Benjamin C Y Wong

Benjamin C Y Wong

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Benjamin C Y Wong

Publications by authors named "Benjamin C Y Wong"

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Gastric cancer chemoprevention: the current evidence.

Gastroenterol Clin North Am 2013 Jun 13;42(2):299-316. Epub 2013 Mar 13.

Department of Medicine, University of Hong Kong, Hong Kong.

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http://dx.doi.org/10.1016/j.gtc.2013.02.001DOI Listing
June 2013

Treatment of functional dyspepsia with sertraline: a double-blind randomized placebo-controlled pilot study.

World J Gastroenterol 2012 Nov;18(42):6127-33

Department of Medicine, University of Hong Kong, Queen Marry Hospital, Hong Kong, China.

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http://dx.doi.org/10.3748/wjg.v18.i42.6127DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3496890PMC
November 2012

Current understanding of the role of PPARγ in gastrointestinal cancers.

PPAR Res 2009 26;2009:816957. Epub 2009 Oct 26.

Department of Medicine; Centre Cancer Research, The University of Hong Kong, Pok Fu Lam Road, Hong Kong.

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http://dx.doi.org/10.1155/2009/816957DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2770108PMC
September 2012

XIAP-associated factor 1 (XAF1), a novel target of p53, enhances p53-mediated apoptosis via post-translational modification.

Mol Carcinog 2012 May 15;51(5):422-32. Epub 2011 Jun 15.

Department of Gastroenterology & Hepatology, The Third Affiliated Hospital of Guangzhou Medical College, Guangzhou, PR China.

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http://dx.doi.org/10.1002/mc.20807DOI Listing
May 2012

Role of PCDH10 and its hypermethylation in human gastric cancer.

Biochim Biophys Acta 2012 Feb 20;1823(2):298-305. Epub 2011 Dec 20.

Shenzhen Second People's Hospital, First Affiliated Hospital of Shenzhen University, 3002 Shungang West Road, Futian District, Shenzhen 518036, Guangdong Province, PR China.

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http://linkinghub.elsevier.com/retrieve/pii/S016748891100313
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http://dx.doi.org/10.1016/j.bbamcr.2011.11.011DOI Listing
February 2012

A possible role of cIAP2 in Helicobacter pylori-associated gastric cancer.

Cancer Lett 2011 Dec 12;313(2):192-200. Epub 2011 Sep 12.

Shenzhen Second People's Hospital, The First Affiliated Hospital of Shenzhen University, 3002 Shungang West Road, Futian District, Shenzhen 518035, Guangdong Province, China.

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http://dx.doi.org/10.1016/j.canlet.2011.09.007DOI Listing
December 2011

Treatment of non-erosive reflux disease with a proton pump inhibitor in Chinese patients: a randomized controlled trial.

J Gastroenterol 2011 Jul 3;46(7):906-12. Epub 2011 May 3.

Department of Medicine, Queen Mary Hospital, University of Hong Kong, Hong Kong, China.

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http://dx.doi.org/10.1007/s00535-011-0402-1DOI Listing
July 2011

XIAP-associated factor 1 interacts with and attenuates the trans-activity of four and a Half LIM protein 2.

Mol Carcinog 2011 Mar 23;50(3):199-207. Epub 2010 Nov 23.

Guangdong Provincial Key Laboratory of Gastroenterology, Department of Gastroenterology, Nanfang Hospital, Southern Medical University, Guangzhou, China.

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http://doi.wiley.com/10.1002/mc.20705
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http://dx.doi.org/10.1002/mc.20705DOI Listing
March 2011

Four and a half LIM protein 2 (FHL2) negatively regulates the transcription of E-cadherin through interaction with Snail1.

Eur J Cancer 2011 Jan;47(1):121-30

Guangdong Provincial Key Laboratory of Gastroenterology, Department of Gastroenterology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.

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http://dx.doi.org/10.1016/j.ejca.2010.07.045DOI Listing
January 2011

Helicobacter pylori and gastritis: Untangling a complex relationship 27 years on.

J Gastroenterol Hepatol 2011 Jan;26 Suppl 1:42-5

Department of Medicine, University of Hong Kong, China.

