Publications by authors named "Benjamin Bonavida"

100Publications

Vivid Memories of Sercarz's Traineeship and Am Indebted to Him for My Professional Career.

Crit Rev Immunol 2020 ;40(4):347-352

Department of Microbiology, Immunology, & Molecular Genetics, David Geffen School of Medicine, Johnson Comprehensive Cancer Center, University of California at Los Angeles, Los Angeles, CA 90025-1747.

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January 2020

Sensitizing activities of nitric oxide donors for cancer resistance to anticancer therapeutic drugs.

Biochem Pharmacol 2020 06 12;176:113913. Epub 2020 Mar 12.

Department of Microbiology, Immunology, and Molecular Genetics, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, United States. Electronic address:

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June 2020

Nitric Oxide-Mediated Enhancement and Reversal of Resistance of Anticancer Therapies.

Antioxidants (Basel) 2019 Sep 17;8(9). Epub 2019 Sep 17.

Department of Microbiology, Immunology and Molecular Genetics, David Geffen School of Medicine, University of California Los Angeles, CA 90095, USA.

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September 2019

YY1 regulates cancer cell immune resistance by modulating PD-L1 expression.

Drug Resist Updat 2019 03 9;43:10-28. Epub 2019 Apr 9.

Department of Microbiology, Immunology and Molecular Genetics, David Geffen School of Medicine, University of California, Los Angeles, CA, 90095, United States. Electronic address:

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March 2019

Involvement of Yin Yang 1 (YY1) Expression in T-Cell Subsets Differentiation and Their Functions: Implications in T Cell-Mediated Diseases.

Crit Rev Immunol 2019 ;39(6):491-510

Department of Microbiology, Immunology, & Molecular Genetics, David Geffen School of Medicine, Johnson Comprehensive Cancer Center, University of California at Los Angeles, Los Angeles, CA 90025-1747.

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September 2020

Identifying Crosstalk between Raf Kinase Inhibitor Protein and Systemic Lupus Erythematosus.

Crit Rev Immunol 2019 ;39(6):423-437

Department of Microbiology, Immunology, & Molecular Genetics, David Geffen School of Medicine, Johnson Comprehensive Cancer Center, University of California at Los Angeles, Los Angeles, CA 90025-1747.

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September 2020

Linking Autophagy and the Dysregulated NFκB/ SNAIL/YY1/RKIP/PTEN Loop in Cancer: Therapeutic Implications.

Crit Rev Oncog 2018 ;23(5-6):307-320

Department of Microbiology, Immunology, & Molecular Genetics, David Geffen School of Medicine, Johnson Comprehensive Cancer Center, University of California at Los Angeles, Los Angeles, CA 90025-1747.

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August 2019

A New Linkage between the Tumor Suppressor RKIP and Autophagy: Targeted Therapeutics.

Crit Rev Oncog 2018 ;23(5-6):281-305

Department of Microbiology, Immunology, & Molecular Genetics, David Geffen School of Medicine, Johnson Comprehensive Cancer Center, University of California at Los Angeles, Los Angeles, CA 90025-1747.

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August 2019

RKIP: A Key Regulator in Tumor Metastasis Initiation and Resistance to Apoptosis: Therapeutic Targeting and Impact.

Cancers (Basel) 2018 Aug 24;10(9). Epub 2018 Aug 24.

Division of Surgical Oncology, School of Medicine, University of Crete, Heraklion, Crete 71500, Greece.

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August 2018

Exosomes derived from cancerous and non-cancerous cells regulate the anti-tumor response in the tumor microenvironment.

Genes Cancer 2018 Mar;9(3-4):87-100

Department of Microbiology, Immunology & Molecular Genetics, David Geffen School of Medicine, University of California, Los Angeles, CA, USA.

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March 2018

Overexpression of RKIP and its cross-talk with several regulatory gene products in multiple myeloma.

J Exp Clin Cancer Res 2017 05 5;36(1):62. Epub 2017 May 5.

Department of Microbiology, Immunology, and Molecular Genetics, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, 90095, USA.

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May 2017

Crosstalks between Raf-kinase inhibitor protein and cancer stem cell transcription factors (Oct4, KLF4, Sox2, Nanog).

