Publications by authors named "Bernhard Kuster"

199Publications

Radiosensitization by Kinase Inhibition Revealed by Phosphoproteomic Analysis of Pancreatic Cancer Cells.

Authors:
Svenja Wiechmann Elena Saupp Daniela Schilling Stephanie Heinzlmeir Günter Schneider Roland M Schmid Stephanie E Combs Bernhard Kuster Sophie Dobiasch

Mol Cell Proteomics 2020 Oct 25;19(10):1649-1663. Epub 2020 Nov 25.

German Cancer Consortium, Munich, Germany; German Cancer Center, Heidelberg, Germany; Department of Radiation Oncology, Technical University of Munich, Klinikum rechts der Isar, Munich, Germany; Institute of Radiation Medicine, Department of Radiation Sciences, Helmholtz Zentrum München, Neuherberg, Germany. Electronic address:

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October 2020

Combined proteomics/miRNomics of dendritic cell immunotherapy-treated glioblastoma patients as a screening for survival-associated factors.

Authors:
Friedrich Erhart Matthias Hackl Hannes Hahne Johanna Buchroithner Chen Meng Simone Klingenbrunner René Reitermaier Katrin Fischhuber Susanna Skalicky Walter Berger Sabine Spiegl-Kreinecker Daniela Lötsch Gerda Ricken Bernhard Kuster Adelheid Wöhrer Georg Widhalm Johannes Hainfellner Thomas Felzmann Alexander M Dohnal Christine Marosi Carmen Visus

NPJ Vaccines 2020 Jan 16;5(1). Epub 2020 Jan 16.

Activartis Biotech GmbH, Vienna, Austria.

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January 2020

Defining the carrier proteome limit for single-cell proteomics.

Authors:
Tommy K Cheung Chien-Yun Lee Florian P Bayer Atticus McCoy Bernhard Kuster Christopher M Rose

Nat Methods 2021 Jan 7;18(1):76-83. Epub 2020 Dec 7.

Department of Microchemistry, Proteomics and Lipidomics, Genentech, South San Francisco, CA, USA.

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January 2021

Proteomic and transcriptomic profiling of aerial organ development in Arabidopsis.

Authors:
Julia Mergner Martin Frejno Maxim Messerer Daniel Lang Patroklos Samaras Mathias Wilhelm Klaus F X Mayer Claus Schwechheimer Bernhard Kuster

Sci Data 2020 10 9;7(1):334. Epub 2020 Oct 9.

Chair of Proteomics and Bioanalytics, Technical University of Munich (TUM), Freising, Germany.

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October 2020

PROTAC-mediated degradation reveals a non-catalytic function of AURORA-A kinase.

Authors:
Bikash Adhikari Jelena Bozilovic Mathias Diebold Jessica Denise Schwarz Julia Hofstetter Martin Schröder Marek Wanior Ashwin Narain Markus Vogt Nevenka Dudvarski Stankovic Apoorva Baluapuri Lars Schönemann Lorenz Eing Pranjali Bhandare Bernhard Kuster Andreas Schlosser Stephanie Heinzlmeir Christoph Sotriffer Stefan Knapp Elmar Wolf

Nat Chem Biol 2020 11 28;16(11):1179-1188. Epub 2020 Sep 28.

Cancer Systems Biology Group, Theodor Boveri Institute, University of Würzburg, Würzburg, Germany.

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November 2020

PTPN2 Deficiency Enhances Programmed T Cell Expansion and Survival Capacity of Activated T Cells.

Authors:
Markus Flosbach Susanne G Oberle Stefanie Scherer Jana Zecha Madlaina von Hoesslin Florian Wiede Vijaykumar Chennupati Jolie G Cullen Markus List Josch K Pauling Jan Baumbach Bernhard Kuster Tony Tiganis Dietmar Zehn

Cell Rep 2020 07;32(4):107957

Division of Animal Physiology and Immunology, TUM School of Life Sciences Weihenstephan, Technical University of Munich (TUM), Freising, Germany; Division of Immunology and Allergy, Department of Medicine, Lausanne University Hospital, Lausanne, Switzerland. Electronic address:

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July 2020

Proteome activity landscapes of tumor cell lines determine drug responses.

Authors:
Martin Frejno Chen Meng Benjamin Ruprecht Thomas Oellerich Sebastian Scheich Karin Kleigrewe Enken Drecoll Patroklos Samaras Alexander Hogrebe Dominic Helm Julia Mergner Jana Zecha Stephanie Heinzlmeir Mathias Wilhelm Julia Dorn Hans-Michael Kvasnicka Hubert Serve Wilko Weichert Bernhard Kuster

Nat Commun 2020 07 20;11(1):3639. Epub 2020 Jul 20.

Chair of Proteomics and Bioanalytics, Technical University of Munich, Emil-Erlenmeyer-Forum 5, 85354, Freising, Germany.

