Publications by authors named "Bernett Lee"

100Publications

Monocytic Myeloid-Derived Suppressor Cells Underpin Resistance to Adoptive T Cell Therapy in Nasopharyngeal Carcinoma.

Mol Ther 2020 Sep 30. Epub 2020 Sep 30.

Institute of Molecular and Cell Biology, A∗STAR, Singapore 138673, Singapore; Tessa Therapeutics, Singapore 038982, Singapore; Institute of Biomedical Studies, Baylor University, Waco, TX 76712, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ymthe.2020.09.040DOI Listing
September 2020

Systematic analysis of disease-specific immunological signatures in patients with febrile illness from Saudi Arabia.

Clin Transl Immunology 2020 22;9(8):e1163. Epub 2020 Aug 22.

Singapore Immunology Network Agency for Science, Technology and Research (ASTAR) Singapore.

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http://dx.doi.org/10.1002/cti2.1163DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7443187PMC
August 2020

Linear B-cell epitopes in the spike and nucleocapsid proteins as markers of SARS-CoV-2 exposure and disease severity.

EBioMedicine 2020 Aug 22;58:102911. Epub 2020 Jul 22.

Infectious Diseases Horizontal Technology Centre (ID HTC), Agency for Science, Technology and Research (A*STAR), 8A Biomedical Grove, Immunos #04-06, Biopolis, Singapore 138648, Singapore; Laboratory of Microbial Immunity, Singapore Immunology Network, Agency for Science, Technology and Research (A*STAR), 8A Biomedical Grove, Immunos #04-06, Biopolis, Singapore 138648, Singapore; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore; National Institute of Health Research, Health Protection Research Unit in Emerging and Zoonotic Infections, University of Liverpool, Liverpool, United Kingdom; Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2020.102911DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7375792PMC
August 2020

Macrophage polarisation associated with atherosclerosis differentially affects their capacity to handle lipids.

Atherosclerosis 2020 07 10;305:10-18. Epub 2020 Jun 10.

Department of Infection, Immunity & Cardiovascular Disease, University of Sheffield, Beech Hill Road, Sheffield, S10 2RX, UK. Electronic address:

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http://dx.doi.org/10.1016/j.atherosclerosis.2020.05.003DOI Listing
July 2020

Combinatorial Single-Cell Analyses of Granulocyte-Monocyte Progenitor Heterogeneity Reveals an Early Uni-potent Neutrophil Progenitor.

Immunity 2020 Aug 23;53(2):303-318.e5. Epub 2020 Jun 23.

Singapore Immunology Network (SIgN), A∗STAR (Agency for Science, Technology and Research), Biopolis, Singapore 138648, Singapore; School of Biological Sciences, Nanyang Technological University, Singapore 637551, Singapore; Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore 117545, Singapore; State Key Laboratory of Experimental Hematology, Institute of Hematology, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin 300020, China; National Cancer Centre Singapore, Singapore 169610, Singapore. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2020.06.005DOI Listing
August 2020

Large-Scale HLA Tetramer Tracking of T Cells during Dengue Infection Reveals Broad Acute Activation and Differentiation into Two Memory Cell Fates.

Immunity 2019 12 19;51(6):1119-1135.e5. Epub 2019 Nov 19.

Singapore Immunology Network, Agency for Science, Technology and Research, Singapore 138648, Singapore; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2019.10.007DOI Listing
December 2019

Single-Cell Analysis of Human Mononuclear Phagocytes Reveals Subset-Defining Markers and Identifies Circulating Inflammatory Dendritic Cells.

Immunity 2019 09 29;51(3):573-589.e8. Epub 2019 Aug 29.

Singapore Immunology Network, A(∗)STAR, 8A Biomedical Grove, Immunos Building, Singapore 138648, Singapore; Translational Immunology Institute, Singhealth/Duke-NUS Academic Medical Centre, the Academia, 20 College Road, Discovery Tower Level 8, Singapore 169856, Singapore. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2019.08.008DOI Listing
September 2019

Evaluation of phospho-histone H3 in Asian triple-negative breast cancer using multiplex immunofluorescence.

Breast Cancer Res Treat 2019 Nov 13;178(2):295-305. Epub 2019 Aug 13.

Division of Pathology, Singapore General Hospital, 20 College Road, Singapore, 169856, Singapore.

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http://dx.doi.org/10.1007/s10549-019-05396-5DOI Listing
November 2019

The role of Ki-67 in Asian triple negative breast cancers: a novel combinatory panel approach.

Virchows Arch 2019 Dec 12;475(6):709-725. Epub 2019 Aug 12.

Division of Pathology, Singapore General Hospital, 20 College Road, Academia, Level 7, Diagnostics Tower, Singapore, 169856, Singapore.

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http://dx.doi.org/10.1007/s00428-019-02635-4DOI Listing
December 2019

Oxygen-Mediated Control of the Keratinocyte Proliferation-Differentiation Axis.

J Invest Dermatol 2020 01 5;140(1):235-238.e3. Epub 2019 Jul 5.

