Benjamin J Doranz

Benjamin J Doranz

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Benjamin J Doranz

Benjamin J Doranz

Publications by authors named "Benjamin J Doranz"

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Analysis of a Therapeutic Antibody Cocktail Reveals Determinants for Cooperative and Broad Ebolavirus Neutralization.

Immunity 2020 Feb 4;52(2):388-403.e12. Epub 2020 Feb 4.

Vanderbilt Vaccine Center, Vanderbilt University Medical Center, Nashville, TN 37232, USA; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN 37232, USA; Department of Pediatrics, Vanderbilt University Medical Center, Nashville, TN 37232, USA. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2020.01.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7111202PMC
February 2020

Potent neutralizing antibodies elicited by dengue vaccine in rhesus macaque target diverse epitopes.

PLoS Pathog 2019 06 6;15(6):e1007716. Epub 2019 Jun 6.

Texas Therapeutics Institute, Brown Foundation Institute of Molecular Medicine, University of Texas Health Science Center at Houston, Houston, Texas, United States of America.

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http://dx.doi.org/10.1371/journal.ppat.1007716DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6553876PMC
June 2019

Multifunctional Pan-ebolavirus Antibody Recognizes a Site of Broad Vulnerability on the Ebolavirus Glycoprotein.

Immunity 2018 08 17;49(2):363-374.e10. Epub 2018 Jul 17.

Vanderbilt Vaccine Center, Vanderbilt University Medical Center, Nashville, TN 37232, USA; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Nashville, TN 37232, USA; Chemical and Physical Biology Program, Vanderbilt University, Nashville, TN 37232, USA; Department of Pediatrics, Vanderbilt University Medical Center, Nashville, TN 37232, USA. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2018.06.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6104738PMC
August 2018

Human antibody recognition of antigenic site IV on Pneumovirus fusion proteins.

PLoS Pathog 2018 02 22;14(2):e1006837. Epub 2018 Feb 22.

Vanderbilt Vaccine Center, Vanderbilt University Medical Center, Nashville, Tennessee, United States of America.

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http://dx.doi.org/10.1371/journal.ppat.1006837DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823459PMC
February 2018

A Biologically-validated HCV E1E2 Heterodimer Structural Model.

Sci Rep 2017 03 16;7(1):214. Epub 2017 Mar 16.

Laboratory of Microbiology and Virology, Università "Vita-Salute" San Raffaele, Via Olgettina 58, 20132, Milano, Italy.

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http://dx.doi.org/10.1038/s41598-017-00320-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5428263PMC
March 2017

Dengue Virus prM-Specific Human Monoclonal Antibodies with Virus Replication-Enhancing Properties Recognize a Single Immunodominant Antigenic Site.

J Virol 2016 01 28;90(2):780-9. Epub 2015 Oct 28.

Department of Pediatrics, Vanderbilt University Medical Center, Vanderbilt University, Nashville, Tennessee, USA Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Vanderbilt University, Nashville, Tennessee, USA The Vanderbilt Vaccine Center, Vanderbilt University Medical Center, Vanderbilt University, Nashville, Tennessee, USA

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http://jvi.asm.org/content/early/2015/10/22/JVI.01805-15.ful
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http://jvi.asm.org/content/90/2/780.full.pdf
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http://jvi.asm.org/lookup/doi/10.1128/JVI.01805-15
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http://dx.doi.org/10.1128/JVI.01805-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4702676PMC
January 2016

Cross-Reactive and Potent Neutralizing Antibody Responses in Human Survivors of Natural Ebolavirus Infection.

Cell 2016 Jan 21;164(3):392-405. Epub 2016 Jan 21.

Department of Pathology, Microbiology and Immunology, Vanderbilt University, Nashville, TN 37232, USA; Department of Pediatrics, Vanderbilt University, Nashville, TN 37232, USA; Vanderbilt Vaccine Center, Vanderbilt University, Nashville, TN 37232, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2015.12.022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4733404PMC
January 2016

Neutralizing Monoclonal Antibodies Block Chikungunya Virus Entry and Release by Targeting an Epitope Critical to Viral Pathogenesis.

Cell Rep 2015 Dec 10;13(11):2553-2564. Epub 2015 Dec 10.

Blood Systems Research Institute, San Francisco, CA 94118, USA; Department of Laboratory Medicine, University of California, San Francisco, San Francisco, CA 94143, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2015.11.043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4720387PMC
December 2015

Broadly Neutralizing Alphavirus Antibodies Bind an Epitope on E2 and Inhibit Entry and Egress.

Cell 2015 Nov 6;163(5):1095-1107. Epub 2015 Nov 6.

Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA; Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA; Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO 63110, USA; Center for Human Immunology and Immunotherapy Programs, Washington University School of Medicine, St. Louis, MO 63110, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2015.10.050DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4659373PMC
November 2015

Isolation and Characterization of Broad and Ultrapotent Human Monoclonal Antibodies with Therapeutic Activity against Chikungunya Virus.

Cell Host Microbe 2015 Jul;18(1):86-95

Department of Pediatrics, Vanderbilt University Medical Center, Vanderbilt University, Nashville, TN 37232, USA; Department of Pathology, Microbiology, and Immunology, Vanderbilt University Medical Center, Vanderbilt University, Nashville, TN 37232, USA; Vanderbilt Vaccine Center, Vanderbilt University Medical Center, Vanderbilt University, Nashville, TN 37232, USA. Electronic address:

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http://dx.doi.org/10.1016/j.chom.2015.06.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4501771PMC
July 2015

HCV E2 core structures and mAbs: something is still missing.

Drug Discov Today 2014 Dec 27;19(12):1964-70. Epub 2014 Aug 27.

Laboratory of Microbiology and Virology, Università "Vita-Salute" San Raffaele, Milano, Italy. Electronic address:

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http://dx.doi.org/10.1016/j.drudis.2014.08.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4706463PMC
December 2014

A high-throughput shotgun mutagenesis approach to mapping B-cell antibody epitopes.

Immunology 2014 Sep;143(1):13-20

Integral Molecular Inc., Philadelphia, PA, USA.

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http://dx.doi.org/10.1111/imm.12323DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4137951PMC
September 2014

A neutralizing monoclonal antibody targeting the acid-sensitive region in chikungunya virus E2 protects from disease.

PLoS Negl Trop Dis 2013 12;7(9):e2423. Epub 2013 Sep 12.

Blood Systems Research Institute, San Francisco, California, United States of America ; Department of Laboratory Medicine, University of California, San Francisco, San Francisco, California, United States of America.

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http://dx.doi.org/10.1371/journal.pntd.0002423DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3772074PMC
March 2014

Dengue virus envelope protein domain I/II hinge determines long-lived serotype-specific dengue immunity.

Proc Natl Acad Sci U S A 2014 Feb 2;111(5):1939-44. Epub 2014 Jan 2.

Department of Molecular Microbiology and Immunology and Division of Infectious Diseases, Department of Medicine, Oregon Health and Sciences University, Portland, OR 97239.

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http://dx.doi.org/10.1073/pnas.1317350111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3918811PMC
February 2014

Maturation of the Gag core decreases the stability of retroviral lipid membranes.

Virology 2012 Nov 17;433(2):401-9. Epub 2012 Sep 17.

Integral Molecular, Inc., Philadelphia, PA 19104, United States.

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http://dx.doi.org/10.1016/j.virol.2012.08.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3848701PMC
November 2012

Measuring membrane protein interactions using optical biosensors.

Methods Mol Biol 2010 ;617:445-56

Integral Molecular, Inc, Philadelphia, PA, USA.

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http://dx.doi.org/10.1007/978-1-60327-323-7_32DOI Listing
June 2010

Atomic-level mapping of antibody epitopes on a GPCR.

J Am Chem Soc 2009 May;131(20):6952-4

Integral Molecular, Inc., 3701 Market Street, Fourth Floor, Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.1021/ja900186nDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2943208PMC
May 2009

Virus-like particles as quantitative probes of membrane protein interactions.

Biochemistry 2008 Jul 14;47(27):6988-90. Epub 2008 Jun 14.

Integral Molecular, Inc., 3701 Market Street, Suite 340, Philadelphia, Pennsylvania 19104, USA.

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http://dx.doi.org/10.1021/bi800540bDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2741162PMC
July 2008

Cell-free assay of G-protein-coupled receptors using fluorescence polarization.

J Biomol Screen 2008 Jun;13(5):424-9

Biologics and Biomolecular Sciences, Boehringer Ingelheim Pharmaceuticals, Inc., Ridgefield, Connecticut 06488, USA.

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http://dx.doi.org/10.1177/1087057108318332DOI Listing
June 2008

The core domain of chemokines binds CCR5 extracellular domains while their amino terminus interacts with the transmembrane helix bundle.

J Biol Chem 2003 Feb 3;278(7):5179-87. Epub 2002 Dec 3.

Institute of Interdisciplinary Research, Université Libre de Bruxelles, Campus Erasme, 808 route de Lennik, B-1070 Brussels, Belgium.

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http://dx.doi.org/10.1074/jbc.M205684200DOI Listing
February 2003