Publications by authors named "Benjamin S Glicksberg"

72Publications

Cytotoxic lymphocytes are dysregulated in multisystem inflammatory syndrome in children.

medRxiv 2020 Sep 2. Epub 2020 Sep 2.

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http://dx.doi.org/10.1101/2020.08.29.20182899DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7480058PMC
September 2020

Anticoagulation, Bleeding, Mortality, and Pathology in Hospitalized Patients With COVID-19.

J Am Coll Cardiol 2020 10 26;76(16):1815-1826. Epub 2020 Aug 26.

The Zena and Michael A. Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, New York, New York; Centro Nacional de Investigaciones Cardiovasculares Carlos III (CNIC), Madrid, Spain. Electronic address:

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http://dx.doi.org/10.1016/j.jacc.2020.08.041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7449655PMC
October 2020

Atypical lymphocyte morphology in SARS-CoV-2 infection.

Pathol Res Pract 2020 09 10;216(9):153063. Epub 2020 Jun 10.

Department of Pathology, Molecular and Cell-Based Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, United States.

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http://dx.doi.org/10.1016/j.prp.2020.153063DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7284261PMC
September 2020

SARS-CoV-2 viral load predicts COVID-19 mortality.

Lancet Respir Med 2020 09 6;8(9):e70. Epub 2020 Aug 6.

Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA. Electronic address:

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http://dx.doi.org/10.1016/S2213-2600(20)30354-4DOI Listing
September 2020

Deep representation learning of electronic health records to unlock patient stratification at scale.

NPJ Digit Med 2020 17;3:96. Epub 2020 Jul 17.

Hasso Plattner Institute for Digital Health at Mount Sinai, Icahn School of Medicine at Mount Sinai, New York, NY USA.

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http://dx.doi.org/10.1038/s41746-020-0301-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7367859PMC
July 2020

Identification of therapeutic targets from genetic association studies using hierarchical component analysis.

BioData Min 2020 17;13. Epub 2020 Jun 17.

Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029 USA.

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http://dx.doi.org/10.1186/s13040-020-00216-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7301559PMC
June 2020

Derivation and Validation of Genome Wide Polygenic Score for Urinary Tract Stone Diagnosis.

Kidney Int 2020 Jun 12. Epub 2020 Jun 12.

The Charles Bronfman Institute for Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA; The BioMe Phenomics Center, Icahn School of Medicine at Mount Sinai, New York, NY, USA; The Hasso Plattner Institute for Digital Health at Mount Sinai, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Division of Nephrology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Renal Program, James J Peters VA Medical Center at Bronx, New York, NY, USA. Electronic address:

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http://dx.doi.org/10.1016/j.kint.2020.04.055DOI Listing
June 2020

Machine Learning in Cardiology-Ensuring Clinical Impact Lives Up to the Hype.

J Cardiovasc Pharmacol Ther 2020 Sep 4;25(5):379-390. Epub 2020 Jun 4.

Hasso Plattner Institute for Digital Health at Mount Sinai, Icahn School of Medicine at Mount Sinai, New York, NY, USA.

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http://dx.doi.org/10.1177/1074248420928651DOI Listing
September 2020

Sleep in the Natural Environment: A Pilot Study.

Sensors (Basel) 2020 Mar 3;20(5). Epub 2020 Mar 3.

Hasso Plattner Institute for Digital Health at Mount Sinai, Icahn School of Medicine at Mount Sinai, New York, NY 10032, USA.

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http://dx.doi.org/10.3390/s20051378DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7085707PMC
March 2020

Identifying Acute Low Back Pain Episodes in Primary Care Practice From Clinical Notes: Observational Study.

JMIR Med Inform 2020 Feb 27;8(2):e16878. Epub 2020 Feb 27.

Department of Environmental Medicine and Public Health, Icahn School of Medicine at Mount Sinai, New York, NY, United States.

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http://dx.doi.org/10.2196/16878DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7068466PMC
February 2020

ROMOP: a light-weight R package for interfacing with OMOP-formatted electronic health record data.

JAMIA Open 2019 Apr 4;2(1):10-14. Epub 2019 Jan 4.

Department of Pediatrics Bakar Computational Health Sciences Institute, University of California San Francisco, San Francisco, California, USA.

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http://dx.doi.org/10.1093/jamiaopen/ooy059DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6800657PMC
April 2019

Evaluating cell lines as models for metastatic breast cancer through integrative analysis of genomic data.

Nat Commun 2019 05 15;10(1):2138. Epub 2019 May 15.

Department of Pediatrics and Human Development, College of Human Medicine, Michigan State University, Grand Rapids, 49503, MI, USA.

