Benjamin B Gelman

Benjamin B Gelman

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Benjamin B Gelman

Benjamin B Gelman

Publications by authors named "Benjamin B Gelman"

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White Matter Abnormalities Linked to Interferon, Stress Response, and Energy Metabolism Gene Expression Changes in Older HIV-Positive Patients on Antiretroviral Therapy.

Mol Neurobiol 2019 Nov 5. Epub 2019 Nov 5.

Department of Cancer Immunology and Virology, Dana-Farber Cancer Institute, CLS 1010, 450 Brookline Ave, Boston, MA, 02215, USA.

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http://dx.doi.org/10.1007/s12035-019-01795-3DOI Listing
November 2019

HIV-induced neuroinflammation: impact of PAR1 and PAR2 processing by Furin.

Cell Death Differ 2019 Oct 25;26(10):1942-1954. Epub 2019 Jan 25.

Laboratory of Biochemical Neuroendocrinology, Montreal Clinical Research Institute (affiliated to the University of Montreal), 110 Pine Ave West, Montreal, QC, H2W1R7, Canada.

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http://dx.doi.org/10.1038/s41418-018-0264-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6748122PMC
October 2019

Characteristics of motor dysfunction in longstanding HIV.

Clin Infect Dis 2019 Oct 7. Epub 2019 Oct 7.

Department of Neurology, Icahn School of Medicine at Mount Sinai (ISMMS), NY, NY.

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http://dx.doi.org/10.1093/cid/ciz986DOI Listing
October 2019

Correlates of HIV RNA concentrations in cerebrospinal fluid during antiretroviral therapy: a longitudinal cohort study.

Lancet HIV 2019 Jul 14;6(7):e456-e462. Epub 2019 Jun 14.

Department of Psychiatry, University of California San Diego, San Diego, CA, USA; Department of Medicine, University of California San Diego, San Diego, CA, USA. Electronic address:

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http://dx.doi.org/10.1016/S2352-3018(19)30143-2DOI Listing
July 2019

Structure-guided drug design identifies a BRD4-selective small molecule that suppresses HIV.

J Clin Invest 2019 07 22;129(8):3361-3373. Epub 2019 Jul 22.

Department of Microbiology and Immunology, University of Texas Medical Branch (UTMB), Galveston, Texas, USA.

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http://dx.doi.org/10.1172/JCI120633DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6668673PMC
July 2019

When do models of NeuroAIDS faithfully imitate "the real thing"?

J Neurovirol 2018 04 18;24(2):146-155. Epub 2017 Dec 18.

Department of Neurology, University of Pennsylvania, Philadelphia, PA, 19104-6140, USA.

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http://dx.doi.org/10.1007/s13365-017-0601-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5910470PMC
April 2018

Heme oxygenase-1 promoter region (GT)n polymorphism associates with increased neuroimmune activation and risk for encephalitis in HIV infection.

J Neuroinflammation 2018 Mar 6;15(1):70. Epub 2018 Mar 6.

Department of Neurology, Perelman School of Medicine, University of Pennsylvania, 415 Curie Boulevard, 280C Clinical Research Building, Philadelphia, PA, 19104, USA.

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http://dx.doi.org/10.1186/s12974-018-1102-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5838989PMC
March 2018

Friedreich Ataxia: Developmental Failure of the Dorsal Root Entry Zone.

J Neuropathol Exp Neurol 2017 Nov;76(11):969-977

Research Service, Veterans Affairs Medical Center, Albany, New York; Department of Pathology, Albany Medical College, Albany, New York; Department of Pathology and Laboratory Medicine, University of Texas Medical Branch, Galveston, Texas; Department of Neuroscience and Experimental Therapeutics, Albany Medical College, Albany, New York.

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http://dx.doi.org/10.1093/jnen/nlx087DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6440497PMC
November 2017

Measures of Physical and Mental Independence Among HIV-Positive Individuals: Impact of Substance Use Disorder.

