Publications by authors named "Benjamin R Saville"

72Publications

Therapy development for the mucopolysaccharidoses: Updated consensus recommendations for neuropsychological endpoints.

Mol Genet Metab 2020 Aug 31. Epub 2020 Aug 31.

Department of Pediatrics, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA; Shapiro Neuropsychology Consulting LLC, Portland, OR, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ymgme.2020.08.007DOI Listing
August 2020

Comparison of response adaptive randomization features in multiarm clinical trials with control.

Pharm Stat 2020 09 21;19(5):602-612. Epub 2020 Mar 21.

Berry Consultants, Austin, Texas, USA.

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http://dx.doi.org/10.1002/pst.2015DOI Listing
September 2020

Choosing primary endpoints for clinical trials of health care interventions.

Contemp Clin Trials Commun 2019 Dec 12;16:100486. Epub 2019 Nov 12.

Wesfarmers Centre for Vaccines and Infectious Diseases, Telethon Kids Institute, University of Western Australia, Nedlands, Australia.

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http://dx.doi.org/10.1016/j.conctc.2019.100486DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6881606PMC
December 2019

Comparison of methods for control allocation in multiple arm studies using response adaptive randomization.

Clin Trials 2020 02 19;17(1):52-60. Epub 2019 Oct 19.

Berry Consultants LLC, Austin, TX, USA.

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http://dx.doi.org/10.1177/1740774519877836DOI Listing
February 2020

Commentary on Ji et al: Sub-optimal illustration of response adaptive randomization.

Clin Trials 2019 12 3;16(6):610-612. Epub 2019 Oct 3.

Berry Consultants, Austin, TX, USA.

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http://dx.doi.org/10.1177/1740774519875968DOI Listing
December 2019

Trial Refresh: A Case for an Adaptive Platform Trial for Pulmonary Exacerbations of Cystic Fibrosis.

Front Pharmacol 2019 28;10:301. Epub 2019 Mar 28.

Wesfarmers Centre of Vaccines & Infectious Diseases, Telethon Kids Institute, The University of Western Australia, Nedlands, WA, Australia.

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http://dx.doi.org/10.3389/fphar.2019.00301DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6447696PMC
March 2019

Research Note: Adaptive trials.

J Physiother 2019 04 26;65(2):113-116. Epub 2019 Mar 26.

Wesfarmers Centre of Vaccines & Infectious Diseases, Telethon Kids Institute, Perth, Australia; School of Public Health, Curtin University, Bentley, Perth, Australia; Department of Infectious Diseases, Perth Children's Hospital, Nedlands, Perth, Australia; Menzies School of Health Research and Charles Darwin University, Darwin, Australia.

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http://dx.doi.org/10.1016/j.jphys.2019.02.004DOI Listing
April 2019

Answering patient-centred questions efficiently: response-adaptive platform trials in primary care.

Br J Gen Pract 2018 06;68(671):294-295

Julius Center for Health Sciences and Primary Care, University Medical Center Utrecht, Utrecht, the Netherlands.

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http://dx.doi.org/10.3399/bjgp18X696569DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6002006PMC
June 2018

Fractures in the Pediatric Emergency Department: Are We Considering Abuse?

Clin Pediatr (Phila) 2018 09 16;57(10):1161-1167. Epub 2018 Feb 16.

1 Vanderbilt University, Nashville, TN, USA.

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http://dx.doi.org/10.1177/0009922818759319DOI Listing
September 2018

Effect of Weight Extremes on Ventricular Volumes and Myocardial Strain in Repaired Tetralogy of Fallot as Measured by CMR.

Pediatr Cardiol 2018 Mar 14;39(3):575-584. Epub 2017 Dec 14.

Division of Pediatric Cardiology, Department of Pediatrics, Vanderbilt University Medical Center, 2200 Children's Way, Suite 5230 Doctors' Office Tower, Nashville, TN, 37232, USA.

