Bernard Yan

Bernard Yan

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Determining the optimal dose of tenecteplase before endovascular therapy for ischemic stroke (EXTEND-IA TNK Part 2): A multicenter, randomized, controlled study.

Int J Stroke 2019 Sep 30:1747493019879652. Epub 2019 Sep 30.

Department of Medicine and Neurology, Melbourne Brain Centre at the Royal Melbourne Hospital, University of Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1177/1747493019879652DOI Listing
September 2019

Safety of Endovascular Thrombectomy for Acute Ischaemic Stroke in Anticoagulated Patients Ineligible for Intravenous Thrombolysis.

Cerebrovasc Dis 2018 1;46(5-6):193-199. Epub 2018 Nov 1.

Department of Radiology, Neurointervention Service, Royal Melbourne Hospital, University of Melbourne, Melbourne, Victoria, Australia,

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http://dx.doi.org/10.1159/000493801DOI Listing
July 2019

Endovascular Clot Retrieval by Hub-and-Spoke Service Delivery is Feasible Compared with Direct-to-Mothership.

Cerebrovasc Dis 2018 9;46(3-4):172-177. Epub 2018 Oct 9.

Department of Radiology, Neurointervention Service, Royal Melbourne Hospital, Melbourne, Victoria,

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https://www.karger.com/Article/FullText/490421
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http://dx.doi.org/10.1159/000490421DOI Listing
June 2019

Perfusion imaging INSPIREs precision medicine in stroke.

Neurology 2019 Jun 1;92(23):1075-1076. Epub 2019 May 1.

From the Institute of Neuroscience & Psychology (K.W.M.), University of Glasgow, Queen Elizabeth University Hospital, UK; and Neurointervention Service (B.Y.), Melbourne Brain Centre, Royal Melbourne Hospital, University of Melbourne, Parkville, Australia.

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http://dx.doi.org/10.1212/WNL.0000000000007554DOI Listing
June 2019

Thrombolysis Guided by Perfusion Imaging up to 9 Hours after Onset of Stroke.

N Engl J Med 2019 05;380(19):1795-1803

From Florey Institute of Neuroscience and Mental Health (H.M., L. Churilov, N.Y., V.T., L. Carey, A.M., G.A.D.), the Department of Medicine and Neurology, Melbourne Brain Centre at the Royal Melbourne Hospital (B.C.V.C., M.W.P., L. Churilov, S. Christensen, N.Y., G.S., A.B., B.Y., A.M., S.M.D., G.A.D.), and the Department of Radiology, Royal Melbourne Hospital (P.M.D., B.Y., P.J.M.), University of Melbourne, Parkville, the Department of Medicine, School of Clinical Science, Monash University, Clayton (H.M., T.G.P.), the Departments of Medicine and Neurology, Melbourne Medical School, University of Melbourne and Western Health, Sunshine Hospital, St. Albans (T.W.), the Department of Neurosciences, Eastern Health and Eastern Health Clinical School, Monash University, Box Hill (H.M.D., C.F.B.), the Department of Neurology, University Hospital Geelong, Deakin University, Geelong (B.C.), the Department of Neurology, Austin Hospital, Austin Health, Heidelberg (V.T.), and Occupational Therapy, School of Allied Health, College of Science, Health and Engineering, La Trobe University, Bundoora (L. Carey), VIC, the Department of Neurology, Priority Research Centre for Brain and Mental Health Research, John Hunter Hospital (C.R.L., F.M.), University of Newcastle (J.S.), Newcastle, the Department of Neurology, Westmead Hospital (N.M.), the Department of Neurology, Royal North Shore Hospital and Kolling Institute, University of Sydney (M.K.), and the Department of Neurology, St. Vincent's Hospital Sydney (R.M.), Sydney, and the Department of Neurology, Gosford Hospital, Gosford (J.S.), NSW, the Department of Neurology, Royal Adelaide Hospital (T.J.K., J.J.), the Department of Neurology, Lyell McEwin Hospital (D.F.), and the Department of Neurology, Queen Elizabeth Hospital (J.J.), Adelaide, SA, the Department of Medicine, Sunshine Coast University Hospital, Nambour (R.G.), the Department of Neurology, Royal Brisbane and Women's Hospital and the University of Queensland, Brisbane (A.A.W.), and the Department of Neurology, Gold Coast University Hospital, Southport (A.S.), and Australia and Griffith University, Gold Coast (A.S.), QLD - all in Australia; the Graduate Institute of Clinical Medical Science (C.H.) and the School of Medicine (C.-H.T.), China Medical University, and the Department of Neurology, China Medical University Hospital (C.-H.T.), Taichung, the Department of Neurology, Tri-Service General Hospital, National Defense Medical Center (J.-T.L.), the Department of Neurology, Shuang Ho Hospital (C.-J.H.), the Department of Neurology, En Chu Kong Hospital (Y.S.), the Stroke Center and Department of Neurology, National Taiwan University Hospital (J.-S.J.), and the Department of Neurology, Shin Kong Wu Ho-Su Memorial Hospital, Taipei Medical University College of Medicine (L.-M.L.), Taipei, the Stroke Center and Department of Neurology, Changhua Christian Hospital, Changhua (M.-C.S.), the Department of Neurology, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan (C.-H.C.), and the Department of Neurology, Kaohsiung Veterans General Hospital, Kaohsiung (C.-H.L.) - all in Taiwan; the Department of Neurology, Helsinki University Hospital, Helsinki (S. Curtze, A.M.); the Department of Neurology, Auckland City Hospital, University of Auckland, Auckland, New Zealand (P.A.B.); and the Stanford Stroke Center, Stanford University, Stanford, CA (S. Christensen).

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http://www.nejm.org/doi/10.1056/NEJMoa1813046
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http://dx.doi.org/10.1056/NEJMoa1813046DOI Listing
May 2019

Prehospital idarucizumab prior to intravenous thrombolysis in a mobile stroke unit.

