Benjamin Ory

Laboratory of Regenerative Nanomedicine (RNM), INSERM U 1260, CRBS, Rue Eugène Boeckel, 67000, Strasbourg, France; Sino-French Joint Lab of Food Nutrition/Safety and Medicinal Chemistry, College of Biotechnology, Tianjin University of Science and Technology, Tianjin, China. Electronic address:

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January 2021

Sarcoma treatment in the era of molecular medicine.

EMBO Mol Med 2020 11 13;12(11):e11131. Epub 2020 Oct 13.

Department of Oncology and Metabolism, University of Sheffield, Sheffield, UK.

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November 2020

Ribosomopathies: New Therapeutic Perspectives.

Authors:

Emilien Orgebin François Lamoureux Bertrand Isidor Céline Charrier Benjamin Ory Frédéric Lézot Marc Baud'huin

Cells 2020 09 11;9(9). Epub 2020 Sep 11.

INSERM, Bone sarcomas and remodeling of calcified tissues, Nantes Université, UMR 1238, F-44000 Nantes, France.

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September 2020

N6-Adenosine Methylation of miRNA-200b-3p Influences Its Functionality and Is a Theranostic Tool.

Authors:

Joséphine Briand Aurélien A Sérandour Arulraj Nadaradjane Gwenola Bougras-Cartron Dominique Heymann Benjamin Ory François M Vallette Pierre-François Cartron

Mol Ther Nucleic Acids 2020 Aug 14;22:72-83. Epub 2020 Aug 14.

CRCINA, INSERM, Université de Nantes, Nantes, France; Equipe Apoptose et Progression Tumorale, LaBCT, Institut de Cancérologie de l'Ouest, Saint Herblain, France; Cancéropole Grand-Ouest, Réseau Niches et Epigénétique des Tumeurs (NET), Nantes, France; EpiSAVMEN Network (Région Pays de la Loire), Nantes, France; LabEX IGO, Université de Nantes, Nantes, France. Electronic address:

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August 2020

MicroRNA-17-5p Reduces Inflammation and Bone Erosions in Mice With Collagen-Induced Arthritis and Directly Targets the JAK/STAT Pathway in Rheumatoid Arthritis Fibroblast-like Synoviocytes.

Authors:

Aurélie Najm François-Marie Masson Pauline Preuss Steven Georges Benjamin Ory Thibaut Quillard Shatakshi Sood Carl S Goodyear Douglas J Veale Ursula Fearon Benoit Le Goff Frédéric Blanchard

Arthritis Rheumatol 2020 12 29;72(12):2030-2039. Epub 2020 Oct 29.

PHY-OS Laboratory, INSERM UMR 1238, Nantes University of Medicine, Nantes, France.

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December 2020

Implication of the p53-Related miR-34c, -125b, and -203 in the Osteoblastic Differentiation and the Malignant Transformation of Bone Sarcomas.

Authors:

Camille Jacques Robel Tesfaye Melanie Lavaud Steven Georges Marc Baud'huin François Lamoureux Benjamin Ory

Cells 2020 03 27;9(4). Epub 2020 Mar 27.

INSERM, Bone sarcomas and remodeling of calcified tissues, Nantes Université, UMR 1238, F-44000 Nantes, France.

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March 2020

TH1579, MTH1 inhibitor, delays tumour growth and inhibits metastases development in osteosarcoma model.

Authors:

Brice Moukengue Hannah K Brown Céline Charrier Séverine Battaglia Marc Baud'huin Thibaut Quillard Therese M Pham Ioannis S Pateras Vassilis G Gorgoulis Thomas Helleday Dominique Heymann Ulrika Warpman Berglund Benjamin Ory Francois Lamoureux

EBioMedicine 2020 Mar 7;53:102704. Epub 2020 Mar 7.

Université de Nantes, INSERM, U1238, Sarcomes osseux et remodelage des tissus calcifiés, Team 3, Epistress, Rue Gaston Veil, 44035 Nantes cedex, France. Electronic address:

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March 2020

Cytosine methylation of mature microRNAs inhibits their functions and is associated with poor prognosis in glioblastoma multiforme.