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http://link.springer.com/10.1007/s00246-017-1793-4
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http://dx.doi.org/10.1007/s00246-017-1793-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5831485PMC
March 2018

Randomization-based adjustment of multiple treatment hazard ratios for covariates with missing data.

J Biopharm Stat 2017 8;27(3):373-386. Epub 2017 Feb 8.

e International Drug Development Institute , Raleigh , North Carolina , USA.

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http://dx.doi.org/10.1080/10543406.2017.1289954DOI Listing
January 2018

Balanced covariates with response adaptive randomization.

Pharm Stat 2017 05 6;16(3):210-217. Epub 2017 Mar 6.

Berry Consultants, Austin, TX, 78746, USA.

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http://dx.doi.org/10.1002/pst.1803DOI Listing
May 2017

Does Body Mass Index Predict Premature Cardiomyopathy Onset for Duchenne Muscular Dystrophy?

J Child Neurol 2017 04 13;32(5):499-504. Epub 2017 Jan 13.

1 Thomas P. Graham Division of Pediatric Cardiology Monroe Carell Jr Children's Hospital at Vanderbilt University, Nashville, TN, USA.

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http://dx.doi.org/10.1177/0883073816687422DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5352486PMC
April 2017

Efficiencies of platform clinical trials: A vision of the future.

Clin Trials 2016 06 17;13(3):358-66. Epub 2016 Feb 17.

Berry Consultants, Austin, TX, USA Adjunct faculty, University of Kansas Medical Center, Department of Biostatistics, KS, USA.

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http://dx.doi.org/10.1177/1740774515626362DOI Listing
June 2016

Analysis of Risk of Recurrence by Subtype in ≤ 1-cm Breast Tumors.

Clin Breast Cancer 2016 Jun 6;16(3):223-31. Epub 2015 Nov 6.

Vanderbilt-Ingram Cancer Center, Nashville, TN.

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http://dx.doi.org/10.1016/j.clbc.2015.10.001DOI Listing
June 2016

Sensitivity analysis for missing outcomes in time-to-event data with covariate adjustment.

J Biopharm Stat 2016 30;26(2):269-79. Epub 2015 Jan 30.

c Biostatistics , University of North Carolina , Chapel Hill , North Carolina , USA.

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http://dx.doi.org/10.1080/10543406.2014.1000549DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4821499PMC
December 2016

Decision curve analysis.

JAMA 2015 Jan;313(4):409-10

Berry Consultants, Austin, Texas3Department of Emergency Medicine, Harbor-UCLA Medical Center, Torrance, California4Los Angeles Biomedical Research Institute, Torrance, California5David Geffen School of Medicine, University of California, Los Angeles.

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http://jama.jamanetwork.com/article.aspx?doi=10.1001/jama.20
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http://dx.doi.org/10.1001/jama.2015.37DOI Listing
January 2015

Human rhinovirus C infections in pediatric hematology and oncology patients.

Pediatr Transplant 2015 Feb 6;19(1):94-100. Epub 2014 Nov 6.

Center for Biomedical Ethics and Society, Vanderbilt University School of Medicine, Nashville, TN, USA.

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http://dx.doi.org/10.1111/petr.12383DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4280346PMC
February 2015

Association of blood products administration during cardiopulmonary bypass and excessive post-operative bleeding in pediatric cardiac surgery.

Pediatr Cardiol 2015 Mar 8;36(3):459-67. Epub 2014 Oct 8.

Pediatrics, University of New Mexico, MSC10 5590, Albuquerque, NM, 87131-0001, USA,

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http://dx.doi.org/10.1007/s00246-014-1034-zDOI Listing
March 2015

Evaluation of post-contrast myocardial t1 in duchenne muscular dystrophy using cardiac magnetic resonance imaging.

Pediatr Cardiol 2015 Jan 29;36(1):49-56. Epub 2014 Jul 29.