Tumour Biol 2017 Apr;39(4):1010428317692253

Department of Microbiology, Immunology & Molecular Genetics, David Geffen School of Medicine, Jonsson Comprehensive Cancer Center, University of California, Los Angeles, Los Angeles, CA, USA.

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April 2017

Inverse correlation between the metastasis suppressor RKIP and the metastasis inducer YY1: Contrasting roles in the regulation of chemo/immuno-resistance in cancer.

Drug Resist Updat 2017 01 9;30:28-38. Epub 2017 Jan 9.

Department of Microbiology, Immunology & Molecular Genetics, David Geffen School of Medicine, UCLA, Los Angeles, CA, 90095, United States. Electronic address:

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January 2017

The Forgotten YY2 in Reported YY1 Expression Levels in Human Cancers.

Crit Rev Oncog 2017 ;22(1-2):63-73

Department of Microbiology, Immunology, & Molecular Genetics, David Geffen School of Medicine, Johnson Comprehensive Cancer Center, University of California at Los Angeles, Los Angeles, CA.

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April 2019

Targeting the Overexpressed YY1 in Cancer Inhibits EMT and Metastasis.

Crit Rev Oncog 2017 ;22(1-2):49-61

Department of Microbiology, Immunology, & Molecular Genetics, David Geffen School of Medicine, Johnson Comprehensive Cancer Center, University of California at Los Angeles, Los Angeles, CA.

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April 2019

Therapeutic YY1 Inhibitors in Cancer: ALL in ONE.

Crit Rev Oncog 2017 ;22(1-2):37-47

Department of Microbiology, Immunology, & Molecular Genetics, David Geffen School of Medicine, Johnson Comprehensive Cancer Center, University of California at Los Angeles, Los Angeles, CA.

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April 2019

Yin Yang 1 is associated with cancer stem cell transcription factors (SOX2, OCT4, BMI1) and clinical implication.

J Exp Clin Cancer Res 2016 May 25;35:84. Epub 2016 May 25.

Department of Microbiology, Immunology, and Molecular Genetics, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, 90095, USA.

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May 2016

Correlation between the overexpression of Yin Yang 1 and the expression levels of miRNAs in Burkitt's lymphoma: A computational study.

Oncol Lett 2016 Feb 14;11(2):1021-1025. Epub 2015 Dec 14.

Department of Biomedical and Biotechnological Sciences, Section of General and Clinical Pathology, and Oncology, University of Catania, I-95124 Catania, Italy.

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February 2016

Activation of Natural Killer Cells by Probiotics.

For Immunopathol Dis Therap 2016 ;7(1-2):41-55

Department of Microbiology, Immunology, and Molecular Genetics, David Geffen School of Medicine, Jonsson Comprehensive Cancer Center, University of California, Los Angeles, CA 90095.

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January 2016

Special collection: Nitric oxide in cancer.

Redox Biol 2015 Dec 25;6:505-506. Epub 2015 Sep 25.

Department of Microbiology, Immunology, and Molecular Genetics David Geffen School of Medicine Jonsson Comprehensive Cancer Center University of California, Los Angeles, CA 90095, USA. Electronic address:

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December 2015

Nitric oxide-mediated sensitization of resistant tumor cells to apoptosis by chemo-immunotherapeutics.

Redox Biol 2015 Dec 18;6:486-494. Epub 2015 Aug 18.

NantBioScience, Inc., NantWorks, LLC., California NanoSystems Institute (CnSI) at the University of California, Los Angeles, CA 90095, USA.

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December 2015

Overcoming rituximab drug-resistance by the genetically engineered anti-CD20-hIFN-α fusion protein: Direct cytotoxicity and synergy with chemotherapy.

Int J Oncol 2015 Nov 16;47(5):1735-48. Epub 2015 Sep 16.

Oncology Research Unit, Oncology Hospital Siglo XXI National Medical Center, IMSS, Mexico City 06720, Mexico.

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November 2015

Dual roles of nitric oxide in the regulation of tumor cell response and resistance to photodynamic therapy.

Redox Biol 2015 Dec 31;6:311-317. Epub 2015 Jul 31.

