Publications by authors named "Bernard Lassègue"

57Publications

β1 and β2 integrins: central players in regulating vascular permeability and leukocyte recruitment during acute inflammation.

Authors:
Ziwei Ou Elena V Dolmatova Bernard Lassegue Kathy K Griendling

Am J Physiol Heart Circ Physiol 2020 Dec 18. Epub 2020 Dec 18.

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December 2020

Correction: Platelet-derived growth factor (PDGF) regulates slingshot phosphatase activity via Nox1-dependent auto-dephosphorylation of serine 834 in vascular smooth muscle cells.

Authors:
Mithu Maheswaranathan Hope K A Gole Isabel Fernandez Bernard Lassègue Kathy K Griendling Alejandra San Martín

J Biol Chem 2020 Jun;295(24):8348

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June 2020

Poldip2 mediates blood-brain barrier disruption in a model of sepsis-associated encephalopathy.

Authors:
Daniel S Kikuchi Ana Carolina P Campos Hongyan Qu Steven J Forrester Rosana L Pagano Bernard Lassègue Ruxana T Sadikot Kathy K Griendling Marina S Hernandes

J Neuroinflammation 2019 Nov 28;16(1):241. Epub 2019 Nov 28.

Division of Cardiology, Department of Medicine, Emory University School of Medicine, 101 Woodruff Circle, 308 WMB, Atlanta, GA, 30322, USA.

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November 2019

Polymerase-δ-interacting protein 2 activates the RhoGEF epithelial cell transforming sequence 2 in vascular smooth muscle cells.

Authors:
Lauren Parker Huff Daniel Seicho Kikuchi Elizabeth Faidley Steven J Forrester Michelle Z Tsai Bernard Lassègue Kathy K Griendling

Am J Physiol Cell Physiol 2019 05 6;316(5):C621-C631. Epub 2019 Feb 6.

Department of Medicine, Division of Cardiology, Emory University School of Medicine , Atlanta, Georgia.

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May 2019

Poldip2 deficiency protects against lung edema and vascular inflammation in a model of acute respiratory distress syndrome.

Authors:
Steven J Forrester Qian Xu Daniel S Kikuchi Derick Okwan-Duodu Ana Carolina Campos Elizabeth A Faidley Guogang Zhang Bernard Lassègue Ruxana T Sadikot Kathy K Griendling Marina S Hernandes

Clin Sci (Lond) 2019 01 25;133(2):321-334. Epub 2019 Jan 25.

Division of Cardiology, Department of Medicine, Emory University, Atlanta, GA 30322, U.S.A.

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January 2019

NOX4 (NADPH Oxidase 4) and Poldip2 (Polymerase δ-Interacting Protein 2) Induce Filamentous Actin Oxidation and Promote Its Interaction With Vinculin During Integrin-Mediated Cell Adhesion.

Authors:
Sasa Vukelic Qian Xu Bonnie Seidel-Rogol Elizabeth A Faidley Anna E Dikalova Lula L Hilenski Ulrich Jorde Leslie B Poole Bernard Lassègue Guogang Zhang Kathy K Griendling

Arterioscler Thromb Vasc Biol 2018 10;38(10):2423-2434

From the Division of Cardiology, Department of Medicine, Emory University, Atlanta, GA (S.V., Q.X., B.S.-R., E.A.F., L.L.H., B.L., K.K.G.).

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October 2018

The cofilin phosphatase slingshot homolog 1 restrains angiotensin II-induced vascular hypertrophy and fibrosis in vivo.

Authors:
Holly C Williams Jing Ma Daiana Weiss Bernard Lassègue Roy L Sutliff Alejandra San Martín

Lab Invest 2019 03 5;99(3):399-410. Epub 2018 Oct 5.

Department of Medicine, Division of Cardiology, Emory University, Atlanta, GA, 30322, USA.

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March 2019

Poldip2 knockdown inhibits vascular smooth muscle proliferation and neointima formation by regulating the expression of PCNA and p21.

Authors:
Srinivasa Raju Datla Lula L Hilenski Bonnie Seidel-Rogol Anna E Dikalova Mark Harousseau Lili Punkova Giji Joseph W Robert Taylor Bernard Lassègue Kathy K Griendling

Lab Invest 2019 03 20;99(3):387-398. Epub 2018 Sep 20.

Department of Medicine, Division of Cardiology, Emory University, Atlanta, GA, 30322, USA.

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March 2019

Cyclic Strain and Hypertension Increase Osteopontin Expression in the Aorta.

Authors:
Christa Caesar Alicia N Lyle Giji Joseph Daiana Weiss Fadi M F Alameddine Bernard Lassègue Kathy K Griendling W Robert Taylor

Cell Mol Bioeng 2017 Apr 27;10(2):144-152. Epub 2016 Dec 27.

Division of Cardiology, Department of Medicine, Emory University School of Medicine, Atlanta, GA 30322, USA.

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April 2017

Polymerase delta-interacting protein 2 deficiency protects against blood-brain barrier permeability in the ischemic brain.

Authors:
Marina S Hernandes Bernard Lassègue Lula L Hilenski Jonathan Adams Ning Gao Chia-Yi Kuan Yu-Yo Sun Lihong Cheng Daniel S Kikuchi Manuel Yepes Kathy K Griendling

J Neuroinflammation 2018 Feb 17;15(1):45. Epub 2018 Feb 17.

Division of Cardiology, Department of Medicine, Emory University, 101 Woodruff Circle, 308 WMB, Atlanta, GA, 30322, USA.

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February 2018

Poldip2 is an oxygen-sensitive protein that controls PDH and αKGDH lipoylation and activation to support metabolic adaptation in hypoxia and cancer.

