Publications by authors named "Bert A van der Reijden"

66Publications

Transcription factor 4 (TCF4) expression predicts clinical outcome in RUNX1 mutated and translocated acute myeloid leukemia.

Haematologica 2020 Jun 5;105(9):e454-457. Epub 2020 Jun 5.

Department of Laboratory Medicine, Laboratory of Hematology, Radboud University Medical Centrer, Nijmegen, the Netherlands.

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http://dx.doi.org/10.3324/haematol.2019.232827DOI Listing
June 2020

A collapse for venous thromboembolism.

Blood 2020 Jul;136(5):523-524

Radboud University Medical Center.

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http://dx.doi.org/10.1182/blood.2020006457DOI Listing
July 2020

Mutational spectrum and dynamics of clonal hematopoiesis in anemia of older individuals.

Blood 2020 Apr;135(14):1161-1170

Department of Hematology, University Medical Center Groningen, University of Groningen, Groningen, The Netherlands.

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http://dx.doi.org/10.1182/blood.2019004362DOI Listing
April 2020

Platelet CD34 expression in a patient with a partial deletion of transcription factor subunit CBFB.

Am J Hematol 2020 06 8;95(6):E136-E139. Epub 2020 Apr 8.

Department of Laboratory Medicine, Laboratory of Hematology, Radboudumc and Radboud Institute for Molecular Life Sciences, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1002/ajh.25770DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7317484PMC
June 2020

Targeting the GFI1/1B-CoREST Complex in Acute Myeloid Leukemia.

Front Oncol 2019 9;9:1027. Epub 2019 Oct 9.

Laboratory of Hematology, Department of Laboratory Medicine, Radboud Institute for Molecular Life Sciences, Radboud University Medical Center, Nijmegen, Netherlands.

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http://dx.doi.org/10.3389/fonc.2019.01027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6794713PMC
October 2019

Whole exome sequencing in the diagnostic workup of patients with a bleeding diathesis.

Haemophilia 2019 Jan 15;25(1):127-135. Epub 2018 Nov 15.

Department of Hematology, Radboud University Medical Center, Nijmegen, The Netherlands.

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http://doi.wiley.com/10.1111/hae.13638
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http://dx.doi.org/10.1111/hae.13638DOI Listing
January 2019

Evaluating Variant Calling Tools for Non-Matched Next-Generation Sequencing Data.

Sci Rep 2017 02 24;7:43169. Epub 2017 Feb 24.

Institute of Medical Informatics, University of Münster, Münster, 48149, Germany.

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http://dx.doi.org/10.1038/srep43169DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5324109PMC
February 2017

Apoptosis-Related Gene Expression Profiling in Hematopoietic Cell Fractions of MDS Patients.

PLoS One 2016 30;11(11):e0165582. Epub 2016 Nov 30.

Department of Laboratory Medicine, Laboratory of Hematology, Radboud University Medical Center (Radboudumc), Nijmegen, The Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0165582PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5130187PMC
September 2017

5-Hydroxymethylcytosine: An epigenetic mark frequently deregulated in cancer.

Biochim Biophys Acta 2015 Apr 8;1855(2):144-54. Epub 2015 Jan 8.

Department of Laboratory Medicine, Laboratory of Hematology, Radboud University Medical Center and Radboud Institute for Molecular Life Sciences, PO Box 9101, 6500 HB Nijmegen, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.bbcan.2015.01.001DOI Listing
April 2015

High expression of transcription factor 4 (TCF4) is an independent adverse prognostic factor in acute myeloid leukemia that could guide treatment decisions.

Haematologica 2014 Dec 22;99(12):e257-9. Epub 2014 Aug 22.

Department of Laboratory medicine, Laboratory of Hematology, RadboudUMC; and Department of Hematology, RadboudUMC, Nijmegen, The Netherlands

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http://dx.doi.org/10.3324/haematol.2014.110437DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4258745PMC
December 2014

Characterization of acute myeloid leukemia based on levels of global hydroxymethylation.

Blood 2014 Aug 1;124(7):1110-8. Epub 2014 Jul 1.

Department of Laboratory Medicine, Laboratory of Hematology, Radboud University Medical Center and Radboud Institute for Molecular Life Sciences, Nijmegen, The Netherlands;

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http://dx.doi.org/10.1182/blood-2013-08-518514DOI Listing
August 2014

A dominant-negative GFI1B mutation in the gray platelet syndrome.

N Engl J Med 2014 Jan 10;370(3):245-53. Epub 2013 Dec 10.