Int J Stroke 2019 04 17;14(3):265-269. Epub 2018 Jul 17.

1 Department of Neurology, Melbourne Brain Center at the Royal Melbourne Hospital, Melbourne, Australia.

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http://dx.doi.org/10.1177/1747493018790081DOI Listing
April 2019

Endovascular clot retrieval in acute stroke with large ischaemic core is not always associated with poor outcomes.

Intern Med J 2019 04;49(4):490-494

Department of Radiology, The Royal Melbourne Hospital, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1111/imj.14116DOI Listing
April 2019

Acute severe hepatitis with alemtuzumab and rechallenge after a year.

J Clin Neurosci 2019 Feb 19;60:158-160. Epub 2018 Oct 19.

Department of Gastroenterology, Royal Melbourne Hospital, Parkville, Victoria, Australia.

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https://linkinghub.elsevier.com/retrieve/pii/S09675868183144
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http://dx.doi.org/10.1016/j.jocn.2018.10.055DOI Listing
February 2019

Advanced clinical education for stroke physicians in China: The ACTION and SCA models.

Int J Stroke 2019 02 11;14(2):215-219. Epub 2019 Jan 11.

2 Melbourne Brain Centre at the Royal Melbourne Hospital and University of Melbourne, VIC, Australia.

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http://dx.doi.org/10.1177/1747493018816515DOI Listing
February 2019

Novel features for capturing temporal variations of rhythmic limb movement to distinguish convulsive epileptic and psychogenic nonepileptic seizures.

Epilepsia 2019 Jan 9;60(1):165-174. Epub 2018 Dec 9.

Department of Electrical and Electronic Engineering, The University of Melbourne, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1111/epi.14619DOI Listing
January 2019

Clot Migration Is Associated With Intravenous Thrombolysis in the Setting of Acute Ischemic Stroke.

Stroke 2018 12;49(12):3060-3062

From the Melbourne Brain Centre (Y.R., B.Y.), The University of Melbourne, Australia.

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https://www.ahajournals.org/doi/10.1161/STROKEAHA.118.022751
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http://dx.doi.org/10.1161/STROKEAHA.118.022751DOI Listing
December 2018

Higher admission fasting plasma glucose levels are associated with a poorer short-term neurologic outcome in acute ischemic stroke patients with good collateral circulation.

Acta Diabetol 2018 Jul 12;55(7):703-714. Epub 2018 Apr 12.

Melbourne Brain Centre at the Royal Melbourne Hospital, University of Melbourne, Parkville, VIC, 3050, Australia.

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http://dx.doi.org/10.1007/s00592-018-1139-6DOI Listing
July 2018

Insights into variations in preferred selection criteria for acute stroke endovascular therapy.

J Neurointerv Surg 2018 Jun 26;10(6):542-549. Epub 2017 Sep 26.

Department of Medicine, Melbourne Brain Centre, Royal Melbourne Hospital, University of Melbourne, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1136/neurintsurg-2017-013247DOI Listing
June 2018

Selection criteria for endovascular therapy for acute ischaemic stroke: Are patients missing out?

J Med Imaging Radiat Oncol 2018 Jun 9;62(3):345-354. Epub 2018 Jan 9.

Neurointervention Service, Department of Radiology, Royal Melbourne Hospital, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1111/1754-9485.12700DOI Listing
June 2018

Tenecteplase versus Alteplase before Thrombectomy for Ischemic Stroke.

N Engl J Med 2018 04;378(17):1573-1582

From the Departments of Medicine and Neurology, Melbourne Brain Centre (B.C.V.C., N.Y., B.Y., T.Y.W., D.G.S., E.R., H.Z., P.S., G.S., M.W.P., S.M.D.), and the Department of Radiology (P.J.M., R.J.D., S.J.B., P.M.D.), Royal Melbourne Hospital, and the Florey Institute of Neuroscience and Mental Health (L.C., N.Y., V.T., H.A., H.M., C.F.B., G.A.D.), University of Melbourne, Parkville, VIC, the Departments of Neurology (T.J.K.) and Radiology (R.S.), Royal Adelaide Hospital, and the Department of Neurology, Lyell McEwin Hospital (D.F.), Adelaide, SA, the Department of Neurosciences, Eastern Health and Eastern Health Clinical School (H.M.D., C.F.B.), and the Departments of Neurology (H.M., T.G.P.) and Radiology (W. Chong, R.V.C., L.-A.S.), Monash Medical Centre, Monash University, Clayton, VIC, the Departments of Neurology (V.T., M.S.) and Radiology (M.B., H.A.), Austin Hospital, Austin Health, Heidelberg, VIC, School of Medicine, Faculty of Health, Deakin University, Melbourne, VIC (H.A.), and the Departments of Medicine and Neurology, Melbourne Medical School, University of Melbourne and Western Health, Sunshine Hospital, St. Albans, VIC (T.W.), the Departments of Neurology (D.G.S., H.B.) and Radiology (K.R., D.L.), Princess Alexandra Hospital, and the Departments of Neurology (A.A.W., C.M.) and Radiology (A.C., K. Mitchell, J.C., K. Mahady), Royal Brisbane and Women's Hospital and the University of Queensland, Brisbane, the Departments of Neurology (P.B.) and Radiology (H.R., L.V.), Gold Coast University Hospital, Southport, QLD, and the Department of Neurology, Priority Research Centre for Brain and Mental Health Research, John Hunter Hospital, University of Newcastle, Newcastle, NSW (T.A., F.M., C.R.L., C.G.-E., M.W.P.), the Department of Neurology, Royal North Shore Hospital and Kolling Institute, University of Sydney (M.K.), and the Department of Radiology, Royal North Shore Hospital (T.J.H., K.C.F., B.S.S.), St. Leonards, and the Department of Radiology, Westmead Hospital, Sydney (T.J.H., K.C.F., B.S.S.) - all in Australia; and the Departments of Neurology (T.Y.W., J.N.F.) and Radiology (W. Collecutt), Christchurch Hospital, Christchurch, New Zealand.

