Publications by authors named "Bertrand Friguet"

100Publications

Mitochondrial Lon protease - depleted HeLa cells exhibit proteome modifications related to protein quality control, stress response and energy metabolism.

Free Radic Biol Med 2020 02 3;148:83-95. Epub 2020 Jan 3.

Sorbonne Université, CNRS, INSERM, Institut de Biologie Paris-Seine, Biological Adaptation and Aging, B2A-IBPS, F-75005, Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.freeradbiomed.2019.12.039DOI Listing
February 2020

Proteome Oxidative Modifications and Impairment of Specific Metabolic Pathways During Cellular Senescence and Aging.

Proteomics 2020 03 15;20(5-6):e1800421. Epub 2019 Oct 15.

Sorbonne Université, CNRS, INSERM, Institut de Biologie Paris-Seine, Biological Adaptation and Ageing, B2A-IBPS, F-75005, Paris, France.

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http://dx.doi.org/10.1002/pmic.201800421DOI Listing
March 2020

Effects of the selective inhibition of proteasome caspase-like activity by CLi a derivative of nor-cerpegin in dystrophic mdx mice.

PLoS One 2019 23;14(4):e0215821. Epub 2019 Apr 23.

Sorbonne Université, Institut de Biologie Paris-Seine (IBPS), CNRS UMR 8256, Inserm ERL U1164, Biological Adaptation and Ageing, Paris, France.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0215821PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6478376PMC
January 2020

The Oxidized Protein Repair Enzymes Methionine Sulfoxide Reductases and Their Roles in Protecting against Oxidative Stress, in Ageing and in Regulating Protein Function.

Antioxidants (Basel) 2018 Dec 12;7(12). Epub 2018 Dec 12.

Sorbonne Université, CNRS, INSERM, Institut de Biologie Paris-Seine, Biological Adaptation and Ageing, B2A-IBPS, F-75005 Paris, France.

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http://dx.doi.org/10.3390/antiox7120191DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6316033PMC
December 2018

Improvement of Dystrophic Muscle Fragility by Short-Term Voluntary Exercise through Activation of Calcineurin Pathway in mdx Mice.

Am J Pathol 2018 11 22;188(11):2662-2673. Epub 2018 Aug 22.

Research Center in Myology, Association Institute of Myology, Sorbonne University, INSERM, UMRS974, Paris, France; Paris Descartes University, Sorbonne Paris Cité, Paris, France. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00029440183002
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http://dx.doi.org/10.1016/j.ajpath.2018.07.015DOI Listing
November 2018

Proteome oxidative carbonylation during oxidative stress-induced premature senescence of WI-38 human fibroblasts.

Mech Ageing Dev 2018 03 27;170:59-71. Epub 2017 Jul 27.

Sorbonne Universités, UPMC Univ Paris 06, UMR 8256, Biological adaptation and ageing-IBPS, F-75005 Paris, France; CNRS UMR 8256, F-75005 Paris, France; INSERM U1164, F-75005 Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.mad.2017.07.005DOI Listing
March 2018

Impaired energy metabolism of senescent muscle satellite cells is associated with oxidative modifications of glycolytic enzymes.

Aging (Albany NY) 2016 12;8(12):3375-3389

Sorbonne Universités, UPMC Univ Paris 06, UMR 8256, Biological Adaptation and Ageing- IBPS, CNRS UMR 8256, INSERM U1164, Paris, France.

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http://dx.doi.org/10.18632/aging.101126DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5270674PMC
December 2016

Circadian modulation of proteasome activity and accumulation of oxidized protein in human embryonic kidney HEK 293 cells and primary dermal fibroblasts.

Free Radic Biol Med 2016 05 2;94:195-207. Epub 2016 Mar 2.

Sorbonne Universités, UPMC Univ Paris 06, UMR 8256, Biological Adaptation and Ageing-IBPS, F-75005 Paris, France; CNRS UMR-8256, F-75005 Paris, France; INSERM U1164, F-75005 Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.freeradbiomed.2016.02.037DOI Listing
May 2016

The glyoxalase enzymes are differentially localized in epidermis and regulated during ageing and photoageing.

Exp Dermatol 2016 06 12;25(6):492-4. Epub 2016 May 12.

Sorbonne Universités, UPMC Université Paris 06, UMR 8256 Biological Adaptation and Ageing - IBPS, Paris, France.

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http://dx.doi.org/10.1111/exd.12995DOI Listing
June 2016

Hepatocellular carcinoma protein carbonylation in virus C and metabolic syndrome patients.

Free Radic Biol Med 2014 Oct 10;75 Suppl 1:S40. Epub 2014 Dec 10.

Institut national de la santé et de la recherche médicale (U1001), Paris, France.

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http://dx.doi.org/10.1016/j.freeradbiomed.2014.10.789DOI Listing
October 2014

Role of Oxidized Protein Repair in Human Skeletal Muscle.

Free Radic Biol Med 2014 Oct 10;75 Suppl 1:S39. Epub 2014 Dec 10.

Sorbonne Universités, UPMC Univ Paris 06, CNRS, UMR-8256, Biological Adaptation and Ageing, ERL INSERM U1164, Paris, France.

