Bertrand Cariou

Bertrand Cariou

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Bertrand Cariou

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EGF-A peptides: A promising strategy for PCSK9 inhibition.

Atherosclerosis 2019 Nov 19. Epub 2019 Nov 19.

L'institut du thorax, INSERM, CNRS, UNIV Nantes, CHU Nantes, Nantes, France.

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http://dx.doi.org/10.1016/j.atherosclerosis.2019.11.010DOI Listing
November 2019

Bile acids associate with glucose metabolism, but do not predict conversion from impaired fasting glucose to diabetes.

Metabolism 2019 Nov 27:154042. Epub 2019 Nov 27.

L'institut du thorax, Department of Endocrinology, CIC 1413 INSERM, CHU Nantes, Nantes, France; L'institut du thorax, INSERM, CNRS, Univ. Nantes, CHU Nantes, Nantes, France. Electronic address:

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http://dx.doi.org/10.1016/j.metabol.2019.154042DOI Listing
November 2019

Phenome-wide association analysis of LDL-cholesterol lowering genetic variants in PCSK9.

Authors:
Amand F Schmidt Michael V Holmes David Preiss Daniel I Swerdlow Spiros Denaxas Ghazaleh Fatemifar Rupert Faraway Chris Finan Dennis Valentine Zammy Fairhurst-Hunter Fernando Pires Hartwig Bernardo Lessa Horta Elina Hypponen Christine Power Max Moldovan Erik van Iperen Kees Hovingh Ilja Demuth Kristina Norman Elisabeth Steinhagen-Thiessen Juri Demuth Lars Bertram Christina M Lill Stefan Coassin Johann Willeit Stefan Kiechl Karin Willeit Dan Mason John Wright Richard Morris Goya Wanamethee Peter Whincup Yoav Ben-Shlomo Stela McLachlan Jackie F Price Mika Kivimaki Catherine Welch Adelaida Sanchez-Galvez Pedro Marques-Vidal Andrew Nicolaides Andrie G Panayiotou N Charlotte Onland-Moret Yvonne T van der Schouw Giuseppe Matullo Giovanni Fiorito Simonetta Guarrera Carlotta Sacerdote Nicholas J Wareham Claudia Langenberg Robert A Scott Jian'an Luan Martin Bobak Sofia Malyutina Andrzej Pająk Ruzena Kubinova Abdonas Tamosiunas Hynek Pikhart Niels Grarup Oluf Pedersen Torben Hansen Allan Linneberg Tine Jess Jackie Cooper Steve E Humphries Murray Brilliant Terrie Kitchner Hakon Hakonarson David S Carrell Catherine A McCarty Kirchner H Lester Eric B Larson David R Crosslin Mariza de Andrade Dan M Roden Joshua C Denny Cara Carty Stephen Hancock John Attia Elizabeth Holliday Rodney Scott Peter Schofield Martin O'Donnell Salim Yusuf Michael Chong Guillaume Pare Pim van der Harst M Abdullah Said Ruben N Eppinga Niek Verweij Harold Snieder Tim Christen D O Mook-Kanamori Stefan Gustafsson Lars Lind Erik Ingelsson Raha Pazoki Oscar Franco Albert Hofman Andre Uitterlinden Abbas Dehghan Alexander Teumer Sebastian Baumeister Marcus Dörr Markus M Lerch Uwe Völker Henry Völzke Joey Ward Jill P Pell Tom Meade Ingrid E Christophersen Anke H Maitland-van der Zee Ekaterina V Baranova Robin Young Ian Ford Archie Campbell Sandosh Padmanabhan Michiel L Bots Diederick E Grobbee Philippe Froguel Dorothée Thuillier Ronan Roussel Amélie Bonnefond Bertrand Cariou Melissa Smart Yanchun Bao Meena Kumari Anubha Mahajan Jemma C Hopewell Sudha Seshadri Caroline Dale Rui Providencia E Costa Paul M Ridker Daniel I Chasman Alex P Reiner Marylyn D Ritchie Leslie A Lange Alex J Cornish Sara E Dobbins Kari Hemminki Ben Kinnersley Marc Sanson Karim Labreche Matthias Simon Melissa Bondy Philip Law Helen Speedy James Allan Ni Li Molly Went Niels Weinhold Gareth Morgan Pieter Sonneveld Björn Nilsson Hartmut Goldschmidt Amit Sud Andreas Engert Markus Hansson Harry Hemingway Folkert W Asselbergs Riyaz S Patel Brendan J Keating Naveed Sattar Richard Houlston Juan P Casas Aroon D Hingorani

BMC Cardiovasc Disord 2019 Oct 29;19(1):240. Epub 2019 Oct 29.