AIDS Res Hum Retroviruses 2017 Oct 10;33(10):1048-1055. Epub 2017 Apr 10.

2 Department of Epidemiology, College of Public Health, University of Nebraska Medical Center , Omaha, Nebraska.

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http://dx.doi.org/10.1089/AID.2016.0269DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650716PMC
October 2017

Modeling brain lentiviral infections during antiretroviral therapy in AIDS.

J Neurovirol 2017 08 16;23(4):577-586. Epub 2017 May 16.

Division of Neurology, Department of Medicine, University of Alberta, Edmonton, Canada.

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http://dx.doi.org/10.1007/s13365-017-0530-3DOI Listing
August 2017

Heart and Nervous System Pathology in Compound Heterozygous Friedreich Ataxia.

J Neuropathol Exp Neurol 2017 Aug;76(8):665-675

Research Service, Veterans Affairs Medical Center, Albany, New York (ABB, AHK); Department of Pathology, Albany Medical Center, Albany, New York (JQ, AHK); Department of Pathology and Laboratory Medicine, University of Texas Medical Branch, Galveston, Texas (BBG); Department of Pediatrics and Neurology, University of Colorado, Aurora, Colorado (MY); and Centogene, Rostock, Germany (PB).

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http://dx.doi.org/10.1093/jnen/nlx047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5901083PMC
August 2017

Multilevel analysis of neuropathogenesis of neurocognitive impairment in HIV.

J Neurovirol 2016 08 4;22(4):431-41. Epub 2015 Dec 4.

Department of Psychiatry, University of California San Diego School of Medicine, La Jolla, CA, USA.

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http://dx.doi.org/10.1007/s13365-015-0410-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4893344PMC
August 2016

The significance of intercalated discs in the pathogenesis of Friedreich cardiomyopathy.

J Neurol Sci 2016 Aug 4;367:171-6. Epub 2016 Jun 4.

Department of Neuroscience and Experimental Therapeutics, Albany Medical College, Albany, NY, USA.

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http://dx.doi.org/10.1016/j.jns.2016.06.006DOI Listing
August 2016

Spinal Cord Ventral Horns and Lymphoid Organ Involvement in Powassan Virus Infection in a Mouse Model.

Viruses 2016 08 12;8(8). Epub 2016 Aug 12.

Department of Pathology, University of Texas Medical Branch, Galveston, TX 77555, USA.

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http://www.mdpi.com/1999-4915/8/8/220
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http://dx.doi.org/10.3390/v8080220DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4997582PMC
August 2016

Altered Oligodendrocyte Maturation and Myelin Maintenance: The Role of Antiretrovirals in HIV-Associated Neurocognitive Disorders.

J Neuropathol Exp Neurol 2015 Nov;74(11):1093-118

From the Department of Neuroscience, The Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania (BKJ, MVM); Department of Neurology, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania (BKJ, HM, JBG); Department of Pathology, School of Dental Medicine, University of Pennsylvania, Philadelphia, Pennsylvania (BKJ, PJG, CAE, MAE, KLJ-S); Pennington Biomedical Research Center, Louisiana State University System, Baton Rouge, Louisiana (AJB-K); Department of Pathology, University of Texas Medical Branch, Galveston, Texas (BBG) Department of Psychology, College of Liberal Arts, Temple University, Philadelphia, Pennsylvania (LAB); Center for Neurobiology and Behavior, Department of Psychiatry, The Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania (CP).

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http://dx.doi.org/10.1097/NEN.0000000000000255DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4608376PMC
November 2015

The role of chemokine C-C motif ligand 2 genotype and cerebrospinal fluid chemokine C-C motif ligand 2 in neurocognition among HIV-infected patients.