Department of Microbiology, Immunology and Molecular Genetics, University of California Los Angeles, Los Angeles, CA 90095, USA. Electronic address:

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December 2015

The Role Of Nitric Oxide After Repeated Low Dose Photodynamic Treatments In Prostate Carcinoma Cells.

Redox Biol 2015 08 30;5:422-423. Epub 2015 Dec 30.

Department of Medical and Biological Sciences, University of Udine, Italy.

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August 2015

Regulation Of Cell Death Apoptotic Pathways By Nitric Oxide In Cancer: Reversal Of Drug/Immune Resistance.

Redox Biol 2015 08 30;5:415. Epub 2015 Dec 30.

Jonsson Comprehensive Cancer Center, University of California, Los Angeles, USA.

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August 2015

Trop2 and its overexpression in cancers: regulation and clinical/therapeutic implications.

Genes Cancer 2015 Mar;6(3-4):84-105

Department of Microbiology, Immunology and Molecular Genetics, Jonsson Comprehensive Cancer Center and David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, CA, USA.

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March 2015

Repeated sub-optimal photodynamic treatments with pheophorbide a induce an epithelial mesenchymal transition in prostate cancer cells via nitric oxide.

Nitric Oxide 2015 Feb 17;45:43-53. Epub 2015 Feb 17.

Department of Medical and Biological Sciences, School of Medicine, University of Udine, Udine, Italy. Electronic address:

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February 2015

Prognostic significance of YY1 protein expression and mRNA levels by bioinformatics analysis in human cancers: a therapeutic target.

Pharmacol Ther 2015 Jun 23;150:149-68. Epub 2015 Jan 23.

Department of Microbiology, Immunology & Molecular Genetics, David Geffen School of Medicine, Jonsson Comprehensive Cancer Center, University of California at Los Angeles, Los Angeles, CA 90095, United States.

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June 2015

RKIP-mediated chemo-immunosensitization of resistant cancer cells via disruption of the NF-κB/Snail/YY1/RKIP resistance-driver loop.

Crit Rev Oncog 2014 ;19(6):431-45

Department of Microbiology, Immunology and Molecular Genetics, Jonsson Comprehensive Cancer Center, David Geffen School of Medicine, University of California at Los Angeles, USA.

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February 2015

Postulated mechanisms of resistance of B-cell non-Hodgkin lymphoma to rituximab treatment regimens: strategies to overcome resistance.

Semin Oncol 2014 Oct 12;41(5):667-77. Epub 2014 Aug 12.

Department of Microbiology, Immunology and Molecular Genetics, Jonsson Comprehensive Cancer Center, David Geffen School of Medicine, University of California, Los Angeles, CA. Electronic address:

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October 2014

Role of YY1 in the pathogenesis of prostate cancer and correlation with bioinformatic data sets of gene expression.

Genes Cancer 2014 Mar;5(3-4):71-83

Department of Microbiology, Immunology, and Molecular Genetics, David Geffen School of Medicine, Jonsson Comprehensive Cancer Center, University of California at Los Angeles, Los Angeles, California.

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March 2014

Overexpression of Yin Yang 1 in bone marrow-derived human multiple myeloma and its clinical significance.

Int J Oncol 2014 Sep 20;45(3):1184-92. Epub 2014 Jun 20.

Department of Microbiology, Immunology and Molecular Genetics, Jonsson Comprehensive Cancer Center, David Geffen School of Medicine, University of California, Los Angeles, CA, USA.

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September 2014

NK cell phenotypic and functional heterogeneities and molecular mechanisms of cytotoxicity.

Crit Rev Oncog 2014 ;19(1-2):21-45

Department of Microbiology, Immunology and Molecular Genetics, Jonsson Comprehensive Cancer Center, David Geffen School of Medicine, University of California at Los Angeles, USA.

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September 2014

Raf kinase inhibitor protein (RKIP) blocks signal transducer and activator of transcription 3 (STAT3) activation in breast and prostate cancer.

PLoS One 2014 21;9(3):e92478. Epub 2014 Mar 21.

Department of Medicine, Rhode Island Hospital and The Alpert Medical School of Brown University, Providence, Rhode Island, United States of America.

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January 2015

Roles Each of Snail, Yin Yang 1 and RKIP in the Regulation of Tumor Cells Chemo-immuno-resistance to Apoptosis.

