Publications by authors named "Bertram Bengsch"

57Publications

IL-2 contributes to cirrhosis-associated immune dysfunction by impairing follicular T helper cells in advanced cirrhosis.

J Hepatol 2020 Oct 24. Epub 2020 Oct 24.

Department of Medicine II, Medical Center - University of Freiburg, Germany; Faculty of Medicine, University of Freiburg, Germany; Berta-Ottenstein-Programme, Faculty of Medicine, University of Freiburg, Germany. Electronic address:

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October 2020

Shed it, and help-LAG3 cleavage drives conventional CD4 T cells to overcome resistance to PD-1 immunotherapy.

Sci Immunol 2020 07;5(49)

Faculty of Medicine, Department of Medicine II, Gastroenterology, Hepatology, Endocrinology, and Infectious Disease, University Medical Center Freiburg, Freiburg, Germany.

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July 2020

Exhausted phenotype of follicular CD8 T cells in CVID.

J Allergy Clin Immunol 2020 Oct 10;146(4):912-915.e13. Epub 2020 Mar 10.

Divison of Immunodeficiency, Department of Rheumatology and Clinical Immunology, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany; Center for Chronic Immunodeficiency (CCI), Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany. Electronic address:

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October 2020

Use of Mass Cytometry to Profile Human T Cell Exhaustion.

Front Immunol 2019 22;10:3039. Epub 2020 Jan 22.

Department of Medicine II, Gastroenterology, Hepatology, Endocrinology, and Infectious Diseases, Faculty of Medicine, University Medical Center Freiburg, Freiburg, Germany.

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November 2020

Exploration of T-Cell Diversity Using Mass Cytometry.

Methods Mol Biol 2020 ;2111:1-20

Department of Systems Pharmacology and Translational Therapeutics, Institute for Immunology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, USA.

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January 2020

TCF-1-Centered Transcriptional Network Drives an Effector versus Exhausted CD8 T Cell-Fate Decision.

Immunity 2019 11 9;51(5):840-855.e5. Epub 2019 Oct 9.

Department of Systems Pharmacology and Translational Therapeutics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Institute for Immunology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA; Parker Institute for Cancer Immunotherapy at University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address:

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November 2019

Common variable immunodeficiency-associated endotoxemia promotes early commitment to the T follicular lineage.

J Allergy Clin Immunol 2019 12 22;144(6):1660-1673. Epub 2019 Aug 22.

Division of Immunology and Allergy, Children's Hospital of Philadelphia, Philadelphia, Pa; Department of Pediatrics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pa; Institute for Immunology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pa. Electronic address:

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December 2019

Success of immune checkpoint blockade therapies - mechanisms and implications for hepatology.

Z Gastroenterol 2019 Jan 14;57(1):74-86. Epub 2019 Jan 14.

Department of Medicine II, Gastroenterology, Hepatology, Endocrinology, and Infectious Diseases, University Medical Center Freiburg, Faculty of Medicine, Germany.

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January 2019

Epigenomic-Guided Mass Cytometry Profiling Reveals Disease-Specific Features of Exhausted CD8 T Cells.

Immunity 2018 05;48(5):1029-1045.e5

Department of Microbiology, University of Pennsylvania Perelman School Medicine, Philadelphia, PA, USA; Institute for Immunology, University of Pennsylvania Perelman School Medicine, Philadelphia, PA, USA; Parker Institute for Cancer Immunotherapy, University of Pennsylvania Perelman School Medicine, Philadelphia, PA, USA. Electronic address:

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May 2018

Outcome of Antiviral Immunity in the Liver Is Shaped by the Level of Antigen Expressed in Infected Hepatocytes.

Hepatology 2018 12 27;68(6):2089-2105. Epub 2018 Sep 27.

Institute of Molecular Immunology and Experimental Oncology, Klinikum Rechts der Isar, Technical University of Munich, Germany.

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December 2018

For whom the interferons toll - TLR7 mediated boosting of innate and adaptive immunity against chronic HBV infection.

J Hepatol 2018 05 3;68(5):883-886. Epub 2018 Mar 3.

Department of Medicine II, Gastroenterology, Hepatology, Endocrinology, and Infectious Diseases, University Medical Center Freiburg, Germany. Electronic address:

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May 2018

Differentiation and Protective Capacity of Virus-Specific CD8 T Cells Suggest Murine Norovirus Persistence in an Immune-Privileged Enteric Niche.

Immunity 2017 10 11;47(4):723-738.e5. Epub 2017 Oct 11.

Department of Microbiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA; Institute for Immunology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA. Electronic address:

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October 2017

Protein-losing pseudomembranous colitis with cap polyposis-like features.

