Bharti Mackness

Bharti Mackness

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Bharti Mackness

Bharti Mackness

Publications by authors named "Bharti Mackness"

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Corrigendum to "Unexpectedly higher diazoxon hydrolysis by serum paraoxonase-1 in coronary heart disease" [Clinical Biochemistry 65 (2019) 21-23].

Clin Biochem 2019 04 6;66:106. Epub 2019 Mar 6.

Avda. Princip D'Espanya, 43892 Miami Playa, Tarragona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.clinbiochem.2019.03.001DOI Listing
April 2019

Unexpectedly higher diazoxon hydrolysis by serum paraoxonase-1 in coronary heart disease.

Clin Biochem 2019 Mar 16;65:21-23. Epub 2019 Jan 16.

Avda. Princip D'Espanya, 43892 Miami Playa, Tarragona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.clinbiochem.2019.01.003DOI Listing
March 2019

Paraoxonase-1 inhibits oxidized low-density lipoprotein-induced metabolic alterations and apoptosis in endothelial cells: a nondirected metabolomic study.

Mediators Inflamm 2013 22;2013:156053. Epub 2013 May 22.

Unitat de Recerca Biomèdica, Hospital Universitari de Sant Joan, Institut d'Investigació Sanitària Pere Virgili, Universitat Rovira i Virgili, C Sant Joan, 43201 Reus, Catalonia, Spain.

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http://dx.doi.org/10.1155/2013/156053DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674710PMC
December 2013

Impaired paraoxonase-1 status in obese children. Relationships with insulin resistance and metabolic syndrome.

Clin Biochem 2013 Dec 10;46(18):1830-6. Epub 2013 Sep 10.

Unitat de Pediatria, Institut d'Investigació Sanitària Pere Virgili, Facultat de Medicina i Ciències de la Salut, Universitat Rovira i Virgili, Reus, Spain.

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http://dx.doi.org/10.1016/j.clinbiochem.2013.08.020DOI Listing
December 2013

Paraoxonase-1 is associated with corneal endothelial cell alterations in patients with chronic obstructive pulmonary disease.

Invest Ophthalmol Vis Sci 2013 Aug 28;54(8):5852-8. Epub 2013 Aug 28.

Ophthalmology Service, Hospital Universitari Sant Joan de Reus, Institut d'Investigació Sanitària Pere Virgili, Universitat Rovira i Virgili, Reus, Catalonia, Spain.

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http://dx.doi.org/10.1167/iovs.13-11951DOI Listing
August 2013

Targeting paraoxonase-1 in atherosclerosis.

Expert Opin Ther Targets 2013 Jul 10;17(7):829-37. Epub 2013 Apr 10.

AVDA Princip D'Espanya No 152, Miami Playa, Tarragona, Spain.

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http://dx.doi.org/10.1517/14728222.2013.790367DOI Listing
July 2013

Paraoxonase-1 deficiency is associated with severe liver steatosis in mice fed a high-fat high-cholesterol diet: a metabolomic approach.

J Proteome Res 2013 Apr 8;12(4):1946-55. Epub 2013 Mar 8.

Unitat de Recerca Biomèdica, Hospital Universitari de Sant Joan, Institut d'Investigació Sanitària Pere Virgili, Universitat Rovira i Virgili , Reus, Spain.

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http://dx.doi.org/10.1021/pr400050uDOI Listing
April 2013

Serum paraoxonase-3 concentration is associated with insulin sensitivity in peripheral artery disease and with inflammation in coronary artery disease.

Atherosclerosis 2012 Feb 22;220(2):545-51. Epub 2011 Nov 22.

Centre de Recerca Biomèdica, Hospital Universitari de Sant Joan, Institut d'Investigació Sanitària Pere Virgili, Universitat Rovira i Virgili, C. Sant Joan s/n, 43201 Reus, Catalonia, Spain.

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http://dx.doi.org/10.1016/j.atherosclerosis.2011.11.021DOI Listing
February 2012

Coincubation of PON1, APO A1, and LCAT increases the time HDL is able to prevent LDL oxidation.

IUBMB Life 2012 Feb 20;64(2):157-61. Epub 2011 Dec 20.