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http://dx.doi.org/10.1056/NEJMoa1716405DOI Listing
April 2018

An Objective Measurement of Lacunar Infarct Location from the Middle Cerebral Artery Stem.

J Stroke Cerebrovasc Dis 2018 Mar 24;27(3):599-605. Epub 2017 Nov 24.

Melbourne Brain Centre, Royal Melbourne Hospital, University of Melbourne, Victoria, Melbourne, Australia; Department of Medicine (RMH), University of Melbourne, Melbourne, Victoria, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2017.09.040DOI Listing
March 2018

Association between implementation of a code stroke system and poststroke epilepsy.

Neurology 2018 03 21;90(13):e1126-e1133. Epub 2018 Feb 21.

From the Department of Neurology, Melbourne Brain Centre, Royal Melbourne Hospital (Ziyi Chen, Ziyuan Chen, J.N., M.K., B.Y., P.K.), and Florey Institute of Neuroscience and Mental Health, Austin Health (L.C.), The University of Melbourne, Australia; and Department of Neurology (Ziyi Chen), The First Affiliated Hospital, Sun Yat-Sen University, Guangzhou, China.

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http://www.neurology.org/lookup/doi/10.1212/WNL.000000000000
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http://dx.doi.org/10.1212/WNL.0000000000005212DOI Listing
March 2018

Trends in stroke subtypes and vascular risk factors in a stroke center in China over 10 years.

Sci Rep 2018 03 22;8(1):5037. Epub 2018 Mar 22.

Department of Neurology, Peking University Third Hospital, Beijing, China.

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http://dx.doi.org/10.1038/s41598-018-23356-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5864718PMC
March 2018

Association between hemorrhagic transformation after endovascular therapy and poststroke seizures.

Epilepsia 2018 02 30;59(2):403-409. Epub 2017 Dec 30.

Melbourne Brain Centre, Royal Melbourne Hospital, Parkville, Vic., Australia.

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http://doi.wiley.com/10.1111/epi.13982
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http://dx.doi.org/10.1111/epi.13982DOI Listing
February 2018

Post-Stroke Seizures Is Associated with Low Alberta Stroke Program Early CT Score.

Cerebrovasc Dis 2017 4;43(5-6):259-265. Epub 2017 Mar 4.

Melbourne Brain Centre, The Royal Melbourne Hospital, Department of Medicine, Parkville, VIC, Australia.

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http://dx.doi.org/10.1159/000458449DOI Listing
January 2018

Reliability and Utility of the Alberta Stroke Program Early Computed Tomography Score in Hyperacute Stroke.

J Stroke Cerebrovasc Dis 2017 Nov 23;26(11):2547-2552. Epub 2017 Jun 23.

Melbourne Brain Centre, Royal Melbourne Hospital, Parkville, Victoria, Australia; Department of Medicine, University of Melbourne, Parkville, Victoria, Australia.

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http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2017.05.042DOI Listing
November 2017

Smartphone electrographic monitoring for atrial fibrillation in acute ischemic stroke and transient ischemic attack.

Int J Stroke 2017 10 8;12(7):786-789. Epub 2017 Mar 8.

1 Melbourne Brain Centre, Royal Melbourne Hospital, the University of Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1177/1747493017696097DOI Listing
October 2017

Streamlining Workflow for Endovascular Mechanical Thrombectomy: Lessons Learned from a Comprehensive Stroke Center.

J Stroke Cerebrovasc Dis 2017 Aug 1;26(8):1655-1662. Epub 2017 Jun 1.

Melbourne Brain Centre, The Royal Melbourne Hospital, Parkville, Victoria, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2017.04.021DOI Listing
August 2017

1.4 times increase in atrial fibrillation-related ischemic stroke and TIA over 12years in a stroke center.

J Neurol Sci 2017 Aug 11;379:1-6. Epub 2017 May 11.

Department of Medicine and Neurology, Melbourne Brain Centre at the Royal Melbourne Hospital, University of Melbourne, Parkville, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.jns.2017.05.022DOI Listing
August 2017

Association between PTGS1 polymorphisms and functional outcomes in Chinese patients with stroke during aspirin therapy: Interaction with smoking.

J Neurol Sci 2017 May 14;376:211-215. Epub 2017 Mar 14.

Department of Neurology, Jinling Hospital, Southern Medical University, Nanjing 210002, Jiangsu, China. Electronic address:

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http://dx.doi.org/10.1016/j.jns.2017.03.014DOI Listing
May 2017

Blood Pressure May Be Associated with Arterial Collateralization in Anterior Circulation Ischemic Stroke before Acute Reperfusion Therapy.

J Stroke 2017 May 2;19(2):222-228. Epub 2017 May 2.

Department of Medicine and Neurology, Melbourne Brain Centre at the Royal Melbourne Hospital, University of Melbourne, Parkville, Australia.

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http://dx.doi.org/10.5853/jos.2016.01739DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5466288PMC
May 2017

The Basilar Artery on Computed Tomography Angiography Prognostic Score for Basilar Artery Occlusion.

Stroke 2017 03 22;48(3):631-637. Epub 2017 Feb 22.