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http://dx.doi.org/10.1111/j.1440-1746.2010.06593.xDOI Listing
January 2011

Rabeprazole is effective in treating laryngopharyngeal reflux in a randomized placebo-controlled trial.

Clin Gastroenterol Hepatol 2010 Sep 18;8(9):770-6. Epub 2010 Mar 18.

Department of Surgery, University of Hong Kong, Hong Kong, China.

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http://linkinghub.elsevier.com/retrieve/pii/S154235651000254
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http://dx.doi.org/10.1016/j.cgh.2010.03.009DOI Listing
September 2010

Promoter hypermethylation and histone hypoacetylation contribute to pancreatic-duodenal homeobox 1 silencing in gastric cancer.

Carcinogenesis 2010 Sep 9;31(9):1552-60. Epub 2010 Jul 9.

Department of Gastroenterology and Hepatology, Guangdong General Hospital, Guangzhou 510080, China.

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http://dx.doi.org/10.1093/carcin/bgq140DOI Listing
September 2010

Proton pump inhibitor and clopidogrel interaction: the case for watchful waiting.

J Gastroenterol Hepatol 2010 Aug;25(8):1342-7

Department of Medicine, University of Hong Kong, Queen Mary Hospital, Hong Kong, China.

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http://dx.doi.org/10.1111/j.1440-1746.2010.06366.xDOI Listing
August 2010

Four-and-a-half LIM protein 2 promotes invasive potential and epithelial-mesenchymal transition in colon cancer.

Carcinogenesis 2010 Jul 11;31(7):1220-9. Epub 2010 May 11.

Guangdong Provincial key Laboratory of Gastroenterology, Department of Gastroenterology, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.

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http://dx.doi.org/10.1093/carcin/bgq094DOI Listing
July 2010

Functional characterisation of cell cycle-related kinase (CCRK) in colorectal cancer carcinogenesis.

Eur J Cancer 2010 Jun 11;46(9):1752-61. Epub 2010 May 11.

Integrative Chemical Biology Laboratory, Department of Chemistry, The University of Hong Kong, China.

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http://dx.doi.org/10.1016/j.ejca.2010.04.007DOI Listing
June 2010

Trend of colorectal cancer in Hong Kong: 1983-2006.

J Gastroenterol Hepatol 2010 May 14;25(5):923-7. Epub 2010 Jan 14.

HK Health Enhancement Research Centre, The University of Hong Kong, Hong Kong.

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http://dx.doi.org/10.1111/j.1440-1746.2009.06130.xDOI Listing
May 2010

C-reactive protein promotes cardiac fibrosis and inflammation in angiotensin II-induced hypertensive cardiac disease.

Hypertension 2010 Apr 15;55(4):953-60. Epub 2010 Feb 15.

Department of Medicine, University of Hong Kong, Hong Kong Special Administrative Region, China.

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http://dx.doi.org/10.1161/HYPERTENSIONAHA.109.140608DOI Listing
April 2010

Chemoprophylaxis in colorectal cancer: current concepts and a practical algorithm for use.

Expert Opin Investig Drugs 2010 Apr;19 Suppl 1:S57-66

University of Hong Kong, Queen Mary Hospital, Center for Cancer Research, Department of Medicine, Hong Kong.

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http://dx.doi.org/10.1517/13543781003714923DOI Listing
April 2010

Role of Notch signaling in colorectal cancer.

Carcinogenesis 2009 Dec;30(12):1979-86

Department of Medicine and Centre for Cancer Research, The University of Hong Kong, Queen Mary Hospital, Hong Kong.

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https://academic.oup.com/carcin/article-lookup/doi/10.1093/c
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http://dx.doi.org/10.1093/carcin/bgp236DOI Listing
December 2009

Epidemiology of colorectal cancer in Asia.

J Gastroenterol Hepatol 2009 Dec;24(12):1810-6

Medicare Endoscopy Centre, The University of Hong Kong, Hong Kong.

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http://dx.doi.org/10.1111/j.1440-1746.2009.06138.xDOI Listing
December 2009

Quality of life in patients with laryngopharyngeal reflux.