Division of Cardiovascular Research, University of Manchester, Oxford Road, Manchester M13 9WL, UK.

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http://dx.doi.org/10.1002/iub.588DOI Listing
February 2012

Monocyte chemoattractant protein-1 and paraoxonase-1 and 3 levels in patients with sepsis treated in an intensive care unit: a preliminary report.

Clin Chem Lab Med 2012 Feb 1;50(8):1409-15. Epub 2012 Feb 1.

Laboratori d'Anàlisis Clíniques, Hospital Verge de la Cinta, Institut d'Investigació Sanitària Pere Virgili, Universitat Rovira i Virgili, Tortosa, Spain.

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http://dx.doi.org/10.1515/cclm-2011-0896DOI Listing
February 2012

Serum paraoxonase-3 concentration in HIV-infected patients. Evidence for a protective role against oxidation.

J Lipid Res 2012 Jan 14;53(1):168-74. Epub 2011 Oct 14.

Centre de Recerca Biomèdica, Hospital Universitari de Sant Joan, Institut d'Investigació Sanitària Pere Virgili, Universitat Rovira i Virgili, Reus, Spain.

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http://dx.doi.org/10.1194/jlr.P018457DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3243473PMC
January 2012

Serum paraoxonase-3 concentration is associated with the severity of hepatic impairment in patients with chronic liver disease.

Clin Biochem 2011 Nov 10;44(16):1320-4. Epub 2011 Aug 10.

Centre de Recerca Biomèdica, Hospital Universitari de Sant Joan, Institut d'Investigació Sanitària Pere Virgili, Universitat Rovira i Virgili, 43201 Reus, Catalonia, Spain.

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http://dx.doi.org/10.1016/j.clinbiochem.2011.08.003DOI Listing
November 2011

Effect of dilution on high-density lipoprotein associated paraoxonase-1 activity.

Clin Biochem 2011 Oct 10;44(14-15):1270-1. Epub 2011 Aug 10.

PONTECH ART, Calle de L'Argelagar, 43840 Salou, Tarragona, Spain.

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http://dx.doi.org/10.1016/j.clinbiochem.2011.08.002DOI Listing
October 2011

Anti-inflammatory properties of paraoxonase-1 in atherosclerosis.

Adv Exp Med Biol 2010 ;660:143-51

Universitat Rovari i Virgili, Center de Recerca Biomedica Hospital Universitari de Sant Joan, 43201, Reus, Spain.

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http://link.springer.com/10.1007/978-1-60761-350-3_13
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http://dx.doi.org/10.1007/978-1-60761-350-3_13DOI Listing
September 2011

Cholesteryl-ester transfer protein enhances the ability of high-density lipoprotein to inhibit low-density lipoprotein oxidation.

IUBMB Life 2011 Sep 3;63(9):772-4. Epub 2011 Aug 3.

Division of Cardiovascular Sciences, University of Manchester, Manchester, UK.

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http://doi.wiley.com/10.1002/iub.508
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http://dx.doi.org/10.1002/iub.508DOI Listing
September 2011

Measurement of serum PON-3 concentration: method evaluation, reference values, and influence of genotypes in a population-based study.

J Lipid Res 2011 May 17;52(5):1055-61. Epub 2011 Feb 17.

Centre de Recerca Biomèdica, Hospital Universitari de Sant Joan, Institut d'Investigació Sanitària Pere Virgili, Universitat Rovira i Virgili, Catalonia, Spain.

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http://dx.doi.org/10.1194/jlr.D014134DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3073463PMC
May 2011

'Dippers' flu' and its relationship to PON1 polymorphisms.

Occup Environ Med 2011 Mar 4;68(3):211-7. Epub 2010 Oct 4.

Community and Occupational Medicine Program, Department of Medicine, 5-30 University Terrace, 8303-112 St, Edmonton, Alberta T6G1K4, Canada.

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http://dx.doi.org/10.1136/oem.2009.052126DOI Listing
March 2011

Immunohistochemical analysis of paraoxonases-1 and 3 in human atheromatous plaques.