From the Department of Medicine and Neurology, Royal Melbourne Hospital, University of Melbourne, Parkville, Australia (F.A., D.G.S., B.Y., S.M.D., B.C.V.C.); Department of Neurology (F.A., M.D., F.S., C.C.) and Department of Diagnostic Imaging and Interventional Radiology (R.F.), University Hospital Tor Vergata, Rome, Italy; I.R.C.C.S., Santa Lucia Foundation, Rome, Italy (M.D., C.C.); Department of Neurology, John Hunter Hospital, University of Newcastle, Australia (A.B., M.W.P., C.R.L.); and Department of Radiology, Royal Melbourne Hospital, University of Melbourne, Parkville, Australia (G.S., P.J.M., R.J.D., S.B.).

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http://dx.doi.org/10.1161/STROKEAHA.116.015492DOI Listing
March 2017

Simultaneous Multiple Intracerebral Hemorrhages (SMICH).

Stroke 2017 03;48(3):581-586

From the Department of Medicine and Neurology, Melbourne Brain Centre (T.Y.W., N.Y., D.G.S., M.M., B.C.V.C., B.Y., S.M.D., A.M.) and Department of Radiology (G.S., P.M.D.), the Royal Melbourne Hospital, University of Melbourne, Australia; Department of Neurology, Helsinki University Hospital, Finland (J.P., D.S., T.T., A.M.); Department of Neurology, Jinling Hospital, Nanjing University School of Medicine, People's Republic of China (M.M.); Institute of Neuroscience and Physiology, Sahlgrenska Academy at the University of Gothenburg, Sweden (T.T.); and Department of Neurology, Sahlgrenska University Hospital, Gothenburg, Sweden (T.T.).

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http://stroke.ahajournals.org/content/early/2017/02/23/STROK
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http://stroke.ahajournals.org/lookup/doi/10.1161/STROKEAHA.1
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http://dx.doi.org/10.1161/STROKEAHA.116.015186DOI Listing
March 2017

Plasmin (Human) Administration in Acute Middle Cerebral Artery Ischemic Stroke: Phase 1/2a, Open-Label, Dose-Escalation, Safety Study.

J Stroke Cerebrovasc Dis 2017 Feb 25;26(2):308-320. Epub 2016 Oct 25.

Comprehensive Stroke Center, Department of Neurology, UCLA Stroke Center, Los Angeles, California.

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http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2016.09.022DOI Listing
February 2017

Arterial Obstruction on Computed Tomographic or Magnetic Resonance Angiography and Response to Intravenous Thrombolytics in Ischemic Stroke.

Stroke 2017 02 22;48(2):353-360. Epub 2016 Dec 22.

From the Division of Neuroimaging Sciences (G.M., A.J.F., R.J.S., E.S., J.P., J.M.W.) and Division of Clinical Neurosciences (D.P., P.A.G.S.), University of Edinburgh, United Kingdom; Department of Neuroradiology, Dresden University Stroke Centre, Germany (R.v.K.); Stroke Center, Sacro Cuore-Don Calabria Hospital, Verona, Italy (A.A.); Stroke Research Group, Newcastle upon Tyne, United Kingdom (P.M.W.); National Hospital for Neurology and Neurosurgery, London, United Kingdom (M.E.A.); Neurovascular Research Group, Royal Melbourne Hospital, Australia (B.Y.); Calgary Stroke Program, Hotchkiss Brain Institute, University of Calgary, Canada (A.M.D.); and Westmead Hospital Clinical School and The George Institute for Global Health, University of Sydney, Australia (R.I.L.).

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http://dx.doi.org/10.1161/STROKEAHA.116.015164DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5266422PMC
February 2017

Platelet glycoprotein gene Ia C807T, HPA-3, and Ibα VNTR polymorphisms are associated with increased ischemic stroke risk: Evidence from a comprehensive meta-analysis.

Int J Stroke 2017 01 22;12(1):46-70. Epub 2016 Oct 22.

7 Melbourne Brain Centre, Royal Melbourne Hospital, University of Melbourne, Parkville, Victoria, Australia.

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http://dx.doi.org/10.1177/1747493016672085DOI Listing
January 2017

Large-Vessel Occlusion Is Associated with Poor Outcome in Stroke Patients Aged 80 Years or Older Who Underwent Intravenous Thrombolysis.

J Stroke Cerebrovasc Dis 2016 Nov 10;25(11):2712-2716. Epub 2016 Aug 10.

Department of Medicine and Neurology, Melbourne Brain Centre at the Royal Melbourne Hospital, University of Melbourne, Parkville, Victoria, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2016.07.021DOI Listing
November 2016

White Matter Hyperintensities on Brain Magnetic Resonance Imaging in People with Epilepsy: A Hospital-Based Study.

CNS Neurosci Ther 2016 09 6;22(9):758-63. Epub 2016 Jun 6.

Melbourne Brain Centre, Royal Melbourne Hospital, The University of Melbourne, Melbourne, Vic, Australia.

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http://dx.doi.org/10.1111/cns.12571DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6492825PMC
September 2016

Early Recanalization Postintravenous Thrombolysis in Ischemic Stroke with Large Vessel Occlusion: A Digital Subtraction Angiography Study.

CNS Neurosci Ther 2016 08 11;22(8):643-7. Epub 2016 May 11.

Department of Neurology, Royal Melbourne Hospital, The University of Melbourne, Melbourne, Vic., Australia.

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http://dx.doi.org/10.1111/cns.12549DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6492813PMC
August 2016

Diagnosing acute lacunar infarction using CT perfusion.

J Clin Neurosci 2016 Jul 15;29:70-2. Epub 2016 Feb 15.

Department of Medicine and Neurology, Melbourne Brain Centre at the Royal Melbourne Hospital, University of Melbourne, Grattan Street, Parkville, VIC 3050, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.jocn.2016.01.001DOI Listing
July 2016

Computed tomography perfusion as a diagnostic tool for seizures after ischemic stroke.

Neuroradiology 2016 Jun 9;58(6):577-584. Epub 2016 Mar 9.

Melbourne Brain Centre, The Royal Melbourne Hospital, Parkville, VIC, 3050, Australia.

