Publications by authors named "Benjamin T Spike"

25Publications

Dachshund Depletion Disrupts Mammary Gland Development and Diverts the Composition of the Mammary Gland Progenitor Pool.

Stem Cell Reports 2019 01 13;12(1):135-151. Epub 2018 Dec 13.

Pennsylvania Cancer and Regenerative Medicine Research Center, Baruch S. Blumberg Institute, 3805 Old Easton Road, Doylestown, PA 18902, USA; Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore 637551, Singapore. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22136711183047
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http://dx.doi.org/10.1016/j.stemcr.2018.11.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6335505PMC
January 2019

Lgr5 is a marker for fetal mammary stem cells, but is not essential for stem cell activity or tumorigenesis.

NPJ Breast Cancer 2017 24;3:16. Epub 2017 Apr 24.

Salk Institute for Biological Studies, Gene Expression Laboratory, La Jolla, CA 92037 USA.

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http://www.nature.com/articles/s41523-017-0018-6
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http://dx.doi.org/10.1038/s41523-017-0018-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460261PMC
April 2017

Cell state plasticity, stem cells, EMT, and the generation of intra-tumoral heterogeneity.

NPJ Breast Cancer 2017 19;3:14. Epub 2017 Apr 19.

Huntsman Cancer Institute, The University of Utah, 2000 Circle of Hope, Salt Lake City, UT 84112 USA.

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http://dx.doi.org/10.1038/s41523-017-0012-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5460241PMC
April 2017

Sox10 Regulates Stem/Progenitor and Mesenchymal Cell States in Mammary Epithelial Cells.

Cell Rep 2015 Sep 10;12(12):2035-48. Epub 2015 Sep 10.

Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, CA 92037, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2015.08.040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4591253PMC
September 2015

Luminal progenitor and fetal mammary stem cell expression features predict breast tumor response to neoadjuvant chemotherapy.

Breast Cancer Res Treat 2015 Jan 10;149(2):425-37. Epub 2015 Jan 10.

Department of Pathology and Laboratory Medicine, University of North Carolina at Chapel Hill, Chapel Hill, NC, 27599, USA,

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http://dx.doi.org/10.1007/s10549-014-3262-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4308649PMC
January 2015

CRIPTO/GRP78 signaling maintains fetal and adult mammary stem cells ex vivo.

Stem Cell Reports 2014 Apr 3;2(4):427-39. Epub 2014 Apr 3.

Clayton Foundation Laboratories for Peptide Biology, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA.

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http://dx.doi.org/10.1016/j.stemcr.2014.02.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3986630PMC
April 2014

Stem cells and the developing mammary gland.

J Mammary Gland Biol Neoplasia 2013 Jun 27;18(2):209-19. Epub 2013 Apr 27.

Terry Fox Laboratory, British Columbia Cancer Agency, 675 West 10th Avenue, Vancouver, BC V5Z 1L3, Canada.

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http://dx.doi.org/10.1007/s10911-013-9284-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4161372PMC
June 2013

p53, Stem Cells, and Reprogramming: Tumor Suppression beyond Guarding the Genome.

Genes Cancer 2011 Apr;2(4):404-19

Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, CA, USA.

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http://dx.doi.org/10.1177/1947601911410224DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3135646PMC
April 2011

Inactivation of p53 in breast cancers correlates with stem cell transcriptional signatures.

Proc Natl Acad Sci U S A 2010 Dec 13;107(52):22745-50. Epub 2010 Dec 13.

The Simons Center for Systems Biology, Institute for Advanced Study, Princeton, NJ 08540, USA.

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http://dx.doi.org/10.1073/pnas.1017001108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3012457PMC
December 2010

Elevated poly-(ADP-ribose)-polymerase activity sensitizes retinoblastoma-deficient cells to DNA damage-induced necrosis.

Mol Cancer Res 2009 Jul 7;7(7):1099-109. Epub 2009 Jul 7.

The Ben May Department for Cancer Research, The Gordon Center for Integrative Sciences, The University of Chicago, Chicago, Illinois 60637, USA.

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http://dx.doi.org/10.1158/1541-7786.MCR-08-0439DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2994938PMC
July 2009

Deregulated E2f-2 underlies cell cycle and maturation defects in retinoblastoma null erythroblasts.

Mol Cell Biol 2007 Dec 8;27(24):8713-28. Epub 2007 Oct 8.

Ben May Department for Cancer Research, Gordon Center for Integrative Sciences, The University of Chicago, 929 East 57th Street, Chicago, IL 60637, USA.

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http://dx.doi.org/10.1128/MCB.01118-07DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2169398PMC
December 2007

Effects of hypoxia on heterotypic macrophage interactions.

Cell Cycle 2007 Nov 13;6(21):2620-4. Epub 2007 Aug 13.

The Ben May Department for Cancer Research, The University of Chicago, GCIS-W338, Chicago, Illinois 60637, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2989883PMC
http://dx.doi.org/10.4161/cc.6.21.4879DOI Listing
November 2007

BNIP3 is an RB/E2F target gene required for hypoxia-induced autophagy.

Mol Cell Biol 2007 Sep 18;27(17):6229-42. Epub 2007 Jun 18.

The Ben May Department for Cancer Research, The Gordon Center for Integrative Sciences, W-338, The University of Chicago, 929 E 57th St., Chicago, IL 60637, USA.

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http://dx.doi.org/10.1128/MCB.02246-06DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1952167PMC
September 2007

Hypoxic stress underlies defects in erythroblast islands in the Rb-null mouse.

Blood 2007 Sep 8;110(6):2173-81. Epub 2007 Jun 8.

Ben May Department for Cancer Research, Center for Integrative Sciences, Chicago, IL 60637, USA.

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http://dx.doi.org/10.1182/blood-2007-01-069104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1976369PMC
September 2007

Unrestrained erythroblast development in Nix-/- mice reveals a mechanism for apoptotic modulation of erythropoiesis.

Proc Natl Acad Sci U S A 2007 Apr 9;104(16):6794-9. Epub 2007 Apr 9.

Center for Molecular Cardiovascular Research and Department of Pediatrics, Children's Hospital Medical Center, University of Cincinnati, Cincinnati, OH 45267, USA.

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http://dx.doi.org/10.1073/pnas.0610666104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1849960PMC
April 2007

The Rb tumor suppressor in stress responses and hematopoietic homeostasis.

Cell Cycle 2005 Jan 29;4(1):42-5. Epub 2005 Jan 29.

Ben May Institute for Cancer Research, Knapp Medical Research Building, University of Chicago, Chicago Illinois, USA.

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http://dx.doi.org/10.4161/cc.4.1.1337DOI Listing
January 2005

The Rb tumor suppressor is required for stress erythropoiesis.

EMBO J 2004 Oct 30;23(21):4319-29. Epub 2004 Sep 30.

The Ben May Institute for Cancer Research, The University of Chicago, 924 East 57th Street, Chicago, IL 60637, USA.

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http://dx.doi.org/10.1038/sj.emboj.7600432DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC524396PMC
October 2004