Digestion 2009 22;79(1):52-7. Epub 2008 Oct 22.

Department of Medicine, University of Hong Kong, SAR, China.

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http://dx.doi.org/10.1159/000205267DOI Listing
July 2009

Normal values of 24-hour combined esophageal multichannel intraluminal impedance and pH monitoring in the Chinese population.

Digestion 2009 18;79(2):109-14. Epub 2009 Mar 18.

Department of Gastroenterology, First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, China.

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https://www.karger.com/Article/FullText/209220
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http://dx.doi.org/10.1159/000209220DOI Listing
July 2009

Targeting apoptosis as an approach for gastrointestinal cancer therapy.

Drug Resist Updat 2009 Jun 10;12(3):55-64. Epub 2009 Mar 10.

Department of Medicine and Centre for Cancer Research, The University of Hong Kong, Hong Kong.

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http://dx.doi.org/10.1016/j.drup.2009.02.002DOI Listing
June 2009

Reflux profile of Chinese gastroesophageal reflux disease patients with combined multichannel intraluminal impedance-pH monitoring.

J Gastroenterol Hepatol 2009 Jun;24(6):1113-8

Department of Gastroenterology, First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.

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http://dx.doi.org/10.1111/j.1440-1746.2009.05861.xDOI Listing
June 2009

Alterations of gastric homeoprotein expression in Helicobacter pylori infection, incisural antralisation, and intestinal metaplasia.

Dig Dis Sci 2009 May 27;54(5):996-1002. Epub 2008 Aug 27.

Department of Gastroenterology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.

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http://link.springer.com/10.1007/s10620-008-0459-8
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http://dx.doi.org/10.1007/s10620-008-0459-8DOI Listing
May 2009

Gastroesophageal reflux disease is associated with poor asthma control, quality of life, and psychological status in Chinese asthma patients.

Chest 2009 May 31;135(5):1181-1185. Epub 2008 Dec 31.

Department of Medicine, University of Hong Kong, Hong Kong, People's Republic of China. Electronic address:

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http://dx.doi.org/10.1378/chest.08-1702DOI Listing
May 2009

Assessing the risks and benefits of treating Helicobacter pylori infection.

Therap Adv Gastroenterol 2009 May;2(3):141-7

Department of Medicine, University of Hong Kong, Queen Mary Hospital, Hong Kong.

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http://dx.doi.org/10.1177/1756283X08100279DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3002520PMC
May 2009

Prevalence and time trend of intestinal metaplasia in Hong Kong.

J Gastroenterol Hepatol 2009 May;24(5):896-9

Department of Medicine, The University of Hong Kong, Hong Kong.

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http://dx.doi.org/10.1111/j.1440-1746.2009.05799.xDOI Listing
May 2009

Factors affecting physicians' practices related to Helicobacter pylori infection: effect of experience and mode of practice.

Digestion 2008 24;78(2-3):77-81. Epub 2008 Oct 24.

Hong Kong Health Enhancement Research Centre, Hong Kong, SAR, China.

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http://dx.doi.org/10.1159/000165353DOI Listing
April 2009

Gene expression profile in colon cancer cells with respect to XIAP expression status.

Int J Colorectal Dis 2009 Mar 13;24(3):245-60. Epub 2008 Aug 13.

Department of Medicine, The University of Hong Kong, Queen Mary Hospital, Pokfulam Road, Hong Kong, China.

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http://link.springer.com/content/pdf/10.1007/s00384-008-0566
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http://link.springer.com/10.1007/s00384-008-0566-1
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http://dx.doi.org/10.1007/s00384-008-0566-1DOI Listing
March 2009

Oncogene functions of FHL2 are independent from NF-kappaBIalpha in gastrointestinal cancer.

Pathol Oncol Res 2009 Mar 28;15(1):31-6. Epub 2008 Aug 28.

Department of Medicine, The University of Hong Kong, Hong Kong, China.

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http://dx.doi.org/10.1007/s12253-008-9085-1DOI Listing
March 2009

c-Jun N-terminal kinase (JNK1) upregulates XIAP-associated factor 1 (XAF1) through interferon regulatory factor 1 (IRF-1) in gastrointestinal cancer.

