Bernard E Weissman

Bernard E Weissman

UNVERIFIED PROFILE

Are you Bernard E Weissman?   Register this Author

Register author
Bernard E Weissman

Bernard E Weissman

Publications by authors named "Bernard E Weissman"

Are you Bernard E Weissman?   Register this Author

32Publications

473Reads

5Profile Views

Remodeling the cancer epigenome: mutations in the SWI/SNF complex offer new therapeutic opportunities.

Expert Rev Anticancer Ther 2019 May 13;19(5):375-391. Epub 2019 May 13.

a Department of Pathology and Laboratory Medicine , University of North Carolina , Chapel Hill , NC , USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/14737140.2019.1605905DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6533634PMC
May 2019

NRF2 Activation in Cancer: From DNA to Protein.

Cancer Res 2019 Mar 13;79(5):889-898. Epub 2019 Feb 13.

Department of Cell Biology and Physiology, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, North Carolina.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/0008-5472.CAN-18-2723DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397706PMC
March 2019

High Frequency of Ovarian Cyst Development in Vhl;Snf5 Mice.

Am J Pathol 2018 07 22;188(7):1510-1516. Epub 2018 Apr 22.

Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, North Carolina; Department of Pathology and Laboratory Medicine, University of North Carolina, Chapel Hill, North Carolina. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ajpath.2018.03.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6024179PMC
July 2018

The histone methyltransferase EZH2 is a therapeutic target in small cell carcinoma of the ovary, hypercalcaemic type.

J Pathol 2017 07 2;242(3):371-383. Epub 2017 Jun 2.

Department of Pathology and Laboratory Medicine, University of British Columbia and Department of Molecular Oncology, British Columbia Cancer Research Centre, Vancouver, BC, Canada.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/path.4912
Publisher Site
http://dx.doi.org/10.1002/path.4912DOI Listing
July 2017

The chromatin-modifying protein HMGA2 promotes atypical teratoid/rhabdoid cell tumorigenicity.

J Neuropathol Exp Neurol 2015 Feb;74(2):177-85

From the Division of Neuropathology and Sidney Kimmel Comprehensive Cancer Center (HK, MH-C, MFW, CGE, EHR), Division of Pediatric Oncology (EHR), Johns Hopkins University School of Medicine, Bloomberg Children's Hospital, Baltimore, Maryland; Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, North Carolina (YK, BEW); and Division of Hematology, Oncology, and Blood and Bone Marrow Transplant, Children's Hospital Los Angeles (JX, AE-E); and the University of Southern California (AE-E), Los Angeles, California.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/NEN.0000000000000161DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4695975PMC
February 2015

SNF5/INI1 deficiency redefines chromatin remodeling complex composition during tumor development.

Mol Cancer Res 2014 Nov 9;12(11):1574-85. Epub 2014 Jul 9.

Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, North Carolina. Department of Pediatrics, Kyoto Prefectural University of Medicine, Kyoto, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1541-7786.MCR-14-0005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4233162PMC
November 2014

SWI/SNF chromatin remodeling complexes and cancer.

Am J Med Genet C Semin Med Genet 2014 Sep 28;166C(3):350-66. Epub 2014 Aug 28.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/ajmg.c.31410
Publisher Site
http://dx.doi.org/10.1002/ajmg.c.31410DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4516040PMC
September 2014

BRG1 mutations found in human cancer cell lines inactivate Rb-mediated cell-cycle arrest.

J Cell Physiol 2011 Aug;226(8):1989-97

Curriculum in Toxicology, University of North Carolina, Chapel Hill, North Carolina 27599-7295, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jcp.22533DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4433745PMC
August 2011

BRG1 co-localizes with DNA replication factors and is required for efficient replication fork progression.

Nucleic Acids Res 2010 Nov 22;38(20):6906-19. Epub 2010 Jun 22.

Department of Pathology and Laboratory Medicine, University of North Carolina, Chapel Hill, NC 27599, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/nar/gkq559DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2978342PMC
November 2010

Reexpression of hSNF5 in malignant rhabdoid tumor cell lines causes cell cycle arrest through a p21(CIP1/WAF1)-dependent mechanism.

Cancer Res 2010 Mar 23;70(5):1854-65. Epub 2010 Feb 23.