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https://linkinghub.elsevier.com/retrieve/pii/S08915849140128
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http://dx.doi.org/10.1016/j.freeradbiomed.2014.10.787DOI Listing
October 2014

Effects of Lon protease down-regulation on the mitochondrial function and proteome.

Free Radic Biol Med 2014 Oct 10;75 Suppl 1:S32-3. Epub 2014 Dec 10.

UMR5254 CNRS UPPA, Laboratory of Bio-inorganic Analytical Chemistry (Université de Pau et des Pays de l'Adour), Pau, France.

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http://dx.doi.org/10.1016/j.freeradbiomed.2014.10.767DOI Listing
October 2014

Oxi-DIGE: A novel proteomic approach for detecting and quantifying carbonylated proteins.

Free Radic Biol Med 2014 Oct 10;75 Suppl 1:S23. Epub 2014 Dec 10.

Sorbonne Universités, UPMC Univ Paris 06 (CNRS UMR 8256, INSERM U1164), Biological adaptation and aging - IBPS, France.

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http://dx.doi.org/10.1016/j.freeradbiomed.2014.10.739DOI Listing
October 2014

Impaired metabolism of senescent muscle satellite cells is associated with oxidative modifications of glycolytic enzymes.

Free Radic Biol Med 2014 Oct 10;75 Suppl 1:S23. Epub 2014 Dec 10.

Sorbonne Universités, UPMC Univ Paris 06 (CNRS UMR 8256, INSERM U1164), Biological adaptation and aging - IBPS, France.

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http://dx.doi.org/10.1016/j.freeradbiomed.2014.10.738DOI Listing
October 2014

Skin protection against dicarbonyl stress by the glyoxalase system.

Free Radic Biol Med 2014 Oct 10;75 Suppl 1:S19-20. Epub 2014 Dec 10.

Sorbonne Universités; CNRS, UMR 8256, « Biological Adaptation and Ageing »; INSERM, ERL U1164; UPMC Université Paris 06, Paris, France.

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http://dx.doi.org/10.1016/j.freeradbiomed.2014.10.635DOI Listing
October 2014

Circadian modulation of proteasome activities and removal of carbonylated proteins.

Free Radic Biol Med 2014 Oct 10;75 Suppl 1:S18. Epub 2014 Dec 10.

Sorbonne Universités; UMR8256-UPMC-CNRS, ERL INSERM U1164 (Biological Adaptation and Ageing), Paris, France.

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http://dx.doi.org/10.1016/j.freeradbiomed.2014.10.631DOI Listing
October 2014

CD4(+) T cell surface alpha enolase is lower in older adults.

Mech Ageing Dev 2015 Dec 1;152:56-62. Epub 2015 Oct 1.

Life and Health Sciences, Aston Research Centre for Healthy Ageing, Aston University, Birmingham B4 7ET, UK. Electronic address:

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http://dx.doi.org/10.1016/j.mad.2015.09.005DOI Listing
December 2015

AMPK Signaling Involvement for the Repression of the IL-1β-Induced Group IIA Secretory Phospholipase A2 Expression in VSMCs.

PLoS One 2015 10;10(7):e0132498. Epub 2015 Jul 10.

Sorbonne Universités, Université Pierre et Marie Curie, Biological Adaptation and Ageing (B2A) CNRS UMR8256/INSERM ERL-U1064, F-75005 Paris, France.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0132498PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4498592PMC
April 2016

Oxidative proteome alterations during skeletal muscle ageing.

Redox Biol 2015 Aug 3;5:267-274. Epub 2015 Jun 3.

Sorbonne Universités, UPMC Univ Paris 06, UMR 8256, Biological Adaptation and Ageing-IBPS, Paris F-75005, France; CNRS UMR-8256, Paris F-75005, France; Inserm U1164, Paris F-75005, France. Electronic address:

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http://dx.doi.org/10.1016/j.redox.2015.05.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4475901PMC
August 2015

Protein modification and maintenance systems as biomarkers of ageing.

Mech Ageing Dev 2015 Nov 3;151:71-84. Epub 2015 Apr 3.

Sorbonne Universités, UPMC University Paris 06, UMR 8256, Biological adaptation and ageing - IBPS, F-75005 Paris, France; CNRS-UMR 8256, F-75005 Paris, France; INSERM U1164, F-75005 Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.mad.2015.03.009DOI Listing
November 2015

The transcription factor E4F1 coordinates CHK1-dependent checkpoint and mitochondrial functions.

Cell Rep 2015 Apr 2;11(2):220-33. Epub 2015 Apr 2.

Equipe labellisée Ligue Contre le Cancer, Institut de Génétique Moléculaire de Montpellier, UMR5535, Centre National de la Recherche Scientifique (CNRS), 34293 Montpellier, France; Institut de Recherche en Cancérologie de Montpellier (IRCM), 34298 Montpellier, France; Institut National de la Santé et de la Recherche Médicale (INSERM), U1194, 34298 Montpellier, France; Université de Montpellier, 34090 Montpellier, France; Institut régional du Cancer de Montpellier, 34298 Montpellier, France. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2015.03.024DOI Listing
April 2015

Photosensitizing Activity of Endogenous Eye Lens Chromophores: An Attempt to Unravel Their Contributions to Photo-Aging and Cataract Disease.

