Bharati Bapat

Bharati Bapat

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Bharati Bapat

Publications by authors named "Bharati Bapat"

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An integrative DNA methylation model for improved prognostication of postsurgery recurrence and therapy in prostate cancer patients.

Urol Oncol 2020 Feb 24;38(2):39.e1-39.e9. Epub 2019 Sep 24.

Lunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, ON; Institute of Medical Science, University of Toronto, Toronto, ON; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON; Department of Surgery and Surgical Oncology, Division of Urology, University Health Network, Toronto, ON. Electronic address:

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http://dx.doi.org/10.1016/j.urolonc.2019.08.017DOI Listing
February 2020

Methylation Markers in Prostate Biopsies Are Prognosticators for Late Biochemical Recurrence and Therapy after Surgery in Prostate Cancer Patients.

J Mol Diagn 2020 Jan 9;22(1):30-39. Epub 2019 Oct 9.

Lunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, Ontario, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada; Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada; Division of Urology, Department of Surgery and Surgical Oncology, University Health Network, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.jmoldx.2019.08.003DOI Listing
January 2020

Combining urinary DNA methylation and cell-free microRNA biomarkers for improved monitoring of prostate cancer patients on active surveillance.

Urol Oncol 2019 05 16;37(5):297.e9-297.e17. Epub 2019 Feb 16.

Lunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, Ontario, Canada; Laboratory Medicine & Pathobiology, University of Toronto, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.urolonc.2019.01.031DOI Listing
May 2019

GBX2 Methylation Is a Novel Prognostic Biomarker and Improves Prediction of Biochemical Recurrence Among Patients with Prostate Cancer Negative for Intraductal Carcinoma and Cribriform Architecture.

Eur Urol Oncol 2019 May 1;2(3):231-238. Epub 2018 Sep 1.

Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, Canada; Institute of Medical Science, University of Toronto, Toronto, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada; Departments of Surgery and Surgical Oncology, Division of Urology, University Health Network, Toronto, Canada; Department of Pathology and Laboratory Medicine, University Health Network, Toronto, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.euo.2018.08.003DOI Listing
May 2019

Exploring targets of TET2-mediated methylation reprogramming as potential discriminators of prostate cancer progression.

Clin Epigenetics 2019 03 27;11(1):54. Epub 2019 Mar 27.

Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, 60 Murray Street, L6-304B, Toronto, ON, M5T 3L9, Canada.

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http://dx.doi.org/10.1186/s13148-019-0651-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6438015PMC
March 2019

Are there differences between de novo and secondary upper tract urothelial carcinoma tumours?

Can Urol Assoc J 2019 Jan 21:E292-E299. Epub 2019 Jan 21.

Division of Urology, Department of Surgical Oncology, Princess Margaret Cancer Center, University Health Network and the University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.5489/cuaj.5595DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6754256PMC
January 2019

Assessment of Serum microRNA Biomarkers to Predict Reclassification of Prostate Cancer in Patients on Active Surveillance.

J Urol 2018 06 12;199(6):1475-1481. Epub 2017 Dec 12.

Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada; Lunenfeld Tanenbaum Research Institute, Sinai Health System, Toronto, Ontario, Canada. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00225347177806
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http://dx.doi.org/10.1016/j.juro.2017.12.006DOI Listing
June 2018

Re: Urinary DNA Methylation Biomarkers for Noninvasive Prediction of Aggressive Disease in Patients with Prostate Cancer on Active Surveillance: F. Zhao, E. Olkhov-Mitsel, T. van der Kwast, J. Sykes, D. Zdravic, V. Venkateswaran, A. R. Zlotta, A. Loblaw, N. E. Fleshner, L. Klotz, D. Vesprini and B. Bapat J Urol 2017;197:335-341.

J Urol 2018 05 9;199(5):1354-1355. Epub 2018 Feb 9.

Lunenfeld-Tanenbaum Research Institute, Sinai Health System, University of Toronto, Toronto, Ontario, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.juro.2017.10.061DOI Listing
May 2018

Modulation of transcription factor binding and epigenetic regulation of the MLH1 CpG island and shore by polymorphism rs1800734 in colorectal cancer.

Epigenetics 2017 06 17;12(6):441-448. Epub 2017 Mar 17.

a Lunenfeld-Tanenbaum Research Institute, Sinai Health System , Toronto , Ontario , Canada.