For Immunopathol Dis Therap 2013 ;4(1)

Department of Microbiology, Immunology & Molecular Genetics, David Geffen School of Medicine, University of California, Los Angeles.

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January 2013

Nitric oxide-mediated activity in anti-cancer photodynamic therapy.

Nitric Oxide 2013 Apr 26;30:26-35. Epub 2013 Jan 26.

Department of Medical and Biological Sciences, School of Medicine, University of Udine, P.le Kolbe 4, 33100 Udine, Italy.

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April 2013

Contribution of either YY1 or BclXL-induced inhibition by the NO-donor DETANONOate in the reversal of drug resistance, both in vitro and in vivo. YY1 and BclXL are overexpressed in prostate cancer.

Nitric Oxide 2013 Feb 11;29:17-24. Epub 2012 Dec 11.

Department of Microbiology, Immunology & Molecular Genetics, David Geffen School of Medicine, Jonsson Comprehensive Cancer Center, University of California at Los Angeles, Los Angeles, CA 90095, USA.

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February 2013

HIF-1 expression is associated with CCL2 chemokine expression in airway inflammatory cells: implications in allergic airway inflammation.

Respir Res 2012 Jul 23;13:60. Epub 2012 Jul 23.

Hospital Infantil de Mexico, Federico Gomez, Unidad de Investigacion en Enfermedades Oncologicas, Dr, Marquez No 262, Col, Doctores, Delegacion Cuahutemos, Mexico City CP 06720, Mexico.

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July 2012

TRAF6 activation in multiple myeloma: a potential therapeutic target.

Clin Lymphoma Myeloma Leuk 2012 Jun 21;12(3):155-63. Epub 2012 Mar 21.

Department of Microbiology, Immunology, and Molecular Genetics, Jonsson Comprehensive Cancer Center, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA, USA.

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June 2012

Galiximab signals B-NHL cells and inhibits the activities of NF-κB-induced YY1- and snail-resistant factors: mechanism of sensitization to apoptosis by chemoimmunotherapeutic drugs.

Mol Cancer Ther 2012 Mar 19;11(3):572-81. Epub 2012 Jan 19.

Corresponding Author: Benjamin Bonavida, Department of Microbiology, Immunology & Molecular Genetics, David Geffen School of Medicine, Jonsson Comprehensive Cancer Center, University of California, Los Angeles, CA 90095, USA.

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March 2012

The novel role of Yin Yang 1 in the regulation of epithelial to mesenchymal transition in cancer via the dysregulated NF-κB/Snail/YY1/RKIP/PTEN Circuitry.

Crit Rev Oncog 2011 ;16(3-4):211-26

Department of Microbiology, Immunology and Molecular Genetics, Jonsson Comprehensive Cancer Center, David Geffen School of Medicine, University of California at Los Angeles, USA.

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March 2012

Preface: special issue on yin yang 1 and oncogenesis.

Crit Rev Oncog 2011 ;16(3-4):141-2

Department of Microbiology, Immunology and Molecular Genetics, David Geffen School of Medicine, University of California, Los Angeles, California, USA.

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March 2012

Low circulating serum levels of second mitochondria-derived activator of caspase (Smac/DIABLO) in patients with bladder cancer.

Int J Oncol 2012 Apr 3;40(4):1246-50. Epub 2012 Jan 3.

Department of Urology, Faculty of Medicine, Osaka Medical College, 2-7 Daigakumachi, Takatsuki, Osaka 569-8686, Japan.

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April 2012

Inhibition of Epithelial-to-Mesenchymal Transition (EMT) in Cancer by Nitric Oxide: Pivotal Roles of Nitrosylation of NF-κB, YY1 and Snail.

For Immunopathol Dis Therap 2012 ;3(2):125-133

Department of Microbiology, Immunology & Molecular Genetics, David Geffen School of Medicine, Jonsson Comprehensive Cancer Center, University of California at Los Angeles, Los Angeles, California.

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January 2012

An antibody-based multifaceted approach targeting the human transferrin receptor for the treatment of B-cell malignancies.

J Immunother 2011 Jul-Aug;34(6):500-8

Division of Surgical Oncology, Department of Surgery, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA.