Photochem Photobiol 2015 Jul-Aug;91(4):767-79. Epub 2015 Mar 28.

Departamento de Química Física, Facultad de Química, Pontifícia Universidad Católica de Chile, Santiago, Chile.

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http://dx.doi.org/10.1111/php.12443DOI Listing
December 2015

NLRP3 inflammasome: from a danger signal sensor to a regulatory node of oxidative stress and inflammatory diseases.

Redox Biol 2015 14;4:296-307. Epub 2015 Jan 14.

Sorbonne Universités, UPMC Univ Paris 06, UMR 8256, Biological Adaptation and Ageing - IBPS, F-75005 Paris, France; CNRS-UMR 8256, F-75005 Paris, France; Inserm U1164, F-75005 Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.redox.2015.01.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4315937PMC
June 2016

Anti-inflammatory and antiatherogenic effects of the NLRP3 inflammasome inhibitor arglabin in ApoE2.Ki mice fed a high-fat diet.

Circulation 2015 Mar 22;131(12):1061-70. Epub 2015 Jan 22.

From Sorbonne Universités, UPMC Université Paris 06, Biological Adaptation and Ageing-IBPS, Paris, France (A.A., D.C., D.F.D.M., R.E.H., B.F., K.E.H., M.R.); CNRS-UMR 8256, Paris, France (A.A., D.C., D.F.D.M., R.E.H., F.B., K.E.H., M.R.); Inserm U1164, Paris, France (A.A., D.C., D.F.D.M., R.E.H., B.F., K.E.H., M.R.); INSERM-UPS UMR 1048, Institut des Maladies Métaboliques et Cardiovasculaires, Toulouse, France (C.V., M.L.); Centre de Recherche d'Immunologie et Maladies Infectieuses, CIMI-Paris UPMC UMRS CR7, INSERM U-1135, CNRS ERL 8255, Hôpital Pitié-Salpêtrière, Paris, France (V.M.); Ulm University, Institute of Pharmacology of Natural Products and Clinical Pharmacology, Ulm, Germany (B.B., M.R.A., M.E.G., T.S., T.S.); Biochemistry Laboratory, Faculty of Medicine, TN-Monastir, Tunisia (M.-N.S.); and Centre de Recherche sur le Vieillissement, Service Gériatrique, Département de Médecine, Université de Sherbrooke, Sherbrooke, QC, Canada (T.F.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.114.013730DOI Listing
March 2015

Mitochondrial proteases and protein quality control in ageing and longevity.

Ageing Res Rev 2015 Sep 8;23(Pt A):56-66. Epub 2015 Jan 8.

Sorbonne Universités, UPMC Univ Paris 06, UMR 8256, Biological Adaptation and Ageing - IBPS, F-75005 Paris, France; CNRS-UMR 8256, F-75005 Paris, France; INSERM U1164, F-75005 Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.arr.2014.12.010DOI Listing
September 2015

Proteomics of muscle chronological ageing in post-menopausal women.

BMC Genomics 2014 Dec 23;15:1165. Epub 2014 Dec 23.

INRA, UMR 1019, Centre de Recherche en Nutrition Humaine, Université d'Auvergne, F-63122, Saint Genès Champanelle, France.

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http://dx.doi.org/10.1186/1471-2164-15-1165DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4523020PMC
December 2014

Autophagy impairment in muscle induces neuromuscular junction degeneration and precocious aging.

Cell Rep 2014 Sep 28;8(5):1509-21. Epub 2014 Aug 28.

Dulbecco Telethon Institute, Venetian Institute of Molecular Medicine, 35129 Padova, Italy; Department of Biomedical Sciences, University of Padova, 35121 Padova, Italy; Institute of Neuroscience, Consiglio Nazionale delle Ricerche, 35121 Padova, Italy; Department of Medicine, McGill University, Montreal QC H3A 0G4, Canada; Telethon Institute of Genetics and Medicine (TIGEM), 80131 Napoli, Italy. Electronic address:

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http://www.cell.com/cell-reports/pdf/S2211-1247(14)00664-0.p
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http://linkinghub.elsevier.com/retrieve/pii/S221112471400664
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http://dx.doi.org/10.1016/j.celrep.2014.07.061DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4534571PMC
September 2014

Prevention of dicarbonyl-mediated advanced glycation by glyoxalases: implication in skin aging.

Biochem Soc Trans 2014 Apr;42(2):518-22

∥LVMH Recherche, 185 avenue de Verdun, 45800 Saint-Jean-de-Braye, France.

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http://dx.doi.org/10.1042/BST20140017DOI Listing
April 2014

Annonacin, a natural lipophilic mitochondrial complex I inhibitor, increases phosphorylation of tau in the brain of FTDP-17 transgenic mice.

Exp Neurol 2014 Mar 3;253:113-25. Epub 2014 Jan 3.

Experimental Neurology, Philipps University, D-35037 Marburg, Germany; German Center for Neurodegenerative Diseases (DZNE), D-81677 Munich, Germany; Department of Neurology, Technical University Munich, D-81377 Munich, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.expneurol.2013.12.017DOI Listing
March 2014

Effect of Lon protease knockdown on mitochondrial function in HeLa cells.