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http://dx.doi.org/10.1080/15592294.2017.1305527DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5501216PMC
June 2017

Epigenome-Wide DNA Methylation Profiling Identifies Differential Methylation Biomarkers in High-Grade Bladder Cancer.

Transl Oncol 2017 Apr 3;10(2):168-177. Epub 2017 Feb 3.

Lunenfeld-Tanenbaum Research Institute, Sinai Health System, 60 Murray St., Toronto, Ontario, Canada, M5T 3L9; Department of Laboratory Medicine and Pathobiology, University of Toronto, 27 King's College Circle, Toronto, Ontario, Canada, M5S 1A1; Department of Pathology, University Health Network, 200 Elizabeth St., Toronto, Ontario, Canada, M5G 2C4. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S19365233163025
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http://dx.doi.org/10.1016/j.tranon.2017.01.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5293735PMC
April 2017

Urinary DNA Methylation Biomarkers for Noninvasive Prediction of Aggressive Disease in Patients with Prostate Cancer on Active Surveillance.

J Urol 2017 02 18;197(2):335-341. Epub 2016 Aug 18.

Lunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, Ontario, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada; Department of Pathology, University Health Network, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.juro.2016.08.081DOI Listing
February 2017

Metformin Elicits Antitumor Effects and Downregulates the Histone Methyltransferase Multiple Myeloma SET Domain (MMSET) in Prostate Cancer Cells.

Prostate 2016 12 12;76(16):1507-1518. Epub 2016 Jul 12.

Lunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1002/pros.23235DOI Listing
December 2016

Dynamic interplay between locus-specific DNA methylation and hydroxymethylation regulates distinct biological pathways in prostate carcinogenesis.

Clin Epigenetics 2016 15;8:32. Epub 2016 Mar 15.

Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON Canada ; Mount Sinai Hospital, Lunenfeld-Tanenbaum Research Institute, Toronto, ON Canada.

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http://dx.doi.org/10.1186/s13148-016-0195-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791926PMC
April 2016

Beyond the island: epigenetic biomarkers of colorectal and prostate cancer.

Methods Mol Biol 2015 ;1238:103-24

Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1007/978-1-4939-1804-1_6DOI Listing
July 2015

Molecular and clinical support for a four-tiered grading system for bladder cancer based on the WHO 1973 and 2004 classifications.

Mod Pathol 2015 May 28;28(5):695-705. Epub 2014 Nov 28.

1] Department of Pathology, Josephine Nefkens Institute, Erasmus MC, Rotterdam, The Netherlands [2] Department of Surgical Pathology, University Health Network, Toronto, ON, Canada.

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http://dx.doi.org/10.1038/modpathol.2014.154DOI Listing
May 2015

Integrated analysis of epigenomic and genomic changes by DNA methylation dependent mechanisms provides potential novel biomarkers for prostate cancer.

Oncotarget 2014 Sep;5(17):7858-69

Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital. Department of Laboratory Medicine and Pathobiology, University of Toronto. Department of Pathology, University Health Network, Toronto, Canada.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4202166PMC
http://dx.doi.org/10.18632/oncotarget.2313DOI Listing
September 2014

FGFR3 mutations, but not FGFR3 expression and FGFR3 copy-number variations, are associated with favourable non-muscle invasive bladder cancer.

Virchows Arch 2014 Aug 1;465(2):207-13. Epub 2014 Jun 1.

Department of Surgical Oncology (Urology), The Netherlands Cancer Institute - Antoni van Leeuwenhoek Hospital, Plesmanlaan 121, 1066 CX, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/s00428-014-1596-4DOI Listing
August 2014

Evaluation and prognostic significance of ACAT1 as a marker of prostate cancer progression.

Prostate 2014 Apr 6;74(4):372-80. Epub 2013 Dec 6.

Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, ON, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1002/pros.22758DOI Listing
April 2014

Novel multiplex MethyLight protocol for detection of DNA methylation in patient tissues and bodily fluids.

Sci Rep 2014 Mar 21;4:4432. Epub 2014 Mar 21.

1] Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, ON, Canada [2] Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada [3] Department of Pathology and Laboratory Medicine, University Health Network, Toronto, Ontario, Canada.

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http://www.nature.com/articles/srep04432
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http://dx.doi.org/10.1038/srep04432DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3961737PMC
March 2014

Strategies for discovery and validation of methylated and hydroxymethylated DNA biomarkers.

Cancer Med 2012 Oct 14;1(2):237-60. Epub 2012 Sep 14.