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July 2020

Dissecting the sequence determinants for dephosphorylation by the catalytic subunits of phosphatases PP1 and PP2A.

Authors:
Bernhard Hoermann Thomas Kokot Dominic Helm Stephanie Heinzlmeir Jeremy E Chojnacki Thomas Schubert Christina Ludwig Anna Berteotti Nils Kurzawa Bernhard Kuster Mikhail M Savitski Maja Köhn

Nat Commun 2020 07 17;11(1):3583. Epub 2020 Jul 17.

Faculty of Biology, Institute of Biology III, University of Freiburg, Freiburg, Germany.

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July 2020

Radiosensitization by Kinase Inhibition Revealed by Phosphoproteomic Analysis of Pancreatic Cancer Cells.

Authors:
Svenja Wiechmann Elena Saupp Daniela Schilling Stephanie Heinzlmeir Günter Schneider Roland M Schmid Stephanie E Combs Bernhard Kuster Sophie Dobiasch

Mol Cell Proteomics 2020 10 10;19(10):1649-1663. Epub 2020 Jul 10.

German Cancer Consortium, Munich, Germany

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October 2020

Reduced mitochondrial resilience enables non-canonical induction of apoptosis after TNF receptor signaling in virus-infected hepatocytes.

Authors:
Sandra Lampl Marianne K Janas Sainitin Donakonda Marcus Brugger Kerstin Lohr Annika Schneider Katrin Manske Laura E Sperl Susan Kläger Bernhard Küster Jennifer Wettmarshausen Constanze Müller Melanie Laschinger Daniel Hartmann Norber Hüser Fabiana Perocchi Philippe Schmitt-Kopplin Franz Hagn Lars Zender Veit Hornung Christoph Borner Andreas Pichlmair Hamid Kashkar Martin Klingenspor Marco Prinz Sabrina Schreiner Marcus Conrad Philipp J Jost Hans Zischka Katja Steiger Martin Krönke Dietmar Zehn Ulrike Protzer Mathias Heikenwälder Percy A Knolle Dirk Wohlleber

J Hepatol 2020 Dec 26;73(6):1347-1359. Epub 2020 Jun 26.

Institute of Molecular Immunology and Experimental Oncology, University Hospital München rechts der Isar; Technical University of Munich, Munich, Germany.

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December 2020

Data, Reagents, Assays and Merits of Proteomics for SARS-CoV-2 Research and Testing.

Authors:
Jana Zecha Chien-Yun Lee Florian P Bayer Chen Meng Vincent Grass Johannes Zerweck Karsten Schnatbaum Thomas Michler Andreas Pichlmair Christina Ludwig Bernhard Kuster

Mol Cell Proteomics 2020 09 26;19(9):1503-1522. Epub 2020 Jun 26.

Chair of Proteomics and Bioanalytics, Technical University of Munich, Freising, Germany

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September 2020

Wnt-driven LARGE2 mediates laminin-adhesive O-glycosylation in human colonic epithelial cells and colorectal cancer.

Authors:
Vanessa Dietinger Cira R García de Durango Svenja Wiechmann Sophie L Boos Marlies Michl Jens Neumann Heiko Hermeking Bernhard Kuster Peter Jung

Cell Commun Signal 2020 06 25;18(1):102. Epub 2020 Jun 25.

German Cancer Research Center (DKFZ), Heidelberg, Germany.

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June 2020

Loss of the Fanconi anemia-associated protein NIPA causes bone marrow failure.

Authors:
Stefanie Kreutmair Miriam Erlacher Geoffroy Andrieux Rouzanna Istvanffy Alina Mueller-Rudorf Melissa Zwick Tamina Rückert Milena Pantic Teresa Poggio Khalid Shoumariyeh Tony A Mueller Hiroyuki Kawaguchi Marie Follo Cathrin Klingeberg Marcin Wlodarski Irith Baumann Dietmar Pfeifer Michal Kulinski Martina Rudelius Simone Lemeer Bernhard Kuster Christine Dierks Christian Peschel Nina Cabezas-Wallscheid Jesus Duque-Afonso Robert Zeiser Michael L Cleary Detlev Schindler Annette Schmitt-Graeff Melanie Boerries Charlotte M Niemeyer Robert Aj Oostendorp Justus Duyster Anna Lena Illert

J Clin Invest 2020 06;130(6):2827-2844

Department of Internal Medicine I, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.

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June 2020

Meltome atlas-thermal proteome stability across the tree of life.