Biochimie 2014 May 17;100:38-47. Epub 2013 Dec 17.

UR4 - Vieillissement, Stress, Inflammation, Sorbonne Universités, UPMC Univ Paris 06, Université Pierre et Marie Curie, 4 Place Jussieu, 75252 Paris Cedex 05, France.

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http://dx.doi.org/10.1016/j.biochi.2013.12.005DOI Listing
May 2014

Proteome modulation in H9c2 cardiac cells by microRNAs miR-378 and miR-378.

Mol Cell Proteomics 2014 Jan 25;13(1):18-29. Epub 2013 Sep 25.

Team 1: Genetic and physiopathology of muscular tissues.

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http://dx.doi.org/10.1074/mcp.M113.030569DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3879613PMC
January 2014

Proteome alteration in oxidative stress-sensitive methionine sulfoxide reductase-silenced HEK293 cells.

Free Radic Biol Med 2013 Dec 27;65:1023-1036. Epub 2013 Aug 27.

Laboratoire de Biologie Cellulaire du Vieillissement, UR4, IFR83, Université Pierre et Marie Curie-Paris 6, 75005 Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.freeradbiomed.2013.08.008DOI Listing
December 2013

Differential expression and glycative damage affect specific mitochondrial proteins with aging in rat liver.

Biochim Biophys Acta 2013 Dec 30;1832(12):2057-67. Epub 2013 Jul 30.

Université Paris Diderot-Paris 7, Sorbonne Paris Cité, UFR SDV, 75205 Paris Cedex 13, France; Laboratoire de Biologie Cellulaire du Vieillissement, UR4-UPMC, IFR 83, Université Pierre et Marie Curie-Paris 6, 75252 Paris Cedex 05, France. Electronic address:

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http://ac.els-cdn.com/S0925443913002585/1-s2.0-S092544391300
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http://linkinghub.elsevier.com/retrieve/pii/S092544391300258
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http://dx.doi.org/10.1016/j.bbadis.2013.07.015DOI Listing
December 2013

Proteomic quantification and identification of carbonylated proteins upon oxidative stress and during cellular aging.

J Proteomics 2013 Oct 18;92:63-70. Epub 2013 May 18.

Laboratoire de Biologie Cellulaire du Vieillissement, UR4-IFR83, Université Pierre et Marie Curie-Paris 6, 4 place Jussieu, 75252 Paris Cedex 05, France.

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http://dx.doi.org/10.1016/j.jprot.2013.05.008DOI Listing
October 2013

Expression and modification proteomics during skeletal muscle ageing.

Biogerontology 2013 Jun 28;14(3):339-52. Epub 2013 Apr 28.

Laboratoire de Biologie Cellulaire du Vieillissement, UR4, UPMC Paris 6 University, 4 place Jussieu, 75252, Paris Cedex 05, France.

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http://dx.doi.org/10.1007/s10522-013-9426-7DOI Listing
June 2013

Deletion of the mitochondrial Pim1/Lon protease in yeast results in accelerated aging and impairment of the proteasome.

Free Radic Biol Med 2013 Mar 5;56:9-16. Epub 2012 Dec 5.

Department of Cell and Molecular Biology, Gothenburg University, Göteborg 41390, Sweden.

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http://dx.doi.org/10.1016/j.freeradbiomed.2012.11.019DOI Listing
March 2013

Oxidative proteome modifications target specific cellular pathways during oxidative stress, cellular senescence and aging.

Exp Gerontol 2013 Jul 2;48(7):620-5. Epub 2012 Nov 2.

Laboratoire de Biologie Cellulaire du Vieillissement, UR4-IFR83, Université Pierre et Marie Curie-Paris 6, 4 place Jussieu, 75252 Paris Cedex 05, France.

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https://linkinghub.elsevier.com/retrieve/pii/S05315565120029
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http://dx.doi.org/10.1016/j.exger.2012.10.007DOI Listing
July 2013

Protein oxidative damage at the crossroads of cellular senescence, aging, and age-related diseases.

Oxid Med Cell Longev 2012 17;2012:919832. Epub 2012 Oct 17.

Laboratoire de Biologie Cellulaire du Vieillissement, UR4-IFR83, Université Pierre et Marie Curie-Paris 6, 4 Place Jussieu, 75252 Paris Cedex 05, France.

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http://dx.doi.org/10.1155/2012/919832DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3483731PMC
April 2013

Protein damage, repair and proteolysis.

Mol Aspects Med 2014 Feb 26;35:1-71. Epub 2012 Oct 26.

Institute of Biology, Medicinal Chemistry and Biotechnology, National Helenic Research Foundation, 48 Vas. Constantinou Ave., 116 35 Athens, Greece. Electronic address:

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http://dx.doi.org/10.1016/j.mam.2012.09.001DOI Listing
February 2014

Clearance of genetic variants of amyloid β peptide by neuronal and non-neuronal cells.

Protein Pept Lett 2013 May;20(5):550-61

Laboratoire de Biochimie des Signaux Régulateurs Cellulaires et Moléculaires, FRE 2621 CNRS, Université Pierre et Marie Curie (Paris 6), Paris, France.

