Bernhard Gentner

Bernhard Gentner

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Bernhard Gentner

Bernhard Gentner

Publications by authors named "Bernhard Gentner"

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In Vivo Selection for Gene-Corrected HSPCs Advances Gene Therapy for a Rare Stem Cell Disease.

Cell Stem Cell 2019 Nov;25(5):592-593

San Raffaele Telethon Institute for Gene Therapy, Milan, Italy; Vita Salute San Raffaele University, Milan, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2019.10.004DOI Listing
November 2019

Acute myeloid leukaemia niche regulates response to L-asparaginase.

Br J Haematol 2019 Aug 1;186(3):420-430. Epub 2019 May 1.

M. Tettamanti Research Centre, Department of Paediatrics, University of Milano-Bicocca, Monza, Italy.

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http://dx.doi.org/10.1111/bjh.15920DOI Listing
August 2019

Gene therapy for mucopolysaccharidoses: in vivo and ex vivo approaches.

Ital J Pediatr 2018 Nov 16;44(Suppl 2):130. Epub 2018 Nov 16.

San Raffaele Telethon Institute for Gene Therapy (SR-TIGET), IRCCS San Raffaele Scientific Institute, Via Olgettina, 60, 20123, Milan, Italy.

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https://ijponline.biomedcentral.com/articles/10.1186/s13052-
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http://dx.doi.org/10.1186/s13052-018-0565-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238250PMC
November 2018

Dynamic Activity of miR-125b and miR-93 during Murine Neural Stem Cell Differentiation In Vitro and in the Subventricular Zone Neurogenic Niche.

PLoS One 2013 27;8(6):e67411. Epub 2013 Jun 27.

San Raffaele Scientific Institute, Telethon Institute for Gene Therapy (TIGET), Milano, Italy ; Department of Experimental Medicine and Biochemical Sciences, Section of Biochemistry and Molecular Biology, University of Perugia, Perugia, Italy.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0067411PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694868PMC
October 2017

Efficient Ex Vivo Engineering and Expansion of Highly Purified Human Hematopoietic Stem and Progenitor Cell Populations for Gene Therapy.

Stem Cell Reports 2017 04 16;8(4):977-990. Epub 2017 Mar 16.

San Raffaele Telethon Institute for Gene Therapy (SR-TIGET), Milan 20132, Italy; Hematology and Bone Marrow Transplantation Unit, IRCSS Ospedale San Raffaele, Milan 20132, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.stemcr.2017.02.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5390102PMC
April 2017

Design of a regulated lentiviral vector for hematopoietic stem cell gene therapy of globoid cell leukodystrophy.

Mol Ther Methods Clin Dev 2015 14;2:15038. Epub 2015 Oct 14.

San Raffaele Telethon Institute for Gene Therapy , San Raffaele Scientific Institute , Milan, Italy ; Vita-Salute San Raffaele University , Milan, Italy.

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http://dx.doi.org/10.1038/mtm.2015.38DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4605225PMC
October 2015

Dual-regulated lentiviral vector for gene therapy of X-linked chronic granulomatosis.

Mol Ther 2014 Aug 29;22(8):1472-1483. Epub 2014 May 29.

Department of Pediatrics, Children's Hospital Bambino Gesù and University of Rome Tor Vergata School of Medicine, Rome, Italy; San Raffaele Telethon Institute for Gene Therapy (TIGET), Scientific Institute HS Raffaele, Milan, Italy. Electronic address:

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http://dx.doi.org/10.1038/mt.2014.87DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4435596PMC
August 2014

microRNA-125 distinguishes developmentally generated and adult-born olfactory bulb interneurons.

Development 2014 Apr 5;141(7):1580-8. Epub 2014 Mar 5.

Laboratory of Molecular Neurogenetics, Department of Experimental Medical Science, Wallenberg Neuroscience Center and Lund Stem Cell Center, Lund University, 221 84 Lund, Sweden.

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http://dx.doi.org/10.1242/dev.101659DOI Listing
April 2014

A role for miR-155 in enabling tumor-infiltrating innate immune cells to mount effective antitumor responses in mice.

Blood 2013 Jul 13;122(2):243-52. Epub 2013 Mar 13.

San Raffaele Telethon Institute for Gene Therapy and Division of Regenerative Medicine, Gene Therapy and Stem Cells, San Raffaele Scientific Institute, Via Olgettina 58, Milan, Italy.

