Bernhard Landwehrmeyer

Bernhard Landwehrmeyer

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Bernhard Landwehrmeyer

Bernhard Landwehrmeyer

Publications by authors named "Bernhard Landwehrmeyer"

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PET molecular imaging of phosphodiesterase 10A: An early biomarker of Huntington's disease progression.

Mov Disord 2020 Jan 22. Epub 2020 Jan 22.

Centre for Psychiatry Research, Department of Clinical Neuroscience, Karolinska Institutet, & Stockholm Health Care Services, Region Stockholm, Sweden.

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http://dx.doi.org/10.1002/mds.27963DOI Listing
January 2020

Movement Disorder Society Task Force Viewpoint: Huntington's Disease Diagnostic Categories.

Mov Disord Clin Pract 2019 Sep 23;6(7):541-546. Epub 2019 Aug 23.

Huntington's Disease Centre, University College London Queen Square Institute of Neurology London United Kingdom.

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http://dx.doi.org/10.1002/mdc3.12808DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6749806PMC
September 2019

An International Validation of a Clinical Tool to Assess Carers' Quality of Life in Huntington's Disease.

Front Psychol 2019 23;10:1658. Epub 2019 Jul 23.

School of Psychology and Clinical Language Sciences, University of Reading, Reading, United Kingdom.

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http://dx.doi.org/10.3389/fpsyg.2019.01658DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6676956PMC
July 2019

Targeting Huntingtin Expression in Patients with Huntington's Disease.

N Engl J Med 2019 06 6;380(24):2307-2316. Epub 2019 May 6.

From University College London (UCL) Huntington's Disease Centre, Department of Neurodegenerative Disease, Queen Square Institute of Neurology, UCL, and the U.K. Dementia Research Institute at UCL, London (S.J.T., E.J.W.), the Department of Clinical Neuroscience, Addenbrooke's Hospital, University of Cambridge, Cambridge (R.A.B., N.F.B.), Manchester Centre for Genomic Medicine, St. Mary's Hospital, Manchester University NHS Foundation Trust, and the Division of Evolution and Genomic Sciences, School of Biological Sciences, Faculty of Biology, Medicine, and Health, University of Manchester, Manchester Academic Health Science Centre, Manchester (D.C.), the University of Edinburgh and the U.K. Dementia Research Institute, Edinburgh (J.P.), the Institute of Clinical Sciences, College of Medical and Dental Sciences, University Hospital Birmingham, Birmingham (H.R.), and the Cardiff University Brain Repair Group, Brain Repair and Intracranial Neurotherapeutics Unit, Neuroscience and Mental Health Research Institute and School of Biosciences, Cardiff (A.R.) - all in the United Kingdom; the Centre for Huntington's Disease, Department of Medical Genetics, and the Division of Neurology, Department of Medicine, University of British Columbia, and the Centre for Molecular Medicine and Therapeutics, B.C. Children's Hospital, Vancouver, Canada (B.R.L.); the Department of Neurology, Ulm University, Huntington's Disease Centre, Ulm (G.B.L.), the Department of Neurology, Huntington Center North Rhine-Westphalia, Ruhr University Bochum, St. Josef-Hospital, Bochum (C.S.), and the Department of Neuropsychiatry, Charité-Universitätsmedizin Berlin, Deutsches Zentrum für Neurodegenerative Erkrankungen, Berlin (J.P.) - all in Germany; Ionis Pharmaceuticals, Carlsbad, CA (H.B.K., E.E.S., D.A.N., T.B., E.P., A.V.S., C.F.B., R.M.L.); and F. Hoffmann-La Roche, Basel, Switzerland (C.C., I.G., S.A.S.).

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http://dx.doi.org/10.1056/NEJMoa1900907DOI Listing
June 2019

Defining pediatric huntington disease: Time to abandon the term Juvenile Huntington Disease?

Mov Disord 2019 04 20;34(4):584-585. Epub 2019 Feb 20.