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October 2011

Development of rituximab-resistant B-NHL clones: an in vitro model for studying tumor resistance to monoclonal antibody-mediated immunotherapy.

Methods Mol Biol 2011 ;731:407-19

Department of Surgery, Jonsson Comprehensive Cancer Center, David Geffen School of Medicine, University of California, Los Angeles, CA, USA.

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August 2011

The anti-CD20 mAb LFB-R603 interrupts the dysregulated NF-κB/Snail/RKIP/PTEN resistance loop in B-NHL cells: role in sensitization to TRAIL apoptosis.

Int J Oncol 2011 Jun 23;38(6):1683-94. Epub 2011 Mar 23.

Department of Microbiology, Immunology and Molecular Genetics, David Geffen School of Medicine, Jonsson Comprehensive Cancer Center, University of California, Los Angeles, CA 90095-1747, USA.

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June 2011

Unique Pattern of Overexpression of Raf-1 Kinase Inhibitory Protein in Its Inactivated Phosphorylated Form in Human Multiple Myeloma.

For Immunopathol Dis Therap 2011 Apr;2(2)

Department of Microbiology, Immunology and Molecular Genetics, Jonsson Comprehensive Cancer Center, David Geffen School of Medicine, University of California, Los Angeles, CA.

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April 2011

Molecular mechanism of MART-1+/A*0201+ human melanoma resistance to specific CTL-killing despite functional tumor-CTL interaction.

Cancer Res 2011 Feb 15;71(4):1406-17. Epub 2010 Dec 15.

Department of Surgery, Molecular and Medical Pharmacology, Jonsson Comprehensive Cancer Center, David Geffen School of Medicine, University of California, Los Angeles, California, USA.

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February 2011

Mechanisms of nitric oxide-mediated inhibition of EMT in cancer: inhibition of the metastasis-inducer Snail and induction of the metastasis-suppressor RKIP.

Cell Cycle 2010 Dec 15;9(24):4931-40. Epub 2010 Dec 15.

Microbiology, Immunology and Molecular Genetics, Jonsson Comprehensive Cancer Center, University of California, Los Angeles, CA, USA.

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December 2010

Dual role of NO donors in the reversal of tumor cell resistance and EMT: Downregulation of the NF-κB/Snail/YY1/RKIP circuitry.

Nitric Oxide 2011 Jan 8;24(1):1-7. Epub 2010 Oct 8.

Department of Microbiology, Immunology, and Molecular Genetics, David Geffen School of Medicine, Johnson Comprehensive Cancer Center, University of California, Los Angeles, CA 90095, USA.

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January 2011

The Role of B-RAF Mutations in Melanoma and the Induction of EMT via Dysregulation of the NF-κB/Snail/RKIP/PTEN Circuit.

Genes Cancer 2010 May;1(5):409-420

Department of Microbiology, Immunology & Molecular Genetics, David Geffen School of Medicine, Jonsson Comprehensive Cancer Center, University of California at Los Angeles, Los Angeles, CA, USA.

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May 2010

Viral infection and cancer: the NF-kappaB/Snail/RKIP loop regulates target cell sensitivity to apoptosis by cytotoxic lymphocytes.

Crit Rev Immunol 2010 ;30(1):31-46

Department of Microbiology, Immunology and Molecular Genetics, Jonsson Comprehensive Cancer Center, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, California 90095, USA.

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October 2010

The proteasome inhibitor CEP-18770 enhances the anti-myeloma activity of bortezomib and melphalan.

Br J Haematol 2010 Feb 1;148(4):569-81. Epub 2009 Dec 1.

Institute for Myeloma & Bone Cancer Research, 9201 W. Sunset Boulevard, West Hollywood, CA 90069, USA.

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February 2010

Dysregulation of the cell survival/anti-apoptotic NF-kappaB pathway by the novel humanized BM-ca anti-CD20 mAb: implication in chemosensitization.

Int J Oncol 2009 Dec;35(6):1289-96

Department of Microbiology, Immunology and Molecular Genetics, Jonsson Comprehensive Cancer Center, David Geffen School of Medicine, University of California, Los Angeles, CA 90095, USA.

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December 2009

Rituximab-mediated cell signaling and chemo/immuno-sensitization of drug-resistant B-NHL is independent of its Fc functions.