AIDS 2015 Jul;29(12):1483-91

aDepartment of Psychiatry and Biobehavioral Sciences bDepartment of Family Medicine cDepartment of Obstetrics & Gynecology dDepartment of Epidemiology and Microbiology eDepartment of Immunology & Human Genetics fDepartment of Neurology, University of California, Los Angeles gGreater Los Angeles VA Healthcare System, Los Angeles, California hDepartment of Neurology iDepartment of Pathology jDepartment of Neuroscience, Icahn School of Medicine at Mount Sinai, New York, New York kDepartment of Pathology lDepartment of Neuroscience mDepartment of Cell Biology, University of Texas Medical Branch, Galveston, Texas nDepartment of Psychiatry, University of California, San Diego, California, USA.

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http://dx.doi.org/10.1097/QAD.0000000000000706DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4573552PMC
July 2015

Neuropathology of HAND With Suppressive Antiretroviral Therapy: Encephalitis and Neurodegeneration Reconsidered.

Curr HIV/AIDS Rep 2015 Jun;12(2):272-9

Departments of Pathology and Neuroscience & Cell Biology, University of Texas Medical Branch, 301 University Blvd., Keiller 3.118A, Route 0609, Galveston, TX, 77555-0609, USA,

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http://dx.doi.org/10.1007/s11904-015-0266-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4427627PMC
June 2015

Primary Langerhans cell histiocytosis of the lacrimal gland in an adult.

Can J Ophthalmol 2015 Jun;50(3):e40-3

University of Texas Medical Branch in Galveston, Galveston, Tex.

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http://dx.doi.org/10.1016/j.jcjo.2015.02.007DOI Listing
June 2015

Absence of neurocognitive effect of hepatitis C infection in HIV-coinfected people.

Neurology 2015 Jan 10;84(3):241-50. Epub 2014 Dec 10.

From Washington University (D.B.C.), St. Louis, MO; University of California (F.V., Y.-T.K., D.R.F., S.L.L., I.G., R.K.H.), San Diego; University of Washington (A.C.C., C.M.M.), Seattle; University of Texas at Galveston (B.B.G.); Johns Hopkins University (J.C.M.), Baltimore, MD; and The Icahn School of Medicine at Mount Sinai (S.M., D.M.S.), New York, NY.

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http://www.neurology.org/cgi/doi/10.1212/WNL.000000000000115
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http://dx.doi.org/10.1212/WNL.0000000000001156DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4335996PMC
January 2015

Quantitative neuropathology associated with chronic manganese exposure in South African mine workers.

Neurotoxicology 2014 Dec 26;45:260-6. Epub 2013 Dec 26.

School of Public Health, Faculty of Health Sciences, University of the Witwatersrand, Parktown, South Africa; Department of Neurology, Washington University School of Medicine, Saint Louis, MO, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuro.2013.12.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4072755PMC
December 2014

Astrocyte elevated gene-1 is a novel modulator of HIV-1-associated neuroinflammation via regulation of nuclear factor-κB signaling and excitatory amino acid transporter-2 repression.

J Biol Chem 2014 Jul 22;289(28):19599-612. Epub 2014 May 22.

From the Department of Cell Biology and Immunology, University of North Texas Health Science Center, Fort Worth, Texas 76107 and

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http://dx.doi.org/10.1074/jbc.M114.567644DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4094071PMC
July 2014

Gp120 in the pathogenesis of human immunodeficiency virus-associated pain.

Ann Neurol 2014 Jun 28;75(6):837-50. Epub 2014 May 28.

Department of Neuroscience and Cell Biology, University of Texas Medical Branch, Galveston, TX.

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http://dx.doi.org/10.1002/ana.24139DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4077969PMC
June 2014

Asymptomatic HIV-associated neurocognitive impairment increases risk for symptomatic decline.

Neurology 2014 Jun 9;82(23):2055-62. Epub 2014 May 9.

From the University of California (I.G., D.R.F., R.D., S.P.W., F.V., R.J.E., S.L.L., T.D.M., J.H.A., J.A.M., I.A., A.G., C.F.-N., D.M.S., R.K.H.), San Diego; the University of Washington (A.C.C., C.M.M.), Seattle; Washington University (D.B.C.), St. Louis, MO; University of Texas Medical Branch (B.B.G.), Galveston; Johns Hopkins University (J.C.M.), Baltimore, MD; and The Icahn School of Medicine at Mount Sinai (S.M., D.M.S.), New York, NY.