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http://dx.doi.org/10.2174/0929866511320050008DOI Listing
May 2013

Changes of the proteasomal system during the aging process.

Prog Mol Biol Transl Sci 2012 ;109:249-75

Laboratoire de Biologie Cellulaire du Vieillissement, UR4-IFR83, Université Pierre et Marie Curie–Paris 6, 4 place Jussieu, Paris Cedex 05, France.

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http://dx.doi.org/10.1016/B978-0-12-397863-9.00007-9DOI Listing
September 2013

Catalase, a target of glycation damage in rat liver mitochondria with aging.

Biochim Biophys Acta 2012 Oct 7;1822(10):1527-34. Epub 2012 Jun 7.

Laboratoire de Biologie et Biochimie Cellulaire du Vieillissement, Université Paris Diderot-Paris7, France.

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http://dx.doi.org/10.1016/j.bbadis.2012.05.016DOI Listing
October 2012

Photosensitized reactions mediated by the major chromophore arising from glucose decomposition, result in oxidation and cross-linking of lens proteins and activation of the proteasome.

Biochim Biophys Acta 2012 Apr 7;1822(4):564-72. Epub 2011 Dec 7.

Centro de Nutrición Molecular y Enfermedades Crónicas, Facultad de Ciencias Biológicas, Pontificia Universidad Católica de Chile, Santiago, Chile.

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http://dx.doi.org/10.1016/j.bbadis.2011.11.018DOI Listing
April 2012

Oxidative stress-induced proteome alterations target different cellular pathways in human myoblasts.

Free Radic Biol Med 2011 Oct 5;51(8):1522-32. Epub 2011 Jul 5.

Laboratoire de Biologie Cellulaire du Vieillissement, UR4, Université Pierre et Marie Curie-Paris 6, 75252 Paris Cedex 05, France.

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http://dx.doi.org/10.1016/j.freeradbiomed.2011.06.032DOI Listing
October 2011

Simultaneous chemical and photochemical protein crosslinking induced by irradiation of eye lens proteins in the presence of ascorbate: the photosensitizing role of an UVA-visible-absorbing decomposition product of vitamin C.

Photochem Photobiol Sci 2010 Oct 24;9(10):1351-8. Epub 2010 Aug 24.

Departamento de Química Física, Facultad de Química, Pontificia Universidad Católica de Chile, Casilla 306, Correo 22, Santiago de Chile.

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http://dx.doi.org/10.1039/c0pp00048eDOI Listing
October 2010

Dietary fatty acids and oxidative stress in the heart mitochondria.

Mitochondrion 2011 Jan 5;11(1):97-103. Epub 2010 Aug 5.

Laboratoire de Biologie Intégrative, Université du Québec, Rimouski, Québec, Canada.

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http://dx.doi.org/10.1016/j.mito.2010.07.014DOI Listing
January 2011

Identification of novel oxidized protein substrates and physiological partners of the mitochondrial ATP-dependent Lon-like protease Pim1.

J Biol Chem 2010 Apr 11;285(15):11445-57. Epub 2010 Feb 11.

Laboratoire de Biologie Cellulaire du Vieillissement, UR4, Vieillissement, Stress et Inflammation, Université Pierre et Marie Curie-Paris 6, Case Courrier 256, Batiment A, 5ème Etage, 7 Quai Saint Bernard, 75252 Paris Cedex 05, France.

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http://www.jbc.org/content/285/15/11445.full.pdf
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http://www.jbc.org/cgi/doi/10.1074/jbc.M109.065425
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http://dx.doi.org/10.1074/jbc.M109.065425DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2857023PMC
April 2010

Protein modification and replicative senescence of WI-38 human embryonic fibroblasts.

Aging Cell 2010 Apr 22;9(2):252-72. Epub 2010 Jan 22.

Université Pierre et Marie Curie-Paris, France.

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http://dx.doi.org/10.1111/j.1474-9726.2010.00555.xDOI Listing
April 2010

Oxidized mitochondrial protein degradation and repair in aging and oxidative stress.

Antioxid Redox Signal 2010 Aug;13(4):539-49

Laboratoire de Biologie Cellulaire du Vieillissement, Université Pierre et Marie Paris, France.

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http://www.liebertpub.com/doi/10.1089/ars.2009.2998
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http://dx.doi.org/10.1089/ars.2009.2998DOI Listing
August 2010

Impact of hydrogen peroxide on the activity, structure, and conformational stability of the oxidized protein repair enzyme methionine sulfoxide reductase A.

J Mol Biol 2009 Oct 30;393(1):58-66. Epub 2009 Jul 30.

Laboratoire de Biologie et Biochimie Cellulaire du Vieillissement, EA3106, Université Paris Diderot-Paris 7, France.

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http://dx.doi.org/10.1016/j.jmb.2009.07.072DOI Listing
October 2009

Repeated exposures to UVB induce differentiation rather than senescence of human keratinocytes lacking p16(INK-4A).

Biogerontology 2010 Apr 24;11(2):167-81. Epub 2009 Jun 24.

Research Unit of Cellular Biology, Department of Biology, University of Namur, Rue de Bruxelles 61, Namur, Belgium.