Eur J Clin Invest 2011 Mar 21;41(3):308-14. Epub 2010 Oct 21.

Centre de Recerca Biomèdica, Hospital Universitari de Sant Joan, Institut d'Investigacions Sanitàries Pere Virgili, Universitat Rovira i Virgili, Reus, Catalunya, Spain.

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http://dx.doi.org/10.1111/j.1365-2362.2010.02411.xDOI Listing
March 2011

Tissue distribution and expression of paraoxonases and chemokines in mouse: the ubiquitous and joint localisation suggest a systemic and coordinated role.

J Mol Histol 2010 Dec 8;41(6):379-86. Epub 2010 Oct 8.

Centre de Recerca Biomèdica, Hospital Universitari de Sant Joan. Institut d´Investigació Sanitària Pere Virgili (IISPV), Universitat Rovira i Virgili, C Sant Joan s/n, 43201 Reus, Spain.

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http://dx.doi.org/10.1007/s10735-010-9299-xDOI Listing
December 2010

Human tissue distribution of paraoxonases 1 and 2 mRNA.

IUBMB Life 2010 Jun;62(6):480-2

Centre de Recerca Biomedica, Hospital Universitari de Sant Joan, C. Sant Joan S/N, Reus, Catalunya, Spain.

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http://dx.doi.org/10.1002/iub.347DOI Listing
June 2010

Decreased paraoxonase-1 activity is associated with alterations of high-density lipoprotein particles in chronic liver impairment.

Lipids Health Dis 2010 May 14;9:46. Epub 2010 May 14.

Centre de Recerca Biomèdica, Institut d'Investigació Sanitària Pere Virgili, Universitat Rovira i Virgili, C, Sant Joan s/n, 43201 Reus, Catalunya, Spain.

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http://dx.doi.org/10.1186/1476-511X-9-46DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2877049PMC
May 2010

Paraoxonase-1 gene haplotypes are associated with metabolic disturbances, atherosclerosis, and immunologic outcome in HIV-infected patients.

J Infect Dis 2010 Feb;201(4):627-34

Centre de Recerca Biomèdica, Hospital Universitari de Sant Joan, Institut d'Investigació Sanitària Pere Virgili, Lleida, Spain.

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http://dx.doi.org/10.1086/650312DOI Listing
February 2010

High-density lipoprotein: why all the fuss?

Ann Clin Biochem 2009 Jan 17;46(Pt 1):5-7. Epub 2008 Nov 17.

Pontech House, Cote Green Road, Marple Bridge, Stockport SK6 5EW, UK.

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http://dx.doi.org/10.1258/acb.2008.008133DOI Listing
January 2009

Paraoxonase-1 is related to inflammation, fibrosis and PPAR delta in experimental liver disease.

BMC Gastroenterol 2009 Jan 14;9. Epub 2009 Jan 14.

Centre de Recerca Biomèdica, Hospital Universitari de Sant Joan, Institut d'Investigacions Sanitàries Pere Virgili, Universitat Rovira i Virgili, C, Sant Joan s/n, 43201 Reus, Spain.

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http://dx.doi.org/10.1186/1471-230X-9-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2632645PMC
January 2009

Comparison of the ability of paraoxonases 1 and 3 to attenuate the in vitro oxidation of low-density lipoprotein and reduce macrophage oxidative stress.

Free Radic Biol Med 2008 Sep 6;45(6):743-8. Epub 2008 Jun 6.

Division of Cardiovascular Sciences, University of Manchester, Department of Medicine, Manchester Royal Infirmary, Oxford Road, Manchester M13 9WL, UK.

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http://dx.doi.org/10.1016/j.freeradbiomed.2008.05.024DOI Listing
September 2008

Immunohistochemical analysis of paraoxonases-1, 2, and 3 expression in normal mouse tissues.

Free Radic Biol Med 2008 Jul 11;45(2):146-57. Epub 2008 Apr 11.

Centre de Recerca Biomèdica, Hospital Universitari de Sant Joan, Institut d'Investigacions Sanitàries Pere Virgili, Universitat Rovira i Virgili, Reus, Spain.