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http://dx.doi.org/10.1038/s41467-019-10148-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6520398PMC
May 2019

Lyme Disease Patient Trajectories Learned from Electronic Medical Data for Stratification of Disease Risk and Therapeutic Response.

Sci Rep 2019 03 14;9(1):4460. Epub 2019 Mar 14.

Department of Genetics and Genomic Sciences, Institute for Next Generation Healthcare, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place Box 1498, New York, NY, 10029, USA.

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http://dx.doi.org/10.1038/s41598-019-41128-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6418311PMC
March 2019

Evaluation of patient re-identification using laboratory test orders and mitigation via latent space variables.

Pac Symp Biocomput 2019 ;24:415-426

Institute for Next Generation Healthcare, Department of Genetics and Genomics Sciences, Icahn School of Medicine at Mount Sinai, 770 Lexington Ave 15th Fl., New York, NY 10065, USA*Authors contributed equally.

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February 2020

Leveraging Big Data to Transform Drug Discovery.

Methods Mol Biol 2019 ;1939:91-118

Bakar Computational Health Sciences Institute, University of California, San Francisco, CA, USA.

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http://dx.doi.org/10.1007/978-1-4939-9089-4_6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6657335PMC
July 2019

Selecting precise reference normal tissue samples for cancer research using a deep learning approach.

BMC Med Genomics 2019 01 31;12(Suppl 1):21. Epub 2019 Jan 31.

Institute for Computational Health Sciences, University of California, San Francisco, CA, USA.

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http://dx.doi.org/10.1186/s12920-018-0463-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357350PMC
January 2019

A call for deep-learning healthcare.

Nat Med 2019 Jan;25(1):14-15

Bakar Computational Health Sciences Institute, University of California San Francisco, San Francisco, CA, USA.

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http://www.nature.com/articles/s41591-018-0320-3
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http://dx.doi.org/10.1038/s41591-018-0320-3DOI Listing
January 2019

Robust prediction of clinical outcomes using cytometry data.

Bioinformatics 2019 04;35(7):1197-1203

Bakar Computational Health Sciences Institute, University of California, San Francisco, CA, USA.

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http://dx.doi.org/10.1093/bioinformatics/bty768DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6449751PMC
April 2019

The whole is greater than the sum of its parts: combining classical statistical and machine intelligence methods in medicine.

Heart 2018 07;104(14):1228

Division of Cardiology, West Virginia Heart and Vascular Institute, Morgantown, West Virginia, USA.

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http://dx.doi.org/10.1136/heartjnl-2018-313377DOI Listing
July 2018

Artificial Intelligence in Cardiology.

J Am Coll Cardiol 2018 06;71(23):2668-2679

Institute for Next Generation Healthcare, Mount Sinai Health System, New York, New York; Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, New York. Electronic address:

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http://dx.doi.org/10.1016/j.jacc.2018.03.521DOI Listing
June 2018

Adaptive Landscape of Protein Variation in Human Exomes.

Mol Biol Evol 2018 08;35(8):2015-2025

Institute for Genomics and Evolutionary Medicine, Temple University, Philadelphia, PA.

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http://dx.doi.org/10.1093/molbev/msy107DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6063297PMC
August 2018

The next generation of precision medicine: observational studies, electronic health records, biobanks and continuous monitoring.

Hum Mol Genet 2018 05;27(R1):R56-R62

Institute for Next Generation Healthcare Department of Genetics and Genomic Sciences, Icahn Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, Mount Sinai Health System, New York City, NY 10029, USA.

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https://academic.oup.com/hmg/article/27/R1/R56/4969371
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http://dx.doi.org/10.1093/hmg/ddy114DOI Listing
May 2018

Machine learning in cardiovascular medicine: are we there yet?

Heart 2018 07 19;104(14):1156-1164. Epub 2018 Jan 19.

Division of Cardiology, West Virginia Heart and Vascular Institute, Morgantown, West Virginia, USA.

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http://heart.bmj.com/lookup/doi/10.1136/heartjnl-2017-311198
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http://dx.doi.org/10.1136/heartjnl-2017-311198DOI Listing
July 2018

Causal inference on electronic health records to assess blood pressure treatment targets: an application of the parametric g formula.

Pac Symp Biocomput 2018 ;23:180-191

Institute for Next Generation Healthcare, Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10065, US.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5728675PMC
August 2018

Automated disease cohort selection using word embeddings from Electronic Health Records.

Pac Symp Biocomput 2018 ;23:145-156

Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, 1 Gustave L. Levy Pl. New York, NY 10065, USA, ²Institute for Next Generation Healthcare, Icahn School of Medicine at Mount Sinai, 1 Gustave L. Levy Pl. New York, NY 10065, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5788312PMC
August 2018

Loss-of-function of neuroplasticity-related genes confers risk for human neurodevelopmental disorders.

