Bertrand Le Bourdonnec

Bertrand Le Bourdonnec

UNVERIFIED PROFILE

Are you Bertrand Le Bourdonnec?   Register this Author

Register author
Bertrand Le Bourdonnec

Bertrand Le Bourdonnec

Publications by authors named "Bertrand Le Bourdonnec"

Are you Bertrand Le Bourdonnec?   Register this Author

26Publications

359Reads

10Profile Views

Comprehensive survey of chemical libraries for drug discovery and chemical biology: 2009.

J Comb Chem 2010 Nov 5;12(6):765-806. Epub 2010 Oct 5.

Adolor Corporation, 700 Pennsylvania Drive, Exton, Pennsylvania 19341, USA.

View Article

Download full-text PDF

Source
http://pubs.acs.org/doi/abs/10.1021/cc100128w
Publisher Site
http://dx.doi.org/10.1021/cc100128wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4140011PMC
November 2010

Comprehensive survey of chemical libraries for drug discovery and chemical biology: 2008.

J Comb Chem 2009 Sep-Oct;11(5):739-90

Adolor Corporation, 700 Pennsylvania Drive, Exton, Pennsylvania 19341, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/cc9000828DOI Listing
December 2009

Medicinal chemistry strategies to reduce CYP2D6 inhibitory activity of lead candidates.

Curr Med Chem 2009 ;16(24):3093-121

Department of Chemistry, Adolor Corporation, Exton, PA 19341, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/092986709788803033DOI Listing
November 2009

Novel pyridine derivatives as potent and selective CB2 cannabinoid receptor agonists.

Bioorg Med Chem Lett 2009 Oct 21;19(20):5931-5. Epub 2009 Aug 21.

Department of Chemistry, Adolor Corporation, 700 Pennsylvania Drive, Exton, PA 19341, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bmcl.2009.08.063DOI Listing
October 2009

Comprehensive survey of chemical libraries for drug discovery and chemical biology: 2007.

J Comb Chem 2008 Nov-Dec;10(6):753-802

Adolor Corporation, 700 Pennsylvania Drive, Exton, Pennsylvania 19341, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/cc800119zDOI Listing
December 2008

Comprehensive survey of chemical libraries for drug discovery and chemical biology: 2006.

J Comb Chem 2007 Nov-Dec;9(6):855-902. Epub 2007 Sep 19.

Adolor Corporation, 700 Pennsylvania Drive, Exton, Pennsylvania 19341, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/cc700111eDOI Listing
February 2008

Discovery of a series of aminopiperidines as novel iNOS inhibitors.

Bioorg Med Chem Lett 2008 Jan 25;18(1):336-43. Epub 2007 Oct 25.

Department of Chemistry, Adolor Corporation, 700 Pennsylvania Drive, Exton, PA 19341, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bmcl.2007.10.073DOI Listing
January 2008

Mu opioid receptor antagonists: recent developments.

ChemMedChem 2007 Nov;2(11):1552-70

Department of Medicinal Chemistry, Adolor Corporation, 700 Pennsylvania Drive, Exton, PA 19341, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/cmdc.200700143DOI Listing
November 2007

o-Naphthalenedicarboxaldehyde derivative of 7'-aminonaltrindole as a selective delta-opioid receptor affinity label.

J Med Chem 2007 Jul 8;50(14):3392-6. Epub 2007 Jun 8.

Department of Medicinal Chemistry, College of Pharmacy, University of Minnesota, Minneapolis, Minnesota 55455, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/jm061194hDOI Listing
July 2007

Synthesis and pharmacological evaluation of novel octahydro-1H-pyrido[1,2-a]pyrazine as mu-opioid receptor antagonists.

J Med Chem 2006 Dec;49(25):7290-306

Department of Chemistry, Adolor Corporation, 700 Pennsylvania Drive, Exton, Pennsylvania 19341, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/jm0604878DOI Listing
December 2006

Comprehensive survey of combinatorial library synthesis: 2005.

J Comb Chem 2006 Sep-Oct;8(5):597-635

Adolor Corporation, 700 Pennsylvania Drive, Exton, Pennsylvania 19341, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/cc060095mDOI Listing
November 2006

trans-3,4-dimethyl-4-(3-carboxamidophenyl)piperidines: a novel class of micro-selective opioid antagonists.

Bioorg Med Chem Lett 2003 Dec;13(24):4459-62

Department of Chemistry, Adolor Corporation, 700 Pennsylvania Drive, Exton, PA 19341, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bmcl.2003.09.012DOI Listing
December 2003

Comparison of 3D structures and AT(1) binding properties of pyrazolidine-3,5-diones and tetrahydropyridazine-3,6-diones with parent antihypertensive drug irbesartan.

J Med Chem 2002 Oct;45(21):4794-8

Institut de Chimie Pharmaceutique Albert Lespagnol, Université de Lille 2, Rue du Professeur Laguesse, BP 83, F-59006 Lille, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/jm010457zDOI Listing
October 2002

Naphthalene dicarboxaldehyde as an electrophilic fluorogenic moiety for affinity labeling: application to opioid receptor affinity labels with greatly improved fluorogenic properties.

J Med Chem 2002 Jul;45(14):2887-90

Department of Medicinal Chemistry, College of Pharmacy, School of Medicine, University of Minnesota, Minneapolis, MN 55455, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/jm015586uDOI Listing
July 2002