Publications by authors named "Bernard Faller"

22Publications

Drug permeability profiling using cell-free permeation tools: Overview and applications.

Eur J Pharm Sci 2018 Jul 13;119:219-233. Epub 2018 Apr 13.

Drug Delivery and Disposition, KU Leuven, Gasthuisberg O&N II, Herestraat 49, Box 921, 3000 Leuven, Belgium. Electronic address:

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July 2018

Benefit of Retraining pKa Models Studied Using Internally Measured Data.

J Chem Inf Model 2015 Jul 29;55(7):1449-59. Epub 2015 Jun 29.

§Novartis Institute for Biomedical Research, 250 Massachusetts Ave, Cambridge, Massachusetts 02139, United States.

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July 2015

Evolution of the physicochemical properties of marketed drugs: can history foretell the future?

Drug Discov Today 2011 Nov 18;16(21-22):976-84. Epub 2011 Jul 18.

Novartis Institutes for BioMedical Research, Basel, Switzerland.

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November 2011

CYP3A time-dependent inhibition risk assessment validated with 400 reference drugs.

Drug Metab Dispos 2011 Jun 7;39(6):1039-46. Epub 2011 Mar 7.

Discovery ADME, Novartis Institutes for BioMedical Research, WSJ-350.3.12, P.O. Box, CH-4002 Basel, Switzerland.

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June 2011

What is modulating solubility in simulated intestinal fluids?

Eur J Pharm Sci 2010 Nov 23;41(3-4):452-7. Epub 2010 Jul 23.

Metabolism and Pharmacokinetics, Novartis Institutes for BioMedical Research, Basel, Switzerland.

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November 2010

Metabolic soft spot identification and compound optimization in early discovery phases using MetaSite and LC-MS/MS validation.

J Med Chem 2009 Jan;52(2):329-35

Novartis Institutes for BioMedical Research, Metabolism and Pharmacokinetics, Postfach, CH-4002, Basel, Switzerland.

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January 2009

Artificial membrane assays to assess permeability.

Authors:
Bernard Faller

Curr Drug Metab 2008 Nov;9(9):886-92

Novartis Institutes for BioMedical Research, Basel, Switzerland.

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November 2008

New approach to measure protein binding based on a parallel artificial membrane assay and human serum albumin.

J Med Chem 2008 Apr 19;51(7):2009-17. Epub 2008 Mar 19.

Departament de Química Analítica, Universitat de Barcelona, Martí i Franquès 1, Barcelona, Spain.

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April 2008

PAMPA--critical factors for better predictions of absorption.

J Pharm Sci 2007 Nov;96(11):2893-909

pION INC, 5 Constitution Way, Woburn, Massachusetts 01801, USA.

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November 2007

Computational approaches to determine drug solubility.

Adv Drug Deliv Rev 2007 Jul 26;59(7):533-45. Epub 2007 May 26.

Novartis Institutes for BioMedical Research, Novartis Campus, CH-4056 Basel, Basel, Switzerland.

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July 2007

Modeling promiscuity based on in vitro safety pharmacology profiling data.

ChemMedChem 2007 Jun;2(6):874-80

CPC/LFP/MLI, Novartis Institutes for Biomedical Research, Novartis Pharma AG, Postfach, 4002 Basel, Switzerland.

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June 2007

Alkylamides from Echinacea are a new class of cannabinomimetics. Cannabinoid type 2 receptor-dependent and -independent immunomodulatory effects.

J Biol Chem 2006 May 17;281(20):14192-206. Epub 2006 Mar 17.

Department of Chemistry and Applied Biosciences, ETH Zurich, Wolfgang-Pauli-Strasse 10, CH-8093 Zürich, Switzerland.

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May 2006