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http://www.neurology.org/cgi/doi/10.1212/WNL.000000000000049
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http://dx.doi.org/10.1212/WNL.0000000000000492DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4118496PMC
June 2014

Wnt signaling in the pathogenesis of human HIV-associated pain syndromes.

J Neuroimmune Pharmacol 2013 Sep 5;8(4):956-64. Epub 2013 Jun 5.

Department of Neuroscience and Cell Biology, University of Texas Medical Branch, Galveston, TX 77555-1069, USA.

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http://dx.doi.org/10.1007/s11481-013-9474-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3743252PMC
September 2013

The neuropathology of HIV.

Handb Clin Neurol 2007 ;85:301-17

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http://dx.doi.org/10.1016/S0072-9752(07)85018-4DOI Listing
October 2012

Prefrontal dopaminergic and enkephalinergic synaptic accommodation in HIV-associated neurocognitive disorders and encephalitis.

J Neuroimmune Pharmacol 2012 Sep 6;7(3):686-700. Epub 2012 Mar 6.

Department of Pathology, University of Texas Medical Branch, 301 University Blvd., Galveston, TX 77555-0609, USA.

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http://dx.doi.org/10.1007/s11481-012-9345-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3419353PMC
September 2012

Chronic-pain-associated astrocytic reaction in the spinal cord dorsal horn of human immunodeficiency virus-infected patients.

J Neurosci 2012 Aug;32(32):10833-40

Department of Neuroscience and Cell Biology, University of Texas Medical Branch, Galveston, Texas 77555, USA.

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http://dx.doi.org/10.1523/JNEUROSCI.5628-11.2012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3470811PMC
August 2012

Substance abuse increases the risk of neuropathy in an HIV-infected cohort.

Muscle Nerve 2012 Apr;45(4):471-6

Department of Neurology, Mount Sinai School of Medicine, One Gustave L. Levy Place, Box 1052, New York, New York 10029, USA.

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http://dx.doi.org/10.1002/mus.23231DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3313074PMC
April 2012

Deregulation of microRNAs by HIV-1 Vpr protein leads to the development of neurocognitive disorders.

J Biol Chem 2011 Oct 4;286(40):34976-85. Epub 2011 Aug 4.

Department of Neurology, Molecular Studies of Neurodegenerative Diseases Laboratory, Temple University School of Medicine, Philadelphia, Pennsylvania 19140, USA.

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http://dx.doi.org/10.1074/jbc.M111.241547DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3186354PMC
October 2011

Efavirenz concentrations in CSF exceed IC50 for wild-type HIV.

J Antimicrob Chemother 2011 Feb 23;66(2):354-7. Epub 2010 Nov 23.

University of California San Diego, Skaggs School of Pharmacy and Pharmaceutical Sciences, San Diego, CA, USA.

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http://dx.doi.org/10.1093/jac/dkq434DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3019085PMC
February 2011

Pathology and pathogenesis of sensory neuropathy in Friedreich's ataxia.

Acta Neuropathol 2010 Jul 26;120(1):97-108. Epub 2010 Mar 26.

VA Medical Center, Albany, NY 12208, USA.

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http://dx.doi.org/10.1007/s00401-010-0675-0DOI Listing
July 2010

Synaptic proteins linked to HIV-1 infection and immunoproteasome induction: proteomic analysis of human synaptosomes.

J Neuroimmune Pharmacol 2010 Mar 20;5(1):92-102. Epub 2009 Aug 20.

Department of Pathology, University of Texas Medical Branch, 301 University Blvd, Galveston, TX 77555, USA.

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http://link.springer.com/10.1007/s11481-009-9168-0
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http://dx.doi.org/10.1007/s11481-009-9168-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2824116PMC
March 2010

Persistent hijacking of brain proteasomes in HIV-associated dementia.

Am J Pathol 2010 Feb 24;176(2):893-902. Epub 2009 Dec 24.