Carcinogenesis 2009 Feb 4;30(2):222-9. Epub 2008 Dec 4.

Department of Digestive Medicine, Nanfang Hospital, Southern Medical University, Guangzhou, China.

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http://dx.doi.org/10.1093/carcin/bgn271DOI Listing
February 2009

Non-cardiac chest pain in Asia: time for a consensus.

J Gastroenterol Hepatol 2009 Feb;24(2):178-9

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http://dx.doi.org/10.1111/j.1440-1746.2008.05754.xDOI Listing
February 2009

Serological proteomics of gastritis: degradation of apolipoprotein A-I and alpha1-antitrypsin is a common response to inflammation irrespective of Helicobacter pylori infection.

Dig Dis Sci 2008 Dec 2;53(12):3112-8. Epub 2008 Jul 2.

Institute of Life and Health Engineering, Jinan University, Guangzhou, 510632, China.

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http://link.springer.com/10.1007/s10620-008-0269-z
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http://dx.doi.org/10.1007/s10620-008-0269-zDOI Listing
December 2008

Upper gastrointestinal bleeding in patients with aspirin and clopidogrel co-therapy.

Digestion 2008 25;77(3-4):173-7. Epub 2008 Jun 25.

Department of Medicine and Surgery, Ruttonjee Hospital, Hong Kong, SAR, China.

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http://dx.doi.org/10.1159/000141264DOI Listing
November 2008

Early upregulation of cyclooxygenase-2 in human papillomavirus type 16 and telomerase-induced immortalization of human esophageal epithelial cells.

J Gastroenterol Hepatol 2008 Oct 20;23(10):1613-20. Epub 2008 Aug 20.

Department of Gastroenterology, The First Affiliated Hospital of Fujian Medical University, Fujian, China.

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http://dx.doi.org/10.1111/j.1440-1746.2008.05509.xDOI Listing
October 2008

Loss of XIAP sensitizes colon cancer cells to PPARgamma independent antitumor effects of troglitazone and 15-PGJ2.

Cancer Lett 2008 Sep 13;268(2):260-71. Epub 2008 May 13.

Department of Medicine, University of Hong Kong, Queen Mary Hospital, Hong Kong.

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http://dx.doi.org/10.1016/j.canlet.2008.04.003DOI Listing
September 2008

The four-and-a-half-LIM protein 2 (FHL2) is overexpressed in gliomas and associated with oncogenic activities.

Glia 2008 Sep;56(12):1328-38

Department of Chemistry, Open laboratory of Chemical Biology, University of Hong Kong, Hong Kong, People's Republic of China.

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http://dx.doi.org/10.1002/glia.20701DOI Listing
September 2008

XIAP-associated factor 1 (XAF1) suppresses angiogenesis in mouse endothelial cells.

Tumour Biol 2008 11;29(2):122-9. Epub 2008 Jun 11.

Department of Medicine, University of Hong Kong, Hong Kong, China.

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http://dx.doi.org/10.1159/000137831DOI Listing
August 2008

Gastro-oesophageal reflux disease in Asia : birth of a 'new' disease?

Drugs 2008 ;68(4):399-406

Department of Medicine, University of Hong Kong, Hong Kong.

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http://dx.doi.org/10.2165/00003495-200868040-00001DOI Listing
July 2008

Pancreatic duodenal homeobox-1 (PDX1) functions as a tumor suppressor in gastric cancer.

Carcinogenesis 2008 Jul 13;29(7):1327-33. Epub 2008 May 13.

Division of Gastroenterology and Hepatology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, China.

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http://dx.doi.org/10.1093/carcin/bgn112DOI Listing
July 2008

Loss of XIAP sensitizes rosiglitazone-induced growth inhibition of colon cancer in vivo.

Int J Cancer 2008 Jun;122(12):2858-63

Department of Gastroenterology, Peking University First Hospital, Beijing, China.

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http://dx.doi.org/10.1002/ijc.23443DOI Listing
June 2008

Interactions between XIAP associated factor 1 and a nuclear co-activator, CBP, in colon cancer cells.

