Benjamin D Canan

Benjamin D Canan

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Benjamin D Canan

Benjamin D Canan

Publications by authors named "Benjamin D Canan"

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Association of Genetic Polymorphisms in the Beta-1 Adrenergic Receptor with Recovery of Left Ventricular Ejection Fraction in Patients with Heart Failure.

J Cardiovasc Transl Res 2019 Aug 12;12(4):280-289. Epub 2019 Feb 12.

Division of Cardiovascular Medicine, Department of Internal Medicine, Ohio State University College of Medicine, Columbus, OH, USA.

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http://dx.doi.org/10.1007/s12265-019-09866-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6690812PMC
August 2019

Stretching Single Titin Molecules from Failing Human Hearts Reveals Titin's Role in Blunting Cardiac Kinetic Reserve.

Cardiovasc Res 2019 Feb 18. Epub 2019 Feb 18.

Department of Physiology and Cell Biology, Cairo, Egypt.

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http://dx.doi.org/10.1093/cvr/cvz043DOI Listing
February 2019

Force-frequency relationship and early relaxation kinetics are preserved upon sarcoplasmic blockade in human myocardium.

Physiol Rep 2018 10;6(20):e13898

Department of Physiology and Cell Biology, The Ohio State University Wexner Medical Center, Columbus, Ohio.

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http://dx.doi.org/10.14814/phy2.13898DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6198135PMC
October 2018

Impaired adhesion of induced pluripotent stem cell-derived cardiac progenitor cells (iPSC-CPCs) to isolated extracellular matrix from failing hearts.

Heliyon 2018 Oct 18;4(10):e00870. Epub 2018 Oct 18.

The University of New Mexico College of Pharmacy, Department of Pharmaceutical Sciences, MSC09 5360, 1 University of New Mexico, Albuquerque, NM 87131, USA.

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http://dx.doi.org/10.1016/j.heliyon.2018.e00870DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197956PMC
October 2018

Human Myocardium Has a Robust α1A-Subtype Adrenergic Receptor Inotropic Response.

J Cardiovasc Pharmacol 2018 09;72(3):136-142

Veterans Affairs Medical Center, San Francisco, Department of Medicine, University of California San Francisco, San Francisco, CA.

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http://dx.doi.org/10.1097/FJC.0000000000000604DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6126952PMC
September 2018

Etiology-dependent impairment of relaxation kinetics in right ventricular end-stage failing human myocardium.

J Mol Cell Cardiol 2018 08 5;121:81-93. Epub 2018 Jul 5.

Department of Physiology and Cell Biology, The Ohio State University, Columbus, OH, United States; Davis Heart and Lung Research Institute, The Ohio State University, Columbus, OH, United States; Department of Internal Medicine, The Ohio State University, Columbus, OH, United States. Electronic address:

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http://dx.doi.org/10.1016/j.yjmcc.2018.07.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6103886PMC
August 2018

Increased cross-bridge recruitment contributes to transient increase in force generation beyond maximal capacity in human myocardium.

J Mol Cell Cardiol 2018 01 12;114:116-123. Epub 2017 Nov 12.

Department of Physiology and Cell Biology, The Ohio State University Wexner Medical Center, USA; Dorothy M. Davis Heart and Lung Research Institute, The Ohio State University Wexner Medical Center, USA; Department of Internal Medicine, The Ohio State University Wexner Medical Center, USA. Electronic address:

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http://dx.doi.org/10.1016/j.yjmcc.2017.11.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5801127PMC
January 2018

In Vivo Genome Editing Restores Dystrophin Expression and Cardiac Function in Dystrophic Mice.

Circ Res 2017 Sep 8;121(8):923-929. Epub 2017 Aug 8.

From the Department of Surgery, Davis Heart and Lung Research Institute, Biomedical Sciences Graduate Program, Biophysics Graduate Program (M.E.R., L.X., Y.G., T.M.A.A., J.M., R.H.) and Department of Physiology and Cell Biology, Davis Heart and Lung Research Institute (B.D.C., P.J.M., P.M.L.J.), The Ohio State University Wexner Medical Center, Columbus; Genomics Shared Resource, The Ohio State University Comprehensive Cancer Center, Columbus (S.C.W., D.E.S.); and Department of Cancer Biology and Genetics (K.A., D.E.S.) and Human Cancer Genetics Program, and Department of Biomedical Informatics (adjunct) (D.E.S.), The Ohio State University, Columbus.

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http://dx.doi.org/10.1161/CIRCRESAHA.117.310996DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5623072PMC
September 2017

Altered protein levels in the isolated extracellular matrix of failing human hearts with dilated cardiomyopathy.

