Bernd Timmermann

Bernd Timmermann

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Bernd Timmermann

Bernd Timmermann

Publications by authors named "Bernd Timmermann"

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78Publications

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Papillary Renal Cell Carcinomas Rewire Glutathione Metabolism and Are Deficient in Both Anabolic Glucose Synthesis and Oxidative Phosphorylation.

Cancers (Basel) 2019 Sep 3;11(9). Epub 2019 Sep 3.

Max Planck Institute for Molecular Genetics, Mass Spectrometry Facility, Ihnestrasse 63-73, 14195 Berlin, Germany.

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http://dx.doi.org/10.3390/cancers11091298DOI Listing
September 2019

Differential Interleukin-2 Transcription Kinetics Render Mouse but Not Human T Cells Vulnerable to Splicing Inhibition Early after Activation.

Mol Cell Biol 2019 Aug 29;39(16). Epub 2019 Jul 29.

Institute of Chemistry and Biochemistry, Laboratory of RNA Biochemistry, Freie Universität Berlin, Berlin, Germany

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http://dx.doi.org/10.1128/MCB.00035-19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6664609PMC
August 2019

Increased versatility despite reduced molecular complexity: evolution, structure and function of metazoan splicing factor PRPF39.

Nucleic Acids Res 2019 Jun;47(11):5867-5879

Institut für Chemie und Biochemie, RNA Biochemie, Freie Universität Berlin, Takustr. 6, 14195 Berlin, Germany.

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http://dx.doi.org/10.1093/nar/gkz243DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582350PMC
June 2019

Mitigating Anticipated Effects of Systematic Errors Supports Sister-Group Relationship between Xenacoelomorpha and Ambulacraria.

Curr Biol 2019 Jun 16;29(11):1818-1826.e6. Epub 2019 May 16.

Centre for Life's Origins and Evolution, Department of Genetics, Evolution and Environment, University College London, Darwin Building, Gower Street, London WC1E 6BT, UK; Department of Computer Science, University College London, Darwin Building, Gower Street, London WC1E 6BT, UK. Electronic address:

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http://dx.doi.org/10.1016/j.cub.2019.04.009DOI Listing
June 2019

Ice-Age Climate Adaptations Trap the Alpine Marmot in a State of Low Genetic Diversity.

Curr Biol 2019 May 9;29(10):1712-1720.e7. Epub 2019 May 9.

Molecular Biology of Metabolism Laboratory, The Francis Crick Institute, 1 Midland Road, London NW1 1AT, UK; Department of Biochemistry and Cambridge Systems Biology Centre, University of Cambridge, 80 Tennis Court Road, Cambridge CB2 1GA, UK; Department of Biochemistry, Charitè, Am Chariteplatz 1, 10117 Berlin, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.cub.2019.04.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6538971PMC
May 2019

Esrrb Unlocks Silenced Enhancers for Reprogramming to Naive Pluripotency.

Cell Stem Cell 2018 Aug 14;23(2):266-275.e6. Epub 2018 Jun 14.

Department of Cell and Developmental Biology, Max Planck Institute for Molecular Biomedicine, 48149 Münster, Germany; Medical Faculty, University of Münster, 48149 Münster, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2018.05.020DOI Listing
August 2018

Genome-wide strategies identify downstream target genes of chick connective tissue-associated transcription factors.

Development 2018 03 29;145(7). Epub 2018 Mar 29.

Freie Universität Berlin, Institute of Chemistry and Biochemistry, Thielallee 63, 14195 Berlin, Germany

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http://dx.doi.org/10.1242/dev.161208DOI Listing
March 2018

A dual transcript-discovery approach to improve the delimitation of gene features from RNA-seq data in the chicken model.

Biol Open 2018 Jan 17;7(1). Epub 2018 Jan 17.

Freie Universität Berlin, Institut für Chemie und Biochemie, Thielallee 63, 14195 Berlin, Germany

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http://dx.doi.org/10.1242/bio.028498DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5827264PMC
January 2018

The cancer-associated U2AF35 470A>G (Q157R) mutation creates an in-frame alternative 5' splice site that impacts splicing regulation in Q157R patients.