Authors:
Felipe Paredes Kely Sheldon Bernard Lassègue Holly C Williams Elizabeth A Faidley Gloria A Benavides Gloria Torres Fernanda Sanhueza-Olivares Samantha M Yeligar Kathy K Griendling Victor Darley-Usmar Alejandra San Martin

Proc Natl Acad Sci U S A 2018 02 6;115(8):1789-1794. Epub 2018 Feb 6.

Division of Cardiology, Department of Medicine, Emory University, Atlanta, GA 30322;

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February 2018

Design, synthesis, and biological evaluation of inhibitors of the NADPH oxidase, Nox4.

Authors:
Qian Xu Amol A Kulkarni Ayyiliath M Sajith Dilbi Hussein David Brown Osman F Güner M Damoder Reddy E Blake Watkins Bernard Lassègue Kathy K Griendling J Phillip Bowen

Bioorg Med Chem 2018 03 17;26(5):989-998. Epub 2017 Dec 17.

Department of Pharmaceutical Sciences, College of Pharmacy, Mercer University, Atlanta, GA 30341, USA. Electronic address:

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March 2018

Polymerase δ-interacting Protein 2: A Multifunctional Protein.

Authors:
Marina S Hernandes Bernard Lassègue Kathy K Griendling

J Cardiovasc Pharmacol 2017 Jun;69(6):335-342

Division of Cardiology, Department of Medicine, Emory University, Atlanta, GA.

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June 2017

NOX4-derived reactive oxygen species limit fibrosis and inhibit proliferation of vascular smooth muscle cells in diabetic atherosclerosis.

Authors:
Elyse Di Marco Stephen P Gray Kit Kennedy Cedric Szyndralewiez Alicia N Lyle Bernard Lassègue Kathy K Griendling Mark E Cooper Harald H H W Schmidt Karin A M Jandeleit-Dahm

Free Radic Biol Med 2016 08 19;97:556-567. Epub 2016 Jul 19.

Diabetic Complications Division, Baker IDI Heart & Diabetes Institute, Melbourne, Australia; Department of Medicine, Monash University, Melbourne, Australia. Electronic address:

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August 2016

Polymerase delta-interacting protein 2 regulates collagen accumulation via activation of the Akt/mTOR pathway in vascular smooth muscle cells.

Authors:
Masakazu Fujii Angélica Amanso Thalita B Abrahão Bernard Lassègue Kathy K Griendling

J Mol Cell Cardiol 2016 Mar 19;92:21-9. Epub 2016 Jan 19.

Division of Cardiology, Department of Medicine, Emory University, Atlanta, GA, United States. Electronic address:

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March 2016

Hic-5 Mediates TGFβ-Induced Adhesion in Vascular Smooth Muscle Cells by a Nox4-Dependent Mechanism.

Authors:
Isabel Fernandez Abel Martin-Garrido Dennis W Zhou Roza E Clempus Bonnie Seidel-Rogol Alejandra Valdivia Bernard Lassègue Andrés J García Kathy K Griendling Alejandra San Martin

Arterioscler Thromb Vasc Biol 2015 May 26;35(5):1198-206. Epub 2015 Mar 26.

From the Division of Cardiology, Department of Medicine, Emory University, Atlanta, GA (I.F., A.M.-G., R.E.C., B.S.-R., A.V., B.L., K.K.G., A.S.M.); and Woodruff School of Mechanical Engineering and Petit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, Atlanta (D.W.Z., A.J.G.).

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May 2015

Poldip2 controls vascular smooth muscle cell migration by regulating focal adhesion turnover and force polarization.

Authors:
Srinivasa Raju Datla Daniel J McGrail Sasa Vukelic Lauren P Huff Alicia N Lyle Lily Pounkova Minyoung Lee Bonnie Seidel-Rogol Mazen K Khalil Lula L Hilenski Lance S Terada Michelle R Dawson Bernard Lassègue Kathy K Griendling

Am J Physiol Heart Circ Physiol 2014 Oct 25;307(7):H945-57. Epub 2014 Jul 25.

Department of Medicine, Division of Cardiology, Emory University School of Medicine, Atlanta;

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October 2014

Polymerase δ-interacting protein 2 promotes postischemic neovascularization of the mouse hindlimb.

Authors:
Angélica M Amanso Bernard Lassègue Giji Joseph Natalia Landázuri James S Long Daiana Weiss W Robert Taylor Kathy K Griendling

Arterioscler Thromb Vasc Biol 2014 Jul 22;34(7):1548-55. Epub 2014 May 22.

From the Department of Medicine, Division of Cardiology (A.M.A., B.L., G.J., J.S.L., D.W., W.R.T., K.K.G.) and The Wallace H. Coulter Department of Biomedical Engineering (W.R.T.), Emory University, Atlanta, GA; and Department of Medicine, Division of Cardiology, Atlanta VA Medical Center, GA (W.R.T.).

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July 2014

Poldip2 knockout results in perinatal lethality, reduced cellular growth and increased autophagy of mouse embryonic fibroblasts.

Authors:
David I Brown Bernard Lassègue Minyoung Lee Rostam Zafari James S Long Harold I Saavedra Kathy K Griendling

PLoS One 2014 5;9(5):e96657. Epub 2014 May 5.

Department of Medicine, Division of Cardiology, Emory University School of Medicine, Atlanta, Georgia, United States of America.

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January 2015

Hydrogen peroxide regulates osteopontin expression through activation of transcriptional and translational pathways.

Authors:
Alicia N Lyle Ebony W Remus Aaron E Fan Bernard Lassègue Grant A Walter Arihiro Kiyosue Kathy K Griendling W Robert Taylor

J Biol Chem 2014 Jan 18;289(1):275-85. Epub 2013 Nov 18.

From the Division of Cardiology and.

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January 2014