Samuel Lunenfeld Research Institute, Mount Sinai Hospital Toronto, Ontario, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1002/cam4.22DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3544446PMC
October 2012

Epigenetic biomarkers in colorectal cancer diagnostics.

Expert Rev Mol Diagn 2012 Jun;12(5):499-509

Samuel Lunenfeld Research Institute, Mount Sinai Hospital, L6-304B, Box 30, Toronto, ON M5G 1X5, Canada.

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http://dx.doi.org/10.1586/erm.12.39DOI Listing
June 2012

Correlation of ERG expression and DNA methylation biomarkers with adverse clinicopathologic features of prostate cancer.

Clin Cancer Res 2012 May 27;18(10):2896-904. Epub 2012 Mar 27.

Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1158/1078-0432.CCR-11-2901DOI Listing
May 2012

Epigenetic regulation of kallikrein-related peptidases: there is a whole new world out there.

Biol Chem 2012 Apr;393(5):319-30

Department of Laboratory Medicine and Pathobiology, University of Toronto, Ontario, Canada.

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http://dx.doi.org/10.1515/hsz-2011-0273DOI Listing
April 2012

Rac1b recruits Dishevelled and β-catenin to Wnt target gene promoters independent of Wnt3A stimulation.

Int J Oncol 2011 Oct 6;39(4):805-10. Epub 2011 Jun 6.

Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, M5T 3L9, Canada.

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http://dx.doi.org/10.3892/ijo.2011.1066DOI Listing
October 2011

Functional effects of the MLH1-93G>A polymorphism on MLH1/EPM2AIP1 promoter activity.

Oncol Rep 2011 Mar 30;25(3):809-15. Epub 2010 Dec 30.

Department of Laboratory Medicine and Pathobiology, University of Toronto, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, 1 King's College Circle, Toronto, ON, Canada.

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http://dx.doi.org/10.3892/or.2010.1129DOI Listing
March 2011

A novel and rapid method of determining the effect of unclassified MLH1 genetic variants on differential allelic expression.

J Mol Diagn 2010 Nov 23;12(6):757-64. Epub 2010 Sep 23.

Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.2353/jmoldx.2010.090240DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2963917PMC
November 2010

Epigenomics-based diagnostics.

Clin Chem 2010 Aug 14;56(8):1216-9. Epub 2010 May 14.

Department of Clinical Biochemistry, Mount Sinai Hospital and University Health Network, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1373/clinchem.2010.148007DOI Listing
August 2010

DNA methylation of HOXD3 as a marker of prostate cancer progression.

Lab Invest 2010 Jul 8;90(7):1060-7. Epub 2010 Mar 8.

Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, ON, Canada.

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http://dx.doi.org/10.1038/labinvest.2010.57DOI Listing
July 2010

How to Deal with Batch Effect in Sequential Microarray Experiments?

Mol Inform 2010 May 14;29(5):387-93. Epub 2010 May 14.

Dalla Lana School of Public Health, University of Toronto, Toronto M5T 3M7, Ontario Canada.

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http://dx.doi.org/10.1002/minf.200900019DOI Listing
May 2010

A novel complex mutation in MSH2 contributes to both Muir-Torre and Lynch Syndrome.

J Hum Genet 2010 Jan 13;55(1):37-41. Epub 2009 Nov 13.

Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1038/jhg.2009.119DOI Listing
January 2010

Predicting favourable prognosis of urothelial carcinoma: gene expression and genome profiling.

Curr Opin Urol 2009 Sep;19(5):516-21

Department of Pathology, University Health Network and University of Toronto, Canada.

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http://dx.doi.org/10.1097/MOU.0b013e32832eb45fDOI Listing
September 2009

Planning the human variome project: the Spain report.