Authors:

Mathilde Cheray Amandine Etcheverry Camille Jacques Romain Pacaud Gwenola Bougras-Cartron Marc Aubry Florent Denoual Pierre Peterlongo Arulraj Nadaradjane Joséphine Briand Farida Akcha Dominique Heymann François M Vallette Jean Mosser Benjamin Ory Pierre-François Cartron

Mol Cancer 2020 02 25;19(1):36. Epub 2020 Feb 25.

CRCINA, INSERM, Université de Nantes, Nantes, France.

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February 2020

BET bromodomains' functions in bone-related pathologies.

Authors:

Camille Jacques Melanie Lavaud Steven Georges Robel Tesfaye Marc Baud'huin François Lamoureux Benjamin Ory

Epigenomics 2020 01 18;12(2):127-144. Epub 2019 Dec 18.

Nantes Université, INSERM, Bone sarcomas & remodeling of calcified tissues, UMR 1238, F-44000 Nantes, France.

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January 2020

RPL13 Variants Cause Spondyloepimetaphyseal Dysplasia with Severe Short Stature.

Am J Hum Genet 2019 11 17;105(5):1040-1047. Epub 2019 Oct 17.

CHU Nantes, Service de génétique médicale, F-44000 Nantes, France. Electronic address:

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November 2019

Murine Models of Bone Sarcomas.

Authors:

Camille Jacques Nathalie Renema Benjamin Ory Carl R Walkley Agamemnon E Grigoriadis Dominique Heymann

Methods Mol Biol 2019 ;1914:331-342

Institut de Cancérologie de l'Ouest, INSERM, UMR1232, Université de Nantes, Université d'Angers, Tumour Heterogeneity and Precision Medicine, Nantes, France.

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June 2019

Analysis of mRNA, miRNA, and DNA in Bone Cells by RT-qPCR and In Situ Hybridization.

Authors:

Brice Moukengue Jérôme Amiaud Camille Jacques Céline Charrier Benjamin Ory Francois Lamoureux

Methods Mol Biol 2019 ;1914:169-196

INSERM, UMR1238, Bone Sarcoma and Remodeling of Calcified Tissues, Université de Nantes, Nantes Atlantique Universités, Nantes, France.

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June 2019

Loss of miR-198 and -206 during primary tumor progression enables metastatic dissemination in human osteosarcoma.

Authors:

Steven Georges Lidia Rodriguez Calleja Camille Jacques Melanie Lavaud Brice Moukengue Fernando Lecanda Thibaut Quillard Marta Tellez Gabriel Pierre-François Cartron Marc Baud'huin François Lamoureux Dominique Heymann Benjamin Ory

Oncotarget 2018 Nov 6;9(87):35726-35741. Epub 2018 Nov 6.

INSERM, UMR-S 1238, Nantes 44035, France.

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November 2018

Small animal models for the study of bone sarcoma pathogenesis:characteristics, therapeutic interests and limitations.

Authors:

Camille Jacques Nathalie Renema Frederic Lezot Benjamin Ory Carl R Walkley Agi E Grigoriadis Dominique Heymann

J Bone Oncol 2018 Sep 21;12:7-13. Epub 2018 Feb 21.

University of Sheffield, Medical School, Dept of Oncology and Metabolism. INSERM, European Associated laboratory «Sarcoma Research Unit», Beech Hill Road, S10 2RX Sheffield, UK.

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September 2018

Identification of genomic differences among peripheral arterial beds in atherosclerotic and healthy arteries.

Authors:

Marja Steenman Olivier Espitia Blandine Maurel Beatrice Guyomarch Marie-Françoise Heymann Marc-Antoine Pistorius Benjamin Ory Dominique Heymann Rémi Houlgatte Yann Gouëffic Thibaut Quillard

Sci Rep 2018 03 2;8(1):3940. Epub 2018 Mar 2.

UMR1238 INSERM, Université de Nantes, CHU de Nantes, Nantes, France.

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March 2018

Implication of molecular vascular smooth muscle cell heterogeneity among arterial beds in arterial calcification.

Authors:

Olivier Espitia Mathias Chatelais Marja Steenman Céline Charrier Blandine Maurel Steven Georges Rémi Houlgatte Franck Verrecchia Benjamin Ory François Lamoureux Dominique Heymann Yann Gouëffic Thibaut Quillard

PLoS One 2018 26;13(1):e0191976. Epub 2018 Jan 26.