Division of Pediatric Cardiology, Department of Pediatrics, Vanderbilt University Medical Center, 2200 Children's Way, Suite 5230 DOT, Nashville, TN, 37232, USA,

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http://dx.doi.org/10.1007/s00246-014-0963-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4439095PMC
January 2015

The utility of Bayesian predictive probabilities for interim monitoring of clinical trials.

Clin Trials 2014 Aug 28;11(4):485-493. Epub 2014 May 28.

Department of Biostatistics, School of Medicine, Vanderbilt University, Nashville, TN, USA.

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http://journals.sagepub.com/doi/10.1177/1740774514531352
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http://dx.doi.org/10.1177/1740774514531352DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4247348PMC
August 2014

Predicting persistence of functional abdominal pain from childhood into young adulthood.

Clin Gastroenterol Hepatol 2014 Dec 13;12(12):2026-32. Epub 2014 Apr 13.

Division of Adolescent and Young Adult Health, Department of Pediatrics, Vanderbilt University Monroe Carell Jr. Children's Hospital at Vanderbilt, Nashville, Tennessee. Electronic address:

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http://dx.doi.org/10.1016/j.cgh.2014.03.034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4195814PMC
December 2014

Children with invasive Staphylococcus aureus disease exhibit a potently neutralizing antibody response to the cytotoxin LukAB.

Infect Immun 2014 Mar 30;82(3):1234-42. Epub 2013 Dec 30.

Department of Pediatrics, Division of Pediatric Infectious Diseases, The Monroe Carell Jr. Children's Hospital at Vanderbilt, and the Vanderbilt University School of Medicine, Nashville, Tennessee, USA.

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http://dx.doi.org/10.1128/IAI.01558-13DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3957992PMC
March 2014

Clinical predictors of autoimmune and severe atopic disease in pediatric heart transplant recipients.

Pediatr Transplant 2014 Mar 28;18(2):197-203. Epub 2013 Dec 28.

Division of Pediatric Cardiology, Department of Pediatrics, Vanderbilt University Medical Center, Nashville, TN, USA.

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http://dx.doi.org/10.1111/petr.12205DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988248PMC
March 2014

Postoperative complications and association with outcomes in pediatric cardiac surgery.

J Thorac Cardiovasc Surg 2014 Aug 23;148(2):609-16.e1. Epub 2013 Nov 23.

Department of Cardiothoracic Surgery, Monroe Carell Jr Children's Hospital at Vanderbilt, Nashville, Tenn.

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http://dx.doi.org/10.1016/j.jtcvs.2013.10.031DOI Listing
August 2014

Outcomes following infliximab therapy for pediatric patients hospitalized with refractory colitis-predominant IBD.

J Pediatr Gastroenterol Nutr 2014 Feb;58(2):213-9

*Department of Pediatrics †Department of Biostatistics ‡Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN.

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http://dx.doi.org/10.1097/MPG.0b013e3182a98df2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3946904PMC
February 2014

Residual lesions in postoperative pediatric cardiac surgery patients receiving extracorporeal membrane oxygenation support.

J Thorac Cardiovasc Surg 2014 Jan 15;147(1):434-41. Epub 2013 Apr 15.

Department of Pediatrics, Monroe Carell Jr. Children's Hospital at Vanderbilt, Nashville, Tenn.

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http://dx.doi.org/10.1016/j.jtcvs.2013.03.021DOI Listing
January 2014

Aminophylline infusion for status asthmaticus in the pediatric critical care unit setting is independently associated with increased length of stay and time for symptom improvement.

Pulm Pharmacol Ther 2014 Feb 19;27(1):57-61. Epub 2013 Mar 19.

Vanderbilt University School of Medicine, Department of, Pediatrics, Division of Emergency Medicine, USA; Center for Asthma & Environmental Sciences Research, USA. Electronic address:

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http://dx.doi.org/10.1016/j.pupt.2013.03.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3732550PMC
February 2014

Estimating covariate-adjusted log hazard ratios in randomized clinical trials using cox proportional hazards models and nonparametric randomization based analysis of covariance.

