancy L Pedersen Thomas Quertermous Jerome I Rotter Yvonne T van der Schouw W M Monique Verschuren Mark Walker Demetrius Albanes David O Arnar Themistocles L Assimes Stefania Bandinelli Michael Boehnke Rudolf A de Boer Claude Bouchard W L Mark Caulfield John C Chambers Gary Curhan Daniele Cusi Johan Eriksson Luigi Ferrucci Wiek H van Gilst Nicola Glorioso Jacqueline de Graaf Leif Groop Ulf Gyllensten Wen-Chi Hsueh Frank B Hu Heikki V Huikuri David J Hunter Carlos Iribarren Bo Isomaa Marjo-Riitta Jarvelin Antti Jula Mika Kähönen Lambertus A Kiemeney Melanie M van der Klauw Jaspal S Kooner Peter Kraft Licia Iacoviello Terho Lehtimäki Marja-Liisa L Lokki Braxton D Mitchell Gerjan Navis Markku S Nieminen Claes Ohlsson Neil R Poulter Lu Qi Olli T Raitakari Eric B Rimm John D Rioux Federica Rizzi Igor Rudan Veikko Salomaa Peter S Sever Denis C Shields Alan R Shuldiner Juha Sinisalo Alice V Stanton Ronald P Stolk David P Strachan Jean-Claude Tardif Unnur Thorsteinsdottir Jaako Tuomilehto Dirk J van Veldhuisen Jarmo Virtamo Jorma Viikari Peter Vollenweider Gérard Waeber Elisabeth Widen Yoon Shin Cho Jesper V Olsen Peter M Visscher Cristen Willer Lude Franke Jeanette Erdmann John R Thompson Arne Pfeufer Nona Sotoodehnia Christopher Newton-Cheh Patrick T Ellinor Bruno H Ch Stricker Andres Metspalu Markus Perola Jacques S Beckmann George Davey Smith Kari Stefansson Nicholas J Wareham Patricia B Munroe Ody C M Sibon David J Milan Harold Snieder Nilesh J Samani Ruth J F Loos

Nat Genet 2013 Jun 14;45(6):621-31. Epub 2013 Apr 14.

Medical Research Council MRC Epidemiology Unit, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK.

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http://www.nature.com/doifinder/10.1038/ng.2610
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http://dx.doi.org/10.1038/ng.2610DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3696959PMC
June 2013

Loss of proteostatic control as a substrate for atrial fibrillation: a novel target for upstream therapy by heat shock proteins.

Front Physiol 2012 23;3:36. Epub 2012 Feb 23.

Department of Clinical Pharmacology, Groningen University Institute for Drug Exploration, University Medical Center Groningen, University of Groningen Groningen, Netherlands.

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http://dx.doi.org/10.3389/fphys.2012.00036DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3284689PMC
October 2012

Heat shock protein-inducing compounds as therapeutics to restore proteostasis in atrial fibrillation.

Trends Cardiovasc Med 2012 Apr 3;22(3):62-8. Epub 2012 Aug 3.

Department of Clinical Pharmacology, University of Groningen, University Medical Center Groningen, 9713 AV Groningen, The Netherlands.

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http://dx.doi.org/10.1016/j.tcm.2012.06.013DOI Listing
April 2012

HSPB1, HSPB6, HSPB7 and HSPB8 protect against RhoA GTPase-induced remodeling in tachypaced atrial myocytes.

PLoS One 2011 24;6(6):e20395. Epub 2011 Jun 24.

Department of Radiation and Stress Cell Biology, University Institute for Drug Exploration (GUIDE), University of Groningen, University Medical Center Groningen, Groningen, The Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0020395PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3123278PMC
November 2011

Effects of different small HSPB members on contractile dysfunction and structural changes in a Drosophila melanogaster model for Atrial Fibrillation.

J Mol Cell Cardiol 2011 Sep 13;51(3):381-9. Epub 2011 Jul 13.

Department of Clinical Pharmacology, University Institute for Drug Exploration, University of Groningen, University Medical Center Groningen, The Netherlands.

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http://dx.doi.org/10.1016/j.yjmcc.2011.06.008DOI Listing
September 2011

The calcium/calmodulin/kinase system and arrhythmogenic afterdepolarizations in bradycardia-related acquired long-QT syndrome.

Circ Arrhythm Electrophysiol 2009 Jun 17;2(3):295-304. Epub 2009 Apr 17.

Department of Medicine and Research Center, Montreal Heart Institute and Université de Montréal, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1161/CIRCEP.108.815654DOI Listing
June 2009

Calpain mediates cardiac troponin degradation and contractile dysfunction in atrial fibrillation.

J Mol Cell Cardiol 2008 Nov 11;45(5):685-93. Epub 2008 Sep 11.

Department of Radiation and Stress Cell Biology, University Institute for Drug Exploration (GUIDE), University of Groningen, University Medical Center Groningen, The Netherlands.

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http://dx.doi.org/10.1016/j.yjmcc.2008.08.012DOI Listing
November 2008

Cellular signaling underlying atrial tachycardia remodeling of L-type calcium current.

Circ Res 2008 Oct 21;103(8):845-54. Epub 2008 Aug 21.