INSERM, UMR 1238, Nantes, France; Université de Nantes, Nantes Atlantique Universités, Laboratoire « Sarcome osseux et remodelage des tissus osseux calcifiés », Faculté de Médecine, Nantes, France.

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March 2018

Tumour Heterogeneity: The Key Advantages of Single-Cell Analysis.

Authors:

Marta Tellez-Gabriel Benjamin Ory Francois Lamoureux Marie-Francoise Heymann Dominique Heymann

Int J Mol Sci 2016 Dec 20;17(12). Epub 2016 Dec 20.

Institut National de la Santé et de la Recherche Médicale (INSERM), Unit 957, Pathophysiology of Bone Resorption and Therapy of Primary Bone Tumours, Equipe Ligue 2012, Faculty of Medicine, University of Nantes, Nantes 44035, France.

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December 2016

Inhibition of BET proteins and epigenetic signaling as a potential treatment for osteoporosis.

Authors:

Marc Baud'huin François Lamoureux Camille Jacques Lidia Rodriguez Calleja Thibaut Quillard Céline Charrier Jérome Amiaud Martine Berreur Bénédicte Brounais-LeRoyer Robert Owen Gwendolen C Reilly James E Bradner Dominique Heymann Benjamin Ory

Bone 2017 01 23;94:10-21. Epub 2016 Sep 23.

INSERM, UMR 957, équipe labellisée ligue 2012, 1 Rue Gaston Veil, 44035 Nantes, France; Physiopathologie de la Résorption Osseuse et Thérapie des Tumeurs Osseuses Primitives, Université de Nantes, Nantes Atlantique Universités, EA3822, 1 Rue Gaston Veil, 44035 Nantes, France. Electronic address:

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January 2017

miRNA-193a-5p repression of p73 controls Cisplatin chemoresistance in primary bone tumors.

Authors:

Camille Jacques Lidia Rodriguez Calleja Marc Baud'huin Thibaut Quillard Dominique Heymann François Lamoureux Benjamin Ory

Oncotarget 2016 Aug;7(34):54503-54514

INSERM, UMR 957, Équipe Labellisée Ligue 2012, Nantes, France.

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August 2016

Protein-altering MYH3 variants are associated with a spectrum of phenotypes extending to spondylocarpotarsal synostosis syndrome.

Authors:

Raphael Carapito Alice Goldenberg Nicodème Paul Angélique Pichot Albert David Antoine Hamel Clémentine Dumant-Forest Julien Leroux Benjamin Ory Bertrand Isidor Seiamak Bahram

Eur J Hum Genet 2016 12 6;24(12):1746-1751. Epub 2016 Jul 6.

Plateforme GENOMAX, Laboratoire d'ImmunoRhumatologie Moléculaire, INSERM UMR_S1109, Centre de Recherche d'Immunologie et d'Hématologie, Faculté de Médecine, Fédération Hospitalo-Universitaire OMICARE, Fédération de Médecine Translationnelle de Strasbourg (FMTS), Université de Strasbourg, Strasbourg, France.

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December 2016

Targeting the epigenetic readers in Ewing sarcoma inhibits the oncogenic transcription factor EWS/Fli1.

Authors:

Camille Jacques François Lamoureux Marc Baud'huin Lidia Rodriguez Calleja Thibaut Quillard Jérôme Amiaud Franck Tirode Françoise Rédini James E Bradner Dominique Heymann Benjamin Ory

Oncotarget 2016 Apr;7(17):24125-40

INSERM, UMR 957, Équipe Labellisée Ligue 2012, Nantes, France.

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April 2016

ΔNp63α Silences a miRNA Program to Aberrantly Initiate a Wound-Healing Program That Promotes TGFβ-Induced Metastasis.

Authors:

Lidia Rodriguez Calleja Camille Jacques François Lamoureux Marc Baud'huin Marta Tellez Gabriel Thibaut Quillard Debashish Sahay Pierre Perrot Jerome Amiaud Celine Charrier Regis Brion Fernando Lecanda Franck Verrecchia Dominique Heymann Leif W Ellisen Benjamin Ory

Cancer Res 2016 06 17;76(11):3236-51. Epub 2016 Mar 17.