Institute of Cardiovascular Science, University College London, 222 Euston Road, London, NW1 2DA, UK.

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http://dx.doi.org/10.1186/s12872-019-1187-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6820948PMC
October 2019

Efficacy and safety of proprotein convertase subtilisin/kexin 9 inhibitors in people with diabetes and dyslipidaemia.

Diabetes Obes Metab 2019 Apr;21 Suppl 1:39-51

L'institut du thorax, INSERM, CNRS, University of Nantes, CHU Nantes, Nantes, France.

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http://dx.doi.org/10.1111/dom.13636DOI Listing
April 2019

Changes in metabolic parameters and cardiovascular risk factors after therapeutic control of acromegaly vary with the treatment modality. Data from the Bicêtre cohort, and review of the literature.

Endocrine 2019 02 5;63(2):348-360. Epub 2018 Nov 5.

Assistance Publique-Hôpitaux de Paris, Hôpital de Bicêtre, Service d'Endocrinologie et des Maladies de la Reproduction, Centre de Référence des Maladies Rares de l'Hypophyse, F-94275, Le Kremlin Bicêtre, France.

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http://link.springer.com/10.1007/s12020-018-1797-8
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http://dx.doi.org/10.1007/s12020-018-1797-8DOI Listing
February 2019

[At the heart of diabetic cardiomyopathy: Bscl2 knockout mice to investigate glucotoxicity].

Med Sci (Paris) 2018 Jun-Jul;34(6-7):563-570. Epub 2018 Jul 31.

Institut du thorax, Inserm, CNRS, univ Nantes, Nantes, F-44000, France.

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http://dx.doi.org/10.1051/medsci/20183406016DOI Listing
January 2019

Severely uncontrolled diabetes: a new aetiology of acquired bisalbuminaemia.

Diabetes Metab 2019 Jan 17. Epub 2019 Jan 17.

L'institut du thorax, Department of Endocrinology, CHU de Nantes, 44000 Nantes, France.

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http://dx.doi.org/10.1016/j.diabet.2019.01.004DOI Listing
January 2019

Inhibiting PCSK9 - biology beyond LDL control.

Nat Rev Endocrinol 2018 12;15(1):52-62

Department of Vascular Medicine, Academisch Medisch Centrum, Amsterdam, Netherlands.

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http://www.nature.com/articles/s41574-018-0110-5
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http://dx.doi.org/10.1038/s41574-018-0110-5DOI Listing
December 2018

Circulating PCSK9 levels are not associated with the severity of hepatic steatosis and NASH in a high-risk population.

Atherosclerosis 2018 11 13;278:82-90. Epub 2018 Sep 13.

L'institut du thorax, Department of Endocrinology, CIC 1413 INSERM, CHU Nantes, Nantes, France; L'institut du thorax, INSERM, CNRS, CHU Nantes, Nantes, France. Electronic address:

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http://dx.doi.org/10.1016/j.atherosclerosis.2018.09.008DOI Listing
November 2018

Expert opinion on immunotherapy induced diabetes.

Ann Endocrinol (Paris) 2018 Oct 25;79(5):545-549. Epub 2018 Jul 25.

Department of endocrinology, l'institut du thorax, CHU Nantes, 44000 Nantes, France.

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https://linkinghub.elsevier.com/retrieve/pii/S00034266183118
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http://dx.doi.org/10.1016/j.ando.2018.07.006DOI Listing
October 2018

Expert opinion on the metabolic complications of mTOR inhibitors.

Ann Endocrinol (Paris) 2018 Oct 23;79(5):583-590. Epub 2018 Aug 23.

Service d'endocrinologie, diabétologie, maladies métaboliques, CHU de Dijon, 2, boulevard du Maréchal-de-Lattre, BP 77908, 21000 Dijon, France; Unité Inserm, LNC-UMR 1231, université de Bourgogne, Dijon, France.

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http://dx.doi.org/10.1016/j.ando.2018.07.010DOI Listing
October 2018

Expert opinion on the metabolic complications of new anticancer therapies: Tyrosine kinase inhibitors.

Ann Endocrinol (Paris) 2018 Oct 1;79(5):574-582. Epub 2018 Aug 1.