Digestion 2008 21;77(2):79-86. Epub 2008 Mar 21.

Division of Gastroenterology, Ruijin Hospital, Department of Medicine, Shanghai Jiaotong University, Shanghai, PR China.

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http://dx.doi.org/10.1159/000121441DOI Listing
June 2008

Gastrointestinal bleeding in patients receiving a combination of aspirin, clopidogrel, and enoxaparin in acute coronary syndrome.

Am J Gastroenterol 2008 Apr 2;103(4):865-71. Epub 2008 Jan 2.

Department of Medicine, Ruttonjee Hospital, Hong Kong, China.

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http://dx.doi.org/10.1111/j.1572-0241.2007.01715.xDOI Listing
April 2008

Treatment of Helicobacter pylori and prevention of gastric cancer.

J Dig Dis 2008 Feb;9(1):8-13

Department of Medicine, University of Hong Kong, Hong Kong.

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http://dx.doi.org/10.1111/j.1443-9573.2007.00315.xDOI Listing
February 2008

Decreasing trend of esophageal adenocarcinoma in Hong Kong.

Cancer Epidemiol Biomarkers Prev 2007 Dec;16(12):2637-40

Department of Medicine, University of Hong Kong, Hong Kong.

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http://dx.doi.org/10.1158/1055-9965.EPI-07-0421DOI Listing
December 2007

Noncardiac chest pain--an Asia-Pacific survey on the views of primary care physicians.

Dig Dis Sci 2007 Nov 10;52(11):3043-8. Epub 2007 Apr 10.

Department of Medicine, University of Hong Kong, Queen Mary Hospital, Hong Kong.

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http://dx.doi.org/10.1007/s10620-007-9764-xDOI Listing
November 2007

Do serrated adenomas have higher malignant potential than traditional adenomas?

J Gastroenterol Hepatol 2007 Nov;22(11):1701-3

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http://dx.doi.org/10.1111/j.1440-1746.2007.05204.xDOI Listing
November 2007

American College of Gastroenterology guideline on the management of Helicobacter pylori infection.

Am J Gastroenterol 2007 Aug 29;102(8):1808-25. Epub 2007 Jun 29.

University of Michigan Medical Center, Ann Arbor, Michigan 48109, USA.

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http://dx.doi.org/10.1111/j.1572-0241.2007.01393.xDOI Listing
August 2007

Cell cycle-related kinase: a novel candidate oncogene in human glioblastoma.

J Natl Cancer Inst 2007 Jun 12;99(12):936-48. Epub 2007 Jun 12.

Department of Chemistry, Open Laboratory of Chemical Biology, The University of Hong Kong, Pokfulam, Hong Kong, China.

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http://dx.doi.org/10.1093/jnci/djm011DOI Listing
June 2007

XAF1 mediates apoptosis through an extracellular signal-regulated kinase pathway in colon cancer.

Cancer 2007 May;109(10):1996-2003

Department of Gastroenterology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

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http://dx.doi.org/10.1002/cncr.22624DOI Listing
May 2007

An inverse correlation between Interleukin-6 and select gene promoter methylation in patients with gastric cancer.

Digestion 2006 30;74(2):85-90. Epub 2006 Nov 30.

Department of Medicine, University of Hong Kong, Hong Kong, SAR, China.

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http://dx.doi.org/10.1159/000097623DOI Listing
March 2007

Suppression of FHL2 expression induces cell differentiation and inhibits gastric and colon carcinogenesis.

Gastroenterology 2007 Mar 3;132(3):1066-76. Epub 2006 Dec 3.

Institute for Digestive Medicine, Nanfang Hospital, Southern Medical University, Guangzhou, People's Republic of China.

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http://dx.doi.org/10.1053/j.gastro.2006.12.004DOI Listing
March 2007

Effects of proton-pump inhibitors on functional dyspepsia: a meta-analysis of randomized placebo-controlled trials.

Clin Gastroenterol Hepatol 2007 Feb 14;5(2):178-85; quiz 140. Epub 2006 Dec 14.

Department of Gastroenterology, Peking University First Hospital, Beijing, China.