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https://linkinghub.elsevier.com/retrieve/pii/S08915849080017
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http://dx.doi.org/10.1016/j.freeradbiomed.2008.03.023DOI Listing
July 2008

Effect of fenofibrate therapy on paraoxonase1 status in patients with low HDL-C levels.

Atherosclerosis 2008 Jan 6;196(1):122-8. Epub 2007 Apr 6.

Department of Pharmacology, Faculty of Pharmacy, Mahidol University, Sri Ayudhaya Road, Bangkok 10400, Thailand.

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http://dx.doi.org/10.1016/j.atherosclerosis.2007.03.001DOI Listing
January 2008

Serum paraoxonase-1 activity and concentration are influenced by human immunodeficiency virus infection.

Atherosclerosis 2007 Sep 30;194(1):175-81. Epub 2006 Aug 30.

Servei de Medicina Interna, Hospital Universitari de Sant Joan, Institut de Recerca en Ciències de la Salut, C. Sant Joan s/n, 43201 Reus, Spain.

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http://dx.doi.org/10.1016/j.atherosclerosis.2006.07.024DOI Listing
September 2007

Serum paraoxonase-1 in chronic alcoholics: relationship with liver disease.

Clin Biochem 2007 Jun 3;40(9-10):645-50. Epub 2007 Feb 3.

Centre de Recerca Biomèdica, Hospital Universitari de Sant Joan, Institut de Recerca en Ciències de la Salut, Reus, Spain.

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http://dx.doi.org/10.1016/j.clinbiochem.2007.01.020DOI Listing
June 2007

Paraoxonase gene polymorphism and serum activity in progressive IgA nephropathy.

J Nephrol 2006 Nov-Dec;19(6):732-8

Second Department of Medicine and Nephrological Centre, University of Pecs, Pecs, Hungary.

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April 2007

Rosiglitazone modulates fasting and post-prandial paraoxonase 1 activity in type 2 diabetic patients.

Clin Exp Pharmacol Physiol 2006 Dec;33(12):1134-7

Department of Internal Medicine, University Medical Center, Utrecht, The Netherlands.

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http://dx.doi.org/10.1111/j.1440-1681.2006.04505.xDOI Listing
December 2006

Defective metabolism of oxidized phospholipid by HDL from people with type 2 diabetes.

Diabetes 2006 Nov;55(11):3099-103

University Department of Medicine, Manchester Royal Infirmary, Oxford Road, Manchester, M13 9WL, U.K. .

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http://diabetes.diabetesjournals.org/cgi/doi/10.2337/db06-07
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http://dx.doi.org/10.2337/db06-0723DOI Listing
November 2006

Paraoxonase-1 is associated with oxidative stress, fibrosis and FAS expression in chronic liver diseases.

J Hepatol 2006 Jul 6;45(1):51-9. Epub 2006 Feb 6.

DNA Unit, Centre de Diagnòstic Biomèdic, IDIBAPS, Hospital Clínic Universitari,C. Villarroel 170, 08036-Barcelona, Spain.

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http://dx.doi.org/10.1016/j.jhep.2005.12.018DOI Listing
July 2006

Human paraoxonase-1 overexpression inhibits atherosclerosis in a mouse model of metabolic syndrome.

Arterioscler Thromb Vasc Biol 2006 Jul 20;26(7):1545-50. Epub 2006 Apr 20.

University Department of Medicine, Manchester Royal Infirmary, Oxford Road, Manchester M13 9WL, UK.

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http://dx.doi.org/10.1161/01.ATV.0000222924.62641.aaDOI Listing
July 2006

High C-reactive protein and low paraoxonase1 in diabetes as risk factors for coronary heart disease.

Atherosclerosis 2006 Jun 2;186(2):396-401. Epub 2005 Sep 2.

University Department of Medicine, Manchester Royal Infirmary, Oxford Road, Manchester M13 9WL, UK.

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http://dx.doi.org/10.1016/j.atherosclerosis.2005.07.028DOI Listing
June 2006

Paraoxonase 1 status in the Thai population.

J Hum Genet 2005 28;50(6):293-300. Epub 2005 May 28.