Swiss HD Center, Neurozentrum Siloah and Department of Neurology, University of Bern, Bern, Switzerland.

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http://dx.doi.org/10.1002/mds.27640DOI Listing
April 2019

Serum neurofilament light chain in behavioral variant frontotemporal dementia.

Neurology 2018 10 12;91(15):e1390-e1401. Epub 2018 Sep 12.

From the Department of Neurology (P.S., S.A.-S., E.S., I.U., C.A.F.v.A., J. Kassubek, B.L., P.O., A.C.L., M.O.) and Institute of Epidemiology and Medical Biometry (B.M.), University of Ulm; Department of Psychiatry and Psychotherapy (J.D.-S., H.F., T.G.), Klinikum Rechts der Isar, Technical University of Munich; Department of Nuclear Medicine (H.B.), Leipzig University Hospital; Department of Neurology (A.D.), Ludwig-Maximilians-University, Munich; Department of Neurology (K.F.), Saarland University, Homburg; Department of Psychiatry and Psychotherapy (K.F.), University of Bonn, Germany; Swiss Epilepsy Center (H.-J.H.), Zurich, Switzerland; Department of Psychiatry and Psychotherapy (H.J.), University Medical Center Hamburg-Eppendorf, Hamburg; AMEOS Klinikum (H.J.), Heiligenhafen; Department of Psychiatry and Psychotherapy (J. Kornhuber, J.M.M.), Friedrich-Alexander-University of Erlangen-Nuremberg, Erlangen; Department of Psychiatry and Psychotherapy (M.L.), University of Würzburg; Department of Neurology (J.P.), University of Rostock; DZNE (J.P.), Rostock; Department of Neurodegenerative Diseases and Geriatric Psychiatry (A.S.), University Hospital Bonn; DZNE (A.S.), Bonn; Institute of Human Genetics (A.E.V.), University Medical Center Hamburg-Eppendorf, Hamburg; Department of Psychiatry and Psychotherapy (J.W.), University Medical Center Göttingen; DZNE (J.W.), Göttingen, Germany; iBiMED (J.W.), Medical Sciences Department, University of Aveiro, Portugal; Clinic for Cognitive Neurology (M.L.S.), University Clinic Leipzig; and Max Planck Institute for Human Cognitive and Brain Sciences (M.L.S.), Leipzig, Germany.

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http://dx.doi.org/10.1212/WNL.0000000000006318DOI Listing
October 2018

Serum neurofilament light chain in behavioral variant frontotemporal dementia.

Neurology 2018 10 12;91(15):e1390-e1401. Epub 2018 Sep 12.

From the Department of Neurology (P.S., S.A.-S., E.S., I.U., C.A.F.v.A., J. Kassubek, B.L., P.O., A.C.L., M.O.) and Institute of Epidemiology and Medical Biometry (B.M.), University of Ulm; Department of Psychiatry and Psychotherapy (J.D.-S., H.F., T.G.), Klinikum Rechts der Isar, Technical University of Munich; Department of Nuclear Medicine (H.B.), Leipzig University Hospital; Department of Neurology (A.D.), Ludwig-Maximilians-University, Munich; Department of Neurology (K.F.), Saarland University, Homburg; Department of Psychiatry and Psychotherapy (K.F.), University of Bonn, Germany; Swiss Epilepsy Center (H.-J.H.), Zurich, Switzerland; Department of Psychiatry and Psychotherapy (H.J.), University Medical Center Hamburg-Eppendorf, Hamburg; AMEOS Klinikum (H.J.), Heiligenhafen; Department of Psychiatry and Psychotherapy (J. Kornhuber, J.M.M.), Friedrich-Alexander-University of Erlangen-Nuremberg, Erlangen; Department of Psychiatry and Psychotherapy (M.L.), University of Würzburg; Department of Neurology (J.P.), University of Rostock; DZNE (J.P.), Rostock; Department of Neurodegenerative Diseases and Geriatric Psychiatry (A.S.), University Hospital Bonn; DZNE (A.S.), Bonn; Institute of Human Genetics (A.E.V.), University Medical Center Hamburg-Eppendorf, Hamburg; Department of Psychiatry and Psychotherapy (J.W.), University Medical Center Göttingen; DZNE (J.W.), Göttingen, Germany; iBiMED (J.W.), Medical Sciences Department, University of Aveiro, Portugal; Clinic for Cognitive Neurology (M.L.S.), University Clinic Leipzig; and Max Planck Institute for Human Cognitive and Brain Sciences (M.L.S.), Leipzig, Germany.