CHU Dijon, service d'endocrinologie, diabétologie, maladies métaboliques, hôpital François-Mitterrand, 21034 Dijon cedex, France.

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https://linkinghub.elsevier.com/retrieve/pii/S00034266183120
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http://dx.doi.org/10.1016/j.ando.2018.07.011DOI Listing
October 2018

High burden of recurrent cardiovascular events in heterozygous familial hypercholesterolemia: The French Familial Hypercholesterolemia Registry.

Atherosclerosis 2018 10;277:334-340

Department of Endocrinology and Cardiovascular Disease Prevention, Institute of Cardio Metabolism and Nutrition (ICAN), La Pitié-Salpêtrière Hospital, AP-HP, Paris, France.

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http://dx.doi.org/10.1016/j.atherosclerosis.2018.08.010DOI Listing
October 2018

Chronic O-GlcNAcylation and Diabetic Cardiomyopathy: The Bitterness of Glucose.

Front Endocrinol (Lausanne) 2018 29;9:642. Epub 2018 Oct 29.

l'institut du thorax, INSERM, CNRS, UNIV Nantes, Nantes, France.

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https://www.frontiersin.org/article/10.3389/fendo.2018.00642
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http://dx.doi.org/10.3389/fendo.2018.00642DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6215811PMC
October 2018

Semaglutide as a therapeutic option for elderly patients with type 2 diabetes: Pooled analysis of the SUSTAIN 1-5 trials.

Diabetes Obes Metab 2018 09 7;20(9):2291-2297. Epub 2018 Jun 7.

L'Institut du Thorax, Department of Endocrinology, CHU de Nantes, Nantes, France.

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http://dx.doi.org/10.1111/dom.13331DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6099273PMC
September 2018

[Familial hypercholesterolemia: An under-diagnosed and under-treated disease. Survey of 495 physicians].

Presse Med 2018 Sep 27;47(9):e159-e167. Epub 2018 Jul 27.

Hôpital Pitié-Salpêtrière, endocrinologie, métabolisme et prévention des maladies cardiovasculaires, 75013 Paris, France.

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https://linkinghub.elsevier.com/retrieve/pii/S07554982183027
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http://dx.doi.org/10.1016/j.lpm.2018.01.025DOI Listing
September 2018

Poststatin era in atherosclerosis management: lessons from epidemiologic and genetic studies.

Curr Opin Lipidol 2018 06;29(3):246-258

L'institut du thorax, INSERM, CNRS, UNIV Nantes, CHU Nantes, Nantes, France.

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http://dx.doi.org/10.1097/MOL.0000000000000505DOI Listing
June 2018

Beyond LDL: What Role for PCSK9 in Triglyceride-Rich Lipoprotein Metabolism?

Trends Endocrinol Metab 2018 06 14;29(6):420-434. Epub 2018 Apr 14.

L'institut du thorax, INSERM, CNRS, Université de Nantes, Nantes, France; L'institut du thorax, Department of Endocrinology, CHU NANTES, Nantes, France. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10432760183005
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http://dx.doi.org/10.1016/j.tem.2018.03.013DOI Listing
June 2018

Homozygous Familial Hypercholesterolemia Patients With Identical Mutations Variably Express the LDLR (Low-Density Lipoprotein Receptor): Implications for the Efficacy of Evolocumab.

Arterioscler Thromb Vasc Biol 2018 03 28;38(3):592-598. Epub 2017 Dec 28.

From the CRNH Ouest, INRA UMR 1280 PhAN (A.T., V.B., M.C., G.L.) and L'institut du thorax, INSERM UMR 1087, CNRS UMR 6291 (A.T., M.P., B.C.), Université de Nantes, France; L'institut du thorax, CHU de Nantes, CIC Endocrino-Nutrition, France (A.T., M.P., B.C.); Lipidology Division of Internal Medicine, University of Cape Town, South Africa (D.J.B.); INSERM UMR 1188 DéTROI, Université de La Réunion, Sainte Clotilde, France (S.R.-M., V.B., K.C., B.N., S.B., G.L.); Amgen, Thousand Oaks, CA (L.T.); CHU Dijon Bourgogne, Point Médical, France (M.F.); and Faculty of Health Sciences, University of Witwatersrand, Johannesburg, South Africa (F.J.R.).