Pac Symp Biocomput 2018 ;23:68-79

Department of Neuroscience, Icahn School of Medicine at Mount Sinai, 1 Gustave L. Levy Pl. New York City, NY 10029, USA, ²Departments of Psychiatry and Opthamology, Icahn School of Medicine at Mount Sinai, 1 Gustave L. Levy Pl. New York City, NY 10029, USA, ³Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, 1 Gustave L. Levy Pl. New York City, NY 10029, USA, ⁴Friedman Brain Institute, Icahn School of Medicine at Mount Sinai, 1 Gustave L. Levy Pl. New York City, NY 10029, USA, ⁵Mindich Child Health and Development Institute, Icahn School of Medicine at Mount Sinai, 1 Gustave L. Levy Pl. New York City, NY 10029, USA, ⁶Institute for Next Generation Healthcare, Icahn School of Medicine at Mount Sinai, 1 Gustave L. Levy Pl. New York City, NY 10029, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5728668PMC
August 2018

Predicting age by mining electronic medical records with deep learning characterizes differences between chronological and physiological age.

J Biomed Inform 2017 Dec 4;76:59-68. Epub 2017 Nov 4.

Department of Pharmacological Sciences, Mount Sinai Center for Bioinformatics, Icahn School of Medicine at Mount Sinai, One Gustave L. Levy Place, New York, NY 10029, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15320464173024
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http://dx.doi.org/10.1016/j.jbi.2017.11.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5716867PMC
December 2017

Enabling Precision Cardiology Through Multiscale Biology and Systems Medicine.

JACC Basic Transl Sci 2017 Jun 26;2(3):311-327. Epub 2017 Jun 26.

Institute for Next Generation Healthcare, Mount Sinai Health System, New York, New York.

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http://dx.doi.org/10.1016/j.jacbts.2016.11.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6034501PMC
June 2017

IDENTIFY CANCER DRIVER GENES THROUGH SHARED MENDELIAN DISEASE PATHOGENIC VARIANTS AND CANCER SOMATIC MUTATIONS.

Pac Symp Biocomput 2017 ;22:473-484

Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, 1 Gustave L. Levy Pl. New York City, NY 10029, USA.

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http://dx.doi.org/10.1142/9789813207813_0044DOI Listing
March 2017

A loss of function variant in CASP7 protects against Alzheimer's disease in homozygous APOE ε4 allele carriers.

BMC Genomics 2016 06 23;17 Suppl 2:445. Epub 2016 Jun 23.

Department of Genetics and Genomic Sciences, Icahn Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.

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http://dx.doi.org/10.1186/s12864-016-2725-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4928152PMC
June 2016

Comparative analyses of population-scale phenomic data in electronic medical records reveal race-specific disease networks.

Bioinformatics 2016 06;32(12):i101-i110

Department of Genetics and Genomic Sciences Icahn Institute for Genomics and Multiscale Biology Harris Center for Precision Wellness, Icahn School of Medicine at Mount Sinai, New York City, NY 10029, USA Department of Population Health Science and Policy, New York City, NY 10029, USA.

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https://academic.oup.com/bioinformatics/article-lookup/doi/1
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http://dx.doi.org/10.1093/bioinformatics/btw282DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4908366PMC
June 2016

Data-Driven Identification of Risk Factors of Patient Satisfaction at a Large Urban Academic Medical Center.

PLoS One 2016 26;11(5):e0156076. Epub 2016 May 26.

Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, 770 Lexington Ave., 15th floor, New York, NY 10065, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0156076PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4881910PMC
July 2017

EHDViz: clinical dashboard development using open-source technologies.

BMJ Open 2016 Mar 24;6(3):e010579. Epub 2016 Mar 24.

Harris Center for Precision Wellness, Icahn School of Medicine at Mount Sinai, Mount Sinai Health System, New York City, New York, USA Department of Genetics and Genomic Sciences, Icahn Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, Mount Sinai Health System, New York City, New York, USA Department of Population Health Science and Policy, Icahn School of Medicine at Mount Sinai, Mount Sinai Health System, New York City, New York, USA.

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http://dx.doi.org/10.1136/bmjopen-2015-010579DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4809078PMC
March 2016

Identification of type 2 diabetes subgroups through topological analysis of patient similarity.

Sci Transl Med 2015 Oct;7(311):311ra174

Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, 700 Lexington Ave., New York, NY 10065, USA. Department of Health Policy and Research, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.

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http://dx.doi.org/10.1126/scitranslmed.aaa9364DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4780757PMC
October 2015

An integrative pipeline for multi-modal discovery of disease relationships.

Pac Symp Biocomput 2015 :407-18

Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, 1 Gustave L. Levy Pl. New York City, NY 10029, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4345399PMC
April 2016