RNA 2017 12 11;23(12):1796-1806. Epub 2017 Sep 11.

Freie Universität Berlin, Institute of Chemistry and Biochemistry, Laboratory of RNA Biochemistry, 14195 Berlin, Germany.

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http://dx.doi.org/10.1261/rna.061432.117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689001PMC
December 2017

Protein interaction perturbation profiling at amino-acid resolution.

Nat Methods 2017 Dec 16;14(12):1213-1221. Epub 2017 Oct 16.

Otto-Warburg Laboratory, Max-Planck Institute for Molecular Genetics (MPIMG), Berlin, Germany.

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http://dx.doi.org/10.1038/nmeth.4464DOI Listing
December 2017

Antagonistic Activities of Sox2 and Brachyury Control the Fate Choice of Neuro-Mesodermal Progenitors.

Dev Cell 2017 09 17;42(5):514-526.e7. Epub 2017 Aug 17.

Department of Developmental Genetics, Max Planck Institute for Molecular Genetics, Ihnestr. 63-73, 14195 Berlin, Germany; Institute for Medical Genetics, Charité - University Medicine Berlin, Campus Benjamin Franklin, Hindenburgdamm 30, 12203 Berlin, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.devcel.2017.07.021DOI Listing
September 2017

Haplotype-resolved sweet potato genome traces back its hexaploidization history.

Nat Plants 2017 Sep 21;3(9):696-703. Epub 2017 Aug 21.

Department of Computational Molecular Biology, Max Planck Institute for Molecular Genetics, Ihnestraße 63-73, 14195, Berlin, Germany.

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http://dx.doi.org/10.1038/s41477-017-0002-zDOI Listing
September 2017

Patterning and gastrulation defects caused by the lethal are due to loss of .

Biol Open 2017 Jun 15;6(6):752-764. Epub 2017 Jun 15.

Max Planck Institute for Molecular Genetics, Department Developmental Genetics, Ihnestraße 63-73, Berlin 14195, Germany

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http://bio.biologists.org/lookup/doi/10.1242/bio.023200
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http://dx.doi.org/10.1242/bio.023200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5483016PMC
June 2017

The bromodomain protein BRD4 regulates splicing during heat shock.

Nucleic Acids Res 2017 Jan 17;45(1):382-394. Epub 2016 Aug 17.

Department of Vertebrate Genomics, Max Planck Institute for Molecular Genetics, Ihnestr.63-73, 14195 Berlin, Germany

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http://dx.doi.org/10.1093/nar/gkw729DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5224492PMC
January 2017

Characterization of the genome and transcriptome of the blue tit Cyanistes caeruleus: polymorphisms, sex-biased expression and selection signals.

Mol Ecol Resour 2016 03 10;16(2):549-61. Epub 2015 Aug 10.

Department of Behavioural Ecology & Evolutionary Genetics, Max Planck Institute for Ornithology, 82319 Seewiesen, Germany.

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http://dx.doi.org/10.1111/1755-0998.12450DOI Listing
March 2016

Combined ultra-low input mRNA and whole-genome sequencing of human embryonic stem cells.

BMC Genomics 2015 Nov 12;16:925. Epub 2015 Nov 12.

Department of Vertebrate Genomics, Max Planck Institute for Molecular Genetics, Ihnestr. 63-73, 14195, Berlin, Germany.

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http://dx.doi.org/10.1186/s12864-015-2025-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4643517PMC
November 2015

Effects of different oocyte retrieval and in vitro maturation systems on bovine embryo development and quality.

Zygote 2015 Jun 15;23(3):367-77. Epub 2014 Jan 15.

Institute of Farm Animal Genetics,Biotechnology,Friedrich-Loeffler-Institut (FLI),Mariensee,Höltystraße 10,Mariensee,31535 Neustadt,Germany.

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http://dx.doi.org/10.1017/S0967199413000658DOI Listing
June 2015

Disruptions of topological chromatin domains cause pathogenic rewiring of gene-enhancer interactions.