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http://dx.doi.org/10.1161/ATVBAHA.117.310217DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823753PMC
March 2018

Efficacy and safety of alirocumab in insulin-treated individuals with type 1 or type 2 diabetes and high cardiovascular risk: The ODYSSEY DM-INSULIN randomized trial.

Diabetes Obes Metab 2017 12 10;19(12):1781-1792. Epub 2017 Oct 10.

University of California San Diego School of Medicine, and Center for Metabolic Research, Veterans Affairs, San Diego Healthcare System, San Diego, California.

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http://dx.doi.org/10.1111/dom.13114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698740PMC
December 2017

Impact of protease inhibitors on circulating PCSK9 levels in HIV-infected antiretroviral-naive patients from an ongoing prospective cohort.

AIDS 2017 11;31(17):2367-2376

aAP-HP, Hôpital Saint-Antoine, Service de cardiologie bSorbonne-Universités, UPMC université Paris 06, Faculté de médecine cINSERM, Saint-Antoine Research Center, UMR S 938, Medical Faculty of Saint Antoine, Paris dInserm UMRS1018, CESP, HIV and Pediatry eParis-Sud University fDepartment of Public Health, Bicêtre Hospital, APHP gDepartment of Internal Medicine, Bicêtre Hospital, AP-HP, Le Kremlin-Bicêtre hl'institut du thorax, INSERM, CNRS, UNIV Nantes, Nantes iAP-HP, Hôpital Saint-Antoine, Laboratoire Commun de Biologie et Génétique Moléculaires et Endocrinologie jAssistance Publique des Hôpitaux de Paris, Hôpital Tenon, UF Bio-marqueurs Inflammatoires et métaboliques, Service de Biochimie, Paris kl'institut du thorax, CHU Nantes, Service de endocrinologie-maladies métaboliques et nutrition, Nantes, France.

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http://Insights.ovid.com/crossref?an=00002030-201711130-0000
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http://dx.doi.org/10.1097/QAD.0000000000001633DOI Listing
November 2017

Severe decrease in high-density lipoprotein cholesterol with the combination of fibrates and ezetimibe: A case series.

J Clin Lipidol 2017 Jan - Feb;11(1):289-293. Epub 2016 Nov 2.

Department of Endocrinology, Metabolic diseases and Nutrition, l'institut du thorax, CHU de Nantes, Nantes, France; CRNH, Human Nutrition Research Center, CHU, Nantes, France; INRA, UMR 1280, Physiologie des Adaptations Nutritionnelles, CHU Hôtel-Dieu, Nantes, France.

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http://dx.doi.org/10.1016/j.jacl.2016.10.012DOI Listing
October 2017

34 Congrès SFE Poitiers 2017.

Ann Endocrinol (Paris) 2017 Sep 12;78(4):199. Epub 2017 Aug 12.

Service d'endocrinologie, maladies métaboliques et nutrition, Pôle cardiovasculaire et métabolique, CHU Larrey, Toulouse, France.

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http://dx.doi.org/10.1016/j.ando.2017.07.736DOI Listing
September 2017

Glycaemic control influences the relationship between plasma PCSK9 and LDL cholesterol in type 1 diabetes.

Diabetes Obes Metab 2017 03 8;19(3):448-451. Epub 2016 Dec 8.

Department of Endocrinology, l'Institut du Thorax, INSERM, CNRS, CHU Nantes, Nantes University, Nantes, France.

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http://dx.doi.org/10.1111/dom.12819DOI Listing
March 2017

PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study.