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http://dx.doi.org/10.1007/s00234-016-1670-5DOI Listing
June 2016

"MOONSTROKE": Lunar patterns of stroke occurrence combined with circadian and seasonal rhythmicity--A hospital based study.

Chronobiol Int 2015 ;32(7):881-8

a Melbourne Brain Centre, Royal Melbourne Hospital, University of Melbourne , Parkville , Australia .

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http://dx.doi.org/10.3109/07420528.2015.1049614DOI Listing
May 2016

PRKCH 1425G/A Polymorphism Predicts Recurrence of Ischemic Stroke in a Chinese Population.

Mol Neurobiol 2015 Dec 5;52(3):1648-1653. Epub 2014 Nov 5.

Department of Neurology, Jinling Hospital, Nanjing University School of Medicine, 305# East Zhongshan Road, Nanjing, 210002, Jiangsu Province, China.

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http://dx.doi.org/10.1007/s12035-014-8964-6DOI Listing
December 2015

Endovascular Therapy Is Effective and Safe for Patients With Severe Ischemic Stroke: Pooled Analysis of Interventional Management of Stroke III and Multicenter Randomized Clinical Trial of Endovascular Therapy for Acute Ischemic Stroke in the Netherlands Data.

Stroke 2015 Dec 20;46(12):3416-22. Epub 2015 Oct 20.

From the Departments of Neurology and Rehabilitation Medicine and Radiology, University of Cincinnati Neuroscience Institute, University of Cincinnati Academic Health Center, Cincinnati, OH (J.P.B., P.K., J.S., J.C., T.A.T.); Division of Emergency Medicine (E.C.J.), Department of Public Health Sciences (Y.Y.P., L.D.F.), and Department of Healthcare Management and Leadership (K.N.S.), Medical University of South Carolina, Charleston; Calgary Stroke Program, Seaman Family MR Research Centre, Departments of Clinical Neurosciences and Radiology, Hotchkiss Brain Institute, University of Calgary, Calgary, Alberta, Canada (A.M.D., M.D.H., M.G., K.J.R.); the Stroke Institute, University of Pittsburgh Medical Center, PA (T.G.J.); Melbourne Brain Centre, Royal Melbourne Hospital, University of Melbourne, Melbourne, Victoria, Australia (B.Y.); Department of Neuroradiology, Dresden University Stroke Center, University Hospital, Dresden, Germany (R.v.K.); Neurovascular Unit, Department of Neurology, Hospital Universitari Vall d'Hebron, Barcelona, Spain (C.A.M.); Department of Neurology, University Medical Center Utrecht and the Rudolph Magnus Institute of Neurosciences, Utrecht, the Netherlands (W.J.S.); St. Antonius Hospital, Nieuwegein, the Netherlands (W.J.S.); Department of Neurology and Stroke Center, Lariboisière Hospital, Paris, France (M.M.); Department of Neurology, Basel University Hospital, Basel, Switzerland (S.T.E.); the George Institute for Global Health, Royal Prince Alfred Hospital, University of Sydney, Sydney (C.S.A.); and the National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD (L.S.J.); the Department of Radiology (O.A.B., C.B.L.M.M.) and Neurology (Y.B.W.E.M.R.), Academic Medical Center, Amsterdam, the Netherlands; Department of Neurology (D.W.J.D., B.R.), Radiology (A.v.d.L.), and Public Health (H.F.L.), Erasmus MC University Medical Center, Rotterdam, Netherlands; and Department of Radiology (W.H.v.Z.) and N

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http://dx.doi.org/10.1161/STROKEAHA.115.011397DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4659737PMC
December 2015

Does large vessel occlusion affect clinical outcome in stroke with mild neurologic deficits after intravenous thrombolysis?

J Stroke Cerebrovasc Dis 2014 Nov-Dec;23(10):2888-93. Epub 2014 Oct 16.

Department of Medicine and Neurology, Melbourne Brain Centre at the Royal Melbourne Hospital, University of Melbourne, Parkville, Victoria, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2014.07.018DOI Listing
November 2015

Every 15-min delay in recanalization by intra-arterial therapy in acute ischemic stroke increases risk of poor outcome.

Int J Stroke 2015 Oct 28;10(7):1062-7. Epub 2015 Apr 28.

Melbourne Brain Centre, Royal Melbourne Hospital, Melbourne, Vic., Australia.

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http://dx.doi.org/10.1111/ijs.12495DOI Listing
October 2015

REVASCAT Trial: Further Advancement in Endovascular Stroke Therapy.

Stroke 2015 Oct 3;46(10):3012-3. Epub 2015 Sep 3.

From the Department of Neurology, University of California San Francisco (W.S.S.); and Melbourne Brain Center, Royal Melbourne Hospital, University of Melbourne, Melbourne, VIC, Australia (B.Y.).

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October 2015

Successful recanalization post endovascular therapy is associated with a decreased risk of intracranial haemorrhage: a retrospective study.

BMC Neurol 2015 Oct 7;15:185. Epub 2015 Oct 7.

Melbourne Brain Centre, Royal Melbourne Hospital, University of Melbourne, 300 Grattan St, Parkville, Victoria, 3050, Australia.

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http://dx.doi.org/10.1186/s12883-015-0442-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4597389PMC
October 2015

Mechanical Thrombectomy Is Now the Gold Standard for Acute Ischemic Stroke: Implications for Routine Clinical Practice.

Interv Neurol 2015 Oct 18;4(1-2):18-29. Epub 2015 Sep 18.

Melbourne Brain Centre, Royal Melbourne Hospital, University of Melbourne, Parkville, Vic., Australia.

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http://dx.doi.org/10.1159/000438774DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640090PMC
October 2015

Endovascular Therapy Proven for Stroke – Finally!