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http://dx.doi.org/10.1016/j.cgh.2006.09.012DOI Listing
February 2007

Influence of positive family history on clinical characteristics of functional constipation.

Clin Gastroenterol Hepatol 2007 Feb 9;5(2):197-200. Epub 2007 Jan 9.

Division of Gastroenterology and Hepatology, Department of Medicine, University of Hong Kong, Queen Mary Hospital, Hong Kong.

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http://dx.doi.org/10.1016/j.cgh.2006.10.009DOI Listing
February 2007

Familial aggregation in constipated subjects in a tertiary referral center.

Am J Gastroenterol 2007 Jan 13;102(1):149-52. Epub 2006 Oct 13.

Department of Medicine, Univresity of Hong Kong, Queen Mary Hospital, Hong Kong.

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http://www.nature.com/doifinder/10.1111/j.1572-0241.2006.008
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http://dx.doi.org/10.1111/j.1572-0241.2006.00886.xDOI Listing
January 2007

Helicobacter pylori eradication for gastric cancer prevention.

J Gastroenterol 2007 Jan;42 Suppl 17:10-5

Department of Medicine, University of Hong Kong, Queen Mary Hospital, Pokfulam Road, Hong Kong, China.

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http://link.springer.com/10.1007/s00535-006-1939-2
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http://dx.doi.org/10.1007/s00535-006-1939-2DOI Listing
January 2007

Correlation between the single-site CpG methylation and expression silencing of the XAF1 gene in human gastric and colon cancers.

Gastroenterology 2006 Dec 1;131(6):1835-43. Epub 2006 Oct 1.

Department of Gastroenterology, Rui-jin Hospital, Shanghai Jiao Tong University, Shanghai, China.

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http://dx.doi.org/10.1053/j.gastro.2006.09.050DOI Listing
December 2006

Systematic review on epidemiology of gastroesophageal reflux disease in Asia.

Clin Gastroenterol Hepatol 2006 Apr;4(4):398-407

Department of Medicine, University of Hong Kong, Queen Mary Hospital, Pokfulam, Hong Kong.

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http://linkinghub.elsevier.com/retrieve/pii/S154235650501047
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http://dx.doi.org/10.1016/j.cgh.2005.10.011DOI Listing
April 2006

All-trans retinoic acid induces XAF1 expression through an interferon regulatory factor-1 element in colon cancer.

Gastroenterology 2006 Mar;130(3):747-58

Institute for Digestive Medicine, Nanfang Hospital, Southern Medical University, Guangzhou, People's Republic of China.

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http://dx.doi.org/10.1053/j.gastro.2005.12.017DOI Listing
March 2006

HSF1 down-regulates XAF1 through transcriptional regulation.

J Biol Chem 2006 Feb 21;281(5):2451-9. Epub 2005 Nov 21.

Institute for Digestive Medicine, Nanfang Hospital, Southern Medical University, Guangzhou.

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http://www.jbc.org/content/281/5/2451.full.pdf
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http://www.jbc.org/cgi/doi/10.1074/jbc.M505890200
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http://dx.doi.org/10.1074/jbc.M505890200DOI Listing
February 2006

Diagnosis of Barrett's esophagus in the Asian population.

J Gastroenterol Hepatol 2005 Mar;20(3):495

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http://dx.doi.org/10.1111/j.1440-1746.2005.03777.xDOI Listing
March 2005

Protein kinase C delta is not activated by caspase-3 and its inhibition is sufficient to induce apoptosis in the colon cancer line, COLO 205.

Cell Signal 2005 Feb;17(2):253-62

Division of Medical Sciences, The Medical School, University of Birmingham, B15 2TT, UK.

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http://dx.doi.org/10.1016/j.cellsig.2004.07.005DOI Listing
February 2005

Evolutionary dynamics of insertion sequences in Helicobacter pylori.

J Bacteriol 2004 Nov;186(22):7508-20

Department of Molecular Microbiology, Washington University School of Medicine, Saint Louis, Missouri, USA.

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http://dx.doi.org/10.1128/JB.186.22.7508-7520.2004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC524885PMC
November 2004