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http://dx.doi.org/10.1007/s10522-009-9238-yDOI Listing
April 2010

Frataxin deficiency causes upregulation of mitochondrial Lon and ClpP proteases and severe loss of mitochondrial Fe-S proteins.

FEBS J 2009 Feb 12;276(4):1036-47. Epub 2008 Jan 12.

Institut de Chimie des Substances Naturelles, Centre National de la Recherche Scientifique, Gif-sur-Yvette, France.

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http://dx.doi.org/10.1111/j.1742-4658.2008.06847.xDOI Listing
February 2009

Overexpression of methionine sulfoxide reductases A and B2 protects MOLT-4 cells against zinc-induced oxidative stress.

Antioxid Redox Signal 2009 Feb;11(2):215-25

Laboratoire de Biologie et Biochimie Cellulaire du vieillissement, Université Paris-Diderot-Paris, Paris, France.

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http://dx.doi.org/10.1089/ars.2008.2102DOI Listing
February 2009

Advanced glycation endproducts induce photocrosslinking and oxidation of bovine lens proteins through type-I mechanism.

Photochem Photobiol 2009 Jan-Feb;85(1):185-94. Epub 2008 Jul 30.

Laboratorio de Química Biológica, Departamento de Química Física, Facultad de Química, Pontificia Universidad Católica de Chile, Santiago, Chile.

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http://dx.doi.org/10.1111/j.1751-1097.2008.00415.xDOI Listing
April 2009

Autosensitized oxidation of glycated bovine lens proteins irradiated with UVA-visible light at low oxygen concentration.

Photochem Photobiol Sci 2008 Jun 28;7(6):718-24. Epub 2008 Mar 28.

Departamento de Química Física, Facultad de Química, Pontificia Universidad Católica de Chile, Casilla 306, Correo 22, Santiago, Chile.

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http://dx.doi.org/10.1039/b719167gDOI Listing
June 2008

Mitochondrial protein quality control: implications in ageing.

Biotechnol J 2008 Jun;3(6):757-64

Laboratoire de Biologie et Biochimie Cellulaire du Vieillissement, EA 3106, Université Paris 7-Denis Diderot, Paris, France.

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http://dx.doi.org/10.1002/biot.200800041DOI Listing
June 2008

Overexpression of mitochondrial methionine sulfoxide reductase B2 protects leukemia cells from oxidative stress-induced cell death and protein damage.

J Biol Chem 2008 Jun 17;283(24):16673-81. Epub 2008 Apr 17.

Laboratoire de Biologie et Biochimie Cellulaire du Vieillissement, EA 3106, Université Paris Diderot-Paris 7, 2 Place Jussieu, 75251 Paris Cedex 05, France.

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http://dx.doi.org/10.1074/jbc.M708580200DOI Listing
June 2008

Protein oxidative modifications and replicative senescence of WI-38 human embryonic fibroblasts.

Ann N Y Acad Sci 2007 Nov;1119:88-96

Laboratoire de Biologie et Biochimie Cellulaire du Vieillissement, Université Paris 7-Denis Diderot, 75251, Paris Cedex 05, France.

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http://doi.wiley.com/10.1196/annals.1404.020
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http://dx.doi.org/10.1196/annals.1404.020DOI Listing
November 2007

Zinc supplementation in the elderly subjects: effect on oxidized protein degradation and repair systems in peripheral blood lymphocytes.

Exp Gerontol 2008 May 25;43(5):483-7. Epub 2007 Oct 25.

Laboratoire de Biologie et Biochimie Cellulaire du Vieillissement, EA 3106/IFR 117, Université Paris 7-Denis Diderot, Paris cedex 05, France.

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http://dx.doi.org/10.1016/j.exger.2007.10.007DOI Listing
May 2008

Towards the control of intracellular protein turnover: mitochondrial Lon protease inhibitors versus proteasome inhibitors.

Biochimie 2008 Feb 25;90(2):260-9. Epub 2007 Oct 25.

Laboratoire de Biologie et Biochimie Cellulaire du Vieillissement, EA 3106 / IFR 117, Université Paris 7-Denis Diderot, 2 place Jussieu, Tour 33-23, 1(er) étage, CC 7128, 75251 Paris cedex 05, France.

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http://dx.doi.org/10.1016/j.biochi.2007.10.010DOI Listing
February 2008

Glycation damage targets glutamate dehydrogenase in the rat liver mitochondrial matrix during aging.

FEBS J 2007 Nov 19;274(22):5949-61. Epub 2007 Oct 19.

Laboratoire de Biologie et Biochimie Cellulaire du Vieillissement, Université Paris 7-Denis Diderot, France.

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http://dx.doi.org/10.1111/j.1742-4658.2007.06118.xDOI Listing
November 2007

Proteasome and photoaging: the effects of UV irradiation.

Ann N Y Acad Sci 2007 Apr;1100:280-90

Laboratoire de Biologie et Biochimie Cellulaire du Vieillissement, Université Paris 7-Denis Diderot, 2 Place Jussieu, 75251, Paris Cedex 05, France.

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http://dx.doi.org/10.1196/annals.1395.029DOI Listing
April 2007

Impairment of methionine sulfoxide reductase during UV irradiation and photoaging.