Heart Lung Circ 2015 Aug 21;24(8):733-5. Epub 2015 Apr 21.

Department of Medicine and Neurology, Melbourne Brain Centre at the Royal Melbourne Hospital, University of Melbourne, Melbourne, Australia.

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http://dx.doi.org/10.1016/j.hlc.2015.04.001DOI Listing
August 2015

Impact of General Anesthesia on Safety and Outcomes in the Endovascular Arm of Interventional Management of Stroke (IMS) III Trial.

Stroke 2015 Aug 2;46(8):2142-8. Epub 2015 Jul 2.

From Baptist Neuroscience Associates, Baptist Health, Louisville, KY (A.A.-C.); Department of Public Health Sciences, Medical University of South Carolina, Charleston (S.D.Y.); Department of Neurology, Royal Melbourne Hospital, Parkville, Australia (B.Y.); Departments of Neurosurgery, Radiology, and Public Health Sciences, Penn State Hershey, PA (K.C.); Departments of Radiology and Clinical Neurosciences, Foothills Medical Centre, Calgary, AB, Canada (M.G.); Department of Neurology, University of Pittsburgh Medical Center, PA (T.J.); Department of Neurology (P.K., J.S., J.B.) and Department of Radiology (T.T.), University of Cincinnati, OH; Departments of Radiology and Neurological Surgery, Columbia University, New York, NY (P.M.); Department of Neurology, University of Mississippi, Jackson (R.S.); Department of Neurology, Martin-Luther-University Halle-Wittenberg, Halle, Germany (K.E.W.); and Department of Clinical Neurosciences and Hotchkiss Brain Institute, University of Calgary, Calgary, AB, Canada (M.D.H.).

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http://dx.doi.org/10.1161/STROKEAHA.115.008761DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4519363PMC
August 2015

Low Alberta Stroke Program Early CT score (ASPECTS) associated with malignant middle cerebral artery infarction.

Cerebrovasc Dis 2014 16;38(1):39-45. Epub 2014 Sep 16.

Melbourne Brain Centre at Royal Melbourne Hospital, Melbourne, Australia.

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http://dx.doi.org/10.1159/000363619DOI Listing
July 2015

Reply to the letter from Dale Ding, MD.

Cerebrovasc Dis 2014 25;38(5):393-4. Epub 2014 Nov 25.

Melbourne Brain Centre at Royal Melbourne Hospital, The University of Melbourne, Melbourne, Australia.

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http://dx.doi.org/10.1159/000369118DOI Listing
July 2015

Hypertrophic olivary degeneration secondary to pontine haemorrhage.

J Clin Neurosci 2015 Jul 8;22(7):1213-4. Epub 2015 Apr 8.

Department of Radiology, First Floor, 1B Building, The Royal Melbourne Hospital, Grattan Street, Parkville, VIC 3050, Australia; Department of Radiology, The University of Melbourne, Parkville, VIC, Australia.

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http://dx.doi.org/10.1016/j.jocn.2015.02.005DOI Listing
July 2015

Safeguarding the safety of stroke patients: credentialing of neurointerventionists for mechanical thrombectomy.

Int J Stroke 2015 Jul;10(5):653-4

Neurointervention Service, Royal Melbourne Hospital, Parkville, Melbourne, Australia.

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http://dx.doi.org/10.1111/ijs.12540DOI Listing
July 2015

Is there association between hyperdense middle cerebral artery sign on CT scan and time from stroke onset within the first 24-hours?

BMC Neurol 2015 Jul 3;15:101. Epub 2015 Jul 3.

Department of Radiology, Neurointervention Service, Royal Melbourne Hospital, Parkville, Victoria, 3050, Australia.

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http://bmcneurol.biomedcentral.com/articles/10.1186/s12883-0
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http://dx.doi.org/10.1186/s12883-015-0358-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4489032PMC
July 2015

Wireless accelerometry is feasible in acute monitoring of upper limb motor recovery after ischemic stroke.

Cerebrovasc Dis 2014 5;37(5):336-41. Epub 2014 Jun 5.

Melbourne Brain Centre, University of Melbourne and Melbourne Health, Parkville, Vic., Australia.

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May 2015

Twelve-Month Clinical and Quality-of-Life Outcomes in the Interventional Management of Stroke III Trial.

Stroke 2015 May 9;46(5):1321-7. Epub 2015 Apr 9.

From the Departments of Neurology and Rehabilitation Medicine and Radiology, University of Cincinnati Neuroscience Institute, University of Cincinnati Academic Health Center, Cincinnati (J.P.B., P.K., J.S., J.C., T.A.T.); Department of Public Health Sciences (Y.Y.P., S.D.Y., L.D.F., A.S., K.N.S.) and Division of Emergency Medicine (E.C.J.), Medical University of South Carolina, Charleston; Calgary Stroke Program, Seaman Family MR Research Centre, Departments of Clinical Neurosciences and Radiology, Hotchkiss Brain Institute, University of Calgary, Calgary, AB, Canada (A.M.D., M.D.H., M.G., K.J.R.); Stroke Institute, University of Pittsburgh Medical Center, Pittsburgh (T.G.J.); Melbourne Brain Centre, Royal Melbourne Hospital, University of Melbourne, Melbourne, VIC, Australia (B.Y.); Department of Neuroradiology, Dresden University Stroke Center, University Hospital, Dresden, Germany (R.v.K.); Neurovascular Unit, Department of Neurology, Hospital Universitari Vall d'Hebron, Barcelona (C.A.M.); Department of Neurology, University Medical Center Utrecht and the Rudolph Magnus Institute of Neurosciences, Utrecht, the Netherlands, and the St. Antonius Hospital, Nieuwegein, the Netherlands (W.J.S.); Department of Neurology and Stroke Center, Lariboisière Hospital, Paris (M.M.); Department of Neurology, Basel University Hospital, Basel, Switzerland (S.T.E.); George Institute for Global Health, Royal Prince Alfred Hospital, University of Sydney, Sydney (C.A.); and National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD (L.S.J.).