From the Department of Laboratory Medicine, Laboratory of Hematology, Radboud University Medical Center, Nijmegen Center for Molecular Life Sciences (D.M., A.E.M., S.M.B., H.V., G.H., F.P., W.V.H., J.H.J., B.A.V.R.) and the Departments of Pathology (K.M.H., B.W.), Hematology (B.A.P.L.G., M.A.M., G.H.), Cardiology (A.L.D.), and Human Genetics (S.S., M.J.E.K.), Radboud University Medical Center - all in Nijmegen, the Netherlands; the Department of Medical Genetics, Antwerp University Hospital and University of Antwerp (N.A.B., E.F., G.V.C., B.L.L., L.V.L.) and the Statua Center for Statistics, University of Antwerp (E.F.), Antwerp, Belgium; and the Department of Hematology, University Hospital, Essen, Germany (C.K., L.B.).

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http://dx.doi.org/10.1056/NEJMoa1308130DOI Listing
January 2014

Identification of the ubiquitin ligase Triad1 as a regulator of endosomal transport.

Biol Open 2012 Jun 9;1(6):607-14. Epub 2012 May 9.

Department of Cell Biology and Institute of Biomembranes, University Medical Center Utrecht , 3584 CX Utrecht , The Netherlands.

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http://dx.doi.org/10.1242/bio.2012778DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3509441PMC
June 2012

High GATA2 expression is a poor prognostic marker in pediatric acute myeloid leukemia.

Blood 2012 Sep 11;120(10):2064-75. Epub 2012 Jul 11.

Department of Laboratory Medicine, Laboratory of Hematology, Radboud University Nijmegen Medical Centre and Nijmegen Centre for Molecular Life Sciences, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1182/blood-2011-12-397083DOI Listing
September 2012

Expression of the BRCA1 complex member BRE predicts disease free survival in breast cancer.

Breast Cancer Res Treat 2012 Aug 16;135(1):125-33. Epub 2012 Jun 16.

Department of Laboratory Medicine, Laboratory of Hematology, Radboud University Nijmegen Medical Centre, Nijmegen Centre for Molecular Life Sciences, Geert Grooteplein Zuid 8, 6525 GA Nijmegen, The Netherlands.

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http://dx.doi.org/10.1007/s10549-012-2122-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3413819PMC
August 2012

Mutations in epigenetic regulators in myelodysplastic syndromes.

Int J Hematol 2012 Jan 11;95(1):8-16. Epub 2012 Jan 11.

Laboratory of Hematology, Department of Laboratory Medicine, Radboud University Nijmegen Medical Centre and Nijmegen Centre for Molecular Life Sciences, Geert Grooteplein zuid 8, 6525 GA Nijmegen, The Netherlands.

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http://link.springer.com/10.1007/s12185-011-0996-3
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http://dx.doi.org/10.1007/s12185-011-0996-3DOI Listing
January 2012

High BRE expression predicts favorable outcome in adult acute myeloid leukemia, in particular among MLL-AF9-positive patients.

Blood 2011 Nov 21;118(20):5613-21. Epub 2011 Sep 21.

Department of Laboratory Medicine, Laboratory of Hematology, Radboud University Nijmegen Medical Centre, Nijmegen Centre for Molecular Life Sciences, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1182/blood-2011-06-359182DOI Listing
November 2011

Hematopoietic stem cells exhibit a specific ABC transporter gene expression profile clearly distinct from other stem cells.

BMC Pharmacol 2010 Sep 13;10:12. Epub 2010 Sep 13.

Department of Laboratory Medicine, Laboratory of Hematology, Radboud University Nijmegen Medical Centre/Nijmegen Centre for Molecular Life Sciences, Geert Grooteplein 8, 6525GA Nijmegen, The Netherlands.

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http://bmcpharma.biomedcentral.com/articles/10.1186/1471-221
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http://dx.doi.org/10.1186/1471-2210-10-12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2945345PMC
September 2010

Somatic mutations of the histone methyltransferase gene EZH2 in myelodysplastic syndromes.

Nat Genet 2010 Aug 4;42(8):665-7. Epub 2010 Jul 4.

Department of Laboratory Medicine, Radboud University, Nijmegen Medical Centre, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1038/ng.620DOI Listing
August 2010

Chemokine induction by all-trans retinoic acid and arsenic trioxide in acute promyelocytic leukemia: triggering the differentiation syndrome.

Blood 2009 Dec 14;114(27):5512-21. Epub 2009 Oct 14.

Central Hematology Laboratory and Department of Hematology, Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen Medical Centre, Nijmegen.

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http://dx.doi.org/10.1182/blood-2009-02-204834DOI Listing
December 2009

MicroRNA hsa-miR-135b regulates mineralization in osteogenic differentiation of human unrestricted somatic stem cells.

Stem Cells Dev 2010 Jun;19(6):877-85

Central Hematology Laboratory, Radboud University Nijmegen Medical Centre, Nijmegen Center for Molecular Life Sciences, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1089/scd.2009.0112DOI Listing
June 2010

Acquired mutations in TET2 are common in myelodysplastic syndromes.

Nat Genet 2009 Jul 31;41(7):838-42. Epub 2009 May 31.