Department of Pathology, University of Texas Medical Branch, Galveston, TX 77555-0609, USA.

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http://dx.doi.org/10.2353/ajpath.2010.090390DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2808094PMC
February 2010

Molecular confirmation of Sappinia pedata as a causative agent of amoebic encephalitis.

J Infect Dis 2009 Apr;199(8):1139-42

Division of Parasitic Disease, National Center for Zoonotic, Vector-Borne, and Enteric Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia 30341, USA.

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http://jid.oxfordjournals.org/content/199/8/1139.full.pdf
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http://jid.oxfordjournals.org/lookup/doi/10.1086/597473
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http://dx.doi.org/10.1086/597473DOI Listing
April 2009

Low atazanavir concentrations in cerebrospinal fluid.

AIDS 2009 Jan;23(1):83-7

Skaggs School of Pharmacy andPharmaceutical Sciences, School of Medicine, Department of Pediatrics, University of California, San Diego, 9500 Gilman Drive, MC 0719, La Jolla, CA 92093-0719, USA.

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http://dx.doi.org/10.1097/QAD.0b013e328317a702DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2642983PMC
January 2009

Abnormal striatal dopaminergic synapses in National NeuroAIDS Tissue Consortium subjects with HIV encephalitis.

J Neuroimmune Pharmacol 2006 Dec 8;1(4):410-20. Epub 2006 Aug 8.

Department of Pathology, Route 0785, University of Texas Medical Branch, Galveston, Texas 77555-0785, USA.

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http://dx.doi.org/10.1007/s11481-006-9030-6DOI Listing
December 2006

Potential role for white matter lysosome expansion in HIV-associated dementia.

J Acquir Immune Defic Syndr 2005 Aug;39(4):422-5

Department of Pathology, University of Texas Medical Branch, Galveston, 77555, USA.

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http://dx.doi.org/10.1097/01.qai.0000164250.41475.f2DOI Listing
August 2005

Acquired neuronal channelopathies in HIV-associated dementia.

J Neuroimmunol 2004 Dec;157(1-2):111-9

Texas NeuroAIDS Research Center Department of Pathology, Rt 0785, University of Texas Medical Branch, Galveston, TX 77555-0785, USA.

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http://dx.doi.org/10.1016/j.jneuroim.2004.08.044DOI Listing
December 2004

Host genetic polymorphisms in human immunodeficiency virus-related neurologic disease.

J Neurovirol 2004 ;10 Suppl 1:67-73

Department of Neurology, University of Texas Southwestern Medical Center, Dallas, Texas 75390-9036, USA.

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http://dx.doi.org/10.1080/753312755DOI Listing
May 2004

Brain aging in acquired immunodeficiency syndrome: increased ubiquitin-protein conjugate is correlated with decreased synaptic protein but not amyloid plaque accumulation.

J Neurovirol 2004 Apr;10(2):98-108

Department of Pathology, The University of Texas Medical Branch, Galveston, Texas 77555-0785, USA.

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http://link.springer.com/10.1080/13550280490279816
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http://dx.doi.org/10.1080/13550280490279816DOI Listing
April 2004

Neuropathological and ultrastructural features of amebic encephalitis caused by Sappinia diploidea.

J Neuropathol Exp Neurol 2003 Oct;62(10):990-8

Texas Center for NeuroAIDS Research, Department of Pathology, University of Texas Medical Branch at Galveston, Rt. 0785, Galveston, TX 77555-0785, USA.

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http://dx.doi.org/10.1093/jnen/62.10.990DOI Listing
October 2003

Human microglial cell isolation from adult autopsy brain: brain pH, regional variation, and infection with human immunodeficiency virus type 1.

J Neurovirol 2003 Jun;9(3):346-57

Department of Pathology, The University of Texas Medical Branch, Galveston, Texas 77555-0609, USA.

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http://link.springer.com/10.1080/13550280390201056
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http://dx.doi.org/10.1080/13550280390201056DOI Listing
June 2003