Benjamin S Glicksberg

Benjamin S Glicksberg

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Benjamin S Glicksberg

Benjamin S Glicksberg

Publications by authors named "Benjamin S Glicksberg"

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42Publications

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Leveraging Big Data to Transform Drug Discovery.

Methods Mol Biol 2019 ;1939:91-118

Bakar Computational Health Sciences Institute, University of California, San Francisco, CA, USA.

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http://dx.doi.org/10.1007/978-1-4939-9089-4_6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6657335PMC
July 2019

Evaluating cell lines as models for metastatic breast cancer through integrative analysis of genomic data.

Nat Commun 2019 05 15;10(1):2138. Epub 2019 May 15.

Department of Pediatrics and Human Development, College of Human Medicine, Michigan State University, Grand Rapids, 49503, MI, USA.

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http://dx.doi.org/10.1038/s41467-019-10148-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520398PMC
May 2019

Robust prediction of clinical outcomes using cytometry data.

Bioinformatics 2019 Apr;35(7):1197-1203

Bakar Computational Health Sciences Institute, University of California, San Francisco, CA, USA.

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http://dx.doi.org/10.1093/bioinformatics/bty768DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449751PMC
April 2019

Lyme Disease Patient Trajectories Learned from Electronic Medical Data for Stratification of Disease Risk and Therapeutic Response.

Sci Rep 2019 Mar 14;9(1):4460. Epub 2019 Mar 14.

Department of Genetics and Genomic Sciences, Institute for Next Generation Healthcare, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place Box 1498, New York, NY, 10029, USA.

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http://dx.doi.org/10.1038/s41598-019-41128-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6418311PMC
March 2019

A call for deep-learning healthcare.

Nat Med 2019 Jan;25(1):14-15

Bakar Computational Health Sciences Institute, University of California San Francisco, San Francisco, CA, USA.

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http://www.nature.com/articles/s41591-018-0320-3
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http://dx.doi.org/10.1038/s41591-018-0320-3DOI Listing
January 2019

Selecting precise reference normal tissue samples for cancer research using a deep learning approach.

BMC Med Genomics 2019 Jan 31;12(Suppl 1):21. Epub 2019 Jan 31.

Institute for Computational Health Sciences, University of California, San Francisco, CA, USA.

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http://dx.doi.org/10.1186/s12920-018-0463-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357350PMC
January 2019

Evaluation of patient re-identification using laboratory test orders and mitigation via latent space variables.

Pac Symp Biocomput 2019 ;24:415-426

Institute for Next Generation Healthcare, Department of Genetics and Genomics Sciences, Icahn School of Medicine at Mount Sinai, 770 Lexington Ave 15th Fl., New York, NY 10065, USA*Authors contributed equally.

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January 2019

Loss-of-function of neuroplasticity-related genes confers risk for human neurodevelopmental disorders.

Pac Symp Biocomput 2018 ;23:68-79

Department of Neuroscience, Icahn School of Medicine at Mount Sinai, 1 Gustave L. Levy Pl. New York City, NY 10029, USA, ²Departments of Psychiatry and Opthamology, Icahn School of Medicine at Mount Sinai, 1 Gustave L. Levy Pl. New York City, NY 10029, USA, ³Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, 1 Gustave L. Levy Pl. New York City, NY 10029, USA, ⁴Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, 1 Gustave L. Levy Pl. New York City, NY 10029, USA, ⁵Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, 1 Gustave L. Levy Pl. New York City, NY 10029, USA, ⁶Institute for Next Generation Healthcare, Icahn School of Medicine at Mount Sinai, 1 Gustave L. Levy Pl. New York City, NY 10029, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5728668PMC
August 2018

Automated disease cohort selection using word embeddings from Electronic Health Records.

Pac Symp Biocomput 2018 ;23:145-156

Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, 1 Gustave L. Levy Pl. New York, NY 10065, USA, ²Institute for Next Generation Healthcare, Icahn School of Medicine at Mount Sinai, 1 Gustave L. Levy Pl. New York, NY 10065, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788312PMC
August 2018

Causal inference on electronic health records to assess blood pressure treatment targets: an application of the parametric g formula.

Pac Symp Biocomput 2018 ;23:180-191

Institute for Next Generation Healthcare, Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10065, US.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5728675PMC
August 2018

Adaptive Landscape of Protein Variation in Human Exomes.

Mol Biol Evol 2018 08;35(8):2015-2025

Institute for Genomics and Evolutionary Medicine, Temple University, Philadelphia, PA.

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http://dx.doi.org/10.1093/molbev/msy107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063297PMC
August 2018

Machine learning in cardiovascular medicine: are we there yet?

Heart 2018 07 19;104(14):1156-1164. Epub 2018 Jan 19.

Division of Cardiology, West Virginia Heart and Vascular Institute, Morgantown, West Virginia, USA.