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http://dx.doi.org/10.1212/WNL.0000000000006318DOI Listing
October 2018

Overlap between age-at-onset and disease-progression determinants in Huntington disease.

Neurology 2018 06 9;90(24):e2099-e2106. Epub 2018 May 9.

From the Department of Neurodegenerative Disease (N.A.A., S.J.T.), UCL Huntington's Disease Centre, University College London Institute of Neurology, UK; Departments of Neurology (N.A.A.) and Public Health and Primary Care (J.M.M.v.d.B.), Leiden University Medical Centre, the Netherlands; Department of Population Health Sciences (N.A.A.), German Center for Neurodegenerative Diseases (DZNE), Bonn; and Department of Neurology (G.B.L.), Ulm University Hospital, Germany.

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http://www.neurology.org/lookup/doi/10.1212/WNL.000000000000
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http://dx.doi.org/10.1212/WNL.0000000000005690DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5996832PMC
June 2018

Objective assessment of gait and posture in premanifest and manifest Huntington disease - A multi-center study.

Gait Posture 2018 05 7;62:451-457. Epub 2018 Apr 7.

Department of Neurology, University of Münster, Albert-Schweitzer Campus 1, 48149 Münster, Germany; George-Huntington-Institute, Deilmann-Building IV, Technology-Park, Johann-Krane Weg 27, 48149 Münster, Germany; Institute for Clinical Radiology, University of Münster, Albert-Schweitzer Campus 1, 48149 Münster, Germany; Department of Neurodegenerative Diseases and Hertie-Institute for Clinical Brain, Research, University of Tübingen, Tübingen, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.gaitpost.2018.03.039DOI Listing
May 2018

Survival End Points for Huntington Disease Trials Prior to a Motor Diagnosis.

JAMA Neurol 2017 11;74(11):1352-1360

Huntington's Disease Centre, Department of Neurodegenerative Disease, Institute of Neurology, University College London, Queen Square, London, England.

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http://dx.doi.org/10.1001/jamaneurol.2017.2107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5710578PMC
November 2017

Body weight is a robust predictor of clinical progression in Huntington disease.

Ann Neurol 2017 Sep 22;82(3):479-483. Epub 2017 Aug 22.

Department of Neurology, Leiden University Medical Center, Leiden, the Netherlands.

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http://dx.doi.org/10.1002/ana.25007DOI Listing
September 2017

Revisiting the Logan plot to account for non-negligible blood volume in brain tissue.

EJNMMI Res 2017 Aug 18;7(1):66. Epub 2017 Aug 18.

Department of Clinical Neuroscience, Center for Psychiatry Research, Karolinska Institutet and Stockholm County Council, Stockholm, Sweden.

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http://dx.doi.org/10.1186/s13550-017-0314-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5561763PMC
August 2017

Identification of extreme motor phenotypes in Huntington's disease.

Am J Med Genet B Neuropsychiatr Genet 2017 Apr 21;174(3):283-294. Epub 2016 Nov 21.

Department of Neurology, Ulm University, Germany.

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http://dx.doi.org/10.1002/ajmg.b.32514DOI Listing
April 2017

Neurofilament as a blood marker for diagnosis and monitoring of primary progressive aphasias.

