Publications by authors named "Benjamin Busch"

20Publications

The HopQ-CEACAM Interaction Controls CagA Translocation, Phosphorylation, and Phagocytosis of in Neutrophils.

mBio 2020 02 4;11(1). Epub 2020 Feb 4.

Chair of Medical Microbiology and Hospital Epidemiology, Max von Pettenkofer Institute, Faculty of Medicine, LMU Munich, Munich, Germany

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http://dx.doi.org/10.1128/mBio.03256-19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7002351PMC
February 2020

Integrin but not CEACAM receptors are dispensable for Helicobacter pylori CagA translocation.

PLoS Pathog 2018 10 26;14(10):e1007359. Epub 2018 Oct 26.

Chair of Medical Microbiology and Hospital Epidemiology, Max von Pettenkofer Institute, Faculty of Medicine, LMU Munich, Germany.

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http://dx.plos.org/10.1371/journal.ppat.1007359
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http://dx.doi.org/10.1371/journal.ppat.1007359DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6231679PMC
October 2018

Helicobacter pylori exploits human CEACAMs via HopQ for adherence and translocation of CagA.

Nat Microbiol 2016 10 17;2:16188. Epub 2016 Oct 17.

Max von Pettenkofer-Institut für Hygiene und Medizinische Mikrobiologie, Ludwig-Maximilians-Universität, Pettenkoferstraße 9a, München D-80336, Germany.

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http://dx.doi.org/10.1038/nmicrobiol.2016.188DOI Listing
October 2016

Characterization of Helicobacter pylori VacA-containing vacuoles (VCVs), VacA intracellular trafficking and interference with calcium signalling in T lymphocytes.

Cell Microbiol 2015 Dec 16;17(12):1811-32. Epub 2015 Jul 16.

Max von Pettenkofer-Institut für Hygiene und Medizinische Mikrobiologie, Ludwig-Maximilians-Universität, München, Germany.

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http://dx.doi.org/10.1111/cmi.12474DOI Listing
December 2015

Helicobacter pylori interferes with leukocyte migration via the outer membrane protein HopQ and via CagA translocation.

Int J Med Microbiol 2015 May 14;305(3):355-64. Epub 2015 Feb 14.

Max von Pettenkofer-Institut für Hygiene und Medizinische Mikrobiologie, Ludwig-Maximilians-Universität, München, Germany; German Center for Infection Research, Partner Site München, München, Germany.

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http://dx.doi.org/10.1016/j.ijmm.2015.02.003DOI Listing
May 2015

Freedom and constraint in engineered noncolinear polyketide assembly lines.

Chem Biol 2015 Feb 5;22(2):229-40. Epub 2015 Feb 5.

Department of Biomolecular Chemistry, Leibniz Institute for Natural Product Research and Infection Biology (HKI), Beutenbergstr. 11a, 07745 Jena, Germany; Natural Product Chemistry, Friedrich Schiller University, Jena, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.chembiol.2014.12.014DOI Listing
February 2015

Vinylogous chain branching catalysed by a dedicated polyketide synthase module.

Nature 2013 Oct 18;502(7469):124-8. Epub 2013 Sep 18.

Department of Biomolecular Chemistry, Leibniz Institute for Natural Product Research and Infection Biology (HKI), Jena 07745, Germany.

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http://dx.doi.org/10.1038/nature12588DOI Listing
October 2013

Multifactorial control of iteration events in a modular polyketide assembly line.

Angew Chem Int Ed Engl 2013 May 18;52(20):5285-9. Epub 2013 Apr 18.

Leibniz-Institut für Naturstoff-Forschung und Infektionsbiologie - Hans-Knöll-Institut (HKI), Abteilung für Biomolekulare Chemie, Beutenbergstrasse 11a, 07745 Jena, Germany.

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http://dx.doi.org/10.1002/anie.201301322DOI Listing
May 2013

Pyran formation by an atypical CYP-mediated four-electron oxygenation-cyclization cascade in an engineered aureothin pathway.

Chembiochem 2012 Oct 7;13(15):2196-9. Epub 2012 Sep 7.

Dept. Biomolecular Chemistry, Leibniz Institute for Natural Product Research and Infection Biology, HKI, Beutenbergstrasse 11a, 07745 Jena, Germany.

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http://dx.doi.org/10.1002/cbic.201200406DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3517090PMC
October 2012

Symbiotic cooperation in the biosynthesis of a phytotoxin.

Angew Chem Int Ed Engl 2012 Sep 22;51(38):9615-8. Epub 2012 Aug 22.

Biomolecular Chemistry, Leibniz Institute for Natural Product Research and Infection Biology, HKI, Beutenbergstr. 11a, 07745 Jena, Germany.

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http://dx.doi.org/10.1002/anie.201204540DOI Listing
September 2012

Interchenar retrotransfer of aureothin intermediates in an iterative polyketide synthase module.

J Am Chem Soc 2012 Aug 23;134(30):12382-5. Epub 2012 Jul 23.

Leibniz Institute for Natural Product Research and Infection Biology, HKI, Jena, Germany.

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http://dx.doi.org/10.1021/ja304454rDOI Listing
August 2012

Structural characterization of two lipopolysaccharide O-antigens produced by the endofungal bacterium Burkholderia sp. HKI-402 (B4).

Carbohydr Res 2012 Jan 4;347(1):95-8. Epub 2011 Nov 4.

Dipartimento di Chimica Organica e Biochimica, Università di Napoli Federico II, via Cintia 4, 80126 Napoli, Italy.

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http://dx.doi.org/10.1016/j.carres.2011.10.038DOI Listing
January 2012

Exploiting enzymatic promiscuity to engineer a focused library of highly selective antifungal and antiproliferative aureothin analogues.

J Am Chem Soc 2010 Aug;132(30):10407-13

Leibniz Institute for Natural Product Research and Infection Biology, HKI, Dept. of Biomolecular Chemistry, Beutenbergstr. 11a, 07745 Jena, Germany.

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http://dx.doi.org/10.1021/ja102751hDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2925430PMC
August 2010

Functionally distinct modules operate two consecutive alpha,beta-->beta,gamma double-bond shifts in the rhizoxin polyketide assembly line.

Angew Chem Int Ed Engl 2010 Feb;49(8):1460-4

Leibniz-Institut für Naturstoff-Forschung und Infektionsbiologie e.V., Hans-Knöll-Institut, Abteilung Biomolekulare Chemie und Biotechnikum, Beutenbergstrasse 11a, 07745 Jena, Germany.

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http://doi.wiley.com/10.1002/anie.200905467
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http://dx.doi.org/10.1002/anie.200905467DOI Listing
February 2010

Evolution of metabolic diversity in polyketide-derived pyrones: using the non-colinear aureothin assembly line as a model system.

Phytochemistry 2009 Oct-Nov;70(15-16):1833-40. Epub 2009 Aug 3.

Leibniz Institute for Natural Product Research and Infection Biology, HKI, Department of Biomolecular Chemistry, Jena, Germany.

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http://linkinghub.elsevier.com/retrieve/pii/S003194220900217
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http://dx.doi.org/10.1016/j.phytochem.2009.05.022DOI Listing
January 2010

Polyketide-chain branching by an enzymatic Michael addition.

Angew Chem Int Ed Engl 2009 ;48(27):5001-4

Leibniz Institute for Natural Product Research and Infection Biology, HKI, Department of Biomolecular Chemistry and Bio Pilot Plant, Beutenbergstrasse 11a, 07745 Jena, Germany.

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http://dx.doi.org/10.1002/anie.200900277DOI Listing
September 2009