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http://dx.doi.org/10.1161/STROKEAHA.115.009180DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4414900PMC
May 2015

Evolution of Endovascular Therapy in Acute Stroke: Implications of Device Development.

J Stroke 2015 May 29;17(2):127-37. Epub 2015 May 29.

Comprehensive Stroke Centre, Royal Melbourne Hospital, Parkville, Victoria, Australia.

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http://dx.doi.org/10.5853/jos.2015.17.2.127DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4460332PMC
May 2015

Thrombus composition in acute ischemic stroke: a histopathological study of thrombus extracted by endovascular retrieval.

J Neuroradiol 2015 Apr 20;42(2):86-92. Epub 2014 Feb 20.

Melbourne Brain Centre, Level 4, Royal Melbourne Hospital, Parkville, Victoria 3050, Australia; Neurointervention Service, Department of Radiology, Royal Melbourne Hospital, Parkville, Victoria 3050, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.neurad.2014.01.124DOI Listing
April 2015

Intracranial aneurysms with perianeurysmal edema: long-term outcomes post-endovascular treatment.

J Neuroradiol 2015 Apr 23;42(2):72-9. Epub 2014 Jun 23.

Department of Radiology, Neurointervention Service, The Royal Melbourne Hospital, Melbourne, Victoria, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.neurad.2014.05.001DOI Listing
April 2015

Remote intracerebral haemorrhage post intravenous thrombolysis: experience from an Australian stroke centre.

J Clin Neurosci 2015 Feb 7;22(2):352-6. Epub 2014 Oct 7.

Melbourne Brain Centre, Royal Melbourne Hospital, University of Melbourne, Grattan Street, Parkville, VIC 3050, Australia; Department of Medicine, University of Melbourne, Parkville, VIC, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.jocn.2014.07.009DOI Listing
February 2015

Proximal hyperdense middle cerebral artery sign predicts poor response to thrombolysis.

PLoS One 2014 7;9(5):e96123. Epub 2014 May 7.

Department of Neurology, Royal Melbourne Hospital, The University of Melbourne, Melbourne, Australia.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4013049PMC
January 2015

Presence of anterior temporal artery associates with good outcome in acute atherosclerotic M1-middle cerebral artery occlusion.

Neuroradiology 2014 Dec 9;56(12):1023-30. Epub 2014 Sep 9.

Department of Neurology, Jinling Hospital, Nanjing University School of Medicine, 305 East Zhongshan Road, Nanjing, 210002, Jiangsu Province, PR China.

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http://dx.doi.org/10.1007/s00234-014-1422-3DOI Listing
December 2014

Evolution of practice during the Interventional Management of Stroke III Trial and implications for ongoing trials.

Stroke 2014 Dec 16;45(12):3606-11. Epub 2014 Oct 16.

From the Departments of Neurology and Rehabilitation Medicine and Radiology, University of Cincinnati Neuroscience Institute, University of Cincinnati Academic Health Center, Cincinnati (J.P.B., P.K., J.S., J.C., T.A.T.); Department of Public Health Sciences (Y.Y.P, S.D.Y., L.D.F.) and the Division of Emergency Medicine (E.C.J.), Medical University of South Carolina, Charleston; Calgary Stroke Program, Seaman Family MR Research Centre, Departments of Clinical Neurosciences and Radiology, Hotchkiss Brain Institute, University of Calgary, Calgary, AB, Canada (A.M.D., M.D.H., M.G.); Stroke Institute, University of Pittsburgh Medical Center, Pittsburgh (T.G.J.); Melbourne Brain Centre, Royal Melbourne Hospital, University of Melbourne, Melbourne, VIC, Australia (B.Y.); Department of Neuroradiology, Dresden University Stroke Center, University Hospital, Dresden, Germany (R.v.K.); Neurovascular Unit, Department of Neurology, Hospital Universitari Vall d'Hebron, Barcelona (C.A.M.); Department of Neurology, University Medical Center Utrecht and the Rudolph Magnus Institute of Neurosciences, Utrecht, the Netherlands, and the St. Antonius Hospital, Nieuwegein, the Netherlands (W.J.S.); Department of Neurology and Stroke Center, Lariboisière Hospital, Paris (M.M.); Department of Neurology, Basel University Hospital, Basel, Switzerland (S.T.E.); George Institute for Global Health, Royal Prince Alfred Hospital, University of Sydney, Sydney (C.A.); and National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD (L.S.J.).

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http://dx.doi.org/10.1161/STROKEAHA.114.005952DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4679363PMC
December 2014

Does warfarin-related intracerebral haemorrhage lead to higher costs of management?

Clin Neurol Neurosurg 2014 Nov 29;126:38-42. Epub 2014 Aug 29.

Melbourne Brain Centre, Royal Melbourne Hospital, University of Melbourne, Melbourne, Australia; Department of Medicine, University of Melbourne, Melbourne, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.clineuro.2014.08.022DOI Listing
November 2014

Machine learning for outcome prediction of acute ischemic stroke post intra-arterial therapy.

PLoS One 2014 10;9(2):e88225. Epub 2014 Feb 10.

Melbourne Brain Centre, Department of Medicine, Royal Melbourne Hospital, University of Melbourne, Parkville, Victoria, Australia.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0088225PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3919736PMC
October 2014

Recanalization and clinical outcome of occlusion sites at baseline CT angiography in the Interventional Management of Stroke III trial.

Radiology 2014 Oct 5;273(1):202-10. Epub 2014 Jun 5.