Neurology 2017 Mar 8;88(10):961-969. Epub 2017 Feb 8.

From the Department of Neurology (P.S., E.S., S.A.-S., I.U., B.L., C.A.F.v.A., J. Kassubek, P.O., A.C.L., M.O.), University of Ulm; Department of Psychiatry and Psychotherapy (J.D.-S., H.F., C.R.), Technical University of Munich; Clinic for Cognitive Neurology (M.L.S.), University Clinic Leipzig and Max Planck Institute for Human Cognitive and Brain Sciences, Germany; Swiss Epilepsy Center (H.-J.H.), Zürich, Switzerland; Department of Neurology (K. Fassbender), Saarland University, Homburg; Department of Psychiatry and Psychotherapy (K. Fliessbach), University of Bonn and DZNE; Department of Neurology (J.P.), University of Rostock and German Center for Neurodegenerative Diseases; Department of Psychiatry and Psychotherapy (J. Kornhuber), Friedrich-Alexander-University of Erlangen-Nuremberg, Erlangen; Department of Psychiatry and Psychotherapy (A.S.), University of Göttingen; Institute of Human Genetics (A.E.V.), University Medical Center Hamburg-Eppendorf, Hamburg; Department of Psychiatry and Psychotherapy (M.L.), University of Würzburg; and Department of Neurology (A.D.), Ludwig-Maximilians-University Munich, Germany.

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http://dx.doi.org/10.1212/WNL.0000000000003688DOI Listing
March 2017

Validation of a prognostic index for Huntington's disease.

Mov Disord 2017 02 28;32(2):256-263. Epub 2016 Nov 28.

CHDI Management/CHDI Foundation, Princeton, New Jersey, USA.

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http://dx.doi.org/10.1002/mds.26838DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5318276PMC
February 2017

Eighth International Chorea-Acanthocytosis Symposium: Summary of Workshop Discussion and Action Points.

Tremor Other Hyperkinet Mov (N Y) 2017 15;7:428. Epub 2017 Feb 15.

Department of Neurology, University of Michigan, Ann Arbor, MI, USA; Neurology Service, VAAAHS, University of Michigan, Ann Arbor, MI, USA; Udall Centre, University of Michigan, Ann Arbor, MI, USA; GRECC, VAAAHS, University of Michigan, Ann Arbor, MI, USA,; Michigan Alzheimer's Disease Center, University of Michigan, Ann Arbor, MI, USA.

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http://dx.doi.org/10.7916/D8XD127WDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5313633PMC
February 2017

Corrigendum to "Neuropsychiatric symptoms are very common in premanifest and early stage Huntington's disease" [Parkinsonism Relat. Disord. 25C (2016) 58-64].

Parkinsonism Relat Disord 2016 10 25;31:161. Epub 2016 Aug 25.

Department of Neurology, Movement Disorders Unit, Hospital de la Santa Creu i Sant Pau, Universitat Aut_onoma de Barcelona, Barcelona, Spain; Sant Pau Institute of Biomedical Research (IIB-Sant Pau), Barcelona, Spain; Centro Investigaci_on Biomedica en Red-Enfermedades Neurodegenerativas (CIBERNED), Spain; Universitat Oberta de Catalunya (UOC), Barcelona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.parkreldis.2016.08.011DOI Listing
October 2016

Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis.