Exp Gerontol 2007 Sep 21;42(9):859-63. Epub 2007 Feb 21.

Laboratoire de Biologie et Biochimie Cellulaire du Vieillissement, EA 3106/IFR 117, Université Paris 7-Denis Diderot, 2 place Jussieu, Tour 33-23, 1er étage, CC 7128, 75251 Paris cedex 05, France.

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http://dx.doi.org/10.1016/j.exger.2007.02.006DOI Listing
September 2007

Endogenous C-terminal fragments of beta-amyloid precursor protein from Xenopus laevis skin exudate.

Comp Biochem Physiol B Biochem Mol Biol 2007 Apr 12;146(4):530-9. Epub 2006 Dec 12.

Laboratoire de Biochimie des Signaux Régulateurs Cellulaires and Moléculaires, Université Pierre et Marie Curie-Paris6, FRE 2621 CNRS, 96 Bd Raspail, Paris, F-75006 France.

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http://dx.doi.org/10.1016/j.cbpb.2006.11.027DOI Listing
April 2007

Maintenance of proteins and aging: the role of oxidized protein repair.

Free Radic Res 2006 Dec;40(12):1269-76

Laboratoire de Biologie et Biochimie Cellulaire du Vieillissement, EA 3106/IFR 117, Université Denis Diderot-Paris 7, CC 7128, 2 Place Jussieu, Paris Cedex, France.

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http://dx.doi.org/10.1080/10715760600917144DOI Listing
December 2006

Methionine sulfoxide reductases: relevance to aging and protection against oxidative stress.

Ann N Y Acad Sci 2006 May;1067:37-44

Laboratoire de Biologie et Biochimie Cellulaire du Vieillissement, Université Paris 7-Denis Diderot, France.

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http://dx.doi.org/10.1196/annals.1354.006DOI Listing
May 2006

Mitochondrial protein oxidation and degradation in response to oxidative stress and aging.

Exp Gerontol 2006 Jul 4;41(7):653-7. Epub 2006 May 4.

Université Denis Diderot-Paris 7, Laboratoire de Biologie et Biochimie Cellulaire du Vieillissement, EA 3106/IFR 117, case courrier 7128, 2 Place Jussieu, 75251 Paris Cedex 05, France.

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http://dx.doi.org/10.1016/j.exger.2006.03.013DOI Listing
July 2006

Alterations in mitochondrial and cytosolic methionine sulfoxide reductase activity during cardiac ischemia and reperfusion.

Exp Gerontol 2006 Jul 4;41(7):663-7. Epub 2006 May 4.

Laboratoire de Biologie et Biochimie Cellulaire du Vieillissement, EA 3106/IFR 117, Université Paris 7-Denis Diderot, 2 place Jussieu, Tour 33-23, 1er étage, CC 7128, 75251 Paris Cedex 05, France.

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http://linkinghub.elsevier.com/retrieve/pii/S053155650600077
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http://dx.doi.org/10.1016/j.exger.2006.03.011DOI Listing
July 2006

Oxidized protein degradation and repair in ageing and oxidative stress.

Authors:
Bertrand Friguet

FEBS Lett 2006 May 20;580(12):2910-6. Epub 2006 Mar 20.

Laboratoire de Biologie et Biochimie Cellulaire du Vieillissement (EA 3106/IFR 117), Université Denis Diderot, Paris 7, 2 Place Jussieu, 75005 Paris, France.

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http://dx.doi.org/10.1016/j.febslet.2006.03.028DOI Listing
May 2006

Inactivation of the proteasome by 4-hydroxy-2-nonenal is site specific and dependant on 20S proteasome subtypes.

Arch Biochem Biophys 2006 Sep 24;453(1):135-42. Epub 2006 Feb 24.

Laboratoire de Biologie et Biochimie Cellulaire du Vieillissement, EA 3106, IFR 117, Université Paris 7 - Denis Diderot, 2 place Jussieu, 75251 Paris cedex 05, France.

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http://dx.doi.org/10.1016/j.abb.2006.02.003DOI Listing
September 2006

Proteasome function in aging and oxidative stress: implications in protein maintenance failure.

Antioxid Redox Signal 2006 Jan-Feb;8(1-2):205-16

Laboratoire de Biologie et Biochimie Cellulaire du Vieillissement, Université Denis Diderot-Paris 7, Paris, France.

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http://dx.doi.org/10.1089/ars.2006.8.205DOI Listing
May 2006

Algae extract-mediated stimulation and protection of proteasome activity within human keratinocytes exposed to UVA and UVB irradiation.

Antioxid Redox Signal 2006 Jan-Feb;8(1-2):136-43

Laboratoire de Biologie et Biochimie Cellulaire du Vieillissement, Université Paris 7-Denis Diderot, Paris, France.

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http://dx.doi.org/10.1089/ars.2006.8.136DOI Listing
May 2006

The ubiquitin-proteasome system at the crossroads of stress-response and ageing pathways: a handle for skin care?

Ageing Res Rev 2006 Feb 5;5(1):60-90. Epub 2005 Dec 5.

Laboratoire de Biologie et Biochimie Cellulaire du Vieillissement, Université Denis Diderot-Paris 7, C.C.7128, 2 Place Jussieu, 75251 Paris Cédex 05, France.