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http://dx.doi.org/10.1182/blood-2012-08-449306DOI Listing
July 2013

A double-switch vector system positively regulates transgene expression by endogenous microRNA expression (miR-ON vector).

Mol Ther 2013 May 26;21(5):934-46. Epub 2013 Feb 26.

Division of Regenerative Medicine, Gene Therapy and Stem Cells, San Raffaele Scientific Institute, Milan, Italy.

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http://dx.doi.org/10.1038/mt.2013.12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3666624PMC
May 2013

Attenuation of miR-126 activity expands HSC in vivo without exhaustion.

Cell Stem Cell 2012 Dec 8;11(6):799-811. Epub 2012 Nov 8.

Campbell Family Institute, Ontario Cancer Institute, Princess Margaret Cancer Centre, University Health Network, Toronto, ON M5G 1L7, Canada.

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http://dx.doi.org/10.1016/j.stem.2012.09.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517970PMC
December 2012

MicroRNA-124 is a subventricular zone neuronal fate determinant.

J Neurosci 2012 Jun;32(26):8879-89

Department of Experimental Medical Science, Wallenberg Neuroscience Center and Lund Stem Cell Center, Lund University, 22184 Lund, Sweden.

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http://dx.doi.org/10.1523/JNEUROSCI.0558-12.2012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4434222PMC
June 2012

A microRNA-based system for selecting and maintaining the pluripotent state in human induced pluripotent stem cells.

Stem Cells 2011 Nov;29(11):1684-95

Division of Neuroscience, Stem Cells and Neurogenesis Unit, San Raffaele Scientific Institute, Milan, Italy.

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http://dx.doi.org/10.1002/stem.726DOI Listing
November 2011

The galactocerebrosidase enzyme contributes to the maintenance of a functional hematopoietic stem cell niche.

Blood 2010 Sep 28;116(11):1857-66. Epub 2010 May 28.

San Raffaele Telethon Institute for Gene Therapy, San Raffaele Scientific Institute, Via Olgettina 58, Milan, Italy.

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http://dx.doi.org/10.1182/blood-2009-12-256461DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3173985PMC
September 2010

Tracking differentiating neural progenitors in pluripotent cultures using microRNA-regulated lentiviral vectors.

Proc Natl Acad Sci U S A 2010 Jun 7;107(25):11602-7. Epub 2010 Jun 7.

Department of Experimental Medical Sciences, Wallenberg Neuroscience Center, Lund University, 221 84 Lund, Sweden.

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http://dx.doi.org/10.1073/pnas.1006568107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2895063PMC
June 2010

Stable knockdown of microRNA in vivo by lentiviral vectors.

Nat Methods 2009 Jan 30;6(1):63-6. Epub 2008 Nov 30.

San Raffaele Telethon Institute for Gene Therapy, Via Olgettina 58, Milan, Italy.

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http://dx.doi.org/10.1038/nmeth.1277DOI Listing
January 2009

Endogenous microRNA can be broadly exploited to regulate transgene expression according to tissue, lineage and differentiation state.

Nat Biotechnol 2007 Dec 16;25(12):1457-67. Epub 2007 Nov 16.

San Raffaele Telethon Institute for Gene Therapy, San Raffaele Scientific Institute, via Olgettina, 58, 20132 Milan, Italy.

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http://dx.doi.org/10.1038/nbt1372DOI Listing
December 2007

Perioperative complications in patients undergoing major liver resection with or without neoadjuvant chemotherapy.

J Gastrointest Surg 2003 Dec;7(8):1082-8

Department of Surgical Oncology, The University of Texas M.D. Anderson Cancer Center, Houston, Texas 77030, USA.

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http://link.springer.com/content/pdf/10.1016/j.gassur.2003.0
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http://dx.doi.org/10.1016/j.gassur.2003.08.005DOI Listing
December 2003

Retroviral vector integration occurs in preferred genomic targets of human bone marrow-repopulating cells.

Blood 2003 Mar 7;101(6):2191-8. Epub 2002 Nov 7.

German Cancer Research Center, Research Program Diagnostics and Experimental Therapy, Heidelberg, Germany.

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http://dx.doi.org/10.1182/blood-2002-02-0627DOI Listing
March 2003