Authors:
Wouter van Rheenen Aleksey Shatunov Annelot M Dekker Russell L McLaughlin Frank P Diekstra Sara L Pulit Rick A A van der Spek Urmo Võsa Simone de Jong Matthew R Robinson Jian Yang Isabella Fogh Perry Tc van Doormaal Gijs H P Tazelaar Max Koppers Anna M Blokhuis William Sproviero Ashley R Jones Kevin P Kenna Kristel R van Eijk Oliver Harschnitz Raymond D Schellevis William J Brands Jelena Medic Androniki Menelaou Alice Vajda Nicola Ticozzi Kuang Lin Boris Rogelj Katarina Vrabec Metka Ravnik-Glavač Blaž Koritnik Janez Zidar Lea Leonardis Leja Dolenc Grošelj Stéphanie Millecamps François Salachas Vincent Meininger Mamede de Carvalho Susana Pinto Jesus S Mora Ricardo Rojas-García Meraida Polak Siddharthan Chandran Shuna Colville Robert Swingler Karen E Morrison Pamela J Shaw John Hardy Richard W Orrell Alan Pittman Katie Sidle Pietro Fratta Andrea Malaspina Simon Topp Susanne Petri Susanne Abdulla Carsten Drepper Michael Sendtner Thomas Meyer Roel A Ophoff Kim A Staats Martina Wiedau-Pazos Catherine Lomen-Hoerth Vivianna M Van Deerlin John Q Trojanowski Lauren Elman Leo McCluskey A Nazli Basak Ceren Tunca Hamid Hamzeiy Yesim Parman Thomas Meitinger Peter Lichtner Milena Radivojkov-Blagojevic Christian R Andres Cindy Maurel Gilbert Bensimon Bernhard Landwehrmeyer Alexis Brice Christine A M Payan Safaa Saker-Delye Alexandra Dürr Nicholas W Wood Lukas Tittmann Wolfgang Lieb Andre Franke Marcella Rietschel Sven Cichon Markus M Nöthen Philippe Amouyel Christophe Tzourio Jean-François Dartigues Andre G Uitterlinden Fernando Rivadeneira Karol Estrada Albert Hofman Charles Curtis Hylke M Blauw Anneke J van der Kooi Marianne de Visser An Goris Markus Weber Christopher E Shaw Bradley N Smith Orietta Pansarasa Cristina Cereda Roberto Del Bo Giacomo P Comi Sandra D'Alfonso Cinzia Bertolin Gianni Sorarù Letizia Mazzini Viviana Pensato Cinzia Gellera Cinzia Tiloca Antonia Ratti Andrea Calvo Cristina Moglia Maura Brunetti Simona Arcuti Rosa Capozzo Chiara Zecca Christian Lunetta Silvana Penco Nilo Riva Alessandro Padovani Massimiliano Filosto Bernard Muller Robbert Jan Stuit Ian Blair Katharine Zhang Emily P McCann Jennifer A Fifita Garth A Nicholson Dominic B Rowe Roger Pamphlett Matthew C Kiernan Julian Grosskreutz Otto W Witte Thomas Ringer Tino Prell Beatrice Stubendorff Ingo Kurth Christian A Hübner P Nigel Leigh Federico Casale Adriano Chio Ettore Beghi Elisabetta Pupillo Rosanna Tortelli Giancarlo Logroscino John Powell Albert C Ludolph Jochen H Weishaupt Wim Robberecht Philip Van Damme Lude Franke Tune H Pers Robert H Brown Jonathan D Glass John E Landers Orla Hardiman Peter M Andersen Philippe Corcia Patrick Vourc'h Vincenzo Silani Naomi R Wray Peter M Visscher Paul I W de Bakker Michael A van Es R Jeroen Pasterkamp Cathryn M Lewis Gerome Breen Ammar Al-Chalabi Leonard H van den Berg Jan H Veldink

Nat Genet 2016 09 25;48(9):1043-8. Epub 2016 Jul 25.

Department of Neurology, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, the Netherlands.

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http://dx.doi.org/10.1038/ng.3622DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5556360PMC
September 2016

Neuropsychiatric symptoms are very common in premanifest and early stage Huntington's Disease.

Parkinsonism Relat Disord 2016 Apr 11;25:58-64. Epub 2016 Feb 11.

