Bernardo L Trigatti

Bernardo L Trigatti

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Bernardo L Trigatti

Bernardo L Trigatti

Publications by authors named "Bernardo L Trigatti"

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Treatment with apolipoprotein A1 protects mice against doxorubicin-induced cardiotoxicity in a scavenger receptor class B type I dependent manner.

Am J Physiol Heart Circ Physiol 2019 Apr 19. Epub 2019 Apr 19.

Biochemistry and Biomedical Sciences; and Thrombosis and Atherosclerosis Research Institute, McMaster University, Canada.

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https://www.physiology.org/doi/10.1152/ajpheart.00432.2018
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http://dx.doi.org/10.1152/ajpheart.00432.2018DOI Listing
April 2019

PDZK1 in leukocytes protects against cellular apoptosis and necrotic core development in atherosclerotic plaques in high fat diet fed ldl receptor deficient mice.

Atherosclerosis 2018 Sep 16;276:171-181. Epub 2018 May 16.

Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, L8S 4L8, Canada; Thrombosis and Atherosclerosis Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, L8L 2X2, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.atherosclerosis.2018.05.009DOI Listing
September 2018

Data on leukocyte PDZK1 deficiency affecting macrophage apoptosis but not monocyte recruitment, cell proliferation, macrophage abundance or ER stress in atherosclerotic .

Data Brief 2018 Aug 26;19:1148-1161. Epub 2018 May 26.

Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada L8S 4L8.

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http://dx.doi.org/10.1016/j.dib.2018.05.128DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6141767PMC
August 2018

High-density lipoprotein protects cardiomyocytes against necrosis induced by oxygen and glucose deprivation through SR-B1, PI3K, and AKT1 and 2.

Biochem J 2018 04 5;475(7):1253-1265. Epub 2018 Apr 5.

Thrombosis and Atherosclerosis Research Institute, McMaster University and Hamilton Health Sciences, 237 Barton St. E. Hamilton, Ontario, Canada L8L 2X2

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http://dx.doi.org/10.1042/BCJ20170703DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5887020PMC
April 2018

HDL protects against doxorubicin-induced cardiotoxicity in a scavenger receptor class B type 1-, PI3K-, and Akt-dependent manner.

Am J Physiol Heart Circ Physiol 2018 01 6;314(1):H31-H44. Epub 2017 Oct 6.

Medical Sciences Graduate Program, McMaster University , Hamilton, Ontario , Canada.

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http://dx.doi.org/10.1152/ajpheart.00521.2016DOI Listing
January 2018

Rosuvastatin Reduces Aortic Sinus and Coronary Artery Atherosclerosis in SR-B1 (Scavenger Receptor Class B Type 1)/ApoE (Apolipoprotein E) Double Knockout Mice Independently of Plasma Cholesterol Lowering.

Arterioscler Thromb Vasc Biol 2018 01 21;38(1):26-39. Epub 2017 Nov 21.

From the Thrombosis and Atherosclerosis Research Institute, McMaster University and Hamilton Health Sciences (P.Y., T.X., C.B.T., R.N., M.E.M., P.L.G., R.C.A., B.L.T.), St. Joseph's Hamilton Healthcare and Hamilton Center for Kidney Research (P.L., R.C.A.), Department of Biochemistry and Biomedical Sciences (P.Y., T.X., C.B.T., M.E.M., B.L.T.), and Department of Medicine (P.L., R.N., P.L.G., R.C.A.), McMaster University, Hamilton, ON, Canada.

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https://www.ahajournals.org/doi/10.1161/ATVBAHA.117.305140
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http://dx.doi.org/10.1161/ATVBAHA.117.305140DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5757666PMC
January 2018

Sphingosine-1-Phosphate Receptor 1, Expressed in Myeloid Cells, Slows Diet-Induced Atherosclerosis and Protects against Macrophage Apoptosis in Ldlr KO Mice.

Int J Mol Sci 2017 Dec 15;18(12). Epub 2017 Dec 15.

Department of Biochemistry and Biomedical Sciences, and Thrombosis and Atherosclerosis Research Institute, McMaster University, Hamilton, ON L8L 2X2, Canada.

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http://dx.doi.org/10.3390/ijms18122721DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5751322PMC
December 2017

Suppression of NK and CD8 T cells reduces astrogliosis but accelerates cerebellar dysfunction and shortens life span in a mouse model of Sandhoff disease.

J Neuroimmunol 2017 05 6;306:55-67. Epub 2017 Mar 6.

Department of Biology, McMaster University, Hamilton, Ontario, Canada; Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01655728163043
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http://dx.doi.org/10.1016/j.jneuroim.2017.03.004DOI Listing
May 2017

SR-B1 and PDZK1: partners in HDL regulation.