INSERM, UMR-S 957, Nantes, Equipe labellisée LIGUE 2012, France. Physiopathologie de la Résorption Osseuse et Thérapie des Tumeurs Osseuses Primitives, Université de Nantes, Nantes Atlantique Universités, Rue Gaston Veil, Nantes, France.

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June 2016

Circulating Tumor Cells: A Review of Non-EpCAM-Based Approaches for Cell Enrichment and Isolation.

Authors:

Marta Tellez Gabriel Lidia Rodriguez Calleja Antoine Chalopin Benjamin Ory Dominique Heymann

Clin Chem 2016 Apr 19;62(4):571-81. Epub 2016 Feb 19.

INSERM, UMR 957, Equipe LIGUE Nationale Contre le Cancer 2012, Nantes, France; Université de Nantes, Nantes Atlantique Universités, Pathophysiology of Bone Resorption and Therapy of Primary Bone Tumours, Nantes, France; CHU de Nantes, Nantes, France; Department of Oncology and Metabolism, University of Sheffield, Sheffield, UK.

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April 2016

Blocking HSP90 Addiction Inhibits Tumor Cell Proliferation, Metastasis Development, and Synergistically Acts with Zoledronic Acid to Delay Osteosarcoma Progression.

Authors:

Benjamin Ory Marc Baud'huin Franck Verrecchia Bénédicte Brounais-Le Royer Thibaut Quillard Jérôme Amiaud Séverine Battaglia Dominique Heymann Francoise Redini Francois Lamoureux

Clin Cancer Res 2016 05 28;22(10):2520-33. Epub 2015 Dec 28.

Université de Nantes, Nantes atlantique universités, Laboratoire de Physiopathologie de la Résorption Osseuse et Thérapie des Tumeurs Osseuses Primitives, Nantes, France. INSERM, UMR 957, Nantes, France. LUNAM Université, Nantes, France. Equipe labellisée LIGUE 2012, Nantes, France.

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May 2016

Clusterin inhibition using OGX-011 synergistically enhances zoledronic acid activity in osteosarcoma.

Authors:

Francois Lamoureux Marc Baud'huin Benjamin Ory Romain Guiho Amina Zoubeidi Martin Gleave Dominique Heymann Françoise Rédini

Oncotarget 2014 Sep;5(17):7805-19

Université de Nantes, Nantes atlantique universités, Laboratoire de Physiopathologie de la Résorption Osseuse et Thérapie des Tumeurs Osseuses Primitives, Nantes F-44035, France. INSERM, UMR 957, Nantes F-44035, France. LUNAM Université. Equipe labellisée LIGUE 2012, Nantes, cedex.

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September 2014

BYL719, a new α-specific PI3K inhibitor: single administration and in combination with conventional chemotherapy for the treatment of osteosarcoma.

Authors:

Bérengère Gobin Marc Baud' Huin François Lamoureux Benjamin Ory Céline Charrier Rachel Lanel Séverine Battaglia Françoise Redini Frédéric Lezot Frédéric Blanchard Dominique Heymann

Int J Cancer 2015 Feb 30;136(4):784-96. Epub 2014 Jun 30.

INSERM, UMR 957, Nantes, 44035, France; Université de Nantes, Physiopathologie de la Résorption Osseuse et Thérapie des Tumeurs Osseuses Primitives, Nantes, 44035, France.

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February 2015

Selective inhibition of BET bromodomain epigenetic signalling interferes with the bone-associated tumour vicious cycle.

Authors:

François Lamoureux Marc Baud'huin Lidia Rodriguez Calleja Camille Jacques Martine Berreur Françoise Rédini Fernando Lecanda James E Bradner Dominique Heymann Benjamin Ory

Nat Commun 2014 Mar 19;5:3511. Epub 2014 Mar 19.

1] INSERM, UMR 957, Équipe labellisée ligue 2012, 1 Rue Gaston Veil, Nantes 44035, France [2] Physiopathologie de la Résorption Osseuse et Thérapie des Tumeurs Osseuses Primitives, Université de Nantes, Nantes Atlantique Universités, EA3822, 1 Rue Gaston Veil, Nantes 44035, France.

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March 2014

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