Department of Neurology, Movement Disorders Unit, Hospital de la Santa Creu i Sant Pau, Universitat Autònoma de Barcelona, Barcelona, Spain; Sant Pau Institute of Biomedical Research (IIB-Sant Pau), Barcelona, Spain; Centro Investigación Biomedica en Red-Enfermedades Neurodegenerativas (CIBERNED), Spain; Universitat Oberta de Catalunya (UOC), Barcelona, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.parkreldis.2016.02.008DOI Listing
April 2016

Motor network structure and function are associated with motor performance in Huntington's disease.

J Neurol 2016 Mar 13;263(3):539-49. Epub 2016 Jan 13.

Department of Neurology, University of Ulm, Oberer Eselsberg 45/1, 89081, Ulm, Germany.

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http://dx.doi.org/10.1007/s00415-015-8014-yDOI Listing
March 2016

Abnormal cerebellar volume and corticocerebellar dysfunction in early manifest Huntington's disease.

J Neurol 2015 28;262(4):859-69. Epub 2015 Jan 28.

Department of Psychiatry, Psychotherapy and Psychosomatics, Saarland University, Kirrberger Str. 1, 66421, Homburg, Germany,

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http://dx.doi.org/10.1007/s00415-015-7642-6DOI Listing
January 2016

Short-interval observational data to inform clinical trial design in Huntington's disease.

J Neurol Neurosurg Psychiatry 2015 Dec 10;86(12):1291-8. Epub 2015 Feb 10.

Department of Neurodegenerative Disease, UCL Institute of Neurology, University College London, London, UK.

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http://dx.doi.org/10.1136/jnnp-2014-309768DOI Listing
December 2015

Ethyl-eicosapentaenoic acid treatment in Huntington's disease: A placebo-controlled clinical trial.

Mov Disord 2015 Sep 14;30(10):1426-9. Epub 2015 Jul 14.

Universitätsklinik Ulm, Ulm, Germany.

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http://dx.doi.org/10.1002/mds.26308DOI Listing
September 2015

Update on Huntington's disease: advances in care and emerging therapeutic options.

Parkinsonism Relat Disord 2015 Mar 19;21(3):169-78. Epub 2014 Dec 19.

Department of Neurology, University of Ulm, Ulm, Germany.

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http://dx.doi.org/10.1016/j.parkreldis.2014.12.013DOI Listing
March 2015

Neuropsychiatric symptoms in a European Huntington's disease cohort (REGISTRY).

J Neurol Neurosurg Psychiatry 2014 Dec 14;85(12):1411-8. Epub 2014 May 14.

Department of Neurology, University of Ulm, Ulm, Germany.

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http://dx.doi.org/10.1136/jnnp-2013-307343DOI Listing
December 2014

Cerebellar abnormalities in Huntington's disease: a role in motor and psychiatric impairment?

Mov Disord 2014 Nov 13;29(13):1648-54. Epub 2014 Aug 13.

University College London, Institute of Neurology, Queen Square, London, UK.

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http://dx.doi.org/10.1002/mds.25984DOI Listing
November 2014

Longitudinal task-negative network analyses in preclinical Huntington's disease.

Eur Arch Psychiatry Clin Neurosci 2014 Sep 27;264(6):493-505. Epub 2013 Sep 27.

Center for Psychosocial Medicine, Department of General Psychiatry, University of Heidelberg, Voßstraße 4, 69115, Heidelberg, Germany,

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http://dx.doi.org/10.1007/s00406-013-0447-7DOI Listing
September 2014

Visual system integrity and cognition in early Huntington's disease.

Eur J Neurosci 2014 Jul 3;40(2):2417-26. Epub 2014 Apr 3.

Department of General Psychiatry, Center for Psychosocial Medicine, University of Heidelberg, Voßstraße 4, Heidelberg, 69115, Germany.

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http://dx.doi.org/10.1111/ejn.12575DOI Listing
July 2014

Brain structure in preclinical Huntington's disease: a multi-method approach.

Neurodegener Dis 2013 17;12(1):13-22. Epub 2012 Aug 17.