Authors:
Amand F Schmidt Daniel I Swerdlow Michael V Holmes Riyaz S Patel Zammy Fairhurst-Hunter Donald M Lyall Fernando Pires Hartwig Bernardo Lessa Horta Elina Hyppönen Christine Power Max Moldovan Erik van Iperen G Kees Hovingh Ilja Demuth Kristina Norman Elisabeth Steinhagen-Thiessen Juri Demuth Lars Bertram Tian Liu Stefan Coassin Johann Willeit Stefan Kiechl Karin Willeit Dan Mason John Wright Richard Morris Goya Wanamethee Peter Whincup Yoav Ben-Shlomo Stela McLachlan Jackie F Price Mika Kivimaki Catherine Welch Adelaida Sanchez-Galvez Pedro Marques-Vidal Andrew Nicolaides Andrie G Panayiotou N Charlotte Onland-Moret Yvonne T van der Schouw Giuseppe Matullo Giovanni Fiorito Simonetta Guarrera Carlotta Sacerdote Nicholas J Wareham Claudia Langenberg Robert Scott Jian'an Luan Martin Bobak Sofia Malyutina Andrzej Pająk Ruzena Kubinova Abdonas Tamosiunas Hynek Pikhart Lise Lotte Nystrup Husemoen Niels Grarup Oluf Pedersen Torben Hansen Allan Linneberg Kenneth Starup Simonsen Jackie Cooper Steve E Humphries Murray Brilliant Terrie Kitchner Hakon Hakonarson David S Carrell Catherine A McCarty H Lester Kirchner Eric B Larson David R Crosslin Mariza de Andrade Dan M Roden Joshua C Denny Cara Carty Stephen Hancock John Attia Elizabeth Holliday Martin O'Donnell Salim Yusuf Michael Chong Guillaume Pare Pim van der Harst M Abdullah Said Ruben N Eppinga Niek Verweij Harold Snieder Tim Christen Dennis O Mook-Kanamori Stefan Gustafsson Lars Lind Erik Ingelsson Raha Pazoki Oscar Franco Albert Hofman Andre Uitterlinden Abbas Dehghan Alexander Teumer Sebastian Baumeister Marcus Dörr Markus M Lerch Uwe Völker Henry Völzke Joey Ward Jill P Pell Daniel J Smith Tom Meade Anke H Maitland-van der Zee Ekaterina V Baranova Robin Young Ian Ford Archie Campbell Sandosh Padmanabhan Michiel L Bots Diederick E Grobbee Philippe Froguel Dorothée Thuillier Beverley Balkau Amélie Bonnefond Bertrand Cariou Melissa Smart Yanchun Bao Meena Kumari Anubha Mahajan Paul M Ridker Daniel I Chasman Alex P Reiner Leslie A Lange Marylyn D Ritchie Folkert W Asselbergs Juan-Pablo Casas Brendan J Keating David Preiss Aroon D Hingorani Naveed Sattar

Lancet Diabetes Endocrinol 2017 02 29;5(2):97-105. Epub 2016 Nov 29.

Institute of Cardiovascular and Medical Sciences, University of Glasgow, Glasgow, UK. Electronic address:

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http://dx.doi.org/10.1016/S2213-8587(16)30396-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5266795PMC
February 2017

FGF21 Improves the Adipocyte Dysfunction Related to Seipin Deficiency.

Diabetes 2016 Nov 23;65(11):3410-3417. Epub 2016 Aug 23.

INSERM UMR S1087/CNRS UMR 6291, l'Institut du Thorax, Université de Nantes, Nantes, France

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http://dx.doi.org/10.2337/db16-0327DOI Listing
November 2016

Efficacy of alirocumab in high cardiovascular risk populations with or without heterozygous familial hypercholesterolemia: Pooled analysis of eight ODYSSEY Phase 3 clinical program trials.

Int J Cardiol 2016 Nov 18;223:750-757. Epub 2016 Aug 18.

Department of Endocrinology, l'Institut du Thorax, Nantes University Hospital, Nantes, France.

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http://dx.doi.org/10.1016/j.ijcard.2016.08.273DOI Listing
November 2016

PCSK9 and atherosclerosis: Beyond LDL-cholesterol lowering.

Atherosclerosis 2016 10 20;253:275-277. Epub 2016 Aug 20.

Central Arkansas Veterans Helthcare System, University of Arkansas for Medical Sciences, Little Rock, AR, USA. Electronic address:

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http://dx.doi.org/10.1016/j.atherosclerosis.2016.08.007DOI Listing
October 2016

Once-Daily Liraglutide Versus Lixisenatide as Add-on to Metformin in Type 2 Diabetes: A 26-Week Randomized Controlled Clinical Trial.

Diabetes Care 2016 Sep 16;39(9):1501-9. Epub 2016 Jun 16.

Department of Endocrinology, l'Institut du Thorax, Nantes University Hospital, Nantes, France.

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http://dx.doi.org/10.2337/dc15-2479DOI Listing
September 2016

[Management of dyslipidemia in adult].

Rev Prat 2016 Sep;66(7):727-41

Fédération d'endocrinologie, hôpital cardiovasculaire Louis-Pradel, groupe hospitalier Est, 69003 Lyon, France.

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September 2016

Sotagliflozin as a potential treatment for type 2 diabetes mellitus.

Expert Opin Investig Drugs 2015 7;24(12):1647-56. Epub 2015 Nov 7.

c Faculté de Médecine , Université de Nantes , Nantes F-44000 , France.