Curr Opin Lipidol 2017 Apr;28(2):201-208

aDepartment of Biochemistry and Biomedical Sciences, McMaster University bThrombosis and Atherosclerosis Research Institute, Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.1097/MOL.0000000000000396DOI Listing
April 2017

Characterization of Proliferating Lesion-Resident Cells During All Stages of Atherosclerotic Growth.

J Am Heart Assoc 2016 08 15;5(8). Epub 2016 Aug 15.

Division of Nephrology, Department of Medicine, McMaster University, Hamilton, Ontario, Canada Hamilton Centre for Kidney Research, St. Joseph's Healthcare Hamilton, Hamilton, Ontario, Canada

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http://dx.doi.org/10.1161/JAHA.116.003945DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5015311PMC
August 2016

Rare Genetic Variants and High-Density Lipoprotein: Marching to a Different Drum.

Arterioscler Thromb Vasc Biol 2016 06 28;36(6):e53-5. Epub 2016 Apr 28.

From the Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada (B.L.T.); Thrombosis and Atherosclerosis Research Institute, McMaster University and Hamilton Health Sciences, Hamilton, Ontario, Canada (B.L.T.); and Department of Medicine and Robarts Research Institute, Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada (R.A.H.).

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http://dx.doi.org/10.1161/ATVBAHA.116.307688DOI Listing
June 2016

HDL signaling and protection against coronary artery atherosclerosis in mice.

J Biomed Res 2016 Mar 20;30(2):94-100. Epub 2015 Aug 20.

Department of Biochemistry and Biomedical Sciences, McMaster University and Thrombosis and Atherosclerosis Research Institute, McMaster University and Hamilton Health Sciences., Hamilton, Ontario L8L 2X2, Canada.

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http://dx.doi.org/10.7555/JBR.30.20150079DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4820886PMC
March 2016

Interleukin-15 modulates adipose tissue by altering mitochondrial mass and activity.

PLoS One 2014 17;9(12):e114799. Epub 2014 Dec 17.

Department of Pathology and Molecular Medicine and McMaster Immunology Research Centre, McMaster University, Hamilton, Ontario, Canada; Institute for Infectious Disease Research, McMaster University, Hamilton, Ontario, Canada.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0114799PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4269394PMC
September 2015

Characterization of mice harboring a variant of EPCR with impaired ability to bind protein C: novel role of EPCR in hematopoiesis.

Blood 2015 Jul 4;126(5):673-82. Epub 2015 Jun 4.

Thrombosis and Atherosclerosis Research Institute, Hamilton, ON, Canada; and Department of Medicine, McMaster University, Hamilton, ON, Canada.

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http://dx.doi.org/10.1182/blood-2014-02-558940DOI Listing
July 2015

High density lipoprotein stimulated migration of macrophages depends on the scavenger receptor class B, type I, PDZK1 and Akt1 and is blocked by sphingosine 1 phosphate receptor antagonists.

PLoS One 2014 4;9(9):e106487. Epub 2014 Sep 4.

Department of Biochemistry and Biomedical Sciences, and the Thrombosis and Atherosclerosis Research Institute, McMaster University, Hamilton, Ontario, Canada.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0106487PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4154704PMC
May 2015

The effects of diet on occlusive coronary artery atherosclerosis and myocardial infarction in scavenger receptor class B, type 1/low-density lipoprotein receptor double knockout mice.

Arterioscler Thromb Vasc Biol 2014 Nov 11;34(11):2394-403. Epub 2014 Sep 11.

From the Departments of Biochemistry and Biomedical Sciences (M.F., O.D., V.S., D.A., M.M., N.D., B.L.T.), Pathology and Molecular Medicine (J.M., S.A.I.), and Biology (S.A.I.), McMaster University, Hamilton, Ontario, Canada; and Thrombosis and Atherosclerosis Research Institute, Hamilton Health Sciences and McMaster University, Hamilton, Ontario, Canada (M.F., O.D., V.S., M.M., N.D., B.L.T.).

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http://dx.doi.org/10.1161/ATVBAHA.114.304200DOI Listing
November 2014

SR-BI in bone marrow derived cells protects mice from diet induced coronary artery atherosclerosis and myocardial infarction.

PLoS One 2013 13;8(8):e72492. Epub 2013 Aug 13.

Department of Biochemistry and Biomedical Sciences and Thrombosis and Atherosclerosis Research Institute, McMaster University, Hamilton, Ontario, Canada.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0072492PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3742605PMC
May 2014

The effect of pomegranate extract on coronary artery atherosclerosis in SR-BI/APOE double knockout mice.

Atherosclerosis 2013 May 7;228(1):80-9. Epub 2013 Mar 7.

Department of Biochemistry and Biomedical Sciences, McMaster University, 1280 Main St W, Hamilton, Ontario, Canada L8S 4L8.