Center of Psychosocial Medicine, Department of General Psychiatry, University of Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1159/000338635DOI Listing
January 2014

Longitudinal task-negative network analyses in preclinical Huntington's disease.

Eur Arch Psychiatry Clin Neurosci 2014 Sep 27;264(6):493-505. Epub 2013 Sep 27.

Center for Psychosocial Medicine, Department of General Psychiatry, University of Heidelberg, Voßstraße 4, 69115, Heidelberg, Germany,

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http://dx.doi.org/10.1007/s00406-013-0447-7DOI Listing
September 2014

One-year safety and tolerability profile of pridopidine in patients with Huntington disease.

Neurology 2013 Mar 27;80(12):1086-94. Epub 2013 Feb 27.

Centre for Neurogenetics and Rare Diseases, IRCCS Neuromed, Pozzilli, Italy.

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http://dx.doi.org/10.1212/WNL.0b013e3182886965DOI Listing
March 2013

The influence of gender on phenotype and disease progression in patients with Huntington's disease.

Parkinsonism Relat Disord 2013 Feb 25;19(2):192-7. Epub 2012 Oct 25.

Poznan University of Medical Sciences, Department of Social Medicine, Rokietnicka Str., No. 5 C, 60-806 Poznan, Poland.

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http://dx.doi.org/10.1016/j.parkreldis.2012.09.012DOI Listing
February 2013

Default-mode network changes in preclinical Huntington's disease.

Exp Neurol 2012 Sep 25;237(1):191-8. Epub 2012 Jun 25.

Center for Psychosocial Medicine, Department of General Psychiatry, University of Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.expneurol.2012.06.014DOI Listing
September 2012

Brain activation and functional connectivity in premanifest Huntington's disease during states of intrinsic and phasic alertness.

Hum Brain Mapp 2012 Sep 25;33(9):2161-73. Epub 2011 Aug 25.

Center of Psychosocial Medicine, Department of General Psychiatry, University of Heidelberg, Germany.

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http://dx.doi.org/10.1002/hbm.21348DOI Listing
September 2012

A greatly extended PPARGC1A genomic locus encodes several new brain-specific isoforms and influences Huntington disease age of onset.

Hum Mol Genet 2012 Aug 15;21(15):3461-73. Epub 2012 May 15.

Department of Laboratory Medicine, Paracelsus Medical University, Strubergasse 21, 5020 Salzburg, Austria.

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http://dx.doi.org/10.1093/hmg/dds177DOI Listing
August 2012

Quantifying change in individual subjects affected by frontotemporal lobar degeneration using automated longitudinal MRI volumetry.

Hum Brain Mapp 2012 Jul 26;33(7):1526-35. Epub 2011 May 26.

Department of Psychiatry and Psychotherapy, Center of Geriatrics and Gerontology Freiburg, Freiburg Brain Imaging, University of Freiburg, Freiburg, Germany.

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http://dx.doi.org/10.1002/hbm.21304DOI Listing
July 2012

Stability effects on results of diffusion tensor imaging analysis by reduction of the number of gradient directions due to motion artifacts: an application to presymptomatic Huntington's disease.

PLoS Curr 2011 Dec 12;3:RRN1292. Epub 2011 Dec 12.

Dept. of Neurology, University of Ulm, Ulm, Germany; Department of Neurodegenerative Disease, UCL Institute of Neurology, London, UK and Freiburg Brain Imaging, Department of Psychiatry and Psychotherapy. University of Freiburg.

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http://dx.doi.org/10.1371/currents.RRN1292DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3269342PMC
December 2011

Current Pharmacological Management in Juvenile Huntington's Disease.

PLoS Curr 2012 Feb 15;4:RRN1304. Epub 2012 Feb 15.