J Biopharm Stat 2013 Mar;23(2):477-90

Department of Biostatistics, Vanderbilt University School of Medicine, Nashville, TN 37232-2158 USA.

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http://dx.doi.org/10.1080/10543406.2012.755692DOI Listing
March 2013

Generic levothyroxine compared with synthroid in young children with congenital hypothyroidism.

J Clin Endocrinol Metab 2013 Feb 4;98(2):653-8. Epub 2013 Jan 4.

Department of Pediatrics, Division of Endocrinology, Vanderbilt University School of Medicine, Nashville, Tennessee 37232-9170, USA.

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http://dx.doi.org/10.1210/jc.2012-3558DOI Listing
February 2013

Preventability of early readmissions at a children's hospital.

Pediatrics 2013 Jan 10;131(1):e171-81. Epub 2012 Dec 10.

Department of Pediatrics, University of Texas Southwestern School of Medicine, Dallas, Texas 37232-9225, USA.

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http://dx.doi.org/10.1542/peds.2012-0820DOI Listing
January 2013

How much is enough? Evaluation of adrenal function in children who undergo growth hormone stimulation test.

J Pediatr Endocrinol Metab 2012 ;25(7-8):733-9

Ian Burr Division of Pediatric Endocrinology, Vanderbilt University Medical School, Nashville, TN 37232, USA.

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http://dx.doi.org/10.1515/jpem-2011-0457DOI Listing
January 2013

Human rhinovirus C: Age, season, and lower respiratory illness over the past 3 decades.

J Allergy Clin Immunol 2013 Jan 10;131(1):69-77.e1-6. Epub 2012 Nov 10.

Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, TN 37232, USA.

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http://dx.doi.org/10.1016/j.jaci.2012.09.033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3748586PMC
January 2013

Relationship between maternal and neonatal Staphylococcus aureus colonization.

Pediatrics 2012 May 2;129(5):e1252-9. Epub 2012 Apr 2.

Division of Pediatric Infectious Diseases, Vanderbilt University Medical Center, Nashville, Tennessee 37232, USA.

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http://dx.doi.org/10.1542/peds.2011-2308DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3340589PMC
May 2012

Ketamine sedation is not associated with clinically meaningful elevation of intraocular pressure.

Am J Emerg Med 2012 Sep 12;30(7):1215-8. Epub 2011 Dec 12.

Pediatric Emergency Medicine, Vanderbilt Children's Hospital, Nashville, TN 37232-9001, USA.

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http://dx.doi.org/10.1016/j.ajem.2011.06.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3761376PMC
September 2012

Assessing variance components in multilevel linear models using approximate Bayes factors: A case study of ethnic disparities in birthweight.

J R Stat Soc Ser A Stat Soc 2011 07;174(3):785-804

Department of Biostatistics, Vanderbilt University School of Medicine S-2323 Medical Center North, 1161 21st Avenue South Nashville, TN 37232-2158,

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http://dx.doi.org/10.1111/j.1467-985X.2011.00685.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3784317PMC
July 2011

Epidemiology of 15-Day Readmissions to a Children's Hospital.

Pediatrics 2011 Jun 9;127(6):e1505-12. Epub 2011 May 9.

Department of Pediatrics, Vanderbilt University School of Medicine, Nashville, TN 37232-9760, USA.

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http://dx.doi.org/10.1542/peds.2010-1737DOI Listing
June 2011

Improvement in antenatal diagnosis of critical congenital heart disease implications for postnatal care and screening.

Fetal Diagn Ther 2011 28;30(3):180-3. Epub 2011 Apr 28.

Department of Pediatrics, Monroe Carell Jr. Children's Hospital at Vanderbilt University, 2200 Children's Way, Nashville, TN 37232, USA.