Authors:
Jim Kaput Richard G H Cotton Lauren Hardman Michael Watson Aida I Al Aqeel Jumana Y Al-Aama Fahd Al-Mulla Santos Alonso Stefan Aretz Arleen D Auerbach Bharati Bapat Inge T Bernstein Jong Bhak Stacey L Bleoo Helmut Blöcker Steven E Brenner John Burn Mariona Bustamante Rita Calzone Anne Cambon-Thomsen Michele Cargill Paola Carrera Lawrence Cavedon Yoon Shin Cho Yeun-Jun Chung Mireille Claustres Garry Cutting Raymond Dalgleish Johan T den Dunnen Carlos Díaz Steven Dobrowolski M Rosário N dos Santos Rosemary Ekong Simon B Flanagan Paul Flicek Yoichi Furukawa Maurizio Genuardi Ho Ghang Maria V Golubenko Marc S Greenblatt Ada Hamosh John M Hancock Ross Hardison Terence M Harrison Robert Hoffmann Rania Horaitis Heather J Howard Carol Isaacson Barash Neskuts Izagirre Jongsun Jung Toshio Kojima Sandrine Laradi Yeon-Su Lee Jong-Young Lee Vera L Gil-da-Silva-Lopes Finlay A Macrae Donna Maglott Makia J Marafie Steven G E Marsh Yoichi Matsubara Ludwine M Messiaen Gabriela Möslein Mihai G Netea Melissa L Norton Peter J Oefner William S Oetting James C O'Leary Ana Maria Oller de Ramirez Mark H Paalman Jillian Parboosingh George P Patrinos Giuditta Perozzi Ian R Phillips Sue Povey Suyash Prasad Ming Qi David J Quin Rajkumar S Ramesar C Sue Richards Judith Savige Dagmar G Scheible Rodney J Scott Daniela Seminara Elizabeth A Shephard Rolf H Sijmons Timothy D Smith María-Jesús Sobrido Toshihiro Tanaka Sean V Tavtigian Graham R Taylor Jon Teague Thoralf Töpel Mollie Ullman-Cullere Joji Utsunomiya Henk J van Kranen Mauno Vihinen Elizabeth Webb Thomas K Weber Meredith Yeager Young I Yeom Seon-Hee Yim Hyang-Sook Yoo

Hum Mutat 2009 Apr;30(4):496-510

Division of Personalised Nutrition and Medicine, FDA/National Center for Toxicological Research, Jefferson, Arkansas 72079, USA.

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http://compbio.berkeley.edu/people/brenner/pubs/kaput-2009-h
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http://doi.wiley.com/10.1002/humu.20972
Publisher Site
http://dx.doi.org/10.1002/humu.20972DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5879779PMC
April 2009

The association of tumor microsatellite instability phenotype with family history of colorectal cancer.

Cancer Epidemiol Biomarkers Prev 2009 Mar 3;18(3):967-75. Epub 2009 Mar 3.

Department of Pathology and Lab Medicine, Mount Sinai Hospital, and Samuel Lunenfeld Research Institute, University of Toronto, 60 Murray Street, Box 30, Toronto, M5T 3L9, Ontario, Canada.

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http://dx.doi.org/10.1158/1055-9965.EPI-08-0878DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2763617PMC
March 2009

Cyclin D1 Pro241Pro (CCND1-G870A) polymorphism is associated with increased cancer risk in human populations: a meta-analysis.

Cancer Epidemiol Biomarkers Prev 2008 Oct;17(10):2773-81

Department of Pathology and Laboratory Medicine, Mount Sinai Hospital, 60 Murray Street, Room L6-304, Box 29, Toronto, Ontario, Canada M5T 3L9.

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http://dx.doi.org/10.1158/1055-9965.EPI-08-0169DOI Listing
October 2008

Systemic Erdheim-Chester disease.

Virchows Arch 2008 Feb 10;452(2):221-7. Epub 2008 Jan 10.

Department of Pathology and Laboratory Medicine, Mount Sinai Hospital, Toronto, ON, Canada.

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http://dx.doi.org/10.1007/s00428-007-0538-9DOI Listing
February 2008

The MLH1 variants p.Arg265Cys and p.Lys618Ala affect protein stability while p.Leu749Gln affects heterodimer formation.

Hum Mutat 2008 Feb;29(2):332

Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada.

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http://dx.doi.org/10.1002/humu.9523DOI Listing
February 2008

MSH2 118T>C and MSH6 159C>T promoter polymorphisms and the risk of colorectal cancer.

Carcinogenesis 2007 Dec 17;28(12):2575-80. Epub 2007 Oct 17.

Department of Pathology and Laboratory Medicine, Mount Sinai Hospital, Toronto, Ontario M5T 3L9, Canada.

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http://dx.doi.org/10.1093/carcin/bgm229DOI Listing
December 2007

Suppression of nuclear Wnt signaling leads to stabilization of Rac1 isoforms.

FEBS Lett 2007 Oct 17;581(25):4850-6. Epub 2007 Sep 17.

Samuel Lunenfeld Research Institute, Mount Sinai Hospital, 60 Murray Street, Room L6-304-4, Toronto, Canada.