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http://dx.doi.org/10.1517/13543784.2015.1100361DOI Listing
July 2016

Identification of novel APOB mutations by targeted next-generation sequencing for the molecular diagnosis of familial hypobetalipoproteinemia.

Atherosclerosis 2016 07 11;250:52-6. Epub 2016 Apr 11.

INSERM, UMR1087, l'institut du thorax, Nantes, F-44000, France; CNRS, UMR 6291, Nantes, F-44000, France; Université de Nantes, Nantes, F-44000, France; CHU Nantes, l'institut du Thorax, Nantes, F-44000, France; CIC Thorax, CHU Nantes, l'institut du Thorax, Nantes, F-44000, France. Electronic address:

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http://dx.doi.org/10.1016/j.atherosclerosis.2016.04.010DOI Listing
July 2016

[Dyslipidemia and statins role]

Authors:
Bertrand Cariou

Rev Prat 2016 03;66(3):315-316

Clinique d'endocrinologie, CHU de Nantes, Nantes, France.

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March 2016

[LDL-cholesterol hypothesis:the lower is trully better]

Rev Prat 2016 03;66(3):317-321

Clinique d'endocrinologie.

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March 2016

[Adverse effects of statins]

Authors:
Bertrand Cariou

Rev Prat 2016 03;66(3):327-328

Clinique d'endocrinologie, Inserm UMR 1087-CNRS UMR 6291, institut du thorax, CHU de Nantes, Nantes, France.

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March 2016

[What is the place of statins in the treatment of diabetes?]

Authors:
Bertrand Cariou

Rev Prat 2016 03;66(3):328-329

Clinique d'endocrinologie, Inserm UMR 1087-CNRS UMR 6291, institut du thorax, CHU de Nantes, Nantes, France.

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March 2016

[Cardiovascular risk: what is the role of HDL cholesterol?]

Authors:
Bertrand Cariou

Rev Prat 2016 03;66(3):330-331

Clinique d'endocrinologie, Inserm UMR 1087-CNRS UMR 6291, institut du thorax, CHU de Nantes, Nantes, France.

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March 2016

Vitamin D deficiency is an independent risk factor for PTDM after kidney transplantation.

Transpl Int 2016 Feb 29;29(2):207-15. Epub 2015 Oct 29.

Institute of Transplantation, Urology and Nephrology (ITUN), Nantes University Hospital, Nantes, France.

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http://doi.wiley.com/10.1111/tri.12697
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http://dx.doi.org/10.1111/tri.12697DOI Listing
February 2016

Urine-sample-derived human induced pluripotent stem cells as a model to study PCSK9-mediated autosomal dominant hypercholesterolemia.

Dis Model Mech 2016 Jan 19;9(1):81-90. Epub 2015 Nov 19.

INSERM, UMR1087, L'institut du thorax, Nantes F-44000, France CNRS, UMR 6291, Nantes F-44000, France Université de Nantes, Nantes F-44000, France CHU Nantes, L'institut du thorax, CIC Endocrinology-Nutrition, Nantes F-44000, France.

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http://dmm.biologists.org/content/dmm/early/2015/11/19/dmm.0
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http://dmm.biologists.org/lookup/doi/10.1242/dmm.022277
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http://dx.doi.org/10.1242/dmm.022277DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728336PMC
January 2016

mTOR inhibitors and diabetes.

Diabetes Res Clin Pract 2015 Nov 21;110(2):101-8. Epub 2015 Sep 21.

INSERM CRI 866, Medicine University, Dijon, France; Clinique d'Endocrinologie, l'institut du thorax, CHU de Nantes, Nantes, France; INSERM, UMR1087, l'institut du thorax, Nantes, France; Faculté de Médecine, Université de Nantes, Nantes, France.

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https://linkinghub.elsevier.com/retrieve/pii/S01688227150039
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http://dx.doi.org/10.1016/j.diabres.2015.09.014DOI Listing
November 2015

PCSK9 Inhibition: Does Lipoprotein Size Matter?

J Am Heart Assoc 2015 Nov 19;4(11). Epub 2015 Nov 19.

INSERM, UMR1087, l'institut du thorax, Nantes, France (K.S.T., B.C.) CNRS, UMR 6291, Nantes, France (K.S.T., B.C.) Université de Nantes, Nantes, France (K.S.T., B.C.) CHU Nantes, l'institut du thorax, CIC Endocrinology-Nutrition, Nantes, France (B.C.).