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http://dx.doi.org/10.1159/000327148DOI Listing
June 2012

Improving education under work-hour restrictions: comparing learning and teaching preferences of faculty, residents, and students.

J Surg Educ 2010 Sep-Oct;67(5):290-6

Department of Surgery, Division of Plastic Surgery, University of North Carolina, Chapel Hill, North Carolina, USA.

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http://dx.doi.org/10.1016/j.jsurg.2010.07.001DOI Listing
February 2011

The effectiveness of baby books for providing pediatric anticipatory guidance to new mothers.

Pediatrics 2010 May 12;125(5):997-1002. Epub 2010 Apr 12.

Department of Education, University of California, Irvine, CA 92697-5500, USA.

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http://pediatrics.aappublications.org/cgi/doi/10.1542/peds.2
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http://dx.doi.org/10.1542/peds.2009-2728DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2875122PMC
May 2010

Graphical displays for clarifying how allocation ratio affects total sample size for the two sample logrank test.

Pharm Stat 2011 Jan-Feb;10(1):40-4

Department of Biostatistics, Vanderbilt University School of Medicine, Nashville, TN 37232-2158, USA.

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http://dx.doi.org/10.1002/pst.407DOI Listing
May 2011

A robust method for comparing two treatments in a confirmatory clinical trial via multivariate time-to-event methods that jointly incorporate information from longitudinal and time-to-event data.

Stat Med 2010 Jan;29(1):75-85

Department of Biostatistics, Vanderbilt University School of Medicine, S-2323 Medical Center North, Nashville, TN 37232-2158, USA.

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http://dx.doi.org/10.1002/sim.3740DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3146347PMC
January 2010

Mood stabilization and destabilization during acute and continuation phase treatment for bipolar I disorder with lamotrigine or placebo.

J Clin Psychiatry 2009 Sep 11;70(9):1273-80. Epub 2009 Aug 11.

Affective Disorders Program, Silver Hill Hospital, New Canaan, Connecticut, USA.

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http://dx.doi.org/10.4088/JCP.08m04381DOI Listing
September 2009

Testing random effects in the linear mixed model using approximate bayes factors.

Biometrics 2009 Jun;65(2):369-76

Department of Biostatistics, Vanderbilt University School of Medicine, S-2323 Medical Center North, Nashville, Tennessee 37232-2158, USA.

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http://doi.wiley.com/10.1111/j.1541-0420.2008.01107.x
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http://dx.doi.org/10.1111/j.1541-0420.2008.01107.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3136354PMC
June 2009

Racial differences in pain during 1 year among women with metastatic breast cancer: a hazards analysis of interval-censored data.

Cancer 2008 Jan;112(1):162-70

Cecil G. Sheps Center for Health Services Research, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599, USA.

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http://dx.doi.org/10.1002/cncr.23133DOI Listing
January 2008

The effect of cage size on reproductive performance and behavior of C57BL/6 mice.

Lab Anim (NY) 2007 Nov;36(10):32-9

Division of Laboratory Animal Medicine, Department of Pathology and Laboratory Medicine, 1100 Bioinformatics, CB# 7115, University of North Carolina, Chapel Hill, NC 27599, USA.

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http://dx.doi.org/10.1038/laban1107-32DOI Listing
November 2007

Hazards for pain severity and pain interference with daily living, with exploration of brief pain inventory cutpoints, among women with metastatic breast cancer.

J Pain Symptom Manage 2007 Oct 21;34(4):380-92. Epub 2007 Jun 21.

Department of Epidemiology, School of Public Health, and Cecil G. Sheps Center for Health Services Research, University of North Carolina, 725 Martin Luther King Jr. Boulevard, Chapel Hill, NC 27599, USA.

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http://dx.doi.org/10.1016/j.jpainsymman.2006.12.007DOI Listing
October 2007