World J Gastroenterol 2017 Apr;23(16):3003-3010

Wolfgang Kreisel, Bertram Bengsch, Anna-Maria Globig, Department of Medicine II, Gastroenterology, Hepatology, Endocrinology and Infectious Diseases, Medical Center, University of Freiburg, Faculty of Medicine, University of Freiburg, 79106 Freiburg, Germany.

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April 2017

Deep immune profiling by mass cytometry links human T and NK cell differentiation and cytotoxic molecule expression patterns.

J Immunol Methods 2018 02 19;453:3-10. Epub 2017 Mar 19.

Department of Microbiology, University of Pennsylvania Perelman School Medicine, Philadelphia, PA 19104, USA; Institute for Immunology, University of Pennsylvania Perelman School Medicine, Philadelphia, PA 19104, USA. Electronic address:

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February 2018

Evolution in Our Understanding of Hepatitis B Virus Virology and Immunology.

Clin Liver Dis 2016 11 12;20(4):629-644. Epub 2016 Aug 12.

Medical Research, Philadelphia Corporal Michael J. Crescenz VA Medical Center (CMC VAMC), A424, University and Woodland Avenue, Philadelphia, PA 19104, USA; Division of Gastroenterology, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, 421 Curie Boulevard, Philadelphia, PA 19104, USA. Electronic address:

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November 2016

Bioenergetic Insufficiencies Due to Metabolic Alterations Regulated by the Inhibitory Receptor PD-1 Are an Early Driver of CD8(+) T Cell Exhaustion.

Immunity 2016 08 2;45(2):358-73. Epub 2016 Aug 2.

Department of Microbiology, University of Pennsylvania Perelman School Medicine, Philadelphia, PA 19104, USA; Institute for Immunology, University of Pennsylvania Perelman School Medicine, Philadelphia, PA 19104, USA. Electronic address:

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August 2016

Cutting Edge: IL-4, IL-21, and IFN-γ Interact To Govern T-bet and CD11c Expression in TLR-Activated B Cells.

J Immunol 2016 08 18;197(4):1023-8. Epub 2016 Jul 18.

Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104; Institute for Immunology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104;

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August 2016

The importance of cooperation: partnerless NFAT induces T cell exhaustion.

Immunity 2015 Feb;42(2):203-205

Institute for Immunology, Department of Microbiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA. Electronic address:

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February 2015

Comprehensive intestinal T helper cell profiling reveals specific accumulation of IFN-γ+IL-17+coproducing CD4+ T cells in active inflammatory bowel disease.

Inflamm Bowel Dis 2014 Dec;20(12):2321-9

*Department of Medicine II, †Institute for Clinical Pathology, and ‡Department of Surgery, University Hospital of Freiburg, Freiburg, Germany.

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December 2014

Restoration of HBV-specific CD8+ T cell function by PD-1 blockade in inactive carrier patients is linked to T cell differentiation.

J Hepatol 2014 Dec 10;61(6):1212-9. Epub 2014 Jul 10.

Department of Medicine II, University Hospital of Freiburg, Germany. Electronic address:

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December 2014

Balance lost: T cell immunity in progressive HBV infection.

Hepatol Int 2014 Jan 9;8(1):7-9. Epub 2014 Jan 9.

Department of Medicine II, University Hospital of Freiburg, Freiburg, Germany.

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January 2014

[Serologic pitfalls in the diagnosis of hepatopathy of uncertain origin].

Praxis (Bern 1994) 2013 Jan;102(3):169-73

Abteilung Innere Medizin II, Uniklinik Freiburg, Deutschland.

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January 2013

Factors that determine the antiviral efficacy of HCV-specific CD8(+) T cells ex vivo.

Gastroenterology 2013 Feb 7;144(2):426-36. Epub 2012 Nov 7.

Department of Medicine II, University Hospital of Freiburg, Freiburg, Germany.

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February 2013

Human Th17 cells express high levels of enzymatically active dipeptidylpeptidase IV (CD26).

J Immunol 2012 Jun 25;188(11):5438-47. Epub 2012 Apr 25.

Department of Medicine II, University Hospital of Freiburg, 79106 Freiburg, Germany.

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June 2012

Role of host genetic factors in the outcome of hepatitis C virus infection.

Viruses 2009 Sep 5;1(2):104-25. Epub 2009 Aug 5.

Department of Medicine II, University Hospital Freiburg, 79106 Freiburg, Germany; E-Mails: (B.B.), (H.B.).

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September 2009

Memory CD8+ T cell differentiation in viral infection: a cell for all seasons.

World J Gastroenterol 2007 Sep;13(36):4848-57

Emory University School of Medicine, 954 Gatewood Road, NE, Atlanta, GA 30329, United States.

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September 2007