From the Calgary Stroke Program, Dept of Clinical Neurosciences and Radiology, Hotchkiss Brain Inst, Univ of Calgary, 1403 29 St NW, Room 112, Calgary, AB, Canada T2N 2T9 (A.M.D., M.G., E.Q., M.D.H.); Dept of Public Health Sciences, Medical Univ of South Carolina, Charleston, SC (S.D.Y., L.D.F., Y.Y.P.); Depts of Neurology and Rehabilitation Medicine and Radiology, Univ of Cincinnati Academic Health Ctr, Cincinnati, Ohio (J.C., P.K., T.A.T., J.P.B.); Stroke Inst, Univ of Pittsburgh Medical Ctr, Pittsburgh, Pa (T.G.J.); Neurovascular Unit, Dept of Neurology, Hosp Universitari Vall d'Hebron, Universitat Autonoma de Barcelona, Barcelona, Spain (M.R.); Melbourne Brain Ctr, The Royal Melbourne Hosp, Univ of Melbourne, Australia (B.Y.); Dept of Radiology, Medical College of Wisconsin, Milwaukee, Wis (O.O.Z.); Colorado Neurologic Inst, Denver, Colo (D.F.); Dept of Neuroradiology, Dresden Univ Stroke Ctr, Univ Hosp, Dresden, Germany (R.v.K.); Dept of Neurosurgery, Radiology and Public Health Sciences, Penn State M.S. Hershey Medical Ctr, Hershey, Pa (K.C.); and UCLA Stroke Ctr, Los Angeles, Calif (D.S.L.).

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http://pubs.rsna.org/doi/10.1148/radiol.14132649
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http://dx.doi.org/10.1148/radiol.14132649DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4174723PMC
October 2014

Leukoaraiosis and early neurological recovery after intravenous thrombolysis.

J Stroke Cerebrovasc Dis 2014 Oct 27;23(9):2431-6. Epub 2014 Aug 27.

Melbourne Brain Centre, Royal Melbourne Hospital, Melbourne, Australia; Neurointervention Service, Department of Radiology, Royal Melbourne Hospital, Melbourne, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2014.05.012DOI Listing
October 2014

Recanalisation success is independent of ASPECTS in predicting outcomes after intra-arterial therapy for acute ischaemic stroke.

J Clin Neurosci 2014 Aug 6;21(8):1344-8. Epub 2014 Feb 6.

Melbourne Brain Centre, Royal Melbourne Hospital, Parkville, VIC, Australia; Neurointervention Service, Department of Radiology, Royal Melbourne Hospital, Grattan Street, Parkville, VIC 3050, Australia. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09675868140004
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http://dx.doi.org/10.1016/j.jocn.2013.11.020DOI Listing
August 2014

Successful treatment of growing basilar artery dissecting aneurysm by pipeline flow diversion embolization device.

J Stroke Cerebrovasc Dis 2014 Jul 3;23(6):1713-6. Epub 2014 Jan 3.

Department of Radiology, Royal Melbourne Hospital, Parkville, Victoria, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2013.11.019DOI Listing
July 2014

Future directions for intra-arterial therapy for acute ischaemic stroke: is there life after three negative randomized controlled studies?

Interv Neurol 2014 May;2(3):97-104

Melbourne Brain Centre, Department of Radiology, Royal Melbourne Hospital, Melbourne, Vic., Australia ; Neurointervention Service, Department of Radiology, Royal Melbourne Hospital, Melbourne, Vic., Australia.

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http://dx.doi.org/10.1159/000356087DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4062314PMC
May 2014

Collaterals at angiography and outcomes in the Interventional Management of Stroke (IMS) III trial.

Stroke 2014 Mar 28;45(3):759-64. Epub 2014 Jan 28.

From UCLA Stroke Center, Los Angeles, CA (D.S.L.); University of Cincinnati, Cincinnati, OH (T.A.T., J.C., P.K., J.P.B.); Medical University of South Carolina, Charleston, SC (L.D.F., S.D.Y., Y.Y.P.); Departments of Clinical Neurosciences and Radiology, Hotchkiss Brain Institute, University of Calgary, Calgary, Alberta, Canada (A.M.D., M.G., B.K.M.); UPMC Stroke Institute, Pittsburgh, PA (T.G.J.); Department of Neuroradiology, University of Dresden, Dresden, Germany (R.v.K.); University of Mississippi, Jackson, MS (R.M.S.); Medical College of Wisconsin/Froedtert Hospital, Milwaukee, WI (O.O.Z.); Michigan State University, East Lansing, MI (S.I.H.); Summit Neurovascular Specialties and Akron General Hospital, Akron, OH (F.A.A.); and Royal Melbourne Hospital, Parkville, Victoria, Australia (B.Y.).

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http://dx.doi.org/10.1161/STROKEAHA.113.004072DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3977615PMC
March 2014

Warfarin therapy and predilection for infratentorial hemorrhage.

J Neurol Sci 2014 Feb 16;337(1-2):239. Epub 2013 Nov 16.

Melbourne Brain Centre, Royal Melbourne Hospital, Melbourne, Australia; Department of Medicine, University of Melbourne, Melbourne, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.jns.2013.11.010DOI Listing
February 2014

Efficacy, complications and clinical outcome of endovascular treatment for intracranial intradural arterial dissections.

Clin Neurol Neurosurg 2014 Feb 1;117:6-11. Epub 2013 Dec 1.

Department of Neurology, The Royal Melbourne Hospital, Parkville, Victoria, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.clineuro.2013.11.015DOI Listing
February 2014

Clinical factors are significant predictors of outcome post intra-arterial therapy for acute ischaemic stroke: a review.

J Neuroradiol 2013 Dec 14;40(5):315-25. Epub 2013 Nov 14.

Austin Hospital, 145 Studley Road, Heidelberg, Victoria 3084, Australia.

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http://dx.doi.org/10.1016/j.neurad.2013.09.002DOI Listing
December 2013