Cell 2015 May 7;161(5):1012-1025. Epub 2015 May 7.

Max Planck Institute for Molecular Genetics, RG Development & Disease, 14195 Berlin, Germany; Institute for Medical and Human Genetics, Charité Universitätsmedizin Berlin, 13353 Berlin, Germany; Berlin-Brandenburg Center for Regenerative Therapies (BCRT), Charité Universitätsmedizin Berlin, 13353 Berlin, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2015.04.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4791538PMC
May 2015

Rare and private variations in neural crest, apoptosis and sarcomere genes define the polygenic background of isolated Tetralogy of Fallot.

Hum Mol Genet 2014 Jun 23;23(12):3115-28. Epub 2014 Jan 23.

Group of Cardiovascular Genetics, Department of Vertebrate Genomics and Cardiovascular Genetics, Experimental and Clinical Research Center, Charité-Universitätsmedizin Berlin and Max Delbrück Center (MDC) for Molecular Medicine, Berlin 13125, Germany Department of Biology, Chemistry and Pharmacy, Free University of Berlin, Berlin 14195, Germany

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http://dx.doi.org/10.1093/hmg/ddu021DOI Listing
June 2014

The tissue-specific transcriptomic landscape of the mid-gestational mouse embryo.

Development 2014 Jun 6;141(11):2325-30. Epub 2014 May 6.

Department of Developmental Genetics, Max-Planck-Institute for Molecular Genetics, Ihnestrasse 63-73, 14195 Berlin, Germany Institute for Medical Genetics, Charité - University Medicine Berlin, Campus Benjamin Franklin, Hindenburgdamm 30, 12203 Berlin, Germany

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http://dx.doi.org/10.1242/dev.105858DOI Listing
June 2014

Genomics and epigenomics: new promises of personalized medicine for cancer patients.

Brief Funct Genomics 2013 Sep 28;12(5):411-21. Epub 2013 Jun 28.

Max Planck Institute for Molecular Genetics, Ihnestraße 63-73, 14195 Berlin, Germany. Tel.: +49 30 84131339; Fax: +49 30 84131380;

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http://dx.doi.org/10.1093/bfgp/elt024DOI Listing
September 2013

A Y2H-seq approach defines the human protein methyltransferase interactome.

Nat Methods 2013 Apr 3;10(4):339-42. Epub 2013 Mar 3.

Otto-Warburg Laboratory, Max Planck Institute for Molecular Genetics (MPIMG), Berlin, Germany.

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http://dx.doi.org/10.1038/nmeth.2397DOI Listing
April 2013

Involvement of the MLL gene in adult T-lymphoblastic leukemia.

Genes Chromosomes Cancer 2012 Dec 25;51(12):1114-24. Epub 2012 Aug 25.

Labor Berlin, Abteilung Tumorzytogenetik, Berlin, Germany.

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http://dx.doi.org/10.1002/gcc.21996DOI Listing
December 2012

The power of NGS technologies to delineate the genome organization in cancer: from mutations to structural variations and epigenetic alterations.

Cancer Metastasis Rev 2011 Jun;30(2):199-210

Max Planck Institute for Molecular Genetics, Ihnestr. 63-73, 14195, Berlin, Germany.

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http://dx.doi.org/10.1007/s10555-011-9278-zDOI Listing
June 2011

Human inter-individual DNA sequence variation in candidate genes, drug targets, the importance of haplotypes and pharmacogenomics.

Curr Pharm Biotechnol 2003 Dec;4(6):351-78

Genetic Variation Program, Department of Vertebrate Genomics, Max Planck Institute for Molecular Genetics, Ihnestrasse 73, D-14195 Berlin, Germany.

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http://dx.doi.org/10.2174/1389201033377300DOI Listing
December 2003

Beta-2 adrenergic receptor gene variations and coping styles in twins.

Biol Psychol 2002 Oct;61(1-2):97-109

HealthTwiSt, Wiltberg Strasse 50, 13125 Berlin, Germany.

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October 2002