Skin Research Institute of Singapore, Singapore; Institute of Medical Biology, Singapore. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2019.05.030DOI Listing
January 2020

Detection and characterization of a novel marine birnavirus isolated from Asian seabass in Singapore.

Virol J 2019 05 28;16(1):71. Epub 2019 May 28.

Centre for Animal & Veterinary Sciences, Professional and Scientific Services, Animal and Veterinary Service, National Parks Board (NParks), 1 Cluny Road, Singapore, 259569, Singapore.

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http://dx.doi.org/10.1186/s12985-019-1174-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6537170PMC
May 2019

Canine Parvovirus-2c (CPV-2c) Infection in Wild Asian Palm Civets () in Singapore.

J Wildl Dis 2019 10 28;55(4):965-969. Epub 2019 Mar 28.

Animal and Plant Health Center, Virology Section, Animal Health Laboratory Department, Laboratories Group, Agri-Food and Veterinary Authority, 6 Perahu Road, Singapore 718827.

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October 2019

RNA-Seq Signatures Normalized by mRNA Abundance Allow Absolute Deconvolution of Human Immune Cell Types.

Cell Rep 2019 02;26(6):1627-1640.e7

Singapore Immunology Network (SIgN), Agency for Science Technology and Research, Biopolis, 8A Biomedical Grove, 138648, Singapore, Singapore; Department of Biology, Faculty of Sciences, University Tunis El Manar, Tunis, Tunisia; Faculty of Medicine, University of Sherbrooke, Sherbrooke, QC, Canada; Department of Microbiology, Immunology Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.01.041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367568PMC
February 2019

Mapping of γ/δ T cells reveals Vδ2+ T cells resistance to senescence.

EBioMedicine 2019 Jan 7;39:44-58. Epub 2018 Dec 7.

Singapore Immunology Network (SIgN), Agency for Science Technology and Research (A*STAR), Immunos Building, Singapore 138648, Singapore; School of Biological Sciences, Nanyang Technological University, Singapore, Singapore; Department of Microbiology, National University of Singapore, Singapore, Singapore; Department of Biology, Faculty of Science, University Tunis El Manar, Tunis, Tunisia. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2018.11.053DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6354624PMC
January 2019

3-Dimensional Optical Clearing and Imaging of Pruritic Atopic Dermatitis and Psoriasis Skin Reveals Downregulation of Epidermal Innervation.

J Invest Dermatol 2019 05 22;139(5):1201-1204. Epub 2018 Nov 22.

National Skin Centre, Singapore; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2018.11.006DOI Listing
May 2019

Zika Virus Infects Human Fetal Brain Microglia and Induces Inflammation.

Clin Infect Dis 2017 Apr;64(7):914-920

Singapore Immunology Network, Agency for Science, Technology and Research (A*STAR).

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https://academic.oup.com/cid/article/3041121/Zika
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http://dx.doi.org/10.1093/cid/ciw878DOI Listing
April 2017

Higher densities of Foxp3 regulatory T cells are associated with better prognosis in triple-negative breast cancer.

Breast Cancer Res Treat 2017 May 23;163(1):21-35. Epub 2017 Feb 23.

Division of Pathology, Singapore General Hospital, 20 College Road, Academia, Level 10, Diagnostics Tower, Singapore, 169856, Singapore.

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http://dx.doi.org/10.1007/s10549-017-4161-4DOI Listing
May 2017

Neuropeptide Y associated with asthma in young adults.

Neuropeptides 2016 Oct 20;59:117-121. Epub 2016 Jul 20.

Department of Psychological Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01434179163001
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http://dx.doi.org/10.1016/j.npep.2016.07.003DOI Listing
October 2016

Systematic characterization of basophil anergy.

Allergy 2017 Mar 8;72(3):373-384. Epub 2016 Aug 8.

Singapore Immunology Network (SIgN), A*STAR (Agency for Science, Technology and Research), Singapore, Singapore.

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http://dx.doi.org/10.1111/all.12952DOI Listing
March 2017

Neutrophils Self-Regulate Immune Complex-Mediated Cutaneous Inflammation through CXCL2.

J Invest Dermatol 2016 Feb;136(2):416-424

Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), Biopolis, Singapore; School of Biological Sciences, Nanyang Technological University, Singapore. Electronic address:

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http://dx.doi.org/10.1038/JID.2015.410DOI Listing
February 2016

RNA sensing by conventional dendritic cells is central to the development of lupus nephritis.

Proc Natl Acad Sci U S A 2015 Nov 28;112(45):E6195-204. Epub 2015 Oct 28.

Singapore Immunology Network, A*STAR, 138648 Singapore; Department of Immunology, University of Texas Southwestern Medical Center, Dallas, TX 75390-9093; School of Biological Sciences, Nanyang Technological University, 637551 Singapore;

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http://dx.doi.org/10.1073/pnas.1507052112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4653170PMC
November 2015

Functional variants of 17q12-21 are associated with allergic asthma but not allergic rhinitis.

J Allergy Clin Immunol 2016 Mar 23;137(3):758-66.e3. Epub 2015 Oct 23.