Authors:
Anna Jarzab Nils Kurzawa Thomas Hopf Matthias Moerch Jana Zecha Niels Leijten Yangyang Bian Eva Musiol Melanie Maschberger Gabriele Stoehr Isabelle Becher Charlotte Daly Patroklos Samaras Julia Mergner Britta Spanier Angel Angelov Thilo Werner Marcus Bantscheff Mathias Wilhelm Martin Klingenspor Simone Lemeer Wolfgang Liebl Hannes Hahne Mikhail M Savitski Bernhard Kuster

Nat Methods 2020 05 13;17(5):495-503. Epub 2020 Apr 13.

Chair of Proteomics and Bioanalytics, Technical University of Munich, Freising, Germany.

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May 2020

Generating high quality libraries for DIA MS with empirically corrected peptide predictions.

Authors:
Brian C Searle Kristian E Swearingen Christopher A Barnes Tobias Schmidt Siegfried Gessulat Bernhard Küster Mathias Wilhelm

Nat Commun 2020 03 25;11(1):1548. Epub 2020 Mar 25.

Technical University of Munich, Freising, Germany.

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March 2020

A series of novel aryl-methanone derivatives as inhibitors of FMS-like tyrosine kinase 3 (FLT3) in FLT3-ITD-positive acute myeloid leukemia.

Authors:
Andreas Sellmer Bernadette Pilsl Mandy Beyer Herwig Pongratz Lukas Wirth Sigurd Elz Stefan Dove Sven Julian Henninger Karsten Spiekermann Harald Polzer Susan Klaeger Bernhard Kuster Frank D Böhmer Heinz-Herbert Fiebig Oliver H Krämer Siavosh Mahboobi

Eur J Med Chem 2020 May 13;193:112232. Epub 2020 Mar 13.

Institute of Pharmacy, Faculty of Chemistry and Pharmacy, University of Regensburg, 93040, Regensburg, Germany. Electronic address:

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May 2020

Mass-spectrometry-based draft of the Arabidopsis proteome.

Authors:
Julia Mergner Martin Frejno Markus List Michael Papacek Xia Chen Ajeet Chaudhary Patroklos Samaras Sandra Richter Hiromasa Shikata Maxim Messerer Daniel Lang Stefan Altmann Philipp Cyprys Daniel P Zolg Toby Mathieson Marcus Bantscheff Rashmi R Hazarika Tobias Schmidt Corinna Dawid Andreas Dunkel Thomas Hofmann Stefanie Sprunck Pascal Falter-Braun Frank Johannes Klaus F X Mayer Gerd Jürgens Mathias Wilhelm Jan Baumbach Erwin Grill Kay Schneitz Claus Schwechheimer Bernhard Kuster

Nature 2020 03 11;579(7799):409-414. Epub 2020 Mar 11.

Chair of Proteomics and Bioanalytics, Technical University of Munich (TUM), Freising, Germany.

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March 2020

Identification of molecular targets for the targeted treatment of gastric cancer using dasatinib.

Authors:
Raquel Carvalho Montenegro Alison Howarth Alessandro Ceroni Vita Fedele Batoul Farran Felipe Pantoja Mesquita Martin Frejno Benedict-Tilman Berger Stephanie Heinzlmeir Heba Z Sailem Roberta Tesch Daniel Ebner Stefan Knapp Rommel Burbano Bernhard Kuster Susanne Müller

Oncotarget 2020 Feb 4;11(5):535-549. Epub 2020 Feb 4.

Structural Genomics Consortium, Buchmann Institute for Life Sciences, Goethe-University Frankfurt, Frankfurt, Germany.

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February 2020

Proteomic and Metabolite Profiling Reveals Profound Structural and Metabolic Reorganization of Adipocyte Mitochondria in Obesity.

Authors:
Theresa Schöttl Fiona Pachl Pieter Giesbertz Hannelore Daniel Bernhard Kuster Tobias Fromme Martin Klingenspor

Obesity (Silver Spring) 2020 03 7;28(3):590-600. Epub 2020 Feb 7.

Chair of Molecular Nutritional Medicine, TUM School of Life Sciences Weihenstephan, Technical University of Munich, Freising, Germany.

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March 2020

Localized Inhibition of Protein Phosphatase 1 by NUAK1 Promotes Spliceosome Activity and Reveals a MYC-Sensitive Feedback Control of Transcription.

Authors:
Giacomo Cossa Isabelle Roeschert Florian Prinz Apoorva Baluapuri Raphael Silveira Vidal Christina Schülein-Völk Yun-Chien Chang Carsten Patrick Ade Guido Mastrobuoni Cyrille Girard Lars Wortmann Susanne Walz Reinhard Lührmann Stefan Kempa Bernhard Kuster Elmar Wolf Dominik Mumberg Martin Eilers

Mol Cell 2020 03 31;77(6):1322-1339.e11. Epub 2020 Jan 31.

Department of Biochemistry and Molecular Biology, Biocenter, University of Würzburg, Am Hubland, 97074 Würzburg, Germany. Electronic address:

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March 2020