Department of Hematology and Central Hematology Laboratory, Radboud University Nijmegen Medical Centre and Nijmegen Centre for Molecular Life Sciences, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1038/ng.391DOI Listing
July 2009

Growth factor independent 1b (Gfi1b) and a new splice variant of Gfi1b are highly expressed in patients with acute and chronic leukemia.

Int J Hematol 2009 May 10;89(4):422-430. Epub 2009 Apr 10.

Institut für Zellbiologie (Tumorforschung), IFZ, Universitätsklinikum Essen, Virchowstrasse 173, 45122, Essen, Germany.

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http://dx.doi.org/10.1007/s12185-009-0286-5DOI Listing
May 2009

Gene transactivation without direct DNA binding defines a novel gain-of-function for PML-RARalpha.

Blood 2008 Feb 19;111(3):1634-43. Epub 2007 Nov 19.

Central Hematology Laboratory and Department of Hematology, Nijmegen Centre for Molecular Life Sciences, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1182/blood-2007-04-081125DOI Listing
February 2008

Gfi1 ubiquitination and proteasomal degradation is inhibited by the ubiquitin ligase Triad1.

Blood 2007 Nov 23;110(9):3128-35. Epub 2007 Jul 23.

Central Hematology Laboratory, Radboud University Nijmegen Medical Centre, Nijmegen Centre for Molecular Life Sciences, 6500 HB Nijmegen, the Netherlands.

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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2006-11-05
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http://dx.doi.org/10.1182/blood-2006-11-058602DOI Listing
November 2007

Diminished proteasomal degradation results in accumulation of Gfi1 protein in monocytes.

Blood 2007 Jan 3;109(1):100-8. Epub 2006 Aug 3.

Central Hematology Laboratory, Radboud University Nijmegen Medical Centre for Molecular Life Sciences (NCMLS), PO Box 9101, 6500 HB Nijmegen, The Netherlands.

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http://dx.doi.org/10.1182/blood-2006-02-003590DOI Listing
January 2007

ABCB1 modulation does not circumvent drug extrusion from primitive leukemic progenitor cells and may preferentially target residual normal cells in acute myelogenous leukemia.

Clin Cancer Res 2006 Jun;12(11 Pt 1):3452-8

Department of Hematology and Central Hematology Laboratory, University Medical Center Nijmegen, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1158/1078-0432.CCR-05-1945DOI Listing
June 2006

Diagnosis and monitoring of CBFB-MYH11-positive acute myeloid leukemia by qualitative and quantitative RT-PCR.

Methods Mol Med 2006 ;125:163-75

Central Hematology Laboratory, University Medical Center St Raboud, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1385/1-59745-017-0:163DOI Listing
April 2006

Isolation of RNA and DNA from leukocytes and cDNA synthesis.

Methods Mol Med 2006 ;125:1-11

Central Hematology Laboratory, University Medical Center St Raboud, The Netherlands.

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http://dx.doi.org/10.1385/1-59745-017-0:1DOI Listing
April 2006

Isolation of FRET-positive cells using single 408-nm laser flow cytometry.

Cytometry A 2006 Apr;69(4):291-8

Central Hematology Laboratory of the University Medical Centre, St. Radboud, Geert Grooteplein zuid 8, 6500 HB Nijmegen, The Netherlands.

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http://dx.doi.org/10.1002/cyto.a.20254DOI Listing
April 2006

The E3 ubiquitin-protein ligase Triad1 inhibits clonogenic growth of primary myeloid progenitor cells.

Blood 2005 Dec 23;106(13):4114-23. Epub 2005 Aug 23.

Central Hematology Laboratory, University Medical Center Nijmegen, PO BOX 9101, 6500 HB Nijmegen, The Netherlands.

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http://dx.doi.org/10.1182/blood-2005-04-1450DOI Listing
December 2005

Breast cancer resistance protein in drug resistance of primitive CD34+38- cells in acute myeloid leukemia.

Clin Cancer Res 2005 Mar;11(6):2436-44

Department of Hematology and Central Hematology Laboratory, University Medical Center Nijmegen, St. Radboud, 6500 HB Nijmegen, the Netherlands.

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http://dx.doi.org/10.1158/1078-0432.CCR-04-0212DOI Listing
March 2005

Bcl-2 prevents loss of mitochondria in CCCP-induced apoptosis.

Exp Cell Res 2004 Oct;299(2):533-40

Central Hematology Laboratory, Department of Hematology, University Medical Center Nijmegen, Nijmegen 6500 HB, The Netherlands.

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http://dx.doi.org/10.1016/j.yexcr.2004.06.024DOI Listing
October 2004

Epigenetic regulation of tumor suppressors in t(8:21)-containing AML.

Ann Hematol 2004 Jun 30;83(6):329-30. Epub 2004 Mar 30.

Department of Biochemistry, Vanderbilt University School of Medicine, PRB 512, 23rd and Pierce, Nashville, Tennessee 37232, USA.

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http://dx.doi.org/10.1007/s00277-003-0841-8DOI Listing
June 2004