Department of Pharmacology, Faculty of Pharmacy, Mahidol University, Sri Ayudhaya Road, 10400, Bangkok, Thailand.

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http://dx.doi.org/10.1007/s10038-005-0255-7DOI Listing
October 2005

Paraoxonase 1 and atherosclerosis: is the gene or the protein more important?

Free Radic Biol Med 2004 Nov;37(9):1317-23

University Department of Medicine, Manchester Royal Infirmary, Oxford Road, Manchester M13 9WL, UK.

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http://dx.doi.org/10.1016/j.freeradbiomed.2004.07.034DOI Listing
November 2004

The role of paraoxonase 1 activity in cardiovascular disease: potential for therapeutic intervention.

Am J Cardiovasc Drugs 2004 ;4(4):211-7

University Department of Medicine, Manchester Royal Infirmary, Manchester, UK.

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http://dx.doi.org/10.2165/00129784-200404040-00002DOI Listing
October 2004

Paraoxonase 1 activity, concentration and genotype in cardiovascular disease.

Curr Opin Lipidol 2004 Aug;15(4):399-404

University Department of Medicine, Manchester Royal Infirmary, Manchester, UK.

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August 2004

Paraoxonase-1 inhibits oxidised LDL-induced MCP-1 production by endothelial cells.

Biochem Biophys Res Commun 2004 Jun;318(3):680-3

Department of Medicine, Manchester Royal Infirmary, Oxford Road, Manchester M13 9WL, UK.

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http://dx.doi.org/10.1016/j.bbrc.2004.04.056DOI Listing
June 2004

Paraoxonase in Persian Gulf War veterans.

J Occup Environ Med 2003 Jul;45(7):668-75

Gulf War Research Unit, King's College London, 103 Denmark Hill, London SE5 8AZ, UK.

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http://dx.doi.org/10.1097/01.jom.0000071506.96740.39DOI Listing
July 2003

Low paraoxonase activity predicts coronary events in the Caerphilly Prospective Study.

Circulation 2003 Jun 19;107(22):2775-9. Epub 2003 May 19.

University Department of Medicine, Manchester Royal Infirmary, University of Manchester, Oxford Rd, Manchester M13 9WL, UK.

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http://dx.doi.org/10.1161/01.CIR.0000070954.00271.13DOI Listing
June 2003

Increased low-density lipoprotein oxidation and impaired high-density lipoprotein antioxidant defense are associated with increased macrophage homing and atherosclerosis in dyslipidemic obese mice: LCAT gene transfer decreases atherosclerosis.

Circulation 2003 Apr 24;107(12):1640-6. Epub 2003 Mar 24.

Cardiovascular Research Unit at the Center for Experimental Surgery and Anesthesiology, Katholieke Universiteit Leuven, Campus Gasthuisberg, O&N, Herestraat 49, B-3000 Leuven, Belgium.

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http://dx.doi.org/10.1161/01.CIR.0000056523.08033.9FDOI Listing
April 2003

Paraoxonase and susceptibility to organophosphorus poisoning in farmers dipping sheep.

Pharmacogenetics 2003 Feb;13(2):81-8

University Department of Medicine, Manchester Royal Infirmary, Oxford Road, Manchester M13 9WL, UK.

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http://dx.doi.org/10.1097/01.fpc.0000054058.98065.38DOI Listing
February 2003

The effect of high-density lipoproteins on the formation of lipid/protein conjugates during in vitro oxidation of low-density lipoprotein.

Biochem Biophys Res Commun 2003 Jan;300(2):501-6

Michael Barber Centre for Mass Spectrometry, UMIST, Manchester M60 1QD, UK.

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http://dx.doi.org/10.1016/s0006-291x(02)02849-8DOI Listing
January 2003

Paraoxonase and coronary heart disease.

Atheroscler Suppl 2002 Dec;3(4):49-55

University Department of Medicine, Manchester Royal Infirmary, Oxford Road, Manchester M13 9WL, UK.

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December 2002

The paraoxonase gene family and coronary heart disease.

Curr Opin Lipidol 2002 Aug;13(4):357-62

University Department of Medicine, Manchester Royal Infirmary, UK.

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August 2002