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http://dx.doi.org/10.1016/j.atherosclerosis.2013.02.025DOI Listing
May 2013

Modifications in perfringolysin O domain 4 alter the cholesterol concentration threshold required for binding.

Biochemistry 2012 Apr 13;51(16):3373-82. Epub 2012 Apr 13.

Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON, Canada.

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http://dx.doi.org/10.1021/bi3003132DOI Listing
April 2012

Modulators of Protein Kinase C Affect SR-BI-Dependent HDL Lipid Uptake in Transfected HepG2 Cells.

Cholesterol 2011 5;2011:687939. Epub 2011 Jan 5.

Atherothrombosis Research Group, Department of Biochemistry and Biomedical Sciences, Thrombosis and Atherosclerosis Research Institute, Hamilton Health Sciences, McMaster University, 1200 Main St. W. Hamilton, ON, Canada L8N 3Z5.

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http://dx.doi.org/10.1155/2011/687939DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3065880PMC
July 2011

A role for the scavenger receptor, class B type I in high density lipoprotein dependent activation of cellular signaling pathways.

Biochim Biophys Acta 2010 Dec 21;1801(12):1239-48. Epub 2010 Aug 21.

Department of Biochemistry and Biomedical Sciences, Hamilton, Ontario, Canada.

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http://linkinghub.elsevier.com/retrieve/pii/S138819811000184
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http://dx.doi.org/10.1016/j.bbalip.2010.08.006DOI Listing
December 2010

Interleukin-15 contributes to the regulation of murine adipose tissue and human adipocytes.

Obesity (Silver Spring) 2010 Aug 17;18(8):1601-7. Epub 2009 Dec 17.

Department of Pathology and Molecular Medicine, Centre for Gene Therapeutics, McMaster University, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.1038/oby.2009.445DOI Listing
August 2010

Myocardial infarction following atherosclerosis in murine models.

Curr Drug Targets 2008 Mar;9(3):217-23

Biology Department, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA.

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March 2008

Liver X receptor stimulates cholesterol efflux and inhibits expression of proinflammatory mediators in human airway smooth muscle cells.

Mol Endocrinol 2007 Jun 3;21(6):1324-34. Epub 2007 Apr 3.

Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.1210/me.2007-0017DOI Listing
June 2007

Cholesterol depletion inhibits fatty acid uptake without affecting CD36 or caveolin-1 distribution in adipocytes.

Biochem Biophys Res Commun 2007 Mar 2;355(1):67-71. Epub 2007 Feb 2.

Department of Biochemistry and Biomedical Sciences, 1200 Main St. W. Hamilton, Ont., Canada L8N 3Z5.

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http://dx.doi.org/10.1016/j.bbrc.2007.01.135DOI Listing
March 2007

Regulation of SR-BI-mediated selective lipid uptake in Chinese hamster ovary-derived cells by protein kinase signaling pathways.

J Lipid Res 2007 Feb 1;48(2):405-16. Epub 2006 Nov 1.

Departments of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.1194/jlr.M600326-JLR200DOI Listing
February 2007

Hepatic high-density lipoprotein receptors: roles in lipoprotein metabolism and potential for therapeutic modulation.

Curr Atheroscler Rep 2005 Sep;7(5):344-50

Department of Biochemistry and Biomedical Sciences, Faculty of Health Sciences, McMaster University, West Hamilton, ON L8N 3Z5, Canada.

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September 2005

Biochemical demonstration of the involvement of fatty acyl-CoA synthetase in fatty acid translocation across the plasma membrane.

J Biol Chem 2004 Jun 2;279(23):24163-70. Epub 2004 Apr 2.

Department of Biochemistry, McMaster University, Hamilton, Ontario, L8N 3Z5, Canada.

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http://www.jbc.org/lookup/doi/10.1074/jbc.M313632200
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http://dx.doi.org/10.1074/jbc.M313632200DOI Listing
June 2004

Influence of the HDL receptor SR-BI on lipoprotein metabolism and atherosclerosis.

Arterioscler Thromb Vasc Biol 2003 Oct 14;23(10):1732-8. Epub 2003 Aug 14.

Department of Biochemistry, McMaster University, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.1161/01.ATV.0000091363.28501.84DOI Listing
October 2003

Scavenger receptor class B type I-mediated protection against atherosclerosis in LDL receptor-negative mice involves its expression in bone marrow-derived cells.

Arterioscler Thromb Vasc Biol 2003 Sep 26;23(9):1589-94. Epub 2003 Jun 26.

Department of Biochemistry, McMaster University, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.1161/01.ATV.0000083343.19940.A0DOI Listing
September 2003

Failure of red blood cell maturation in mice with defects in the high-density lipoprotein receptor SR-BI.

Blood 2002 Mar;99(5):1817-24

Division of Hematology/Oncology, Children's Hospital, Boston, MA 02115, USA.

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March 2002