Montreal Heart Institute and Department of Medicine, Université de Montéal, Quebec, Canada

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https://www.ahajournals.org/doi/10.1161/CIRCRESAHA.108.17546
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http://dx.doi.org/10.1161/CIRCRESAHA.108.175463DOI Listing
October 2008

Heat shock proteins as molecular targets for intervention in atrial fibrillation.

Cardiovasc Res 2008 Jun 7;78(3):422-8. Epub 2008 Mar 7.

Department of Radiation and Stress Cell Biology, University of Groningen, University Medical Center Groningen, A. Deusinglaan 1, 9713 AV Groningen, The Netherlands.

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http://dx.doi.org/10.1093/cvr/cvn060DOI Listing
June 2008

Effects of a heat shock protein inducer on the atrial fibrillation substrate caused by acute atrial ischaemia.

Cardiovasc Res 2008 Apr 31;78(1):63-70. Epub 2008 Jan 31.

Department of Medicine and Research Center, Montreal Heart Institute and Université de Montréal, 5000 Belanger St. E., Montreal, Quebec, Canada H1T 1C8.

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https://academic.oup.com/cardiovascres/article-lookup/doi/10
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http://dx.doi.org/10.1093/cvr/cvn019DOI Listing
April 2008

Beat shock proteins and atrial fibrillation.

Cell Stress Chaperones 2007 ;12(2):97-100

Department of Cell Biology, Clinical Pharmacology, and Cardiology, University Medical Center Groningen and University of Groningen, The Netherlands.

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http://dx.doi.org/10.1379/csc-285.1DOI Listing
August 2007

Effects of simvastatin on the development of the atrial fibrillation substrate in dogs with congestive heart failure.

Cardiovasc Res 2007 Apr 11;74(1):75-84. Epub 2007 Jan 11.

Department of Medicine and Research Center, Montreal Heart Institute and Université de Montréal, Canada.

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http://dx.doi.org/10.1016/j.cardiores.2007.01.002DOI Listing
April 2007

Induction of heat shock response protects the heart against atrial fibrillation.

Circ Res 2006 Dec 16;99(12):1394-402. Epub 2006 Nov 16.

Department of Medicine and Research Center, Montreal Heart Institute, 5000 Belanger St E, Montreal, Quebec H1T 1C8, Canada.

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http://dx.doi.org/10.1161/01.RES.0000252323.83137.feDOI Listing
December 2006

Heat shock protein upregulation protects against pacing-induced myolysis in HL-1 atrial myocytes and in human atrial fibrillation.

J Mol Cell Cardiol 2006 Sep 31;41(3):555-62. Epub 2006 Jul 31.

Department of Radiation and Stress Cell Biology, Groningen University Institute for Drug Exploration (GUIDE), University Medical Center of Groningen, A. Deusinglaan 1, 9713 AV Groningen, The Netherlands.

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http://dx.doi.org/10.1016/j.yjmcc.2006.06.068DOI Listing
September 2006

Prednisone prevents atrial fibrillation promotion by atrial tachycardia remodeling in dogs.

Cardiovasc Res 2006 Mar 5;69(4):865-75. Epub 2006 Jan 5.

Department of Medicine and Research Center, Montreal Heart Institute and University of Montreal, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1016/j.cardiores.2005.11.028DOI Listing
March 2006

Mechanisms of atrial fibrillation: lessons from animal models.

Prog Cardiovasc Dis 2005 Jul-Aug;48(1):9-28

Department of Medicine, Montreal Heart Institute and University of Montreal, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1016/j.pcad.2005.06.002DOI Listing
November 2005

The pathology of atrial fibrillation in dogs.

J Vet Cardiol 2005 Nov 17;7(2):121-9. Epub 2005 Oct 17.

Research Center, Montreal Heart Institute and University of Montreal, QC, Canada; Department of Radiation and Stress Cell Biology, University of Groningen, The Netherlands.

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http://dx.doi.org/10.1016/j.jvc.2005.07.001DOI Listing
November 2005

Atrial fibrillation: basic mechanisms, remodeling and triggers.

J Interv Card Electrophysiol 2005 Sep;13(3):181-93

Research Center, Montreal Heart Institute and University of Montreal, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1007/s10840-005-2362-yDOI Listing
September 2005

Calpain inhibition prevents pacing-induced cellular remodeling in a HL-1 myocyte model for atrial fibrillation.

Cardiovasc Res 2004 Jun;62(3):521-8

Faculty Medical Science, Department of Radiation and Stress Cell Biology, Groningen Institute for Drug Exploration (GUIDE), University of Groningen, A.Deusinglaan 1, 9713 AV Groningen, The Netherlands.

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http://dx.doi.org/10.1016/j.cardiores.2004.02.007DOI Listing
June 2004

Molecular mechanisms of remodeling in human atrial fibrillation.

Cardiovasc Res 2002 May;54(2):315-24

Department of Radiation and Stress Cell Biology, University of Groningen, A. Deusinglaan 1, P.O. Box 30.001, 9700 RB Groningen, The Netherlands.

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http://dx.doi.org/10.1016/s0008-6363(02)00222-5DOI Listing
May 2002

Activation of proteolysis by calpains and structural changes in human paroxysmal and persistent atrial fibrillation.

Cardiovasc Res 2002 May;54(2):380-9

Department of Clinical Pharmacology, Groningen University Institute for Drug Exploration, Groningen, The Netherlands.

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http://dx.doi.org/10.1016/s0008-6363(02)00289-4DOI Listing
May 2002