Cardiovasc Pathol 2017 Jan - Feb;26:12-20. Epub 2016 Oct 15.

The University of New Mexico College of Pharmacy, Department of Pharmaceutical Sciences, MSC09 5360, 1 University of New Mexico, Albuquerque, NM 87131, USA. Electronic address:

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http://dx.doi.org/10.1016/j.carpath.2016.10.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5494967PMC
January 2017

Effects of zacopride, a moderate I channel agonist, on triggered arrhythmia and contractility in human ventricular myocardium.

Pharmacol Res 2017 01 30;115:309-318. Epub 2016 Nov 30.

Department of Physiology and Cell Biology, College of Medicine, The Ohio State University, USA; Dorothy M. Davis Heart & Lung Research Institute, The Ohio State University, Columbus, OH, USA. Electronic address:

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http://dx.doi.org/10.1016/j.phrs.2016.11.033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5234043PMC
January 2017

Insights into length-dependent regulation of cardiac cross-bridge cycling kinetics in human myocardium.

Arch Biochem Biophys 2016 07 18;601:48-55. Epub 2016 Feb 18.

Department of Physiology and Cell Biology, The Ohio State University Wexner Medical Center, USA; Dorothy M. Davis Heart and Lung Research Institute, The Ohio State University Wexner Medical Center, USA; Department of Internal Medicine, The Ohio State University Wexner Medical Center, USA. Electronic address:

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http://dx.doi.org/10.1016/j.abb.2016.02.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4899103PMC
July 2016

Effect of exercise training and myocardial infarction on force development and contractile kinetics in isolated canine myocardium.

J Appl Physiol (1985) 2016 Apr 28;120(8):817-24. Epub 2016 Jan 28.

Department of Physiology and Cell Biology, The Ohio State University, Columbus, Ohio; and Davis Heart and Lung Research Institute, The Ohio State University, Columbus, Ohio

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http://dx.doi.org/10.1152/japplphysiol.00775.2015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4835907PMC
April 2016

The Frank-Starling mechanism involves deceleration of cross-bridge kinetics and is preserved in failing human right ventricular myocardium.

Am J Physiol Heart Circ Physiol 2015 Dec 9;309(12):H2077-86. Epub 2015 Oct 9.

Department of Physiology and Cell Biology, The Ohio State University Wexner Medical Center, Columbus, Ohio; Dorothy M. Davis Heart and Lung Research Institute, The Ohio State University Wexner Medical Center, Columbus, Ohio; Department of Internal Medicine, The Ohio State University Wexner Medical Center, Columbus, Ohio; and

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http://ajpheart.physiology.org/content/ajpheart/309/12/H2077
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http://ajpheart.physiology.org/lookup/doi/10.1152/ajpheart.0
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http://dx.doi.org/10.1152/ajpheart.00685.2015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4698421PMC
December 2015

Variations in measurement of sexual activity based on EHR definitions.

Pediatrics 2014 May 14;133(5):e1305-12. Epub 2014 Apr 14.

Department of Pediatrics, The Ohio State University College of Medicine, Columbus, Ohio; Innovation in Pediatric Practice, The Research Institute at Nationwide Children's Hospital, Columbus, Ohio; and.

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http://dx.doi.org/10.1542/peds.2013-3232DOI Listing
May 2014

IKKα and alternative NF-κB regulate PGC-1β to promote oxidative muscle metabolism.

J Cell Biol 2012 Feb;196(4):497-511

Department of Molecular Virology, Immunology, and Medical Genetics, Human Cancer Genetics Program, The Ohio State University, Columbus, OH 43210, USA.

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http://www.jcb.org/lookup/doi/10.1083/jcb.201108118
Publisher Site
http://dx.doi.org/10.1083/jcb.201108118DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3284000PMC
February 2012

Early treatment with lisinopril and spironolactone preserves cardiac and skeletal muscle in Duchenne muscular dystrophy mice.

Circulation 2011 Aug 18;124(5):582-8. Epub 2011 Jul 18.

Davis Heart and Lung Research Institute, Division of Cardiovascular Medicine, Department of Molecular and Cellular Biochemistry, The Ohio State University, Columbus, OH, USA.

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http://dx.doi.org/10.1161/CIRCULATIONAHA.111.031716DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3150227PMC
August 2011

A genetic model of amyotrophic lateral sclerosis in zebrafish displays phenotypic hallmarks of motoneuron disease.

Dis Model Mech 2010 Sep-Oct;3(9-10):652-62. Epub 2010 May 26.

Center for Molecular Neurobiology and Department of Neuroscience, The Ohio State University, Columbus, OH 43210, USA.

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http://dx.doi.org/10.1242/dmm.005538DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2931540PMC
December 2010