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http://dx.doi.org/10.1161/JAHA.115.002806DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4845216PMC
November 2015

Long-term effects of Roux-en-Y gastric bypass on postprandial plasma lipid and bile acids kinetics in female non diabetic subjects: A cross-sectional pilot study.

Clin Nutr 2015 Oct 26;34(5):911-7. Epub 2014 Sep 26.

Center for Metabolic Diseases, Department of Internal Medicine, Broye Intercantonal Hospital, Estavayer-le-lac, Switzerland.

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http://dx.doi.org/10.1016/j.clnu.2014.09.018DOI Listing
October 2015

[A YOUNG MAN WHOSE LDL-CHOLESTEROL IS GREATER THAN 1.9 G/L].

Authors:
Bertrand Cariou

Rev Prat 2015 Oct;65(8):1062-6

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October 2015

The loss-of-function PCSK9 p.R46L genetic variant does not alter glucose homeostasis.

Diabetologia 2015 Sep 7;58(9):2051-5. Epub 2015 Jun 7.

European Genomic Institute for Diabetes (EGID), FR 3508, Lille, France.

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http://dx.doi.org/10.1007/s00125-015-3659-8DOI Listing
September 2015

Patient and Physician Perspectives on Mode of Administration of the PCSK9 Monoclonal Antibody Alirocumab, an Injectable Medication to Lower LDL-C Levels.

Clin Ther 2015 Sep 14;37(9):1945-1954.e6. Epub 2015 Aug 14.

Department of Endocrinology, l'Institut du Thorax, Nantes University Hospital, Nantes, France.

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http://dx.doi.org/10.1016/j.clinthera.2015.07.008DOI Listing
September 2015

[Hormonal evaluation of adrenal incidentalomas].

Ann Biol Clin (Paris) 2014 Nov-Dec;72(6):629-37

Laboratoire de biochimie, CHU de Nantes-Hotel Dieu, Nantes, France.

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http://dx.doi.org/10.1684/abc.2014.1013DOI Listing
August 2015

Clinical use of insulin degludec.

Diabetes Res Clin Pract 2015 Jul 14;109(1):19-31. Epub 2015 Apr 14.

Division of Endocrinology, Department of Internal Medicine, University of Texas Southwestern Medical Center and Parkland Health & Hospital System, Dallas, TX, USA.

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http://dx.doi.org/10.1016/j.diabres.2015.04.002DOI Listing
July 2015

Role of PCSK9 beyond liver involvement.

Curr Opin Lipidol 2015 Jun;26(3):155-61

aInserm, UMR1087-CNRS UMR6291, l'Institut du Thorax bUniversité de Nantes, Faculté de Médecine, Institut du Thorax cDepartment of Endocrinology, l'Institut du Thorax, University Hospital of Nantes, Nantes, France.

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http://dx.doi.org/10.1097/MOL.0000000000000180DOI Listing
June 2015

Letter from Le May and Cariou regarding article, "Proprotein convertase subtilisin kexin type 9 promotes intestinal overproduction of triglyceride-rich apolipoprotein B lipoproteins through both low-density lipoprotein receptor-dependent and -independent mechanisms".

Circulation 2015 May;131(18):e427

INSERM, UMR1087-CNRS UMR6291, l'Institut du Thorax, Nantes, France, Université de Nantes, Faculté de Médecine, Institut du Thorax, Nantes, France, Department of Endocrinology, University Hospital of Nantes, Nantes, France.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.114.011697DOI Listing
May 2015

Management of thyroid nodules incidentally discovered on MIBI scanning for primary hyperparathyroidism.

Langenbecks Arch Surg 2015 Apr 20;400(3):313-8. Epub 2015 Feb 20.

Clinique de Chirurgie Digestive et Endocrinienne (CCDE), Institut des Maladies de l'Appareil Digestif (IMAD), Centre Hospitalier Universitaire (CHU) Nantes-Hôtel Dieu, Place Alexis Ricordeau, 44093, Nantes, France.

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http://dx.doi.org/10.1007/s00423-015-1286-yDOI Listing
April 2015

PCSK9-deficiency does not alter blood pressure and sodium balance in mouse models of hypertension.

Atherosclerosis 2015 Mar 19;239(1):252-9. Epub 2015 Jan 19.