Clin Cancer Res 2009 Nov 27;15(21):6582-94. Epub 2009 Oct 27.

Department of Microbiology, Immunology, and Molecular Genetics, Jonsson Comprehensive Cancer, David Geffen School of Medicine, University of California, Los Angeles, California 90095-1747, USA.

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November 2009

Pivotal roles of snail inhibition and RKIP induction by the proteasome inhibitor NPI-0052 in tumor cell chemoimmunosensitization.

Cancer Res 2009 Nov 20;69(21):8376-85. Epub 2009 Oct 20.

Department of Microbiology, Jonsson Comprehensive Cancer Center, David Geffen School of Medicine, University of California at Los Angeles, California 90095-736422, USA.

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November 2009

Higher expression levels of 14-3-3sigma in ductal carcinoma in situ of the breast predict poorer outcome.

Cancer Biomark 2009 ;5(4):215-24

Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095-1747, USA.

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November 2009

The activated NF-kappaB-Snail-RKIP circuitry in cancer regulates both the metastatic cascade and resistance to apoptosis by cytotoxic drugs.

Crit Rev Immunol 2009 ;29(3):241-54

Department of Microbiology, Immunology & Molecular Genetics, Jonsson Comprehensive Cancer Center, David Geffen School of Medicine, University of California at Los Angeles, Los Angeles, CA 90095-736422, USA.

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September 2009

Combination treatment of malignant B cells using the anti-CD20 antibody rituximab and the anti-malarial artesunate.

Int J Oncol 2009 Jul;35(1):149-58

German Cancer Research Center, Pharmaceutical Biology (C015), D-69120 Heidelberg, Germany.

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July 2009

BRAF and RKIP are significantly decreased in cutaneous squamous cell carcinoma.

Cell Cycle 2009 May 26;8(9):1402-8. Epub 2009 May 26.

Laboratory of Virology, Medical School, University of Crete, Heraklion, Crete, Greece.

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May 2009

Chemosensitization and immunosensitization of resistant cancer cells to apoptosis and inhibition of metastasis by the specific NF-kappaB inhibitor DHMEQ.

Curr Pharm Des 2009 ;15(7):792-808

Department of Microbiology, Immunology, and Molecular Genetics, David Geffen School of Medicine, Jonsson Comprehensive Cancer Center, University of California at Los Angeles, Los Angeles CA 90095, USA.

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April 2009

The NF-kappaB inhibitors (bortezomib and DHMEQ) sensitise rituximab-resistant AIDS-B-non-Hodgkin lymphoma to apoptosis by various chemotherapeutic drugs.

Leuk Lymphoma 2008 Oct;49(10):1982-94

Department of Microbiology, Immunology, and Molecular Genetics, University of California at Los Angeles, Los Angeles, California 90095-1747, USA.

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October 2008

Nitric oxide donors: novel cancer therapeutics (review).

Int J Oncol 2008 Nov;33(5):909-27

Department of Gastrointestinal and Endocrine Surgery, UT Southwestern Medical Center/VA North Texas Health Care System, Dallas, TX 75216, USA.

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November 2008

Nitric oxide sensitizes tumor cells to TRAIL-induced apoptosis via inhibition of the DR5 transcription repressor Yin Yang 1.

Nitric Oxide 2009 Feb 22;20(1):39-52. Epub 2008 Aug 22.

Department of Microbiology, Immunology and Molecular Genetics, Jonsson Comprehensive Cancer Center, David Geffen School of Medicine, University of California, 10833 Le Conte Avenue, A2-060, Los Angeles, CA 90095-73622, USA.

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February 2009

NF-kappaB in the pathogenesis and treatment of multiple myeloma.

Curr Opin Hematol 2008 Jul;15(4):391-9

Institute for Myeloma & Bone Cancer Research, West Hollywood, CA 90069, USA.

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July 2008

Novel therapeutic applications of nitric oxide donors in cancer: roles in chemo- and immunosensitization to apoptosis and inhibition of metastases.

Nitric Oxide 2008 Sep 24;19(2):152-7. Epub 2008 Apr 24.

Department of Microbiology, Immunology & Molecular Genetics, Jonsson Comprehensive Cancer Center, University of California at Los Angeles, 10833 Le Conte Avenue, Los Angeles, CA 90095-1747, USA.