Department of Clinical Genetics, Sheffield Children's Hospital, Sheffield UK S10 2TH; Neurogenetics and Rare Diseases Centre, IRCCS Neuromed, Pozzilli (IS), Italy.; University of Cambridge; Department of Clinical Neurophysiology, Institute of Psychiatry and Naurology, Warsaw, Poland and Dept. of Neurology, University of Ulm, Ulm, Germany.

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http://dx.doi.org/10.1371/currents.RRN1304DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3283037PMC
February 2012

Rate of change in early Huntington's disease: a clinicometric analysis.

Mov Disord 2012 Jan 17;27(1):118-24. Epub 2011 Nov 17.

Department of Neurology, University of Ulm, Ulm, Germany.

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http://dx.doi.org/10.1002/mds.23847DOI Listing
January 2012

Huntington's disease: new aspects on phenotype and genotype.

Parkinsonism Relat Disord 2012 Jan;18 Suppl 1:S107-9

Department of Neurology, West China Hospital, Sichuan University, Sichuan, PR China.

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http://dx.doi.org/10.1016/S1353-8020(11)70034-7DOI Listing
January 2012

Stability effects on results of diffusion tensor imaging analysis by reduction of the number of gradient directions due to motion artifacts: an application to presymptomatic Huntington's disease.

PLoS Curr 2011 Dec 12;3:RRN1292. Epub 2011 Dec 12.

Dept. of Neurology, University of Ulm, Ulm, Germany; Department of Neurodegenerative Disease, UCL Institute of Neurology, London, UK and Freiburg Brain Imaging, Department of Psychiatry and Psychotherapy. University of Freiburg.

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http://dx.doi.org/10.1371/currents.RRN1292DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3269342PMC
December 2011

Longitudinal functional magnetic resonance imaging of cognition in preclinical Huntington's disease.

Exp Neurol 2011 Oct 25;231(2):214-22. Epub 2011 Jun 25.

Center of Psychosocial Medicine, Department of General Psychiatry, University of Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.expneurol.2011.06.011DOI Listing
October 2011

Magnetic resonance perfusion imaging of resting-state cerebral blood flow in preclinical Huntington's disease.

J Cereb Blood Flow Metab 2011 Sep 11;31(9):1908-18. Epub 2011 May 11.

Center of Psychosocial Medicine, Department of General Psychiatry, University of Heidelberg, Heidelberg, Germany.

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http://dx.doi.org/10.1038/jcbfm.2011.60DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3185882PMC
September 2011

Factor analysis of behavioural symptoms in Huntington's disease.

J Neurol Neurosurg Psychiatry 2011 Apr 14;82(4):411-2. Epub 2010 Apr 14.

Department of Neuropsychiatry, Birmingham and Solihull Mental Health Foundation Trust, Barberry Building, 25 Vincent Drive, Edgbaston, Birmingham B15 2FG, UK.

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http://dx.doi.org/10.1136/jnnp.2009.181149DOI Listing
April 2011

Utilisation of Healthcare and Associated Services in Huntington's disease: a data mining study.

PLoS Curr 2011 Jan 21;3:RRN1206. Epub 2011 Jan 21.

Department of Physiotherapy, Cardiff University, Ty Dewi Sant, Heath Park, Cardiff, UK; BGL Group; Health, Sport and Science, University of Glamorgan Pontypridd UK; Universitätsklinikum Ulm, Neurologie; Istitutodi Neurologia, Istituto di neurologia, Università Cattolica del Sacro Cuore, Roma, Italy and Cardiff University.

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http://dx.doi.org/10.1371/currents.RRN1206DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3034233PMC
January 2011

Genetic variants of the alpha-synuclein gene SNCA are associated with multiple system atrophy.

PLoS One 2009 Sep 22;4(9):e7114. Epub 2009 Sep 22.

MRC Centre for Neurodegeneration Research, King's College London, Department of Clinical Neuroscience, Institute of Psychiatry, and NIHR Biomedical Research Centre, London, United Kingdom.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0007114PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2743996PMC
September 2009