INSERM, UMR1087-CNRS UMR6291, l'Institut du Thorax, F-44000 Nantes, France; Université de Nantes, Institut du Thorax, F-44000 Nantes, France; Department of Endocrinology, University Hospital of Nantes, F-44000 Nantes, France. Electronic address:

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http://dx.doi.org/10.1016/j.atherosclerosis.2015.01.012DOI Listing
March 2015

The dual peroxisome proliferator-activated receptor alpha/delta agonist GFT505 exerts anti-diabetic effects in db/db mice without peroxisome proliferator-activated receptor gamma-associated adverse cardiac effects.

Diab Vasc Dis Res 2014 Nov 11;11(6):440-7. Epub 2014 Sep 11.

Institut Pasteur de Lille, Lille, France Inserm, UMR 1011, Lille, France Université de Lille 2, Lille, France EGID, Lille, France

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http://dx.doi.org/10.1177/1479164114548027DOI Listing
November 2014

GFT505 for the treatment of nonalcoholic steatohepatitis and type 2 diabetes.

Expert Opin Investig Drugs 2014 Oct 28;23(10):1441-8. Epub 2014 Aug 28.

Clinique d'Endocrinologie, CHU de Nantes , Nantes, F-44000 , France.

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http://dx.doi.org/10.1517/13543784.2014.954034DOI Listing
October 2014

[Trans-intestinal cholesterol excretion (TICE): a new route for cholesterol excretion].

Med Sci (Paris) 2014 Oct 14;30(10):896-901. Epub 2014 Oct 14.

IRS-UN, institut du thorax, unité Inserm UMR 1087/CNRS UMR 6291, 8, quai Moncousu, 44007 Nantes Cedex 1, France.

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http://dx.doi.org/10.1051/medsci/20143010017DOI Listing
October 2014

Congenital lipodystrophies and dyslipidemias.

Curr Atheroscler Rep 2014 Sep;16(9):437

INSERM U1087-CNRS UMR 6291, L'institut du Thorax, 8 quai Moncousu, 44007, Nantes Cedex 1, France,

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http://dx.doi.org/10.1007/s11883-014-0437-xDOI Listing
September 2014

Preserved adrenal function in fully PCSK9-deficient subject.

Int J Cardiol 2014 Sep 12;176(2):499-500. Epub 2014 Jul 12.

INSERM, UMR1087, CNRS UMR6291, l'Institut du Thorax, F-44000 Nantes, France.

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https://linkinghub.elsevier.com/retrieve/pii/S01675273140124
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http://dx.doi.org/10.1016/j.ijcard.2014.07.057DOI Listing
September 2014

Mosaicism in HIF2A-related polycythemia-paraganglioma syndrome.

J Clin Endocrinol Metab 2014 Feb 25;99(2):E369-73. Epub 2013 Nov 25.

Assistance Publique-Hôpitaux de Paris (A.B., C.S., A-P.G.-R.), Hôpital Européen Georges Pompidou (HEGP), Service de Génétique, 75908 Paris, France; Clinique d'Endocrinologie (S.S., M.L., A.M., B.C.), l'Institut du Thorax, Centre Hospitalier Universitaire (CHU) de Nantes, 44007 Nantes, France; Département d'Oncologie et d'Hématologie Pédiatriques et de Thérapie Cellulaire (L.M.), CHU de Nancy, Hôpital d'Enfants, 54500 Vandœuvre-lès-Nancy, France; Inserm (M.M., J.F., A.-P.G.-R.), Unité Mixte de Recherche 970, Centre de recherche cardiovasculaire de l'HEGP, 75015 Paris, France; Service d'Anatomopathologie (M.-F.H.), CHU de Nantes, 44007 Nantes, France; INSERM (M.-F.H.), UMR957, Faculté de Médecine, 44035 Nantes, France; and Université Paris Descartes (J.F., A.-P.G.-R.), Faculté de Médecine, 75006 Paris Cité Sorbonne, France.

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http://dx.doi.org/10.1210/jc.2013-2600DOI Listing
February 2014

[Management of metabolic disorders induced by everolimus in patients with differentiated neuroendocrine tumors: expert proposals].

Bull Cancer 2014 Feb;101(2):175-83

Hôpital Beaujon, service de gastroentérologie-pancréatologie (PMAD), 100, boulevard du Général-Leclerc, 92118 Clichy, France.

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http://dx.doi.org/10.1684/bdc.2014.1887DOI Listing
February 2014