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September 2008

Inhibition of Yin Yang 1-dependent repressor activity of DR5 transcription and expression by the novel proteasome inhibitor NPI-0052 contributes to its TRAIL-enhanced apoptosis in cancer cells.

J Immunol 2008 May;180(9):6199-210

Department of Microbiology, Immunology, and Molecular Genetics, Division of Surgical Oncology, David Geffen School of Medicine, University of California-Los Angeles, 10833 Le Conte Avenue, Los Angeles, CA 90095, USA.

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May 2008

Potentiation of cytotoxicity by combination of imatinib and chlorimipramine in glioma.

Int J Oncol 2008 Apr;32(4):829-39

Department of Histology and Embryology, Istanbul University, Istanbul Faculty of Medicine, 34093 Capa, Istanbul, Turkey.

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April 2008

Expression of X-linked inhibitor of apoptosis protein is a strong predictor of human prostate cancer recurrence.

Clin Cancer Res 2007 Oct;13(20):6056-63

Department of Pathology and Laboratory Medicine, Jonsson Comprehensive Cancer Center David Geffen School of Medicine at the University of California at Los Angeles, Los Angeles, California 90095-1747, USA.

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October 2007

Regulation of tumor cell sensitivity to TRAIL-induced apoptosis by the metastatic suppressor Raf kinase inhibitor protein via Yin Yang 1 inhibition and death receptor 5 up-regulation.

J Immunol 2007 Oct;179(8):5441-53

Department of Microbiology, Immunology, and Molecular Genetics, David Geffen School of Medicine, Jonsson Comprehensive Cancer Center, University of California, Los Angeles, CA 90095, USA.

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October 2007

The NO TRAIL to YES TRAIL in cancer therapy (review).

Int J Oncol 2007 Oct;31(4):685-91

Department of Microbiology, Immunology and Molecular Genetics, David Geffen School of Medicine, Jonsson Comprehensive Cancer Center, University of California at Los Angeles, Los Angeles, CA 90095-1747, USA.

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October 2007

Modification of gene products involved in resistance to apoptosis in metastatic colon cancer cells: roles of Fas, Apaf-1, NFkappaB, IAPs, Smac/DIABLO, and AIF.

J Surg Res 2007 Sep 2;142(1):184-94. Epub 2007 Jul 2.

Department of Gastrointestinal and Endocrine Surgery, University of Texas Southwestern Medical Center, Dallas, Texas 75216, USA.

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September 2007

Reversal of tumor resistance to apoptotic stimuli by alteration of membrane fluidity: therapeutic implications.

Adv Cancer Res 2007 ;98:149-90

Department of Microbiology, Immunology, and Molecular Genetics, Jonsson Comprehensive Cancer Center, David Geffen School of Medicine at UCLA, University of California, Los Angeles, California 90095, USA.

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May 2007

Chemotherapeutic drugs sensitize cancer cells to TRAIL-mediated apoptosis: up-regulation of DR5 and inhibition of Yin Yang 1.

Mol Cancer Ther 2007 Apr;6(4):1387-99

Department of Microbiology, Immunology and Molecular Genetics, David Geffen School of Medicine, Jonsson Comprehensive Cancer Center, University of California at Los Angeles, Los Angeles, CA, USA.

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April 2007

Reversal of resistance to cytotoxic cancer therapies: DHMEQ as a chemo-sensitizing and immuno-sensitizing agent.

Drug Resist Updat 2007 Feb-Apr;10(1-2):1-12. Epub 2007 Feb 15.

Department of Microbiology, Immunology, and Molecular Genetics, David Geffen School of Medicine, Jonsson Comprehensive Cancer Center, University of California at Los Angeles, CA 90095-1747, United States.

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June 2007

Development of rituximab-resistant lymphoma clones with altered cell signaling and cross-resistance to chemotherapy.

Cancer Res 2007 Feb;67(3):1270-81

Department of Microbiology, Immunology, and Molecular Genetics, Jonsson Comprehensive Cancer Center, David Geffen School of Medicine, University of California-Los Angeles, 10833 Le Conte Avenue, Los Angeles, CA 90024, USA.

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February 2007