Department of Biological Sciences, National University of Singapore, Singapore. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2015.08.038DOI Listing
March 2016

CD103(+) Dendritic Cells Control Th17 Cell Function in the Lung.

Cell Rep 2015 Sep 10;12(11):1789-801. Epub 2015 Sep 10.

Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A(∗)STAR), Singapore 138648, Singapore. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2015.08.030DOI Listing
September 2015

Dendritic cell derived IL-2 inhibits survival of terminally mature cells via an autocrine signaling pathway.

Eur J Immunol 2015 May 18;45(5):1494-9. Epub 2015 Mar 18.

Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.

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http://dx.doi.org/10.1002/eji.201445050DOI Listing
May 2015

A Systematic Meta-analysis of Immune Signatures in Patients With Acute Chikungunya Virus Infection.

J Infect Dis 2015 Jun 29;211(12):1925-35. Epub 2015 Jan 29.

Singapore Immunology Network, Agency for Science, Technology and Research (A*STAR), Biopolis Institute of Infection and Global Health, University of Liverpool, United Kingdom.

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http://dx.doi.org/10.1093/infdis/jiv049DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4442625PMC
June 2015

Visualization of bone marrow monocyte mobilization using Cx3cr1gfp/+Flt3L-/- reporter mouse by multiphoton intravital microscopy.

J Leukoc Biol 2015 Mar 16;97(3):611-9. Epub 2014 Dec 16.

*Singapore Immunology Network, Agency for Science, Technology and Research, Biopolis, Singapore; and School of Biological Sciences, Nanyang Technological University, Singapore

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http://dx.doi.org/10.1189/jlb.1TA0514-274RDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5477888PMC
March 2015

Human plasmacytoid dendritic cells regulate IFN-α production through activation-induced splicing of IL-18Rα.

J Leukoc Biol 2014 Dec 28;96(6):1037-46. Epub 2014 Aug 28.

Singapore Immunology Network and Institute of Molecular and Cell Biology, Agency for Science, Technology and Research, Biopolis, Singapore; Institute of Biomedical Studies, Baylor University, Waco, Texas, USA

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http://dx.doi.org/10.1189/jlb.2A0813-465RRDOI Listing
December 2014

Parallel T-cell cloning and deep sequencing of human MAIT cells reveal stable oligoclonal TCRβ repertoire.

Nat Commun 2014 May 15;5:3866. Epub 2014 May 15.

1] Experimental Immunology, Department of Biomedicine, University Hospital Basel, 4031 Basel, Switzerland [2] SIgN, Singapore Immunology Network, Agency for Science, Technology and Research, Singapore 138648, Singapore.

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http://dx.doi.org/10.1038/ncomms4866DOI Listing
May 2014

Cytokine analysis of aqueous humor in HIV patients with cytomegalovirus retinitis.

Cytokine 2013 Nov 3;64(2):541-7. Epub 2013 Sep 3.

National Healthcare Group Eye Institute, Tan Tock Seng Hospital, Singapore; Singapore National Eye Center, Singapore.

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http://dx.doi.org/10.1016/j.cyto.2013.08.006DOI Listing
November 2013

Optimal cellular preservation for high dimensional flow cytometric analysis of multicentre trials.

J Immunol Methods 2012 Nov 24;385(1-2):79-89. Epub 2012 Aug 24.

Singapore Immunology Network, Agency for Science, Technology and Research, 8A Biomedical Grove, Immunos Building, Level 3, Biopolis 138648, Singapore.

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http://dx.doi.org/10.1016/j.jim.2012.08.010DOI Listing
November 2012

Cistrome: an integrative platform for transcriptional regulation studies.

Genome Biol 2011 Aug 22;12(8):R83. Epub 2011 Aug 22.

Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute and Harvard School of Public Health, Boston, MA 02215, USA.

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http://genomebiology.biomedcentral.com/articles/10.1186/gb-2
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http://dx.doi.org/10.1186/gb-2011-12-8-r83DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3245621PMC
August 2011

The transcription factor Runx3 represses the neurotrophin receptor TrkB during lineage commitment of dorsal root ganglion neurons.

J Biol Chem 2007 Aug 20;282(33):24175-84. Epub 2007 Jun 20.

Institute of Molecular and Cell Biology, Singapore 13 8673.

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http://dx.doi.org/10.1074/jbc.M703746200DOI Listing
August 2007

ASGS: an alternative splicing graph web service.

Nucleic Acids Res 2006 Jul;34(Web Server issue):W444-7

Department of Chemistry and Biomolecular Sciences and Biotechnology Research Institute, Macquarie University, Sydney, NSW 2109, Australia.

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http://dx.doi.org/10.1093/nar/gkl268DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1538904PMC
July 2006

Genome-scale analysis of positional clustering of mouse testis-specific genes.

BMC Genomics 2005 Jan 19;6. Epub 2005 Jan 19.

Institute for Infocomm Research, Heng Mui Keng Terrace 21, Singapore.

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http://dx.doi.org/10.1186/1471-2164-6-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC548148PMC
January 2005