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http://dx.doi.org/10.1016/j.febslet.2007.09.013DOI Listing
October 2007

Does early colectomy increase desmoid risk in familial adenomatous polyposis?

Clin Gastroenterol Hepatol 2007 Oct;5(10):1190-4

Familial Gastrointestinal Cancer Registry and Department of Surgery, Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.cgh.2007.06.010DOI Listing
October 2007

An association between the 4G polymorphism in the PAI-1 promoter and the development of aggressive fibromatosis (desmoid tumor) in familial adenomatous polyposis patients.

Fam Cancer 2007 ;6(1):89-95

Program in Developmental Biology, The Hospital for Sick Children, University of Toronto, Ontario, Canada.

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http://dx.doi.org/10.1007/s10689-006-9109-5DOI Listing
September 2007

MYH mutations are rare in prostate cancer.

J Cancer Res Clin Oncol 2007 Jun 12;133(6):373-8. Epub 2007 Jan 12.

Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, ON, Canada.

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http://dx.doi.org/10.1007/s00432-006-0181-xDOI Listing
June 2007

Germline MYH mutations in a clinic-based series of Canadian multiple colorectal adenoma patients.

J Surg Oncol 2007 May;95(6):499-506

Centre for Cancer Genetics, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1002/jso.20724DOI Listing
May 2007

Rho GTPases and cancer.

Prog Mol Subcell Biol 2005 ;40:29-53

Samuel Lunenfeld Research Institute, 9th Floor, Room 992B, Mount Sinai Hospital, 600 University Avenue, Toronto, Ontario, M5G 1X5 Canada.

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http://dx.doi.org/10.1007/3-540-27671-8_2DOI Listing
January 2007

Peutz-Jeghers syndrome diagnosed in a schizophrenic patient with a large deletion in the STK11 gene.

Dig Dis Sci 2006 Sep 22;51(9):1567-70. Epub 2006 Aug 22.

VAMC, Department of Medicine, Division of Gastroenterology and Surgery, Wayne State University School of Medicine, Detroit, Michigan 48201, USA.

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http://dx.doi.org/10.1007/s10620-006-9102-8DOI Listing
September 2006

Genetic instability in human tumors.

EXS 2006 (96):303-20

Department of Pathology and Laboratory Medicine, Mount Sinai Hospital, Toronto, Ontario, M5G 1X5 Canada.

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http://dx.doi.org/10.1007/3-7643-7378-4_13DOI Listing
February 2006

Cyclooxygenase-2 knockdown by RNA interference in colon cancer.

Int J Oncol 2006 Feb;28(2):543-9

Department of Pathology and Laboratory Medicine, Mount Sinai Hospital, Toronto, ON, Canada.

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February 2006

Genotype and phenotype of patients with both familial adenomatous polyposis and thyroid carcinoma.

Fam Cancer 2003 ;2(2):95-9

University California San Francisco, Department of Medicine, Comprehensive Cancer Center, San Francisco, California, USA.

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http://dx.doi.org/10.1023/a:1025762706854DOI Listing
January 2004

Genomic instability and cancer.

Curr Mol Med 2003 Nov;3(7):589-96

Department of Pathology and Laboratory Medicine, Mount Sinai Hospital, Toronto, Canada.

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http://dx.doi.org/10.2174/1566524033479456DOI Listing
November 2003

Hereditary nonpolyposis colorectal cancer--molecular basis.

Surgery 2003 Jul;134(1):29-33

Department of Surgery, Centre for Cancer Genetics, Samuel Lunenfeld Research Institute, Mount Sinai Hospital, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1067/msy.2003.176DOI Listing
July 2003

Methylation of adenomatous polyposis coli in endometrial cancer occurs more frequently in tumors with microsatellite instability phenotype.

Cancer Res 2002 Jul;62(13):3663-6

Samuel Lunenfeld Research Institute, Department of Pathology and Laboratory Medicine, Mount Sinai Hospital, Toronto, Ontario, M5G 1X5, Canada.

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July 2002

Genes involved in DNA repair are mutational targets in endometrial cancers with microsatellite instability.

Cancer Res 2002 Jul;62(14):4095-9

Samuel Lunenfeld Research Institute, Toronto, Ontario, M5G 1X5 Canada.

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July 2002

Considerations when analyzing the methylation status of PTEN tumor suppressor gene.

Am J Pathol 2002 Mar;160(3):795-800

Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1867163PMC
http://dx.doi.org/10.1016/S0002-9440(10)64902-4DOI Listing
March 2002