Department of Pathology and Laboratory Medicine, UNC Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599-7295, USA.

View Article

Download full-text PDF

Source
http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
Publisher Site
http://dx.doi.org/10.1158/0008-5472.CAN-09-1922DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2831128PMC
March 2010

Tumor-specific cooperation of retinoblastoma protein family and Snf5 inactivation.

Cancer Res 2007 Apr;67(7):3002-9

Department of Pathology and Laboratory Medicine, University of North Carolina, Chapel Hill, North Carolina, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/0008-5472.CAN-06-4207DOI Listing
April 2007

Loss of the hSNF5 gene concomitantly inactivates p21CIP/WAF1 and p16INK4a activity associated with replicative senescence in A204 rhabdoid tumor cells.

Cancer Res 2005 Nov;65(22):10192-8

Department of Pathology and Laboratory Medicine, University of North Carolina, Chapel Hill, North Carolina 27599-7295, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/0008-5472.CAN-05-1896DOI Listing
November 2005

SWI/SNF chromatin-remodeling factors induce changes in DNA methylation to promote transcriptional activation.

Cancer Res 2005 May;65(9):3542-7

Division of Neuroscience, Oregon National Primate Research Center, Oregon Health and Science University, Beaverton, Oregon 97006, USA.

View Article

Download full-text PDF

Source
http://cancerres.aacrjournals.org/lookup/doi/10.1158/0008-54
Publisher Site
http://dx.doi.org/10.1158/0008-5472.CAN-04-3554DOI Listing
May 2005

The expression of the SWI/SNF ATPase subunits BRG1 and BRM in normal human tissues.

Appl Immunohistochem Mol Morphol 2005 Mar;13(1):66-74

Division of Hematology/Oncology, University of Michigan, Ann Arbor, Michigan, USA.

View Article

Download full-text PDF

Source
March 2005

The Ews/Fli-1 fusion gene changes the status of p53 in neuroblastoma tumor cell lines.

Cancer Res 2004 Oct;64(20):7288-95

Curriculum in Toxicology and Department of Pathology and Laboratory Medicine, Lineberger Comprehensive Cancer Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/0008-5472.CAN-04-1610DOI Listing
October 2004

The Ews/Fli-1 fusion gene switches the differentiation program of neuroblastomas to Ewing sarcoma/peripheral primitive neuroectodermal tumors.

Cancer Res 2004 Feb;64(4):1266-77

Curriculum in Toxicology, Department of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC 27599, USA.

View Article

Download full-text PDF

Source
February 2004

Hybrid capture of putative tumor suppressor genes.

Methods Mol Biol 2003 ;222:365-73

Department of Pathology and Laboratory Medicine, University of North Carolina, Chapel Hill, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1385/1-59259-328-3:365DOI Listing
June 2003

Expression of Smad4 in the FaDu cell line partially restores TGF-beta growth inhibition but is not sufficient to regulate fibronectin expression or suppress tumorigenicity.

J Cell Physiol 2003 Mar;194(3):289-302

Curriculum in Toxicology, University of North Carolina, Chapel Hill, North Carolina 27599-7295, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jcp.10202DOI Listing
March 2003

Loss of BRG1/BRM in human lung cancer cell lines and primary lung cancers: correlation with poor prognosis.

Cancer Res 2003 Feb;63(3):560-6

Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, 27599-7295, USA.

View Article

Download full-text PDF

Source
February 2003

Re-expression of hSNF5/INI1/BAF47 in pediatric tumor cells leads to G1 arrest associated with induction of p16ink4a and activation of RB.

Oncogene 2002 Aug;21(34):5193-203

Department of Pathology and Laboratory Medicine and The Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, North Carolina, NC 27599, USA.

View Article

Download full-text PDF

Source
http://www.nature.com/articles/1205706
Publisher Site
http://dx.doi.org/10.1038/sj.onc.1205706DOI Listing
August 2002

Compensation of BRG-1 function by Brm: insight into the role of the core SWI-SNF subunits in retinoblastoma tumor suppressor signaling.

J Biol Chem 2002 Feb 21;277(7):4782-9. Epub 2001 Nov 21.

Department of Cell Biology, University of Cincinnati College of Medicine, Vontz Center for Molecular Studies, Cincinnati, Ohio 45267-0521, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M109532200DOI Listing
February 2002