Beth C Holbrook

Beth C Holbrook

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Beth C Holbrook

Beth C Holbrook

Publications by authors named "Beth C Holbrook"

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The choice of linker for conjugating R848 to inactivated influenza virus determines the stimulatory capacity for innate immune cells.

Vaccine 2018 02;36(9):1174-1182

Department of Microbiology and Immunology, Biotech Place, Wake Forest School of Medicine, 575 N. Patterson Ave., Winston-Salem, NC 27101, USA. Electronic address:

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http://dx.doi.org/10.1016/j.vaccine.2018.01.035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5815857PMC
February 2018

Adjuvanting an inactivated influenza vaccine with conjugated R848 improves the level of antibody present at 6months in a nonhuman primate neonate model.

Vaccine 2017 10 28;35(45):6137-6142. Epub 2017 Sep 28.

Department of Microbiology and Immunology, Wake Forest School of Medicine, Winston-Salem, NC, United States. Electronic address:

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http://dx.doi.org/10.1016/j.vaccine.2017.09.054DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5652071PMC
October 2017

Adjuvanting an inactivated influenza vaccine with flagellin improves the function and quantity of the long-term antibody response in a nonhuman primate neonate model.

Vaccine 2016 09 8;34(39):4712-4717. Epub 2016 Aug 8.

Department of Microbiology and Immunology, Wake Forest School of Medicine, Winston-Salem, NC, United States. Electronic address:

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http://dx.doi.org/10.1016/j.vaccine.2016.08.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5017597PMC
September 2016

CD4+ T cell subset differentiation and avidity setpoint are dictated by the interplay of cytokine and antigen mediated signals.

PLoS One 2014 18;9(6):e100175. Epub 2014 Jun 18.

Department of Microbiology and Immunology, Section on Rheumatology and Immunology, Wake Forest School of Medicine, Winston-Salem, North Carolina, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0100175PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4062528PMC
October 2015

Nonhuman primate infants have an impaired respiratory but not systemic IgG antibody response following influenza virus infection.

Virology 2015 Feb 24;476:124-133. Epub 2014 Dec 24.

Department of Microbiology and Immunology, Wake Forest School of Medicine, United States. Electronic address:

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http://dx.doi.org/10.1016/j.virol.2014.12.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4323840PMC
February 2015

Coinfection with Streptococcus pneumoniae negatively modulates the size and composition of the ongoing influenza-specific CD8⁺ T cell response.

J Immunol 2014 Nov 13;193(10):5076-87. Epub 2014 Oct 13.

Department of Microbiology and Immunology, Wake Forest University School of Medicine, Winston-Salem, NC 27101

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http://dx.doi.org/10.4049/jimmunol.1400529DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4265766PMC
November 2014

In vivo modulation of avidity in highly sensitive CD8(+) effector T cells following viral infection.

Viral Immunol 2013 Oct 24;26(5):302-13. Epub 2013 Aug 24.

Department of Microbiology and Immunology, Wake Forest University School of Medicine , Winston-Salem, North Carolina.

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http://dx.doi.org/10.1089/vim.2013.0042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3797458PMC
October 2013

High viral burden restricts short-lived effector cell number at late times postinfection through increased natural regulatory T cell expansion.

J Immunol 2013 May 15;190(10):5020-9. Epub 2013 Apr 15.

Department of Microbiology and Immunology, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA.

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http://dx.doi.org/10.4049/jimmunol.1200971DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3711656PMC
May 2013

The requirement of reactive oxygen intermediates for lymphocytic choriomeningitis virus binding and growth.

Virology 2008 Sep 8;379(2):205-12. Epub 2008 Aug 8.

Department of Microbiology and Immunology, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S004268220800441
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http://dx.doi.org/10.1016/j.virol.2008.07.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2615401PMC
September 2008

Apoptosis regulators Bim and Fas function concurrently to control autoimmunity and CD8+ T cell contraction.

Immunity 2008 Feb;28(2):218-30

Department of Microbiology and Immunology, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA.

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http://dx.doi.org/10.1016/j.immuni.2007.12.014DOI Listing
February 2008

The requirement of reversible cysteine sulfenic acid formation for T cell activation and function.

J Immunol 2007 Nov;179(10):6456-67

Department of Microbiology and Immunology, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA.

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http://dx.doi.org/10.4049/jimmunol.179.10.6456DOI Listing
November 2007

Role of Bim in regulating CD8+ T-cell responses during chronic viral infection.

J Virol 2006 Sep;80(17):8627-38

Department of Microbiology and Immunology, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA.

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http://dx.doi.org/10.1128/JVI.00855-06DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1563887PMC
September 2006

Electron transport complex I is required for CD8+ T cell function.

J Immunol 2006 Jul;177(2):852-62

Department of Microbiology and Immunology, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA.

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http://dx.doi.org/10.4049/jimmunol.177.2.852DOI Listing
July 2006

Partial reconstitution of virus-specific memory CD8+ T cells following whole body gamma-irradiation.

Virology 2006 Apr 30;348(1):47-56. Epub 2006 Jan 30.

Department of Microbiology and Immunology, 5100A Gray Building, Wake Forest University School of Medicine, Winston-Salem, NC 27157, USA.

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http://dx.doi.org/10.1016/j.virol.2005.12.030DOI Listing
April 2006