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http://dx.doi.org/10.1016/j.arr.2005.09.002DOI Listing
February 2006

Overexpression of MsrA protects WI-38 SV40 human fibroblasts against H2O2-mediated oxidative stress.

Free Radic Biol Med 2005 Nov 23;39(10):1332-41. Epub 2005 Sep 23.

Laboratoire de Biologie et Biochimie Cellulaire du Vieillissement, Université Paris 7-Denis Diderot, 2 Place Jussieu, Tower 33-23, First Floor, CC 7128, 75251 Paris Cedex 05, France.

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http://dx.doi.org/10.1016/j.freeradbiomed.2005.06.017DOI Listing
November 2005

Oxidized SOD1 alters proteasome activities in vitro and in the cortex of SOD1 overexpressing mice.

FEBS Lett 2005 Jul;579(17):3613-8

EA3508, Modèles de dérégulation génique: Trisomie 21 et Hyperhomocysteinémie. Université Paris 7, Denis Diderot, Campus Jussieu, Tour 54, 2 étage, couloir 54/53, Case 7104, 2, place Jussieu, 75005 Paris, France.

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http://dx.doi.org/10.1016/j.febslet.2005.05.048DOI Listing
July 2005

Protein maintenance in aging and replicative senescence: a role for the peptide methionine sulfoxide reductases.

Biochim Biophys Acta 2005 Jan;1703(2):261-6

Laboratoire de Biologie et Biochimie Cellulaire du Vieillissement, EA 3106, IFR 117, Université Denis Diderot-Paris 7, CC 7128, 2 Place Jussieu, 75251 Paris Cedex 05, France.

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http://dx.doi.org/10.1016/j.bbapap.2004.08.018DOI Listing
January 2005

Are expanded polyglutamine proteins a proteasome substrate?

Rejuvenation Res 2004 ;7(4):239-42

Laboratoire de Biologie et Biochimie Cellulaire du Vieillissement, Université Paris 7--Denis Diderot, Paris, France.

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http://dx.doi.org/10.1089/rej.2004.7.239DOI Listing
February 2005

Repeated exposure of human skin fibroblasts to UVB at subcytotoxic level triggers premature senescence through the TGF-beta1 signaling pathway.

J Cell Sci 2005 Feb 25;118(Pt 4):743-58. Epub 2005 Jan 25.

Laboratory of Biochemistry and Cellular Biology, Department of Biology, University of Namur (FUNDP), Rue de Bruxelles, 61, 5000 Namur, Belgium.

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http://dx.doi.org/10.1242/jcs.01651DOI Listing
February 2005

Age-related impairment of mitochondrial matrix aconitase and ATP-stimulated protease in rat liver and heart.

Eur J Biochem 2004 Nov;271(22):4559-64

Laboratoire de Biologie et Biochimie Cellulaire du Vieillissement, Université Paris 7-Denis Diderot, Paris, France.

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http://doi.wiley.com/10.1111/j.1432-1033.2004.04422.x
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http://dx.doi.org/10.1111/j.1432-1033.2004.04422.xDOI Listing
November 2004

Enzymatic reactions involved in the repair of oxidized proteins.

Exp Gerontol 2004 Aug;39(8):1117-23

Laboratoire de Biologie et Biochimie Cellulaire du Vieillissement, Université denis Diderot, Paris 7, France.

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http://dx.doi.org/10.1016/j.exger.2004.06.008DOI Listing
August 2004

Algae extract protection effect on oxidized protein level in human stratum corneum.

Ann N Y Acad Sci 2004 Jun;1019:219-22

LVMH Branche Parfums et Cosmetiques, 45804, Saint Jean de Braye, Cedex, France.

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http://dx.doi.org/10.1196/annals.1297.036DOI Listing
June 2004

Evidence of preferential protein targets for age-related modifications in peripheral blood lymphocytes.

Ann N Y Acad Sci 2004 Jun;1019:211-4

Laboratoire de Biologie et Biochimie Cellulaire du Vieillissement, IFR 117, Université Paris 7-Denis Diderot, Paris, France.

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http://dx.doi.org/10.1196/annals.1297.034DOI Listing
June 2004

Age-dependent protein modifications and declining proteasome activity in the human lens.

Arch Biochem Biophys 2004 Jul;427(2):197-203

Laboratorio de Química Biológica, Facultad de Química, Pontificia Universidad Católica de Chile, Av. Vicuña Mackenna 4860, Comuna Macul, Santiago, Chile.

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http://dx.doi.org/10.1016/j.abb.2004.05.006DOI Listing
July 2004

Essential role of methionine residues in calmodulin binding to Bordetella pertussis adenylate cyclase, as probed by selective oxidation and repair by the peptide methionine sulfoxide reductases.

J Biol Chem 2004 Jul 17;279(29):30210-8. Epub 2004 May 17.

Laboratoire de Biologie et Biochimie Cellulaire du Vieillissement, EA 3106, IFR 117, Université Paris 7, Denis Diderot, 2 place Jussieu, Paris 75005, France.

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http://dx.doi.org/10.1074/jbc.M400604200DOI Listing
July 2004