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http://heart.bmj.com/lookup/doi/10.1136/heartjnl-2017-311198
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http://dx.doi.org/10.1136/heartjnl-2017-311198DOI Listing
July 2018

The whole is greater than the sum of its parts: combining classical statistical and machine intelligence methods in medicine.

Heart 2018 07;104(14):1228

Division of Cardiology, West Virginia Heart and Vascular Institute, Morgantown, West Virginia, USA.

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http://dx.doi.org/10.1136/heartjnl-2018-313377DOI Listing
July 2018

Artificial Intelligence in Cardiology.

J Am Coll Cardiol 2018 06;71(23):2668-2679

Institute for Next Generation Healthcare, Mount Sinai Health System, New York, New York; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York. Electronic address:

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http://dx.doi.org/10.1016/j.jacc.2018.03.521DOI Listing
June 2018

The next generation of precision medicine: observational studies, electronic health records, biobanks and continuous monitoring.

Hum Mol Genet 2018 05;27(R1):R56-R62

Institute for Next Generation Healthcare Department of Genetics and Genomic Sciences, Icahn Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, Mount Sinai Health System, New York City, NY 10029, USA.

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https://academic.oup.com/hmg/article/27/R1/R56/4969371
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http://dx.doi.org/10.1093/hmg/ddy114DOI Listing
May 2018

Predicting age by mining electronic medical records with deep learning characterizes differences between chronological and physiological age.

J Biomed Inform 2017 Dec 4;76:59-68. Epub 2017 Nov 4.

Department of Pharmacological Sciences, Mount Sinai Center for Bioinformatics, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY 10029, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15320464173024
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http://dx.doi.org/10.1016/j.jbi.2017.11.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716867PMC
December 2017

Data-Driven Identification of Risk Factors of Patient Satisfaction at a Large Urban Academic Medical Center.

PLoS One 2016 26;11(5):e0156076. Epub 2016 May 26.

Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, 770 Lexington Ave., 15th floor, New York, NY 10065, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0156076PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4881910PMC
July 2017

Enabling Precision Cardiology Through Multiscale Biology and Systems Medicine.

JACC Basic Transl Sci 2017 Jun 26;2(3):311-327. Epub 2017 Jun 26.

Institute for Next Generation Healthcare, Mount Sinai Health System, New York, New York.

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http://dx.doi.org/10.1016/j.jacbts.2016.11.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6034501PMC
June 2017

IDENTIFY CANCER DRIVER GENES THROUGH SHARED MENDELIAN DISEASE PATHOGENIC VARIANTS AND CANCER SOMATIC MUTATIONS.

Pac Symp Biocomput 2017 ;22:473-484

Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, 1 Gustave L. Levy Pl. New York City, NY 10029, USA.

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http://dx.doi.org/10.1142/9789813207813_0044DOI Listing
March 2017

Comparative analyses of population-scale phenomic data in electronic medical records reveal race-specific disease networks.

Bioinformatics 2016 06;32(12):i101-i110

Department of Genetics and Genomic Sciences Icahn Institute for Genomics and Multiscale Biology Harris Center for Precision Wellness, Icahn School of Medicine at Mount Sinai, New York City, NY 10029, USA Department of Population Health Science and Policy, New York City, NY 10029, USA.

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https://academic.oup.com/bioinformatics/article-lookup/doi/1
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http://dx.doi.org/10.1093/bioinformatics/btw282DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908366PMC
June 2016

A loss of function variant in CASP7 protects against Alzheimer's disease in homozygous APOE ε4 allele carriers.

BMC Genomics 2016 06 23;17 Suppl 2:445. Epub 2016 Jun 23.

Department of Genetics and Genomic Sciences, Icahn Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.

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http://dx.doi.org/10.1186/s12864-016-2725-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4928152PMC
June 2016

An integrative pipeline for multi-modal discovery of disease relationships.

Pac Symp Biocomput 2015 :407-18

Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, 1 Gustave L. Levy Pl. New York City, NY 10029, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4345399PMC
April 2016

EHDViz: clinical dashboard development using open-source technologies.

BMJ Open 2016 Mar 24;6(3):e010579. Epub 2016 Mar 24.

Harris Center for Precision Wellness, Icahn School of Medicine at Mount Sinai, Mount Sinai Health System, New York City, New York, USA Department of Genetics and Genomic Sciences, Icahn Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, Mount Sinai Health System, New York City, New York, USA Department of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, Mount Sinai Health System, New York City, New York, USA.

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http://dx.doi.org/10.1136/bmjopen-2015-010579DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4809078PMC
March 2016

Identification of type 2 diabetes subgroups through topological analysis of patient similarity.

Sci Transl Med 2015 Oct;7(311):311ra174

Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, 700 Lexington Ave., New York, NY 10065, USA. Department of Health Policy and Research, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.

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http://dx.doi.org/10.1126/scitranslmed.aaa9364DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4780757PMC
October 2015